Natural Product Target: DNA topoisomerase II alpha

Target ID:   NPT1044
Target Name:   DNA topoisomerase II alpha
Target Type:   Individual Protein
Organism of Target:   Homo sapiens
Target External ID:   Uniprot_ID:[ P11388]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC185498 Etoposide 92
NPC261012 Doxorubicin 5
NPC150943 4'-Demethylpodophyllotoxin 4
NPC20791 Quercetin 4
NPC257728 Novobiocin 4
NPC169749 Myricetin 3
NPC303644 Prunetin 3
NPC39426 Genistein 3
NPC50898 Apigenin 3
NPC72016 Kaempferol 3-O-(5-O-Acetyl-Alpha-D-Apiofuranosyl)-7-O-Alpha-L-Rhamnopyranoside 3
NPC116775 Kaempferol 3
NPC150164 Kaempferol 3-O-Beta-D-Apiofuranosyl-7-O-Alpha-L-Rhamnopyranoside 3
NPC129909 Camptothecin 3
NPC142415 Oleanolic_Acid 2
NPC215584 Elliptecine 2
NPC216361 Morin 2
NPC40530 Netropsin 2
NPC192638 Lupeol 2
NPC196753 Olean-12-En-3Beta,24-Diol 2
NPC51443 Fisetin 2
NPC208477 Ginsenoside Rd 1
NPC30397 3-O-Beta-D-Glucopyranosyl Quinovic Acid28-O-Beta-D-Glucopyranosyl Ester 1
NPC74618 Bastadin 14 1
NPC131479 Ginsenoside F3 1
NPC471920 Phyllanthusmins D 1
NPC208594 Ginsenoside Re 1
NPC218490 4',6,7,Trihydroxyisoflavone 1
NPC135730 Mansonone E 1
NPC474075 Acutissimalignan A 1
NPC208650 Ginsenoside Rb1 1
NPC274507 3-O-Beta-D-Glucopyranosyl Quinovic Acid 1
NPC167877 (23R,25R)-3,4-Seco-9Beta-H-Lanosta-4(28),7-Dien-26,23-Olid-3-Oic Acid 1
NPC14946 Ginsenoside Rb3 1
NPC240302 Methyl (2R,6R)-6-[(3R,3Ar,5As,6S,7S,9Br)-6-(3-Methoxy-3-Oxopropyl)-3A,6,9B-Trimethyl-7-Prop-1-En-2-Yl-1,2,3,4,5,5A,7,8-Octahydrocyclopenta[A]Naphthalen-3-Yl]-2-Methyl-4-Oxoheptanoate 1
NPC210296 n.a. 1
NPC276377 Kaempferol 3-O-Alpha-L-Arabinopyranosyl-7-O-Alpha-L-Rhamnopyranoside 1
NPC128244 Ascididemin 1
NPC16520 20(S)-Ginsenoside Rg2 1
NPC213190 Ginsenoside F5 1
NPC31907 Ginsenoside F2 1
NPC133391 (2R,6R)-6-[(3R,3Ar,5As,6S,7S,9Br)-6-(2-Carboxyethyl)-3A,6,9B-Trimethyl-7-Prop-1-En-2-Yl-1,2,3,4,5,5A,7,8-Octahydrocyclopenta[A]Naphthalen-3-Yl]-2-Methyl-4-Oxoheptanoic Acid 1
NPC215008 Naphthoquinone 1
NPC279121 Luteolin 1
NPC474140 (2R,4S,6R)-6-[(3R,3Ar,5As,6S,7S,9Br)-6-(3-Hydroxypropyl)-3A,6,9B-Trimethyl-7-Prop-1-En-2-Yl-1,2,3,4,5,5A,7,8-Octahydrocyclopenta[A]Naphthalen-3-Yl]-2-Methylheptane-1,4-Diol 1
NPC166858 Bakuchicin 1
NPC292265 Ciprofloxacin 1
NPC69279 Dehydroeburiconic Acid 1
NPC53744 Olean-12-En-3Bea,15Alpha,24-Triol 1
NPC69737 Gypenoside Xvii 1
NPC178383 Betulin 1
NPC223125 Ungeremine 1
NPC311092 Ganoderiol F 1
NPC83569 Dehydrotrametenonic Acid 1
NPC474989 Olean-12-En-3Beta,15Alpha-Diol 1
NPC185529 Oleanderolide 1
NPC25998 Aesculioside Iv-23D1 1
NPC316461 Simocyclinone D8 1
NPC8039 20(R)Ginsenoside Rg3 1
NPC473432 Amsacrine 1
NPC27765 Alpha-Amyrin 1
NPC10842 Demethylzeylasterone 1
NPC167037 Damara-20(22), 24-Dien-3, 6, 12-Trine 1
NPC189852 20(R)-Ginsenoside Rg2 1
NPC242895 Phloretin 1
NPC108342 n.a. 1
NPC33768 3Alpha,27-Dihydroxylup-20(29)-En-28-Oic Acid Methyl Ester 1
NPC246943 Kaempferol 3-O-Beta-D-Glucopyranosyl-7-O-Alpha-L-Rhamnopyranoside 1
NPC100391 Methyl (23R,25R)-3,4-Seco-9Beta-H-Lanosta-4(28),7-Dien-26,23-Olid-3-Oate 1
NPC109083 Curcumin 1
NPC247779 Echinatin 1
NPC100726 Makaluvamine A 1
NPC197425 5-Hydroxyflavone 1
NPC120123 (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-Hydroxy-17-[(2S)-2-Hydroxy-6-Methylhept-5-En-2-Yl]-4,4,8,10,14-Pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthren-3-Yl]Oxy]-6-(Hydroxymethyl)Oxan-3-Yl]Oxy-6-(Hydroxymethyl)Oxane-3,4,5-Triol 1
NPC207554 Tryptanthrin 1
NPC258547 21-O-Angeloy-3Beta,16Alpha,22Alpha,24,28-Pentahydroxyolean-12-Ene 1
NPC475635 Makaluvamine F 1
NPC471923 7-O-[(2,3,4-Tri-O-Acetyl)-A-Larabinopyranosyl)]Diphyllin 1

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