NPASS Compound

Natural Product: NPC468994

Natural Product ID	NPC468994
Common Name ? The InCHIKey will be temporarily assigned as the "Common Name" if no IUPAC name or alternative short name is available.	MWWSFMDVAYGXBV-RUELKSSGSA-N
IUPAC Name	n.a.
Synonyms
Synthetic Gene Cluster	n.a.
ChEMBL Identifier	n.a.
PubChem CID	443939
Chemical Classification	CHEMONTID:0000000 [Organic compounds] [CHEMONTID:0000261] Phenylpropanoids and polyketides [CHEMONTID:0002106] Anthracyclines

The Chemical Classification was calculated by Classyfire, a software for chemical taxonomy calculation. Reference: DOI:10.1186/s13321-016-0174-y.

Chemical Representations

RDKit 3D 70 73 0 0 0 0 0 0 0 0999 V2000 -4.5066 -2.2267 -1.6324 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.0383 -1.8634 -0.2607 C 0 0 1 0 0 0 0 0 0 0 0 0 -4.8910 -3.0299 0.6738 C 0 0 2 0 0 0 0 0 0 0 0 0 -3.9777 -2.6356 1.8049 C 0 0 2 0 0 0 0 0 0 0 0 0 -2.6600 -2.1067 1.2687 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.9463 -1.0097 0.2276 C 0 0 1 0 0 0 0 0 0 0 0 0 -4.3523 -0.7748 0.2605 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.3569 0.1725 0.5168 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.5541 0.7390 -0.4486 C 0 0 1 0 0 0 0 0 0 0 0 0 -2.2460 1.9987 -0.9138 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5513 3.2799 -0.6510 C 0 0 1 0 0 0 0 0 0 0 0 0 -0.8174 3.2304 0.6706 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2280 2.1484 0.4799 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1635 0.9367 -0.0680 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7877 -0.0238 -0.2338 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1199 0.1648 0.1215 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4935 1.3798 0.6668 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8838 1.6291 1.0555 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2525 2.7195 1.5519 O 0 0 0 0 0 0 0 0 0 0 0 0 4.8778 0.5831 0.8631 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2110 0.7776 1.2181 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1533 -0.2017 1.0401 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7527 -1.4006 0.4952 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4628 -1.6469 0.1296 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5243 -0.6541 0.3136 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1255 -0.8700 -0.0638 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8226 -1.9817 -0.5544 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0337 -2.8482 -0.4222 O 0 0 0 0 0 0 0 0 0 0 0 0 5.9927 -3.8685 -0.6131 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5325 2.3767 0.8446 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8762 3.6040 1.3883 O 0 0 0 0 0 0 0 0 0 0 0 0 0.4883 -1.2885 -0.7819 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.6012 3.5446 -1.7584 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2742 2.7373 -2.0775 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.6826 4.8098 -2.5223 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6826 5.6641 -2.0989 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.4172 4.3678 -0.5576 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.7871 -3.6533 2.7873 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.2724 -4.0754 -0.0518 O 0 0 0 0 0 0 0 0 0 0 0 0 0.6835 0.0000 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -5.3450 -2.6941 -2.1876 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.2035 -1.3321 -2.1884 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.7231 -3.0152 -1.5798 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.1205 -1.6027 -0.4247 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.8759 -3.3956 1.0493 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4681 -1.7545 2.3126 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1746 -2.9354 0.7287 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9869 -1.7677 2.0579 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7480 -1.4417 -0.7459 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5706 0.0397 -1.3136 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2855 2.0784 -0.4980 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4234 1.9757 -2.0341 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4553 2.9120 1.4994 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2889 4.1848 0.8625 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4702 1.7487 1.6453 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1934 -0.0260 1.3268 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4872 -2.1799 0.3508 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4949 -4.0994 0.3439 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5061 -4.7791 -0.9704 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7490 -3.5490 -1.3859 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4795 4.2572 0.8806 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2899 -1.3202 -1.7883 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2854 5.3630 -2.3887 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7992 4.6398 -3.6177 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3347 6.3729 -1.4953 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1724 4.2058 0.0599 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1496 -3.3564 3.7413 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3321 -4.4953 2.5316 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.8867 -4.7380 0.5598 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6835 0.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 2 3 1 0 3 4 1 0 4 5 1 0 5 6 1 0 6 7 1 0 6 8 1 0 8 9 1 0 9 10 1 0 10 11 1 0 11 12 1 0 12 13 1 0 13 14 2 0 14 15 1 0 15 16 2 0 16 17 1 0 17 18 1 0 18 19 2 0 18 20 1 0 20 21 2 0 21 22 1 0 22 23 2 0 23 24 1 0 24 25 2 0 25 26 1 0 26 27 2 0 24 28 1 0 28 29 1 0 17 30 2 0 30 31 1 0 15 32 1 0 11 33 1 0 33 34 2 0 33 35 1 0 35 36 1 0 11 37 1 1 4 38 1 0 3 39 1 0 7 2 1 0 14 9 1 0 26 16 1 0 30 13 1 0 25 20 1 0 1 41 1 0 1 42 1 0 1 43 1 0 2 44 1 6 3 45 1 1 4 46 1 1 5 47 1 0 5 48 1 0 6 49 1 6 9 50 1 6 10 51 1 0 10 52 1 0 12 53 1 0 12 54 1 0 21 55 1 0 22 56 1 0 23 57 1 0 29 58 1 0 29 59 1 0 29 60 1 0 31 61 1 0 32 62 1 0 35 63 1 0 35 64 1 0 36 65 1 0 37 66 1 0 38 67 1 0 38 68 1 0 39 69 1 0 40 70 1 0 M END

Standard InCHIKey	MWWSFMDVAYGXBV-RUELKSSGSA-N
Standard InCHI	InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
SMILES	C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]1C[C@@](Cc2c1c(c1c(C(=O)c3cccc(c3C1=O)OC)c2O)O)(C(=O)CO)O)N)O.Cl

Calculated Properties

Physi-Chem Properties

MedChem Properties

ADMET Properties (ADMETlab3.0)

ADMET: Absorption

ADMET: Distribution

ADMET: Metabolism

ADMET: Excretion

ADMET: Toxicity

Species Source

Organism ID	Organism Name	Taxonomy Level	Family	SuperKingdom	Isolation Part	Collection Location	Collection Time	Reference
NPO26409	Plakortis simplex	Species	Plakinidae	Eukaryota	n.a.	Caribbean	n.a.	PMID[10021943]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10344559]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10344578]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10348041]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10604756]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10695669]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10724004]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[10869194]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10994816]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[11099231]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[11132958]
NPO26409	Plakortis simplex	Species	Plakinidae	Eukaryota	n.a.	Taiwan	n.a.	PMID[11277748]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[11374972]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[11473415]
NPO18950	Cephalotaxus fortunei	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[12542368]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[14738393]
NPO17504	Chaerophyllum hirsutum	Species	Apiaceae	Eukaryota	Roots	n.a.	n.a.	PMID[15387667]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	Australian	n.a.	PMID[15497950]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[15813185]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[15844966]
NPO26409	Plakortis simplex	Species	Plakinidae	Eukaryota	n.a.	n.a.	n.a.	PMID[15921424]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[15974616]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16180833]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[1666120]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16724845]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16830891]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16872146]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17125235]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17315965]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17551212]
NPO20987	Penicillium janthinellum	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[17555349]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17608531]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17844998]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17887721]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17917237]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18044841]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18081255]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	Indonesian	n.a.	PMID[18081255]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18205372]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	Northwest Territories, Canada	1995	PMID[18327911]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18327911]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	leaves	n.a.	n.a.	PMID[18588343]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18666798]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18776684]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19007176]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19129624]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19191549]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[19331340]
NPO27058	Aspergillus ustus	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[19769341]
NPO27058	Aspergillus ustus	Species	Aspergillaceae	Eukaryota	Suberites domuncula	n.a.	n.a.	PMID[19778087]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19856955]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19883065]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[20092333]
NPO29948	Penicillium purpurogenum	Species	Trichocomaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[2010354]
NPO40441	Aschersonia paraphysata BCC 11964	Strain	Clavicipitaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[20364867]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[20545334]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[20836523]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21028889]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21028891]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	mycelium	n.a.	PMID[21090727]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21314175]
NPO27058	Aspergillus ustus	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[21348461]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	mycelium	n.a.	PMID[21639131]
NPO15994	Dichotella gemmacea	Species	Ellisellidae	Eukaryota	n.a.	South China Sea	n.a.	PMID[21721519]
NPO15994	Dichotella gemmacea	Species	Ellisellidae	Eukaryota	n.a.	n.a.	n.a.	PMID[21721519]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21728289]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	latex	n.a.	PMID[21751787]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21807523]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21873059]
NPO29948	Penicillium purpurogenum	Species	Trichocomaceae	Eukaryota	n.a.	mycelium	n.a.	PMID[21879714]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	latex	n.a.	PMID[21879726]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	mycelium	n.a.	PMID[22145663]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[22574670]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[22583058]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[22591466]
NPO15994	Dichotella gemmacea	Species	Ellisellidae	Eukaryota	n.a.	South China Sea	n.a.	PMID[22647719]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[22758660]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[22775474]
NPO13214	Ipomoea alba	Species	Convolvulaceae	Eukaryota	seeds	n.a.	n.a.	PMID[22924480]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[23387796]
NPO15994	Dichotella gemmacea	Species	Ellisellidae	Eukaryota	n.a.	n.a.	n.a.	PMID[23477504]
NPO40602	Streptomyces sp. CHQ-64	Strain	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[23547884]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[23662937]
NPO26409	Plakortis simplex	Species	Plakinidae	Eukaryota	n.a.	n.a.	n.a.	PMID[23806071]
NPO27058	Aspergillus ustus	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[24033077]
NPO11517	Streptomyces violascens	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[24182355]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[24592993]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[24754815]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[24878306]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[24964393]
NPO26409	Plakortis simplex	Species	Plakinidae	Eukaryota	n.a.	China	n.a.	PMID[25115700]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25211234]
NPO40252	Notoscyphus lutescens	Species	Notoscyphaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[25226363]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25455147]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25495422]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25537064]
NPO13847	Streptomyces avermectinius	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25611131]
NPO27058	Aspergillus ustus	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[25706180]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25918793]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25934225]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[26035239]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[26465675]
NPO40456	Aspergillus versicolor HDN1009	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[26506221]
NPO40759	Okeania sp.	Species	Oscillatoriaceae	Bacteria	n.a.	n.a.	n.a.	PMID[26539973]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[26798949]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[26905826]
NPO40536	Streptomyces albolongus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[26933756]
NPO40599	Saccharothrix sp. A1506	Strain	Pseudonocardiaceae	Bacteria	n.a.	n.a.	n.a.	PMID[27332142]
NPO40759	Okeania sp.	Species	Oscillatoriaceae	Bacteria	n.a.	n.a.	n.a.	PMID[27359053]
NPO40568	Mucor irregularis QEN-189	Strain	Mucoraceae	Eukaryota	n.a.	n.a.	n.a.	PMID[27462726]
NPO41065	Floricola striata	Species	Teichosporaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[27557136]
NPO40481	Corallococcus coralloides M23	Strain	Myxococcaceae	Bacteria	n.a.	n.a.	n.a.	PMID[27598688]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[27700077]
NPO17974	Sarcophyton subviride	Species	Orchidaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[27704808]
NPO40445	Aspergillus flavipes HN4-13	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[27933892]
NPO40985	Penicillium janthinellum HDN13-309	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[27992183]
NPO15190	Chloranthus fortunei	Species	Chloranthaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[27997206]
NPO13214	Ipomoea alba	Species	Convolvulaceae	Eukaryota	Seeds	n.a.	n.a.	PMID[28006904]
NPO18950	Cephalotaxus fortunei	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[28139925]
NPO11517	Streptomyces violascens	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[28206772]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[28225280]
NPO40759	Okeania sp.	Species	Oscillatoriaceae	Bacteria	n.a.	n.a.	n.a.	PMID[28294609]
NPO40602	Streptomyces sp. CHQ-64	Strain	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[28418245]
NPO1692	Aquilaria malaccensis	Species	Thymelaeaceae	Eukaryota	Seeds	n.a.	n.a.	PMID[28445049]
NPO40759	Okeania sp.	Species	Oscillatoriaceae	Bacteria	n.a.	n.a.	n.a.	PMID[28541699]
NPO40759	Okeania sp.	Species	Oscillatoriaceae	Bacteria	n.a.	n.a.	n.a.	PMID[29019684]
NPO1692	Aquilaria malaccensis	Species	Thymelaeaceae	Eukaryota	Agarwood	n.a.	n.a.	PMID[29083898]
NPO4490	Cephalotaxus sinensis	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[29182349]
NPO40915	Radula sumatrana	Species	Radulaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[29215886]
NPO27058	Aspergillus ustus	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[29286660]
NPO40613	Penicillium sp. HJ002	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[29489361]
NPO40521	Garcinia bracteata	Species	Clusiaceae	Eukaryota	Leaves	n.a.	n.a.	PMID[29565129]
NPO40759	Okeania sp.	Species	Oscillatoriaceae	Bacteria	n.a.	n.a.	n.a.	PMID[29667822]
NPO40277	Perenniporia maackiae	Species	Polyporaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[29878761]
NPO40478	Cladosporium sphaerospermum L3P3	Strain	Cladosporiaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[29985604]
NPO41065	Floricola striata	Species	Teichosporaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[30137985]
NPO40640	Streptomyces sp. SC0581	Strain	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[30222343]
NPO1692	Aquilaria malaccensis	Species	Thymelaeaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[30672698]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[31013087]
NPO4055	Aspergillus unguis	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31117521]
NPO40822	Croton damayeshu	Species	Euphorbiaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31117522]
NPO18950	Cephalotaxus fortunei	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31184894]
NPO40314	Radula constricta	Species	Radulaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31268321]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[31298537]
NPO23429	Lycium barbarum	Species	Solanaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31397570]
NPO40712	Streptomyces sp. SSA28	Strain	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[31436991]
NPO20987	Penicillium janthinellum	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31668073]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31789520]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31804070]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[31894983]
NPO40443	Aspergillus candidus LDJ-5	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31904949]
NPO40759	Okeania sp.	Species	Oscillatoriaceae	Bacteria	n.a.	n.a.	n.a.	PMID[32040324]
NPO40759	Okeania sp.	Species	Oscillatoriaceae	Bacteria	n.a.	n.a.	n.a.	PMID[32173199]
NPO40759	Okeania sp.	Species	Oscillatoriaceae	Bacteria	n.a.	n.a.	n.a.	PMID[32267694]
NPO29948	Penicillium purpurogenum	Species	Trichocomaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[32293887]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[32298122]
NPO40388	Umbilicaria sp.	Species	Umbilicariaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[32394716]
NPO40685	Streptomyces sp. HDN15129	Strain	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[32840364]
NPO24414	Trichoderma harzianum	Species	Hypocreaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[33301677]
NPO23429	Lycium barbarum	Species	Solanaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[37446592]
NPO23429	Lycium barbarum	Species	Solanaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[38961030]
NPO13847	Streptomyces avermectinius	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[464561]
NPO1692	Aquilaria malaccensis	Species	Thymelaeaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[7320738]
NPO24414	Trichoderma harzianum	Species	Hypocreaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[8201317]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[8501018]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	mycelium	n.a.	PMID[8784423]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[8931733]
NPO24414	Trichoderma harzianum	Species	Hypocreaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[8968392]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[8982334]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9031666]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9031676]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9066767]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9066768]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9186568]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9531983]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	mycelium	n.a.	PMID[9711246]
NPO4055	Aspergillus unguis	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO23429	Lycium barbarum	Species	Solanaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO13847	Streptomyces avermectinius	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO18950	Cephalotaxus fortunei	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO17974	Sarcophyton subviride	Species	Orchidaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO26409	Plakortis simplex	Species	Plakinidae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40602	Streptomyces sp. CHQ-64	Strain	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO11517	Streptomyces violascens	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO24414	Trichoderma harzianum	Species	Hypocreaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO27058	Aspergillus ustus	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40536	Streptomyces albolongus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO20987	Penicillium janthinellum	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO15190	Chloranthus fortunei	Species	Chloranthaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO1692	Aquilaria malaccensis	Species	Thymelaeaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO17504	Chaerophyllum hirsutum	Species	Apiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO29948	Penicillium purpurogenum	Species	Trichocomaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO4490	Cephalotaxus sinensis	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO13214	Ipomoea alba	Species	Convolvulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40314	Radula constricta	Species	Radulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40685	Streptomyces sp. HDN15129	Strain	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40456	Aspergillus versicolor HDN1009	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40985	Penicillium janthinellum HDN13-309	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40481	Corallococcus coralloides M23	Strain	Myxococcaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO15994	Dichotella gemmacea	Species	Ellisellidae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40759	Okeania sp.	Species	Oscillatoriaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40568	Mucor irregularis QEN-189	Strain	Mucoraceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40599	Saccharothrix sp. A1506	Strain	Pseudonocardiaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40478	Cladosporium sphaerospermum L3P3	Strain	Cladosporiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40443	Aspergillus candidus LDJ-5	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO41065	Floricola striata	Species	Teichosporaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40277	Perenniporia maackiae	Species	Polyporaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40712	Streptomyces sp. SSA28	Strain	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40445	Aspergillus flavipes HN4-13	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40388	Umbilicaria sp.	Species	Umbilicariaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO40640	Streptomyces sp. SC0581	Strain	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO18950	Cephalotaxus fortunei	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO23429	Lycium barbarum	Species	Solanaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO4490	Cephalotaxus sinensis	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO18950	Cephalotaxus fortunei	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO4490	Cephalotaxus sinensis	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO23429	Lycium barbarum	Species	Solanaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO4055	Aspergillus unguis	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO23429	Lycium barbarum	Species	Solanaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCM_Taiwan]
NPO18950	Cephalotaxus fortunei	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCM_Taiwan]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCM_Taiwan]
NPO4490	Cephalotaxus sinensis	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCM_Taiwan]
NPO23429	Lycium barbarum	Species	Solanaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TM-MC]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TM-MC]
NPO13847	Streptomyces avermectinius	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[UNPD]
NPO18950	Cephalotaxus fortunei	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO4055	Aspergillus unguis	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO15190	Chloranthus fortunei	Species	Chloranthaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO26409	Plakortis simplex	Species	Plakinidae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO17974	Sarcophyton subviride	Species	Orchidaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO1692	Aquilaria malaccensis	Species	Thymelaeaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO4490	Cephalotaxus sinensis	Species	Taxaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO13214	Ipomoea alba	Species	Convolvulaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO23429	Lycium barbarum	Species	Solanaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO15994	Dichotella gemmacea	Species	Ellisellidae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO17504	Chaerophyllum hirsutum	Species	Apiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO24414	Trichoderma harzianum	Species	Hypocreaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO14112	Uncaria rhynchophylla	Species	Rubiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO20987	Penicillium janthinellum	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO27058	Aspergillus ustus	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]

Note for Reference:
In addition to directly collecting NP source organism data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated them from below databases:
☉ UNPD: Universal Natural Products Database [PMID: 23638153].
☉ StreptomeDB: a database of streptomycetes natural products [PMID: 33051671].
☉ TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine [PMID: 26156871].
☉ TCM@Taiwan: a Traditional Chinese Medicine database [PMID: 21253603].
☉ TCMID: a Traditional Chinese Medicine database [PMID: 29106634].
☉ TCMSP: The traditional Chinese medicine systems pharmacology database and analysis platform [PMID: 24735618].
☉ HerDing: a herb recommendation system to treat diseases using genes and chemicals [PMID: 26980517].
☉ MetaboLights: a metabolomics database [PMID: 27010336].
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

NP Quantity Composition/Concentration

Organism ID	Organism Name	Organism Material Preparation	Organism Part	NP Quantity (Standard)	NP Quantity (Minimum)	NP Quantity (Maximum)	Quantity Unit	Reference

Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP quantitative records for specific NP domains (e.g., NPS from foods or herbs) from domain-specific databases. These databases include:
☉ DUKE: Dr. Duke's Phytochemical and Ethnobotanical Databases.
☉ PHENOL EXPLORER: is the first comprehensive database on polyphenol content in foods [PMID: 24103452], its homepage can be accessed at here.
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

Biological Activity

Activity Type	# Activity
ED50	21
Inhibition	34
FC	5
IC50	817
Activity	105
Kb	3
EC50	8
GI50	133
GI	31
TGI	24
Ratio IC50	42
MIC	7
CC50	3
ID50	3
Ratio	1

Activity Type	# Activity
Individual protein	8
Cell line	1047
Nucleic-acid	2
Organism	17
Unchecked	16
Nucleic acid	2
Single protein	1
Non-molecular	106
Others	38

Molecular-level activity

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT2732	Individual protein	Aldehyde dehydrogenase	Homo sapiens	Activity	=	0.964	%	PMID[29656202]
NPT2732	Individual protein	Aldehyde dehydrogenase	Homo sapiens	Activity	=	18.8	%	PMID[29656202]
NPT1044	Individual protein	DNA topoisomerase II alpha	Homo sapiens	IC50	=	940.0	nM	PMID[32527548]
NPT21577	Nucleic-acid	quadruplex DNA	Homo sapiens	Kb	=	1.1	10'6/M	PMID[31685331]
NPT21577	Nucleic-acid	quadruplex DNA	Homo sapiens	Kb	=	0.6	10'6/M	PMID[31685331]
NPT317	Nucleic acid	Nucleic Acid	n.a.	ED50	=	1.6	uM	PMID[6716401]
NPT317	Nucleic acid	Nucleic Acid	n.a.	ED50	=	0.58	uM	PMID[6716401]
NPT67	Individual protein	Cholinesterase	Equus caballus	Inhibition	=	1.2	%	PMID[23062825]
NPT20556	Single protein	Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	29.52	%	DOI[10.6019/CHEMBL4495564]
NPT66	Individual protein	Acetylcholinesterase	Electrophorus electricus	Inhibition	=	10.38	%	PMID[23062825]
NPT668	Individual protein	P-glycoprotein 1	Homo sapiens	FC	=	1.0	n.a.	PMID[28645831]
NPT668	Individual protein	P-glycoprotein 1	Homo sapiens	IC50	=	96910.0	nM	PMID[28645831]
NPT604	Individual protein	Serum albumin	Homo sapiens	Kb	=	3.0	10'3/M	PMID[31685331]

In vitro activity

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT168	Cell line	P388	Mus musculus	IC50	=	17.0	nM	PMID[14736253]
NPT81	Cell line	A549	Homo sapiens	ED50	=	6.2	uM	PMID[10091695]
NPT4247	Cell line	MCF7R	Homo sapiens	ED50	=	0.6	uM	PMID[10091695]
NPT139	Cell line	HT-29	Homo sapiens	ED50	=	3.7	uM	PMID[10091695]
NPT376	Cell line	A498	Homo sapiens	ED50	=	3.5	uM	PMID[10091695]
NPT306	Cell line	PC-3	Homo sapiens	ED50	=	5.7	uM	PMID[10091695]
NPT783	Cell line	MIA PaCa-2	Homo sapiens	ED50	=	6.3	uM	PMID[10091695]
NPT83	Cell line	MCF7	Homo sapiens	ED50	=	3.4	uM	PMID[10091695]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	ED50	=	1.5	uM	PMID[10091695]
NPT137	Cell line	L1210	Mus musculus	ED50	=	1.5	uM	PMID[7252976]
NPT137	Cell line	L1210	Mus musculus	ED50	=	0.7	uM	PMID[7252976]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	0.00323	ug.mL-1	PMID[15324908]
NPT137	Cell line	L1210	Mus musculus	ED50	=	0.1	uM	PMID[15982876]
NPT111	Cell line	K562	Homo sapiens	IC50	=	10.0	nM	PMID[17973361]
NPT180	Cell line	HCT-8	Homo sapiens	ED50	=	0.3	ug ml-1	PMID[2095375]
NPT453	Cell line	HT-1080	Homo sapiens	IC50	=	200.0	nM	PMID[11575942]
NPT91	Cell line	KB	Homo sapiens	IC50	=	10.0	ug.mL-1	PMID[17512094]
NPT81	Cell line	A549	Homo sapiens	IC50	=	0.15	ug.mL-1	PMID[9214732]
NPT180	Cell line	HCT-8	Homo sapiens	IC50	=	0.3	ug.mL-1	PMID[9214732]
NPT453	Cell line	HT-1080	Homo sapiens	ED50	=	0.034	ug ml-1	PMID[9677271]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	10.0	nM	PMID[15387667]
NPT453	Cell line	HT-1080	Homo sapiens	IC50	=	12.0	nM	PMID[15387667]
NPT114	Cell line	LoVo	Homo sapiens	IC50	=	200.0	nM	PMID[15387667]
NPT114	Cell line	LoVo	Homo sapiens	IC50	=	13200.0	nM	PMID[15387667]
NPT453	Cell line	HT-1080	Homo sapiens	EC50	=	20.0	nM	PMID[12027739]
NPT81	Cell line	A549	Homo sapiens	EC50	=	40.0	nM	PMID[12027739]
NPT165	Cell line	HeLa	Homo sapiens	EC50	=	20.0	nM	PMID[12027739]
NPT1374	Cell line	WI-38	Homo sapiens	IC50	=	700.0	nM	PMID[17067155]
NPT1475	Cell line	WI-38 VA13	Homo sapiens	IC50	=	400.0	nM	PMID[17067155]
NPT168	Cell line	P388	Mus musculus	IC50	=	0.1	ug.mL-1	PMID[10579858]
NPT81	Cell line	A549	Homo sapiens	IC50	=	0.025	ug.mL-1	PMID[10579858]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	0.5	ug.mL-1	PMID[10579858]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	231.0	nM	PMID[16562842]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	25650.0	nM	PMID[16562842]
NPT111	Cell line	K562	Homo sapiens	IC50	=	1200.0	nM	PMID[19256529]
NPT90	Cell line	DU-145	Homo sapiens	Inhibition	=	70.3	%	PMID[19800803]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	1300.0	nM	PMID[19954977]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	5750.0	nM	PMID[19954977]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	1100.0	nM	PMID[19954977]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	1160.0	nM	PMID[19954977]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1600.0	nM	PMID[19954977]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	180.0	nM	PMID[19962306]
NPT111	Cell line	K562	Homo sapiens	GI50	=	0.375	ug.mL-1	PMID[20045644]
NPT5528	Cell line	MOLT-4F	Homo sapiens	GI50	=	0.277	ug.mL-1	PMID[20045644]
NPT404	Cell line	CCRF-CEM	Homo sapiens	GI50	=	0.181	ug.mL-1	PMID[20045644]
NPT116	Cell line	HL-60	Homo sapiens	GI50	=	0.413	ug.mL-1	PMID[20045644]
NPT407	Cell line	COLO 205	Homo sapiens	GI50	=	0.523	ug.mL-1	PMID[20045644]
NPT373	Cell line	SK-MEL-5	Homo sapiens	GI50	=	0.481	ug.mL-1	PMID[20045644]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	710.0	nM	PMID[20093033]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	950.0	nM	PMID[20093033]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	940.0	nM	PMID[20093033]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	1190.0	nM	PMID[20093033]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	3150.0	nM	PMID[20093033]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	1980.0	nM	PMID[20188578]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1820.0	nM	PMID[20188578]
NPT83	Cell line	MCF7	Homo sapiens	Inhibition	=	1.25	%	PMID[20188578]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	2320.0	nM	PMID[20188578]
NPT111	Cell line	K562	Homo sapiens	IC50	=	2450.0	nM	PMID[20188578]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	2120.0	nM	PMID[19939682]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1130.0	nM	PMID[19939682]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	1500.0	nM	PMID[19939682]
NPT111	Cell line	K562	Homo sapiens	IC50	=	2500.0	nM	PMID[19939682]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	2100.0	nM	PMID[19939682]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	650.0	nM	PMID[19618898]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1080.0	nM	PMID[19836231]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	3900.0	nM	PMID[19836231]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	2540.0	nM	PMID[19836231]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	1670.0	nM	PMID[19836231]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	880.0	nM	PMID[19836231]
NPT83	Cell line	MCF7	Homo sapiens	GI	=	72.0	%	PMID[20188544]
NPT399	Cell line	SF-295	Homo sapiens	GI	=	69.0	%	PMID[20188544]
NPT111	Cell line	K562	Homo sapiens	IC50	=	430.0	nM	PMID[20353152]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	390.0	nM	PMID[20353152]
NPT639	Cell line	NCI-H187	Homo sapiens	IC50	=	86.0	nM	PMID[20364867]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1500.0	nM	PMID[20364867]
NPT91	Cell line	KB	Homo sapiens	IC50	=	280.0	nM	PMID[20364867]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	220.0	nM	PMID[20133021]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	100.0	nM	PMID[20133021]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	80.0	nM	PMID[20133021]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	6200.0	nM	PMID[20133021]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1300.0	nM	PMID[20133021]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1000.0	nM	PMID[20133021]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	80.0	nM	PMID[20133021]
NPT116	Cell line	HL-60	Homo sapiens	Activity	=	83.0	%	PMID[20133021]
NPT116	Cell line	HL-60	Homo sapiens	Activity	=	28.0	%	PMID[20133021]
NPT116	Cell line	HL-60	Homo sapiens	Activity	=	2.8	%	PMID[20133021]
NPT116	Cell line	HL-60	Homo sapiens	Activity	=	5.6	%	PMID[20133021]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	400.0	nM	PMID[20392646]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1000.0	nM	PMID[20392646]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	1000.0	nM	PMID[20392646]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	1200.0	nM	PMID[20392646]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	700.0	nM	PMID[20392646]
NPT81	Cell line	A549	Homo sapiens	GI50	=	7250.0	nM	PMID[20444601]
NPT379	Cell line	HOP-62	Homo sapiens	GI50	=	140.0	nM	PMID[20444601]
NPT133	Cell line	ZR-75-1	Homo sapiens	GI50	=	1790.0	nM	PMID[20444601]
NPT83	Cell line	MCF7	Homo sapiens	GI50	=	170.0	nM	PMID[20444601]
NPT91	Cell line	KB	Homo sapiens	GI50	=	170.0	nM	PMID[20444601]
NPT306	Cell line	PC-3	Homo sapiens	GI50	=	1810.0	nM	PMID[20444601]
NPT179	Cell line	A2780	Homo sapiens	GI50	=	160.0	nM	PMID[20444601]
NPT407	Cell line	COLO 205	Homo sapiens	GI50	=	140.0	nM	PMID[20444601]
NPT2245	Cell line	SiHa	Homo sapiens	GI50	=	170.0	nM	PMID[20444601]
NPT2307	Cell line	769-P	Homo sapiens	IC50	=	11500.0	nM	PMID[20627721]
NPT91	Cell line	KB	Homo sapiens	IC50	=	600.0	nM	PMID[20627721]
NPT401	Cell line	786-0	Homo sapiens	IC50	=	3100.0	nM	PMID[20627721]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	1000.0	nM	PMID[20627721]
NPT1083	Cell line	A-375	Homo sapiens	IC50	=	17200.0	nM	PMID[20627721]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	4200.0	nM	PMID[20627721]
NPT1997	Cell line	OS-RC-2	Homo sapiens	IC50	<	1000.0	nM	PMID[20627721]
NPT1629	Cell line	CWR22R	Homo sapiens	IC50	<	1000.0	nM	PMID[20627721]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	5100.0	nM	PMID[20627721]
NPT111	Cell line	K562	Homo sapiens	IC50	=	10.0	nM	PMID[20537765]
NPT111	Cell line	K562	Homo sapiens	IC50	=	10.0	nM	PMID[20546980]
NPT91	Cell line	KB	Homo sapiens	IC50	=	1.66	ug.mL-1	PMID[20724170]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	4400.0	nM	PMID[20619511]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	18900.0	nM	PMID[20619511]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	4000.0	nM	PMID[20619511]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	1400.0	nM	PMID[20619511]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	10100.0	nM	PMID[20619511]
NPT81	Cell line	A549	Homo sapiens	GI50	<	100.0	nM	PMID[20554354]
NPT379	Cell line	HOP-62	Homo sapiens	GI50	=	120.0	nM	PMID[20554354]
NPT407	Cell line	COLO 205	Homo sapiens	GI50	=	130.0	nM	PMID[20554354]
NPT306	Cell line	PC-3	Homo sapiens	GI50	=	160.0	nM	PMID[20554354]
NPT83	Cell line	MCF7	Homo sapiens	GI50	<	100.0	nM	PMID[20554354]
NPT133	Cell line	ZR-75-1	Homo sapiens	GI50	=	120.0	nM	PMID[20554354]
NPT179	Cell line	A2780	Homo sapiens	GI50	<	100.0	nM	PMID[20554354]
NPT91	Cell line	KB	Homo sapiens	GI50	=	130.0	nM	PMID[20554354]
NPT2245	Cell line	SiHa	Homo sapiens	GI50	=	150.0	nM	PMID[20554354]
NPT91	Cell line	KB	Homo sapiens	GI50	=	160.0	nM	PMID[20557981]
NPT2245	Cell line	SiHa	Homo sapiens	GI50	=	1900.0	nM	PMID[20557981]
NPT133	Cell line	ZR-75-1	Homo sapiens	GI50	<	100.0	nM	PMID[20557981]
NPT179	Cell line	A2780	Homo sapiens	GI50	<	100.0	nM	PMID[20557981]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	680.0	nM	PMID[21123066]
NPT81	Cell line	A549	Homo sapiens	IC50	=	540.0	nM	PMID[21123066]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1650.0	nM	PMID[21123066]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1350.0	nM	PMID[21123066]
NPT547	Cell line	BGC-823	Homo sapiens	IC50	=	1330.0	nM	PMID[21123066]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	2260.0	nM	PMID[21144747]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	2080.0	nM	PMID[21144747]
NPT3140	Cell line	MGC-803	Homo sapiens	IC50	=	2530.0	nM	PMID[21144747]
NPT407	Cell line	COLO 205	Homo sapiens	IC50	=	5100.0	nM	PMID[21144748]
NPT379	Cell line	HOP-62	Homo sapiens	IC50	=	5400.0	nM	PMID[21144748]
NPT453	Cell line	HT-1080	Homo sapiens	IC50	=	4700.0	nM	PMID[21144748]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	100.0	nM	PMID[21090801]
NPT83	Cell line	MCF7	Homo sapiens	Inhibition	=	98.0	%	PMID[21090801]
NPT83	Cell line	MCF7	Homo sapiens	Inhibition	=	76.0	%	PMID[21090801]
NPT83	Cell line	MCF7	Homo sapiens	Inhibition	=	69.0	%	PMID[21090801]
NPT116	Cell line	HL-60	Homo sapiens	Inhibition	=	100.0	%	PMID[21090801]
NPT116	Cell line	HL-60	Homo sapiens	Inhibition	=	89.0	%	PMID[21090801]
NPT83	Cell line	MCF7	Homo sapiens	IC50	>	10000.0	nM	PMID[21090801]
NPT81	Cell line	A549	Homo sapiens	GI50	=	130.0	nM	PMID[21194809]
NPT306	Cell line	PC-3	Homo sapiens	GI50	=	160.0	nM	PMID[21194809]
NPT381	Cell line	OVCAR-8	Homo sapiens	GI50	=	150.0	nM	PMID[21194809]
NPT179	Cell line	A2780	Homo sapiens	GI50	=	180.0	nM	PMID[21194809]
NPT91	Cell line	KB	Homo sapiens	GI50	=	190.0	nM	PMID[21194809]
NPT515	Cell line	SGC-7901	Homo sapiens	IC50	=	0.078	ug.mL-1	PMID[21296573]
NPT515	Cell line	SGC-7901	Homo sapiens	IC50	=	0.078	ug.mL-1	PMID[21247667]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	130.0	nM	PMID[21192108]
NPT81	Cell line	A549	Homo sapiens	IC50	=	410.0	nM	PMID[21192108]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	150.0	nM	PMID[21192108]
NPT407	Cell line	COLO 205	Homo sapiens	GI50	<	100.0	nM	PMID[21402478]
NPT81	Cell line	A549	Homo sapiens	GI50	<	100.0	nM	PMID[21402478]
NPT179	Cell line	A2780	Homo sapiens	GI50	<	100.0	nM	PMID[21402478]
NPT83	Cell line	MCF7	Homo sapiens	GI50	=	130.0	nM	PMID[21402478]
NPT91	Cell line	KB	Homo sapiens	GI50	=	130.0	nM	PMID[21402478]
NPT133	Cell line	ZR-75-1	Homo sapiens	GI50	=	1790.0	nM	PMID[21459581]
NPT81	Cell line	A549	Homo sapiens	GI50	=	7250.0	nM	PMID[21459581]
NPT179	Cell line	A2780	Homo sapiens	GI50	=	160.0	nM	PMID[21459581]
NPT379	Cell line	HOP-62	Homo sapiens	GI50	=	140.0	nM	PMID[21459581]
NPT91	Cell line	KB	Homo sapiens	GI50	=	170.0	nM	PMID[21459581]
NPT2245	Cell line	SiHa	Homo sapiens	GI50	=	170.0	nM	PMID[21459581]
NPT83	Cell line	MCF7	Homo sapiens	GI50	=	170.0	nM	PMID[21459581]
NPT407	Cell line	COLO 205	Homo sapiens	GI50	=	140.0	nM	PMID[21459581]
NPT306	Cell line	PC-3	Homo sapiens	GI50	=	1810.0	nM	PMID[21459581]
NPT91	Cell line	KB	Homo sapiens	IC50	=	270.0	nM	PMID[21473608]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	4900.0	nM	PMID[21473608]
NPT639	Cell line	NCI-H187	Homo sapiens	IC50	=	230.0	nM	PMID[21473608]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1320.0	nM	PMID[21419530]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	6810.0	nM	PMID[21419530]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	2470.0	nM	PMID[21419530]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	840.0	nM	PMID[21419530]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	320.0	nM	PMID[21419530]
NPT82	Cell line	MDA-MB-231	Homo sapiens	GI50	=	90.0	nM	PMID[21718029]
NPT82	Cell line	MDA-MB-231	Homo sapiens	TGI	=	180.0	nM	PMID[21718029]
NPT139	Cell line	HT-29	Homo sapiens	GI50	=	150.0	nM	PMID[21718029]
NPT139	Cell line	HT-29	Homo sapiens	TGI	=	180.0	nM	PMID[21718029]
NPT81	Cell line	A549	Homo sapiens	GI50	=	60.0	nM	PMID[21718029]
NPT81	Cell line	A549	Homo sapiens	TGI	=	200.0	nM	PMID[21718029]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	430.0	nM	PMID[21821321]
NPT111	Cell line	K562	Homo sapiens	IC50	=	360.0	nM	PMID[21821321]
NPT2307	Cell line	769-P	Homo sapiens	IC50	=	11500.0	nM	PMID[21875764]
NPT91	Cell line	KB	Homo sapiens	IC50	=	600.0	nM	PMID[21875764]
NPT547	Cell line	BGC-823	Homo sapiens	IC50	<	1300.0	nM	PMID[21875764]
NPT401	Cell line	786-0	Homo sapiens	IC50	=	3100.0	nM	PMID[21875764]
NPT65	Cell line	HepG2	Homo sapiens	IC50	<	1300.0	nM	PMID[21875764]
NPT1083	Cell line	A-375	Homo sapiens	IC50	=	17200.0	nM	PMID[21875764]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	4200.0	nM	PMID[21875764]
NPT1997	Cell line	OS-RC-2	Homo sapiens	IC50	<	1300.0	nM	PMID[21875764]
NPT1629	Cell line	CWR22R	Homo sapiens	IC50	<	1300.0	nM	PMID[21875764]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	5100.0	nM	PMID[21875764]
NPT1723	Cell line	HBL-100	Homo sapiens	IC50	=	140.0	ug.mL-1	PMID[22142614]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	580.0	ug.mL-1	PMID[22142614]
NPT83	Cell line	MCF7	Homo sapiens	IC50	<	68.0	ug.mL-1	PMID[22142614]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	<	68.0	ug.mL-1	PMID[22142614]
NPT65	Cell line	HepG2	Homo sapiens	IC50	<	68.0	ug.mL-1	PMID[22142614]
NPT2303	Cell line	647-V	Homo sapiens	IC50	<	68.0	ug.mL-1	PMID[22142614]
NPT165	Cell line	HeLa	Homo sapiens	IC50	<	68.0	ug.mL-1	PMID[22142614]
NPT91	Cell line	KB	Homo sapiens	IC50	=	1200.0	nM	PMID[21995505]
NPT639	Cell line	NCI-H187	Homo sapiens	IC50	=	250.0	nM	PMID[21995505]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	15000.0	nM	PMID[21995505]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	1180.0	nM	PMID[22318158]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	3030.0	nM	PMID[22318158]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	1450.0	nM	PMID[22318158]
NPT111	Cell line	K562	Homo sapiens	IC50	=	2350.0	nM	PMID[22318158]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	1090.0	nM	PMID[22318158]
NPT3140	Cell line	MGC-803	Homo sapiens	IC50	=	2560.0	nM	PMID[22318158]
NPT1649	Cell line	MV4-11	Homo sapiens	IC50	=	6.0	nM	PMID[22748378]
NPT81	Cell line	A549	Homo sapiens	IC50	=	329.0	nM	PMID[22748378]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	390.0	nM	PMID[22748378]
NPT2711	Cell line	BALB/3T3	Mus musculus	IC50	=	1078.0	nM	PMID[22748378]
NPT91	Cell line	KB	Homo sapiens	IC50	=	840.0	nM	PMID[22574992]
NPT886	Cell line	NIH3T3	Mus musculus	IC50	=	1080.0	nM	PMID[22574992]
NPT81	Cell line	A549	Homo sapiens	IC50	=	330.0	nM	PMID[22574992]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	440.0	nM	PMID[22574992]
NPT114	Cell line	LoVo	Homo sapiens	IC50	=	110.0	nM	PMID[22574992]
NPT134	Cell line	SK-BR-3	Homo sapiens	GI50	=	65.5	nM	PMID[22607205]
NPT139	Cell line	HT-29	Homo sapiens	GI50	=	153.0	nM	PMID[22607205]
NPT81	Cell line	A549	Homo sapiens	GI50	=	60.3	nM	PMID[22607205]
NPT91	Cell line	KB	Homo sapiens	IC50	=	10.0	nM	PMID[23131338]
NPT1083	Cell line	A-375	Homo sapiens	IC50	=	730.0	nM	PMID[23131338]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	1110.0	nM	PMID[23131338]
NPT547	Cell line	BGC-823	Homo sapiens	IC50	=	10.0	nM	PMID[23131338]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	0.183	%	DOI[10.1007/s00044-011-9688-z]
NPT83	Cell line	MCF7	Homo sapiens	GI50	<	100.0	nM	DOI[10.1007/s00044-011-9688-z]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	-33.5	%	DOI[10.1007/s00044-011-9688-z]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	-23.7	%	DOI[10.1007/s00044-011-9688-z]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	-13.9	%	DOI[10.1007/s00044-011-9688-z]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	53.5	%	DOI[10.1007/s00044-011-9688-z]
NPT116	Cell line	HL-60	Homo sapiens	Ratio IC50	=	100.0	n.a.	DOI[10.1007/s00044-011-9703-4]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	40.0	nM	DOI[10.1007/s00044-011-9703-4]
NPT83	Cell line	MCF7	Homo sapiens	GI	=	77.0	%	DOI[10.1007/s00044-011-9887-7]
NPT399	Cell line	SF-295	Homo sapiens	GI	=	87.0	%	DOI[10.1007/s00044-011-9887-7]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	800.0	nM	DOI[10.1007/s00044-010-9500-5]
NPT744	Cell line	IMR-32	Homo sapiens	IC50	=	20.0	nM	DOI[10.1007/s00044-010-9500-5]
NPT83	Cell line	MCF7	Homo sapiens	GI	=	72.0	%	DOI[10.1007/s00044-010-9410-6]
NPT399	Cell line	SF-295	Homo sapiens	GI	=	69.0	%	DOI[10.1007/s00044-010-9410-6]
NPT458	Cell line	IGROV-1	Homo sapiens	GI	=	39.0	%	DOI[10.1007/s00044-010-9410-6]
NPT379	Cell line	HOP-62	Homo sapiens	GI	=	32.0	%	DOI[10.1007/s00044-010-9410-6]
NPT81	Cell line	A549	Homo sapiens	GI	=	27.0	%	DOI[10.1007/s00044-010-9410-6]
NPT744	Cell line	IMR-32	Homo sapiens	GI	=	82.0	%	DOI[10.1007/s00044-012-0106-y]
NPT81	Cell line	A549	Homo sapiens	GI	=	50.0	%	DOI[10.1007/s00044-012-0106-y]
NPT165	Cell line	HeLa	Homo sapiens	GI	=	58.0	%	DOI[10.1007/s00044-012-0106-y]
NPT323	Cell line	SW-620	Homo sapiens	GI	=	38.0	%	DOI[10.1007/s00044-012-0106-y]
NPT407	Cell line	COLO 205	Homo sapiens	GI	=	89.0	%	DOI[10.1007/s00044-012-0106-y]
NPT112	Cell line	MOLT-4	Homo sapiens	GI50	<	100.0	nM	DOI[10.1007/s00044-012-0423-1]
NPT83	Cell line	MCF7	Homo sapiens	GI50	<	100.0	nM	DOI[10.1007/s00044-012-0423-1]
NPT65	Cell line	HepG2	Homo sapiens	GI50	<	100.0	nM	DOI[10.1007/s00044-012-0423-1]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	2.22	%	DOI[10.1007/s00044-013-0486-7]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	76.76	%	DOI[10.1007/s00044-013-0486-7]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	4.01	%	DOI[10.1007/s00044-013-0486-7]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	16.62	%	DOI[10.1007/s00044-013-0486-7]
NPT400	Cell line	MDA-MB-435	Homo sapiens	IC50	=	0.93	ug.mL-1	DOI[10.1007/s00044-013-0486-7]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	0.81	ug.mL-1	DOI[10.1007/s00044-013-0486-7]
NPT400	Cell line	MDA-MB-435	Homo sapiens	IC50	=	0.77	ug.mL-1	DOI[10.1007/s00044-013-0486-7]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	0.69	ug.mL-1	DOI[10.1007/s00044-013-0486-7]
NPT2711	Cell line	BALB/3T3	Mus musculus	IC50	=	1078.0	nM	DOI[10.1007/s00044-012-0443-x]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	390.0	nM	DOI[10.1007/s00044-012-0443-x]
NPT81	Cell line	A549	Homo sapiens	IC50	=	329.0	nM	DOI[10.1007/s00044-012-0443-x]
NPT1649	Cell line	MV4-11	Homo sapiens	IC50	=	6.0	nM	DOI[10.1007/s00044-012-0443-x]
NPT81	Cell line	A549	Homo sapiens	Activity	=	1.34	%	DOI[10.1007/s00044-013-0520-9]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	61.55	%	DOI[10.1007/s00044-013-0520-9]
NPT81	Cell line	A549	Homo sapiens	Activity	=	0.98	%	DOI[10.1007/s00044-013-0520-9]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	36.19	%	DOI[10.1007/s00044-013-0520-9]
NPT81	Cell line	A549	Homo sapiens	Activity	=	7.13	%	DOI[10.1007/s00044-013-0520-9]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	55.74	%	DOI[10.1007/s00044-013-0520-9]
NPT81	Cell line	A549	Homo sapiens	Activity	=	6.97	%	DOI[10.1007/s00044-013-0520-9]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	30.86	%	DOI[10.1007/s00044-013-0520-9]
NPT407	Cell line	COLO 205	Homo sapiens	GI	=	72.0	%	DOI[10.1007/s00044-012-0312-7]
NPT306	Cell line	PC-3	Homo sapiens	GI	=	66.0	%	DOI[10.1007/s00044-012-0404-4]
NPT407	Cell line	COLO 205	Homo sapiens	GI	=	69.0	%	DOI[10.1007/s00044-012-0404-4]
NPT83	Cell line	MCF7	Homo sapiens	GI	=	72.0	%	DOI[10.1007/s00044-012-0404-4]
NPT382	Cell line	OVCAR-5	Homo sapiens	GI	=	60.0	%	DOI[10.1007/s00044-012-0404-4]
NPT83	Cell line	MCF7	Homo sapiens	GI	=	90.0	%	PMID[23419739]
NPT165	Cell line	HeLa	Homo sapiens	GI50	=	170.0	nM	PMID[23353738]
NPT114	Cell line	LoVo	Homo sapiens	GI50	=	240.0	nM	PMID[23353738]
NPT139	Cell line	HT-29	Homo sapiens	GI50	=	150.0	nM	PMID[23353738]
NPT461	Cell line	PANC-1	Homo sapiens	GI50	=	240.0	nM	PMID[23353738]
NPT111	Cell line	K562	Homo sapiens	GI50	=	170.0	nM	PMID[23353738]
NPT81	Cell line	A549	Homo sapiens	IC50	=	200.0	nM	PMID[23806071]
NPT111	Cell line	K562	Homo sapiens	IC50	=	300.0	nM	PMID[23806071]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	600.0	nM	PMID[23806071]
NPT2351	Cell line	MG-63	Homo sapiens	IC50	=	3400.0	nM	PMID[23477504]
NPT81	Cell line	A549	Homo sapiens	IC50	=	2800.0	nM	PMID[23477504]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	75.0	nM	PMID[24153206]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	390.0	nM	PMID[24153206]
NPT169	Cell line	B16-F10	Mus musculus	GI50	=	0.22	ug.mL-1	PMID[24507920]
NPT398	Cell line	UACC-62	Homo sapiens	GI50	=	0.25	ug.mL-1	PMID[24507920]
NPT83	Cell line	MCF7	Homo sapiens	GI50	=	0.23	ug.mL-1	PMID[24507920]
NPT401	Cell line	786-0	Homo sapiens	GI50	=	0.43	ug.mL-1	PMID[24507920]
NPT1649	Cell line	MV4-11	Homo sapiens	IC50	=	6.0	nM	PMID[24686018]
NPT2711	Cell line	BALB/3T3	Mus musculus	IC50	=	1080.0	nM	PMID[24686018]
NPT81	Cell line	A549	Homo sapiens	IC50	=	330.0	nM	PMID[24686018]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	390.0	nM	PMID[24686018]
NPT2711	Cell line	BALB/3T3	Mus musculus	IC50	=	1080.0	nM	PMID[24686017]
NPT81	Cell line	A549	Homo sapiens	IC50	=	330.0	nM	PMID[24686017]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	440.0	nM	PMID[24686017]
NPT114	Cell line	LoVo	Homo sapiens	IC50	=	110.0	nM	PMID[24686017]
NPT91	Cell line	KB	Homo sapiens	IC50	=	840.0	nM	PMID[24686017]
NPT137	Cell line	L1210	Mus musculus	ED50	=	1.5	uM	PMID[690999]
NPT137	Cell line	L1210	Mus musculus	ED50	=	0.67	uM	PMID[690999]
NPT369	Cell line	ACHN	Homo sapiens	IC50	=	260.0	nM	PMID[25442319]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	600.0	nM	PMID[25442319]
NPT370	Cell line	NCI-H23	Homo sapiens	IC50	=	490.0	nM	PMID[25442319]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	2780.0	nM	PMID[25529734]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	4060.0	nM	PMID[25529734]
NPT71	Cell line	HEK293	Homo sapiens	IC50	=	1220.0	nM	PMID[25062006]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	3890.0	nM	PMID[25062006]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	3120.0	nM	PMID[25062006]
NPT165	Cell line	HeLa	Homo sapiens	IC50	<	100.0	nM	PMID[24951333]
NPT83	Cell line	MCF7	Homo sapiens	IC50	<	100.0	nM	PMID[24951333]
NPT112	Cell line	MOLT-4	Homo sapiens	IC50	=	70.0	nM	PMID[25064348]
NPT404	Cell line	CCRF-CEM	Homo sapiens	IC50	=	150.0	nM	PMID[25064348]
NPT927	Cell line	PBMC	Homo sapiens	Activity	>	80.0	%	PMID[25064348]
NPT1872	Cell line	Bcap37	Homo sapiens	GI	=	96.2	%	PMID[25064351]
NPT3140	Cell line	MGC-803	Homo sapiens	GI	=	95.8	%	PMID[25064351]
NPT3140	Cell line	MGC-803	Homo sapiens	IC50	=	710.0	nM	PMID[25064351]
NPT1872	Cell line	Bcap37	Homo sapiens	IC50	=	940.0	nM	PMID[25064351]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	880.0	nM	PMID[25408835]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	94100.0	nM	PMID[25408835]
NPT1970	Cell line	THP-1	Homo sapiens	GI	=	71.0	%	PMID[25128667]
NPT407	Cell line	COLO 205	Homo sapiens	GI	=	72.0	%	PMID[25128667]
NPT83	Cell line	MCF7	Homo sapiens	Ratio IC50	=	240.9	n.a.	PMID[25208345]
NPT65	Cell line	HepG2	Homo sapiens	Activity	=	61.0	%	PMID[25208345]
NPT81	Cell line	A549	Homo sapiens	IC50	=	100.0	nM	PMID[25259515]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	10100.0	nM	PMID[25304898]
NPT111	Cell line	K562	Homo sapiens	IC50	=	8900.0	nM	PMID[25304898]
NPT81	Cell line	A549	Homo sapiens	IC50	=	4300.0	nM	PMID[25304898]
NPT3891	Cell line	S180	Mus musculus	TGI	=	71.7	%	PMID[25304898]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	21450.0	nM	PMID[25226363]
NPT81	Cell line	A549	Homo sapiens	IC50	=	23710.0	nM	PMID[25226363]
NPT319	Cell line	B16	Mus musculus	IC50	=	6400.0	nM	PMID[25611131]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	720.0	nM	PMID[25739048]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	410.0	nM	PMID[25739048]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	240.0	nM	PMID[25739048]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	1210.0	nM	PMID[26022080]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	410.0	nM	PMID[26022080]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	1020.0	nM	PMID[26022080]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1010.0	nM	PMID[26022080]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	500.0	nM	PMID[26539973]
NPT111	Cell line	K562	Homo sapiens	IC50	=	300.0	nM	PMID[26506221]
NPT2341	Cell line	NCI-H1975	Homo sapiens	IC50	=	800.0	nM	PMID[26506221]
NPT81	Cell line	A549	Homo sapiens	IC50	=	200.0	nM	PMID[26506221]
NPT165	Cell line	HeLa	Homo sapiens	TGI	<	100.0	nM	PMID[26725026]
NPT165	Cell line	HeLa	Homo sapiens	GI50	<	100.0	nM	PMID[26725026]
NPT83	Cell line	MCF7	Homo sapiens	GI50	=	54.0	nM	PMID[26741854]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	2500.0	nM	PMID[26810315]
NPT81	Cell line	A549	Homo sapiens	IC50	=	40.0	nM	DOI[10.1039/C5MD00289C]
NPT111	Cell line	K562	Homo sapiens	IC50	=	59.0	nM	PMID[26832219]
NPT116	Cell line	HL-60	Homo sapiens	Ratio IC50	=	300.0	n.a.	PMID[26832219]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	40.0	nM	PMID[26866967]
NPT396	Cell line	T47D	Homo sapiens	Ratio IC50	=	1.7	n.a.	PMID[26866967]
NPT396	Cell line	T47D	Homo sapiens	Ratio IC50	=	44.0	n.a.	PMID[26866967]
NPT111	Cell line	K562	Homo sapiens	IC50	=	6230.0	nM	PMID[27073052]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	1340.0	nM	PMID[26927425]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	820.0	nM	PMID[26927425]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	1340.0	nM	PMID[26945111]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	880.0	nM	PMID[26945111]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	2900.0	nM	PMID[26988802]
NPT65	Cell line	HepG2	Homo sapiens	Activity	=	238.7	mm3	PMID[26979159]
NPT65	Cell line	HepG2	Homo sapiens	Activity	=	0.188	g	PMID[26979159]
NPT111	Cell line	K562	Homo sapiens	IC50	=	10.0	nM	PMID[28045256]
NPT111	Cell line	K562	Homo sapiens	IC50	=	590.0	nM	PMID[28068095]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1300.0	nM	PMID[28006904]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	9200.0	nM	PMID[28006904]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	5300.0	nM	PMID[28006904]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	1000.0	nM	PMID[28068603]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	300.0	nM	PMID[28068603]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1200.0	nM	PMID[28068603]
NPT165	Cell line	HeLa	Homo sapiens	TGI	<	100.0	nM	PMID[28188067]
NPT165	Cell line	HeLa	Homo sapiens	GI50	<	100.0	nM	PMID[28188067]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	-84.6	%	PMID[28188067]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	-84.1	%	PMID[28188067]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	-82.9	%	PMID[28188067]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	-76.8	%	PMID[28188067]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	19.0	nM	PMID[28068601]
NPT83	Cell line	MCF7	Homo sapiens	GI	<	34.0	%	PMID[27933892]
NPT65	Cell line	HepG2	Homo sapiens	GI	<	34.0	%	PMID[27933892]
NPT15	Cell line	Jurkat	Homo sapiens	GI	<	34.0	%	PMID[27933892]
NPT81	Cell line	A549	Homo sapiens	GI	<	34.0	%	PMID[27933892]
NPT111	Cell line	K562	Homo sapiens	GI	<	34.0	%	PMID[27933892]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	-82.9	%	PMID[27987486]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	-76.8	%	PMID[27987486]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	-84.1	%	PMID[27987486]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	-84.6	%	PMID[27987486]
NPT165	Cell line	HeLa	Homo sapiens	GI50	<	100.0	nM	PMID[27987486]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	500.0	nM	PMID[27992183]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	200.0	nM	PMID[27992183]
NPT1374	Cell line	WI-38	Homo sapiens	IC50	=	80.0	nM	PMID[27997206]
NPT83	Cell line	MCF7	Homo sapiens	GI50	<	100.0	nM	PMID[28258796]
NPT83	Cell line	MCF7	Homo sapiens	TGI	=	11000.0	nM	PMID[28258796]
NPT189	Cell line	Vero	Chlorocebus aethiops	TGI	>	10000.0	nM	PMID[28258796]
NPT189	Cell line	Vero	Chlorocebus aethiops	GI50	=	19000.0	nM	PMID[28258796]
NPT306	Cell line	PC-3	Homo sapiens	Activity	<	90.0	%	PMID[28177244]
NPT82	Cell line	MDA-MB-231	Homo sapiens	Activity	<	90.0	%	PMID[28177244]
NPT845	Cell line	BT-474	Homo sapiens	Activity	<	90.0	%	PMID[28177244]
NPT90	Cell line	DU-145	Homo sapiens	Activity	<	90.0	%	PMID[28177244]
NPT783	Cell line	MIA PaCa-2	Homo sapiens	Activity	<	90.0	%	PMID[28177244]
NPT845	Cell line	BT-474	Homo sapiens	Activity	=	75.0	%	PMID[28177244]
NPT845	Cell line	BT-474	Homo sapiens	Activity	=	72.0	%	PMID[28177244]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	16890.0	nM	PMID[28222318]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	1760.0	nM	PMID[28222318]
NPT111	Cell line	K562	Homo sapiens	IC50	=	570.0	nM	PMID[28222318]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1230.0	nM	PMID[28222318]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	1280.0	nM	PMID[28384547]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	250.0	nM	PMID[28384547]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1200.0	nM	PMID[28384547]
NPT1229	Cell line	Huh-7	Homo sapiens	IC50	=	14800.0	nM	PMID[27704808]
NPT81	Cell line	A549	Homo sapiens	IC50	=	2900.0	nM	PMID[27704808]
NPT2351	Cell line	MG-63	Homo sapiens	IC50	=	2200.0	nM	PMID[27704808]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	990.0	nM	PMID[28720329]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	3.9	%	PMID[28720329]
NPT189	Cell line	Vero	Chlorocebus aethiops	GI50	=	20.0	nM	PMID[28778369]
NPT189	Cell line	Vero	Chlorocebus aethiops	GI50	=	2000.0	nM	PMID[28778369]
NPT111	Cell line	K562	Homo sapiens	IC50	=	510.0	nM	PMID[28301155]
NPT111	Cell line	K562	Homo sapiens	Ratio IC50	=	105.8	n.a.	PMID[28301155]
NPT111	Cell line	K562	Homo sapiens	IC50	=	77.7	nM	PMID[28333459]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	940.0	nM	PMID[28633898]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	1290.0	nM	PMID[28633898]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	2770.0	nM	PMID[28633898]
NPT111	Cell line	K562	Homo sapiens	IC50	=	4290.0	nM	PMID[28645831]
NPT1171	Cell line	HEp-2	Homo sapiens	IC50	<	1000.0	nM	PMID[28757067]
NPT83	Cell line	MCF7	Homo sapiens	IC50	<	1000.0	nM	PMID[28757067]
NPT547	Cell line	BGC-823	Homo sapiens	IC50	<	1000.0	nM	PMID[28757067]
NPT180	Cell line	HCT-8	Homo sapiens	IC50	<	1000.0	nM	PMID[28757067]
NPT65	Cell line	HepG2	Homo sapiens	IC50	<	1000.0	nM	PMID[28757067]
NPT165	Cell line	HeLa	Homo sapiens	IC50	<	1000.0	nM	PMID[28757067]
NPT306	Cell line	PC-3	Homo sapiens	IC50	<	1000.0	nM	PMID[28757067]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	600.0	nM	PMID[28418245]
NPT2678	Cell line	NB-4	Homo sapiens	IC50	=	400.0	nM	PMID[28418245]
NPT81	Cell line	A549	Homo sapiens	IC50	=	200.0	nM	PMID[28418245]
NPT2341	Cell line	NCI-H1975	Homo sapiens	IC50	=	200.0	nM	PMID[28418245]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	20.0	nM	PMID[28418245]
NPT111	Cell line	K562	Homo sapiens	IC50	=	300.0	nM	PMID[28418245]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	200.0	nM	PMID[28418245]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	300.0	nM	PMID[28445049]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	1200.0	nM	PMID[28445049]
NPT81	Cell line	A549	Homo sapiens	IC50	=	500.0	nM	PMID[28445049]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	4600.0	nM	PMID[29884536]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1400.0	nM	PMID[29884536]
NPT1460	Cell line	L929	Mus musculus	IC50	=	7500.0	nM	PMID[29884536]
NPT81	Cell line	A549	Homo sapiens	IC50	=	8500.0	nM	PMID[29884536]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1720.0	nM	PMID[29903663]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	50740.0	nM	PMID[29903663]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	2190.0	nM	PMID[29903663]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	44.8	nM	PMID[28763646]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	54750.0	nM	PMID[28763646]
NPT81	Cell line	A549	Homo sapiens	IC50	=	481.0	nM	PMID[29182349]
NPT91	Cell line	KB	Homo sapiens	IC50	=	570.0	nM	PMID[29182349]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	76.0	nM	PMID[29182349]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	559.0	nM	PMID[29182349]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	700.0	nM	PMID[29215886]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	420.0	nM	PMID[29215886]
NPT659	Cell line	SMMC-7721	Homo sapiens	IC50	=	660.0	nM	PMID[29215886]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	3000.0	nM	PMID[29286660]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	100.0	nM	PMID[29286660]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	2900.0	nM	PMID[29286660]
NPT81	Cell line	A549	Homo sapiens	IC50	=	1300.0	nM	PMID[29286660]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	20.0	nM	PMID[29286660]
NPT2257	Cell line	MCF-10A	Homo sapiens	IC50	=	200.0	nM	PMID[29286660]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1200.0	nM	PMID[28803046]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	1800.0	nM	PMID[28803046]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	82.5	%	PMID[28803046]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	16.2	%	PMID[28803046]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	1.2	%	PMID[28803046]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	59.1	%	PMID[28803046]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	40.1	%	PMID[28803046]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	0.8	%	PMID[28803046]
NPT111	Cell line	K562	Homo sapiens	IC50	=	390.0	nM	PMID[29335204]
NPT369	Cell line	ACHN	Homo sapiens	GI50	=	70.0	nM	PMID[29878761]
NPT148	Cell line	HCT-15	Homo sapiens	GI50	=	50.0	nM	PMID[29878761]
NPT82	Cell line	MDA-MB-231	Homo sapiens	GI50	=	70.0	nM	PMID[29878761]
NPT370	Cell line	NCI-H23	Homo sapiens	GI50	=	80.0	nM	PMID[29878761]
NPT2477	Cell line	NUGC-3	Homo sapiens	GI50	=	70.0	nM	PMID[29878761]
NPT306	Cell line	PC-3	Homo sapiens	GI50	=	90.0	nM	PMID[29878761]
NPT111	Cell line	K562	Homo sapiens	IC50	=	300.0	nM	PMID[29985604]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	200.0	nM	PMID[29985604]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	200.0	nM	PMID[29985604]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	1000.0	nM	PMID[29985604]
NPT519	Cell line	SH-SY5Y	Homo sapiens	IC50	=	100.0	nM	PMID[29985604]
NPT3140	Cell line	MGC-803	Homo sapiens	IC50	=	200.0	nM	PMID[29985604]
NPT461	Cell line	PANC-1	Homo sapiens	IC50	=	1700.0	nM	PMID[29656202]
NPT461	Cell line	PANC-1	Homo sapiens	IC50	=	480.0	nM	PMID[29656202]
NPT461	Cell line	PANC-1	Homo sapiens	Ratio IC50	=	0.29	n.a.	PMID[29656202]
NPT2297	Cell line	ASPC1	Homo sapiens	IC50	=	1600.0	nM	PMID[29656202]
NPT2297	Cell line	ASPC1	Homo sapiens	IC50	=	2000.0	nM	PMID[29656202]
NPT2297	Cell line	ASPC1	Homo sapiens	Ratio IC50	=	0.78	n.a.	PMID[29656202]
NPT461	Cell line	PANC-1	Homo sapiens	Activity	=	8.9	%	PMID[29656202]
NPT461	Cell line	PANC-1	Homo sapiens	FC	=	1.6	n.a.	PMID[29656202]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	44.82	nM	PMID[29754076]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	54749.19	nM	PMID[29754076]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	510.0	nM	PMID[30262132]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	310.0	nM	PMID[30262132]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1500.0	nM	PMID[30262132]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	510.0	nM	PMID[29402741]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	310.0	nM	PMID[29402741]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1500.0	nM	PMID[29402741]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	300.0	nM	PMID[28749671]
NPT81	Cell line	A549	Homo sapiens	IC50	=	100.0	nM	PMID[28749671]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	200.0	nM	PMID[28749671]
NPT81	Cell line	A549	Homo sapiens	IC50	=	160.0	nM	PMID[29407953]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	600.0	nM	PMID[29407953]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	36.0	nM	PMID[29407953]
NPT81	Cell line	A549	Homo sapiens	IC50	=	1300.0	nM	PMID[30137985]
NPT179	Cell line	A2780	Homo sapiens	IC50	=	500.0	nM	PMID[30137985]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	310.0	nM	PMID[30222343]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1000.0	nM	PMID[30222343]
NPT81	Cell line	A549	Homo sapiens	IC50	=	120.0	nM	PMID[30222343]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	730.0	nM	PMID[29510948]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	840.0	nM	PMID[29510948]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1700.0	nM	PMID[29510948]
NPT111	Cell line	K562	Homo sapiens	IC50	=	970.0	nM	PMID[29631786]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	400.0	nM	PMID[30049584]
NPT81	Cell line	A549	Homo sapiens	IC50	=	100.0	nM	PMID[30049584]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	800.0	nM	PMID[30049584]
NPT81	Cell line	A549	Homo sapiens	IC50	=	1450.0	nM	PMID[28570977]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	2300.0	nM	PMID[28570977]
NPT111	Cell line	K562	Homo sapiens	IC50	=	610.0	nM	PMID[28570977]
NPT82	Cell line	MDA-MB-231	Homo sapiens	GI50	=	120.0	nM	PMID[29102180]
NPT83	Cell line	MCF7	Homo sapiens	GI50	=	54.0	nM	PMID[29102180]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	GI50	=	540.0	nM	PMID[29102180]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	3760.0	nM	PMID[29174815]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	4880.0	nM	PMID[29174815]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	840.0	nM	PMID[29174815]
NPT2257	Cell line	MCF-10A	Homo sapiens	IC50	=	930.0	nM	PMID[29174815]
NPT659	Cell line	SMMC-7721	Homo sapiens	IC50	=	2670.0	nM	PMID[29232583]
NPT515	Cell line	SGC-7901	Homo sapiens	IC50	=	4120.0	nM	PMID[29232583]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	2310.0	nM	PMID[29232583]
NPT659	Cell line	SMMC-7721	Homo sapiens	Inhibition	=	80.0	%	PMID[29232583]
NPT659	Cell line	SMMC-7721	Homo sapiens	Activity	=	47.5	%	PMID[29232583]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	100.0	nM	PMID[29489361]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	100.0	nM	PMID[29489361]
NPT81	Cell line	A549	Homo sapiens	IC50	=	2.0	nM	PMID[29489361]
NPT116	Cell line	HL-60	Homo sapiens	GI50	=	20.0	nM	PMID[29565129]
NPT111	Cell line	K562	Homo sapiens	GI50	=	20.0	nM	PMID[29565129]
NPT461	Cell line	PANC-1	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT1081	Cell line	BXPC-3	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT306	Cell line	PC-3	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT139	Cell line	HT-29	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT660	Cell line	SW480	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT111	Cell line	K562	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT116	Cell line	HL-60	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT2341	Cell line	NCI-H1975	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT65	Cell line	HepG2	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT393	Cell line	HCT-116	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT83	Cell line	MCF7	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT165	Cell line	HeLa	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT81	Cell line	A549	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT547	Cell line	BGC-823	Homo sapiens	IC50	=	1500.0	nM	PMID[28206772]
NPT397	Cell line	NCI-H460	Homo sapiens	IC50	=	1000.0	nM	PMID[28206772]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	1400.0	nM	PMID[28206772]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1000.0	nM	PMID[28206772]
NPT659	Cell line	SMMC-7721	Homo sapiens	IC50	=	2200.0	nM	PMID[28206772]
NPT1317	Cell line	CCRF S-180	Mus musculus	TGI	=	61.1	%	PMID[28583770]
NPT181	Cell line	Bel-7402	Homo sapiens	IC50	=	730.0	nM	PMID[30006167]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	410.0	nM	PMID[30006167]
NPT461	Cell line	PANC-1	Homo sapiens	IC50	=	2110.0	nM	PMID[30006167]
NPT81	Cell line	A549	Homo sapiens	IC50	=	140.0	nM	PMID[30006167]
NPT1535	Cell line	U-87 MG	Homo sapiens	IC50	=	160.0	nM	PMID[30006167]
NPT886	Cell line	NIH3T3	Mus musculus	IC50	=	550.0	nM	PMID[30006167]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	540.0	nM	PMID[30223117]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	210.0	nM	PMID[30223117]
NPT1535	Cell line	U-87 MG	Homo sapiens	IC50	=	110.0	nM	PMID[30223117]
NPT886	Cell line	NIH3T3	Mus musculus	Activity	=	15.57	%	PMID[30223117]
NPT886	Cell line	NIH3T3	Mus musculus	Activity	=	6.73	%	PMID[30223117]
NPT181	Cell line	Bel-7402	Homo sapiens	IC50	=	730.0	nM	PMID[31553932]
NPT886	Cell line	NIH3T3	Mus musculus	IC50	=	360.0	nM	PMID[30739826]
NPT3722	Cell line	4T1	Mus musculus	IC50	=	800.0	nM	PMID[30739826]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	800.0	nM	PMID[30739826]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	670.0	nM	PMID[30837097]
NPT81	Cell line	A549	Homo sapiens	IC50	=	1130.0	nM	PMID[30837097]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	850.0	nM	PMID[30837097]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	2940.0	nM	PMID[30837097]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	2600.0	nM	PMID[31013087]
NPT659	Cell line	SMMC-7721	Homo sapiens	IC50	=	1100.0	nM	PMID[31013087]
NPT4611	Cell line	PLC-PRF-5	Homo sapiens	IC50	=	1900.0	nM	PMID[31013087]
NPT81	Cell line	A549	Homo sapiens	IC50	<	1000.0	nM	PMID[31804070]
NPT65	Cell line	HepG2	Homo sapiens	IC50	<	1000.0	nM	PMID[31804070]
NPT83	Cell line	MCF7	Homo sapiens	IC50	<	1000.0	nM	PMID[31804070]
NPT2410	Cell line	NCI-H1299	Homo sapiens	IC50	=	800.0	nM	PMID[31268321]
NPT81	Cell line	A549	Homo sapiens	IC50	=	1800.0	nM	PMID[31268321]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	1500.0	nM	PMID[31268321]
NPT659	Cell line	SMMC-7721	Homo sapiens	IC50	=	800.0	nM	PMID[31268321]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1000.0	nM	PMID[31268321]
NPT380	Cell line	U-251	Homo sapiens	IC50	=	2800.0	nM	PMID[31268321]
NPT323	Cell line	SW-620	Homo sapiens	IC50	=	1200.0	nM	PMID[31268321]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	3800.0	nM	PMID[31268321]
NPT91	Cell line	KB	Homo sapiens	IC50	=	3200.0	nM	PMID[31268321]
NPT111	Cell line	K562	Homo sapiens	IC50	=	300.0	nM	PMID[31904949]
NPT1535	Cell line	U-87 MG	Homo sapiens	IC50	=	100.0	nM	PMID[31904949]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	600.0	nM	PMID[31904949]
NPT519	Cell line	SH-SY5Y	Homo sapiens	IC50	=	100.0	nM	PMID[31904949]
NPT81	Cell line	A549	Homo sapiens	IC50	=	200.0	nM	PMID[31904949]
NPT181	Cell line	Bel-7402	Homo sapiens	IC50	=	400.0	nM	PMID[31904949]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	200.0	nM	PMID[31904949]
NPT3140	Cell line	MGC-803	Homo sapiens	IC50	=	200.0	nM	PMID[31904949]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	20.0	nM	PMID[31904949]
NPT3140	Cell line	MGC-803	Homo sapiens	IC50	=	740.0	nM	PMID[31129455]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	1010.0	nM	PMID[31129455]
NPT1872	Cell line	Bcap37	Homo sapiens	IC50	=	1900.0	nM	PMID[31129455]
NPT405	Cell line	NCI-H226	Homo sapiens	IC50	=	300.0	nM	PMID[31397570]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	300.0	nM	PMID[31397570]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	740.0	nM	PMID[31398033]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	340.0	nM	PMID[31398033]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	870.0	nM	PMID[31398033]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	800.0	nM	PMID[31398033]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	5180.0	nM	PMID[31398033]
NPT2459	Cell line	HCC70	Homo sapiens	IC50	=	1450.0	nM	PMID[31398033]
NPT1535	Cell line	U-87 MG	Homo sapiens	IC50	=	150.0	nM	PMID[31977207]
NPT2363	Cell line	U-118-MG	Homo sapiens	IC50	=	90.0	nM	PMID[31977207]
NPT2111	Cell line	SF-126	Homo sapiens	IC50	=	260.0	nM	PMID[31977207]
NPT380	Cell line	U-251	Homo sapiens	IC50	=	48000.0	nM	PMID[31977207]
NPT76	Cell line	C6	Rattus norvegicus	IC50	=	60.0	nM	PMID[31977207]
NPT886	Cell line	NIH3T3	Mus musculus	IC50	=	340.0	nM	PMID[31977207]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	3800.0	nM	PMID[31117521]
NPT81	Cell line	A549	Homo sapiens	IC50	=	2900.0	nM	PMID[31117521]
NPT380	Cell line	U-251	Homo sapiens	IC50	=	2900.0	nM	PMID[31117521]
NPT1535	Cell line	U-87 MG	Homo sapiens	IC50	=	1100.0	nM	PMID[31117521]
NPT659	Cell line	SMMC-7721	Homo sapiens	IC50	=	800.0	nM	PMID[31117521]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	1900.0	nM	PMID[31117521]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	80.0	nM	PMID[31117522]
NPT81	Cell line	A549	Homo sapiens	IC50	=	400.0	nM	PMID[31117522]
NPT81	Cell line	A549	Homo sapiens	IC50	=	440.0	nM	PMID[31184894]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	75.0	nM	PMID[31184894]
NPT83	Cell line	MCF7	Homo sapiens	GI50	=	0.18	nM	PMID[31330449]
NPT181	Cell line	Bel-7402	Homo sapiens	IC50	=	274.0	nM	PMID[30530194]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	60.0	nM	PMID[31436991]
NPT148	Cell line	HCT-15	Homo sapiens	GI50	=	140.0	nM	PMID[31668073]
NPT2477	Cell line	NUGC-3	Homo sapiens	GI50	=	150.0	nM	PMID[31668073]
NPT370	Cell line	NCI-H23	Homo sapiens	GI50	=	140.0	nM	PMID[31668073]
NPT369	Cell line	ACHN	Homo sapiens	GI50	=	130.0	nM	PMID[31668073]
NPT306	Cell line	PC-3	Homo sapiens	GI50	=	140.0	nM	PMID[31668073]
NPT82	Cell line	MDA-MB-231	Homo sapiens	GI50	=	150.0	nM	PMID[31668073]
NPT547	Cell line	BGC-823	Homo sapiens	IC50	=	1480.0	nM	PMID[26933756]
NPT492	Cell line	Caco-2	Homo sapiens	IC50	=	970.0	nM	PMID[26933756]
NPT397	Cell line	NCI-H460	Homo sapiens	IC50	=	980.0	nM	PMID[26933756]
NPT659	Cell line	SMMC-7721	Homo sapiens	IC50	=	2240.0	nM	PMID[26933756]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	22.2	nM	PMID[27213819]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	8153.0	nM	PMID[27213819]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	TGI	=	33.3	%	PMID[27213819]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	670.0	nM	PMID[28818459]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	4.43	%	PMID[27499368]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	8.53	%	PMID[27499368]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	39.22	%	PMID[27499368]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	3.41	%	PMID[27499368]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	44.03	%	PMID[27499368]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	38.42	%	PMID[27499368]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	33.99	%	PMID[27499368]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	27.5	%	PMID[27499368]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	24.02	%	PMID[27499368]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	0.95	%	PMID[27499368]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	1.55	%	PMID[27499368]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	58.5	%	PMID[27499368]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	40.4	%	PMID[27499368]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	46.04	%	PMID[27499368]
NPT165	Cell line	HeLa	Homo sapiens	Activity	=	62.81	%	PMID[27499368]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	66.4	%	PMID[27499368]
NPT111	Cell line	K562	Homo sapiens	Ratio IC50	=	85.36	n.a.	PMID[27503681]
NPT111	Cell line	K562	Homo sapiens	IC50	=	220.0	nM	PMID[27503681]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	420.0	nM	PMID[30677614]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	39520.0	nM	PMID[30677614]
NPT81	Cell line	A549	Homo sapiens	IC50	=	1650.0	nM	PMID[30677614]
NPT81	Cell line	A549	Homo sapiens	IC50	=	700.0	nM	PMID[32293887]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	500.0	nM	PMID[32293887]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	1200.0	nM	PMID[32293887]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	660.0	nM	PMID[32527548]
NPT81	Cell line	A549	Homo sapiens	IC50	=	780.0	nM	PMID[32527548]
NPT492	Cell line	Caco-2	Homo sapiens	IC50	=	720.0	nM	PMID[32527548]
NPT83	Cell line	MCF7	Homo sapiens	GI50	=	170000.0	nM	PMID[32631569]
NPT379	Cell line	HOP-62	Homo sapiens	GI50	=	140000.0	nM	PMID[32631569]
NPT81	Cell line	A549	Homo sapiens	GI50	=	7250000.0	nM	PMID[32631569]
NPT81	Cell line	A549	Homo sapiens	IC50	=	5000.0	nM	PMID[32394716]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	2500.0	nM	PMID[32394716]
NPT91	Cell line	KB	Homo sapiens	IC50	=	2200.0	nM	PMID[32394716]
NPT1535	Cell line	U-87 MG	Homo sapiens	IC50	=	4280.0	nM	PMID[30739827]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	2320.0	nM	PMID[30739827]
NPT659	Cell line	SMMC-7721	Homo sapiens	IC50	=	2670.0	nM	PMID[30739827]
NPT111	Cell line	K562	Homo sapiens	IC50	=	630.0	nM	PMID[30827866]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	140.0	nM	PMID[30827866]
NPT71	Cell line	HEK293	Homo sapiens	IC50	=	370.0	nM	PMID[30827866]
NPT111	Cell line	K562	Homo sapiens	IC50	=	77.7	nM	PMID[31171403]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	100.0	nM	PMID[32840364]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	200.0	nM	PMID[32840364]
NPT2297	Cell line	ASPC1	Homo sapiens	IC50	=	200.0	nM	PMID[32840364]
NPT1535	Cell line	U-87 MG	Homo sapiens	IC50	=	200.0	nM	PMID[32840364]
NPT181	Cell line	Bel-7402	Homo sapiens	IC50	=	300.0	nM	PMID[32840364]
NPT519	Cell line	SH-SY5Y	Homo sapiens	IC50	=	500.0	nM	PMID[32840364]
NPT111	Cell line	K562	Homo sapiens	IC50	=	300.0	nM	PMID[32840364]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	200.0	nM	PMID[32840364]
NPT168	Cell line	P388	Mus musculus	IC50	=	300.0	nM	PMID[33301677]
NPT81	Cell line	A549	Homo sapiens	IC50	=	2300.0	nM	PMID[33301677]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	1800.0	nM	PMID[33301677]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	200.0	nM	PMID[32880456]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	600.0	nM	PMID[32880456]
NPT111	Cell line	K562	Homo sapiens	IC50	=	200.0	nM	PMID[32880456]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	20.0	nM	PMID[32880456]
NPT323	Cell line	SW-620	Homo sapiens	IC50	=	90.0	nM	PMID[32916298]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	90.0	nM	PMID[32916298]
NPT370	Cell line	NCI-H23	Homo sapiens	IC50	=	90.0	nM	PMID[32916298]
NPT111	Cell line	K562	Homo sapiens	IC50	=	830.0	nM	PMID[33132117]
NPT111	Cell line	K562	Homo sapiens	IC50	=	740.0	nM	PMID[33097300]
NPT81	Cell line	A549	Homo sapiens	IC50	=	1700.0	nM	PMID[33097300]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1100.0	nM	PMID[33097300]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	1600.0	nM	PMID[33097300]
NPT737	Cell line	HUVEC	Homo sapiens	IC50	=	4300.0	nM	PMID[33097300]
NPT181	Cell line	Bel-7402	Homo sapiens	IC50	=	830.0	nM	PMID[27158140]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	3600.0	nM	PMID[27707625]
NPT784	Cell line	MDA-MB-468	Homo sapiens	IC50	=	2150.0	nM	PMID[27707625]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	2180.0	nM	PMID[27707625]
NPT139	Cell line	HT-29	Homo sapiens	IC50	=	2600.0	nM	PMID[34176266]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	800.0	nM	PMID[37947788]
NPT81	Cell line	A549	Homo sapiens	IC50	=	700.0	nM	PMID[37947788]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	160.0	nM	PMID[34165979]
NPT2297	Cell line	ASPC1	Homo sapiens	IC50	=	200.0	nM	PMID[35993848]
NPT2477	Cell line	NUGC-3	Homo sapiens	IC50	=	150.0	nM	PMID[35302779]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	400.0	nM	PMID[34176266]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	3200.0	nM	PMID[33913326]
NPT81	Cell line	A549	Homo sapiens	IC50	=	200.0	nM	PMID[36583957]
NPT82	Cell line	MDA-MB-231	Homo sapiens	GI50	=	80.0	nM	PMID[36040099]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	400.0	nM	PMID[34797067]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	200.0	nM	PMID[34282909]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	400.0	nM	PMID[35762988]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	200.0	nM	PMID[35380848]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	2900.0	nM	PMID[34176266]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	300.0	nM	PMID[35993848]
NPT369	Cell line	ACHN	Homo sapiens	GI50	=	70.0	nM	PMID[36040099]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	400.0	nM	PMID[35762988]
NPT306	Cell line	PC-3	Homo sapiens	GI50	=	90.0	nM	PMID[36040099]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	200.0	nM	PMID[34282909]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	150.0	nM	PMID[35302779]
NPT370	Cell line	NCI-H23	Homo sapiens	IC50	=	160.0	nM	PMID[35302779]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	19.0	nM	PMID[36583957]
NPT370	Cell line	NCI-H23	Homo sapiens	GI50	=	80.0	nM	PMID[36040099]
NPT461	Cell line	PANC-1	Homo sapiens	IC50	=	900.0	nM	PMID[35380848]
NPT81	Cell line	A549	Homo sapiens	IC50	=	690.0	nM	PMID[34081476]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1020.0	nM	PMID[34081476]
NPT937	Cell line	NCI-H446	Homo sapiens	IC50	=	1700.0	nM	PMID[34797067]
NPT81	Cell line	A549	Homo sapiens	IC50	=	200.0	nM	PMID[34282909]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	400.0	nM	PMID[33913326]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	800.0	nM	PMID[34081476]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	100.0	nM	PMID[35762988]
NPT148	Cell line	HCT-15	Homo sapiens	GI50	=	90.0	nM	PMID[36040099]
NPT1649	Cell line	MV4-11	Homo sapiens	IC50	=	140.0	nM	PMID[33356258]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	310.0	nM	PMID[34081476]
NPT111	Cell line	K562	Homo sapiens	IC50	=	300.0	nM	PMID[35993848]
NPT783	Cell line	MIA PaCa-2	Homo sapiens	IC50	=	250.0	nM	PMID[36583957]
NPT2444	Cell line	YAPC	Homo sapiens	IC50	=	310.0	nM	PMID[36583957]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	160.0	nM	PMID[35302779]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	180.0	nM	PMID[34165979]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	500.0	nM	PMID[38381613]
NPT81	Cell line	A549	Homo sapiens	IC50	=	900.0	nM	PMID[34176266]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	300.0	nM	PMID[37947788]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1300.0	nM	PMID[34176266]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	20.0	nM	PMID[34762434]
NPT2297	Cell line	ASPC1	Homo sapiens	IC50	=	300.0	nM	PMID[35380848]
NPT2477	Cell line	NUGC-3	Homo sapiens	GI50	=	80.0	nM	PMID[36040099]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	200.0	nM	PMID[34282909]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1200.0	nM	PMID[34176266]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1000.0	nM	PMID[37947788]
NPT369	Cell line	ACHN	Homo sapiens	IC50	=	170.0	nM	PMID[35302779]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	170.0	nM	PMID[35302779]
NPT81	Cell line	A549	Homo sapiens	IC50	=	850.0	nM	PMID[34762434]
NPT81	Cell line	A549	Homo sapiens	IC50	=	1200.0	nM	PMID[34797067]
NPT81	Cell line	A549	Homo sapiens	IC50	=	290.0	nM	PMID[34165979]
NPT2331	Cell line	A-427	Homo sapiens	IC50	=	1300.0	nM	PMID[34176266]
NPT81	Cell line	A549	Homo sapiens	IC50	=	1200.0	nM	PMID[33913326]
NPT2410	Cell line	NCI-H1299	Homo sapiens	IC50	=	4700.0	nM	PMID[33913326]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	0.45	nM	PMID[35152092]
NPT400	Cell line	MDA-MB-435	Homo sapiens	TGI	=	5.5	%	PMID[35694689]
NPT180	Cell line	HCT-8	Homo sapiens	IC50	n.a.	n.a.	n.a.	PMID[33676300]
NPT181	Cell line	Bel-7402	Homo sapiens	IC50	=	274.0	nM	PMID[33676300]
NPT784	Cell line	MDA-MB-468	Homo sapiens	Activity	=	83.0	%	PMID[26994845]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	10.5	%	PMID[26994845]
NPT400	Cell line	MDA-MB-435	Homo sapiens	TGI	=	43400.0	nM	PMID[26994845]
NPT83	Cell line	MCF7	Homo sapiens	GI50	=	50200.0	nM	PMID[32791404]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	1890.0	nM	PMID[34597897]
NPT323	Cell line	SW-620	Homo sapiens	IC50	<	5000.0	nM	PMID[35586422]
NPT81	Cell line	A549	Homo sapiens	IC50	=	150.0	nM	PMID[35931243]
NPT168	Cell line	P388	Mus musculus	IC50	=	1.14	10^-5 uM	PMID[33940466]
NPT83	Cell line	MCF7	Homo sapiens	TGI	=	90400.0	nM	PMID[26994845]
NPT784	Cell line	MDA-MB-468	Homo sapiens	Activity	=	64.5	%	PMID[26994845]
NPT2257	Cell line	MCF-10A	Homo sapiens	IC50	=	860.0	nM	PMID[34992039]
NPT81	Cell line	A549	Homo sapiens	IC50	=	400.0	nM	PMID[35121401]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	602.0	nM	PMID[35152092]
NPT1535	Cell line	U-87 MG	Homo sapiens	IC50	=	570.0	nM	PMID[35367708]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	85140.0	nM	PMID[35339100]
NPT111	Cell line	K562	Homo sapiens	IC50	=	1.0	nM	PMID[36708676]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	200.0	nM	PMID[37593579]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	28400.0	nM	PMID[34649064]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	1290.0	nM	PMID[36493620]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	5560.0	nM	PMID[36493620]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	5850.0	nM	PMID[35123005]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	480.0	nM	PMID[32485531]
NPT65	Cell line	HepG2	Homo sapiens	Inhibition	n.a.	n.a.	%	PMID[34237623]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	2210.0	nM	PMID[34237623]
NPT179	Cell line	A2780	Homo sapiens	IC50	=	2030.0	nM	PMID[35282680]
NPT3722	Cell line	4T1	Mus musculus	TGI	=	90.0	%	PMID[36781147]
NPT405	Cell line	NCI-H226	Homo sapiens	TGI	=	43200.0	nM	PMID[26994845]
NPT784	Cell line	MDA-MB-468	Homo sapiens	Activity	=	22.0	%	PMID[26994845]
NPT91	Cell line	KB	Homo sapiens	IC50	n.a.	n.a.	n.a.	PMID[34794817]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	1480.0	nM	PMID[34678573]
NPT784	Cell line	MDA-MB-468	Homo sapiens	TGI	=	50400.0	nM	PMID[26994845]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	1.0	nM	PMID[33940466]
NPT171	Cell line	MRC5	Homo sapiens	IC50	=	1.54	ug.mL-1	PMID[38229749]
NPT396	Cell line	T47D	Homo sapiens	IC50	=	4590.0	nM	PMID[35123005]
NPT81	Cell line	A549	Homo sapiens	IC50	=	2360.0	nM	PMID[32485531]
NPT137	Cell line	L1210	Mus musculus	ED50	=	0.016	ug ml-1	PMID[35367708]
NPT306	Cell line	PC-3	Homo sapiens	TGI	=	76.7	%	PMID[35694689]
NPT81	Cell line	A549	Homo sapiens	Ratio IC50	=	12.14	n.a.	PMID[35282680]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	190.0	nM	PMID[33774342]
NPT2870	Cell line	Sarcoma-180	Mus musculus	TGI	=	315.0	%	PMID[35367708]
NPT405	Cell line	NCI-H226	Homo sapiens	Activity	=	12.7	%	PMID[26994845]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	232500.0	nM	PMID[34649064]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	5040.0	nM	PMID[35123005]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	25.6	nM	PMID[35084853]
NPT660	Cell line	SW480	Homo sapiens	IC50	=	120.0	nM	PMID[38253024]
NPT179	Cell line	A2780	Homo sapiens	IC50	=	2690.0	nM	PMID[35282680]
NPT377	Cell line	OVCAR-3	Homo sapiens	GI50	<	100.0	nM	PMID[35694689]
NPT377	Cell line	OVCAR-3	Homo sapiens	TGI	=	56.3	%	PMID[35694689]
NPT2192	Cell line	HEL	Homo sapiens	IC50	=	240.0	nM	PMID[38253024]
NPT81	Cell line	A549	Homo sapiens	ED50	=	1.01	ug ml-1	PMID[35367708]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	>	1250.0	nM	PMID[35586422]
NPT81	Cell line	A549	Homo sapiens	IC50	=	310.0	nM	PMID[33333398]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	n.a.	n.a.	n.a.	PMID[34237623]
NPT111	Cell line	K562	Homo sapiens	IC50	n.a.	n.a.	n.a.	PMID[33676300]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	3430.0	nM	PMID[38389893]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	25900.0	nM	PMID[32688198]
NPT111	Cell line	K562	Homo sapiens	Activity	n.a.	n.a.	n.a.	PMID[36780419]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	380.0	nM	PMID[35121401]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	500.0	nM	PMID[38253024]
NPT393	Cell line	HCT-116	Homo sapiens	IC50	=	1.2	nM	PMID[33940466]
NPT405	Cell line	NCI-H226	Homo sapiens	Activity	=	8.1	%	PMID[26994845]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1070.0	nM	PMID[35931243]
NPT453	Cell line	HT-1080	Homo sapiens	IC50	=	8.0	nM	PMID[33774342]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1130.0	nM	PMID[35390712]
NPT137	Cell line	L1210	Mus musculus	ED50	=	0.07	ug ml-1	PMID[35367708]
NPT2297	Cell line	ASPC1	Homo sapiens	IC50	<	5000.0	nM	PMID[35586422]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	15800.0	nM	PMID[34648295]
NPT81	Cell line	A549	Homo sapiens	IC50	=	2190.0	nM	PMID[34237623]
NPT784	Cell line	MDA-MB-468	Homo sapiens	Activity	=	-60.9	%	PMID[26994845]
NPT111	Cell line	K562	Homo sapiens	IC50	=	340.0	nM	PMID[35931243]
NPT81	Cell line	A549	Homo sapiens	IC50	=	1030.0	nM	PMID[35282680]
NPT83	Cell line	MCF7	Homo sapiens	IC50	<	10000.0	nM	PMID[35694689]
NPT306	Cell line	PC-3	Homo sapiens	IC50	=	380.0	nM	PMID[33774342]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	8216.0	nM	PMID[35084853]
NPT180	Cell line	HCT-8	Homo sapiens	IC50	=	21600.0	nM	PMID[35282680]
NPT180	Cell line	HCT-8	Homo sapiens	IC50	=	3980.0	nM	PMID[35282680]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	2990.0	nM	PMID[34678573]
NPT2410	Cell line	NCI-H1299	Homo sapiens	IC50	n.a.	n.a.	n.a.	PMID[34237623]
NPT405	Cell line	NCI-H226	Homo sapiens	GI50	<	100.0	nM	PMID[26994845]
NPT1317	Cell line	CCRF S-180	Mus musculus	TGI	=	61.1	%	PMID[33684825]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	6.85	10^-5 uM	PMID[33940466]
NPT1357	Cell line	H22	Mus musculus	Activity	=	51.9	%	PMID[34128674]
NPT181	Cell line	Bel-7402	Homo sapiens	IC50	=	1732.0	nM	PMID[33676300]
NPT400	Cell line	MDA-MB-435	Homo sapiens	GI50	<	100.0	nM	PMID[35694689]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	18140.0	nM	PMID[37856840]
NPT400	Cell line	MDA-MB-435	Homo sapiens	Activity	=	-30.9	%	PMID[26994845]
NPT111	Cell line	K562	Homo sapiens	IC50	=	460.0	nM	PMID[36780419]
NPT83	Cell line	MCF7	Homo sapiens	TGI	=	46.0	%	PMID[33160760]
NPT400	Cell line	MDA-MB-435	Homo sapiens	Activity	=	50.8	%	PMID[26994845]
NPT400	Cell line	MDA-MB-435	Homo sapiens	GI50	<	100.0	nM	PMID[26994845]
NPT181	Cell line	Bel-7402	Homo sapiens	IC50	=	128000.0	nM	PMID[34237623]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	670.0	nM	PMID[35339100]
NPT83	Cell line	MCF7	Homo sapiens	GI50	<	100.0	nM	PMID[26994845]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	17.2	%	PMID[26994845]
NPT83	Cell line	MCF7	Homo sapiens	GI50	<	10.0	ug.mL-1	PMID[36481599]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	1010.0	nM	PMID[36764122]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	112800.0	nM	PMID[37856840]
NPT81	Cell line	A549	Homo sapiens	IC50	=	780.0	nM	PMID[33689875]
NPT515	Cell line	SGC-7901	Homo sapiens	IC50	=	720.0	nM	PMID[35367708]
NPT3140	Cell line	MGC-803	Homo sapiens	IC50	=	480.0	nM	PMID[35367708]
NPT550	Cell line	T-24	Homo sapiens	IC50	=	1760.0	nM	PMID[38389893]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	820.0	nM	PMID[34992039]
NPT90	Cell line	DU-145	Homo sapiens	IC50	=	3480.0	nM	PMID[36493620]
NPT405	Cell line	NCI-H226	Homo sapiens	Activity	=	-38.3	%	PMID[26994845]
NPT2257	Cell line	MCF-10A	Homo sapiens	IC50	n.a.	n.a.	n.a.	PMID[33689875]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	27920.0	nM	PMID[34992039]
NPT81	Cell line	A549	Homo sapiens	IC50	=	255.0	nM	PMID[31865013]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	1280.0	nM	PMID[35123005]
NPT111	Cell line	K562	Homo sapiens	IC50	=	108.4	nM	PMID[34794817]
NPT148	Cell line	HCT-15	Homo sapiens	IC50	=	136000.0	nM	PMID[34678573]
NPT378	Cell line	NCI/ADR-RES	Homo sapiens	IC50	=	24920.0	nM	PMID[35390712]
NPT65	Cell line	HepG2	Homo sapiens	IC50	=	660.0	nM	PMID[33689875]
NPT116	Cell line	HL-60	Homo sapiens	IC50	=	60.0	nM	PMID[33333398]
NPT111	Cell line	K562	Homo sapiens	IC50	=	920.0	nM	PMID[35247755]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	860.0	nM	PMID[35390712]
NPT82	Cell line	MDA-MB-231	Homo sapiens	Inhibition	=	70.0	%	PMID[35121401]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1360.0	nM	PMID[34678573]
NPT181	Cell line	Bel-7402	Homo sapiens	Activity	=	73.5	%	PMID[34128674]
NPT3140	Cell line	MGC-803	Homo sapiens	IC50	=	2400.0	nM	PMID[38389893]
NPT659	Cell line	SMMC-7721	Homo sapiens	IC50	=	460.0	nM	PMID[35367708]
NPT380	Cell line	U-251	Homo sapiens	IC50	=	157.0	nM	PMID[34237623]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	720.0	nM	PMID[33689875]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	780.0	nM	PMID[38389893]
NPT81	Cell line	A549	Homo sapiens	IC50	=	12500.0	nM	PMID[35282680]
NPT81	Cell line	A549	Homo sapiens	IC50	=	152.0	nM	PMID[31865013]
NPT165	Cell line	HeLa	Homo sapiens	IC50	=	1030.0	nM	PMID[34597897]
NPT165	Cell line	HeLa	Homo sapiens	IC50	<	10000.0	nM	PMID[35694689]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	28.5	%	PMID[26994845]
NPT306	Cell line	PC-3	Homo sapiens	GI50	<	100.0	nM	PMID[35694689]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1.2	nM	PMID[33940466]
NPT2870	Cell line	Sarcoma-180	Mus musculus	TGI	=	234.0	%	PMID[35367708]
NPT744	Cell line	IMR-32	Homo sapiens	IC50	=	1700.0	nM	PMID[30114660]
NPT83	Cell line	MCF7	Homo sapiens	IC50	=	1310.0	nM	PMID[34992039]
NPT2466	Cell line	NCI-H358	Homo sapiens	IC50	<	5000.0	nM	PMID[35586422]
NPT165	Cell line	HeLa	Homo sapiens	GI50	<	80.0	ug.mL-1	PMID[31926469]
NPT146	Cell line	SK-OV-3	Homo sapiens	IC50	=	480.0	nM	PMID[36764122]
NPT83	Cell line	MCF7	Homo sapiens	Activity	=	-1.6	%	PMID[26994845]
NPT2257	Cell line	MCF-10A	Homo sapiens	IC50	=	890.0	nM	PMID[35390712]
NPT82	Cell line	MDA-MB-231	Homo sapiens	IC50	=	370.0	nM	PMID[35121401]
NPT784	Cell line	MDA-MB-468	Homo sapiens	GI50	=	10500.0	nM	PMID[26994845]
NPT405	Cell line	NCI-H226	Homo sapiens	Activity	=	57.4	%	PMID[26994845]
NPT181	Cell line	Bel-7402	Homo sapiens	IC50	=	0.369	nM	PMID[35152092]
NPT400	Cell line	MDA-MB-435	Homo sapiens	Activity	=	42.8	%	PMID[26994845]
NPT400	Cell line	MDA-MB-435	Homo sapiens	Activity	=	-26.6	%	PMID[26994845]
NPT788	Cell line	SNU1	Homo sapiens	IC50	=	2010.0	nM	PMID[35367708]
NPT4471	Cell line	Panel (12 tumour cell lines)	Homo sapiens	IC50	=	0.007	ug.mL-1	PMID[33831559]
NPT1460	Cell line	L929	Mus musculus	IC50	=	2040.0	nM	PMID[37593579]
NPT165	Cell line	HeLa	Homo sapiens	ID50	=	110.0	ng/ml	PMID[1271420]
NPT1893	Cell line	MEF	Mus musculus	ID50	=	7.0	ng/ml	PMID[1271420]
NPT1893	Cell line	MEF	Mus musculus	ID50	=	2.5	ng/ml	PMID[1271420]
NPT65	Cell line	HepG2	Homo sapiens	CC50	=	127000.0	nM	PMID[26675440]
NPT71	Cell line	HEK293	Homo sapiens	CC50	>	10000.0	nM	DOI[10.6019/CHEMBL4296181]
NPT24664	Cell line	518A2	Homo sapiens	Activity	=	98.0	%	PMID[20133021]
NPT24664	Cell line	518A2	Homo sapiens	Activity	=	74.0	%	PMID[20133021]
NPT20985	Cell line	MCF7-ADR	Homo sapiens	IC50	>	50000.0	nM	PMID[28720329]
NPT20985	Cell line	MCF7-ADR	Homo sapiens	Activity	=	0.44	%	PMID[28720329]
NPT20555	Organism	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	-0.77	%	DOI[10.21203/rs.3.rs-23951/v1]
NPT20555	Organism	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	7.1	%	DOI[10.6019/CHEMBL4495565]
NPT29101	Cell line	H69AR	Homo sapiens	IC50	=	15100.0	nM	PMID[35993848]
NPT28791	Cell line	NCI-H3255	Homo sapiens	IC50	=	1500.0	nM	PMID[34797067]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	=	6.3	n.a.	PMID[33676300]
NPT28438	Unchecked	Unchecked	n.a.	GI50	=	20.0	nM	PMID[32795767]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	=	1.32	n.a.	PMID[35282680]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	=	127.0	n.a.	PMID[35339100]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	n.a.	n.a.	n.a.	PMID[34794817]
NPT28438	Unchecked	Unchecked	n.a.	IC50	=	1180.0	nM	PMID[32485531]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	=	21.31	n.a.	PMID[34992039]
NPT23408	Cell line	K562/VCR	Homo sapiens	IC50	n.a.	n.a.	n.a.	PMID[33676300]
NPT28438	Unchecked	Unchecked	n.a.	IC50	=	5562.0	nM	PMID[34648295]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	=	320.9	n.a.	PMID[35084853]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	=	352.0	n.a.	PMID[34648295]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	=	5.43	n.a.	PMID[35282680]
NPT28438	Unchecked	Unchecked	n.a.	IC50	n.a.	n.a.	n.a.	PMID[34794817]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	=	6.2	n.a.	PMID[37856840]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	=	287.7	n.a.	PMID[34794817]
NPT28438	Unchecked	Unchecked	n.a.	Ratio IC50	=	8.18	n.a.	PMID[34649064]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	200.0	nM	PMID[11575942]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	100.0	nM	PMID[11575942]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	ED50	=	0.015	ug ml-1	PMID[9677271]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	EC50	=	110.0	nM	PMID[12027739]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	EC50	=	20.0	nM	PMID[12027739]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1300.0	nM	PMID[17067155]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	0.5	ug.mL-1	PMID[10579858]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	0.596	ug.mL-1	PMID[20045644]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	0.615	ug.mL-1	PMID[20045644]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	230.0	nM	PMID[19618898]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	23810.0	nM	PMID[20353152]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1020.0	nM	PMID[20133021]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	340.0	nM	PMID[20133021]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	170.0	nM	PMID[20133021]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	120.0	nM	PMID[20133021]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	59900.0	nM	PMID[20133021]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	35600.0	nM	PMID[20133021]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	18300.0	nM	PMID[20133021]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Activity	=	2.5	%	PMID[20133021]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Activity	=	15.4	%	PMID[20133021]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	100.0	nM	PMID[20444601]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	170.0	nM	PMID[20444601]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	64000.0	nM	PMID[20398972]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	<	1000.0	nM	PMID[20627721]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	49.66	ug.mL-1	PMID[20724170]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	140.0	nM	PMID[20554354]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	120.0	nM	PMID[20554354]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	2800.0	nM	PMID[21144748]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Inhibition	=	28.52	%	PMID[21296573]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Activity	=	67.34	%	PMID[21247667]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	170.0	nM	PMID[21459581]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	100.0	nM	PMID[21459581]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	19210.0	nM	PMID[21821321]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	5730.0	nM	PMID[23131338]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	4300.0	nM	DOI[10.1007/s00044-011-9703-4]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	2210.0	nM	PMID[23353738]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	6170.0	nM	PMID[23353738]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	110.0	nM	PMID[23353738]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	430.0	nM	PMID[25442319]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	380.0	nM	PMID[25442319]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	500.0	nM	PMID[25442319]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	54220.0	nM	PMID[25464884]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	2590.0	nM	PMID[25062006]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI	=	93.5	%	PMID[25064351]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	800.0	nM	PMID[25064351]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI	=	66.0	%	PMID[25128667]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	20.0	nM	PMID[25259515]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	18500.0	nM	PMID[25304898]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	11700.0	nM	PMID[25304898]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	11740.0	nM	PMID[25226363]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	4220.0	nM	PMID[25226363]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	1100.0	nM	PMID[25736997]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	5200.0	nM	PMID[25611131]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	4200.0	nM	PMID[25611131]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	760.0	nM	PMID[25739048]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	240.0	nM	PMID[25739048]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	20.0	nM	PMID[26506221]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	200.0	nM	PMID[26506221]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	500.0	nM	PMID[26506221]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	5000.0	nM	PMID[26810315]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	2500.0	nM	PMID[26810315]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	20.0	nM	DOI[10.1039/C5MD00289C]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	10.0	nM	DOI[10.1039/C5MD00289C]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	10550.0	nM	PMID[26832219]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	16.0	nM	PMID[26832219]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	4890.0	nM	PMID[26832219]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	820.0	nM	PMID[26832219]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	90.0	nM	PMID[26927425]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	520.0	nM	PMID[26945111]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1230.0	nM	PMID[26945111]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	23000.0	nM	PMID[26988802]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	3200.0	nM	PMID[26988802]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1000.0	nM	PMID[27240278]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	2500.0	nM	PMID[27318975]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	5000.0	nM	PMID[27318975]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	470.0	nM	PMID[27318123]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1060.0	nM	PMID[27318123]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1560.0	nM	PMID[27318123]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1460.0	nM	PMID[27318123]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	15170.0	nM	PMID[27318123]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	380.0	nM	PMID[27332142]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	EC50	=	700.0	nM	PMID[27344488]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	EC50	=	2300.0	nM	PMID[27344488]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	300.0	nM	PMID[27462726]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	67.0	nM	PMID[27462726]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1420.0	nM	PMID[27484510]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	470.0	nM	PMID[27484510]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1700.0	nM	PMID[27484510]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	710.0	nM	PMID[27484510]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	GI50	=	0.04	ug.mL-1	PMID[27598688]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1080.0	nM	PMID[27643560]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1340.0	nM	PMID[27643560]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	520.0	nM	PMID[27643560]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	880.0	nM	PMID[27643560]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	4960.0	nM	PMID[27643560]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	2310.0	nM	PMID[27643560]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1500.0	nM	PMID[27654394]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	1590.0	nM	PMID[27654394]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	740.0	nM	PMID[27654394]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	IC50	=	5310.0	nM	PMID[27654394]
NPT23712	Cell line	KG-1a	Homo sapiens	IC50	=	80.0	nM	PMID[28068601]
NPT23297	Cell line	LS180	Homo sapiens	Inhibition	=	70.0	%	PMID[30243156]
NPT23713	Cell line	FHC	Homo sapiens	IC50	=	57.0	nM	PMID[30006167]
NPT25041	Cell line	MDA-MB-436	Homo sapiens	IC50	=	2030.0	nM	PMID[31398033]
NPT20	Organism	Candida albicans	Candida albicans	MIC	>	10000.0	nM	DOI[10.6019/CHEMBL4296181]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	10000.0	nM	DOI[10.6019/CHEMBL4296181]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	CC50	=	4100.0	nM	PMID[10560735]
NPT22774	Cell line	JIMT-1	Homo sapiens	Activity	<	90.0	%	PMID[28177244]
NPT23193	Cell line	Bel7402/5-FU	Homo sapiens	IC50	=	8360.0	nM	PMID[31553932]
NPT21742	Cell line	L02	Homo sapiens	IC50	=	790.0	nM	PMID[30837097]
NPT21742	Cell line	L02	Homo sapiens	IC50	=	13500.0	nM	PMID[31013087]
NPT21742	Cell line	L02	Homo sapiens	IC50	=	500.0	nM	PMID[31904949]
NPT23193	Cell line	Bel7402/5-FU	Homo sapiens	IC50	=	10950.0	nM	PMID[30677614]
NPT85	Organism	Filobasidiella neoformans	Cryptococcus neoformans	MIC	>	10000.0	nM	DOI[10.6019/CHEMBL4296181]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	10000.0	nM	DOI[10.6019/CHEMBL4296181]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	10000.0	nM	DOI[10.6019/CHEMBL4296181]
NPT2922	Organism	Staphylococcus aureus subsp. aureus	Staphylococcus aureus subsp. aureus	MIC	=	10000.0	nM	DOI[10.6019/CHEMBL4296181]
NPT27801	Cell line	HeLa/Fucci2	Homo sapiens	IC50	=	2000.0	nM	PMID[31848114]
NPT21742	Cell line	L02	Homo sapiens	IC50	=	700.0	nM	PMID[34176266]
NPT21742	Cell line	L02	Homo sapiens	IC50	=	200.0	nM	PMID[35993848]
NPT20972	Cell line	SU.86.86	Homo sapiens	IC50	=	330.0	nM	PMID[36583957]
NPT28855	Cell line	ECa-109 cell line	Homo sapiens	IC50	=	0.201	nM	PMID[35152092]
NPT25039	Cell line	KB-V1	Homo sapiens	IC50	n.a.	n.a.	n.a.	PMID[34794817]
NPT21742	Cell line	L02	Homo sapiens	IC50	=	23540.0	nM	PMID[38389893]
NPT27	Others	Unspecified	n.a.	IC50	=	800.0	nM	PMID[20398972]
NPT2	Others	Unspecified	n.a.	FC	=	2.1	n.a.	PMID[20724170]
NPT2	Others	Unspecified	n.a.	FC	=	2.8	n.a.	PMID[20724170]
NPT2	Others	Unspecified	n.a.	FC	=	5.7	n.a.	PMID[20724170]
NPT24749	Organism	Ebolavirus	Ebolavirus	Inhibition	=	97.0	%	PMID[20421407]
NPT27	Others	Unspecified	n.a.	Inhibition	=	25.0	%	PMID[20421407]
NPT27	Others	Unspecified	n.a.	IC50	=	1110.0	nM	PMID[24153206]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	50.0	n.a.	PMID[26832219]
NPT27	Others	Unspecified	n.a.	IC50	=	68.0	nM	PMID[26866967]
NPT27	Others	Unspecified	n.a.	IC50	=	38020.0	nM	PMID[27073052]
NPT22128	Cell line	K562/A02	Homo sapiens	IC50	=	24460.0	nM	PMID[28068095]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	41.5	n.a.	PMID[28068095]
NPT22128	Cell line	K562/A02	Homo sapiens	TGI	=	18.6	%	PMID[28068095]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	4.0	n.a.	PMID[28068601]
NPT2	Others	Unspecified	n.a.	IC50	=	1770.0	nM	PMID[28222318]
NPT22128	Cell line	K562/A02	Homo sapiens	IC50	=	53950.0	nM	PMID[28301155]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	42.6	n.a.	PMID[28333459]
NPT23299	Cell line	K562/Adr	Homo sapiens	IC50	=	3310.2	nM	PMID[28333459]
NPT22128	Cell line	K562/A02	Homo sapiens	IC50	=	96910.0	nM	PMID[28645831]
NPT2	Others	Unspecified	n.a.	IC50	=	25200.0	nM	PMID[28418245]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	29.5	n.a.	PMID[29903663]
NPT2	Others	Unspecified	n.a.	IC50	=	49750.0	nM	PMID[29903663]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	22.72	n.a.	PMID[29903663]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	1222.1	n.a.	PMID[28763646]
NPT2	Others	Unspecified	n.a.	IC50	=	45000.0	nM	PMID[29286660]
NPT22128	Cell line	K562/A02	Homo sapiens	IC50	=	25040.0	nM	PMID[29335204]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	64.0	n.a.	PMID[29335204]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	1221.53	n.a.	PMID[29754076]
NPT22128	Cell line	K562/A02	Homo sapiens	IC50	=	65570.0	nM	PMID[29631786]
NPT2	Others	Unspecified	n.a.	IC50	=	340.0	nM	PMID[30006167]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	0.14	n.a.	PMID[30006167]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	0.16	n.a.	PMID[30006167]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	0.45	n.a.	PMID[30739826]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	133.0	n.a.	PMID[30837097]
NPT2	Others	Unspecified	n.a.	IC50	=	1840.0	nM	PMID[31977207]
NPT2	Others	Unspecified	n.a.	IC50	=	1732.0	nM	PMID[30530194]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	6.3	n.a.	PMID[30530194]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	367.3	n.a.	PMID[27213819]
NPT2	Others	Unspecified	n.a.	IC50	=	144350.0	nM	PMID[28818459]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	215.4	n.a.	PMID[28818459]
NPT23299	Cell line	K562/Adr	Homo sapiens	IC50	=	18779.0	nM	PMID[27503681]
NPT2	Others	Unspecified	n.a.	IC50	=	1320.0	nM	PMID[30677614]
NPT23298	Cell line	A549/TR	Homo sapiens	IC50	=	42570.0	nM	PMID[30677614]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	0.12	n.a.	PMID[30677614]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	0.01	n.a.	PMID[30677614]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	0.04	n.a.	PMID[30677614]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	10000.0	nM	DOI[10.6019/CHEMBL4296181]
NPT23299	Cell line	K562/Adr	Homo sapiens	IC50	=	3310.2	nM	PMID[31171403]
NPT22128	Cell line	K562/A02	Homo sapiens	IC50	=	23420.0	nM	PMID[33132117]
NPT2	Others	Unspecified	n.a.	Ratio IC50	=	28.21	n.a.	PMID[33132117]
NPT2	Others	Unspecified	n.a.	IC50	=	1100.0	nM	PMID[33097300]
NPT22128	Cell line	K562/A02	Homo sapiens	IC50	=	58600.0	nM	PMID[36780419]
NPT22128	Cell line	K562/A02	Homo sapiens	IC50	=	2400.0	nM	PMID[36708676]
NPT28722	Cell line	AG1523	Homo sapiens	IC50	=	400.0	nM	PMID[33774342]
NPT22128	Cell line	K562/A02	Homo sapiens	Activity	n.a.	n.a.	n.a.	PMID[36780419]
NPT22128	Cell line	K562/A02	Homo sapiens	Activity	=	526.45	mm3	PMID[36708676]
NPT23299	Cell line	K562/Adr	Homo sapiens	IC50	=	31191.0	nM	PMID[34794817]
NPT22128	Cell line	K562/A02	Homo sapiens	IC50	=	78340.0	nM	PMID[35247755]

In vivo activity

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	0.5	%	PMID[25208345]
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	0.29	g	PMID[25304898]
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	0.11	g	PMID[25304898]
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	1.6	g	PMID[25304898]
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	0.16	g	PMID[25304898]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Ratio	=	1.0	n.a.	PMID[690999]

Experimental ADME

Experiment Model	Experiment Tissue	ADME Type	ADME Relation	ADME Value	ADME Unit	Reference
Mus musculus	n.a.	T1/2	=	23.0	hr	PMID[34128674]

Experimental Toxicity

Quantitative toxicity

Experiment Model	Experiment Organism	Toxicity Type	Toxicity Relation	Toxicity Value	Toxicity Unit	Reference

Common Abbreviations:
LC: Lethal Concentration; LD: Lethal Dose; LT:Lethal Time; NOAEL: No-observed-adverse-effect Level; BMDL: Benchmark Dose Lower Confidence Limit; BMD: Benchmark Dose; BMC:Benchmark Concentration; LOAEL: Lowest Observed Adverse Effect Level; RfD:Reference Dose; RfC:Reference Concentration; MRL: Minimal Risk Level; MEG: Maximum Exposure Guideline; PAC: Protective Action Criteria

Categorical toxicity labels

Hepatotoxicity	Carcinogenicity	Mutagenicity	Cardiotoxicity	Respiratory Toxicity	Eye Irritation	Endocrine Disruption

Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP toxicity records from domain-specific databases. These databases include:
☉ ToxValDB: a curated database that compiles quantitative toxicity values for chemicals from diverse public sources to support toxicological research and risk assessment.
☉ TOXRIC: a comprehensive, free-to-access, online database providing toxicological/feature data. The toxicity labels are retrieved from this database. [PMID: 36400569]

Chemically structural similarity

Similar Active Natural Products in NPASS

Top-200 similar NPs were calculated against the active-NP-set (includes approximately 50,000 NPs with experimentally-derived bioactivity available in NPASS)

Similarity is measured using the Tanimoto coefficient (Tc) , which compares the binary fingerprints of two molecules. Tc is calculated as the intersection divided by the union of '1' bits in the fingerprints, ranging from 0 to 1, with 1 indicating highest similarity.

● The left chart: Distribution of similarity level between NPC468994 and all remaining natural products in the NPASS database.
● The right table: Most similar natural products (Tc>=0.5 or Top200).

range	Tanimoto Coefficient
0-0.1	10320
0.1-0.2	37799
0.2-0.3	1697
0.3-0.4	28
0.4-0.5	4
0.5-0.6	0
0.6-0.7	2
0.7-0.8	13
0.8-0.85	2
0.85-0.9	1
0.9-0.95	1
0.95-1	2

Similarity Score	Similarity Level	Natural Product ID
0.9865	High Similarity	NPC261012
0.9865	High Similarity	NPC314738
0.9079	High Similarity	NPC487573
0.8947	High Similarity	NPC109403
0.8101	Intermediate Similarity	NPC603200
0.8025	Intermediate Similarity	NPC601855
0.7308	Intermediate Similarity	NPC611971
0.6854	Remote Similarity	NPC600087
0.6163	Remote Similarity	NPC602774

Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

● The left chart: Distribution of similarity level between NPC468994 and all drugs/candidates.
● The right table: Most similar clinical/approved drugs (Tc>=0.5 or Top200).

range	Tanimoto Coefficient
0-0.1	2508
0.1-0.2	6526
0.2-0.3	86
0.3-0.4	0
0.4-0.5	4
0.5-0.6	4
0.6-0.7	3
0.7-0.8	13
0.8-0.85	0
0.85-0.9	1
0.9-0.95	1
0.95-1	4

Similarity Score	Similarity Level	Drug ID	Developmental Stage
1.0	High Similarity	NPD6779	Approved
1.0	High Similarity	NPD6780	Approved
0.9865	High Similarity	NPD6781	Phase 4
0.9865	High Similarity	NPD6782	Phase 4
0.9079	High Similarity	NPD6777	Approved
0.8947	High Similarity	NPD6778	Phase 4
0.7727	Intermediate Similarity	NPD6776	Approved
0.7436	Intermediate Similarity	NPD6534	Approved
0.7363	Intermediate Similarity	NPD7870	Phase 2
0.7308	Intermediate Similarity	NPD6535	Phase 4
0.7253	Intermediate Similarity	NPD7871	Phase 2
0.7174	Intermediate Similarity	NPD7696	Phase 3
0.7174	Intermediate Similarity	NPD7697	Phase 3
0.7174	Intermediate Similarity	NPD7698	Approved
0.7158	Intermediate Similarity	NPD7801	Approved
0.7011	Intermediate Similarity	NPD7699	Phase 2
0.7011	Intermediate Similarity	NPD7700	Phase 2
0.7	Intermediate Similarity	NPD8058	Clinical (unspecified phase)
0.7	Intermediate Similarity	NPD8059	Phase 3
0.6566	Remote Similarity	NPD7701	Phase 2
0.6413	Remote Similarity	NPD6823	Phase 2
0.625	Remote Similarity	NPD8155	Clinical (unspecified phase)
0.59	Remote Similarity	NPD7435	Phase 2
0.5755	Remote Similarity	NPD7874	Phase 4
0.5755	Remote Similarity	NPD7875	Clinical (unspecified phase)
0.5225	Remote Similarity	NPD7879	Clinical (unspecified phase)

Bioactivity similarity

Similar Natural Products in NPASS

Similarity level is defined by Bioactivity similarity was calculated based on bioactivity descriptors of compounds. The bioactivity descriptors were calculated by a recently developed AI algorithm Chemical Checker (CC) [Nature Biotechnology, 38:1087–1096, 2020; Nature Communications, 12:3932, 2021], which evaluated bioactivity similarities at five levels:
☉ A: chemistry similarity;
☉ B: biological targets similarity;
☉ C: networks similarity;
☉ D: cell-based bioactivity similarity;
☉ E: similarity based on clinical data.
Those 5 categories of CC bioactivity descriptors were calculated and then subjected to manifold projection using UMAP algorithm, to project all NPs on a 2-Dimensional space. The current NP was highlighted with a small circle in the 2-D map. Below figures: left-to-right, A-to-E.

A: chemistry similarity

B: biological targets similarity

C: networks similarity

D: cell-based bioactivity similarity

E: similarity based on clinical data