Natural Product: NPC43850

Natural Product ID:  NPC43850
Common Name:   Kanamycin
IUPAC Name:   (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol
Synonyms:   Kanamycin
Molecular Formula:   C18H36N4O11
Standard InCHIKey:  SBUJHOSQTJFQJX-NOAMYHISSA-N
Standard InCHI:  InChI=1S/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1
Canonical SMILES:  OC[C@H]1O[C@H](O[C@H]2[C@H](N)C[C@@H]([C@H]([C@@H]2O)O[C@H]2O[C@H](CN)[C@H]([C@@H]([C@H]2O)O)O)N)[C@@H]([C@H]([C@@H]1O)N)O
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   BGC0000702;BGC0000703;BGC0000704;BGC0000705;BGC0000706 ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO13391 Streptomyces hygroscopicus Species Streptomycetaceae Bacteria PMID[24224794]
NPO22810 Streptomyces Species Streptomycetaceae Bacteria StreptomeDB*
NPO28993.22 Streptomyces venezuelae yj003 Subspecies Streptomycetaceae Bacteria StreptomeDB*
NPO896.1 Streptomyces kanamyceticus 12-6 Subspecies Streptomycetaceae Bacteria StreptomeDB*
NPO13439 Streptomyces canus Species Streptomycetaceae Bacteria StreptomeDB*
NPO896 Streptomyces kanamyceticus Species Streptomycetaceae Bacteria StreptomeDB*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.05 ug/ml 3701779
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 125 ug/ml 3701779
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 125 ug/ml 3701779
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC > 125 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 63 ug/ml 3701779
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1 ug/ml 3701779
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 125 ug/ml 3701779
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 32 ug/ml 3701779
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml 3701779
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC = 2 ug/ml 3701779
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC = 0.5 ug/ml 3701779
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC = 2 ug/ml 3701779
NPT2895 Organism Providencia stuartii Providencia stuartii MIC = 0.5 ug/ml 3701779
NPT2895 Organism Providencia stuartii Providencia stuartii MIC = 4 ug/ml 3701779
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 1 ug/ml 3701779
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 125 ug/ml 3701779
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 63 ug/ml 3701779
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 3701779
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 3.13 ug/ml 3934384
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 6.25 ug/ml 3934384
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 100 ug/ml 3934384
NPT1828 Organism Mycobacterium kansasii Mycobacterium kansasii MIC = 25 ug/ml 3934384
NPT86 Organism Mycobacterium intracellulare Mycobacterium intracellulare MIC = 6.25 ug/ml 3934384
NPT2 Others Unspecified Kd = 3460 nM 12127547
NPT2 Others Unspecified Kd = 2080 nM 12127547
NPT2 Others Unspecified Kd = 13600 nM 12127547
NPT2 Others Unspecified Kd = 2640 nM 12127547
NPT19 Organism Escherichia coli Escherichia coli MIC > 125 ug/ml 6244410
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 6244410
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC = 125 ug/ml 6244410
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC <= 0.25 ug/ml 6244410
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 125 ug/ml 6244410
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 6244410
NPT19 Organism Escherichia coli Escherichia coli IC50 = 40 nM 12139453
NPT2 Others Unspecified IC50 = 80 nM 12139453
NPT2896 Individual Protein Lysosomal phospholipase A1 Rattus norvegicus IC50 = 110000 nM 2016725
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 7473599
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 7473599
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 7473599
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 7473599
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 4 ug/ml 7473599
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 8 ug/ml 7473599
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 7473599
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 4 ug/ml 7473599
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 16 ug/ml 7473599
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 32 ug/ml 7473599
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 7473599
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 128 ug/ml 7473599
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 128 ug/ml 7473599
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 7473599
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 128 ug/ml 7473599
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 64 ug/ml 7473599
NPT1248 Organism Serratia marcescens Serratia marcescens MIC > 128 ug/ml 7473599
NPT2899 Individual Protein Phosphatidylserine-specific phospholipase A1 Rattus norvegicus IC50 = 39 ug/ml 7473599
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis Inhibition = 90 % 15225698
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC < 0.2 ug/ml 16005211
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 15913995
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 15913995
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 15913995
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 15913995
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 32 ug/ml 16202590
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 16 ug/ml 16202590
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 > 128 ug/ml 16202590
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 = 2 ug/ml 16202590
NPT19 Organism Escherichia coli Escherichia coli IC50 = 400 nM 16890435
NPT19 Organism Escherichia coli Escherichia coli IZ = 21 mm 17149863
NPT19 Organism Escherichia coli Escherichia coli IZ = 22 mm 17149863
NPT19 Organism Escherichia coli Escherichia coli IZ = 17 mm 17149863
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 17088477
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 17088477
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC = 256 ug/ml 17088477
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC = 8 ug/ml 17088477
NPT2 Others Unspecified MIC = 500 ug/ml 17060530
NPT2 Others Unspecified MIC > 500 ug/ml 17060530
NPT2900 Organism Bifidobacterium longum Bifidobacterium longum MIC = 500 ug/ml 17060530
NPT2900 Organism Bifidobacterium longum Bifidobacterium longum MIC = 250 ug/ml 17060530
NPT2901 Organism Bifidobacterium thermophilum Bifidobacterium thermophilum MIC > 500 ug/ml 17060530
NPT2 Others Unspecified MIC = 0.98 ug/ml 17060530
NPT2 Others Unspecified MIC = 250 ug/ml 17060530
NPT2901 Organism Bifidobacterium thermophilum Bifidobacterium thermophilum MIC = 500 ug/ml 17060530
NPT2 Others Unspecified MIC = 125 ug/ml 17060530
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC < 8 ug/ml 17043131
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC > 64 ug/ml 17043131
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC < 64 ug/ml 17043131
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC = 8 ug/ml 17043131
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 17194835
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 256 ug/ml 17194835
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 17194835
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 512 ug/ml 17194835
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1024 ug/ml 17194835
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 17210767
NPT19 Organism Escherichia coli Escherichia coli MIC > 512 ug/ml 17210767
NPT19 Organism Escherichia coli Escherichia coli MIC = 6 ug/ml 17210778
NPT19 Organism Escherichia coli Escherichia coli MIC > 250 ug/ml 17210778
NPT19 Organism Escherichia coli Escherichia coli Ratio = 0.87 17210778
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 17220425
NPT19 Organism Escherichia coli Escherichia coli MIC = 128 ug/ml 17220425
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 17220425
NPT19 Organism Escherichia coli Escherichia coli IC50 = 400 nM 17188860
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.39 ug/ml 17194508
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.9 ug/ml 17194508
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 3.9 ug/ml 17194508
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 17194508
NPT21 Organism Aspergillus niger Aspergillus niger MIC > 50 ug/ml 17194508
NPT20 Organism Candida albicans Candida albicans MIC > 50 ug/ml 17194508
NPT329 Organism Trichophyton rubrum Trichophyton rubrum MIC > 50 ug/ml 17194508
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.39 ug/ml 17418583
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 17418583
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.9 ug/ml 17418583
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 3.9 ug/ml 17418583
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC < 3 ug/ml 17150357
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 64 ug/ml 17257839
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC = 0.5 ug/ml 17257839
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.25 ug/ml 17257839
NPT79 Organism Bacillus subtilis Bacillus subtilis MBC = 4 ug/ml 17257839
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 17257839
NPT19 Organism Escherichia coli Escherichia coli MBC = 0.25 ug/ml 17257839
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 17257839
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC > 128 ug/ml 17257839
NPT766 Organism Proteus vulgaris Proteus vulgaris MIC = 0.25 ug/ml 17257839
NPT766 Organism Proteus vulgaris Proteus vulgaris MBC = 0.5 ug/ml 17257839
NPT729 Organism Micrococcus luteus Micrococcus luteus MIC = 0.25 ug/ml 17257839
NPT729 Organism Micrococcus luteus Micrococcus luteus MBC = 0.25 ug/ml 17257839
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 4 ug/ml 17257839
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC = 0.25 ug/ml 17257839
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MBC = 0.25 ug/ml 17257839
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.39 ug/ml 17570664
NPT19 Organism Escherichia coli Escherichia coli MBC = 0.39 ug/ml 17570664
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.39 ug/ml 17570664
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC = 0.78 ug/ml 17570664
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 6.25 ug/ml 17570664
NPT79 Organism Bacillus subtilis Bacillus subtilis MBC = 6.25 ug/ml 17570664
NPT729 Organism Micrococcus luteus Micrococcus luteus MIC = 0.39 ug/ml 17570664
NPT729 Organism Micrococcus luteus Micrococcus luteus MBC = 0.39 ug/ml 17570664
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 28 mm 17570664
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 2.5 ug/ml 17844996
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC50 = 8 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC90 = 8 ug/ml 17353252
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC50 = 4 ug/ml 17353252
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC90 = 8 ug/ml 17353252
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC50 = 8 ug/ml 17353252
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC90 = 32 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC > 128 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 16 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 8 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 4 ug/ml 17353252
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC > 128 ug/ml 17353252
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC = 32 ug/ml 17353252
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 17438056
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 17438056
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC = 4 ug/ml 17438056
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.12 ug/ml 17450125
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 25 ug/ml 17450125
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 3.12 ug/ml 17450125
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 62.5 ug/ml 17450125
NPT1531 Organism Enterococcus faecium Enterococcus faecium MIC = 0.39 ug/ml 17450125
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 1.56 ug/ml 17450125
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.39 ug/ml 18262793
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.562 ug/ml 18262793
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 3.125 ug/ml 18262793
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 3.125 ug/ml 18262793
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.39 ug/ml 18192085
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.9 ug/ml 18192085
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 3.9 ug/ml 18192085
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 18192085
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 1 ug/ml 17977623
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 17977623
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 3.9 ug/ml 17977623
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.9 ug/ml 17977623
NPT19 Organism Escherichia coli Escherichia coli MIC < 7.8 ug/ml 15104491
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC < 7.8 ug/ml 15104491
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC > 128 ug/ml 17438050
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 17438050
NPT19 Organism Escherichia coli Escherichia coli MIC <= 0.25 ug/ml 17438050
NPT19 Organism Escherichia coli Escherichia coli MIC > 512 ug/ml 17470656
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 17470660
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 17470660
NPT1245 Organism Streptococcus pasteurianus Streptococcus pasteurianus MIC > 4096 ug/ml 17371822
NPT1245 Organism Streptococcus pasteurianus Streptococcus pasteurianus MIC = 4096 ug/ml 17371822
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 16 ug/ml 17371822
NPT2904 Organism Streptococcus equinus Streptococcus equinus MIC = 128 ug/ml 17371822
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 3500 nM 15497961
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 5 ug/ml 9428161
NPT2 Others Unspecified Kd > 1000000 nM 18789700
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.39 ug/ml 19147367
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.562 ug/ml 19147367
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 3.125 ug/ml 19147367
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 3.125 ug/ml 19147367
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 17548499
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 17548499
NPT19 Organism Escherichia coli Escherichia coli MIC = 128 ug/ml 17548499
NPT19 Organism Escherichia coli Escherichia coli Ratio = 1 17548499
NPT485 Organism Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 MIC = 2.5 ug/ml 17067157
NPT19 Organism Escherichia coli Escherichia coli MIC = 28 ug/ml 10514301
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 140 ug/ml 10514301
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 14 ug/ml 10514301
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 140 ug/ml 10514301
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 560 ug/ml 10514301
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 17526756
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 17526756
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 17526756
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 17724159
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 17724159
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 17724159
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 17724159
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 20 mm 19027993
NPT19 Organism Escherichia coli Escherichia coli IZ = 15 mm 19027993
NPT1248 Organism Serratia marcescens Serratia marcescens IZ = 45 mm 19027993
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis IZ = 40 mm 19027993
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis IC50 = 2.5 ug/ml 19368377
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC >= 256 ug/ml 17938184
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC = 1 ug/ml 17938184
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.5 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 3 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 6 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 24 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 12 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 128 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 48 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 32 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 64 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 96 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 256 ug/ml 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 1000 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 200 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 30 17923494
NPT16 Organism Staphylococcus aureus Staphylococcus aureus FC = 3 17923494
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC >= 256 ug/ml 17938184
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 128 ug/ml 17938184
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 17938184
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 17938184
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 17875999
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 17875999
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 17875999
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 19349095
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 19349095
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 19349095
NPT19 Organism Escherichia coli Escherichia coli MIC = 10000 nM 19888756
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 200000 nM 19888756
NPT1550 Organism Bacillus anthracis Bacillus anthracis MIC = 5000 nM 19888756
NPT729 Organism Micrococcus luteus Micrococcus luteus MIC = 20000 nM 19888756
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 1.56 ug/ml 19828313
NPT2 Others Unspecified MIC = 0.3 ug/ml 19828313
NPT1513 Organism Mycobacterium avium Mycobacterium avium MIC > 100 ug/ml 19828313
NPT1513 Organism Mycobacterium avium Mycobacterium avium MIC = 1.56 ug/ml 19828313
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC = 3.13 ug/ml 19828313
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 12.5 ug/ml 19828313
NPT19 Organism Escherichia coli Escherichia coli MIC = 12.5 ug/ml 19828313
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 5 ug/ml 19679378
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 20133139
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 20133139
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 2.5 ug/ml 19943622
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC = 0.2 ug/ml 19874044
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.13 ug/ml 20304657
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 3.13 ug/ml 20304657
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 1.56 ug/ml 20304657
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.56 ug/ml 20304657
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 20188576
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 20188576
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 33.02 umol/ml 20207052
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 4.13 umol/ml 20207052
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 66.05 umol/ml 20207052
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.39 ug/ml 20181415
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 5.08 ug/ml 20181415
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.28 ug/ml 20181415
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.1 ug/ml 20381216
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 3.1 ug/ml 20381216
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.4 ug/ml 20381216
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 20381216
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 37 mm 20590100
NPT19 Organism Escherichia coli Escherichia coli IZ = 38 mm 20590100
NPT19 Organism Escherichia coli Escherichia coli IZ = 21 mm 19848433
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 15 mm 19848433
NPT1531 Organism Enterococcus faecium Enterococcus faecium IZ = 10 mm 19848433
NPT20 Organism Candida albicans Candida albicans IZ = 0 mm 19848433
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 0 mm 19848433
NPT19 Organism Escherichia coli Escherichia coli IZ = 37 mm 19848433
NPT19 Organism Escherichia coli Escherichia coli MIC > 1024 ug/ml 20038628
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens Activity = 3.13 ug/ml 20557983
NPT19 Organism Escherichia coli Escherichia coli Activity = 3.13 ug/ml 20557983
NPT79 Organism Bacillus subtilis Bacillus subtilis Activity = 1.56 ug/ml 20557983
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 1.56 ug/ml 20557983
NPT115 Organism Mycobacterium tuberculosis H37Ra Mycobacterium tuberculosis H37Ra MIC = 2.5 ug/ml 20691508
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium EC50 = 3.5 ug/ml 18172002
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium EC50 = 29 ug/ml 18172002
NPT2 Others Unspecified EC50 = 6.5 ug/ml 18172002
NPT2 Others Unspecified EC50 = 130 ug/ml 18172002
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC = 8 ug/ml 18172002
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC = 250 ug/ml 18172002
NPT2 Others Unspecified MIC = 16 ug/ml 18172002
NPT2 Others Unspecified MIC = 250 ug/ml 18172002
NPT1863 Organism Staphylococcus saprophyticus Staphylococcus saprophyticus MIC50 = 0.25 ug/ml 18362191
NPT1863 Organism Staphylococcus saprophyticus Staphylococcus saprophyticus MIC90 = 0.5 ug/ml 18362191
NPT1863 Organism Staphylococcus saprophyticus Staphylococcus saprophyticus MIC = 0.25 ug/ml 18362191
NPT1863 Organism Staphylococcus saprophyticus Staphylococcus saprophyticus MIC = 0.5 ug/ml 18362191
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC > 1024 ug/ml 20308368
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC = 256 ug/ml 20308368
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 20211889
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 20211889
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 20211889
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 20211889
NPT312 Organism Saccharomyces cerevisiae Saccharomyces cerevisiae IZ = 1 mm 20739103
NPT312 Organism Saccharomyces cerevisiae Saccharomyces cerevisiae IZ = 3 mm 20739103
NPT2906 Organism Mycobacterium ulcerans Mycobacterium ulcerans MIC <= 5 ug/ml 20421401
NPT2 Others Unspecified MIC = 16 ug/ml 20421403
NPT19 Organism Escherichia coli Escherichia coli MIC = 256 ug/ml 20421403
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 20421403
NPT1827 Organism Mycobacterium bovis Mycobacterium bovis MIC = 1 ug/ml 18955515
NPT2907 Organism Burkholderia pseudomallei Burkholderia pseudomallei MIC = 4 ug/ml 20498323
NPT2907 Organism Burkholderia pseudomallei Burkholderia pseudomallei MIC = 64 ug/ml 20498323
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 20547812
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 20547812
NPT2 Others Unspecified MIC = 1 ug/ml 20547812
NPT2 Others Unspecified MIC = 16 ug/ml 20547812
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 20547812
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 20547812
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 256 ug/ml 20547812
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC = 1 ug/ml 20547812
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC = 16 ug/ml 20547812
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 18519712
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 128 ug/ml 18519712
NPT1101 Organism Staphylococcus aureus subsp. aureus RN4220 Staphylococcus aureus subsp. aureus RN4220 MIC = 2 ug/ml 18519725
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4 ug/ml 18519725
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 18519725
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC = 1.5 ug/ml 18519732
NPT2908 Organism Streptomyces coelicolor Streptomyces coelicolor MIC = 0.8 ug/ml 19104019
NPT2908 Organism Streptomyces coelicolor Streptomyces coelicolor MIC = 0.5 ug/ml 19104019
NPT2908 Organism Streptomyces coelicolor Streptomyces coelicolor MIC = 1 ug/ml 19104019
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC > 1024 ug/ml 19029325
NPT2909 Organism Shigella flexneri Shigella flexneri Activity = 16 ug/ml 19064898
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii Activity = 16 ug/ml 19064898
NPT2 Others Unspecified Activity = 16 ug/ml 19064898
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC = 1 ug/ml 21111625
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 125 ug/ml 21111625
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 125 ug/ml 21111625
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml 21111625
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 21111625
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 21111625
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 19349516
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 19349516
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 19349516
NPT19 Organism Escherichia coli Escherichia coli MIC = 128 ug/ml 19349516
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC = 0.6 ug/ml 19223646
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC = 2.4 ug/ml 19223646
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC = 1.2 ug/ml 19223646
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MBC = 20 ug/ml 19223646
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MBC = 10 ug/ml 19223646
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 1.56 ug/ml 19752278
NPT1248 Organism Serratia marcescens Serratia marcescens MIC > 400 ug/ml 19752278
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC = 50 ug/ml 19581465
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC = 10 ug/ml 19581465
NPT2 Others Unspecified MIC > 64 ug/ml 19596870
NPT1101 Organism Staphylococcus aureus subsp. aureus RN4220 Staphylococcus aureus subsp. aureus RN4220 MIC = 4 ug/ml 19470508
NPT1101 Organism Staphylococcus aureus subsp. aureus RN4220 Staphylococcus aureus subsp. aureus RN4220 MIC = 32 ug/ml 19470508
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 1.56 ug/ml 21232949
NPT2 Others Unspecified MIC = 0.3 ug/ml 21232949
NPT2 Others Unspecified MIC = 3.13 ug/ml 21232949
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 12.5 ug/ml 21232949
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 100 ug/ml 21232949
NPT19 Organism Escherichia coli Escherichia coli MIC = 12.5 ug/ml 21232949
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 2 ug/ml 20713679
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 16 ug/ml 20713679
NPT2 Others Unspecified MIC = 0.5 ug/ml 19721076
NPT2910 Organism Campylobacter jejuni Campylobacter jejuni MIC > 256 ug/ml 18505858
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC50 = 0.43 ug/ml 21330140
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 1 ug/ml 21330140
NPT1522 Organism Neisseria gonorrhoeae Neisseria gonorrhoeae MIC = 2 ug/ml 19822705
NPT19 Organism Escherichia coli Escherichia coli MIC = 125 ug/ml 20855745
NPT19 Organism Escherichia coli Escherichia coli MIC = 15.63 ug/ml 20855745
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 20855745
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC >= 128 ug/ml 20876371
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4 ug/ml 20876371
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 64 ug/ml 20876371
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.78 ug/ml 20876376
NPT19 Organism Escherichia coli Escherichia coli MIC = 12.5 ug/ml 20876376
NPT19 Organism Escherichia coli Escherichia coli MIC = 6.25 ug/ml 20876376
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.56 ug/ml 20876376
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.125 ug/ml 20876376
NPT19 Organism Escherichia coli Escherichia coli MIC = 25 ug/ml 20876376
NPT19 Organism Escherichia coli Escherichia coli MIC = 50 ug/ml 20876376
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 10 ug/ml 20937780
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 100 ug/ml 20937780
NPT1107 Organism Mycobacterium smegmatis str. MC2 155 Mycobacterium smegmatis str. MC2 155 MIC = 0.5 ug/ml 20937780
NPT1228 Organism Streptococcus pyogenes Streptococcus pyogenes Ratio = 16 21115784
NPT19 Organism Escherichia coli Escherichia coli Activity = 3.3 % 20733038
NPT19 Organism Escherichia coli Escherichia coli Activity = 2.9 % 20733038
NPT19 Organism Escherichia coli Escherichia coli Activity = 19.3 % 20733038
NPT19 Organism Escherichia coli Escherichia coli Activity = 4.9 % 20733038
NPT1465 Organism Legionella pneumophila Legionella pneumophila MIC = 12.5 ug/ml 21244021
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 1 ug/ml 17624635
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.45 ug/ml 17624635
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 3.9 ug/ml 17624635
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 17624635
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 25.1 mm 21474216
NPT79 Organism Bacillus subtilis Bacillus subtilis IZ = 23.2 mm 21474216
NPT19 Organism Escherichia coli Escherichia coli IZ = 18 mm 21474216
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae IZ = 19.5 mm 21474216
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC50 = 0.48 ug/ml 21669535
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 1.2 ug/ml 21669535
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.56 ug/ml 21741250
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 1.56 ug/ml 21741250
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 3.13 ug/ml 21741250
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.13 ug/ml 21741250
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC50 = 0.42 ug/ml 21856050
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 1.1 ug/ml 21856050
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 21930375
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 21930375
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 128 ug/ml 21930375
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 21930375
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae IZ = 18 mm 22341789
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 9 mm 22341789
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium IZ = 14 mm 22341789
NPT79 Organism Bacillus subtilis Bacillus subtilis IZ = 15 mm 22341789
NPT19 Organism Escherichia coli Escherichia coli IZ = 13 mm 22341789
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 21 mm 22341789
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.13 ug/ml 22710102
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 3.13 ug/ml 22710102
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 1.56 ug/ml 22710102
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.56 ug/ml 22710102
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC90 = 3125 nM 23064162
NPT66 Individual Protein Acetylcholinesterase Electrophorus electricus Inhibition = 17.57 % 23062825
NPT67 Individual Protein Cholinesterase Equus caballus Inhibition = -5.91 % 23062825
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 23215246
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 23215246
NPT2 Others Unspecified MIC < 1 ug/ml 23215246
NPT1261 Organism Bacillus thuringiensis Bacillus thuringiensis MIC = 4 ug/ml 23215246
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC < 1 ug/ml 23215246
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 23215246
NPT729 Organism Micrococcus luteus Micrococcus luteus MIC = 32 ug/ml 23215246
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MBC = 16 ug/ml 10.1007/s00044-011-9933-5
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MBC = 12.5 ug/ml 10.1007/s00044-011-9933-5
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC = 48.4 ug/ml 10.1007/s00044-011-9933-5
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC = 47.9 ug/ml 10.1007/s00044-011-9933-5
NPT1863 Organism Staphylococcus saprophyticus Staphylococcus saprophyticus MBC = 40 ug/ml 10.1007/s00044-011-9933-5
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MBC = 25 ug/ml 10.1007/s00044-011-9933-5
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC = 55.1 ug/ml 10.1007/s00044-011-9933-5
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC = 17.9 ug/ml 10.1007/s00044-011-9933-5
NPT19 Organism Escherichia coli Escherichia coli MBC = 85.5 ug/ml 10.1007/s00044-011-9933-5
NPT19 Organism Escherichia coli Escherichia coli MBC = 84.4 ug/ml 10.1007/s00044-011-9933-5
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MBC > 100 ug/ml 10.1007/s00044-011-9933-5
NPT2912 Organism Shigella boydii Shigella boydii IZ = 15 mm 10.1007/s00044-009-9214-8
NPT2912 Organism Shigella boydii Shigella boydii IZ = 16 mm 10.1007/s00044-009-9214-8
NPT2912 Organism Shigella boydii Shigella boydii IZ = 14 mm 10.1007/s00044-009-9214-8
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium IZ = 20 mm 10.1007/s00044-009-9214-8
NPT775 Organism Proteus Proteus IZ = 25 mm 10.1007/s00044-009-9214-8
NPT19 Organism Escherichia coli Escherichia coli IZ = 25 mm 10.1007/s00044-009-9214-8
NPT2911 Organism Pseudomonas putida Pseudomonas putida IZ = 14 mm 10.1007/s00044-009-9214-8
NPT2913 Organism Listeria monocytogenes ATCC 19115 Listeria monocytogenes ATCC 19115 IZ = 15 mm 10.1007/s00044-009-9214-8
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 25 mm 10.1007/s00044-009-9214-8
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 10.1007/s00044-011-9951-3
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC > 256 ug/ml 10.1007/s00044-011-9951-3
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 10.1007/s00044-011-9951-3
NPT2914 Organism Xanthomonas oryzae Xanthomonas oryzae IZ = 0 mm 23229055
NPT2915 Organism Erwinia chrysanthemi Erwinia chrysanthemi IZ = 0 mm 23229055
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 0 mm 23229055
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 10 mm 23229055
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae IZ = 15 mm 23229055
NPT2642 Organism Bacillus pumilus Bacillus pumilus IZ = 0 mm 23229055
NPT1261 Organism Bacillus thuringiensis Bacillus thuringiensis IZ = 15 mm 23229055
NPT1242 Organism Salmonella typhi Salmonella enterica subsp. enterica serovar Typhi IZ = 20 mm 10.1007/s00044-012-0039-5
NPT19 Organism Escherichia coli Escherichia coli IZ = 25 mm 10.1007/s00044-012-0039-5
NPT2913 Organism Listeria monocytogenes ATCC 19115 Listeria monocytogenes ATCC 19115 IZ = 15 mm 10.1007/s00044-012-0039-5
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 25 mm 10.1007/s00044-012-0039-5
NPT2758 Organism Streptomyces alboniger Streptomyces alboniger IZ = 14 mm 10.1584/jpestics.28.183
NPT2759 Organism Streptomyces acidiscabies Streptomyces acidiscabies IZ = 12 mm 10.1584/jpestics.28.183
NPT2759 Organism Streptomyces acidiscabies Streptomyces acidiscabies IZ = 18 mm 10.1584/jpestics.28.183
NPT2760 Organism Streptomyces scabiei Streptomyces scabiei IZ = 13 mm 10.1584/jpestics.28.183
NPT2760 Organism Streptomyces scabiei Streptomyces scabiei IZ = 18 mm 10.1584/jpestics.28.183
NPT2760 Organism Streptomyces scabiei Streptomyces scabiei IZ = 10 mm 10.1584/jpestics.28.183
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 1 ug/ml 23441911
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 23441911
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4 ug/ml 23441911
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 250 ug/ml 23202847
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC = 15.62 ug/ml 23202847
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 500 ug/ml 23202847
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 7.81 ug/ml 23202847
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 23445125
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC99 = 5.4 nM 24900574
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.56 ug/ml 23490159
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 1.56 ug/ml 23490159
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 3.13 ug/ml 23490159
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.13 ug/ml 23490159
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.56 ug/ml 23602519
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 1.56 ug/ml 23602519
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 3.13 ug/ml 23602519
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.13 ug/ml 23602519
NPT2 Others Unspecified MIC = 0.78 ug/ml 23644188
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 3.13 ug/ml 23644188
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 3.13 ug/ml 23644188
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.56 ug/ml 23644188
NPT2 Others Unspecified IC50 = 6300 nM 23770447
NPT79 Organism Bacillus subtilis Bacillus subtilis IC50 = 8.9 ug/ml 23770447
NPT1261 Organism Bacillus thuringiensis Bacillus thuringiensis IC50 = 9.5 ug/ml 23770447
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IC50 = 6.8 ug/ml 23770447
NPT19 Organism Escherichia coli Escherichia coli IC50 = 47.3 ug/ml 23770447
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 1.5 ug/ml 23891164
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 3.5 ug/ml 23891164
NPT2709 Organism Bacillus subtilis subsp. subtilis str. 168 Bacillus subtilis subsp. subtilis str. 168 MBC = 1 ug/ml 23994872
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC = 4 ug/ml 23994872
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 1 ug/ml 23994872
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 23994872
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 23994872
NPT2709 Organism Bacillus subtilis subsp. subtilis str. 168 Bacillus subtilis subsp. subtilis str. 168 MIC = 0.25 ug/ml 23994872
NPT1101 Organism Staphylococcus aureus subsp. aureus RN4220 Staphylococcus aureus subsp. aureus RN4220 MIC = 1 ug/ml 23994872
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 23994872
NPT189 Cell Line Vero Chlorocebus aethiops IC50 > 100 ug/ml 24087924
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 = 1.12 ug/ml 24087924
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 > 25 ug/ml 24087924
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 = 0.76 ug/ml 24087924
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 = 0.72 ug/ml 24087924
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC90 = 0.73 ug/ml 24087924
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC90 = 0.65 ug/ml 24087924
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis IC50 < 1 ug/ml 24168147
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IC50 = 209 ug/ml 24168147
NPT19 Organism Escherichia coli Escherichia coli IC50 < 1 ug/ml 24168147
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis IC50 = 90 ug/ml 24168147
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 128 ug/ml 24251399
NPT2 Others Unspecified MIC = 4 ug/ml 24251399
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.5 ug/ml 24251399
NPT729 Organism Micrococcus luteus Micrococcus luteus MIC = 0.5 ug/ml 24251399
NPT2 Others Unspecified MIC = 0.5 ug/ml 24251399
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 24251399
NPT2 Others Unspecified IC50 = 6700 nM 24594526
NPT2 Others Unspecified IC50 = 3100 nM 24594526
NPT79 Organism Bacillus subtilis Bacillus subtilis IC50 = 8.9 ug/ml 24594526
NPT1261 Organism Bacillus thuringiensis Bacillus thuringiensis IC50 = 9.5 ug/ml 24594526
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IC50 = 6.8 ug/ml 24594526
NPT19 Organism Escherichia coli Escherichia coli IC50 = 47.3 ug/ml 24594526
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC99 = 1.76 nM 10.1039/C3MD00387F
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC < 3.1 uL/ml 621719
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 100 uL/ml 621719
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC < 3.1 uL/ml 621719
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 50 uL/ml 621719
NPT19 Organism Escherichia coli Escherichia coli MIC < 3.1 uL/ml 621719
NPT19 Organism Escherichia coli Escherichia coli MIC = 100 uL/ml 621719
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 50 uL/ml 621719
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 100 uL/ml 621719
NPT2917 Organism Serratia Serratia MIC > 100 uL/ml 621719
NPT2917 Organism Serratia Serratia MIC < 3.1 uL/ml 621719
NPT766 Organism Proteus vulgaris Proteus vulgaris MIC < 3.1 uL/ml 621719
NPT1246 Organism Salmonella Salmonella MIC < 3.1 uL/ml 621719
NPT2918 Organism Erwinia Erwinia MIC < 3.1 uL/ml 621719
NPT2 Others Unspecified MIC = 6.25 uL/ml 621719
NPT19 Organism Escherichia coli Escherichia coli MIC > 128000 nM 25517209
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 240000 nM 25517209
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2800 nM 25517209
NPT1204 Organism Enterococcus faecalis ATCC 29212 Enterococcus faecalis ATCC 29212 MIC = 360000 nM 25517209
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC99 = 7.16 nM 24997576
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC99 = 3.57 nM 24997576
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis FC = 2 24997576
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC99 = 0.89 nM 24997576
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis Ratio = 0.5 24997576
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis Ratio = 0.249 24997576
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis Ratio = 0.497 24997576
NPT314 Organism Bacillus cereus Bacillus cereus MIC = 6.25 ug/ml 25089733
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 25 ug/ml 25238443
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.56 ug/ml 25238443
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC = 3.13 ug/ml 25238443
NPT19 Organism Escherichia coli Escherichia coli MIC < 0.2 ug/ml 25238443
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 50 ug/ml 25238443
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 200 ug/ml 25238443
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC > 200 ug/ml 25238443
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 128 ug/ml 25280369
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 64 ug/ml 25280369
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 25280369
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 25280369
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 25280369
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4 ug/ml 25280369
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 25280369
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC > 128 ug/ml 25280369
NPT1204 Organism Enterococcus faecalis ATCC 29212 Enterococcus faecalis ATCC 29212 MIC = 31 ug/ml 25280369
NPT1261 Organism Bacillus thuringiensis Bacillus thuringiensis IC50 = 9.5 ug/ml 25318998
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IC50 = 6.8 ug/ml 25318998
NPT19 Organism Escherichia coli Escherichia coli IC50 = 46.3 ug/ml 25318998
NPT79 Organism Bacillus subtilis Bacillus subtilis IC50 = 8.9 ug/ml 25318998
NPT2919 Individual Protein 3-oxoacyl-[acyl-carrier-protein] synthase 3 Escherichia coli K-12 IC50 = 6800 nM 25318998
NPT19 Organism Escherichia coli Escherichia coli MBC90 = 31.3 ug/ml 25556094
NPT19 Organism Escherichia coli Escherichia coli MBC50 = 15.6 ug/ml 25556094
NPT19 Organism Escherichia coli Escherichia coli MBC = 7.8 ug/ml 25556094
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 15.6 ug/ml 25556094
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 7.8 ug/ml 25556094
NPT19 Organism Escherichia coli Escherichia coli MIC = 3.9 ug/ml 25556094
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC90 = 7.8 ug/ml 25556094
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC50 = 3.9 ug/ml 25556094
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC = 11.7 ug/ml 25556094
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 = 5.8 ug/ml 25556094
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 2.9 ug/ml 25556094
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2.9 ug/ml 25556094
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 25824664
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 125 ug/ml 25824664
NPT19 Organism Escherichia coli Escherichia coli IZ = 20 mm 25746816
NPT172 Organism Proteus mirabilis Proteus mirabilis IZ = 20 mm 25746816
NPT19 Organism Escherichia coli Escherichia coli MIC < 0.1 ug/ml 25602977
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC < 0.1 ug/ml 25602977
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC < 0.1 ug/ml 25602977
NPT729 Organism Micrococcus luteus Micrococcus luteus MIC = 1 ug/ml 25602977
NPT21 Organism Aspergillus niger Aspergillus niger MIC = 31.3 ug/ml 25602977
NPT330 Organism Trichophyton mentagrophytes Trichophyton mentagrophytes MIC = 7.8 ug/ml 25602977
NPT20 Organism Candida albicans Candida albicans MIC > 62.5 ug/ml 25602977
NPT729 Organism Micrococcus luteus Micrococcus luteus IZ = 16 mm 25958242
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis IZ = 20.5 mm 25958242
NPT175 Organism Enterococcus faecalis Enterococcus faecalis IZ = 17.9 mm 25958242
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 16.3 mm 25958242
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2500 nM 25941556
NPT19 Organism Escherichia coli Escherichia coli MIC = 10000 nM 25941556
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 25646964
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 25646964
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 25646964
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8300 nM 25756503
NPT19 Organism Escherichia coli Escherichia coli MIC = 4350 nM 26318069
NPT1140 Organism Escherichia coli ATCC 8739 Escherichia coli ATCC 8739 MIC = 1260 nM 26318069
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 7160 nM 26318069
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1000 ug/ml 26432604
NPT2 Others Unspecified IZ = 30 mm 26584881
NPT2 Others Unspecified IZ = 22 mm 26584881
NPT2 Others Unspecified IZ = 6 mm 26584881
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 0 mm 26584881
NPT766 Organism Proteus vulgaris Proteus vulgaris MIC = 5 ug/ml 26546212
NPT2920 Organism Pseudomonas syringae Pseudomonas syringae MIC = 10 ug/ml 26546212
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 5 ug/ml 26546212
NPT19 Organism Escherichia coli Escherichia coli MIC = 5 ug/ml 26546212
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 80 ug/ml 26546212
NPT2709 Organism Bacillus subtilis subsp. subtilis str. 168 Bacillus subtilis subsp. subtilis str. 168 MIC = 2 ug/ml 26592740
NPT2913 Organism Listeria monocytogenes ATCC 19115 Listeria monocytogenes ATCC 19115 MIC = 128 ug/ml 26592740
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 128 ug/ml 26592740
NPT1107 Organism Mycobacterium smegmatis str. MC2 155 Mycobacterium smegmatis str. MC2 155 MIC <= 0.25 ug/ml 26592740
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 128 ug/ml 26592740
NPT1277 Organism Staphylococcus epidermidis ATCC 12228 Staphylococcus epidermidis ATCC 12228 MIC = 1 ug/ml 26592740
NPT1605 Organism Enterococcus Enterococcus MIC > 128 ug/ml 26592740
NPT2 Others Unspecified MIC = 4 ug/ml 26592740
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 2 ug/ml 26592740
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 26592740
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 26592740
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 26592740
NPT1190 Organism Salmonella enterica Salmonella enterica MIC = 16 ug/ml 26592740
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 128 ug/ml 26617967
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC > 150 ug/ml 26617967
NPT564 Organism Listeria monocytogenes Listeria monocytogenes MIC = 4.7 ug/ml 26617967
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.5 ug/ml 26617967
NPT314 Organism Bacillus cereus Bacillus cereus MIC = 9.4 ug/ml 26617967
NPT2 Others Unspecified MIC > 128 ug/ml 26617967
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC = 9.4 ug/ml 26617967
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 37.5 ug/ml 26617967
NPT1107 Organism Mycobacterium smegmatis str. MC2 155 Mycobacterium smegmatis str. MC2 155 MIC > 128 ug/ml 26617967
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 26898336
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC = 3.9 ug/ml 26898336
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 26898336
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 3.9 ug/ml 26898336
NPT1108 Organism Mycobacterium bovis BCG Mycobacterium bovis BCG MIC = 0.6 ug/ml 26900657
NPT1108 Organism Mycobacterium bovis BCG Mycobacterium bovis BCG Ratio = 1 26900657
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.67 ug/ml 26927426
NPT19 Organism Escherichia coli Escherichia coli IC50 = 1.62 ug/ml 26927426
NPT2921 Organism Pseudomonas Pseudomonas MIC = 0.012 ug/ml 26927426
NPT2921 Organism Pseudomonas Pseudomonas IC50 = 0.49 ug/ml 26927426
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 26927426
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IC50 > 30 ug/ml 26927426
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.25 ug/ml 26927426
NPT79 Organism Bacillus subtilis Bacillus subtilis IC50 = 1.35 ug/ml 26927426
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.62 ug/ml 26920799
NPT19 Organism Escherichia coli Escherichia coli IC50 = 0.13 ug/ml 26920799
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 0.49 ug/ml 26920799
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens IC50 = 0.014 ug/ml 26920799
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 33 ug/ml 26920799
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IC50 > 30 ug/ml 26920799
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 1.35 ug/ml 26920799
NPT79 Organism Bacillus subtilis Bacillus subtilis IC50 = 0.37 ug/ml 26920799
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.62 ug/ml 27013391
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 0.49 ug/ml 27013391
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 30 ug/ml 27013391
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 1.35 ug/ml 27013391
NPT1101 Organism Staphylococcus aureus subsp. aureus RN4220 Staphylococcus aureus subsp. aureus RN4220 MIC99 = 8 ug/ml 26964758
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC99 = 32 ug/ml 26964758
NPT19 Organism Escherichia coli Escherichia coli MIC99 = 8 ug/ml 26964758
NPT1531 Organism Enterococcus faecium Enterococcus faecium EC50 > 100000 nM 27184767
NPT2922 Organism Staphylococcus aureus subsp. aureus Staphylococcus aureus subsp. aureus EC50 = 8200 nM 27184767
NPT2922 Organism Staphylococcus aureus subsp. aureus Staphylococcus aureus subsp. aureus EC50 > 100000 nM 27184767
NPT2923 Organism Klebsiella pneumoniae subsp. pneumoniae Klebsiella pneumoniae subsp. pneumoniae EC50 = 45000 nM 27184767
NPT2 Others Unspecified EC50 = 16000 nM 27184767
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa EC50 = 25000 nM 27184767
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae EC50 = 37000 nM 27184767
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.95 ug/ml 27259400
NPT19 Organism Escherichia coli Escherichia coli MIC = 7.81 ug/ml 27259400
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC = 1.95 ug/ml 27259400
NPT2 Others Unspecified MBC = 7.81 ug/ml 27259400

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC43850 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
1.0 High Similarity NPC314007
1.0 High Similarity NPC477060
1.0 High Similarity NPC123746
1.0 High Similarity NPC314408
0.9759 High Similarity NPC176381
0.9759 High Similarity NPC195969
0.9518 High Similarity NPC214376
0.9419 High Similarity NPC315334
0.9398 High Similarity NPC313552
0.9383 High Similarity NPC263058
0.9259 High Similarity NPC315969
0.9205 High Similarity NPC330590
0.8804 High Similarity NPC315036
0.878 High Similarity NPC318258
0.8602 High Similarity NPC56298
0.8602 High Similarity NPC471628
0.7778 Intermediate Similarity NPC221148
0.767 Intermediate Similarity NPC57436
0.767 Intermediate Similarity NPC121479
0.7609 Intermediate Similarity NPC470282
0.7586 Intermediate Similarity NPC316807
0.7531 Intermediate Similarity NPC291650
0.7531 Intermediate Similarity NPC322801
0.7531 Intermediate Similarity NPC129100
0.75 Intermediate Similarity NPC70574
0.75 Intermediate Similarity NPC306838
0.7453 Intermediate Similarity NPC241597
0.7386 Intermediate Similarity NPC98750
0.7333 Intermediate Similarity NPC271772
0.7333 Intermediate Similarity NPC36927
0.7113 Intermediate Similarity NPC328646
0.7111 Intermediate Similarity NPC83248
0.7111 Intermediate Similarity NPC100204
0.7065 Intermediate Similarity NPC165119
0.7033 Intermediate Similarity NPC471420
0.693 Remote Similarity NPC94319
0.6915 Remote Similarity NPC253975
0.6915 Remote Similarity NPC192025
0.6915 Remote Similarity NPC125253
0.6842 Remote Similarity NPC83839
0.6813 Remote Similarity NPC150557
0.6804 Remote Similarity NPC470284
0.6667 Remote Similarity NPC327753
0.6667 Remote Similarity NPC327486
0.6667 Remote Similarity NPC223174
0.6574 Remote Similarity NPC317534
0.6471 Remote Similarity NPC470283
0.6436 Remote Similarity NPC208537
0.6436 Remote Similarity NPC270005
0.6404 Remote Similarity NPC313813
0.6356 Remote Similarity NPC20035
0.6344 Remote Similarity NPC314772
0.6344 Remote Similarity NPC314968
0.6265 Remote Similarity NPC317023
0.6262 Remote Similarity NPC188453
0.6262 Remote Similarity NPC42320
0.6224 Remote Similarity NPC476523
0.6145 Remote Similarity NPC472025
0.6129 Remote Similarity NPC244539
0.6126 Remote Similarity NPC59589
0.6071 Remote Similarity NPC290179
0.6071 Remote Similarity NPC34877
0.6064 Remote Similarity NPC313762
0.6049 Remote Similarity NPC242073
0.6049 Remote Similarity NPC269166
0.6049 Remote Similarity NPC165198
0.6049 Remote Similarity NPC107914
0.6049 Remote Similarity NPC246558
0.6049 Remote Similarity NPC89145
0.6049 Remote Similarity NPC67660
0.6049 Remote Similarity NPC145112
0.6049 Remote Similarity NPC58629
0.6049 Remote Similarity NPC157514
0.6 Remote Similarity NPC314413
0.6 Remote Similarity NPC239705
0.6 Remote Similarity NPC314306
0.6 Remote Similarity NPC314398
0.5984 Remote Similarity NPC68327
0.5976 Remote Similarity NPC303727
0.5946 Remote Similarity NPC92874
0.5946 Remote Similarity NPC62845
0.5946 Remote Similarity NPC166242
0.5946 Remote Similarity NPC189854
0.5946 Remote Similarity NPC322449
0.593 Remote Similarity NPC477753
0.593 Remote Similarity NPC477755
0.593 Remote Similarity NPC477757
0.593 Remote Similarity NPC477762
0.593 Remote Similarity NPC477750
0.593 Remote Similarity NPC477763
0.5909 Remote Similarity NPC6848
0.5893 Remote Similarity NPC325900
0.5893 Remote Similarity NPC10897
0.587 Remote Similarity NPC476694
0.587 Remote Similarity NPC476695
0.587 Remote Similarity NPC476696
0.5862 Remote Similarity NPC17455
0.5843 Remote Similarity NPC315980
0.582 Remote Similarity NPC139857
0.581 Remote Similarity NPC61894
0.581 Remote Similarity NPC475603
0.5806 Remote Similarity NPC474468
0.5802 Remote Similarity NPC326533
0.5752 Remote Similarity NPC475918
0.5726 Remote Similarity NPC75839
0.5714 Remote Similarity NPC471418
0.5682 Remote Similarity NPC218150
0.5682 Remote Similarity NPC22774
0.5682 Remote Similarity NPC69669
0.5682 Remote Similarity NPC2432
0.5682 Remote Similarity NPC306462
0.5682 Remote Similarity NPC150680
0.5667 Remote Similarity NPC471760
0.5667 Remote Similarity NPC12040
0.5667 Remote Similarity NPC471761
0.5667 Remote Similarity NPC190418
0.5667 Remote Similarity NPC76881
0.5663 Remote Similarity NPC323361
0.5663 Remote Similarity NPC130683
0.5652 Remote Similarity NPC67099
0.5652 Remote Similarity NPC268922
0.5652 Remote Similarity NPC250619
0.5647 Remote Similarity NPC148424
0.5647 Remote Similarity NPC8979
0.5632 Remote Similarity NPC143326
0.561 Remote Similarity NPC233726
0.561 Remote Similarity NPC23134
0.561 Remote Similarity NPC124963
0.5604 Remote Similarity NPC477752
0.5604 Remote Similarity NPC477756
0.5604 Remote Similarity NPC477764
0.5604 Remote Similarity NPC477751

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC43850 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
1.0 High Similarity NPD3203 Approved
1.0 High Similarity NPD3209 Approved
1.0 High Similarity NPD3201 Approved
1.0 High Similarity NPD3208 Approved
1.0 High Similarity NPD3207 Approved
1.0 High Similarity NPD3202 Approved
0.9877 High Similarity NPD3200 Clinical (unspecified phase)
0.9759 High Similarity NPD5797 Approved
0.9759 High Similarity NPD5796 Clinical (unspecified phase)
0.9759 High Similarity NPD5798 Approved
0.9759 High Similarity NPD5794 Approved
0.9759 High Similarity NPD5795 Approved
0.9518 High Similarity NPD2698 Approved
0.9205 High Similarity NPD5381 Approved
0.9205 High Similarity NPD5377 Approved
0.9205 High Similarity NPD5378 Approved
0.8791 High Similarity NPD4282 Approved
0.8602 High Similarity NPD4836 Approved
0.8602 High Similarity NPD4837 Approved
0.8602 High Similarity NPD4838 Approved
0.8602 High Similarity NPD4835 Approved
0.8351 Intermediate Similarity NPD5376 Approved
0.7778 Intermediate Similarity NPD1449 Approved
0.7778 Intermediate Similarity NPD1450 Approved
0.767 Intermediate Similarity NPD4833 Approved
0.767 Intermediate Similarity NPD35 Approved
0.7531 Intermediate Similarity NPD9031 Approved
0.7531 Intermediate Similarity NPD9033 Approved
0.7531 Intermediate Similarity NPD9030 Approved
0.7531 Intermediate Similarity NPD9032 Approved
0.7453 Intermediate Similarity NPD3731 Phase 3
0.7429 Intermediate Similarity NPD2690 Discontinued
0.7353 Intermediate Similarity NPD2700 Approved
0.7347 Intermediate Similarity NPD6428 Approved
0.7315 Intermediate Similarity NPD4830 Approved
0.7315 Intermediate Similarity NPD4831 Approved
0.7315 Intermediate Similarity NPD4832 Approved
0.7209 Intermediate Similarity NPD67 Phase 2
0.7209 Intermediate Similarity NPD9034 Approved
0.708 Intermediate Similarity NPD6436 Phase 3
0.693 Remote Similarity NPD4828 Approved
0.693 Remote Similarity NPD4826 Approved
0.693 Remote Similarity NPD4827 Approved
0.6923 Remote Similarity NPD8045 Clinical (unspecified phase)
0.6757 Remote Similarity NPD3204 Clinical (unspecified phase)
0.6735 Remote Similarity NPD3716 Discontinued
0.6667 Remote Similarity NPD9445 Approved
0.6606 Remote Similarity NPD6941 Approved
0.6602 Remote Similarity NPD881 Approved
0.6355 Remote Similarity NPD7140 Approved
0.6355 Remote Similarity NPD7139 Approved
0.6355 Remote Similarity NPD7141 Clinical (unspecified phase)
0.6344 Remote Similarity NPD9435 Approved
0.6344 Remote Similarity NPD9434 Approved
0.625 Remote Similarity NPD8087 Discontinued
0.6214 Remote Similarity NPD1446 Phase 3
0.6214 Remote Similarity NPD1447 Phase 3
0.62 Remote Similarity NPD4759 Clinical (unspecified phase)
0.6118 Remote Similarity NPD6123 Approved
0.6075 Remote Similarity NPD2255 Approved
0.605 Remote Similarity NPD8345 Approved
0.605 Remote Similarity NPD8346 Approved
0.605 Remote Similarity NPD8347 Approved
0.6049 Remote Similarity NPD893 Approved
0.6049 Remote Similarity NPD892 Phase 3
0.6049 Remote Similarity NPD891 Phase 3
0.6049 Remote Similarity NPD890 Clinical (unspecified phase)
0.6049 Remote Similarity NPD888 Phase 3
0.6 Remote Similarity NPD6430 Approved
0.6 Remote Similarity NPD6429 Approved
0.5926 Remote Similarity NPD2269 Approved
0.5895 Remote Similarity NPD372 Clinical (unspecified phase)
0.5854 Remote Similarity NPD591 Approved
0.5854 Remote Similarity NPD577 Phase 3
0.5842 Remote Similarity NPD394 Phase 3
0.5841 Remote Similarity NPD8307 Discontinued
0.5802 Remote Similarity NPD905 Approved
0.5802 Remote Similarity NPD904 Phase 3
0.5789 Remote Similarity NPD8174 Phase 2
0.5745 Remote Similarity NPD389 Phase 3
0.5743 Remote Similarity NPD361 Discontinued
0.5702 Remote Similarity NPD8140 Approved
0.5682 Remote Similarity NPD9027 Phase 3
0.5682 Remote Similarity NPD9026 Phase 2
0.5682 Remote Similarity NPD9028 Phase 2
0.5682 Remote Similarity NPD9029 Phase 3
0.5663 Remote Similarity NPD894 Approved
0.5663 Remote Similarity NPD889 Approved
0.5663 Remote Similarity NPD887 Approved
0.5663 Remote Similarity NPD895 Approved

Structure

External Identifiers

PubChem CID   6032
ChEMBL   CHEMBL1384
ZINC  

Physicochemical Properties

Molecular Weight:  484.24
ALogP:  -7.4937
MLogP:  1.79
XLogP:  -5.486
# Rotatable Bonds:  17
Polar Surface Area:  282.61
# H-Bond Aceptor:  15
# H-Bond Donor:  11
# Rings:  3
# Heavy Atoms:  33

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