Natural Product: NPC314408

Natural Product ID:  NPC314408
Common Name:   Tobramycin
IUPAC Name:   (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
Synonyms:   47663; Aktob; Bethkis; Bramitob; Nebcin; Nebicin; Nebramycin; Nebramycin Factor 6; Nebris; Obramycin; Tobi; Tobradex; Tobradex St; Tobralex; Tobramycin; Tobravisc; Tobrex; Tymbrineb; Vantobra
Molecular Formula:   C18H37N5O9
Standard InCHIKey:  NLVFBUXFDBBNBW-PBSUHMDJSA-N
Standard InCHI:  InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1
Canonical SMILES:  NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@H]([C@@H]([C@H]2O)O[C@H]2O[C@H](CO)[C@H]([C@@H]([C@H]2O)N)O)N)[C@@H](C[C@@H]1O)N
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   BGC0000719;BGC0000720;BGC0000721 ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO9026 Streptoalloteichus tenebrarius Species Pseudonocardiaceae Bacteria StreptomeDB*
NPO9026.2 Streptomyces tenebrarius h6 Subspecies Pseudonocardiaceae Bacteria StreptomeDB*
NPO21901.1 Streptomyces cremeus 2242 Subspecies Streptomycetaceae Bacteria StreptomeDB*
NPO9026.1 Streptomyces tenebrarius atcc 17920 Subspecies Pseudonocardiaceae Bacteria StreptomeDB*
NPO9026.3 Streptomyces tenebrarius ifo 13396 Subspecies Pseudonocardiaceae Bacteria StreptomeDB*
NPO15128 Streptomyces coeruleoaurantiacus Species Streptomycetaceae Bacteria StreptomeDB*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT317 Uncleic Acid Nucleic Acid MIC = 10000 nM 9457241
NPT317 Uncleic Acid Nucleic Acid Kd = 2070 nM 11814798
NPT317 Uncleic Acid Nucleic Acid Kd = 2040 nM 11814798
NPT317 Uncleic Acid Nucleic Acid Kd = 2120 nM 11814798
NPT317 Uncleic Acid Nucleic Acid Kd = 680 nM 11814798
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC = 32 ug/ml 11425542
NPT4977 Individual Protein Human immunodeficiency virus type 1 REV Human immunodeficiency virus 1 Kd = 4110 nM 11354359
NPT317 Uncleic Acid Nucleic Acid Kd = 2110 nM 10915059
NPT317 Uncleic Acid Nucleic Acid Kd = 1680 nM 10915059
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.03 ug/ml 3701779
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 3701779
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 32 ug/ml 3701779
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.13 ug/ml 3701779
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.13 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 3701779
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 3701779
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.25 ug/ml 3701779
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.5 ug/ml 3701779
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1 ug/ml 3701779
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 16 ug/ml 3701779
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.06 ug/ml 3701779
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC = 0.5 ug/ml 3701779
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC = 0.13 ug/ml 3701779
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC = 32 ug/ml 3701779
NPT2895 Organism Providencia stuartii Providencia stuartii MIC = 2 ug/ml 3701779
NPT2895 Organism Providencia stuartii Providencia stuartii MIC = 16 ug/ml 3701779
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 2 ug/ml 3701779
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.06 ug/ml 3701779
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.13 ug/ml 3701779
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 125 ug/ml 3701779
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 125 ug/ml 3701779
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 3701779
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 3701779
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.5 ug/ml 15203152
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC > 32 ug/ml 15203152
NPT19 Organism Escherichia coli Escherichia coli MIC > 1 ug/ml 15203152
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 15203152
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 64 ug/ml 15203152
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 64 ug/ml 15203152
NPT2 Others Unspecified Kd = 1680 nM 11677142
NPT2 Others Unspecified Kd = 3260 nM 12127547
NPT2 Others Unspecified Kd = 430 nM 12127547
NPT2 Others Unspecified Kd = 2910 nM 12127547
NPT2 Others Unspecified Kd = 5370 nM 12127547
NPT4383 Uncleic Acid Ribosomal RNA A-site Kd = 1500 nM 11206440
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 15808482
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 50 ug/ml 15808482
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 100 ug/ml 15808482
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 6.3 ug/ml 15808482
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 15808482
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 15808482
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 15808482
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 32 ug/ml 15808482
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.25 ug/ml 15808482
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 32 ug/ml 15808482
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 15808482
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 64 ug/ml 15808482
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 200 ug/ml 15808482
NPT79 Organism Bacillus subtilis Bacillus subtilis Kd = 38000 nM 15808490
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 32 ug/ml 16202590
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 16202590
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 16202590
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 16202590
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.25 ug/ml 16202590
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 17088477
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 17088477
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC = 32 ug/ml 17088477
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 67.5 % 17158943
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 36.9 % 17158943
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 83.8 % 17158943
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 17088479
NPT19 Organism Escherichia coli Escherichia coli MIC = 6 ug/ml 17088479
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 256 ug/ml 17158944
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 17158944
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.06 ug/ml 17158944
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 17194835
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 17194835
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.25 ug/ml 17194835
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 17194835
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 17194835
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 17194835
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 17261621
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 64 ug/ml 17261621
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 Activity = 0.4 17353241
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 Activity = 1.51 17353241
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 Activity = 0.78 17353241
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 Activity = 1.36 17353241
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC50 = 8 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC90 = 16 ug/ml 17353252
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC50 = 16 ug/ml 17353252
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC90 = 32 ug/ml 17353252
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC50 = 16 ug/ml 17353252
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC90 = 64 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC > 128 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 32 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 16 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 8 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 4 ug/ml 17353252
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC = 128 ug/ml 17353252
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC = 64 ug/ml 17353252
NPT19 Organism Escherichia coli Escherichia coli MIC50 > 8 ug/ml 17371815
NPT19 Organism Escherichia coli Escherichia coli MIC90 > 8 ug/ml 17371815
NPT19 Organism Escherichia coli Escherichia coli Activity = 94 % 17371815
NPT19 Organism Escherichia coli Escherichia coli Activity = 95 % 17371815
NPT19 Organism Escherichia coli Escherichia coli MIC50 <= 2 ug/ml 17371815
NPT19 Organism Escherichia coli Escherichia coli Activity = 22 % 17371815
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 32 ug/ml 17404005
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 4 ug/ml 17420207
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 55 % 17420207
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 0.75 ug/ml 17420217
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 17420217
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 3 ug/ml 17420217
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 6 ug/ml 17420217
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 16 ug/ml 17420217
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 8 ug/ml 17420217
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 24 ug/ml 17420217
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.95 ug/ml 17450125
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.62 ug/ml 17450125
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.62 ug/ml 17450125
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 0.31 ug/ml 17450125
NPT1531 Organism Enterococcus faecium Enterococcus faecium MIC > 62.5 ug/ml 17450125
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC > 62.5 ug/ml 17450125
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae Activity = 41.8 % 17452479
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae Activity = 8.5 % 17452479
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1 ug/ml 17470655
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 Mortality = 66.7 % 17470655
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Mortality = 60 % 17470655
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 17470655
NPT19 Organism Escherichia coli Escherichia coli MIC > 512 ug/ml 17470656
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 16 ug/ml 17470660
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 16 ug/ml 17470660
NPT4080 Organism Acinetobacter sp. Acinetobacter sp. MIC = 16 ug/ml 17470660
NPT4080 Organism Acinetobacter sp. Acinetobacter sp. MIC = 8 ug/ml 17470660
NPT2911 Organism Pseudomonas putida Pseudomonas putida MIC > 16 ug/ml 17470660
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 17470660
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 17470660
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.047 ug/ml 17638702
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.125 ug/ml 17638702
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.25 ug/ml 17638702
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.38 ug/ml 17638702
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.5 ug/ml 17638702
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1 ug/ml 17638702
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1.5 ug/ml 17638702
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC >= 2048 ug/ml 17502406
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 1 ug/ml 17682106
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 > 64 ug/ml 17682106
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 0.12 ug/ml 17682106
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.5 ug/ml 17682106
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 17682106
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 17682106
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 64 ug/ml 17682106
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 17682106
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 17682106
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 17682106
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 21.7 % 17682106
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 77.5 % 17682106
NPT317 Uncleic Acid Nucleic Acid Kd = 80 nM 19445516
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 17724159
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 17724159
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 512 ug/ml 17785513
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC >= 256 ug/ml 17785513
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 32 ug/ml 17938184
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 17938184
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 17938184
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 17938184
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC = 0.25 ug/ml 17938184
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 256 ug/ml 17938181
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 44 % 17938181
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 9 % 17938181
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 64 ug/ml 17938181
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.75 ug/ml 17938181
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.38 ug/ml 17938181
NPT19 Organism Escherichia coli Escherichia coli MIC = 6 ug/ml 17938181
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 17875999
NPT19 Organism Escherichia coli Escherichia coli MIC = 128 ug/ml 17875999
NPT19 Organism Escherichia coli Escherichia coli MIC <= 0.06 ug/ml 17875999
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.13 ug/ml 17875999
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.25 ug/ml 19349095
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 19349095
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 19349095
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 0.5 ug/ml 20000576
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 1 ug/ml 20000576
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 20000576
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 20000576
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 20000576
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 20000576
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 20000576
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 20000576
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 20000576
NPT5774 Organism Citrobacter amalonaticus Citrobacter amalonaticus MIC > 128 ug/ml 20000576
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 20000576
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC > 128 ug/ml 20000576
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.5 ug/ml 20000576
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC < 0.25 ug/ml 20000576
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 6250 nM 20044260
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 25000 nM 20044260
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 200000 nM 20044260
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 400000 nM 20044260
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 1.07 umol/ml 20207052
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 0.53 umol/ml 20207052
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 2.14 umol/ml 20207052
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.25 ug/ml 19858254
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.125 ug/ml 19858254
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 19884373
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 0.75 ug/ml 19884373
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 16 ug/ml 19884373
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 1 ug/ml 19884373
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 1.5 ug/ml 19884373
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 2 ug/ml 19884373
NPT2 Others Unspecified MIC = 64 ug/ml 19884373
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 12 ug/ml 19884373
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 96 ug/ml 19884373
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.125 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 2 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 128 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 1 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 32 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 128 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 256 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 64 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 4 ug/ml 19917762
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 2 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 2 log10CFU/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 2.7 log10CFU/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2.2 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 3 log10CFU/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 3.7 log10CFU/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 4 log10CFU/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 32 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 32 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 19805554
NPT1264 Organism Burkholderia cepacia Burkholderia cepacia MIC50 > 32 ug/ml 19805554
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 > 32 ug/ml 19805554
NPT2 Others Unspecified MIC50 > 32 ug/ml 19805554
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 > 128 ug/ml 19805554
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 0.125 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.25 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 > 32 ug/ml 19805554
NPT1264 Organism Burkholderia cepacia Burkholderia cepacia MIC90 > 32 ug/ml 19805554
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 > 32 ug/ml 19805554
NPT2 Others Unspecified MIC90 > 32 ug/ml 19805554
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 > 128 ug/ml 19805554
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 > 32 ug/ml 19805554
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 33.9 % 19933793
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 19884381
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 19933793
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 19933793
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC < 0.12 ug/ml 19933793
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 19933793
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 64 ug/ml 19933793
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 19933793
NPT19 Organism Escherichia coli Escherichia coli Activity = 69 % 20047913
NPT19 Organism Escherichia coli Escherichia coli Activity = 93 % 20047913
NPT19 Organism Escherichia coli Escherichia coli Activity = 49 % 20047913
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium EC50 = 1 ug/ml 18172002
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium EC50 = 19 ug/ml 18172002
NPT2 Others Unspecified EC50 = 2.5 ug/ml 18172002
NPT2 Others Unspecified EC50 = 75 ug/ml 18172002
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC = 4 ug/ml 18172002
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC = 125 ug/ml 18172002
NPT2 Others Unspecified MIC = 8 ug/ml 18172002
NPT2 Others Unspecified MIC = 250 ug/ml 18172002
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 18285488
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 18285488
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC >= 16 ug/ml 18426899
NPT19 Organism Escherichia coli Escherichia coli MIC >= 16 ug/ml 18426899
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 18426899
NPT19 Organism Escherichia coli Escherichia coli MIC <= 1 ug/ml 18426899
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 20145089
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 20145089
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 20145089
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.25 ug/ml 20194693
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 20194693
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 20194693
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 20194693
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 20194693
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 20194693
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 20194693
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 20194693
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC <= 0.12 ug/ml 20194693
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 32 ug/ml 20194693
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ < 20 mm 18180356
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 2 ug/ml 18180356
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 18180356
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1 ug/ml 18180356
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 18180356
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 18195064
NPT19 Organism Escherichia coli Escherichia coli MIC >= 128 ug/ml 18195064
NPT5768 Organism Acinetobacter pittii Acinetobacter pittii MIC >= 0.5 ug/ml 20368407
NPT5768 Organism Acinetobacter pittii Acinetobacter pittii MIC50 = 8 ug/ml 20368407
NPT5768 Organism Acinetobacter pittii Acinetobacter pittii MIC90 >= 16 ug/ml 20368407
NPT5768 Organism Acinetobacter pittii Acinetobacter pittii Activity = 42.1 % 20368407
NPT4080 Organism Acinetobacter sp. Acinetobacter sp. Activity = 66 % 20194701
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC > 1024 ug/ml 20308368
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC = 64 ug/ml 20308368
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC = 32 ug/ml 20308368
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 18644957
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 48 ug/ml 18644957
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 18644957
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 18644957
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 18644958
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 18644958
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.12 ug/ml 18644958
NPT19 Organism Escherichia coli Escherichia coli MIC > 8 ug/ml 19001117
NPT19 Organism Escherichia coli Escherichia coli MIC <= 2 ug/ml 19001117
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.2 ug/ml 18694947
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.4 ug/ml 18694947
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.2 ug/ml 18694947
NPT2 Others Unspecified Activity = 56 % 20404121
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 18838598
NPT19 Organism Escherichia coli Escherichia coli MIC = 3 ug/ml 18838598
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.19 ug/ml 18838598
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 18838598
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 18838598
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.38 ug/ml 18838598
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 8 ug/ml 18852270
NPT2911 Organism Pseudomonas putida Pseudomonas putida MIC > 8 ug/ml 18852270
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC50 = 8 ug/ml 18725441
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC50 = 4 ug/ml 18725441
NPT2 Others Unspecified MIC50 = 4 ug/ml 18725441
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC50 = 16 ug/ml 18725441
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC90 = 16 ug/ml 18725441
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC90 = 16 ug/ml 18725441
NPT2 Others Unspecified MIC90 = 8 ug/ml 18725441
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC90 = 32 ug/ml 18725441
NPT2 Others Unspecified MIC = 1 ug/ml 18725441
NPT5311 Organism Mycobacterium mageritense Mycobacterium mageritense MIC = 8 ug/ml 18725441
NPT2 Others Unspecified MIC = 4 ug/ml 18725441
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC <= 0.03 ug/ml 18725441
NPT2 Others Unspecified MIC = 0.5 ug/ml 18725441
NPT2 Others Unspecified MIC = 8 ug/ml 18725441
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC <= 1 ug/ml 20498315
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 20498315
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 20498315
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC >= 16 ug/ml 20498315
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 Activity = 20 mg.min/L 18195062
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 FC = 1.5 18195062
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 FC = 0.9 18195062
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 FC = 0.2 18195062
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 Activity = 70 % 18195062
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 Activity = 30 mg.min/L 18195062
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 Activity = 1000 mg.min/L 18195062
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 Ratio = 33 18195062
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.5 ug/ml 18474583
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.25 ug/ml 18474583
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 18474583
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.12 ug/ml 18474583
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 18474583
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 50 ug/ml 18285485
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 240 ug/ml 18285485
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 256 ug/ml 18362195
NPT5768 Organism Acinetobacter pittii Acinetobacter pittii MIC = 0.25 ug/ml 18505859
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 64 ug/ml 18505859
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 64 ug/ml 18519712
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 18519714
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 18519714
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 18519714
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 19015360
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.25 ug/ml 19015360
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC = 0.5 ug/ml 19015360
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 19015360
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 19015360
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml 19015360
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 8 ug/ml 19015360
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 19015360
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC = 4 ug/ml 19015360
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 32 ug/ml 19015360
NPT19 Organism Escherichia coli Escherichia coli MIC90 > 32 ug/ml 19015360
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 32 ug/ml 19015360
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 > 32 ug/ml 19015360
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC50 = 8 ug/ml 19015360
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC90 > 32 ug/ml 19015360
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 16 ug/ml 19015360
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 16 ug/ml 19015360
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 19001116
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 19001116
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 19001116
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 19001116
NPT2 Others Unspecified MIC = 2 ug/ml 19015330
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 0.25 ug/ml 18725436
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4 ug/ml 18725436
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 18725436
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 16 ug/ml 19114677
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 19223629
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 19223629
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 256 ug/ml 19223629
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 FC = 760 19307375
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 FC = 3300 19307375
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC = 1.5 ug/ml 19307375
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC = 2 ug/ml 19307375
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 19349516
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.125 ug/ml 19349516
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 19349516
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1.5 ug/ml 19332676
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1.75 ug/ml 19332676
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 2 ug/ml 19332676
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 6 ug/ml 19332676
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 3.75 ug/ml 19332676
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 3.5 ug/ml 19332676
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.9 ug/ml 19332676
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1.06 ug/ml 19332676
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1.37 ug/ml 19332676
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1.19 ug/ml 19332676
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1.25 ug/ml 19332676
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 1 ug/ml 19364869
NPT19 Organism Escherichia coli Escherichia coli Activity = 50 % 19364876
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 19258280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 19258280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 19258280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 19258280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 19258280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 19258280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.25 ug/ml 19258280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.06 ug/ml 19258280
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.5 ug/ml 19258280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa FC >= 4 19258280
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 19289526
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 2 ug/ml 19289526
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 19289526
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 19289526
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 19289526
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 16 ug/ml 19289526
NPT19 Organism Escherichia coli Escherichia coli MIC > 16 ug/ml 19289526
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 16 ug/ml 19289526
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 = 1 ug/ml 19506065
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 0.5 ug/ml 19506065
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 68.4 % 19506065
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.12 ug/ml 19506065
NPT564 Organism Listeria monocytogenes Listeria monocytogenes MIC90 = 0.12 ug/ml 19506065
NPT564 Organism Listeria monocytogenes Listeria monocytogenes MIC50 = 0.12 ug/ml 19506065
NPT564 Organism Listeria monocytogenes Listeria monocytogenes MIC <= 0.06 ug/ml 19506065
NPT1531 Organism Enterococcus faecium Enterococcus faecium MIC90 > 128 ug/ml 19506065
NPT1531 Organism Enterococcus faecium Enterococcus faecium MIC50 > 128 ug/ml 19506065
NPT1531 Organism Enterococcus faecium Enterococcus faecium MIC = 2 ug/ml 19506065
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC90 > 128 ug/ml 19506065
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC50 = 16 ug/ml 19506065
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 2 ug/ml 19506065
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.25 ug/ml 19506065
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 27.3 % 19506065
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 1 ug/ml 19506065
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 > 32 ug/ml 19506065
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC <= 0.008 ug/ml 19506065
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis Activity = 33.3 % 19506065
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC50 = 0.03 ug/ml 19506065
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 0.06 ug/ml 19506065
NPT1477 Organism Staphylococcus haemolyticus Staphylococcus haemolyticus MIC = 0.015 ug/ml 19506065
NPT4025 Organism Staphylococcus hominis Staphylococcus hominis MIC = 0.015 ug/ml 19506065
NPT4840 Organism Staphylococcus lugdunensis Staphylococcus lugdunensis MIC = 0.03 ug/ml 19506065
NPT1863 Organism Staphylococcus saprophyticus Staphylococcus saprophyticus MIC <= 0.008 ug/ml 19506065
NPT5312 Organism Staphylococcus warneri Staphylococcus warneri MIC = 0.015 ug/ml 19506065
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.25 ug/ml 19752280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 19752280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 19752280
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 19752280
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC50 = 2 ug/ml 19506065
NPT1477 Organism Staphylococcus haemolyticus Staphylococcus haemolyticus MIC50 = 2 ug/ml 19506065
NPT4025 Organism Staphylococcus hominis Staphylococcus hominis MIC50 = 16 ug/ml 19506065
NPT4840 Organism Staphylococcus lugdunensis Staphylococcus lugdunensis MIC50 = 0.12 ug/ml 19506065
NPT1863 Organism Staphylococcus saprophyticus Staphylococcus saprophyticus MIC50 = 0.015 ug/ml 19506065
NPT5312 Organism Staphylococcus warneri Staphylococcus warneri MIC50 = 0.06 ug/ml 19506065
NPT1477 Organism Staphylococcus haemolyticus Staphylococcus haemolyticus MIC90 = 32 ug/ml 19506065
NPT4025 Organism Staphylococcus hominis Staphylococcus hominis MIC90 = 32 ug/ml 19506065
NPT4840 Organism Staphylococcus lugdunensis Staphylococcus lugdunensis MIC90 = 32 ug/ml 19506065
NPT1863 Organism Staphylococcus saprophyticus Staphylococcus saprophyticus MIC90 = 0.06 ug/ml 19506065
NPT5312 Organism Staphylococcus warneri Staphylococcus warneri MIC90 = 8 ug/ml 19506065
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis Activity = 16.7 % 19506065
NPT1477 Organism Staphylococcus haemolyticus Staphylococcus haemolyticus Activity = 26.7 % 19506065
NPT4025 Organism Staphylococcus hominis Staphylococcus hominis Activity = 16 % 19506065
NPT4840 Organism Staphylococcus lugdunensis Staphylococcus lugdunensis Activity = 46.7 % 19506065
NPT1863 Organism Staphylococcus saprophyticus Staphylococcus saprophyticus Activity = 54.5 % 19506065
NPT5312 Organism Staphylococcus warneri Staphylococcus warneri Activity = 34 % 19506065
NPT2710 Organism Streptococcus agalactiae Streptococcus agalactiae MIC = 0.015 ug/ml 19506065
NPT2 Others Unspecified MIC = 0.008 ug/ml 19506065
NPT3893 Organism Streptococcus sp. Streptococcus sp. MIC = 0.008 ug/ml 19506065
NPT2710 Organism Streptococcus agalactiae Streptococcus agalactiae MIC50 = 0.06 ug/ml 19506065
NPT2 Others Unspecified MIC50 = 0.06 ug/ml 19506065
NPT3893 Organism Streptococcus sp. Streptococcus sp. MIC50 = 0.06 ug/ml 19506065
NPT2710 Organism Streptococcus agalactiae Streptococcus agalactiae MIC90 > 8 ug/ml 19506065
NPT2 Others Unspecified MIC90 > 8 ug/ml 19506065
NPT3893 Organism Streptococcus sp. Streptococcus sp. MIC90 > 8 ug/ml 19506065
NPT2710 Organism Streptococcus agalactiae Streptococcus agalactiae Activity = 73 % 19506065
NPT2 Others Unspecified Activity = 74 % 19506065
NPT3893 Organism Streptococcus sp. Streptococcus sp. Activity = 74 % 19506065
NPT1118 Organism Streptococcus pneumoniae Streptococcus pneumoniae MIC = 4 ug/ml 19506065
NPT1118 Organism Streptococcus pneumoniae Streptococcus pneumoniae MIC = 1 ug/ml 19506065
NPT1118 Organism Streptococcus pneumoniae Streptococcus pneumoniae MIC50 = 8 ug/ml 19506065
NPT1118 Organism Streptococcus pneumoniae Streptococcus pneumoniae MIC90 = 16 ug/ml 19506065
NPT1228 Organism Streptococcus pyogenes Streptococcus pyogenes MIC = 4 ug/ml 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 48 ug/ml 19770278
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 19770278
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1 ug/ml 19770278
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 12 ug/ml 19770278
NPT2 Others Unspecified MIC = 0.5 ug/ml 19506065
NPT2904 Organism Streptococcus equinus Streptococcus equinus MIC = 0.008 ug/ml 19506065
NPT5314 Organism Streptococcus constellatus Streptococcus constellatus MIC = 0.008 ug/ml 19506065
NPT5315 Organism Streptococcus intermedius Streptococcus intermedius MIC = 0.008 ug/ml 19506065
NPT4066 Organism Streptococcus mitis Streptococcus mitis MIC = 0.008 ug/ml 19506065
NPT4401 Organism Streptococcus oralis Streptococcus oralis MIC = 0.008 ug/ml 19506065
NPT4403 Organism Streptococcus salivarius Streptococcus salivarius MIC = 0.008 ug/ml 19506065
NPT1172 Organism Streptococcus sanguinis Streptococcus sanguinis MIC = 0.008 ug/ml 19506065
NPT1228 Organism Streptococcus pyogenes Streptococcus pyogenes Activity = 0.06 % 19506065
NPT2 Others Unspecified Activity = 95.5 % 19506065
NPT2904 Organism Streptococcus equinus Streptococcus equinus Activity = 95.5 % 19506065
NPT5314 Organism Streptococcus constellatus Streptococcus constellatus Activity = 95.5 % 19506065
NPT5315 Organism Streptococcus intermedius Streptococcus intermedius Activity = 95.5 % 19506065
NPT4066 Organism Streptococcus mitis Streptococcus mitis Activity = 95.5 % 19506065
NPT4401 Organism Streptococcus oralis Streptococcus oralis Activity = 95.5 % 19506065
NPT4403 Organism Streptococcus salivarius Streptococcus salivarius Activity = 95.5 % 19506065
NPT1172 Organism Streptococcus sanguinis Streptococcus sanguinis Activity = 95.5 % 19506065
NPT1228 Organism Streptococcus pyogenes Streptococcus pyogenes MIC50 = 16 ug/ml 19506065
NPT2 Others Unspecified MIC50 = 16 ug/ml 19506065
NPT2904 Organism Streptococcus equinus Streptococcus equinus MIC50 = 0.06 ug/ml 19506065
NPT5314 Organism Streptococcus constellatus Streptococcus constellatus MIC50 = 0.06 ug/ml 19506065
NPT5315 Organism Streptococcus intermedius Streptococcus intermedius MIC50 = 0.06 ug/ml 19506065
NPT4066 Organism Streptococcus mitis Streptococcus mitis MIC50 = 0.06 ug/ml 19506065
NPT4401 Organism Streptococcus oralis Streptococcus oralis MIC50 = 0.06 ug/ml 19506065
NPT4403 Organism Streptococcus salivarius Streptococcus salivarius MIC50 = 0.06 ug/ml 19506065
NPT1172 Organism Streptococcus sanguinis Streptococcus sanguinis MIC50 = 0.06 ug/ml 19506065
NPT1228 Organism Streptococcus pyogenes Streptococcus pyogenes MIC90 = 16 ug/ml 19506065
NPT2 Others Unspecified MIC90 = 32 ug/ml 19506065
NPT2904 Organism Streptococcus equinus Streptococcus equinus MIC90 > 8 ug/ml 19506065
NPT5314 Organism Streptococcus constellatus Streptococcus constellatus MIC90 > 8 ug/ml 19506065
NPT5315 Organism Streptococcus intermedius Streptococcus intermedius MIC90 > 8 ug/ml 19506065
NPT4066 Organism Streptococcus mitis Streptococcus mitis MIC90 > 8 ug/ml 19506065
NPT4401 Organism Streptococcus oralis Streptococcus oralis MIC90 > 8 ug/ml 19506065
NPT4403 Organism Streptococcus salivarius Streptococcus salivarius MIC90 > 8 ug/ml 19506065
NPT1172 Organism Streptococcus sanguinis Streptococcus sanguinis MIC90 > 8 ug/ml 19506065
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 0.12 ug/ml 19506065
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC = 0.06 ug/ml 19506065
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC <= 0.03 ug/ml 19506065
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC <= 0.03 ug/ml 19506065
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC50 = 4 ug/ml 19506065
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC50 = 0.25 ug/ml 19506065
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC50 = 0.06 ug/ml 19506065
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC50 = 0.25 ug/ml 19506065
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC90 > 64 ug/ml 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.125 ug/ml 19770286
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 96 ug/ml 19770286
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 19770286
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.75 ug/ml 19770286
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 19770286
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 19770286
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1.5 ug/ml 19770286
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 24 ug/ml 19770286
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 19770286
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 3 ug/ml 19770286
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 19770286
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 32 ug/ml 19770287
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 >= 64 ug/ml 19770287
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC90 = 1 ug/ml 19506065
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC90 = 0.5 ug/ml 19506065
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC90 = 0.5 ug/ml 19506065
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Activity = 60.4 % 19506065
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus Activity = 92.6 % 19506065
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii Activity = 94 % 19506065
NPT2897 Organism Citrobacter freundii Citrobacter freundii Activity = 99 % 19506065
NPT5757 Organism Citrobacter koseri Citrobacter koseri MIC = 0.25 ug/ml 19506065
NPT5757 Organism Citrobacter koseri Citrobacter koseri MIC50 = 0.5 ug/ml 19506065
NPT5757 Organism Citrobacter koseri Citrobacter koseri MIC90 = 1 ug/ml 19506065
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC = 0.25 ug/ml 19506065
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.12 ug/ml 19506065
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes Activity = 100 % 19506065
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 100 % 19506065
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC50 = 0.5 ug/ml 19506065
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC50 = 0.25 ug/ml 19506065
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC90 = 8 ug/ml 19506065
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC90 = 1 ug/ml 19506065
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC = 1 ug/ml 19506065
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC50 = 2 ug/ml 19506065
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC50 = 4 ug/ml 19506065
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC90 = 8 ug/ml 19506065
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC = 0.25 ug/ml 19506065
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC50 = 0.5 ug/ml 19506065
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC90 = 1 ug/ml 19506065
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.12 ug/ml 19506065
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 100 % 19506065
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 0.25 ug/ml 19506065
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 1 ug/ml 19506065
NPT1465 Organism Legionella pneumophila Legionella pneumophila MIC = 0.03 ug/ml 19506065
NPT1121 Organism Moraxella catarrhalis Moraxella catarrhalis MIC = 0.015 ug/ml 19506065
NPT1121 Organism Moraxella catarrhalis Moraxella catarrhalis Activity = 100 % 19506065
NPT1465 Organism Legionella pneumophila Legionella pneumophila MIC50 = 0.12 ug/ml 19506065
NPT1121 Organism Moraxella catarrhalis Moraxella catarrhalis MIC50 = 0.03 ug/ml 19506065
NPT1465 Organism Legionella pneumophila Legionella pneumophila MIC90 = 1 ug/ml 19506065
NPT1121 Organism Moraxella catarrhalis Moraxella catarrhalis MIC90 = 0.03 ug/ml 19506065
NPT3495 Organism Morganella morganii Morganella morganii MIC = 0.25 ug/ml 19506065
NPT3495 Organism Morganella morganii Morganella morganii MIC50 = 1 ug/ml 19506065
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 10.8 % 19770287
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 8 % 19770287
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 76.5 % 19770287
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 92 % 19770287
NPT3495 Organism Morganella morganii Morganella morganii MIC90 = 4 ug/ml 19506065
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC = 0.25 ug/ml 19506065
NPT766 Organism Proteus vulgaris Proteus vulgaris MIC = 0.25 ug/ml 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.25 ug/ml 19506065
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 0.12 ug/ml 19506065
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC > 8 ug/ml 19506065
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC = 2 ug/ml 19506065
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC50 = 1 ug/ml 19506065
NPT766 Organism Proteus vulgaris Proteus vulgaris MIC50 = 1 ug/ml 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 2 ug/ml 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 8 ug/ml 19506065
NPT1248 Organism Serratia marcescens Serratia marcescens MIC50 = 0.5 ug/ml 19506065
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 > 8 ug/ml 19506065
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC90 = 4 ug/ml 19506065
NPT766 Organism Proteus vulgaris Proteus vulgaris MIC90 = 4 ug/ml 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 2 ug/ml 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 > 8 ug/ml 19506065
NPT1248 Organism Serratia marcescens Serratia marcescens MIC90 = 1 ug/ml 19506065
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 > 8 ug/ml 19506065
NPT172 Organism Proteus mirabilis Proteus mirabilis Activity = 100 % 19506065
NPT766 Organism Proteus vulgaris Proteus vulgaris Activity = 100 % 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 95.2 % 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 44.8 % 19506065
NPT1248 Organism Serratia marcescens Serratia marcescens Activity = 100 % 19506065
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity = 0 % 19506065
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity = 1.9 % 19506065
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.25 ug/ml 19528273
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 19528273
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 60 % 19528273
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 19687243
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 19687243
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 19687243
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 100 % 19721071
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 89 % 19721071
NPT19 Organism Escherichia coli Escherichia coli Activity = 100 % 19721071
NPT19 Organism Escherichia coli Escherichia coli Activity = 97 % 19721071
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 67 % 19721071
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 96 % 19721071
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 83 % 19721071
NPT3495 Organism Morganella morganii Morganella morganii Activity = 100 % 19721071
NPT172 Organism Proteus mirabilis Proteus mirabilis Activity = 0 % 19721071
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 19738007
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 19738007
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 256 ug/ml 19738007
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC = 25 ug/ml 19581465
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC < 0.25 ug/ml 18591275
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1.5 ug/ml 19188376
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1.5 ug/ml 19188376
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.25 ug/ml 19188376
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 19188376
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 19188376
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.19 ug/ml 19188376
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.38 ug/ml 19188376
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.25 ug/ml 19188376
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.38 ug/ml 19188376
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 19188376
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.75 ug/ml 19188376
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 2 ug/ml 20696867
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 1.5 ug/ml 20696867
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 32 ug/ml 18591275
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 0.5 ug/ml 18591275
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 1 ug/ml 18591275
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 2 ug/ml 18591275
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 18591275
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 16 ug/ml 18591275
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Activity = 61.2 % 18725452
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 8 ug/ml 18490506
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 8 ug/ml 18490506
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 8 ug/ml 18490506
NPT5774 Organism Citrobacter amalonaticus Citrobacter amalonaticus MIC > 8 ug/ml 18490506
NPT1248 Organism Serratia marcescens Serratia marcescens MIC > 8 ug/ml 18490506
NPT3495 Organism Morganella morganii Morganella morganii MIC = 4 ug/ml 18490506
NPT19 Organism Escherichia coli Escherichia coli MIC > 8 ug/ml 18490506
NPT3495 Organism Morganella morganii Morganella morganii MIC > 8 ug/ml 18490506
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC > 8 ug/ml 18490506
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC > 8 ug/ml 18490506
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 18490506
NPT5757 Organism Citrobacter koseri Citrobacter koseri MIC = 8 ug/ml 18490506
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC = 8 ug/ml 18490506
NPT1207 Organism Acinetobacter Acinetobacter MIC > 8 ug/ml 18490506
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 8 ug/ml 18490506
NPT2 Others Unspecified MIC > 8 ug/ml 18490506
NPT5774 Organism Citrobacter amalonaticus Citrobacter amalonaticus MIC = 8 ug/ml 18490506
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 8 ug/ml 18490506
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 8 ug/ml 18490506
NPT3495 Organism Morganella morganii Morganella morganii MIC = 8 ug/ml 18490506
NPT2 Others Unspecified MIC = 8 ug/ml 18490506
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC <= 1 ug/ml 20921306
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 8 ug/ml 20921306
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 2 ug/ml 20921306
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 4 ug/ml 20921306
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 16 ug/ml 20921306
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 20713658
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.25 ug/ml 21905738
NPT19 Organism Escherichia coli Escherichia coli MIC = 2.5 ug/ml 21905738
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 5 ug/ml 21905738
NPT2 Others Unspecified MIC > 40 ug/ml 21905738
NPT1264 Organism Burkholderia cepacia Burkholderia cepacia MIC > 40 ug/ml 21905738
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 21905738
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 21905738
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 21905738
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 21905738
NPT16 Organism Staphylococcus aureus Staphylococcus aureus FC = 5 21905738
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 21930375
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.25 ug/ml 21930375
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 21930375
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 21930375
NPT317 Uncleic Acid Nucleic Acid Kd > 100000 nM 22257890
NPT314 Organism Bacillus cereus Bacillus cereus IZ = 19 mm 10.1007/s00044-011-9911-y
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 18 mm 10.1007/s00044-011-9911-y
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 19 mm 10.1007/s00044-011-9911-y
NPT564 Organism Listeria monocytogenes Listeria monocytogenes IZ = 20 mm 10.1007/s00044-011-9911-y
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium IZ = 18 mm 10.1007/s00044-011-9911-y
NPT563 Organism Escherichia coli O157:H7 Escherichia coli O157:H7 IZ = 20 mm 10.1007/s00044-011-9911-y
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MBC = 24.1 ug/ml 10.1007/s00044-011-9933-5
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MBC = 28.1 ug/ml 10.1007/s00044-011-9933-5
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC = 26.5 ug/ml 10.1007/s00044-011-9933-5
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC = 13.7 ug/ml 10.1007/s00044-011-9933-5
NPT1863 Organism Staphylococcus saprophyticus Staphylococcus saprophyticus MBC = 25 ug/ml 10.1007/s00044-011-9933-5
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MBC = 50 ug/ml 10.1007/s00044-011-9933-5
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC = 11.8 ug/ml 10.1007/s00044-011-9933-5
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MBC = 17.3 ug/ml 10.1007/s00044-011-9933-5
NPT19 Organism Escherichia coli Escherichia coli MBC = 74 ug/ml 10.1007/s00044-011-9933-5
NPT19 Organism Escherichia coli Escherichia coli MBC = 64.3 ug/ml 10.1007/s00044-011-9933-5
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MBC = 78.1 ug/ml 10.1007/s00044-011-9933-5
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MBC = 83.3 ug/ml 10.1007/s00044-011-9933-5
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MBC = 68 ug/ml 10.1007/s00044-011-9933-5
NPT1228 Organism Streptococcus pyogenes Streptococcus pyogenes MIC = 7.81 ug/ml 10.1007/s00044-012-0419-x
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 15.62 ug/ml 10.1007/s00044-012-0419-x
NPT19 Organism Escherichia coli Escherichia coli IC50 = 15 nM 23786357
NPT2 Others Unspecified MIC = 64 ug/ml 23786357
NPT1277 Organism Staphylococcus epidermidis ATCC 12228 Staphylococcus epidermidis ATCC 12228 MIC = 0.3 ug/ml 23786357
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC = 18.8 ug/ml 23786357
NPT1550 Organism Bacillus anthracis Bacillus anthracis MIC = 9.4 ug/ml 23786357
NPT19 Organism Escherichia coli Escherichia coli MIC = 9.4 ug/ml 23786357
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 9.4 ug/ml 23786357
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 37.5 ug/ml 23786357
NPT2913 Organism Listeria monocytogenes ATCC 19115 Listeria monocytogenes ATCC 19115 MIC = 18.8 ug/ml 23786357
NPT314 Organism Bacillus cereus Bacillus cereus MIC = 75 ug/ml 23786357
NPT1107 Organism Mycobacterium smegmatis str. MC2 155 Mycobacterium smegmatis str. MC2 155 MIC = 0.6 ug/ml 23786357
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 9.4 ug/ml 23786357
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 2.3 ug/ml 23786357
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 24083676
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 24083676
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 24083676
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 24083676
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 24083676
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 24083676
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 24083676
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 1 ug/ml 24083676
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 0.5 ug/ml 24083676
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa GI = 100 % 24094434
NPT72 Individual Protein Solute carrier organic anion transporter family member 1B3 Homo sapiens Inhibition = 105.18 % 23571415
NPT73 Individual Protein Solute carrier organic anion transporter family member 1B1 Homo sapiens Inhibition = 197.1 % 23571415
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 24126094
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 16 ug/ml 24126094
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 24126094
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 24126094
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 24126094
NPT5579 Organism Aeromonas punctata Aeromonas caviae MIC = 32 ug/ml 24126094
NPT1843 Organism Aeromonas hydrophila Aeromonas hydrophila MIC = 16 ug/ml 24126094
NPT2 Others Unspecified MIC > 32 ug/ml 24126094
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 32 ug/ml 24126094
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 16 ug/ml 24126094
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 32 ug/ml 24126094
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 24126094
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC = 8 ug/ml 24126094
NPT2 Others Unspecified Potency 1012.4 nM PubChem BioAssay data set
NPT4778 Organism Streptococcus mutans UA159 Streptococcus mutans UA159 MIC = 128 ug/ml 10.1039/C2MD20162C
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 10.1039/C2MD20162C
NPT1204 Organism Enterococcus faecalis ATCC 29212 Enterococcus faecalis ATCC 29212 MIC > 128 ug/ml 10.1039/C2MD20162C
NPT1605 Organism Enterococcus Enterococcus MIC > 128 ug/ml 10.1039/C2MD20162C
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 128 ug/ml 10.1039/C2MD20162C
NPT1277 Organism Staphylococcus epidermidis ATCC 12228 Staphylococcus epidermidis ATCC 12228 MIC < 1 ug/ml 10.1039/C2MD20162C
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 128 ug/ml 10.1039/C2MD20162C
NPT2 Others Unspecified MIC = 64 ug/ml 10.1039/C2MD20162C
NPT1243 Organism Shigella sonnei Shigella sonnei MIC = 32 ug/ml 10.1039/C2MD20162C
NPT1243 Organism Shigella sonnei Shigella sonnei MIC = 16 ug/ml 10.1039/C2MD20162C
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 10.1039/C2MD20162C
NPT2 Others Unspecified Ki = 59900 nM 24709560
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 25050164
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 6400 nM 25936261
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 32 ug/ml 25981687
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 25981687
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 25981687
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.5 ug/ml 26590102
NPT19 Organism Escherichia coli Escherichia coli MIC = 3 ug/ml 26590102
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 3 ug/ml 26590102
NPT1246 Organism Salmonella Salmonella MIC = 3 ug/ml 26590102
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.5 ug/ml 26617967
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC <= 0.25 ug/ml 26617967
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 9.4 ug/ml 26617967
NPT564 Organism Listeria monocytogenes Listeria monocytogenes MIC = 2.3 ug/ml 26617967
NPT314 Organism Bacillus cereus Bacillus cereus MIC = 9.4 ug/ml 26617967
NPT2 Others Unspecified MIC > 128 ug/ml 26617967
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 128 ug/ml 26617967
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC = 4.7 ug/ml 26617967
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 0.6 ug/ml 26617967
NPT1107 Organism Mycobacterium smegmatis str. MC2 155 Mycobacterium smegmatis str. MC2 155 MIC >= 128 ug/ml 26617967
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.125 ug/ml 10.1039/C5MD00373C
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 10.1039/C5MD00373C
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 10.1039/C5MD00373C
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 10.1039/C5MD00373C
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 2 ug/ml 10.1039/C5MD00373C
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 10.1039/C5MD00373C
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 10.1039/C5MD00373C
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 10.1039/C5MD00373C
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 10.1039/C5MD00373C
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 8 ug/ml 10.1039/C5MD00377F
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 1 ug/ml 10.1039/C5MD00377F
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 8 ug/ml 10.1039/C5MD00377F

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC314408 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
1.0 High Similarity NPC314007
1.0 High Similarity NPC477060
1.0 High Similarity NPC123746
1.0 High Similarity NPC43850
0.9759 High Similarity NPC176381
0.9759 High Similarity NPC195969
0.9518 High Similarity NPC214376
0.9419 High Similarity NPC315334
0.9398 High Similarity NPC313552
0.9383 High Similarity NPC263058
0.9259 High Similarity NPC315969
0.9205 High Similarity NPC330590
0.8804 High Similarity NPC315036
0.878 High Similarity NPC318258
0.8602 High Similarity NPC56298
0.8602 High Similarity NPC471628
0.7778 Intermediate Similarity NPC221148
0.767 Intermediate Similarity NPC57436
0.767 Intermediate Similarity NPC121479
0.7609 Intermediate Similarity NPC470282
0.7586 Intermediate Similarity NPC316807
0.7531 Intermediate Similarity NPC291650
0.7531 Intermediate Similarity NPC322801
0.7531 Intermediate Similarity NPC129100
0.75 Intermediate Similarity NPC70574
0.75 Intermediate Similarity NPC306838
0.7453 Intermediate Similarity NPC241597
0.7386 Intermediate Similarity NPC98750
0.7333 Intermediate Similarity NPC271772
0.7333 Intermediate Similarity NPC36927
0.7113 Intermediate Similarity NPC328646
0.7111 Intermediate Similarity NPC83248
0.7111 Intermediate Similarity NPC100204
0.7065 Intermediate Similarity NPC165119
0.7033 Intermediate Similarity NPC471420
0.693 Remote Similarity NPC94319
0.6915 Remote Similarity NPC253975
0.6915 Remote Similarity NPC192025
0.6915 Remote Similarity NPC125253
0.6842 Remote Similarity NPC83839
0.6813 Remote Similarity NPC150557
0.6804 Remote Similarity NPC470284
0.6667 Remote Similarity NPC327753
0.6667 Remote Similarity NPC327486
0.6667 Remote Similarity NPC223174
0.6574 Remote Similarity NPC317534
0.6471 Remote Similarity NPC470283
0.6436 Remote Similarity NPC208537
0.6436 Remote Similarity NPC270005
0.6404 Remote Similarity NPC313813
0.6356 Remote Similarity NPC20035
0.6344 Remote Similarity NPC314772
0.6344 Remote Similarity NPC314968
0.6265 Remote Similarity NPC317023
0.6262 Remote Similarity NPC188453
0.6262 Remote Similarity NPC42320
0.6224 Remote Similarity NPC476523
0.6145 Remote Similarity NPC472025
0.6129 Remote Similarity NPC244539
0.6126 Remote Similarity NPC59589
0.6071 Remote Similarity NPC290179
0.6071 Remote Similarity NPC34877
0.6064 Remote Similarity NPC313762
0.6049 Remote Similarity NPC242073
0.6049 Remote Similarity NPC269166
0.6049 Remote Similarity NPC165198
0.6049 Remote Similarity NPC107914
0.6049 Remote Similarity NPC246558
0.6049 Remote Similarity NPC89145
0.6049 Remote Similarity NPC67660
0.6049 Remote Similarity NPC145112
0.6049 Remote Similarity NPC58629
0.6049 Remote Similarity NPC157514
0.6 Remote Similarity NPC314413
0.6 Remote Similarity NPC239705
0.6 Remote Similarity NPC314306
0.6 Remote Similarity NPC314398
0.5984 Remote Similarity NPC68327
0.5976 Remote Similarity NPC303727
0.5946 Remote Similarity NPC92874
0.5946 Remote Similarity NPC62845
0.5946 Remote Similarity NPC166242
0.5946 Remote Similarity NPC189854
0.5946 Remote Similarity NPC322449
0.593 Remote Similarity NPC477753
0.593 Remote Similarity NPC477755
0.593 Remote Similarity NPC477757
0.593 Remote Similarity NPC477762
0.593 Remote Similarity NPC477750
0.593 Remote Similarity NPC477763
0.5909 Remote Similarity NPC6848
0.5893 Remote Similarity NPC325900
0.5893 Remote Similarity NPC10897
0.587 Remote Similarity NPC476694
0.587 Remote Similarity NPC476695
0.587 Remote Similarity NPC476696
0.5862 Remote Similarity NPC17455
0.5843 Remote Similarity NPC315980
0.582 Remote Similarity NPC139857
0.581 Remote Similarity NPC61894
0.581 Remote Similarity NPC475603
0.5806 Remote Similarity NPC474468
0.5802 Remote Similarity NPC326533
0.5752 Remote Similarity NPC475918
0.5726 Remote Similarity NPC75839
0.5714 Remote Similarity NPC471418
0.5682 Remote Similarity NPC218150
0.5682 Remote Similarity NPC22774
0.5682 Remote Similarity NPC69669
0.5682 Remote Similarity NPC2432
0.5682 Remote Similarity NPC306462
0.5682 Remote Similarity NPC150680
0.5667 Remote Similarity NPC471760
0.5667 Remote Similarity NPC12040
0.5667 Remote Similarity NPC471761
0.5667 Remote Similarity NPC190418
0.5667 Remote Similarity NPC76881
0.5663 Remote Similarity NPC323361
0.5663 Remote Similarity NPC130683
0.5652 Remote Similarity NPC67099
0.5652 Remote Similarity NPC268922
0.5652 Remote Similarity NPC250619
0.5647 Remote Similarity NPC148424
0.5647 Remote Similarity NPC8979
0.5632 Remote Similarity NPC143326
0.561 Remote Similarity NPC233726
0.561 Remote Similarity NPC23134
0.561 Remote Similarity NPC124963
0.5604 Remote Similarity NPC477752
0.5604 Remote Similarity NPC477756
0.5604 Remote Similarity NPC477764
0.5604 Remote Similarity NPC477751

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC314408 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
1.0 High Similarity NPD3203 Approved
1.0 High Similarity NPD3209 Approved
1.0 High Similarity NPD3201 Approved
1.0 High Similarity NPD3208 Approved
1.0 High Similarity NPD3207 Approved
1.0 High Similarity NPD3202 Approved
0.9877 High Similarity NPD3200 Clinical (unspecified phase)
0.9759 High Similarity NPD5797 Approved
0.9759 High Similarity NPD5796 Clinical (unspecified phase)
0.9759 High Similarity NPD5798 Approved
0.9759 High Similarity NPD5794 Approved
0.9759 High Similarity NPD5795 Approved
0.9518 High Similarity NPD2698 Approved
0.9205 High Similarity NPD5381 Approved
0.9205 High Similarity NPD5377 Approved
0.9205 High Similarity NPD5378 Approved
0.8791 High Similarity NPD4282 Approved
0.8602 High Similarity NPD4836 Approved
0.8602 High Similarity NPD4837 Approved
0.8602 High Similarity NPD4838 Approved
0.8602 High Similarity NPD4835 Approved
0.8351 Intermediate Similarity NPD5376 Approved
0.7778 Intermediate Similarity NPD1449 Approved
0.7778 Intermediate Similarity NPD1450 Approved
0.767 Intermediate Similarity NPD4833 Approved
0.767 Intermediate Similarity NPD35 Approved
0.7531 Intermediate Similarity NPD9031 Approved
0.7531 Intermediate Similarity NPD9033 Approved
0.7531 Intermediate Similarity NPD9030 Approved
0.7531 Intermediate Similarity NPD9032 Approved
0.7453 Intermediate Similarity NPD3731 Phase 3
0.7429 Intermediate Similarity NPD2690 Discontinued
0.7353 Intermediate Similarity NPD2700 Approved
0.7347 Intermediate Similarity NPD6428 Approved
0.7315 Intermediate Similarity NPD4830 Approved
0.7315 Intermediate Similarity NPD4831 Approved
0.7315 Intermediate Similarity NPD4832 Approved
0.7209 Intermediate Similarity NPD67 Phase 2
0.7209 Intermediate Similarity NPD9034 Approved
0.708 Intermediate Similarity NPD6436 Phase 3
0.693 Remote Similarity NPD4828 Approved
0.693 Remote Similarity NPD4826 Approved
0.693 Remote Similarity NPD4827 Approved
0.6923 Remote Similarity NPD8045 Clinical (unspecified phase)
0.6757 Remote Similarity NPD3204 Clinical (unspecified phase)
0.6735 Remote Similarity NPD3716 Discontinued
0.6667 Remote Similarity NPD9445 Approved
0.6606 Remote Similarity NPD6941 Approved
0.6602 Remote Similarity NPD881 Approved
0.6355 Remote Similarity NPD7140 Approved
0.6355 Remote Similarity NPD7139 Approved
0.6355 Remote Similarity NPD7141 Clinical (unspecified phase)
0.6344 Remote Similarity NPD9435 Approved
0.6344 Remote Similarity NPD9434 Approved
0.625 Remote Similarity NPD8087 Discontinued
0.6214 Remote Similarity NPD1446 Phase 3
0.6214 Remote Similarity NPD1447 Phase 3
0.62 Remote Similarity NPD4759 Clinical (unspecified phase)
0.6118 Remote Similarity NPD6123 Approved
0.6075 Remote Similarity NPD2255 Approved
0.605 Remote Similarity NPD8345 Approved
0.605 Remote Similarity NPD8346 Approved
0.605 Remote Similarity NPD8347 Approved
0.6049 Remote Similarity NPD893 Approved
0.6049 Remote Similarity NPD892 Phase 3
0.6049 Remote Similarity NPD891 Phase 3
0.6049 Remote Similarity NPD890 Clinical (unspecified phase)
0.6049 Remote Similarity NPD888 Phase 3
0.6 Remote Similarity NPD6430 Approved
0.6 Remote Similarity NPD6429 Approved
0.5926 Remote Similarity NPD2269 Approved
0.5895 Remote Similarity NPD372 Clinical (unspecified phase)
0.5854 Remote Similarity NPD591 Approved
0.5854 Remote Similarity NPD577 Phase 3
0.5842 Remote Similarity NPD394 Phase 3
0.5841 Remote Similarity NPD8307 Discontinued
0.5802 Remote Similarity NPD905 Approved
0.5802 Remote Similarity NPD904 Phase 3
0.5789 Remote Similarity NPD8174 Phase 2
0.5745 Remote Similarity NPD389 Phase 3
0.5743 Remote Similarity NPD361 Discontinued
0.5702 Remote Similarity NPD8140 Approved
0.5682 Remote Similarity NPD9027 Phase 3
0.5682 Remote Similarity NPD9026 Phase 2
0.5682 Remote Similarity NPD9028 Phase 2
0.5682 Remote Similarity NPD9029 Phase 3
0.5663 Remote Similarity NPD894 Approved
0.5663 Remote Similarity NPD889 Approved
0.5663 Remote Similarity NPD887 Approved
0.5663 Remote Similarity NPD895 Approved

Structure

External Identifiers

PubChem CID   36294
ChEMBL   CHEMBL1747
ZINC  

Physicochemical Properties

Molecular Weight:  467.26
ALogP:  -7.5606
MLogP:  1.9
XLogP:  -5.381
# Rotatable Bonds:  16
Polar Surface Area:  268.17
# H-Bond Aceptor:  14
# H-Bond Donor:  10
# Rings:  3
# Heavy Atoms:  32

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Biological Activities  
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