Natural Product: NPC330590

Natural Product ID:  NPC330590
Common Name:   Amikacin
IUPAC Name:   (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
Synonyms:   Amikacin; Amikin
Molecular Formula:   C22H43N5O13
Standard InCHIKey:  LKCWBDHBTVXHDL-RMDFUYIESA-N
Standard InCHI:  InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1
Canonical SMILES:  NCC[C@@H](C(=N[C@@H]1C[C@H](N)[C@H]([C@@H]([C@H]1O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)N)O)O)O[C@H]1O[C@H](CN)[C@H]([C@@H]([C@H]1O)O)O)O)O
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO13391 Streptomyces hygroscopicus Species Streptomycetaceae Bacteria PMID[24224794]

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 17482816
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 20643902
NPT5768 Organism Acinetobacter pittii Acinetobacter pittii MIC50 = 32 ug/ml 23586757
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 26063305
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 500 nM 21256013
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 6 ug/ml PubChem BioAssay data set
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 19459694
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Activity = 6.62 10'8CFU/ml 19459694
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Activity = 27.81 /hr 18163584
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MBC = 8 ug/ml 18163584
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Activity = 0.55 /hr 19282186
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Ratio = 13 12350151
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 25 mm 20594858
NPT175 Organism Enterococcus faecalis Enterococcus faecalis IZ = 23 mm 20594858
NPT1228 Organism Streptococcus pyogenes Streptococcus pyogenes IZ = 20 mm 23200246
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 4 ug/ml 24844534
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 32 ug/ml 24844534
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC90 > 128 ug/ml 22472167
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC90 > 128 ug/ml 22472167
NPT19 Organism Escherichia coli Escherichia coli Activity = 1 % PubChem BioAssay data set
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.5 ug/ml 6988589
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 16 ug/ml 7658436
NPT19 Organism Escherichia coli Escherichia coli Activity = 100 % 9733489
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 4 ug/ml 9733489
NPT5738 Organism Enterobacter sp. Enterobacter sp. Activity = 95.2 % 6688829
NPT3497 Organism Klebsiella sp. Klebsiella sp. Activity = 13.3 % 10.1016/S0960-894X(00)80048-7
NPT3497 Organism Klebsiella sp. Klebsiella sp. Activity = 53.3 % 6688830
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae Activity = 8.3 % 6688830
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae Activity = 73.3 % 6688830
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC = 4 ug/ml 10780913
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 19101158
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 64 ug/ml 17958396
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC > 256 ug/ml 17958396
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 17958396
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 17958396
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 17958396
NPT317 Uncleic Acid Nucleic Acid Kd > 100000 nM 17958396
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 32 ug/ml 21441032
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 512 ug/ml PubChem BioAssay data set
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 30 ug/ml 23746784
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC = 30 ug/ml 23746784
NPT19 Organism Escherichia coli Escherichia coli MIC = 30 ug/ml 23746784
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 30 ug/ml 23746784
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 16 ug/ml 13678412
NPT5764 Organism Citrobacter Citrobacter MIC50 = 32 ug/ml 17287127
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 22608855
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 17850057
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 0.5 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 10.1016/j.cropro.2012.04.001
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC50 = 2 ug/ml 10.1016/j.cropro.2007.04.007
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC50 = 2 ug/ml PubChem BioAssay data set
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC50 = 1 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml PubChem BioAssay data set
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 256 ug/ml 12662097
NPT19 Organism Escherichia coli Escherichia coli MIC >= 128 ug/ml 22206869
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 22206869
NPT2 Others Unspecified MIC > 64 ug/ml 16274989
NPT2 Others Unspecified MIC > 64 ug/ml 21899267
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 26403929
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 26403929
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 11975490
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 15974612
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 10785421
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 10498214
NPT5772 Organism Enterobacter hormaechei Enterobacter hormaechei MIC = 8 ug/ml 20303767
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa FC >= 4 13678412
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 6 ug/ml 16309313
NPT3495 Organism Morganella morganii Morganella morganii MIC50 = 2 ug/ml 21955940
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 16933864
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC > 256 ug/ml 14695811
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 20677781
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 26151487
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 23977995
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 64 ug/ml 23977995
NPT1207 Organism Acinetobacter Acinetobacter MIC > 64 ug/ml 23977995
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 16933872
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC50 = 2 ug/ml 17958396
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 1 ug/ml 17958396
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 15787442
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 19734910
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml PubChem BioAssay data set
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 1 ug/ml PubChem BioAssay data set
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 128 ug/ml PubChem BioAssay data set
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml PubChem BioAssay data set
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 2 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 18327910
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 18327910
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 7264681
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.5 ug/ml 7264681
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 7264681
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 19586689
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 7760082
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 11277741
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 32 ug/ml 19006372
NPT3608 Organism Salmonella enteritidis Salmonella enterica subsp. enterica serovar Enteritidis MIC = 14000 nM 19199792
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 8 ug/ml 26110519
NPT3699 Organism Pseudomonas sp. Pseudomonas sp. MIC50 > 128 ug/ml 26287401
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 26287401
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 26287401
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 26287401
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC > 128 ug/ml 26287401
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 0.5 ug/ml 26287401
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 26287401
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml 26287401
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 22779787
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 22779787
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 10346943
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 8 ug/ml 8411013
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 8411013
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC <= 0.5 ug/ml 8411013
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 64 ug/ml 8411013
NPT6020 Organism Nocardia transvalensis Nocardia transvalensis MIC = 0.032 ug/ml 8411013
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 19097894
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 32 ug/ml 19097894
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 1 ug/ml 19097894
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 0.5 ug/ml 10757713
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 17 mm 19105653
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 8158155
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 6 ug/ml 23701597
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 22264170
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 22264170
NPT2895 Organism Providencia stuartii Providencia stuartii MIC = 1 ug/ml 22264170
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 22512738
NPT2894 Organism Providencia rettgeri Providencia rettgeri Activity = 80 % 22512738
NPT2897 Organism Citrobacter freundii Citrobacter freundii Activity = 31.6 % 21625478
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 1.7 % 11421749
NPT1264 Organism Burkholderia cepacia Burkholderia cepacia MIC50 = 128 ug/ml 20158243
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv EC50 = 70 nM 25935644
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 19 mm 10346946
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 > 64 ug/ml 26821820
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 4 ug/ml 26821820
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 18680278
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 18680278
NPT19 Organism Escherichia coli Escherichia coli MIC > 64 ug/ml 8230123
NPT19 Organism Escherichia coli Escherichia coli MIC < 2 ug/ml 8383730
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 8383730
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 8383730
NPT19 Organism Escherichia coli Escherichia coli MIC > 64 ug/ml 8383730
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 17378531
NPT2 Others Unspecified MIC = 96 ug/ml 11325246
NPT2 Others Unspecified MIC <= 6.00E-05 ug/ml 24547740
NPT2897 Organism Citrobacter freundii Citrobacter freundii Activity = 84 % 23327759
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes Activity = 83 % 23327759
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 92 % 20384296
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 17291748
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 48 % 12852746
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 1.9 % 24900468
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC = 4 ug/ml 12061875
NPT2 Others Unspecified Potency 105.9 nM 7562925
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC = 0.012 nM 10.1016/S0960-894X(97)00380-6
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 78.4 % 15267229
NPT2 Others Unspecified MIC = 0.5 ug/ml 16610794
NPT2 Others Unspecified MIC = 0.5 ug/ml 16750362
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 17158937
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 17049255
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1.5 ug/ml 17287123
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 17502416
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 2 ug/ml 17502416
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC > 32 ug/ml 17502416
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC <= 500 nM 19110434
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC > 1024 ug/ml 11975502
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 > 64 ug/ml 18547683
NPT2 Others Unspecified MIC = 0.25 ug/ml 20381216
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 32 ug/ml 20630628
NPT1246 Organism Salmonella Salmonella MIC90 = 8 ug/ml PubChem BioAssay data set
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 19223627
NPT5738 Organism Enterobacter sp. Enterobacter sp. Activity = 4.8 % 16472241
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.5 ug/ml 21342736
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MBC = 2 ug/ml PubChem BioAssay data set
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC90 = 8 ug/ml PubChem BioAssay data set
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC > 256 ug/ml DrugMatrix in vitro pharmacology data
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 2 ug/ml DrugMatrix in vitro pharmacology data
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 0.5 ug/ml 22194678
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC90 = 32 ug/ml 22182927
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC50 = 16 ug/ml 22182927
NPT1248 Organism Serratia marcescens Serratia marcescens MIC50 = 2 ug/ml 22264752
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 2 ug/ml 21906854
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa FC >= 4 10.1007/s00044-011-9676-3
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 10.1007/s00044-011-9676-3
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 10.1007/s00044-011-9642-0
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 10.1007/s00044-011-9642-0
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 10.1007/s00044-011-9661-x
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 10.1007/s00044-011-9661-x
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 32 ug/ml 10.1007/s00044-009-9178-8
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 11902656
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 32 ug/ml Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml Open TG-GATES in vivo data: Hematology
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml Open TG-GATES in vivo data: Hematology
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC90 = 4 ug/ml Open TG-GATES in vivo data: Hematology
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC50 = 1 ug/ml Open TG-GATES in vivo data: Hematology
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml Open TG-GATES in vivo data: Hematology
NPT3495 Organism Morganella morganii Morganella morganii MIC > 1 ug/ml Open TG-GATES in vivo data: Hematology
NPT1248 Organism Serratia marcescens Serratia marcescens MIC > 0.5 ug/ml Open TG-GATES in vivo data: Hematology
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae MIC50 = 2 ug/ml Open TG-GATES in vivo data: Hematology
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae MIC90 > 64 ug/ml Open TG-GATES in vivo data: Hematology
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae MIC50 = 4 ug/ml Open TG-GATES in vivo data: Hematology
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae MIC90 = 8 ug/ml Open TG-GATES in vivo data: Hematology
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae MIC50 = 8 ug/ml Open TG-GATES in vivo data: Hematology
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 128 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT1118 Organism Streptococcus pneumoniae Streptococcus pneumoniae MIC = 0.5 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT2 Others Unspecified MIC50 = 8 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv Inhibition = 96 % Open TG-GATES in vivo data: Biochemistry
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv Inhibition = 79.8 % Open TG-GATES in vivo data: Biochemistry
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv Inhibition = 98 % Open TG-GATES in vivo data: Biochemistry
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 3 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT3699 Organism Pseudomonas sp. Pseudomonas sp. MIC50 = 4 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 4 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT2 Others Unspecified MIC90 = 1 ug/ml DrugMatrix in vivo data: Pathology
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml DrugMatrix in vivo data: Pathology
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.13 ug/ml DrugMatrix in vivo data: Hematology
NPT2 Others Unspecified MIC = 12000 nM 26296475
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 26331426
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 26331426
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 128 ug/ml 26331426
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 26331426
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC > 128 ug/ml 26331426
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 26331426
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 26331426
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 23691952
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 32 ug/ml 22705001
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 11374949
NPT2 Others Unspecified MIC <= 6.00E-05 ug/ml 23190013
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC > 64 ug/ml 8277308
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 8277308
NPT314 Organism Bacillus cereus Bacillus cereus MIC = 9.4 ug/ml 8277308
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC < 2 ug/ml 8277308
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 10924160
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 10924160
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 17958396
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 63.2 % 17958396
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes Activity = 55 % 17958396
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 0.5 ug/ml 22168134
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 15043404
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 18298075
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 7623047
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 7623047
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 7623047
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 7623047
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 7623047
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 4 ug/ml 7623047
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 64 ug/ml 23305465
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 256 ug/ml 16252909
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 32 ug/ml 21106454
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 8482949
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 18951805
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 18951805
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 18951805
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 8 ug/ml 10.1016/S0960-894X(01)80580-1
NPT5769 Organism Nocardia brasiliensis Nocardia brasiliensis MIC = 0.001 ug/ml 9134742
NPT2 Others Unspecified MIC = 0.0005 ug/ml 10425119
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae IZ = 25 mm 9461657
NPT79 Organism Bacillus subtilis Bacillus subtilis IZ = 32 mm 9461657
NPT729 Organism Micrococcus luteus Micrococcus luteus IZ = 31 mm 9461657
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 30 mm 9461657
NPT19 Organism Escherichia coli Escherichia coli IZ = 30 mm 9461657
NPT483 Individual Protein Prelamin-A/C Homo sapiens Potency = 158.5 nM 12141872
NPT19 Organism Escherichia coli Escherichia coli MIC > 64 ug/ml 20337486
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC = 8 ug/ml 24224794
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 24224794
NPT5768 Organism Acinetobacter pittii Acinetobacter pittii MIC90 >= 64 ug/ml PubChem BioAssay data set
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 32 ug/ml 1707976
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 3351854
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Ratio = 20 10757717
NPT1207 Organism Acinetobacter Acinetobacter MIC = 8 ug/ml 2778449
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 20188576
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 24 ug/ml DrugMatrix in vitro pharmacology data
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC90 = 8 ug/ml DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml DrugMatrix in vitro pharmacology data
NPT19 Organism Escherichia coli Escherichia coli MIC = 128 ug/ml 12488537
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC90 = 160 nM DrugMatrix in vivo data: Biochemistry
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 1.71 umol/ml DrugMatrix in vivo data: Hematology
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 27.32 umol/ml DrugMatrix in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 1.71 umol/ml DrugMatrix in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml DrugMatrix in vivo data: Hematology
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 8 ug/ml DrugMatrix in vivo data: Hematology
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 96.4 % DrugMatrix in vivo data: Hematology
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 100 % 15646539
NPT3497 Organism Klebsiella sp. Klebsiella sp. MIC50 = 16 ug/ml 226705
NPT3497 Organism Klebsiella sp. Klebsiella sp. MIC90 > 32 ug/ml 226705
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 16 ug/ml PubChem BioAssay data set
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 15568791
NPT19 Organism Escherichia coli Escherichia coli Activity = 35 % 20038159
NPT19 Organism Escherichia coli Escherichia coli Activity = 45 % 17988099
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis IZ = 22 mm 23022281
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 16 ug/ml 7714533
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 19534474
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 17190458
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 17190458
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 17190458
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 17190458
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC > 256 ug/ml 19482481
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC = 32 ug/ml 20739103
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 18426895
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 8 ug/ml 18426895
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 32 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC50 = 16 ug/ml DrugMatrix in vitro pharmacology data
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 512 ug/ml DrugMatrix in vitro pharmacology data
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC >= 250 ug/ml DrugMatrix in vitro pharmacology data
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml DrugMatrix in vitro pharmacology data
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 = 4 ug/ml 22194678
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 = 16 ug/ml 22172700
NPT2 Others Unspecified MIC90 > 128 ug/ml 22172700
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 12 ug/ml PubChem BioAssay data set
NPT4080 Organism Acinetobacter sp. Acinetobacter sp. MIC50 > 64 ug/ml PubChem BioAssay data set
NPT4080 Organism Acinetobacter sp. Acinetobacter sp. MIC90 > 64 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 25082514
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 25082514
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 16 ug/ml 21282406
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 50 % 21123165
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.9 ug/ml DailyMed
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 90.9 % DailyMed
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml DailyMed
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 2 ug/ml DailyMed
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 10096871
NPT19 Organism Escherichia coli Escherichia coli Activity = 81 % PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 25760525
NPT2911 Organism Pseudomonas putida Pseudomonas putida MIC = 1 ug/ml 24328302
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 19067555
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 19836230
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC50 = 16 ug/ml 18355033
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 8 ug/ml 15270567
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 48 ug/ml PubChem BioAssay data set
NPT5768 Organism Acinetobacter pittii Acinetobacter pittii MIC = 0.5 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 10.6019/CHEMBL1201861
NPT445 Individual Protein Peripheral myelin protein 22 Rattus norvegicus Potency 9074.3 nM 10.6019/CHEMBL1201861
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 10.6019/CHEMBL1201861
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 10.6019/CHEMBL1201861
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 10.6019/CHEMBL1201861
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 2 ug/ml 10.6019/CHEMBL1201861
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 20 mm 10.6019/CHEMBL1201861
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 17 mm 10.6019/CHEMBL1201861
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 10.6019/CHEMBL1201861
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 10.6019/CHEMBL1201861
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv IC90 = 141 nM 25798528
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.9 ug/ml 25316316
NPT564 Organism Listeria monocytogenes Listeria monocytogenes MIC = 9.4 ug/ml 25316316
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa FC >= 4 22276679
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa FC >= 4 24428261
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 16562839
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 16562839
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 22019045
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 23964704
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 10217729
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 10217729
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 17428093
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 17428093
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 64 ug/ml 10650083
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4 ug/ml 10650083
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 32 ug/ml 10425121
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 32 ug/ml 24484201
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 0.5 ug/ml 8254346
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC > 128 ug/ml 17502402
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC90 > 128 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml PubChem BioAssay data set
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml PubChem BioAssay data set
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4 ug/ml 23819871
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 22691179
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 28.6 % 12502332
NPT19 Organism Escherichia coli Escherichia coli Activity = 12.5 % 11520222
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 9392880
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 256 ug/ml 9392880
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 2 ug/ml 9392880
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 64 ug/ml 19775092
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 32 ug/ml 19775092
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 19775092
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 256 ug/ml 19775092
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 128 ug/ml 19746919
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 19746919
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.9 ug/ml 12608859
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 8 ug/ml 23876004
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 24359303
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 8277314
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 18053715
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 22440015
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 12 ug/ml 10924160
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC50 = 4 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 64 ug/ml 16933872
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 16933872
NPT2 Others Unspecified MIC = 0.00025 ug/ml 16933872
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 7506311
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 16562846
NPT19 Organism Escherichia coli Escherichia coli MIC <= 0.5 ug/ml 10757713
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 4 ug/ml 8759172
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 24484240
NPT19 Organism Escherichia coli Escherichia coli Activity = 35 % 24484240
NPT19 Organism Escherichia coli Escherichia coli Activity = 5 % 24484240
NPT19 Organism Escherichia coli Escherichia coli Activity = 11 % 24484240
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 25052206
NPT19 Organism Escherichia coli Escherichia coli Activity = 8 % 25052206
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 102 % 3210015
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 10924160
NPT1248 Organism Serratia marcescens Serratia marcescens Activity = 30 % PubChem BioAssay data set
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 23301853
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 3 ug/ml 20951582
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 20951582
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 93.3 % PubChem BioAssay data set
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 16 ug/ml 8254346
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 14 ug/ml 18610999
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 32 ug/ml 8350092
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 > 64 ug/ml 8350092
NPT19 Organism Escherichia coli Escherichia coli MIC < 2 ug/ml 23562058
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 23562058
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC < 1 ug/ml 24836069
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 24836069
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 25176187
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC90 = 64 ug/ml 19916528
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca Activity = 86 % 21044847
NPT19 Organism Escherichia coli Escherichia coli Activity = 98 % 21044847
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 73 % 21044847
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca Activity = 100 % 21044847
NPT172 Organism Proteus mirabilis Proteus mirabilis Activity = 92 % 21044847
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 99 % 21044847
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 85 % 12444692
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC50 > 128 ug/ml 26091285
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 32000 nM 26091285
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 32000 nM 26091285
NPT19 Organism Escherichia coli Escherichia coli MIC > 512 ug/ml 26222693
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC <= 2 ug/ml 24673739
NPT3699 Organism Pseudomonas sp. Pseudomonas sp. MIC90 = 16 ug/ml 26951751
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 16 ug/ml 26951751
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 25 ug/ml 26331426
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 25 ug/ml 12662097
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.6 ug/ml 12662097
NPT2 Others Unspecified MIC = 11950 nM 15730242
NPT19 Organism Escherichia coli Escherichia coli IZ = 20 mm 22652254
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 3 ug/ml 15270564
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 12 ug/ml 15270564
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 8 ug/ml 15270564
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 128 ug/ml 15270564
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 15270564
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 24709561
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 24709561
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 23145909
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 1 ug/ml 25924111
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 1 ug/ml 25924111
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 32 ug/ml 15568794
NPT2 Others Unspecified MIC90 > 64 ug/ml 24164206
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 99 % 18942825
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 80.6 % 8021914
NPT5311 Organism Mycobacterium mageritense Mycobacterium mageritense MIC = 0.5 ug/ml 23062825
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 > 64 ug/ml 24900361
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 32 ug/ml 12502320
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 4 ug/ml 15217270
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC = 4 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified MIC90 = 8 ug/ml PubChem BioAssay data set
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 19785430
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml 20061160
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC > 256 ug/ml 20022253
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 0.9 ug/ml 20022253
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC50 = 8 ug/ml 18800848
NPT2895 Organism Providencia stuartii Providencia stuartii MIC50 = 2 ug/ml 15921415
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 2 ug/ml 23270663
NPT1824 Organism Clostridium sporogenes Clostridium sporogenes MIC = 25610 nM 11374942
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 24 ug/ml 8254346
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 22472691
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 406395
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 15620246
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 32 ug/ml 15620246
NPT19 Organism Escherichia coli Escherichia coli MIC = 128 ug/ml 15620246
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 32 ug/ml 15620246
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 128 ug/ml 15620246
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 64 ug/ml 16792413
NPT1248 Organism Serratia marcescens Serratia marcescens MIC > 128 ug/ml 16792413
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 25734332
NPT19 Organism Escherichia coli Escherichia coli MIC <= 2 ug/ml 17253840
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 32 ug/ml 17253840
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 256 ug/ml 21667925
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml PubChem BioAssay data set
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC50 = 8 ug/ml 12502331
NPT3189 Organism Haemophilus parainfluenzae Haemophilus parainfluenzae MIC50 = 4 ug/ml 12502331
NPT3495 Organism Morganella morganii Morganella morganii MIC50 = 1 ug/ml 24582402
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 71720 nM 20558060
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 20025236
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 512 ug/ml 17336532
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 64 ug/ml 18321057
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC > 512 ug/ml 10096857
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 18507472
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 12662097
NPT1118 Organism Streptococcus pneumoniae Streptococcus pneumoniae MIC = 8 ug/ml 12662097
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 2 ug/ml 12662097
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 1 ug/ml 12662097
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 12662097
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 32 ug/ml 24168147
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 64 ug/ml 22552195
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC50 = 2 ug/ml PubChem BioAssay data set
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC50 = 0.5 ug/ml 23190013
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 22934537
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 22934537
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC = 1 ug/ml 25479041
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MBC = 128 ug/ml 25479041
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC90 = 16 ug/ml 17288478
NPT2 Others Unspecified Potency 23710.1 nM 21377877
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli Activity = 97 % PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 10843574
NPT19 Organism Escherichia coli Escherichia coli Activity = 78.9 % 10843574
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 78.9 % 21420867
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 18829331
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 21177985
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 > 128 ug/ml PubChem BioAssay data set
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 > 128 ug/ml 23571415
NPT1264 Organism Burkholderia cepacia Burkholderia cepacia MIC90 > 128 ug/ml PubChem BioAssay data set
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae IZ = 11 mm 27096049
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 20 mm 27096049
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis IZ = 25 mm 27096049
NPT314 Organism Bacillus cereus Bacillus cereus IZ = 20 mm 17067147
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 15 mm 25600409
NPT79 Organism Bacillus subtilis Bacillus subtilis IZ = 21 mm 2607352
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 17850214
NPT6018 Organism Nocardia otitidiscaviarum Nocardia otitidiscaviarum MIC = 0.001 ug/ml 10.6019/CHEMBL1201861
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 10.6019/CHEMBL1201861
NPT1107 Organism Mycobacterium smegmatis str. MC2 155 Mycobacterium smegmatis str. MC2 155 MIC <= 0.25 ug/ml 10.6019/CHEMBL1201861
NPT189 Cell Line Vero Chlorocebus aethiops IC50 > 62.5 ug/ml 10.6019/CHEMBL1201861
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 22260257
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa FC >= 4 24582402
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 24582402
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa FC >= 4 11575965
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv IC90 = 80 nM 17696332
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 17696332
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC90 = 16 ug/ml 18672864
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 21737271
NPT19 Organism Escherichia coli Escherichia coli Activity = 93 % 21737271
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 82.1 % 21719287
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 160 nM 22769561
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 5 ug/ml 18447384
NPT4080 Organism Acinetobacter sp. Acinetobacter sp. MIC = 32 ug/ml 19572613
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 15332848
NPT5775 Organism Serratia sp. Serratia sp. MIC50 = 8 ug/ml 19743809
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 19743809
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml Patent: US8470888 B2
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 22209731
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC = 2 ug/ml 19928832
NPT4584 Organism Nocardia sp. Nocardia sp. MIC = 0.00025 ug/ml 20624681
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 16 ug/ml 23290051
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 0 % 18278869
NPT5768 Organism Acinetobacter pittii Acinetobacter pittii Activity = 52.6 % 7528786
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 22545792
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 8 ug/ml 17315955
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 8350094
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 23394318
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 1 ug/ml 10.1016/S0960-894X(01)80927-6
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 2000 nM 3039137
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC90 = 8 ug/ml 16040241
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 2 ug/ml 17060530
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 17257839
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC90 = 64 ug/ml 17587585
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 64 ug/ml 17420206
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 64 ug/ml 17420206
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC50 = 16 ug/ml 17420206
NPT19 Organism Escherichia coli Escherichia coli Activity = 32 % 18681480
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 18681480
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 18417256
NPT19 Organism Escherichia coli Escherichia coli Activity = 6 % 18417256
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 18417256
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 12141853
NPT19 Organism Escherichia coli Escherichia coli Activity = 39 % 17606689
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 11975502
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 18973387
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 32 ug/ml 18443115
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.25 ug/ml 18955526
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 > 64 ug/ml 18644957
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 16 ug/ml 18644957
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 18955529
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 18838581
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 18838581
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1.5 ug/ml 18838581
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 6 ug/ml 18838581
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 48 ug/ml 18838581
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 16 ug/ml 18838581
NPT5738 Organism Enterobacter sp. Enterobacter sp. MIC50 = 8 ug/ml 20801553
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC50 = 2 ug/ml 18955526
NPT1513 Organism Mycobacterium avium Mycobacterium avium MIC = 1.56 ug/ml 18955526
NPT1513 Organism Mycobacterium avium Mycobacterium avium MIC > 100 ug/ml 18955526
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 1.75 ug/ml 18955526
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 18443128
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC > 0.5 ug/ml 18443128
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 18443129
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.9 ug/ml 18458127
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 18541727
NPT1190 Organism Salmonella enterica Salmonella enterica MIC = 13660 nM 21035332
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 32 ug/ml 19029325
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 19064900
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 16 ug/ml 19124662
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 = 128 ug/ml 19124664
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 19029333
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 19029333
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 19223615
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 19506058
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 19651906
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 19651906
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml 19651906
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 19651906
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 19651906
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 19770275
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 19770275
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 19651910
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC <= 500 nM 21130541
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 19581457
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 24 ug/ml 18625769
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 6 ug/ml 18625769
NPT3699 Organism Pseudomonas sp. Pseudomonas sp. Activity = 7.7 % 19581457
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC = 37.5 ug/ml 19581457
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 > 256 ug/ml 19581457
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 1 ug/ml 18625769
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 > 256 ug/ml 19581457
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 19581457
NPT19 Organism Escherichia coli Escherichia coli MIC = 9000 nM 20547799
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 21078949
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 20696876
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae IZ = 21 mm DrugMatrix in vitro pharmacology data
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 2 ug/ml DrugMatrix in vitro pharmacology data
NPT2894 Organism Providencia rettgeri Providencia rettgeri Activity = 84.6 % DrugMatrix in vitro pharmacology data
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus Activity = 98 % DrugMatrix in vitro pharmacology data
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 22440624
NPT2 Others Unspecified MIC <= 6.00E-05 ug/ml 22652254
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 10.1007/s00044-011-9827-6
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 32 ug/ml 10.1007/s00044-009-9288-3
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Activity = 28.6 % 10.1007/s00044-010-9440-0
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 96 ug/ml 10.1007/s00044-009-9206-8
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC <= 0.03 ug/ml 10.1007/s00044-011-9964-y
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.25 ug/ml 10.1007/s00044-011-9964-y
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 8 ug/ml 10.1007/s00044-013-0567-7
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 10.1007/s00044-012-0320-7
NPT5738 Organism Enterobacter sp. Enterobacter sp. MIC90 = 64 ug/ml 23567957
NPT79 Organism Bacillus subtilis Bacillus subtilis Kd = 760000 nM 10.1007/s00044-013-0844-5
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC = 0.5 ug/ml 24095755
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC > 0.5 ug/ml DrugMatrix in vivo data: Pathology
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 24486419
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 24513045
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 24694215
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 64 ug/ml 23344796
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv EC50 = 120 nM 10.1039/C4MD00399C
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 26510047
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 26564265
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 8 ug/ml 26564265
NPT172 Organism Proteus mirabilis Proteus mirabilis Activity = 100 % 26765953
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 26900659
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 27216998
NPT19 Organism Escherichia coli Escherichia coli IZ = 22 mm PubChem BioAssay data set
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.5 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 19928832
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC90 = 125 ug/ml 19928832
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 10843594
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 18811205
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC = 64 ug/ml 12398531
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC = 0.9 ug/ml PubChem BioAssay data set
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 17315963
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 11720539
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 22873794
NPT5774 Organism Citrobacter amalonaticus Citrobacter amalonaticus MIC > 128 ug/ml 26035018
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC > 128 ug/ml 26035018
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 26035018
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 25681711
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC = 1.25 ug/ml 22381047
NPT2 Others Unspecified MIC > 32 ug/ml 22381047
NPT2 Others Unspecified MIC > 32 ug/ml 16252924
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 16252924
NPT2 Others Unspecified MIC = 0.78 ug/ml 11141097
NPT1248 Organism Serratia marcescens Serratia marcescens MIC50 = 1 ug/ml 9014350
NPT2 Others Unspecified Ratio = 0.125 24035341
NPT2 Others Unspecified Ratio = 2 16499317
NPT2 Others Unspecified Ratio = 1 16499317
NPT2 Others Unspecified Ratio = 2 19860383
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 19860383
NPT2 Others Unspecified Ratio = 0.5 21493075
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 23327668
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Activity = 36.7 % 23327794
NPT5738 Organism Enterobacter sp. Enterobacter sp. MIC90 = 16 ug/ml 16499319
NPT1248 Organism Serratia marcescens Serratia marcescens MIC90 = 2 ug/ml 10579870
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa FC >= 4 18163584
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 3 ug/ml PubChem BioAssay data set
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae MIC90 = 32 ug/ml PubChem BioAssay data set
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae MIC50 = 8 ug/ml PubChem BioAssay data set
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 17352491
NPT19 Organism Escherichia coli Escherichia coli MIC50 <= 8 ug/ml 16417306
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 16417306
NPT62 Individual Protein 6-phospho-1-fructokinase Trypanosoma brucei Potency 39810.7 nM 22280816
NPT4080 Organism Acinetobacter sp. Acinetobacter sp. MIC90 > 64 ug/ml 25647077
NPT4080 Organism Acinetobacter sp. Acinetobacter sp. MIC50 = 4 ug/ml 25647077
NPT3189 Organism Haemophilus parainfluenzae Haemophilus parainfluenzae MIC = 2 ug/ml 18597527
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC = 4 ug/ml 18597527
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 19318257
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 4 ug/ml 19318257
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC = 4 ug/ml 19318257
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 21235220
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 8000 nM PubChem BioAssay data set
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC90 = 32 ug/ml 10924160
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC90 = 2 ug/ml 10924160
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 51 % 20627740
NPT19 Organism Escherichia coli Escherichia coli IZ = 16.2 mm 9358643
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 21802177
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 23 mm PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC < 2 ug/ml 10.1584/jpestics.24.149
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 16643031
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 23543830
NPT3599 Organism Staphylococcus capitis Staphylococcus capitis MIC = 0.5 ug/ml 26551342
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 0.8 ug/ml 26551342
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 26551342
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 26551342
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 25286284
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv EC50 = 70 nM 25286284
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC50 = 16 ug/ml 16562846
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC50 = 16 ug/ml 22148475
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 8176404
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 10479316
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 256 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 20430633
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 16 ug/ml 23200246
NPT2 Others Unspecified MIC <= 0.5 ug/ml 19921834
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 64 ug/ml 14640511
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 8 ug/ml 17190457
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 15497961
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 8496706
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 11809075
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 8496706
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 8496706
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 4 ug/ml PubChem BioAssay data set
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC90 = 8 ug/ml PubChem BioAssay data set
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 1 ug/ml 16643022
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 2 ug/ml 20813948
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 2 ug/ml PubChem BioAssay data set
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 10.6019/CHEMBL1201861
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 10.6019/CHEMBL1201861
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 16 ug/ml 10.6019/CHEMBL1201861
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 16 ug/ml 10.6019/CHEMBL1201861
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 4 ug/ml 10.6019/CHEMBL1201861
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 10.6019/CHEMBL1201861
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 10.6019/CHEMBL1201861
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 64 ug/ml 10.6019/CHEMBL1201861
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 32 ug/ml 10.6019/CHEMBL1201861
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 4 ug/ml 10.6019/CHEMBL1201861
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 10.6019/CHEMBL1201861
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC <= 2 ug/ml 10.6019/CHEMBL1201861
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 16 ug/ml 10.6019/CHEMBL1201861
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT766 Organism Proteus vulgaris Proteus vulgaris MIC = 512 ug/ml 10.6019/CHEMBL1201861
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 1 ug/ml 10.6019/CHEMBL1201861
NPT2 Others Unspecified IC50 = 1020 nM 10.6019/CHEMBL1201861
NPT2 Others Unspecified Inhibition = 43 % 10.6019/CHEMBL1201861
NPT2 Others Unspecified IC50 = 160 nM 10.6019/CHEMBL1201861
NPT2 Others Unspecified Inhibition = 85 % 10.6019/CHEMBL1201861
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC50 = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 1 ug/ml 10.6019/CHEMBL1201861
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 0 % 19017562
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 0 % 19447629
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 0 % 9644053
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 2.4 % 9644053
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 0 % 18039011
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC90 = 160 nM 9514009
NPT3495 Organism Morganella morganii Morganella morganii MIC50 = 1 ug/ml 26034885
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC50 = 2 ug/ml 26034885
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 2 ug/ml 22901896
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MBC = 64 ug/ml 22901896
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MBC = 32 ug/ml 22901896
NPT2 Others Unspecified MIC = 0.25 ug/ml 7623047
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 14640511
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 1982768
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 106 % 17844994
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 = 128 ug/ml 20038128
NPT3699 Organism Pseudomonas sp. Pseudomonas sp. MIC90 > 128 ug/ml 20038128
NPT443 Individual Protein Histone acetyltransferase GCN5 Homo sapiens Potency 31622.8 nM 8289059
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC50 = 16 ug/ml PubChem BioAssay data set
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC = 0.001 ug/ml 25856683
NPT19 Organism Escherichia coli Escherichia coli MIC = 48 ug/ml 25856683
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC < 1 ug/ml 25856683
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 25237727
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 24697496
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis Activity = 73.1 % 17988094
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC >= 64 ug/ml 19839605
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC >= 64 ug/ml 19515569
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC >= 64 ug/ml PubChem BioAssay data set
NPT1824 Organism Clostridium sporogenes Clostridium sporogenes MIC = 26000 nM 26547057
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 11356111
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 11356111
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 500 nM 10395485
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 1662724
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 8691468
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC > 256 ug/ml 8182704
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 2 ug/ml 9871772
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.5 ug/ml 8389875
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 8389875
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 2821258
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 2821258
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 2821258
NPT2895 Organism Providencia stuartii Providencia stuartii MIC = 16 ug/ml 2821258
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 2 ug/ml 2821258
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 1 ug/ml 2821258
NPT19 Organism Escherichia coli Escherichia coli MIC = 256 ug/ml 2821258
NPT3495 Organism Morganella morganii Morganella morganii Activity = 83.3 % 14592517
NPT3888 Organism Micrococcus flavus Micrococcus flavus MIC = 3420 nM 15658872
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 18558490
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 18558490
NPT5299 Organism Staphylococcus sp. Staphylococcus sp. MIC90 > 64 ug/ml 20071056
NPT5299 Organism Staphylococcus sp. Staphylococcus sp. MIC50 = 16 ug/ml 20071056
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 20356735
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1 ug/ml 21489802
NPT19 Organism Escherichia coli Escherichia coli MIC = 1.5 ug/ml 21419530
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 21435753
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 48 ug/ml 21477899
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.75 ug/ml 21477899
NPT1827 Organism Mycobacterium bovis Mycobacterium bovis MIC = 0.125 ug/ml DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml DrugMatrix in vitro pharmacology data
NPT1248 Organism Serratia marcescens Serratia marcescens MIC90 > 128 ug/ml 22032697
NPT3495 Organism Morganella morganii Morganella morganii MIC90 = 4 ug/ml 22041063
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 22104973
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 22244588
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC > 0.5 ug/ml 23305918
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC = 0.5 ug/ml 23182091
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC <= 500 nM 10.6019/CHEMBL1201861
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 16 ug/ml 10.6019/CHEMBL1201861
NPT317 Uncleic Acid Nucleic Acid Kd = 50 nM 10.6019/CHEMBL1201861
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.9 ug/ml 10.6019/CHEMBL1201861
NPT2 Others Unspecified MIC = 1 ug/ml 10.6019/CHEMBL1201861
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv IC50 = 70 nM 10.6019/CHEMBL1201861
NPT2895 Organism Providencia stuartii Providencia stuartii MIC90 = 8 ug/ml 10.6019/CHEMBL1201861
NPT2 Others Unspecified Inhibition = 0 % 10.6019/CHEMBL1201861
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv IC50 = 0.07 ug/ml 23999041
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC50 = 1 ug/ml 10.1007/s00044-013-0757-3
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC = 1 ug/ml Open TG-GATES in vivo data: Hematology
NPT3495 Organism Morganella morganii Morganella morganii MIC = 1 ug/ml Open TG-GATES in vivo data: Hematology
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1 ug/ml Open TG-GATES in vivo data: Hematology
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC90 = 32 ug/ml Open TG-GATES in vivo data: Hematology
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 > 128 ug/ml Open TG-GATES in vivo data: Hematology
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MBC = 2 ug/ml Open TG-GATES in vivo data: Hematology
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC50 = 16 ug/ml Open TG-GATES in vivo data: Hematology
NPT5738 Organism Enterobacter sp. Enterobacter sp. MIC50 = 2 ug/ml Open TG-GATES in vivo data: Hematology
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 16 ug/ml Open TG-GATES in vivo data: Hematology
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Ratio = 1 Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli Activity = 46 % Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli Activity = 69 % Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli Activity = 48 % Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli Activity = 37 % Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli Activity = 3 % Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli Activity = 44 % Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli Activity = 31 % Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli Activity = 34 % Open TG-GATES in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli Activity = 36 % Open TG-GATES in vivo data: Hematology
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC90 = 4 ug/ml Open TG-GATES in vivo data: Hematology
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae MIC50 > 256 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 256 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 16 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Activity = 71.4 % Open TG-GATES in vivo data: Biochemistry
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml Open TG-GATES in vivo data: Organ Weight
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC > 128 ug/ml DrugMatrix in vivo data: Pathology
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 0.5 ug/ml DrugMatrix in vivo data: Biochemistry
NPT19 Organism Escherichia coli Escherichia coli MIC > 0.5 ug/ml DrugMatrix in vivo data: Biochemistry
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml DrugMatrix in vivo data: Hematology
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 64 ug/ml 24219991
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 24219991
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 24140948
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 24140948
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 24326278
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 24326278
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 64 ug/ml 24328269
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 24332656
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 24332656
NPT3165 Organism Micrococcus luteus NCTC 2665 Micrococcus luteus NCTC 2665 MIC = 3000 nM 24424132
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 16 ug/ml 10.1039/C3MD00125C
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 12 ug/ml 10.1039/C3MD00125C
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 32 ug/ml 10.1039/C3MD00193H
NPT3497 Organism Klebsiella sp. Klebsiella sp. MIC50 = 32 ug/ml 25453799
NPT3497 Organism Klebsiella sp. Klebsiella sp. MIC90 > 64 ug/ml 25453799
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 91.4 % 25644672
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 8 ug/ml 25599951
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 2 ug/ml 25599951
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 2 ug/ml 25599951
NPT19 Organism Escherichia coli Escherichia coli Activity = 98.1 % 25599951
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 256 ug/ml 26361737
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 26361737
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.15 ug/ml 26292628
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 26292628
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 26292628
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 256 ug/ml 26292628
NPT19 Organism Escherichia coli Escherichia coli Ratio = 2 26292628
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 256 ug/ml 10.1039/C4MD00279B
NPT5757 Organism Citrobacter koseri Citrobacter koseri MIC90 = 2 ug/ml 26291037
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC50 = 1 ug/ml 22694318
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 19848432
NPT19 Organism Escherichia coli Escherichia coli MIC <= 2 ug/ml 24405813
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 15104485
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 18557621
NPT766 Organism Proteus vulgaris Proteus vulgaris MIC50 = 2 ug/ml 18557621
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 11277756
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis IZ = 24 mm PubChem BioAssay data set
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis IZ = 25 mm PubChem BioAssay data set
NPT564 Organism Listeria monocytogenes Listeria monocytogenes IZ = 20 mm 18077363
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 18.6 % 18077363
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC = 2 ug/ml 23734701
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa FC >= 4 10924160
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 32 ug/ml 10924160
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 4 ug/ml 10924160
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC80 = 8 ug/ml 10924160
NPT19 Organism Escherichia coli Escherichia coli MIC > 64 ug/ml 10346956
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 64 ug/ml 16872140
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 16872140
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 16872140
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 16872140
NPT2911 Organism Pseudomonas putida Pseudomonas putida MIC = 1 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 24 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified MIC = 0.5 ug/ml 15974580
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 64 ug/ml 26854381
NPT2 Others Unspecified MIC = 16 ug/ml 20614907
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 32 ug/ml 20614907
NPT19 Organism Escherichia coli Escherichia coli MIC = 256 ug/ml 12502317
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv IC90 = 80 nM 9868159
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 17477572
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 25136754
NPT2895 Organism Providencia stuartii Providencia stuartii MIC = 16 ug/ml 7525959
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 19035792
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 23398362
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 512 ug/ml 23398362
NPT2 Others Unspecified MIC50 = 2 ug/ml 23398362
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.75 ug/ml 23398362
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 3 ug/ml 23398362
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 32 ug/ml 23398362
NPT3495 Organism Morganella morganii Morganella morganii Activity = 96 % 23398362
NPT2897 Organism Citrobacter freundii Citrobacter freundii Activity = 100 % 23398362
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv IC50 = 102 nM 23398362
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 32 ug/ml 23819826
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 32 ug/ml 23819826
NPT4381 Individual Protein Cell division protein ftsZ Escherichia coli K-12 Activity = 35 % 12828466
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 16643036
NPT5757 Organism Citrobacter koseri Citrobacter koseri MIC = 0.5 ug/ml 9873651
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml 9873651
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 8 ug/ml 18942825
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 8 ug/ml 9873651
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 9873651
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 4 ug/ml 9873651
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 25211032
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC50 = 32 ug/ml 18161942
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.9 ug/ml 18161942
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 9868159
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 4 ug/ml 20430633
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 0 % 20430633
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 50 ug/ml 16989519
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC = 12 ug/ml 12713408
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 17844994
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 17844994
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4 ug/ml 17844994
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 22691179
NPT1264 Organism Burkholderia cepacia Burkholderia cepacia Activity = 4 % 22691179
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 17417907
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 8 ug/ml 17363259
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 20153644
NPT2 Others Unspecified MIC = 4 ug/ml 20153644
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 12444673
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 32 ug/ml 17503850
NPT1101 Organism Staphylococcus aureus subsp. aureus RN4220 Staphylococcus aureus subsp. aureus RN4220 MIC = 4 ug/ml 17503850
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.5 ug/ml 17503850
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 4 ug/ml 21846091
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 4 ug/ml 21761866
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 21761866
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 100 ug/ml 21761866
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 100 ug/ml 21846091
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes Activity = 100 % 21761866
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 15332848
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 1.5 ug/ml 11408531
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 2 ug/ml 24571273
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 24571273
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Activity = 36 % 12036352
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 8 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 > 64 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 32 ug/ml 22194678
NPT19 Organism Escherichia coli Escherichia coli MIC < 2 ug/ml 22194678
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 22194678
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 32 ug/ml 23756062
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC <= 0.03 ug/ml 12443782
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.06 ug/ml 11806727
NPT314 Organism Bacillus cereus Bacillus cereus IZ = 20 mm 12213073
NPT314 Organism Bacillus cereus Bacillus cereus IZ = 20 mm 13678413
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 2657065
NPT4200 Organism Serratia liquefaciens Serratia liquefaciens MIC = 4 ug/ml 11206438
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 1597862
NPT2 Others Unspecified MIC50 > 128 ug/ml 15055999
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 1 ug/ml 14980653
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 10.1016/S0960-894X(01)81211-7
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC90 = 4 ug/ml 17070063
NPT3495 Organism Morganella morganii Morganella morganii MIC90 = 2 ug/ml 17070063
NPT19 Organism Escherichia coli Escherichia coli MIC = 8540 nM 17400457
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 32 ug/ml 11374952
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC90 > 128 ug/ml 12502314
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC >= 64 ug/ml 19284751
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC = 0.5 ug/ml 19222165
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 18571774
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 19282186
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC = 1 ug/ml 12880315
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC50 = 4 ug/ml 18512987
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 15787461
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 1 ug/ml 19105653
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 18922036
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 20088608
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 24 ug/ml 20088608
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 64 ug/ml 20361799
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 2 ug/ml 20362359
NPT2 Others Unspecified MIC > 32 ug/ml 20813948
NPT2 Others Unspecified MIC > 32 ug/ml 19949061
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 20684562
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 64 ug/ml 20684562
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 20684562
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 6 ug/ml 20684562
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 8 ug/ml 20684562
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 96 ug/ml 20684562
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 2 ug/ml 20086162
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 2 ug/ml 20350951
NPT2 Others Unspecified Activity = 59 % 21041091
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 20951034
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 20971006
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 20971006
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 18426954
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 18426954
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 0.9 ug/ml 19667291
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MBC = 2 ug/ml 19651905
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 64 ug/ml 19015351
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 19435664
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 21517059
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 128 ug/ml 22182577
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 0.5 ug/ml 22182577
NPT3496 Organism Enterobacter Enterobacter Activity = 2 % 22608675
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC50 = 2 ug/ml 22781704
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 22771008
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 22749280
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC = 64 ug/ml 22858300
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.5 ug/ml 24900509
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 23354072
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 4 ug/ml 23354072
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 23353738
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 23517371
NPT2911 Organism Pseudomonas putida Pseudomonas putida MIC > 32 ug/ml 10.1039/C0MD00267D
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 24904967
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC = 0.25 ug/ml 24914738
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.06 ug/ml 24914738
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC90 = 16 ug/ml 24974345
NPT3189 Organism Haemophilus parainfluenzae Haemophilus parainfluenzae MIC90 = 8 ug/ml 25062007
NPT3147 Organism Kocuria rhizophila Kocuria rhizophila MIC = 3420 nM 25137549
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 2 ug/ml 25284252
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 10.6019/CHEMBL3392926
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 6.7 % 25881827
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 0 % 25881827
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 25746816
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 25801154
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 2.6 % 25801154
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 24926807
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 25791675
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 32 ug/ml 25920564
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 25654185
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 25654185
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 26005918
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 26005918
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 21051535
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 21051535
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv EC90 = 0.08 nM 25763602
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 64 ug/ml 26403929
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 23398362
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 23398362
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 23398362
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC90 > 128 ug/ml 23398362
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 23398362
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca Activity = 100 % 23398362
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 100 % 23398362
NPT19 Organism Escherichia coli Escherichia coli Activity = 100 % 23398362
NPT19 Organism Escherichia coli Escherichia coli Activity = 71 % 23398362
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 69 % 23398362
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 95 % 23398362
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes Activity = 100 % 23398362
NPT19 Organism Escherichia coli Escherichia coli Activity = 98 % 23398362
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 12350140
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 20579892
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 20590148
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 9873492
NPT19 Organism Escherichia coli Escherichia coli Activity = 98.5 % 16417306
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 66 % 16417306
NPT19 Organism Escherichia coli Escherichia coli Activity = 59.5 % 16417306
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 98.6 % 16417306
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 75 % 16417306
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 92.7 % 16417306
NPT19 Organism Escherichia coli Escherichia coli MIC <= 0.5 ug/ml 20450170
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 24164206
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC <= 2 ug/ml 10217729
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC = 32 ug/ml 10217729
NPT2898 Organism Acinetobacter lwoffii Acinetobacter lwoffii MIC >= 64 ug/ml 10217729
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 100 ug/ml 16562826
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 32 ug/ml 25637363
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 22934671
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 8 ug/ml 7964781
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 20570529
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 20570529
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC < 2 ug/ml 20570529
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 20570529
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 64 ug/ml 22781190
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 22781190
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 22781190
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 64 ug/ml 25740159
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 10869203
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae Activity = 4.2 % 10924176
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 32 ug/ml 19835393
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 24582402
NPT172 Organism Proteus mirabilis Proteus mirabilis Activity = 63.6 % 22694318
NPT5757 Organism Citrobacter koseri Citrobacter koseri Activity = 35.7 % 22694318
NPT19 Organism Escherichia coli Escherichia coli Activity = 83.3 % 22694318
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 21256013
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv EC90 = 0.12 nM 20666364
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 8 ug/ml 25237727
NPT19 Organism Escherichia coli Escherichia coli IZ = 21.27 mm 16297615
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 12828466
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 12828466
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 12828466
NPT4080 Organism Acinetobacter sp. Acinetobacter sp. MIC > 32 ug/ml 11141096
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 23354070
NPT6506 Organism Enterobacter gergoviae Enterobacter gergoviae MIC = 2 ug/ml 23354070
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 2 ug/ml 23354070
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 25089583
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 21970540
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 3 ug/ml PubChem BioAssay data set
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.5 ug/ml 19256529
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC50 = 2 ug/ml 18440233
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC90 > 128 ug/ml 25978960
NPT5757 Organism Citrobacter koseri Citrobacter koseri MIC90 = 64 ug/ml 25978960
NPT19 Organism Escherichia coli Escherichia coli MIC <= 2 ug/ml 16919944
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 4 ug/ml 23734701
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 24709561
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 24709561
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC > 0.5 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 2 ug/ml PubChem BioAssay data set
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC90 = 4 ug/ml 10.1021/np50070a027
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC50 = 8 ug/ml 23268742
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 256 ug/ml 10075797
NPT19 Organism Escherichia coli Escherichia coli IZ = 22 mm 26358281
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 16 mm 20061160
NPT314 Organism Bacillus cereus Bacillus cereus IZ = 32 mm 20061160
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 16 mm 20061160
NPT2 Others Unspecified MIC = 1 ug/ml 22342628
NPT2 Others Unspecified MIC90 = 8 ug/ml 16252907
NPT766 Organism Proteus vulgaris Proteus vulgaris MIC90 = 8 ug/ml 18722127
NPT144 Individual Protein Telomerase reverse transcriptase Homo sapiens Inhibition = 25 % PubChem BioAssay data set
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 3.5 % 23145884
NPT2 Others Unspecified MIC = 0.5 ug/ml 25497963
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 15730238
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 32 ug/ml 25856683
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 160 nM 11858750
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv EC90 = 0.14 nM 12502327
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MBC = 8 ug/ml PubChem BioAssay data set
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC50 = 2 ug/ml PubChem BioAssay data set
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC50 = 2 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MBC = 4 ug/ml PubChem BioAssay data set
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MBC = 1 ug/ml PubChem BioAssay data set
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 16 ug/ml 25856683
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.5 ug/ml 16933872
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC90 > 128 ug/ml 18500841
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 23691978
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 17672504
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 8 ug/ml 2016726
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 17261619
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 16 ug/ml 17353252
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC > 128 ug/ml 17576842
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 64 ug/ml 17517838
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC = 0.25 ug/ml 19423196
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 2 ug/ml 20056520
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC > 1 ug/ml 20056520
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 19805565
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 19805565
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC = 4 ug/ml 19805554
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 4 ug/ml 19805554
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC = 4 ug/ml 19805554
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 19805554
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 19805554
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 64 ug/ml 19805554
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 19805554
NPT729 Organism Micrococcus luteus Micrococcus luteus MIC = 14000 nM 19884381
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4 ug/ml 20308368
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.9 ug/ml 20547814
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC90 = 2 ug/ml 20547814
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC90 = 4 ug/ml 20547814
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 20547814
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC90 = 8 ug/ml 19349512
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 0 % 19258280
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 78 % 19258280
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 19258280
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 3000 nM 19770287
NPT19 Organism Escherichia coli Escherichia coli MIC = 3000 nM 19770287
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 8 ug/ml 20566763
NPT2904 Organism Streptococcus equinus Streptococcus equinus MIC = 64 ug/ml 19620332
NPT19 Organism Escherichia coli Escherichia coli MIC = 12 ug/ml 20231393
NPT2895 Organism Providencia stuartii Providencia stuartii MIC = 0.5 ug/ml 20805391
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 20805391
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 81 % 21397370
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 83.3 % 21397370
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae MIC90 > 256 ug/ml DrugMatrix in vitro pharmacology data
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 16 ug/ml DrugMatrix in vitro pharmacology data
NPT19 Organism Escherichia coli Escherichia coli MIC = 12 ug/ml DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 85000 nM DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 10.1007/s00044-013-0779-x
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC50 = 64 ug/ml DrugMatrix in vivo data: Pathology
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium IZ = 19 mm DrugMatrix in vivo data: Pathology
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MBC = 1 ug/ml DrugMatrix in vivo data: Pathology
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml DrugMatrix in vivo data: Pathology
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 256 ug/ml DrugMatrix in vivo data: Biochemistry
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml DrugMatrix in vivo data: Hematology
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml DrugMatrix in vivo data: Hematology
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml DrugMatrix in vivo data: Hematology
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 2 ug/ml DrugMatrix in vivo data: Hematology
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml DrugMatrix in vivo data: Hematology
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 64 ug/ml DrugMatrix in vivo data: Hematology
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml DrugMatrix in vivo data: Hematology
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml DrugMatrix in vivo data: Hematology
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 16499313
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 2.3 ug/ml 16499313
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 22980217
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml 17417907
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 20718475
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 0.5 ug/ml 17711347
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 18973387
NPT2 Others Unspecified MIC50 = 2 ug/ml 15482936
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 100 % PubChem BioAssay data set
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 25226228
NPT1248 Organism Serratia marcescens Serratia marcescens MIC > 0.5 ug/ml 25226228
NPT3495 Organism Morganella morganii Morganella morganii MIC = 0.5 ug/ml 25226228
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ < 20 mm 18341287
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC >= 32 ug/ml 7807122
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv IC90 = 0.08 ug/ml 18177012
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 18780 nM PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 9213587
NPT5768 Organism Acinetobacter pittii Acinetobacter pittii MIC >= 16 ug/ml 11473434
NPT564 Organism Listeria monocytogenes Listeria monocytogenes MIC = 6 ug/ml 10.1016/S0960-894X(97)10101-9
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 12 ug/ml 15990295
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 6 ug/ml 2453615
NPT19 Organism Escherichia coli Escherichia coli Activity = 87 % PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC <= 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 4 ug/ml DrugMatrix in vitro pharmacology data
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 8 ug/ml DrugMatrix in vitro pharmacology data
NPT2895 Organism Providencia stuartii Providencia stuartii MIC = 8 ug/ml DrugMatrix in vitro pharmacology data
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml PubChem BioAssay data set
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC90 > 128 ug/ml 23848163
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 23822611
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 17 mm 26938998
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 2 ug/ml 23046382
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 0.5 ug/ml 23999046
NPT2 Others Unspecified MIC = 0.5 ug/ml 23999046
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 23999046
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 23999046
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 4 ug/ml 23999046
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 4 ug/ml 9461657
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 9461657
NPT172 Organism Proteus mirabilis Proteus mirabilis Activity = 100 % 10346948
NPT1248 Organism Serratia marcescens Serratia marcescens Activity = 96.3 % 10217714
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 2 ug/ml 26110443
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 2 ug/ml 10924188
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 2 ug/ml 15104490
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis Activity = 98.8 % 18070971
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 16472241
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC > 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT19 Organism Escherichia coli Escherichia coli Activity = 7 % DrugMatrix in vitro pharmacology data
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 1.5 ug/ml PubChem BioAssay data set
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 256 ug/ml 15100168
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml DrugMatrix in vivo data: Biochemistry
NPT5312 Organism Staphylococcus warneri Staphylococcus warneri MIC < 0.25 ug/ml 20930123
NPT2 Others Unspecified MIC50 = 8 ug/ml 18440233
NPT2 Others Unspecified MIC90 > 64 ug/ml 18440233
NPT2902 Organism Mycobacterium abscessus Mycobacterium abscessus MIC = 32 ug/ml 2724305
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 8 ug/ml 19344127
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 16 ug/ml 19344127
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 8 ug/ml 22295871
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 8 ug/ml 26295746
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 30 ug/ml 17118653
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC = 30 ug/ml 17118653
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 30 ug/ml 17118653
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 19000 nM 17118653
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 17287127
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 18952419
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 19 % 24767839
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 9 % 24767839
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 7400822
NPT2894 Organism Providencia rettgeri Providencia rettgeri MIC90 = 32 ug/ml 16643028
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC90 = 32 ug/ml 16643028
NPT5770 Organism Pasteurella sp. Pasteurella sp. Activity = 31 % 23992864
NPT1248 Organism Serratia marcescens Serratia marcescens Activity = 100 % 23992864
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 96 % 16933872
NPT172 Organism Proteus mirabilis Proteus mirabilis Activity = 100 % 16933872
NPT4080 Organism Acinetobacter sp. Acinetobacter sp. Activity = 31 % 16933872
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia Activity = 31 % 16933872
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens Activity = 31 % 16933872
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 17480098
NPT1248 Organism Serratia marcescens Serratia marcescens MIC50 > 128 ug/ml 12608846
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 8 ug/ml PubChem BioAssay data set
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1 ug/ml DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 85380 nM DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC > 32 ug/ml DrugMatrix in vitro pharmacology data
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 1 ug/ml 26214125
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 200 nM 19674906
NPT19 Organism Escherichia coli Escherichia coli Activity = 4 % 19674906
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 37.5 ug/ml 17850214
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC = 160 nM 14738378
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC = 64 ug/ml 12398531
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MBC = 32 ug/ml 12398531
NPT5772 Organism Enterobacter hormaechei Enterobacter hormaechei MIC = 4 ug/ml 12398531
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 12398531
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 20 mm 12646019
NPT3495 Organism Morganella morganii Morganella morganii MIC90 = 4 ug/ml 15711537
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 15711537
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 15711537
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.75 ug/ml 18434145
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 32 ug/ml 18077425
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC >= 250 ug/ml 18077425
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae MIC90 > 64 ug/ml 18077425
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 32 ug/ml 18077425
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC <= 2 ug/ml 18077425
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 64 ug/ml 18077425
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC < 4 ug/ml 18077425
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 16 ug/ml 18077425
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 18077425
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1 ug/ml 18183025
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 16 ug/ml 18183025
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 2 ug/ml 18183025
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1.6 ug/ml 18183025
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 3.2 ug/ml 18183025
NPT2 Others Unspecified MIC = 3000 nM 18183025
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 18 ug/ml 20156689
NPT19 Organism Escherichia coli Escherichia coli MIC = 512 ug/ml 20166671
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 MIC >= 256 ug/ml 20350806
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 512 ug/ml 20350806
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 18 ug/ml 20350806
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC = 13 ug/ml 20570526
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 1 ug/ml 20570526
NPT3699 Organism Pseudomonas sp. Pseudomonas sp. MIC = 0.5 ug/ml 18849971
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC90 = 2 ug/ml 19654408
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC90 = 2 ug/ml 19654408
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 19654408
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 19654408
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC > 128 ug/ml 19654408
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 19654408
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 19654408
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 19654408
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 19654408
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC50 = 8 ug/ml 22037378
NPT5757 Organism Citrobacter koseri Citrobacter koseri MIC50 = 32 ug/ml 22037378
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 4 ug/ml 22037378
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae Activity = 0 % 22037378
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 4 ug/ml 22130133
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 22130133
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 2 ug/ml 22130133
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 22770610
NPT5757 Organism Citrobacter koseri Citrobacter koseri Activity = 100 % 22749189
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 22749189
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT19 Organism Escherichia coli Escherichia coli MIC > 64 ug/ml 10.6019/CHEMBL1201861
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 10.6019/CHEMBL1201861
NPT2 Others Unspecified Ratio = 1 10.6019/CHEMBL1201861
NPT19 Organism Escherichia coli Escherichia coli IZ = 17 mm 10.6019/CHEMBL1201861
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC50 = 4 ug/ml 25089810
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC50 = 128 ug/ml 25064347
NPT19 Organism Escherichia coli Escherichia coli MIC = 128 ug/ml 25087753
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv Inhibition = 97.3 % PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 27311894
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 27311894
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 8201311
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 8201311
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 8201311
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 12828488
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC < 2 ug/ml PubChem BioAssay data set
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 8 ug/ml 21907578
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 64 ug/ml 20392109
NPT19 Organism Escherichia coli Escherichia coli Activity = 53.7 % 9834146
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 15387645
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 15387645
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 15387645
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 4 ug/ml 1294697
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC > 1024 ug/ml 18841903
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.5 ug/ml 26034885
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 26034885
NPT16 Organism Staphylococcus aureus Staphylococcus aureus IZ = 18 mm 23316950
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 16 ug/ml 20795741
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 8 ug/ml 20795741
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 4 ug/ml 20795741
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC < 2 ug/ml 24164206
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 32 ug/ml 24164206
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 17480098
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC >= 250 ug/ml 10.1039/C3MD00097D
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 6 ug/ml 15679321
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 21705225
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1 ug/ml 11678666
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 17309300
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 8 ug/ml 20155971
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 2 ug/ml 20155971
NPT19 Organism Escherichia coli Escherichia coli MIC = 16 ug/ml 24216090
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml 24216090
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 8699189
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 8699189
NPT19 Organism Escherichia coli Escherichia coli MIC = 64 ug/ml 8699189
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 23755850
NPT19 Organism Escherichia coli Escherichia coli MIC <= 0.03 ug/ml 23755850
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 85.3 % 19938815
NPT3163 Organism Acinetobacter calcoaceticus Acinetobacter calcoaceticus Activity = 48 % 19938815
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 64 ug/ml 23327668
NPT19 Organism Escherichia coli Escherichia coli MIC50 = 1 ug/ml 23327668
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 32 ug/ml 2016706
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 2016706
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 2 ug/ml 2016706
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 13 ug/ml 2016706
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 18.6 % DrugMatrix in vitro pharmacology data
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 4.9 % DrugMatrix in vitro pharmacology data
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 0 % DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 95.6 % DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 82 % DrugMatrix in vitro pharmacology data
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC = 4 ug/ml DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 19 % DrugMatrix in vitro pharmacology data
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 0.125 ug/ml DrugMatrix in vitro pharmacology data
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml DrugMatrix in vitro pharmacology data
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MBC = 0.009 nM PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 6000 nM PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MBC = 0.006 nM PubChem BioAssay data set
NPT5757 Organism Citrobacter koseri Citrobacter koseri MIC50 = 1 ug/ml PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli IZ = 14 mm 17850214
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC <= 2 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 17 mm PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 8 ug/ml 8388467
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 1 ug/ml 2374153
NPT3699 Organism Pseudomonas sp. Pseudomonas sp. MIC > 2 ug/ml 2374153
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 128 ug/ml 2374153
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv IC50 = 70 nM 2824776
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 2 ug/ml 17189664
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 18448342
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 64 ug/ml 18023934
NPT1246 Organism Salmonella Salmonella MIC50 = 2 ug/ml 18718695
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 1 ug/ml 18070975
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 19581101
NPT602 Organism Mycobacterium smegmatis Mycobacterium smegmatis MIC <= 0.03 ug/ml 18955515
NPT1248 Organism Serratia marcescens Serratia marcescens MIC90 = 8 ug/ml 19332671
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 256 ug/ml 19805572
NPT766 Organism Proteus vulgaris Proteus vulgaris MIC = 0.5 ug/ml 16472241
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 2 ug/ml DrugMatrix in vitro pharmacology data
NPT2897 Organism Citrobacter freundii Citrobacter freundii MIC = 2 ug/ml DrugMatrix in vitro pharmacology data
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml DrugMatrix in vitro pharmacology data
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml DrugMatrix in vitro pharmacology data
NPT19 Organism Escherichia coli Escherichia coli MIC = 4 ug/ml DrugMatrix in vitro pharmacology data
NPT19 Organism Escherichia coli Escherichia coli MBC = 4 ug/ml DrugMatrix in vitro pharmacology data
NPT19 Organism Escherichia coli Escherichia coli MBC = 16 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC90 = 8 ug/ml DrugMatrix in vitro pharmacology data
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC = 64 ug/ml DrugMatrix in vitro pharmacology data
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC = 1 ug/ml 10.1007/s00044-011-9810-2
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Activity = 53 % PubChem BioAssay data set
NPT1466 Organism Escherichia coli K12 Escherichia coli K-12 IZ = 18 mm DrugMatrix in vivo data: Pathology
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % DrugMatrix in vivo data: Pathology
NPT2 Others Unspecified MIC50 = 2 ug/ml DrugMatrix in vivo data: Pathology
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 25766629
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 128 ug/ml 25812965
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 = 16 ug/ml 26479031
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 20022253
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 24697496
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC50 = 8 ug/ml 22705001
NPT2903 Organism Mycobacterium chelonae Mycobacterium chelonae MIC90 = 8 ug/ml 22705001
NPT5757 Organism Citrobacter koseri Citrobacter koseri MIC = 1 ug/ml 9249968
NPT1246 Organism Salmonella Salmonella MIC = 0.5 ug/ml PubChem BioAssay data set
NPT1248 Organism Serratia marcescens Serratia marcescens MIC = 0.5 ug/ml 12762801
NPT729 Organism Micrococcus luteus Micrococcus luteus MIC = 13650 nM 12762801
NPT3145 Organism Bacillus subtilis subsp. spizizenii ATCC 6633 Bacillus subtilis subsp. spizizenii ATCC 6633 MIC = 72000 nM 12762801
NPT4997 Organism Klebsiella oxytoca Klebsiella oxytoca MIC = 2 ug/ml 12762801
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC > 256 ug/ml 12762801
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 16562830
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 1 ug/ml 16562830
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 1 ug/ml 24507923
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 24507923
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 24507923
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml PubChem BioAssay data set
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC50 = 8 ug/ml 23501116
NPT172 Organism Proteus mirabilis Proteus mirabilis MIC90 = 64 ug/ml 23501116
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC90 > 32 ug/ml 17629328
NPT19 Organism Escherichia coli Escherichia coli MIC = 50 ug/ml 24261937
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 100 ug/ml 10346940
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC = 0.5 ug/ml 23957453
NPT19 Organism Escherichia coli Escherichia coli MIC = 2 ug/ml 15387656
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 2 ug/ml 12350139
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 1 ug/ml 12350139
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 12350139
NPT1033 Organism Enterobacter cloacae Enterobacter cloacae MIC <= 2 ug/ml 10869199
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC50 = 1 ug/ml 11743742
NPT19 Organism Escherichia coli Escherichia coli Activity = 100 % 18494522
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 17922551
NPT19 Organism Escherichia coli Escherichia coli Activity = 0 % 14510593
NPT19 Organism Escherichia coli Escherichia coli Activity = 17 % 14510593
NPT3495 Organism Morganella morganii Morganella morganii Activity = 100 % 17665951
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 50 % 17665951
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 20 % 17665951
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 0 % 17665951
NPT172 Organism Proteus mirabilis Proteus mirabilis Activity = 0 % 17665951
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis IZ = 33 mm 17665951
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC = 64 ug/ml 17665951
NPT1245 Organism Streptococcus pasteurianus Streptococcus pasteurianus MIC = 32 ug/ml 17665951
NPT1245 Organism Streptococcus pasteurianus Streptococcus pasteurianus MIC = 512 ug/ml 17665951
NPT1245 Organism Streptococcus pasteurianus Streptococcus pasteurianus MIC = 64 ug/ml 17665951
NPT1245 Organism Streptococcus pasteurianus Streptococcus pasteurianus MIC = 128 ug/ml 17665951
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 3 ug/ml 17665951
NPT19 Organism Escherichia coli Escherichia coli Activity = 81 % 21182258
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Activity = 81 % 21182258
NPT19 Organism Escherichia coli Escherichia coli MIC = 12 ug/ml 15787444
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC <= 2 ug/ml 20695427
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 2 ug/ml 20194700
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.25 ug/ml 18955520
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 18955520
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 18955520
NPT19 Organism Escherichia coli Escherichia coli MIC = 0.5 ug/ml 18955520
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC = 2 ug/ml 18955520
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 256 ug/ml 18955520
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC90 = 32 ug/ml 19349520
NPT6019 Organism Nocardia nova Nocardia nova MIC = 0.00012 ug/ml 19349520
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC > 1024 ug/ml 20585136
NPT2905 Organism Nocardia farcinica Nocardia farcinica MIC < 1 ug/ml 20585136
NPT1176 Organism Mycobacterium fortuitum Mycobacterium fortuitum MIC90 = 2 ug/ml 19721074
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 128 ug/ml 22137458
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 64 ug/ml 10.1039/C2MD20300F
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 256 ug/ml 22584254
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 8 ug/ml 20738102
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC = 8 ug/ml PubChem BioAssay data set
NPT3699 Organism Pseudomonas sp. Pseudomonas sp. Activity = 90.9 % PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Activity = 100 % PubChem BioAssay data set
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 15165138
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 2 ug/ml 15165138
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 4 ug/ml 15165138
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 0.5 ug/ml 15165138
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC50 = 4 ug/ml 18077363
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 > 64 ug/ml 18077363
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa IZ = 22.1 mm 18077363
NPT5739 Organism Enterobacteriaceae Enterobacteriaceae Activity = 29.7 % 21458113
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 32 ug/ml 21377877
NPT19 Organism Escherichia coli Escherichia coli MIC50 <= 8 ug/ml 25443644
NPT19 Organism Escherichia coli Escherichia coli MIC90 = 16 ug/ml 25443644
NPT19 Organism Escherichia coli Escherichia coli MIC > 256 ug/ml 9548847
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 9548847
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 32 ug/ml 22858297
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 12 ug/ml 22858297
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 3 ug/ml 22858297
NPT1548 Organism Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC = 12 ug/ml 1708405
NPT19 Organism Escherichia coli Escherichia coli MIC = 1 ug/ml 26476666
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 26287548
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC = 8 ug/ml 26287401

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC330590 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.9205 High Similarity NPC314007
0.9205 High Similarity NPC477060
0.9205 High Similarity NPC123746
0.9205 High Similarity NPC314408
0.9205 High Similarity NPC43850
0.9 High Similarity NPC176381
0.9 High Similarity NPC195969
0.8778 High Similarity NPC214376
0.871 High Similarity NPC315334
0.8667 High Similarity NPC313552
0.8636 High Similarity NPC263058
0.8523 High Similarity NPC315969
0.8367 Intermediate Similarity NPC315036
0.8182 Intermediate Similarity NPC471628
0.8182 Intermediate Similarity NPC56298
0.809 Intermediate Similarity NPC318258
0.7978 Intermediate Similarity NPC316807
0.75 Intermediate Similarity NPC121479
0.75 Intermediate Similarity NPC57436
0.7475 Intermediate Similarity NPC328646
0.7429 Intermediate Similarity NPC221148
0.7172 Intermediate Similarity NPC470284
0.7143 Intermediate Similarity NPC306838
0.7143 Intermediate Similarity NPC241597
0.7128 Intermediate Similarity NPC70574
0.7079 Intermediate Similarity NPC223174
0.7079 Intermediate Similarity NPC327753
0.7079 Intermediate Similarity NPC327486
0.7071 Intermediate Similarity NPC470282
0.7021 Intermediate Similarity NPC98750
0.6979 Remote Similarity NPC36927
0.6979 Remote Similarity NPC271772
0.6961 Remote Similarity NPC208537
0.6961 Remote Similarity NPC270005
0.6939 Remote Similarity NPC476523
0.6932 Remote Similarity NPC129100
0.6932 Remote Similarity NPC291650
0.6932 Remote Similarity NPC322801
0.6827 Remote Similarity NPC470283
0.6807 Remote Similarity NPC94319
0.6771 Remote Similarity NPC100204
0.6771 Remote Similarity NPC83248
0.6735 Remote Similarity NPC165119
0.6724 Remote Similarity NPC313813
0.6701 Remote Similarity NPC471420
0.6606 Remote Similarity NPC42320
0.6606 Remote Similarity NPC188453
0.6495 Remote Similarity NPC150557
0.6486 Remote Similarity NPC314413
0.6486 Remote Similarity NPC314398
0.6486 Remote Similarity NPC239705
0.6476 Remote Similarity NPC61894
0.6476 Remote Similarity NPC475603
0.646 Remote Similarity NPC59589
0.6436 Remote Similarity NPC125253
0.6436 Remote Similarity NPC253975
0.6436 Remote Similarity NPC192025
0.6429 Remote Similarity NPC62845
0.6429 Remote Similarity NPC189854
0.6429 Remote Similarity NPC166242
0.6429 Remote Similarity NPC322449
0.6429 Remote Similarity NPC92874
0.6392 Remote Similarity NPC314772
0.6392 Remote Similarity NPC314968
0.6373 Remote Similarity NPC83839
0.6372 Remote Similarity NPC10897
0.6372 Remote Similarity NPC325900
0.6228 Remote Similarity NPC475918
0.6216 Remote Similarity NPC271207
0.6216 Remote Similarity NPC206711
0.6216 Remote Similarity NPC225978
0.6216 Remote Similarity NPC255175
0.6174 Remote Similarity NPC317534
0.6129 Remote Similarity NPC20035
0.6091 Remote Similarity NPC189629
0.6019 Remote Similarity NPC473950
0.6019 Remote Similarity NPC473581
0.6019 Remote Similarity NPC111567
0.6019 Remote Similarity NPC309898
0.6019 Remote Similarity NPC15851
0.6019 Remote Similarity NPC182632
0.6019 Remote Similarity NPC263545
0.6019 Remote Similarity NPC473604
0.6019 Remote Similarity NPC186840
0.6019 Remote Similarity NPC475125
0.6019 Remote Similarity NPC282705
0.5965 Remote Similarity NPC477198
0.5926 Remote Similarity NPC74672
0.5926 Remote Similarity NPC242503
0.5926 Remote Similarity NPC139782
0.5926 Remote Similarity NPC209047
0.5926 Remote Similarity NPC43074
0.5909 Remote Similarity NPC23454
0.5909 Remote Similarity NPC262312
0.5909 Remote Similarity NPC192066
0.5909 Remote Similarity NPC17290
0.5909 Remote Similarity NPC157353
0.5909 Remote Similarity NPC282088
0.5909 Remote Similarity NPC70323
0.5909 Remote Similarity NPC54961
0.5909 Remote Similarity NPC35269
0.5909 Remote Similarity NPC158445
0.5909 Remote Similarity NPC256570
0.5909 Remote Similarity NPC156782
0.5909 Remote Similarity NPC3568
0.5906 Remote Similarity NPC68327
0.5888 Remote Similarity NPC292345
0.582 Remote Similarity NPC259586
0.5804 Remote Similarity NPC8098
0.5804 Remote Similarity NPC45313
0.5804 Remote Similarity NPC183449
0.5804 Remote Similarity NPC197294
0.5785 Remote Similarity NPC314306
0.5778 Remote Similarity NPC317023
0.5772 Remote Similarity NPC222481
0.5772 Remote Similarity NPC470621
0.5748 Remote Similarity NPC139857
0.5714 Remote Similarity NPC305261
0.57 Remote Similarity NPC244539
0.5667 Remote Similarity NPC472025
0.5659 Remote Similarity NPC75839
0.5644 Remote Similarity NPC313762
0.5641 Remote Similarity NPC55336
0.5638 Remote Similarity NPC41429
0.5612 Remote Similarity NPC476695
0.5612 Remote Similarity NPC476694
0.5612 Remote Similarity NPC476696
0.5604 Remote Similarity NPC290179
0.5604 Remote Similarity NPC34877

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC330590 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
1.0 High Similarity NPD5377 Approved
1.0 High Similarity NPD5378 Approved
1.0 High Similarity NPD5381 Approved
0.9205 High Similarity NPD3207 Approved
0.9205 High Similarity NPD3203 Approved
0.9205 High Similarity NPD3201 Approved
0.9205 High Similarity NPD3202 Approved
0.9205 High Similarity NPD3209 Approved
0.9205 High Similarity NPD3208 Approved
0.9091 High Similarity NPD3200 Clinical (unspecified phase)
0.9072 High Similarity NPD5376 Approved
0.9 High Similarity NPD5794 Approved
0.9 High Similarity NPD5795 Approved
0.9 High Similarity NPD5796 Clinical (unspecified phase)
0.9 High Similarity NPD5798 Approved
0.9 High Similarity NPD5797 Approved
0.8778 High Similarity NPD2698 Approved
0.8351 Intermediate Similarity NPD4282 Approved
0.8182 Intermediate Similarity NPD4837 Approved
0.8182 Intermediate Similarity NPD4836 Approved
0.8182 Intermediate Similarity NPD4835 Approved
0.8182 Intermediate Similarity NPD4838 Approved
0.8061 Intermediate Similarity NPD6428 Approved
0.7699 Intermediate Similarity NPD6436 Phase 3
0.7596 Intermediate Similarity NPD8045 Clinical (unspecified phase)
0.75 Intermediate Similarity NPD35 Approved
0.75 Intermediate Similarity NPD4833 Approved
0.7449 Intermediate Similarity NPD3716 Discontinued
0.7429 Intermediate Similarity NPD1450 Approved
0.7429 Intermediate Similarity NPD1449 Approved
0.7143 Intermediate Similarity NPD3731 Phase 3
0.7117 Intermediate Similarity NPD2690 Discontinued
0.7079 Intermediate Similarity NPD9445 Approved
0.7037 Intermediate Similarity NPD2700 Approved
0.7018 Intermediate Similarity NPD4831 Approved
0.7018 Intermediate Similarity NPD4830 Approved
0.7018 Intermediate Similarity NPD4832 Approved
0.6937 Remote Similarity NPD6941 Approved
0.6932 Remote Similarity NPD9031 Approved
0.6932 Remote Similarity NPD9030 Approved
0.6932 Remote Similarity NPD9033 Approved
0.6932 Remote Similarity NPD9032 Approved
0.6807 Remote Similarity NPD4828 Approved
0.6807 Remote Similarity NPD4827 Approved
0.6807 Remote Similarity NPD4826 Approved
0.6733 Remote Similarity NPD4759 Clinical (unspecified phase)
0.6697 Remote Similarity NPD7139 Approved
0.6697 Remote Similarity NPD7141 Clinical (unspecified phase)
0.6697 Remote Similarity NPD7140 Approved
0.6667 Remote Similarity NPD9034 Approved
0.6667 Remote Similarity NPD67 Phase 2
0.6638 Remote Similarity NPD3204 Clinical (unspecified phase)
0.6571 Remote Similarity NPD1446 Phase 3
0.6571 Remote Similarity NPD1447 Phase 3
0.6422 Remote Similarity NPD2255 Approved
0.6404 Remote Similarity NPD8174 Phase 2
0.6392 Remote Similarity NPD9435 Approved
0.6392 Remote Similarity NPD9434 Approved
0.6182 Remote Similarity NPD881 Approved
0.6055 Remote Similarity NPD8394 Approved
0.6017 Remote Similarity NPD8087 Discontinued
0.5926 Remote Similarity NPD8522 Clinical (unspecified phase)
0.59 Remote Similarity NPD3160 Suspended
0.5888 Remote Similarity NPD618 Clinical (unspecified phase)
0.5856 Remote Similarity NPD7844 Discontinued
0.584 Remote Similarity NPD8345 Approved
0.584 Remote Similarity NPD8346 Approved
0.584 Remote Similarity NPD8347 Approved
0.581 Remote Similarity NPD361 Discontinued
0.5785 Remote Similarity NPD6430 Approved
0.5785 Remote Similarity NPD6429 Approved
0.5781 Remote Similarity NPD591 Approved
0.5781 Remote Similarity NPD577 Phase 3
0.5776 Remote Similarity NPD1407 Approved
0.5652 Remote Similarity NPD6123 Approved
0.5644 Remote Similarity NPD372 Clinical (unspecified phase)
0.563 Remote Similarity NPD8307 Discontinued
0.5607 Remote Similarity NPD394 Phase 3

Structure

External Identifiers

PubChem CID   37768
ChEMBL   CHEMBL177
ZINC  

Physicochemical Properties

Molecular Weight:  585.29
ALogP:  -8.5812
MLogP:  1.9
XLogP:  -6.078
# Rotatable Bonds:  23
Polar Surface Area:  335.43
# H-Bond Aceptor:  18
# H-Bond Donor:  13
# Rings:  3
# Heavy Atoms:  40

Download Data

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Structure MOL file  
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Similar NPs/Drugs