TCM-ID Component

Description of the Component

Component ID	TCMH1072
Latin Name	Semen arecae preparata
English Name	Charred areca seed
Chinese Pinyin Name	Jiao Bing Lang
中文名	ç„¦æ§Ÿæ¦”
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions	promote digestion and relax bowels
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID	ITSAA732-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMF500	Da Li Tong Granules	è¾¾ç«‹é€šé¢—ç²’
TCMF190	Er Tong Qing Re Dao Zhi Pills	å„¿ç«¥æ¸…çƒå¯¼æ»žä¸¸
TCMF3934	Er Tong Qing Re Dao Zhi Pills	å„¿ç«¥æ¸…çƒå¯¼æ»žä¸¸
TCMFx4217	Jian Pi Xiao Shi Pills	å¥è„¾æ¶ˆé£Ÿä¸¸
TCMF4302	Jian Shen Xiao Dao Infusion	å¥èº«æ¶ˆå¯¼å†²å‰‚
TCMF907	Jian Wei Tablet	å¥èƒƒç‰‡
TCMFx4836	Kai Xiong Li Qi Pills	å¼€èƒ¸ç†æ°”ä¸¸
TCMFx4378	Nv Bao Capsules	å¥³å®èƒ¶å›Š
TCMF1053	Pi Wei Shu Pills	è„¾èƒƒèˆ’ä¸¸
TCMF4585	Pi Wei Shu Pills	è„¾èƒƒèˆ’ä¸¸
TCMFx3597	Shen Rong Lu Tai Ointment	å‚èŒ¸é¹¿èƒŽè†
TCMF5326	Shu Gan Ping Wei Pills	èˆ’è‚å¹³èƒƒä¸¸
TCMF1046	Shu Gan Ping Wei Pills	èˆ’è‚å¹³èƒƒä¸¸
TCMFx6717	Xiao Er Hua Shi Pills	å°å„¿åŒ–é£Ÿä¸¸
TCMFx237	Xiao Er HuaÂ ShiÂ Oral Liquid	å°å„¿åŒ–é£Ÿå£æœæ¶²
TCMFx238	Xiao Er HuaÂ ShiÂ Pills	å°å„¿åŒ–é£Ÿä¸¸
TCMFx6497	Xiao Er Zeng Shi Pills	å°å„¿å¢žé£Ÿä¸¸
TCMF6558	Xiao Er Zhi Sou Pills	å°å„¿æ¢å—½ä¸¸
TCMFx6549	Xiao Er Zhi Sou Syrup	å°å„¿æ¢å—½ç³–æµ†
TCMFx235	Xiao Er Zhi Sou Syrup	å°å„¿æ¢å—½ç³–æµ†

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT1	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Transferase	Q96KQ7
TCMT267	GABRR1	GABA receptor rho-1 subunit	Ion channel	P24046
TCMT27	DRD1	Dopamine D1 receptor	GPCR	P21728
TCMT290	CHRM5	Muscarinic acetylcholine receptor M5	GPCR	P08912
TCMT292	CHRM1	Muscarinic acetylcholine receptor M1	GPCR	P11229
TCMT293	CHRM2	Muscarinic acetylcholine receptor M2	GPCR	P08172
TCMT551	CHRM4	Muscarinic acetylcholine receptor M4	GPCR	P08173
TCMT69	THRB	Thyroid hormone receptor beta-1	Nuclear receptor	P10828

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC719
Formula: C8H13NO2

Common Name	Arecoline
IUPAC Name	methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate
Canonical SMILES	COC(=O)C1=CCCN(C1)C
Standard InCHI	InChI=1S/C8H13NO2/c1-9-5-3-4-7(6-9)8(10)11-2/h4H,3,5-6H2,1-2H3
Standard InCHIKey	HJJPJSXJAXAIPN-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL7303]; PubChem [2230];
Reference of Component-Ingredient Pair	17418620

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH357	Pericarpium arecae	Da Fu Pi	å¤§è…¹çš®
TCMH1072	Semen arecae preparata	Jiao Bing Lang	ç„¦æ§Ÿæ¦”
TCMH358	Areca catechu	Da Fu Zi	å¤§è…¹å
TCMH182	Areca catechu	Bing Lang	æ§Ÿæ¦”

Ingredient ID: TCMC1393
Formula: C6H9NO2

Common Name	Isoguvacine
IUPAC Name	1,2,3,6-tetrahydropyridine-4-carboxylic acid
Canonical SMILES	OC(=O)C1=CCNCC1
Standard InCHI	InChI=1S/C6H9NO2/c8-6(9)5-1-3-7-4-2-5/h1,7H,2-4H2,(H,8,9)
Standard InCHIKey	KRVDMABBKYMBHG-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL39071]; PubChem [3765];
Reference of Component-Ingredient Pair	22529813

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1072	Semen arecae preparata	Jiao Bing Lang	ç„¦æ§Ÿæ¦”
TCMH358	Areca catechu	Da Fu Zi	å¤§è…¹å
TCMH182	Areca catechu	Bing Lang	æ§Ÿæ¦”

Ingredient ID: TCMC1300
Formula: C6H9NO2

Common Name	Guvacine
IUPAC Name	1,2,3,6-tetrahydropyridin-1-ium-5-carboxylate
Canonical SMILES	OC(=O)C1=CCCNC1
Standard InCHI	InChI=1S/C6H9NO2/c8-6(9)5-2-1-3-7-4-5/h2,7H,1,3-4H2,(H,8,9)
Standard InCHIKey	QTDZOWFRBNTPQR-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL76768]; PubChem [40468028];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH357	Pericarpium arecae	Da Fu Pi	å¤§è…¹çš®
TCMH1072	Semen arecae preparata	Jiao Bing Lang	ç„¦æ§Ÿæ¦”
TCMH358	Areca catechu	Da Fu Zi	å¤§è…¹å
TCMH182	Areca catechu	Bing Lang	æ§Ÿæ¦”
TCMH2079	Garcinia morella	Teng Huang	è—¤é»„

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom
TCMC719	C8H13NO2	Arecoline	155.09	0.1341	2.01	0.172	3	0	29.54	4	1	11
TCMC1300	C6H9NO2	Guvacine	127.06	-0.6528	1.79	0.041	3	2	49.33	2	1	9
TCMC1393	C6H9NO2	Isoguvacine	127.06	-0.1092	1.79	-0.388	3	2	49.33	2	1	9

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Semen arecae preparata ç„¦æ§Ÿæ¦”

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC719

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1393

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1300

Occurrence of the ingredient across TCM components

Properties

Download Data