Natural Product Target: DNA topoisomerase I

Target ID:   NPT143
Target Name:   DNA topoisomerase I
Target Type:   Individual Protein
Organism of Target:   Homo sapiens
Target External ID:   Uniprot_ID:[ P11387]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC129909 Camptothecin 87
NPC316461 Simocyclinone D8 7
NPC1203 Rebeccamycin 5
NPC192674 9-Aminocamptothecin 5
NPC261012 Doxorubicin 5
NPC246943 Kaempferol 3-O-Beta-D-Glucopyranosyl-7-O-Alpha-L-Rhamnopyranoside 3
NPC472207 n.a. 3
NPC142415 Oleanolic_Acid 2
NPC129897 Lamellarin D 2
NPC25998 Aesculioside Iv-23D1 2
NPC151781 Hydroxycamptothecin 2
NPC246693 Shikonin 2
NPC247779 Echinatin 2
NPC470003 Sid4253497 2
NPC119094 Chebulagic Acid 2
NPC185498 Etoposide 2
NPC476477 [(1R)-1-(5,8-Dihydroxy-1,4-Dioxonaphthalen-2-Yl)-4-Methylpent-3-Enyl] Pentanoate 1
NPC276377 Kaempferol 3-O-Alpha-L-Arabinopyranosyl-7-O-Alpha-L-Rhamnopyranoside 1
NPC476473 [(1R)-1-(5,8-Dihydroxy-1,4-Dioxonaphthalen-2-Yl)-4-Methylpent-3-Enyl] Benzoate 1
NPC16520 20(S)-Ginsenoside Rg2 1
NPC241349 Isobutylshikonin 1
NPC31700 Staurosporine Aglycon 1
NPC31907 Ginsenoside F2 1
NPC69737 Gypenoside Xvii 1
NPC471602 [(1R)-1-(5,8-Dihydroxy-1,4-Dioxonaphthalen-2-Yl)-4-Methylpent-3-Enyl] Pent-4-Enoate 1
NPC27765 Alpha-Amyrin 1
NPC279121 Luteolin 1
NPC473945 Halenaquinol Sulfate Sodium 1
NPC169749 Myricetin 1
NPC424 Elaidic Acid 1
NPC8039 20(R)Ginsenoside Rg3 1
NPC207866 n.a. 1
NPC185529 Oleanderolide 1
NPC285829 Plumbagin 1
NPC88923 Reserpine 1
NPC175602 Tsitsikammamine A 1
NPC189852 20(R)-Ginsenoside Rg2 1
NPC32641 Kaempferol 3-O-[Alpha-L-Rhamnopyranosyl(1->2)-Beta-D-Galactopyranosyl]-7-O-Alpha-L-Rhamnopyranoside 1
NPC108288 Juglone 1
NPC50503 Isorauhimbinic Acid 1
NPC189903 Dicentrinone 1
NPC29771 Dimethylacrylshikonin 1
NPC299405 Acetylshikonin 1
NPC109403 Daunorubicin 1
NPC49196 Yohimbine 1
NPC195314 Staurosporinone 1
NPC256188 Kaempferol 3-O-[Alpha-L-Rhamnopyranosyl(1->2)-Beta-D-Glucopyranosyl]-7-O-Alpha-L-Rhamnopyranoside 1
NPC311092 Ganoderiol F 1
NPC110609 Alkannin 1
NPC208477 Ginsenoside Rd 1
NPC256463 [(1R)-1-(5,8-Dihydroxy-1,4-Dioxonaphthalen-2-Yl)-4-Methylpent-3-Enyl] Propanoate 1
NPC116458 Kaempferol 3-O-Beta-D-Galactopyranosyl-7-O-Alpha-L-Rhamnopyranoside 1
NPC306835 [(1R)-1-(5,8-Dihydroxy-1,4-Dioxonaphthalen-2-Yl)-4-Methylpent-3-Enyl] Butanoate 1
NPC208594 Ginsenoside Re 1
NPC258547 21-O-Angeloy-3Beta,16Alpha,22Alpha,24,28-Pentahydroxyolean-12-Ene 1
NPC40530 Netropsin 1
NPC192069 Helenaquinone 1
NPC208650 Ginsenoside Rb1 1
NPC30397 3-O-Beta-D-Glucopyranosyl Quinovic Acid28-O-Beta-D-Glucopyranosyl Ester 1
NPC61038 Tsitsikammamine B 1
NPC120123 (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-Hydroxy-17-[(2S)-2-Hydroxy-6-Methylhept-5-En-2-Yl]-4,4,8,10,14-Pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthren-3-Yl]Oxy]-6-(Hydroxymethyl)Oxan-3-Yl]Oxy-6-(Hydroxymethyl)Oxane-3,4,5-Triol 1
NPC213190 Ginsenoside F5 1
NPC126637 3,4,5-Trihydroxy-N-Phenylbenzamide 1
NPC215008 Naphthoquinone 1
NPC261831 Oleic Acid 1
NPC476157 n.a. 1
NPC131479 Ginsenoside F3 1
NPC216312 Acetylalkannin 1
NPC266084 (1R,2S)-1-(3,4-Dihydroxy-Phenyl)-6,7-Dihydroxy-1,2-Dihydro-Naphthalene-2,3-Dicarboxylic Acid Bis-[(R)-1-Carboxy-2-(3,4-Dihydroxy-Phenyl)-Ethyl] Ester 1
NPC72016 Kaempferol 3-O-(5-O-Acetyl-Alpha-D-Apiofuranosyl)-7-O-Alpha-L-Rhamnopyranoside 1
NPC14030 Corilagin 1
NPC83663 (1S,2R)-1-(3,4-Dihydroxy-Phenyl)-6,7-Dihydroxy-1,2-Dihydro-Naphthalene-2,3-Dicarboxylic Acid Bis-[(R)-1-Carboxy-2-(3,4-Dihydroxy-Phenyl)-Ethyl] Ester 1
NPC223125 Ungeremine 1
NPC270834 Stallimycin 1
NPC474659 Xestosaprol A 1
NPC14946 Ginsenoside Rb3 1
NPC167037 Damara-20(22), 24-Dien-3, 6, 12-Trine 1
NPC232178 Naphthazalin 1
NPC274507 3-O-Beta-D-Glucopyranosyl Quinovic Acid 1

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