Structure

Physi-Chem Properties

Molecular Weight:  210.13
Volume:  226.013
LogP:  1.276
LogD:  0.347
LogS:  -0.71
# Rotatable Bonds:  5
TPSA:  60.69
# H-Bond Aceptor:  3
# H-Bond Donor:  3
# Rings:  1
# Heavy Atoms:  3

MedChem Properties

QED Drug-Likeness Score:  0.689
Synthetic Accessibility Score:  2.886
Fsp3:  0.5
Lipinski Rule-of-5:  Accepted
Pfizer Rule:  Accepted
GSK Rule:  Accepted
BMS Rule:  0
Golden Triangle Rule:  Accepted
Chelating Alert:  0
PAINS Alert:  0

ADMET Properties (ADMETlab2.0)

ADMET: Absorption

Caco-2 Permeability:  -4.796
MDCK Permeability:  1.734349825710524e-05
Pgp-inhibitor:  0.0
Pgp-substrate:  0.995
Human Intestinal Absorption (HIA):  0.016
20% Bioavailability (F20%):  0.921
30% Bioavailability (F30%):  0.989

ADMET: Distribution

Blood-Brain-Barrier Penetration (BBB):  0.171
Plasma Protein Binding (PPB):  32.36809539794922%
Volume Distribution (VD):  4.29
Pgp-substrate:  60.66810989379883%

ADMET: Metabolism

CYP1A2-inhibitor:  0.47
CYP1A2-substrate:  0.624
CYP2C19-inhibitor:  0.26
CYP2C19-substrate:  0.526
CYP2C9-inhibitor:  0.109
CYP2C9-substrate:  0.942
CYP2D6-inhibitor:  0.143
CYP2D6-substrate:  0.417
CYP3A4-inhibitor:  0.022
CYP3A4-substrate:  0.323

ADMET: Excretion

Clearance (CL):  11.972
Half-life (T1/2):  0.864

ADMET: Toxicity

hERG Blockers:  0.05
Human Hepatotoxicity (H-HT):  0.19
Drug-inuced Liver Injury (DILI):  0.02
AMES Toxicity:  0.012
Rat Oral Acute Toxicity:  0.033
Maximum Recommended Daily Dose:  0.899
Skin Sensitization:  0.576
Carcinogencity:  0.19
Eye Corrosion:  0.045
Eye Irritation:  0.968
Respiratory Toxicity:  0.057

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General Info & Identifiers & Properties  
Structure MOL file  
Source Organisms  
Biological Activities  
Similar NPs/Drugs  

  Natural Product: NPC191693

Natural Product ID:  NPC191693
Common Name*:   NQDJXKOVJZTUJA-UHFFFAOYSA-N
IUPAC Name:   n.a.
Synonyms:  
Standard InCHIKey:  NQDJXKOVJZTUJA-UHFFFAOYSA-N
Standard InCHI:  InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)
SMILES:  Cc1ccnc2c1N=C(c1cccnc1N2C1CC1)O
Synthetic Gene Cluster:   n.a.
ChEMBL Identifier:   n.a.
PubChem CID:   4463
Chemical Classification**:  
  • CHEMONTID:0000000 [Organic compounds]
    • [CHEMONTID:0004707] Organic nitrogen compounds
      • [CHEMONTID:0000278] Organonitrogen compounds
        • [CHEMONTID:0002449] Amines
          • [CHEMONTID:0002452] Tertiary amines
            • [CHEMONTID:0002454] Tertiary alkylarylamines
              • [CHEMONTID:0003902] Alkyldiarylamines

*Note: the InCHIKey will be temporarily assigned as the "Common Name" if no IUPAC name or alternative short name is available.
**Note: the Chemical Classification was calculated by NPClassifier Version 1.5. Reference: PMID:34662515.

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO16360 Gardenia carinata Species Rubiaceae Eukaryota Leaves; Twigs n.a. n.a. PMID[23550966]
NPO41042 Stachybotrys chartarum MXH-X73 Strain Stachybotryaceae Eukaryota n.a. n.a. n.a. PMID[24308675]
NPO5865 Justicia gendarussa Species Acanthaceae Eukaryota n.a. n.a. n.a. PMID[28613071]
NPO4554 Isatis tinctoria Species Brassicaceae Eukaryota Roots n.a. n.a. PMID[32004936]
NPO4554 Isatis tinctoria Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO4554 Isatis tinctoria Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO4554 Isatis tinctoria Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO5865 Justicia gendarussa Species Acanthaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO16360 Gardenia carinata Species Rubiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO4554 Isatis tinctoria Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[UNPD]

☑ Note for Reference:
In addition to directly collecting NP source organism data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated them from below databases:
☉ UNPD: Universal Natural Products Database [PMID: 23638153].
☉ StreptomeDB: a database of streptomycetes natural products [PMID: 33051671].
☉ TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine [PMID: 26156871].
☉ TCM@Taiwan: a Traditional Chinese Medicine database [PMID: 21253603].
☉ TCMID: a Traditional Chinese Medicine database [PMID: 29106634].
☉ TCMSP: The traditional Chinese medicine systems pharmacology database and analysis platform [PMID: 24735618].
☉ HerDing: a herb recommendation system to treat diseases using genes and chemicals [PMID: 26980517].
☉ MetaboLights: a metabolomics database [PMID: 27010336].
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

  NP Quantity Composition/Concentration

Organism ID NP ID Organism Material Preparation Organism Part NP Quantity (Standard) NP Quantity (Minimum) NP Quantity (Maximum) Quantity Unit Reference

☑ Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP quantitative records for specific NP domains (e.g., NPS from foods or herbs) from domain-specific databases. These databases include:
☉ DUKE: Dr. Duke's Phytochemical and Ethnobotanical Databases.
☉ PHENOL EXPLORER: is the first comprehensive database on polyphenol content in foods [PMID: 24103452], its homepage can be accessed at here.
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 23000.0 nM PMID[10386942]
NPT25 Cell Line MT4 Homo sapiens IC50 = 96.0 nM PMID[14971897]
NPT25 Cell Line MT4 Homo sapiens IC50 = 17200.0 nM PMID[14971897]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 230.0 nM PMID[14971897]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 73.0 nM PMID[7678654]
NPT25 Cell Line MT4 Homo sapiens IC95 = 100.0 nM PMID[7678654]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 6440.0 nM PMID[8648604]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 400.0 nM PMID[11462972]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 9000.0 nM PMID[11462972]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 7000.0 nM PMID[11462972]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 10000.0 nM PMID[11462972]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 36000.0 nM PMID[11462972]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 18000.0 nM PMID[11462972]
NPT25 Cell Line MT4 Homo sapiens EC50 = 120.0 nM PMID[7527463]
NPT25 Cell Line MT4 Homo sapiens EC50 > 80000.0 nM PMID[7527463]
NPT404 Cell Line CCRF-CEM Homo sapiens EC50 = 110.0 nM PMID[7527463]
NPT404 Cell Line CCRF-CEM Homo sapiens EC50 > 80000.0 nM PMID[7527463]
NPT25 Cell Line MT4 Homo sapiens CC50 > 80000.0 nM PMID[7527463]
NPT25 Cell Line MT4 Homo sapiens Ratio > 625.0 n.a. PMID[7527463]
NPT25 Cell Line MT4 Homo sapiens IC95 = 100.0 nM PMID[1716683]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Activity = 0.03 uM PMID[12086483]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[11597403]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 70.0 nM PMID[11597403]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 26.0 nM PMID[11597403]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 53.0 nM PMID[11597403]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 20.0 nM PMID[11597403]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 100.0 nM PMID[11597403]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 30.0 nM PMID[11597403]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 380.0 nM PMID[11597403]
NPT25 Cell Line MT4 Homo sapiens IC50 = 600.0 nM PMID[15109677]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 84.0 nM DOI[10.1016/0960-894X(94)00478-X]
NPT25 Cell Line MT4 Homo sapiens CC50 > 376000.0 nM PMID[7650679]
NPT25 Cell Line MT4 Homo sapiens EC50 = 300.0 nM PMID[7650679]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1.3 nM PMID[10514285]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 130.0 nM PMID[10514285]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 114.0 nM PMID[10514285]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 625.0 nM PMID[10514285]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ED50 = 0.176 uM PMID[10514285]
NPT25 Cell Line MT4 Homo sapiens ED50 > 5.0 uM PMID[10514285]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ED50 > 5.0 uM PMID[10514285]
NPT25 Cell Line MT4 Homo sapiens CC50 > 300000.0 nM PMID[9154967]
NPT25 Cell Line MT4 Homo sapiens EC50 = 250.0 nM PMID[9154967]
NPT5821 Individual Protein Glutathione S-transferase Mu 1 Mus musculus Ratio > 1200.0 n.a. PMID[9154967]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 270.0 nM PMID[9154967]
NPT1452 Cell Line C8166 Homo sapiens EC50 > 100000.0 nM PMID[9154967]
NPT759 Cell Line H9 Homo sapiens EC50 > 100000.0 nM PMID[9154967]
NPT25 Cell Line MT4 Homo sapiens EC50 > 100000.0 nM PMID[9154967]
NPT25 Cell Line MT4 Homo sapiens EC50 = 310.0 nM PMID[9154967]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 3100.0 nM PMID[8809165]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 320.0 nM PMID[8809165]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 60000.0 nM PMID[8809165]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 200.0 nM PMID[11052800]
NPT25 Cell Line MT4 Homo sapiens CC50 > 200000.0 nM PMID[10052969]
NPT25 Cell Line MT4 Homo sapiens EC50 = 250.0 nM PMID[10052969]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 300.0 nM PMID[10052969]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 61.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 222.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 180.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 5.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 1440.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 1880.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 70.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 8270.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 8300.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 207.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 8.0 nM PMID[11708913]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 29.0 nM PMID[11708913]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 400.0 nM PMID[10543890]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 9000.0 nM PMID[10543890]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 7000.0 nM PMID[10543890]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 10000.0 nM PMID[10543890]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 36000.0 nM PMID[10543890]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 18000.0 nM PMID[10543890]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1850.0 nM PMID[9685236]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1480.0 nM PMID[9685236]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 3930.0 nM PMID[9685236]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 80.0 nM PMID[9685236]
NPT165 Cell Line HeLa Homo sapiens IC50 = 89.0 nM PMID[11384233]
NPT165 Cell Line HeLa Homo sapiens IC50 = 7100.0 nM PMID[11384233]
NPT165 Cell Line HeLa Homo sapiens IC50 ~ 10000.0 nM PMID[11384233]
NPT165 Cell Line HeLa Homo sapiens IC50 > 10000.0 nM PMID[11384233]
NPT165 Cell Line HeLa Homo sapiens IC50 = 72.0 nM PMID[11384233]
NPT165 Cell Line HeLa Homo sapiens IC50 = 340.0 nM PMID[11384233]
NPT165 Cell Line HeLa Homo sapiens IC50 = 2200.0 nM PMID[11384233]
NPT165 Cell Line HeLa Homo sapiens IC50 = 10000.0 nM PMID[11384233]
NPT165 Cell Line HeLa Homo sapiens IC50 = 56.0 nM PMID[11384233]
NPT165 Cell Line HeLa Homo sapiens IC50 > 50000.0 nM PMID[11384233]
NPT165 Cell Line HeLa Homo sapiens IC50 = 21000.0 nM PMID[11384233]
NPT609 Individual Protein Human immunodeficiency virus type 1 protease Human immunodeficiency virus 1 IC50 = 101.0 nM PMID[7683725]
NPT25 Cell Line MT4 Homo sapiens IC95 = 400.0 nM PMID[7683725]
NPT609 Individual Protein Human immunodeficiency virus type 1 protease Human immunodeficiency virus 1 IC50 = 57900.0 nM PMID[7683725]
NPT609 Individual Protein Human immunodeficiency virus type 1 protease Human immunodeficiency virus 1 IC50 = 11300.0 nM PMID[7683725]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4848.0 nM PMID[10673109]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 6440.0 nM DOI[10.1016/S0960-894X(00)80468-0]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2110.0 nM DOI[10.1016/S0960-894X(00)80468-0]
NPT759 Cell Line H9 Homo sapiens IC90 = 78.0 nM DOI[10.1016/S0960-894X(00)80468-0]
NPT1452 Cell Line C8166 Homo sapiens IC100 = 0.1 uM DOI[10.1016/S0960-894X(00)80468-0]
NPT25 Cell Line MT4 Homo sapiens EC50 = 30.0 nM PMID[9767646]
NPT25 Cell Line MT4 Homo sapiens CC50 = 683000.0 nM PMID[9767646]
NPT25 Cell Line MT4 Homo sapiens CC50 < 300000.0 nM PMID[8558522]
NPT25 Cell Line MT4 Homo sapiens EC50 = 300.0 nM PMID[8558522]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 600.0 nM PMID[8558522]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 20000.0 nM PMID[8558522]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 3500.0 nM PMID[8558522]
NPT25 Cell Line MT4 Homo sapiens Ratio > 1000.0 n.a. PMID[8558522]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 80.0 nM PMID[7490732]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2600.0 nM PMID[7490732]
NPT1452 Cell Line C8166 Homo sapiens IC50 = 40.0 nM PMID[7490732]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 130.0 nM PMID[7490732]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1900.0 nM PMID[7490732]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 110.0 nM PMID[7490732]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 430.0 nM PMID[7681480]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4848.0 nM PMID[10821714]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC90 = 100.0 nM PMID[10821714]
NPT25 Cell Line MT4 Homo sapiens CC50 > 100000.0 nM PMID[15239667]
NPT1452 Cell Line C8166 Homo sapiens EC90 = 0.12 uM PMID[15239667]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1900.0 nM PMID[9685235]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 80.0 nM PMID[9685235]
NPT25 Cell Line MT4 Homo sapiens CC50 > 200000.0 nM PMID[11472208]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 300.0 nM PMID[11472208]
NPT25 Cell Line MT4 Homo sapiens EC50 = 370.0 nM PMID[11472208]
NPT25 Cell Line MT4 Homo sapiens EC50 > 30000.0 nM PMID[11472208]
NPT25 Cell Line MT4 Homo sapiens CC50 > 200000.0 nM DOI[10.1016/S0960-894X(97)00340-5]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 250.0 nM DOI[10.1016/S0960-894X(97)00340-5]
NPT25 Cell Line MT4 Homo sapiens EC50 = 370.0 nM PMID[14761194]
NPT25 Cell Line MT4 Homo sapiens EC50 > 30000.0 nM PMID[14761194]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 200.0 nM PMID[8523406]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ED50 = 0.15 uM PMID[8523406]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 CD50 = 188.0 uM PMID[8523406]
NPT25 Cell Line MT4 Homo sapiens CC50 > 200000.0 nM PMID[10794705]
NPT25 Cell Line MT4 Homo sapiens EC50 = 350.0 nM PMID[10794705]
NPT25 Cell Line MT4 Homo sapiens IC50 = 640000.0 nM PMID[10794705]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 23000.0 nM PMID[10999473]
NPT759 Cell Line H9 Homo sapiens IC50 = 5000.0 nM PMID[10999473]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 6000.0 nM PMID[12593657]
NPT25 Cell Line MT4 Homo sapiens IC50 > 10.0 ug.mL-1 PMID[7538590]
NPT25 Cell Line MT4 Homo sapiens IC50 = 0.22 ug.mL-1 PMID[7538590]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 430.0 nM PMID[7689109]
NPT460 Cell Line MT2 Homo sapiens IC50 = 303.0 nM PMID[7689109]
NPT25 Cell Line MT4 Homo sapiens IC50 = 32.0 nM PMID[11527703]
NPT25 Cell Line MT4 Homo sapiens IC50 = 316.0 nM PMID[11527703]
NPT25 Cell Line MT4 Homo sapiens IC50 = 6310.0 nM PMID[11527703]
NPT25 Cell Line MT4 Homo sapiens IC50 = 5010.0 nM PMID[11527703]
NPT25 Cell Line MT4 Homo sapiens IC50 = 10000.0 nM PMID[11527703]
NPT25 Cell Line MT4 Homo sapiens IC50 > 100000.0 nM PMID[11527703]
NPT25 Cell Line MT4 Homo sapiens IC50 = 7940.0 nM PMID[11527703]
NPT25 Cell Line MT4 Homo sapiens CD50 > 100.0 uM PMID[12477355]
NPT25 Cell Line MT4 Homo sapiens IC50 = 32.0 nM PMID[14643315]
NPT25 Cell Line MT4 Homo sapiens IC50 = 6300.0 nM PMID[14643315]
NPT25 Cell Line MT4 Homo sapiens IC50 > 10000.0 nM PMID[14643315]
NPT25 Cell Line MT4 Homo sapiens IC50 = 10000.0 nM PMID[14643315]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 84.0 nM PMID[11170624]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 3100.0 nM PMID[10715167]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 320.0 nM PMID[10715167]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 = 84.0 nM PMID[8676342]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 84.0 nM PMID[7537334]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 200.0 nM PMID[8863804]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 11800.0 nM PMID[8863804]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 201000.0 nM PMID[8863804]
NPT25 Cell Line MT4 Homo sapiens ED50 = 0.15 uM PMID[8863804]
NPT25 Cell Line MT4 Homo sapiens ED50 = 0.62 uM PMID[8863804]
NPT25 Cell Line MT4 Homo sapiens ED50 = 22.0 uM PMID[8863804]
NPT25 Cell Line MT4 Homo sapiens ED50 = 8.0 uM PMID[8863804]
NPT25 Cell Line MT4 Homo sapiens ED50 > 10.0 uM PMID[8863804]
NPT25 Cell Line MT4 Homo sapiens IC95 = 100.0 nM PMID[1279173]
NPT25 Cell Line MT4 Homo sapiens EC50 = 300.0 nM PMID[10698447]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 100000.0 nM PMID[11229762]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 23000.0 nM PMID[10509923]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 500.0 nM PMID[8709096]
NPT1452 Cell Line C8166 Homo sapiens IC50 = 40.0 nM DOI[10.1016/0960-894X(95)00257-T]
NPT1452 Cell Line C8166 Homo sapiens CC50 = 321000.0 nM DOI[10.1016/0960-894X(95)00257-T]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 250.0 nM PMID[15149669]
NPT25 Cell Line MT4 Homo sapiens CC50 > 200000.0 nM PMID[15149669]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 73.0 nM PMID[7520079]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 93.0 % PMID[7684450]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 5500.0 nM PMID[7684450]
NPT460 Cell Line MT2 Homo sapiens CC50 > 10000.0 nM PMID[7684450]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 100.0 % PMID[1712395]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 84.0 nM PMID[1712395]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 85.0 % PMID[7490733]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 59.0 % PMID[7490733]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 80.0 nM PMID[7490733]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2600.0 nM PMID[7490733]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 23000.0 nM PMID[10617082]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 60.0 nM PMID[9873507]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 3200.0 nM PMID[9873507]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 180.0 nM PMID[9873507]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1300.0 nM PMID[9873507]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 170.0 nM PMID[9873507]
NPT25 Cell Line MT4 Homo sapiens EC50 = 128.0 nM PMID[1501224]
NPT25 Cell Line MT4 Homo sapiens CC50 > 80000.0 nM PMID[1501224]
NPT25 Cell Line MT4 Homo sapiens EC50 = 73.0 nM PMID[7540208]
NPT25 Cell Line MT4 Homo sapiens CC50 = 290000.0 nM PMID[7540208]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 200.0 nM PMID[9873380]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 13000.0 nM PMID[9873380]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 160000.0 nM PMID[9873380]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 280.0 nM PMID[7504733]
NPT25 Cell Line MT4 Homo sapiens CC50 > 20.0 ug.mL-1 PMID[1495006]
NPT25 Cell Line MT4 Homo sapiens EC50 = 370.0 nM PMID[15634015]
NPT1452 Cell Line C8166 Homo sapiens EC90 = 0.12 uM PMID[15634015]
NPT25 Cell Line MT4 Homo sapiens EC50 > 30000.0 nM PMID[15634015]
NPT1452 Cell Line C8166 Homo sapiens EC90 > 30.0 uM PMID[15634015]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 3000.0 nM PMID[15686922]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 300.0 nM PMID[15537346]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 100000.0 nM PMID[15537346]
NPT165 Cell Line HeLa Homo sapiens IC50 = 2200.0 nM PMID[15537347]
NPT165 Cell Line HeLa Homo sapiens IC50 ~ 10000.0 nM PMID[15537347]
NPT165 Cell Line HeLa Homo sapiens IC50 > 10000.0 nM PMID[15537347]
NPT165 Cell Line HeLa Homo sapiens IC50 = 340.0 nM PMID[15537347]
NPT165 Cell Line HeLa Homo sapiens IC50 > 50000.0 nM PMID[15537347]
NPT165 Cell Line HeLa Homo sapiens IC50 = 21000.0 nM PMID[15537347]
NPT165 Cell Line HeLa Homo sapiens IC50 = 7100.0 nM PMID[15537347]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 250.0 nM PMID[15974590]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 0.4 uM PMID[15974590]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 9.0 uM PMID[15974590]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 7.0 uM PMID[15974590]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 36.0 uM PMID[15974590]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 0.3 uM PMID[15974590]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 18.0 uM PMID[15974590]
NPT25 Cell Line MT4 Homo sapiens EC50 = 32.0 nM PMID[15771411]
NPT25 Cell Line MT4 Homo sapiens EC50 = 320.0 nM PMID[15771411]
NPT25 Cell Line MT4 Homo sapiens EC50 = 6310.0 nM PMID[15771411]
NPT25 Cell Line MT4 Homo sapiens EC50 = 10000.0 nM PMID[15771411]
NPT25 Cell Line MT4 Homo sapiens EC50 > 100000.0 nM PMID[15771411]
NPT25 Cell Line MT4 Homo sapiens EC50 > 10000.0 nM PMID[15771411]
NPT1083 Cell Line A-375 Homo sapiens Inhibition = 35.0 % PMID[16250634]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 0.4 uM PMID[16335924]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 8.0 uM PMID[16335924]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 20.0 uM PMID[16335924]
NPT25 Cell Line MT4 Homo sapiens CC50 > 7500.0 nM PMID[16335924]
NPT460 Cell Line MT2 Homo sapiens CC50 > 10000.0 nM PMID[16263277]
NPT460 Cell Line MT2 Homo sapiens CC50 > 10000.0 nM PMID[16298131]
NPT71 Cell Line HEK293 Homo sapiens CC50 > 10000.0 nM PMID[16480865]
NPT71 Cell Line HEK293 Homo sapiens CC50 > 10000.0 nM PMID[16464578]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 60.0 nM PMID[16527484]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 5750.0 nM PMID[16527484]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 6650.0 nM PMID[16527484]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 860.0 nM PMID[16527484]
NPT25 Cell Line MT4 Homo sapiens CC50 > 7500.0 nM PMID[16621553]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 > 7500.0 nM PMID[16621553]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 3900.0 nM PMID[16621553]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 52.0 nM PMID[16621553]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 20.0 uM PMID[16621553]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 8.0 uM PMID[16621553]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 0.4 uM PMID[16621553]
NPT71 Cell Line HEK293 Homo sapiens CC50 > 10000.0 nM PMID[16632349]
NPT71 Cell Line HEK293 Homo sapiens CC50 > 10000.0 nM PMID[16782337]
NPT460 Cell Line MT2 Homo sapiens CC50 > 10000.0 nM PMID[16931015]
NPT25 Cell Line MT4 Homo sapiens CC50 > 200000.0 nM PMID[17381078]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 50.0 nM PMID[17116672]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Activity = 6.5 uM PMID[17116672]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 12000.0 nM PMID[17116672]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2000.0 nM PMID[17116672]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 75.0 % PMID[17116672]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 9000.0 nM PMID[16279773]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7000.0 nM PMID[16279773]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 10000.0 nM PMID[16279773]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 36000.0 nM PMID[16279773]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 18000.0 nM PMID[16279773]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1700.0 nM PMID[17458947]
NPT25 Cell Line MT4 Homo sapiens CC50 = 31631.0 nM PMID[17223230]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 9000.0 nM PMID[17803291]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 > 20000.0 nM PMID[17803291]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 7000.0 nM PMID[17803291]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 400.0 nM PMID[17803291]
NPT25 Cell Line MT4 Homo sapiens CC50 = 15000.0 nM PMID[17803290]
NPT404 Cell Line CCRF-CEM Homo sapiens CC50 > 50000.0 nM PMID[17321639]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2500.0 nM PMID[17321639]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 23000.0 nM PMID[17321639]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 180.0 nM PMID[17276064]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[17276064]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 10600.0 nM PMID[17870545]
NPT25 Cell Line MT4 Homo sapiens CC50 > 7000.0 nM PMID[17910429]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 400.0 nM PMID[17910429]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 7000.0 nM PMID[17910429]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 9000.0 nM PMID[17910429]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 10000.0 nM PMID[17910429]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 300.0 nM PMID[17910429]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 18000.0 nM PMID[17910429]
NPT460 Cell Line MT2 Homo sapiens CC50 > 10000.0 nM PMID[17918923]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 84.0 nM PMID[18083556]
NPT25 Cell Line MT4 Homo sapiens CC50 = 15000.0 nM PMID[18083556]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 84.0 nM PMID[18222088]
NPT25 Cell Line MT4 Homo sapiens CC50 = 15000.0 nM PMID[18222088]
NPT25 Cell Line MT4 Homo sapiens CC50 = 683000.0 nM PMID[17964796]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 5000.0 nM PMID[17172472]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 450.0 nM PMID[17172472]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 900.0 nM PMID[17172472]
NPT25 Cell Line MT4 Homo sapiens CC50 > 200000.0 nM PMID[17869386]
NPT404 Cell Line CCRF-CEM Homo sapiens CC50 > 50000.0 nM PMID[18420310]
NPT612 Individual Protein Canalicular multispecific organic anion transporter 1 Homo sapiens Activity = 121.0 % PMID[18457386]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Activity = 11.4 % PMID[18800765]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Activity = 21.7 % PMID[18800765]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1700.0 nM PMID[18800765]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 630.0 nM PMID[18800765]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 100000.0 nM PMID[18800765]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4.0 ug.mL-1 PMID[19091580]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 400.0 nM PMID[19170521]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 7000.0 nM PMID[19170521]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 9000.0 nM PMID[19170521]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 36000.0 nM PMID[19170521]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[18824350]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 0.4 uM PMID[19140683]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 8.0 uM PMID[19140683]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 20.0 uM PMID[19140683]
NPT25 Cell Line MT4 Homo sapiens CC50 > 7500.0 nM PMID[19140683]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 400.0 nM PMID[19140683]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 500.0 nM PMID[19140683]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 4000.0 nM PMID[19140683]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 5000.0 nM PMID[19140683]
NPT25 Cell Line MT4 Homo sapiens CC50 > 200000.0 nM PMID[18952324]
NPT25 Cell Line MT4 Homo sapiens CC50 > 7000.0 nM PMID[18630898]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 7.0 uM PMID[18630898]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 35.0 uM PMID[18630898]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 9.0 uM PMID[18630898]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 0.4 uM PMID[18630898]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 180.0 nM PMID[18585918]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[18585918]
NPT25 Cell Line MT4 Homo sapiens CC50 > 50000.0 nM PMID[18242784]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 100.0 % PMID[18242784]
NPT404 Cell Line CCRF-CEM Homo sapiens CC50 > 4000.0 nM PMID[18242784]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 180.0 nM PMID[19616956]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[19616956]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[19643613]
NPT25 Cell Line MT4 Homo sapiens CC50 > 100000.0 nM PMID[19775780]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 27100.0 nM PMID[20050672]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[19628308]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 180.0 nM PMID[20097079]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[20097079]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7000.0 nM PMID[20097079]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 30000.0 nM PMID[20097079]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4000.0 nM PMID[20097079]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 95.5 % PMID[20137956]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 3.6 nM PMID[20137956]
NPT460 Cell Line MT2 Homo sapiens CC50 > 100000.0 nM PMID[20304641]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[20307984]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4120.0 nM PMID[20347295]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4120.0 nM PMID[20371182]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 92.0 % PMID[20381364]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 0.37 ug.mL-1 PMID[20570527]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[20570527]
NPT25 Cell Line MT4 Homo sapiens CC50 >= 15000.0 nM PMID[20598556]
NPT25 Cell Line MT4 Homo sapiens CC50 = 683000.0 nM PMID[20638854]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 13200.0 nM PMID[20598780]
NPT25 Cell Line MT4 Homo sapiens Activity > 32.0 uM PMID[19933797]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 156000.0 nM PMID[20308384]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 3200.0 nM PMID[20308384]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 185000.0 nM PMID[20308384]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4100.0 nM PMID[20308384]
NPT315 Cell Line CEM-SS Homo sapiens TC50 > 1.0 uM PMID[20888224]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 137.0 nM PMID[19289522]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 8900.0 nM PMID[19289522]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 9300.0 nM PMID[19289522]
NPT25 Cell Line MT4 Homo sapiens CC50 = 156000.0 nM PMID[21093117]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 250.0 nM PMID[21093117]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 11000.0 nM PMID[19704127]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 1000000.0 nM PMID[19704127]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 700.0 nM PMID[19704127]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 67000.0 nM PMID[19704127]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 0.00009 ug.mL-1 PMID[21334901]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 0.00011 ug.mL-1 PMID[21334901]
NPT927 Cell Line PBMC Homo sapiens CC50 = 40.88 ug.mL-1 PMID[21334901]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 95.5 % PMID[21295891]
NPT404 Cell Line CCRF-CEM Homo sapiens CC50 > 10000000.0 nM PMID[21366296]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2000.0 nM PMID[21636271]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 9000.0 nM PMID[21636271]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7000.0 nM PMID[21636271]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 400.0 nM PMID[21636271]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[21683601]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4400.0 nM PMID[21683601]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 670.0 nM PMID[21700466]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Activity = 1.0 % PMID[21700466]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[21824782]
NPT1083 Cell Line A-375 Homo sapiens Activity = 35.0 % PMID[21755950]
NPT1083 Cell Line A-375 Homo sapiens Activity = 50.0 % PMID[21755950]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[21872971]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4390.0 nM PMID[21872971]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[21903401]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 1685000.0 nM PMID[21903401]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 1655000.0 nM PMID[21903401]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki > 1000000.0 nM PMID[21903401]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 99.2 % PMID[21982685]
NPT460 Cell Line MT2 Homo sapiens CC50 > 100000.0 nM PMID[22081993]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[22037050]
NPT460 Cell Line MT2 Homo sapiens CC50 > 100000.0 nM PMID[22269110]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 18000.0 nM PMID[21438533]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 400.0 nM PMID[21438533]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 35000.0 nM PMID[21438533]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 7000.0 nM PMID[21438533]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 9000.0 nM PMID[21438533]
NPT25 Cell Line MT4 Homo sapiens CC50 = 7510.0 nM PMID[21438533]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[22405288]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2740.0 nM PMID[22405288]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 99.92 % PMID[22480850]
NPT25 Cell Line MT4 Homo sapiens CC50 = 7500.0 nM PMID[22428851]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 400.0 nM PMID[22428851]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 7000.0 nM PMID[22428851]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 35000.0 nM PMID[22428851]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[22575532]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[22591854]
NPT25 Cell Line MT4 Homo sapiens CC50 > 5.0 ug.mL-1 PMID[22652226]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4120.0 nM PMID[22283377]
NPT25 Cell Line MT4 Homo sapiens CC50 = 325130.0 nM PMID[22283377]
NPT109 Individual Protein Cytochrome P450 3A4 Homo sapiens Ratio IC50 = 2.0 n.a. PMID[22931300]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[22883027]
NPT25 Cell Line MT4 Homo sapiens CC50 > 14990.0 nM PMID[23159806]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 9000.0 nM PMID[22712652]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7000.0 nM PMID[22712652]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 400.0 nM PMID[22712652]
NPT25 Cell Line MT4 Homo sapiens CC50 > 18776.0 nM PMID[22712652]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2700.0 nM PMID[23084898]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[23084898]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2700.0 nM PMID[23098609]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[23098609]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4.0 ug.mL-1 DOI[10.1007/s00044-011-9662-9]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM DOI[10.1007/s00044-009-9220-x]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4.0 ug.mL-1 DOI[10.1007/s00044-011-9664-7]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 500.0 nM DOI[10.1007/s00044-007-9004-0]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4.0 ug.mL-1 DOI[10.1007/s00044-011-9705-2]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4.0 ug.mL-1 DOI[10.1007/s00044-011-9776-0]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4.0 ug.mL-1 DOI[10.1007/s00044-013-0567-7]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4.0 ug.mL-1 DOI[10.1007/s00044-012-0129-4]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 99.92 % DOI[10.1007/s00044-012-0463-6]
NPT460 Cell Line MT2 Homo sapiens CC50 > 100000.0 nM PMID[23298809]
NPT25 Cell Line MT4 Homo sapiens CC50 = 325130.0 nM PMID[23540737]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4450.0 nM PMID[23540737]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7500.0 nM PMID[23550966]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki > 2000000.0 nM PMID[23357038]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 273000.0 nM PMID[23357038]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Ki = 7200.0 nM PMID[23357038]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4000.0 nM PMID[23357038]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1200.0 nM PMID[23415090]
NPT25 Cell Line MT4 Homo sapiens CC50 > 14900.0 nM PMID[23415090]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[23707918]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[23707918]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2740.0 nM PMID[23707918]
NPT460 Cell Line MT2 Homo sapiens CC50 > 100000.0 nM PMID[23937980]
NPT460 Cell Line MT2 Homo sapiens CC50 > 100000.0 nM PMID[23899617]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 6200.0 nM PMID[24119448]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[24119448]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1780.0 nM PMID[24055077]
NPT25 Cell Line MT4 Homo sapiens CC50 = 15020.0 nM PMID[24055077]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 510.0 nM PMID[24239481]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1700.0 nM PMID[24134904]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[24134904]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 1700.0 nM PMID[24308675]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[24239481]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 670.0 nM PMID[24275349]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[24457088]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2550.0 nM PMID[24457088]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2500.0 nM PMID[24581546]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[24581546]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[24602795]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1780.0 nM DOI[10.1039/C3MD00247K]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM DOI[10.1039/C3MD00247K]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM DOI[10.1039/C3MD00028A]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2740.0 nM DOI[10.1039/C3MD00028A]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 2000000.0 nM DOI[10.1039/C3MD00036B]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 273000.0 nM DOI[10.1039/C3MD00036B]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7200.0 nM DOI[10.1039/C3MD00036B]
NPT333 Cell Line CEM Homo sapiens CC50 > 25000.0 nM DOI[10.1039/C3MD00036B]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 2000000.0 nM DOI[10.1039/C3MD00225J]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition < 10.0 % DOI[10.1039/C3MD00225J]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 273000.0 nM DOI[10.1039/C3MD00225J]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 85.0 % DOI[10.1039/C3MD00225J]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 48.0 % DOI[10.1039/C3MD00225J]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7200.0 nM DOI[10.1039/C3MD00225J]
NPT25 Cell Line MT4 Homo sapiens CC50 > 14990.0 nM PMID[24631361]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 550.0 nM PMID[24631361]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1780.0 nM PMID[24680058]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[24680058]
NPT25 Cell Line MT4 Homo sapiens CC50 > 18776.0 nM PMID[24769348]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 400.0 nM PMID[24769348]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7000.0 nM PMID[24769348]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 9000.0 nM PMID[24769348]
NPT25 Cell Line MT4 Homo sapiens CC50 > 7000.0 nM PMID[24933420]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 0.4 uM PMID[24933420]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 7.0 uM PMID[24933420]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 35.0 uM PMID[24933420]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 9.0 uM PMID[24933420]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15021.0 nM PMID[24952305]
NPT25 Cell Line MT4 Homo sapiens CC50 = 15000.0 nM PMID[24794751]
NPT25 Cell Line MT4 Homo sapiens CC50 > 100000.0 nM PMID[24805780]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 4650.0 nM PMID[25468035]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[25089812]
NPT460 Cell Line MT2 Homo sapiens CC50 = 320000.0 nM PMID[25176328]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1350.0 nM PMID[25127466]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[25127466]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[25240095]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 620.0 nM PMID[25240095]
NPT460 Cell Line MT2 Homo sapiens CC50 > 100000.0 nM PMID[25408842]
NPT25 Cell Line MT4 Homo sapiens CC50 > 14400.0 nM PMID[25150090]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 900.0 nM PMID[25150090]
NPT25 Cell Line MT4 Homo sapiens CC50 > 18776.0 nM PMID[25418038]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 400.0 nM PMID[25418038]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7000.0 nM PMID[25418038]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 20000.0 nM PMID[25418038]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 9000.0 nM PMID[25418038]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 99.6 % PMID[25592712]
NPT165 Cell Line HeLa Homo sapiens CC50 > 4000.0 nM PMID[25682562]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[25537532]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1000.0 nM PMID[25537532]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[25638501]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1150.0 nM PMID[25638501]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[25626145]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 580.0 nM PMID[25626145]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[24926807]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[25707013]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2400.0 nM PMID[25707013]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1795.0 nM PMID[25935383]
NPT208 Individual Protein Cytochrome P450 1A2 Homo sapiens Inhibition < 10.0 % PMID[21467212]
NPT627 Individual Protein Cytochrome P450 2B6 Homo sapiens Inhibition < 10.0 % PMID[21467212]
NPT628 Individual Protein Cytochrome P450 2C8 Homo sapiens Inhibition < 10.0 % PMID[21467212]
NPT212 Individual Protein Cytochrome P450 2C9 Homo sapiens Inhibition < 10.0 % PMID[21467212]
NPT213 Individual Protein Cytochrome P450 2C19 Homo sapiens Inhibition = 12.0 % PMID[21467212]
NPT110 Individual Protein Cytochrome P450 2D6 Homo sapiens Inhibition < 10.0 % PMID[21467212]
NPT109 Individual Protein Cytochrome P450 3A4 Homo sapiens Inhibition < 10.0 % PMID[21467212]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[25946116]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 620.0 nM PMID[25907370]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[25907370]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 807.0 nM PMID[26162497]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Inhibition = 99.9 % PMID[26209833]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[26385446]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1528.0 nM PMID[26385446]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15021.0 nM PMID[26276435]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1650.0 nM PMID[26276435]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[26613134]
NPT708 Cell Line HuT78 Homo sapiens CC50 > 14000.0 nM PMID[26613134]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 8800.0 nM PMID[26802545]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 125.0 nM PMID[26898379]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[26994843]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 8800.0 nM PMID[26994843]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Activity = 9.0 % PMID[27108399]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 Activity = 13.7 % PMID[27108399]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 920.0 nM PMID[27108399]
NPT1045 Cell Line U2OS Homo sapiens CC50 > 100000.0 nM PMID[27108399]
NPT25 Cell Line MT4 Homo sapiens CC50 > 18000.0 nM PMID[27112451]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 910.0 nM PMID[27112451]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 14000.0 nM PMID[27112451]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 240000.0 nM PMID[27112451]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 375000.0 nM PMID[27112451]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[27234889]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 269900.0 nM PMID[27234889]
NPT25 Cell Line MT4 Homo sapiens CC50 = 4.0 ug.mL-1 PMID[27105027]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 > 100.0 ug.mL-1 PMID[27105027]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1350.0 nM PMID[27267005]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[27750153]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[28314598]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[28254696]
NPT612 Individual Protein Canalicular multispecific organic anion transporter 1 Homo sapiens IC50 > 133000.0 nM PMID[23956101]
NPT1249 Individual Protein Canalicular multispecific organic anion transporter 2 Homo sapiens IC50 > 133000.0 nM PMID[23956101]
NPT1028 Individual Protein Multidrug resistance-associated protein 4 Homo sapiens IC50 > 133000.0 nM PMID[23956101]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 240.0 nM PMID[28314514]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[28314514]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[28314514]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 400.0 nM PMID[28628334]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7000.0 nM PMID[28628334]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 20000.0 nM PMID[28628334]
NPT25 Cell Line MT4 Homo sapiens CC50 > 18776.0 nM PMID[28628334]
NPT927 Cell Line PBMC Homo sapiens IC50 = 40.0 nM PMID[28442262]
NPT927 Cell Line PBMC Homo sapiens TC50 >= 10.0 uM PMID[28442262]
NPT927 Cell Line PBMC Homo sapiens IC90 = 180.0 nM PMID[28442262]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 2100.0 nM PMID[28481112]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 5390.0 nM PMID[28481112]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[28481112]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 271.0 nM PMID[28481112]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15.0 nM PMID[28481112]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[28559060]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1550.0 nM PMID[28559060]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 14000.0 nM PMID[28559060]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 188000.0 nM PMID[28559060]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 > 375000.0 nM PMID[28559060]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1130.0 nM PMID[28559060]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1390.0 nM PMID[29152052]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4000.0 nM PMID[29353724]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 176.0 nM PMID[29353724]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[29635166]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1550.0 nM PMID[29291935]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[29291935]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 450.0 nM PMID[29291935]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 9590.0 nM PMID[29291935]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[29291935]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 75.0 nM PMID[29291935]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[28987601]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2320.0 nM PMID[28987601]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[29534929]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[29559197]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 900.0 nM PMID[29559197]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 2320.0 nM PMID[29670696]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 = 124.0 nM PMID[29670703]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 EC50 > 15020.0 nM PMID[29670703]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[29670703]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 590.0 nM PMID[29670703]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4000.0 nM PMID[30318436]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 323.0 nM PMID[30318436]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[31735575]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 320.0 nM PMID[31735575]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 595.0 nM PMID[30606670]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 105.0 nM PMID[30783503]
NPT2615 Cell Line HEK-293T Homo sapiens CC50 = 92700.0 nM PMID[30783503]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15030.0 nM PMID[31714780]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 404.0 nM PMID[31714780]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15030.0 nM PMID[31434039]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 590.0 nM PMID[31434039]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[30721060]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 595.0 nM PMID[30721060]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 588.84 nM PMID[30721060]
NPT25 Cell Line MT4 Homo sapiens CC50 > 7000.0 nM PMID[30525601]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 400.0 nM PMID[30525601]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 6800.0 nM PMID[30525601]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 33000.0 nM PMID[30525601]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 ID50 = 8500.0 nM PMID[30525601]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 181.0 nM PMID[31935327]
NPT460 Cell Line MT2 Homo sapiens CC50 > 100000.0 nM PMID[31281023]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 84.0 nM PMID[30516990]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1.9 nM PMID[31091477]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15030.0 nM PMID[31421633]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 404.0 nM PMID[31421633]
NPT927 Cell Line PBMC Homo sapiens CC50 = 1003000.0 nM PMID[31557609]
NPT927 Cell Line PBMC Homo sapiens CC50 > 100000.0 nM PMID[27390064]
NPT404 Cell Line CCRF-CEM Homo sapiens CC50 > 100000.0 nM PMID[27390064]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 100000.0 nM PMID[27390064]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 160.0 nM PMID[27390064]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 100.0 nM PMID[27339173]
NPT109 Individual Protein Cytochrome P450 3A4 Homo sapiens FC = 1.0 n.a. PMID[27397500]
NPT110 Individual Protein Cytochrome P450 2D6 Homo sapiens FC = 1.0 n.a. PMID[27397500]
NPT212 Individual Protein Cytochrome P450 2C9 Homo sapiens FC = 1.0 n.a. PMID[27397500]
NPT460 Cell Line MT2 Homo sapiens CC50 > 100000.0 nM PMID[27485603]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 8780.0 nM PMID[27501911]
NPT25 Cell Line MT4 Homo sapiens CC50 >= 15020.0 nM PMID[27501911]
NPT993 Cell Line Hepatocyte Mus musculus Activity = 52.6 % PMID[32065749]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 570.0 nM PMID[32435389]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1550.0 nM PMID[32197813]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[32197813]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 1060.0 nM PMID[33603971]
NPT460 Cell Line MT2 Homo sapiens CC50 > 100000.0 nM PMID[33603971]
NPT25 Cell Line MT4 Homo sapiens CC50 > 4600.0 nM PMID[31767136]
NPT25 Cell Line MT4 Homo sapiens CC50 > 9510.0 nM PMID[32200201]
NPT25 Cell Line MT4 Homo sapiens CC50 > 18776.0 nM PMID[32883642]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 400.0 nM PMID[32883642]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 7000.0 nM PMID[32883642]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[33279288]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 640.0 nM PMID[33279288]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 645.65 nM PMID[33279288]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[33567378]
NPT26 Individual Protein Reverse transcriptase Human immunodeficiency virus 1 EC50 = 622.0 nM PMID[33567378]
NPT26 Individual Protein Reverse transcriptase Human immunodeficiency virus 1 EC50 = 3922.0 nM PMID[33567378]
NPT26 Individual Protein Reverse transcriptase Human immunodeficiency virus 1 EC50 = 9074.0 nM PMID[33567378]
NPT26 Individual Protein Reverse transcriptase Human immunodeficiency virus 1 EC50 = 168.0 nM PMID[33567378]
NPT26 Individual Protein Reverse transcriptase Human immunodeficiency virus 1 EC50 = 8041.0 nM PMID[33567378]
NPT459 Individual Protein Human immunodeficiency virus type 1 reverse transcriptase Human immunodeficiency virus 1 IC50 = 575.0 nM PMID[33567378]
NPT460 Cell Line MT2 Homo sapiens CC50 = 96171.0 nM PMID[31893549]
NPT2615 Cell Line HEK-293T Homo sapiens CC50 = 23720.0 nM PMID[32004936]
NPT2615 Cell Line HEK-293T Homo sapiens Activity = 93.26 % PMID[32004936]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15020.0 nM PMID[32712537]
NPT26 Individual Protein Reverse transcriptase Human immunodeficiency virus 1 EC50 = 1201.7 nM PMID[32712537]
NPT26 Individual Protein Reverse transcriptase Human immunodeficiency virus 1 EC50 = 3154.3 nM PMID[32712537]
NPT26 Individual Protein Reverse transcriptase Human immunodeficiency virus 1 EC50 = 6496.4 nM PMID[32712537]
NPT26 Individual Protein Reverse transcriptase Human immunodeficiency virus 1 EC50 = 4694.0 nM PMID[32712537]
NPT26 Individual Protein Reverse transcriptase Human immunodeficiency virus 1 EC50 = 2441000.0 nM PMID[32712537]
NPT25 Cell Line MT4 Homo sapiens CC50 > 15000.0 nM PMID[32977301]
NPT27 Others Unspecified IC50 = 34.0 nM PMID[10386942]
NPT27 Others Unspecified IC50 = 5000.0 nM PMID[10386942]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[10386942]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 100.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 6600.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 9000.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 150.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 290.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 520.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 500.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 10000.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 1200.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 56.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 9400.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 2300.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 65.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 9800.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 8000.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 15000.0 nM PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 1.0 n.a. PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 2.5 n.a. PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 2.0 n.a. PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 0.8 n.a. PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 1.2 n.a. PMID[14971897]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 40.0 nM DOI[10.1016/S0960-894X(00)80447-3]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC90 = 37.0 nM PMID[10673109]
NPT18340 SINGLE PROTEIN Human immunodeficiency virus type 2 pol protein Human immunodeficiency virus 2 IC50 > 20000.0 nM PMID[8558522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 = 50.0 nM PMID[10821714]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 = 5100.0 nM PMID[10821714]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 = 10200.0 nM PMID[10821714]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 400.0 nM PMID[15239667]
NPT2 Others Unspecified Ratio > 270.0 n.a. PMID[15239667]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 30000.0 nM PMID[15239667]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC90 > 30.0 uM PMID[15239667]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 300.0 nM PMID[11472208]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 250.0 nM DOI[10.1016/S0960-894X(97)00340-5]
NPT2 Others Unspecified Ratio > 800.0 n.a. DOI[10.1016/S0960-894X(97)00340-5]
NPT2 Others Unspecified Ratio > 81.0 n.a. PMID[14761194]
NPT27 Others Unspecified IC50 = 34.0 nM PMID[10999473]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 100000.0 nM PMID[10999473]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 0.01 ug.mL-1 PMID[7538590]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 0.38 uM PMID[12477355]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 > 100.0 uM PMID[12477355]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 0.57 uM PMID[12477355]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 22.0 uM PMID[12477355]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 4.3 uM PMID[12477355]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. ED50 = 0.01 uM PMID[10715167]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. CC50 > 10000.0 nM PMID[10715167]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 85.0 nM PMID[15115397]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 638.0 nM PMID[15115397]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2467.0 nM PMID[15115397]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2410.0 nM PMID[15115397]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5351.0 nM PMID[15115397]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 100000.0 nM PMID[15115397]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3465.0 nM PMID[15115397]
NPT2 Others Unspecified CC50 > 300000.0 nM PMID[10698447]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 34.0 nM PMID[11229762]
NPT27 Others Unspecified IC50 = 34.0 nM PMID[10509923]
NPT27 Others Unspecified IC50 = 5000.0 nM PMID[10509923]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[10509923]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. CC50 = 10500.0 nM PMID[10509923]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 0.01 uM PMID[7684450]
NPT27 Others Unspecified CC50 > 10000.0 nM PMID[7684450]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 32.0 nM PMID[11527705]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 316.0 nM PMID[11527705]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 6310.0 nM PMID[11527705]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 10000.0 nM PMID[11527705]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 100000.0 nM PMID[11527705]
NPT27 Others Unspecified IC50 = 34.0 nM PMID[10617082]
NPT27 Others Unspecified IC50 = 5000.0 nM PMID[10617082]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[10617082]
NPT27 Others Unspecified CC50 = 10500.0 nM PMID[10617082]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 0.15 uM PMID[9873380]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 0.12 uM PMID[9873380]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 0.62 uM PMID[9873380]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 22.0 uM PMID[9873380]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.038 ug.mL-1 PMID[1495006]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 39.8 nM PMID[15771449]
NPT27 Others Unspecified CC50 = 20000.0 nM PMID[15771449]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6310.0 nM PMID[15771449]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 10000.0 nM PMID[15771449]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10.0 nM PMID[15771449]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 316.0 nM PMID[15771449]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[15771449]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 32.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 195.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 7943.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 440.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 135.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 1452.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 509.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 100000.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 163.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 6310.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 10000.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 316.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 5012.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 50.0 nM PMID[15771439]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 81.0 nM PMID[15771434]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 597.0 nM PMID[15771434]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2879.0 nM PMID[15771434]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 10000.0 nM PMID[15771434]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1000.0 nM PMID[15771434]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 30.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 190.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 7940.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 40.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 130.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 1450.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 500.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 20.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 6310.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 10000.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 100000.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 310.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 5010.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 50.0 nM PMID[15481987]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 89.0 nM PMID[15537347]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 200.0 nM PMID[15801834]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 52.0 nM PMID[16335924]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 7500.0 nM PMID[16335924]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3900.0 nM PMID[16335924]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 5800.0 nM PMID[16420058]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 8200.0 nM PMID[16420058]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 10300.0 nM PMID[16420058]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 120.0 nM PMID[16263277]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 120.0 nM PMID[16298131]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 50.0 nM PMID[16480865]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 50.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 164.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5053.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 8458.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 207.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 79.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 31.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 116.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 733.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 148.0 nM PMID[16464578]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 370.0 nM PMID[16722636]
NPT20910 CELL-LINE Lymphocytes n.a. TC50 > 100.0 uM PMID[16722636]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 90.0 nM PMID[16722636]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus EC50 > 20000.0 nM PMID[16722636]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 4386.0 nM PMID[16632349]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 164.0 nM PMID[16632349]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[16632349]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5053.0 nM PMID[16632349]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 50.0 nM PMID[16632349]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 10000.0 nM PMID[16781149]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3001.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 112.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 116.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 8458.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 164.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5053.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 79.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 148.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 31.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 50.0 nM PMID[16782337]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 164.0 nM PMID[16781149]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5053.0 nM PMID[16781149]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[16781149]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 50.0 nM PMID[16781149]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[16931015]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 250.0 nM PMID[17381078]
NPT2 Others Unspecified Ratio CC50/IC50 > 800.0 n.a. PMID[17381078]
NPT2 Others Unspecified Activity = 256.0 uM PMID[17116672]
NPT2 Others Unspecified IC50 = 400.0 nM PMID[16279773]
NPT2 Others Unspecified IC50 = 100000.0 nM PMID[17458947]
NPT2 Others Unspecified IC50 = 77200.0 nM PMID[17458947]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 35.0 nM PMID[17663538]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 100.0 nM PMID[17663538]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 720.0 nM PMID[17663538]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1100.0 nM PMID[17663538]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1090.0 nM PMID[17663538]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 200.0 nM PMID[17663538]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 4900.0 nM PMID[17663538]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2360.0 nM PMID[17663538]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 33.3 nM PMID[17223230]
NPT2 Others Unspecified Ratio CC50/EC50 > 949.0 n.a. PMID[17223230]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 209.0 nM PMID[17223230]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5910.0 nM PMID[17223230]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1980.0 nM PMID[17223230]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 7078.0 nM PMID[17223230]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 827.0 nM PMID[17223230]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3532.0 nM PMID[17223230]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 14505.0 nM PMID[17223230]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2697.0 nM PMID[17223230]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 50.0 nM PMID[17803291]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 14000.0 nM PMID[17803291]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 > 20000.0 nM PMID[17803291]
NPT27 Others Unspecified TC50 > 20000.0 nM PMID[17803291]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 90.0 nM PMID[17803291]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 15.0 nM PMID[17803290]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 53.0 nM PMID[17803290]
NPT2 Others Unspecified Ratio CC50/EC50 = 417.0 n.a. PMID[17321639]
NPT3795 Organism Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 > 50000.0 nM PMID[17321639]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 120.0 nM PMID[17321639]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 73.0 nM PMID[17276064]
NPT2 Others Unspecified Ratio CC50/EC50 > 205.0 n.a. PMID[17276064]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 30.0 nM PMID[17276064]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 199.0 nM PMID[17276064]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1300.0 nM PMID[17276064]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 207.0 nM PMID[17276064]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2500.0 nM PMID[17276064]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 75000.0 nM PMID[17276064]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 80.0 nM PMID[17910429]
NPT2 Others Unspecified Ratio CC50/EC50 > 87.0 n.a. PMID[17910429]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 9900.0 nM PMID[17910429]
NPT2 Others Unspecified Ratio EC50 = 124.0 n.a. PMID[17910429]
NPT2 Others Unspecified Ratio EC50 = 23.0 n.a. PMID[17910429]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1800.0 nM PMID[17910429]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 870.0 nM PMID[17910429]
NPT2 Others Unspecified Ratio EC50 = 11.0 n.a. PMID[17910429]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5600.0 nM PMID[17910429]
NPT2 Others Unspecified Ratio EC50 = 70.0 n.a. PMID[17910429]
NPT2 Others Unspecified Ratio Ki = 17.0 n.a. PMID[17910429]
NPT2 Others Unspecified Ki = 35000.0 nM PMID[17910429]
NPT2 Others Unspecified Ratio Ki = 22.0 n.a. PMID[17910429]
NPT2 Others Unspecified Ratio Ki = 25.0 n.a. PMID[17910429]
NPT2 Others Unspecified Ratio Ki = 0.8 n.a. PMID[17910429]
NPT2 Others Unspecified Ratio Ki = 87.0 n.a. PMID[17910429]
NPT2 Others Unspecified Ratio Ki = 45.0 n.a. PMID[17910429]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[17918923]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus EC50 = 50.0 nM PMID[17035019]
NPT27 Others Unspecified CC50 > 10000.0 nM PMID[17035019]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1.5 nM PMID[18083556]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 53.0 nM PMID[18083556]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1.5 nM PMID[18222088]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 53.0 nM PMID[18222088]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 30.0 nM PMID[17964796]
NPT2 Others Unspecified Ratio CC50/EC50 = 22767.0 n.a. PMID[17964796]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 250.0 nM PMID[17869386]
NPT2 Others Unspecified Ratio CC50/IC50 > 800.0 n.a. PMID[17869386]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 294.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 53.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 2000.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 1868.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 304.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 83.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 89.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 409.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 118.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 59.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 801.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 71.0 nM PMID[18665583]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 0.04 uM PMID[18842407]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 = 0.68 uM PMID[18842407]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 > 2.0 uM PMID[18842407]
NPT2 Others Unspecified Ratio EC50 = 17.0 n.a. PMID[18842407]
NPT2 Others Unspecified Ratio CC50/EC50 = 417.0 n.a. PMID[18420310]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 120.0 nM PMID[18420310]
NPT3795 Organism Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 > 50000.0 nM PMID[18420310]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[17470654]
NPT6406 Organism Porcine endogenous retrovirus Porcine endogenous retrovirus EC50 > 100000.0 nM PMID[17470654]
NPT2 Others Unspecified Activity = 47.5 % PMID[18800765]
NPT2 Others Unspecified Ratio = 0.6 n.a. PMID[18800765]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 14.0 nM PMID[18800765]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 10.0 nM PMID[18800765]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 24.0 nM PMID[18800765]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 50.0 nM PMID[18800765]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 40.0 nM PMID[18800765]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus EC50 > 4.0 ug.mL-1 PMID[19091580]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus EC50 = 0.023 ug.mL-1 PMID[19091580]
NPT2 Others Unspecified Ratio CC50/EC50 > 176.0 n.a. PMID[19091580]
NPT2 Others Unspecified Ki = 2000.0 nM PMID[19170521]
NPT2 Others Unspecified Ki = 10000.0 nM PMID[19170521]
NPT2 Others Unspecified Ki = 18000.0 nM PMID[19170521]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 60.0 nM PMID[19281225]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 2900.0 nM PMID[19281225]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 11000.0 nM PMID[19281225]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 10000.0 nM PMID[19281225]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 208.0 nM PMID[18824350]
NPT2 Others Unspecified Ratio CC50/EC50 > 72.0 n.a. PMID[18824350]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 80.0 nM PMID[19140683]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3900.0 nM PMID[19140683]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 7500.0 nM PMID[19140683]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 250.0 nM PMID[18952324]
NPT27 Others Unspecified Ratio CC50/EC50 > 800.0 n.a. PMID[18952324]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 130.0 nM PMID[18630898]
NPT2 Others Unspecified Ratio CC50/EC50 > 54.0 n.a. PMID[18630898]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 4960.0 nM PMID[18630898]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 7000.0 nM PMID[18630898]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 38.0 n.a. PMID[18630898]
NPT2 Others Unspecified Ratio = 22.0 n.a. PMID[18630898]
NPT2 Others Unspecified Ratio = 87.0 n.a. PMID[18630898]
NPT2 Others Unspecified Ratio = 17.0 n.a. PMID[18630898]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 73.0 nM PMID[18585918]
NPT2 Others Unspecified Ratio CC50/EC50 > 205.0 n.a. PMID[18585918]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 14800.0 nM PMID[19053755]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 290.0 nM PMID[19053755]
NPT2 Others Unspecified Ratio EC50 > 51.21 n.a. PMID[19053755]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 60.0 nM PMID[19112024]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 50.0 nM PMID[18242784]
NPT2 Others Unspecified Ratio CC50/EC50 > 1000.0 n.a. PMID[18242784]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 10.0 nM PMID[18242784]
NPT2 Others Unspecified Ratio CC50/EC50 > 370.0 n.a. PMID[18242784]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[19469474]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6200.0 nM PMID[19469474]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 792.0 nM PMID[19469474]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 252.0 nM PMID[19469474]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3300.0 nM PMID[19469474]
NPT2 Others Unspecified Ratio CC50/EC50 = 2564.0 n.a. PMID[19469474]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 39.0 nM PMID[19469474]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition = 50.0 % PMID[17724147]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition < 50.0 % PMID[17724147]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 73.0 nM PMID[19616956]
NPT2 Others Unspecified Ratio CC50/EC50 > 205.0 n.a. PMID[19616956]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 208.0 nM PMID[19643613]
NPT2 Others Unspecified Ratio CC50/EC50 > 72.0 n.a. PMID[19643613]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 600.0 nM PMID[19775161]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 800.0 nM PMID[19775161]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 300.0 nM PMID[19775780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 7000.0 nM PMID[19775780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 20000.0 nM PMID[19775780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 1452.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 135.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 44.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 7943.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 195.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 51.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 5012.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 316.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 100000.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 10000.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 6310.0 nM PMID[19645483]
NPT2 Others Unspecified Ratio CC50/IC50 = 5012.0 n.a. PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 31.6 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 509.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 163.0 nM PMID[19645483]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 8.2 nM PMID[20050672]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 97.5 nM PMID[20050672]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 13416.0 nM PMID[20050672]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 42.6 nM PMID[20050672]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 10475.0 nM PMID[20050672]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 385.0 nM PMID[20050672]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6151.0 nM PMID[20050672]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 208.0 nM PMID[19628308]
NPT2 Others Unspecified Ratio CC50/EC50 > 72.0 n.a. PMID[19628308]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 73.0 nM PMID[20097079]
NPT2 Others Unspecified Ratio CC50/EC50 > 205.0 n.a. PMID[20097079]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[20304641]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 200.0 nM PMID[20307984]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15020.0 nM PMID[20307984]
NPT2 Others Unspecified Ratio CC50/EC50 > 75.0 n.a. PMID[20307984]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.008 ug.mL-1 PMID[20377249]
NPT3795 Organism Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 > 2.0 ug.mL-1 PMID[20377249]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus EC50 = 0.005 ug.mL-1 PMID[20377249]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus EC50 < 0.2 ug.mL-1 PMID[20377249]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus EC50 = 0.016 ug.mL-1 PMID[20377249]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus EC50 = 0.012 ug.mL-1 PMID[20377249]
NPT27 Others Unspecified CC50 > 2.0 ug.mL-1 PMID[20377249]
NPT2 Others Unspecified Ratio CC50/EC50 < 250.0 n.a. PMID[20377249]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 75.0 nM PMID[20570527]
NPT2 Others Unspecified Ratio CC50/EC50 > 200.0 n.a. PMID[20570527]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15020.0 nM PMID[20570527]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1316.0 nM PMID[20598556]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 15000.0 nM PMID[20598556]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 53.0 nM PMID[20527972]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 3700.0 nM PMID[20527972]
NPT2 Others Unspecified Ratio CC50/EC50 > 114.0 n.a. PMID[20598556]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 102.0 nM PMID[20598556]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 162.0 nM PMID[20598556]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2030.0 nM PMID[20598556]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6729.0 nM PMID[20598556]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15037.0 nM PMID[20598556]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.9 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 2.0 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 1.4 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 1.3 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 1.1 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.7 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 8.3 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 2.2 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.6 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 4.4 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 2.5 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.8 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 2.9 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.5 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.4 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 > 49.6 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 > 70.9 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 2.4 n.a. PMID[20008779]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 30.0 nM PMID[20638854]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) IC50 = 15000.0 nM PMID[20638854]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 34.09 nM PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 9.32 nM PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 8.94 nM PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 14.4 nM PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 25.99 nM PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 < 4.88 nM PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 24.17 nM PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 14.88 nM PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 24.63 nM PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 34.14 nM PMID[19933797]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 31250.0 nM PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 3.8 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 2.9 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 2.0 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 4.4 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 7.3 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 166.1 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 2.5 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 42.1 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 59.4 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 49.0 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 6.3 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 3.1 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 2.3 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 2.8 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 1.1 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 5.1 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 4.6 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 2.1 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 0.6 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 0.8 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 43.0 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 65.7 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 2155.9 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 86.6 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 96.9 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 4.3 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 13.6 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 20.4 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 1.4 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 3.4 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 18.1 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 42.5 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 41.6 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 141.1 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 205.2 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 41.8 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 71.5 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 63.7 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 358.3 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 139.9 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 77.3 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 157.7 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 58.1 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 51.6 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 468.1 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 429.9 n.a. PMID[19933797]
NPT2 Others Unspecified Ratio CC50/EC50 = 8000.0 n.a. PMID[19933797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 460.0 nM PMID[18378713]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 380.0 nM PMID[18378713]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 350.0 nM PMID[18378713]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 310.0 nM PMID[18378713]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 170.0 nM PMID[18378713]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[18378713]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 150.0 nM PMID[18378713]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 8.4 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 9.2 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 4.1 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 58.6 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 81.0 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC > 400.0 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 317.0 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 127.7 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 145.0 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 2.1 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 5.3 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 4.8 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 56.3 n.a. PMID[20194692]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 50.0 nM PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3430.0 nM PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 20.0 nM PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 130.0 nM PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 4530.0 nM PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 370.0 nM PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 69.0 n.a. PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 0.4 n.a. PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 2.6 n.a. PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 91.0 n.a. PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 7.0 n.a. PMID[20124001]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 163.0 nM PMID[20308384]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2690.0 nM PMID[20308384]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 1000.0 nM PMID[20888224]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 200.0 nM PMID[20888224]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 CC50 > 749100.0 nM PMID[21194939]
NPT27 Others Unspecified EC50 = 49.43 nM PMID[21194939]
NPT2 Others Unspecified Ratio CC50/IC50 > 15154.0 n.a. PMID[21194939]
NPT27 Others Unspecified Ratio = 0.59 n.a. PMID[19307360]
NPT27 Others Unspecified Ratio = 0.53 n.a. PMID[19307360]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 1.3 n.a. PMID[19223644]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 1.1 n.a. PMID[19223644]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.7 n.a. PMID[19223644]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.5 n.a. PMID[19223644]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.13 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.32 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.35 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.4 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.49 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.67 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.7 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.73 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.83 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.94 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 1.05 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 1.25 n.a. PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 = 438.0 nM PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 = 464.0 nM PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 > 8000.0 nM PMID[19289522]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 130.0 nM PMID[21093117]
NPT1118 Organism Streptococcus pneumoniae Streptococcus pneumoniae MIC = 4.0 ug.mL-1 PMID[19487448]
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC = 4.0 ug.mL-1 PMID[19487448]
NPT19 Organism Escherichia coli Escherichia coli MIC = 4.0 ug.mL-1 PMID[19487448]
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 4.0 ug.mL-1 PMID[19487448]
NPT1243 Organism Shigella sonnei Shigella sonnei MIC = 4.0 ug.mL-1 PMID[19487448]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 4.0 ug.mL-1 PMID[19487448]
NPT1246 Organism Salmonella Salmonella MIC = 4.0 ug.mL-1 PMID[19487448]
NPT2909 Organism Shigella flexneri Shigella flexneri MIC = 4.0 ug.mL-1 PMID[19487448]
NPT2 Others Unspecified IC50 > 1000000.0 nM PMID[19704127]
NPT2 Others Unspecified IC50 > 67000.0 nM PMID[19704127]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.007 nM PMID[19704127]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.01 nM PMID[19704127]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.02 nM PMID[19704127]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.852 nM PMID[19704127]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.703 nM PMID[19704127]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.997 nM PMID[19704127]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 71.0 n.a. PMID[19704127]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 58.0 n.a. PMID[19704127]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 83.0 n.a. PMID[19704127]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.8 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.7 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.4 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 1.3 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 1.2 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 1.4 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 7.0 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 3.4 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 5.0 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 1.7 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 1.0 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 2.4 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 3.8 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.6 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.9 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 0.5 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 3.1 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 2.1 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 1.1 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 89.0 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 222.0 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 22.0 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 96.0 n.a. PMID[19029331]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 41.0 nM PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 = 0.69 uM PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 27.0 nM PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 = 0.64 uM PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 100000.0 nM PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 2439.0 n.a. PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 3703.0 n.a. PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity = 0.36 % PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity = 23.0 % PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 1370.0 n.a. PMID[21060108]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 73.0 nM PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 = 0.68 uM PMID[21060108]
NPT2 Others Unspecified Ratio CC50/EC50 > 1369.0 n.a. PMID[21060108]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 1.0 n.a. PMID[20660667]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 6.4 n.a. PMID[20660667]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 12.2 n.a. PMID[20660667]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.9 n.a. PMID[20660667]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 0.2 n.a. PMID[20660667]
NPT2 Others Unspecified IC50 > 0.2663 ug.mL-1 PMID[21334901]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 0.09 ug.mL-1 PMID[21334901]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition = 100.0 % PMID[21334901]
NPT27 Others Unspecified CC50 = 20.06 ug.mL-1 PMID[21334901]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 40.0 nM PMID[21414776]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 10000.0 nM PMID[21366296]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 19.2 nM PMID[21366296]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 210.0 nM PMID[21683601]
NPT2 Others Unspecified Ratio CC50/EC50 > 72.0 n.a. PMID[21683601]
NPT27 Others Unspecified CC50 > 10000.0 nM PMID[21700466]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 90.0 nM PMID[21700466]
NPT2 Others Unspecified Ratio CC50/IC50 > 111.0 n.a. PMID[21700466]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 180.0 nM PMID[21824782]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 9500.0 nM PMID[21824782]
NPT2 Others Unspecified Ratio CC50/EC50 > 83.0 n.a. PMID[21824782]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 190.0 nM PMID[21872971]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 15000.0 nM PMID[21872971]
NPT2 Others Unspecified Ratio CC50/EC50 > 80.0 n.a. PMID[21872971]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 180.0 nM PMID[21872971]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 7250.0 nM PMID[21872971]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1920.0 nM PMID[21872971]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 48.25 n.a. PMID[21872971]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 1.2 n.a. PMID[21872971]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 12.75 n.a. PMID[21872971]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 75.0 nM PMID[21903401]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[21903401]
NPT2 Others Unspecified Ki = 4200.0 nM PMID[21903401]
NPT2 Others Unspecified Ratio CC50/EC50 > 200.0 n.a. PMID[21903401]
NPT2 Others Unspecified Ratio CC50/EC50 = 1.0 n.a. PMID[21903401]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 200.0 n.a. PMID[21903401]
NPT2 Others Unspecified Ki = 61000.0 nM PMID[21903401]
NPT2 Others Unspecified Ki = 482000.0 nM PMID[21903401]
NPT2 Others Unspecified Ki > 1000000.0 nM PMID[21903401]
NPT2 Others Unspecified Ki = 1362000.0 nM PMID[21903401]
NPT2 Others Unspecified Ratio Ki = 15.0 n.a. PMID[21903401]
NPT2 Others Unspecified Ratio Ki = 400.0 n.a. PMID[21903401]
NPT2 Others Unspecified Ratio Ki = 395.0 n.a. PMID[21903401]
NPT2 Others Unspecified Ratio Ki > 250.0 n.a. PMID[21903401]
NPT2 Others Unspecified Ratio Ki = 423.0 n.a. PMID[21903401]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.05 ug.mL-1 PMID[21982685]
NPT27 Others Unspecified CC50 = 76.13 ug.mL-1 PMID[21982685]
NPT2 Others Unspecified Ratio CC50/EC50 = 1522.2 n.a. PMID[21982685]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[22081993]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 100000.0 nM PMID[22081993]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 81.0 nM PMID[22081993]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[22081993]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 210.0 nM PMID[22037050]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3490.0 nM PMID[22037050]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 15020.0 nM PMID[22037050]
NPT2 Others Unspecified Ratio CC50/EC50 > 72.0 n.a. PMID[22037050]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 150.0 nM PMID[22305583]
NPT27 Others Unspecified CC50 > 10000.0 nM PMID[22305583]
NPT2 Others Unspecified Ratio CC50/EC50 = 57.15 n.a. PMID[21438533]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 47.0 n.a. PMID[21438533]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 7510.0 nM PMID[21438533]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6121.0 nM PMID[21438533]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 83.0 n.a. PMID[21438533]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 18850.0 nM PMID[21438533]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 131.4 nM PMID[21438533]
NPT2 Others Unspecified Ratio = 45.0 n.a. PMID[21438533]
NPT2 Others Unspecified Ratio = 87.0 n.a. PMID[21438533]
NPT2 Others Unspecified Ratio = 17.0 n.a. PMID[21438533]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 90.1 nM PMID[22405288]
NPT2 Others Unspecified Ratio CC50/EC50 > 168.0 n.a. PMID[22405288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 11200.0 nM PMID[22405288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 150.0 nM PMID[22374216]
NPT27 Others Unspecified CC50 > 10000.0 nM PMID[22374216]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 130.0 nM PMID[22428851]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6100.0 nM PMID[22428851]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 7500.0 nM PMID[22428851]
NPT2 Others Unspecified Ratio CC50/EC50 = 58.0 n.a. PMID[22428851]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 47.0 n.a. PMID[22428851]
NPT2 Others Unspecified Ratio = 20.0 n.a. PMID[22428851]
NPT2 Others Unspecified Ratio = 87.0 n.a. PMID[22428851]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 210.0 nM PMID[22575532]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3500.0 nM PMID[22575532]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 15000.0 nM PMID[22575532]
NPT2 Others Unspecified Ratio CC50/EC50 > 72.0 n.a. PMID[22575532]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 75.0 n.a. PMID[22591854]
NPT2 Others Unspecified Ratio CC50/EC50 >= 1.0 n.a. PMID[22591854]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15020.0 nM PMID[22591854]
NPT2 Others Unspecified Ratio CC50/EC50 > 75.0 n.a. PMID[22591854]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 200.4 nM PMID[22591854]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[22652226]
NPT2 Others Unspecified Ratio CC50/EC50 > 167.0 n.a. PMID[22652226]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[22283377]
NPT2 Others Unspecified Ratio CC50/EC50 = 4781.0 n.a. PMID[22283377]
NPT2 Others Unspecified Ratio CC50/EC50 < 35.0 n.a. PMID[22283377]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 68.0 nM PMID[22283377]
NPT2 Others Unspecified Inhibition = 97.91 % PMID[22871486]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 87.0 nM PMID[24900496]
NPT433 Subcellular Liver microsomes Homo sapiens Activity = 19.0 pmol PMID[22931300]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 200.0 nM PMID[22883027]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[22883027]
NPT2 Others Unspecified Ratio CC50/EC50 > 75.0 n.a. PMID[22883027]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 150.0 nM PMID[24900529]
NPT27 Others Unspecified CC50 > 10000.0 nM PMID[24900529]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 97.0 nM PMID[23159806]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 7600.0 nM PMID[23159806]
NPT2 Others Unspecified Ratio CC50/EC50 > 155.0 n.a. PMID[23159806]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1502.0 nM PMID[22712652]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 3756.0 nM PMID[22712652]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 2.5 n.a. PMID[22712652]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 18916.0 nM PMID[22712652]
NPT2 Others Unspecified Ratio CC50/EC50 > 13.0 n.a. PMID[22712652]
NPT2 Others Unspecified Ratio CC50/EC50 > 1.0 n.a. PMID[23084898]
NPT2 Others Unspecified Ratio CC50/EC50 = 75.0 n.a. PMID[23084898]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 11000.0 nM PMID[23084898]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 90.0 nM PMID[23084898]
NPT2 Others Unspecified Ratio CC50/EC50 > 168.0 n.a. PMID[23098609]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 90.0 nM PMID[23098609]
NPT3795 Organism Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 > 4.0 ug.mL-1 DOI[10.1007/s00044-011-9662-9]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.05 ug.mL-1 DOI[10.1007/s00044-011-9662-9]
NPT2 Others Unspecified Ratio CC50/EC50 > 72.0 n.a. DOI[10.1007/s00044-009-9220-x]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 208.0 nM DOI[10.1007/s00044-009-9220-x]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 = 4.0 ug.mL-1 DOI[10.1007/s00044-011-9664-7]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.05 ug.mL-1 DOI[10.1007/s00044-011-9664-7]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 4.0 ug.mL-1 DOI[10.1007/s00044-011-9705-2]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.05 ug.mL-1 DOI[10.1007/s00044-011-9705-2]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 4.0 ug.mL-1 DOI[10.1007/s00044-011-9776-0]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.05 ug.mL-1 DOI[10.1007/s00044-011-9776-0]
NPT2 Others Unspecified Ratio CC50/IC50 < 1.0 n.a. DOI[10.1007/s00044-013-0567-7]
NPT2 Others Unspecified Ratio CC50/IC50 > 80.0 n.a. DOI[10.1007/s00044-013-0567-7]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) IC50 > 4.0 ug.mL-1 DOI[10.1007/s00044-013-0567-7]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 0.05 ug.mL-1 DOI[10.1007/s00044-013-0567-7]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus Activity = 98.0 % DOI[10.1007/s00044-012-0143-6]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus IC50 = 100.0 nM DOI[10.1007/s00044-012-0143-6]
NPT2 Others Unspecified Ratio CC50/IC50 > 80.0 n.a. DOI[10.1007/s00044-012-0129-4]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 0.05 ug.mL-1 DOI[10.1007/s00044-012-0129-4]
NPT27 Others Unspecified CC50 > 10000.0 nM PMID[23206860]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 150.0 nM PMID[23206860]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[23298809]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[23540737]
NPT2 Others Unspecified Ratio CC50/EC50 < 32.0 n.a. PMID[23540737]
NPT2 Others Unspecified Ratio CC50/EC50 < 20.0 n.a. PMID[23540737]
NPT2 Others Unspecified Ratio CC50/EC50 = 4781.0 n.a. PMID[23540737]
NPT2 Others Unspecified Ratio CC50/EC50 = 1073.0 n.a. PMID[23540737]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 68.0 nM PMID[23540737]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 190.0 nM PMID[23540737]
NPT27 Others Unspecified CC50 = 204003.0 nM PMID[23540737]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus Ratio EC50 > 100.0 n.a. PMID[23375792]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus EC50 > 10000.0 nM PMID[23375792]
NPT1114 Organism Human immunodeficiency virus Human immunodeficiency virus EC50 = 74.0 nM PMID[23375792]
NPT2 Others Unspecified IC50 = 309.0 nM PMID[23375792]
NPT2 Others Unspecified Ki > 2000000.0 nM PMID[23357038]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 48.0 nM PMID[23357038]
NPT2 Others Unspecified Ratio CC50/EC50 > 400.0 n.a. PMID[23357038]
NPT2 Others Unspecified Ratio CC50/EC50 > 75.0 n.a. PMID[23415090]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 199.0 nM PMID[23415090]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 15020.0 nM PMID[23707918]
NPT2 Others Unspecified Ratio CC50/EC50 > 132.0 n.a. PMID[23707918]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5120.0 nM PMID[23707918]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[23707918]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[23937980]
NPT2 Others Unspecified Ratio CC50/EC50 > 1639.0 n.a. PMID[23916148]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[23899617]
NPT2 Others Unspecified Ratio CC50/EC50 > 133.0 n.a. PMID[24119448]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[24119448]
NPT2 Others Unspecified Ratio CC50/EC50 = 179.4 n.a. PMID[24055077]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1970.0 nM PMID[24055077]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 84.0 nM PMID[24055077]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2500.0 nM PMID[24239481]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 170.0 nM PMID[24239481]
NPT2 Others Unspecified Ratio CC50/EC50 > 133.0 n.a. PMID[24134904]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 5000.0 nM PMID[24134904]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 113.0 nM PMID[24134904]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 23.0 nM PMID[24308675]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 1013.0 n.a. PMID[24308675]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 2256.0 n.a. PMID[24308675]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 317.4 n.a. PMID[24308675]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 140.0 n.a. PMID[24308675]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 99.1 n.a. PMID[24308675]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 23300.0 nM PMID[24308675]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 51900.0 nM PMID[24308675]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 7500.0 nM PMID[24308675]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3300.0 nM PMID[24308675]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2300.0 nM PMID[24308675]
NPT2 Others Unspecified Ratio CC50/EC50 > 89.0 n.a. PMID[24239481]
NPT2 Others Unspecified Ratio CC50/EC50 > 6.0 n.a. PMID[24239481]
NPT2 Others Unspecified Ratio CC50/EC50 > 79.0 n.a. PMID[24457088]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 190.0 nM PMID[24457088]
NPT2 Others Unspecified Ratio CC50/EC50 > 4.0 n.a. PMID[24581546]
NPT2 Others Unspecified Ratio CC50/EC50 > 83.0 n.a. PMID[24581546]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3500.0 nM PMID[24581546]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 180.0 nM PMID[24581546]
NPT2 Others Unspecified Ratio CC50/EC50 > 4.0 n.a. PMID[24602795]
NPT2 Others Unspecified Ratio CC50/EC50 > 67.0 n.a. PMID[24602795]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 4090.0 nM PMID[24602795]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 230.0 nM PMID[24602795]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 > 250.0 n.a. DOI[10.1039/C3MD00337J]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 32.0 n.a. DOI[10.1039/C3MD00337J]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 10000.0 nM DOI[10.1039/C3MD00337J]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 1290.0 nM DOI[10.1039/C3MD00337J]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 40.0 nM DOI[10.1039/C3MD00337J]
NPT2 Others Unspecified Ratio CC50/EC50 > 132.0 n.a. DOI[10.1039/C3MD00247K]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5120.0 nM DOI[10.1039/C3MD00247K]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM DOI[10.1039/C3MD00247K]
NPT27 Others Unspecified Ratio CC50/EC50 > 168.0 n.a. DOI[10.1039/C3MD00028A]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 90.0 nM DOI[10.1039/C3MD00028A]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 24.0 nM DOI[10.1039/C3MD00036B]
NPT2 Others Unspecified IC50 > 2000000.0 nM DOI[10.1039/C3MD00225J]
NPT2 Others Unspecified Inhibition < 10.0 % DOI[10.1039/C3MD00225J]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 170.0 nM PMID[24631361]
NPT2 Others Unspecified Ratio CC50/EC50 > 89.0 n.a. PMID[24631361]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 101.0 nM PMID[24680058]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 901.0 nM PMID[24680058]
NPT2 Others Unspecified Ratio CC50/IC50 > 148.0 n.a. PMID[24680058]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 112.4 nM PMID[24769348]
NPT2 Others Unspecified Ratio CC50/EC50 > 167.0 n.a. PMID[24769348]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 19.2 nM PMID[24769348]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 10000.0 nM PMID[24769348]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 3756.0 nM PMID[24769348]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 33.0 n.a. PMID[24769348]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 60.0 nM PMID[24769348]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 1.8 n.a. PMID[24769348]
NPT2 Others Unspecified IC50 > 20000.0 nM PMID[24769348]
NPT2 Others Unspecified Ratio CC50/EC50 > 62.0 n.a. PMID[24933420]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5600.0 nM PMID[24933420]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 7000.0 nM PMID[24933420]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 47.0 n.a. PMID[24933420]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 30.0 nM PMID[24794742]
NPT2 Others Unspecified Ratio = 17.0 n.a. PMID[24933420]
NPT2 Others Unspecified Ratio = 87.0 n.a. PMID[24933420]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 101.0 nM PMID[24952305]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 900.0 nM PMID[24952305]
NPT2 Others Unspecified Ratio CC50/IC50 > 148.0 n.a. PMID[24952305]
NPT27 Others Unspecified CC50 = 76130.0 nM PMID[24794742]
NPT2 Others Unspecified Ratio CC50/EC50 = 2057.0 n.a. PMID[24794742]
NPT2 Others Unspecified Inhibition = 99.2 % PMID[24794742]
NPT2 Others Unspecified Ratio = 22.0 n.a. PMID[24933420]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 90.0 nM PMID[24794751]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[24794751]
NPT2 Others Unspecified Ratio CC50/EC50 > 163.0 n.a. PMID[24794751]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 120.0 nM PMID[24933420]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 300.0 nM PMID[24805780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10000.0 nM PMID[24805780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 60.0 nM PMID[24805780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3000.0 nM PMID[24805780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 20000.0 nM PMID[24805780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 4000.0 nM PMID[24805780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1000.0 nM PMID[24805780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 150.0 nM PMID[25455487]
NPT27 Others Unspecified CC50 > 10000.0 nM PMID[25455487]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 190.0 nM PMID[25468035]
NPT27 Others Unspecified CC50 = 204003.0 nM PMID[25468035]
NPT2 Others Unspecified Ratio CC50/EC50 = 1073.7 n.a. PMID[25468035]
NPT27 Others Unspecified Ratio CC50/EC50 > 66.0 n.a. PMID[25455487]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 50.0 nM PMID[25495797]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 16100.0 nM PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 519.0 n.a. PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 66700.0 nM PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 2152.0 n.a. PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 5000.0 nM PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 161.0 n.a. PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 10000.0 nM PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC > 322.0 n.a. PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 5480.0 nM PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 177.0 n.a. PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 2800.0 nM PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC = 90.0 n.a. PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 150.0 nM PMID[25089812]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2900.0 nM PMID[25089812]
NPT2 Others Unspecified Ratio CC50/EC50 > 14.0 n.a. PMID[25089812]
NPT2 Others Unspecified Ratio CC50/EC50 > 5.0 n.a. PMID[25089812]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 31.0 nM PMID[25072874]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 120.0 nM PMID[25176191]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 100.0 nM PMID[25176191]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 250.0 nM PMID[25176328]
NPT2 Others Unspecified Ratio CC50/EC50 = 1280.0 n.a. PMID[25176328]
NPT471 Organism Trypanosoma brucei brucei Trypanosoma brucei brucei IC50 > 64000.0 nM PMID[25199582]
NPT844 Organism Trypanosoma brucei rhodesiense Trypanosoma brucei rhodesiense IC50 > 64000.0 nM PMID[25199582]
NPT27 Others Unspecified IC50 > 64000.0 nM PMID[25199582]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 144.0 nM PMID[25199582]
NPT27 Others Unspecified CC50 > 50000.0 nM PMID[25199582]
NPT580 Organism Trypanosoma cruzi Trypanosoma cruzi IC50 > 64000.0 nM PMID[25199582]
NPT1021 Organism Leishmania infantum Leishmania infantum IC50 > 64000.0 nM PMID[25199582]
NPT485 Organism Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50 = 64000.0 nM PMID[25199582]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 180.0 nM PMID[25127466]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 15000.0 nM PMID[25127466]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 310.0 nM PMID[25240095]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 7580.0 nM PMID[25240095]
NPT2 Others Unspecified Ratio CC50/EC50 = 48.0 n.a. PMID[25240095]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[25408842]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 180.0 nM PMID[25150090]
NPT2 Others Unspecified Ratio CC50/EC50 > 79.0 n.a. PMID[25150090]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 14400.0 nM PMID[25150090]
NPT2 Others Unspecified Ratio CC50/EC50 = 1.0 n.a. PMID[25150090]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 112.4 nM PMID[25418038]
NPT2 Others Unspecified Ratio CC50/EC50 > 167.0 n.a. PMID[25418038]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 19.2 nM PMID[25418038]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 10000.0 nM PMID[25418038]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 3756.0 nM PMID[25418038]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 60.0 nM PMID[25418038]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 33.0 n.a. PMID[25418038]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 1.8 n.a. PMID[25418038]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 27.0 nM PMID[25682562]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 4000.0 nM PMID[25682562]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 310.0 nM PMID[25537532]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 7590.0 nM PMID[25537532]
NPT2 Others Unspecified Ratio CC50/EC50 = 48.0 n.a. PMID[25537532]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 310.0 nM PMID[25638501]
NPT2 Others Unspecified Ratio CC50/EC50 > 50.0 n.a. PMID[25638501]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 312.0 nM PMID[25626145]
NPT2 Others Unspecified Ratio CC50/EC50 > 48.0 n.a. PMID[25626145]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 7600.0 nM PMID[25626145]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 >= 24.0 n.a. PMID[25626145]
NPT2 Others Unspecified Ratio CC50/EC50 > 2.0 n.a. PMID[25626145]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 10.0 nM PMID[24926807]
NPT2 Others Unspecified Ratio CC50/IC50 > 148.0 n.a. PMID[24926807]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) IC50 > 15000.0 nM PMID[24926807]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 310.0 nM PMID[25707013]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 7600.0 nM PMID[25707013]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 10.0 nM PMID[25946116]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 15000.0 nM PMID[25946116]
NPT2 Others Unspecified Ratio CC50/EC50 = 148.0 n.a. PMID[25946116]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 100.0 nM PMID[25970729]
NPT2 Others Unspecified Ratio CC50/EC50 > 833.3 n.a. PMID[25970729]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 244.0 nM PMID[25907370]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 11000.0 nM PMID[25907370]
NPT2 Others Unspecified Ratio CC50/EC50 > 61.0 n.a. PMID[25907370]
NPT2 Others Unspecified Ratio IC50/EC50 = 525.0 n.a. PMID[26116177]
NPT2 Others Unspecified Ratio IC50/EC50 > 250.0 n.a. PMID[26116177]
NPT2 Others Unspecified Ratio CC50/EC50 > 800.0 n.a. PMID[26116177]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 311.7 nM PMID[26385446]
NPT2 Others Unspecified Ratio CC50/EC50 > 48.0 n.a. PMID[26385446]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 2.02 ug.mL-1 PMID[26385446]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 200.0 nM PMID[26276432]
NPT2 Others Unspecified Ratio CC50/EC50 > 48.0 n.a. PMID[26276435]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 7585.0 nM PMID[26276435]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 312.0 nM PMID[26276435]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3455.0 nM PMID[26276435]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 9350.0 nM PMID[26276435]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 289.0 nM PMID[26276435]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 12429.0 nM PMID[26276435]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15021.0 nM PMID[26276435]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 280.0 nM PMID[26613134]
NPT332 Organism Human immunodeficiency virus type 2 (ISOLATE ROD) Human immunodeficiency virus type 2 (ISOLATE ROD) EC50 > 15000.0 nM PMID[26613134]
NPT2 Others Unspecified Ratio CC50/EC50 > 60.0 n.a. PMID[26613134]
NPT2 Others Unspecified Ratio CC50/EC50 = 1.0 n.a. PMID[26613134]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 260.0 nM PMID[26613134]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[26613134]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 > 15000.0 nM PMID[26613134]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 260.0 nM PMID[26802545]
NPT2 Others Unspecified Ratio CC50/EC50 > 15.02 n.a. PMID[26802545]
NPT2 Others Unspecified Ratio CC50/EC50 > 58.0 n.a. PMID[26802545]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 830.0 nM PMID[26802545]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6780.0 nM PMID[26802545]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 230.0 nM PMID[26802545]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6210.0 nM PMID[26802545]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 9610.0 nM PMID[26802545]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 7170.0 nM PMID[26802545]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity = 0.01 % PMID[26964674]
NPT2 Others Unspecified Ratio CC50/EC50 > 53.0 n.a. PMID[26994843]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 280.0 nM PMID[26994843]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15020.0 nM PMID[26994843]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 420.0 nM PMID[27108399]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity = 0.5 % PMID[27108399]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[27108399]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 26.0 nM PMID[27108399]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 310.0 nM PMID[27112451]
NPT2 Others Unspecified Ratio CC50/EC50 > 57.0 n.a. PMID[27112451]
NPT2 Others Unspecified IC50 > 375000.0 nM PMID[27112451]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 220.0 nM PMID[27234889]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. Ratio CC50/EC50 > 80.0 n.a. PMID[27234889]
NPT2 Others Unspecified IC50 = 1620.0 nM PMID[27234889]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[27234889]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 7640.0 nM PMID[27234889]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 0.075 ug.mL-1 PMID[27105027]
NPT2 Others Unspecified IC50 = 91.0 nM PMID[27287366]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 250.0 nM PMID[27541578]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 >= 7590.0 nM PMID[27541578]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. CC50 > 15020.0 nM PMID[27541578]
NPT2 Others Unspecified Ratio CC50/EC50 = 48.08 n.a. PMID[27541578]
NPT2 Others Unspecified Ratio CC50/EC50 >= 2.0 n.a. PMID[27541578]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 2107.0 nM PMID[27541578]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 5392.0 nM PMID[27541578]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 15021.0 nM PMID[27541578]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 > 15021.0 nM PMID[27541578]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 271.0 nM PMID[27541578]
NPT2 Others Unspecified Ratio CC50/EC50 > 7.0 n.a. PMID[27541578]
NPT2 Others Unspecified Ratio CC50/EC50 > 3.0 n.a. PMID[27541578]
NPT2 Others Unspecified Ratio CC50/EC50 = 1.0 n.a. PMID[27541578]
NPT2 Others Unspecified Ratio CC50/EC50 > 55.0 n.a. PMID[27541578]
NPT2 Others Unspecified IC50 = 2320.0 nM PMID[27541578]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 0.05 ug.mL-1 PMID[27647368]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 > 4.0 ug.mL-1 PMID[27647368]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. CC50 > 4.0 ug.mL-1 PMID[27647368]
NPT2 Others Unspecified Ratio CC50/IC50 > 80.0 n.a. PMID[27647368]
NPT2 Others Unspecified Ratio CC50/IC50 < 1.0 n.a. PMID[27647368]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 290.0 nM PMID[27267005]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 >= 9800.0 nM PMID[27267005]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. CC50 > 15000.0 nM PMID[27267005]
NPT2 Others Unspecified Ratio CC50/EC50 = 51.0 n.a. PMID[27267005]
NPT2 Others Unspecified Ratio CC50/EC50 <= 2.0 n.a. PMID[27267005]
NPT2 Others Unspecified Ratio CC50/EC50 > 80.0 n.a. PMID[27214512]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. CC50 > 4.0 ug.mL-1 PMID[27214512]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 > 4.0 ug.mL-1 PMID[27214512]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 0.05 ug.mL-1 PMID[27214512]
NPT2 Others Unspecified Ratio CC50/EC50 < 1.0 n.a. PMID[27214512]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 16100.0 nM PMID[27484516]
NPT2 Others Unspecified IC50 = 2100.0 nM PMID[27484516]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 31.0 nM PMID[27484516]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 66700.0 nM PMID[27484516]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 5000.0 nM PMID[27484516]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 > 10000.0 nM PMID[27484516]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 5480.0 nM PMID[27484516]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 2800.0 nM PMID[27484516]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 519.0 n.a. PMID[27484516]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 2152.0 n.a. PMID[27484516]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 161.0 n.a. PMID[27484516]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 > 322.0 n.a. PMID[27484516]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 177.0 n.a. PMID[27484516]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 90.0 n.a. PMID[27484516]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 120.0 nM PMID[27750153]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 710.0 nM PMID[27750153]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3600.0 nM PMID[27750153]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3800.0 nM PMID[27750153]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 4400.0 nM PMID[27750153]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 160.0 nM PMID[27750153]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3500.0 nM PMID[27750153]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2200.0 nM PMID[27750153]
NPT2 Others Unspecified Ratio CC50/EC50 > 127.0 n.a. PMID[27750153]
NPT2 Others Unspecified Ratio CC50/EC50 > 21.0 n.a. PMID[27750153]
NPT2 Others Unspecified Ratio CC50/EC50 > 4.0 n.a. PMID[27750153]
NPT2 Others Unspecified Ratio CC50/EC50 > 3.0 n.a. PMID[27750153]
NPT2 Others Unspecified Ratio CC50/EC50 > 95.0 n.a. PMID[27750153]
NPT2 Others Unspecified Ratio CC50/EC50 > 7.0 n.a. PMID[27750153]
NPT2 Others Unspecified IC50 = 2800.0 nM PMID[27750153]
NPT2 Others Unspecified IC50 = 200.0 nM PMID[28266845]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 84.0 nM PMID[28314598]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[28314598]
NPT2 Others Unspecified Ratio CC50/EC50 > 179.0 n.a. PMID[28314598]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1800.0 nM PMID[28314598]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 210.0 nM PMID[28314598]
NPT713 Individual Protein Bile salt export pump Homo sapiens IC50 > 135000.0 nM PMID[20829430]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 260.0 nM PMID[28254696]
NPT2 Others Unspecified Ratio CC50/EC50 > 58.0 n.a. PMID[28254696]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 830.0 nM PMID[28254696]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6780.0 nM PMID[28254696]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6220.0 nM PMID[28254696]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 9610.0 nM PMID[28254696]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 230.0 nM PMID[28254696]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 7170.0 nM PMID[28254696]
NPT2 Others Unspecified IC50 = 1390.0 nM PMID[28254696]
NPT713 Individual Protein Bile salt export pump Homo sapiens IC50 = 294600.0 nM PMID[22961681]
NPT713 Individual Protein Bile salt export pump Homo sapiens IC50 > 133000.0 nM PMID[23956101]
NPT2 Others Unspecified EC50 = 210.0 nM PMID[28314514]
NPT2 Others Unspecified Ratio CC50/EC50 = 72.0 n.a. PMID[28314514]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 3756.0 nM PMID[28628334]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 33.0 n.a. PMID[28628334]
NPT2 Others Unspecified Ratio CC50/EC50 > 167.0 n.a. PMID[28628334]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 112.4 nM PMID[28628334]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 40.0 nM PMID[28442262]
NPT2 Others Unspecified TC50 >= 10.0 uM PMID[28442262]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 10000.0 nM PMID[28442262]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 30.0 nM PMID[28442262]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 4980.0 nM PMID[28442262]
NPT2 Others Unspecified IC50 = 180.0 nM PMID[28442262]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 = 30.0 nM PMID[28442262]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 = 540.0 nM PMID[28442262]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 > 10000.0 nM PMID[28442262]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 = 350.0 nM PMID[28442262]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 250.0 nM PMID[28481112]
NPT2 Others Unspecified Ratio CC50/EC50 > 60.0 n.a. PMID[28481112]
NPT2 Others Unspecified Ratio CC50/EC50 > 7.0 n.a. PMID[28481112]
NPT2 Others Unspecified Ratio CC50/EC50 > 3.0 n.a. PMID[28481112]
NPT2 Others Unspecified Ratio CC50/EC50 > 55.0 n.a. PMID[28481112]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 180.0 nM PMID[28559060]
NPT2 Others Unspecified Ratio CC50/EC50 > 81.0 n.a. PMID[28559060]
NPT2 Others Unspecified Inhibition = 88.0 % PMID[28659246]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 24.0 nM PMID[29353724]
NPT2 Others Unspecified Ratio CC50/EC50 > 168.0 n.a. PMID[29353724]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 400.0 nM PMID[29353724]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1850.0 nM PMID[29353724]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 4000.0 nM PMID[29353724]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 58.0 nM PMID[29353724]
NPT2 Others Unspecified Ratio CC50/EC50 > 2.0 n.a. PMID[29635166]
NPT2 Others Unspecified Ratio CC50/EC50 > 64.0 n.a. PMID[29635166]
NPT2 Others Unspecified Ratio CC50/EC50 > 18.0 n.a. PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 27.6 n.a. PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 37.0 n.a. PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 23.9 n.a. PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 0.9 n.a. PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 26.1 n.a. PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 3.2 n.a. PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 7170.0 nM PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 9610.0 nM PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6210.0 nM PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 230.0 nM PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6780.0 nM PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 830.0 nM PMID[29635166]
NPT2 Others Unspecified Ratio CC50/EC50 > 58.0 n.a. PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15020.0 nM PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 260.0 nM PMID[29635166]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 180.0 nM PMID[29291935]
NPT2 Others Unspecified Ratio CC50/EC50 > 81.0 n.a. PMID[29291935]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 156.0 nM PMID[28613071]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 100000.0 nM PMID[28613071]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 532.0 nM PMID[28613071]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 250.0 nM PMID[28987601]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15020.0 nM PMID[28987601]
NPT2 Others Unspecified Ratio CC50/EC50 > 60.0 n.a. PMID[28987601]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 13.0 nM PMID[29699924]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 910.0 nM PMID[29699924]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 70.0 n.a. PMID[29699924]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 2860.0 nM PMID[29699924]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 220.0 n.a. PMID[29699924]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 22.0 nM PMID[29699924]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 = 1.7 n.a. PMID[29699924]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 < 33.9 n.a. PMID[29534929]
NPT2 Others Unspecified Ratio CC50/EC50 = 1.0 n.a. PMID[29534929]
NPT2 Others Unspecified Ratio CC50/EC50 > 34.0 n.a. PMID[29534929]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[29534929]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 440.0 nM PMID[29534929]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 125.42 nM PMID[29559197]
NPT2 Others Unspecified Ratio CC50/EC50 > 120.0 n.a. PMID[29559197]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3250.0 nM PMID[29559197]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 10260.0 nM PMID[29559197]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 280.0 nM PMID[29559197]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15020.0 nM PMID[29559197]
NPT2 Others Unspecified Ratio CC50/EC50 > 53.0 n.a. PMID[29670703]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 100.0 nM PMID[30318436]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 4000.0 nM PMID[30318436]
NPT2 Others Unspecified Ratio CC50/EC50 > 39.0 n.a. PMID[30318436]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Inhibition = 0.18 % DOI[10.21203/rs.3.rs-23951/v1]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition = 76.0 % PMID[31734023]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 235.0 nM PMID[31735575]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 11200.0 nM PMID[31735575]
NPT2 Others Unspecified Ratio CC50/EC50 > 64.0 n.a. PMID[31735575]
NPT2 Others Unspecified Ratio CC50/EC50 > 1.0 n.a. PMID[31735575]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 293.0 nM PMID[31714780]
NPT2 Others Unspecified Ratio CC50/EC50 > 51.0 n.a. PMID[31714780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2102300.0 nM PMID[31714780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 10075000.0 nM PMID[31714780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15866700.0 nM PMID[31714780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 < 5866700.0 nM PMID[31714780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 210200.0 nM PMID[31714780]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 108.0 n.a. PMID[32293182]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 9510.0 nM PMID[32293182]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 43.0 n.a. PMID[32293182]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3760.0 nM PMID[32293182]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 87.9 nM PMID[32293182]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 380.0 nM PMID[31434039]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15030.0 nM PMID[31434039]
NPT2 Others Unspecified Ratio CC50/EC50 > 39.0 n.a. PMID[31434039]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 180.0 nM PMID[31434039]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1240.0 nM PMID[31434039]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 7180.0 nM PMID[31434039]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 240.0 nM PMID[30721060]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[30721060]
NPT2 Others Unspecified Ratio CC50/EC50 > 62.0 n.a. PMID[30721060]
NPT2 Others Unspecified Ratio CC50/EC50 = 1.0 n.a. PMID[30721060]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 160.0 nM PMID[30721060]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1640.0 nM PMID[30721060]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 10900.0 nM PMID[30721060]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 239.88 nM PMID[30721060]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 120.0 nM PMID[30525601]
NPT27 Others Unspecified Ratio CC50/EC50 > 58.0 n.a. PMID[30525601]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 7000.0 nM PMID[30525601]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5600.0 nM PMID[30525601]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 = 47.0 n.a. PMID[30525601]
NPT2 Others Unspecified Ratio = 17.0 n.a. PMID[30525601]
NPT2 Others Unspecified Ratio = 82.0 n.a. PMID[30525601]
NPT2 Others Unspecified Ratio = 21.0 n.a. PMID[30525601]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 300.0 nM PMID[31281023]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 293.0 nM PMID[31421633]
NPT2 Others Unspecified Ratio CC50/EC50 > 51.0 n.a. PMID[31421633]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1990.0 nM PMID[31421633]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 9550.0 nM PMID[31421633]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15030.0 nM PMID[31421633]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 200.0 nM PMID[31421633]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 300.0 nM PMID[31557609]
NPT27 Others Unspecified Ratio CC50/IC50 = 1990.0 n.a. PMID[31557609]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 140000.0 nM PMID[31557609]
NPT27 Others Unspecified Ratio CC50/IC50 = 4.3 n.a. PMID[31557609]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 190.0 nM PMID[31557609]
NPT27 Others Unspecified Ratio CC50/IC50 = 5278.0 n.a. PMID[31557609]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 940.0 nM PMID[31557609]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 232300.0 nM PMID[31557609]
NPT27 Others Unspecified Ratio CC50/IC50 = 2.6 n.a. PMID[31557609]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 40.0 nM PMID[27390064]
NPT2 Others Unspecified Ratio IC50 > 200.0 n.a. PMID[27339173]
NPT2 Others Unspecified FC = 2.0 n.a. PMID[27339173]
NPT2 Others Unspecified IC50 > 200000.0 nM PMID[27339173]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 > 200000.0 nM PMID[27339173]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 = 100.0 nM PMID[27339173]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[27485603]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 258.36 nM PMID[27501911]
NPT2 Others Unspecified Ratio CC50/EC50 > 58.0 n.a. PMID[27501911]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 830.0 nM PMID[27501911]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6780.0 nM PMID[27501911]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6210.0 nM PMID[27501911]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 9610.0 nM PMID[27501911]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 230.0 nM PMID[27501911]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 7170.0 nM PMID[27501911]
NPT2 Others Unspecified Ratio CC50/EC50 > 18.0 n.a. PMID[27501911]
NPT2 Others Unspecified Ratio CC50/EC50 > 2.0 n.a. PMID[27501911]
NPT2 Others Unspecified Ratio CC50/EC50 > 64.0 n.a. PMID[27501911]
NPT20556 SINGLE PROTEIN Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2 Inhibition = 13.05 % DOI[10.6019/CHEMBL4495564]
NPT20556 SINGLE PROTEIN Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2 Inhibition = 16.23 % DOI[10.6019/CHEMBL4495564]
NPT20556 SINGLE PROTEIN Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2 Inhibition = -36.16 % DOI[10.6019/CHEMBL4495564]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Inhibition = 0.01 % DOI[10.6019/CHEMBL4495565]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Inhibition = -0.03 % DOI[10.6019/CHEMBL4495565]
NPT20 Organism Candida albicans Candida albicans Inhibition = 2.39 % DOI[10.6019/CHEMBL4296181]
NPT85 Organism Filobasidiella neoformans Cryptococcus neoformans Inhibition = -2.57 % DOI[10.6019/CHEMBL4296181]
NPT19 Organism Escherichia coli Escherichia coli Inhibition = -0.52 % DOI[10.6019/CHEMBL4296181]
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Inhibition = 10.08 % DOI[10.6019/CHEMBL4296181]
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Inhibition = 42.2 % DOI[10.6019/CHEMBL4296181]
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Inhibition = 29.17 % DOI[10.6019/CHEMBL4296181]
NPT2922 Organism Staphylococcus aureus subsp. aureus Staphylococcus aureus subsp. aureus Inhibition = 12.92 % DOI[10.6019/CHEMBL4296181]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 180.0 nM PMID[32197813]
NPT2 Others Unspecified Ratio CC50/EC50 > 81.0 n.a. PMID[32197813]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 IC50 > 20000.0 nM DOI[10.6019/CHEMBL4651402]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 IC50 > 19952.62 nM DOI[10.6019/CHEMBL4651402]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 110.0 nM PMID[33603971]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3.2 nM PMID[31767136]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 14.0 nM PMID[31767136]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6.7 nM PMID[31767136]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 34.0 nM PMID[31767136]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition = 77.0 % PMID[31771827]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 163.0 nM PMID[32200201]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 9513.0 nM PMID[32200201]
NPT2 Others Unspecified Ratio CC50/EC50 > 58.0 n.a. PMID[32200201]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 112.4 nM PMID[32883642]
NPT2 Others Unspecified Ratio CC50/EC50 > 167.0 n.a. PMID[32883642]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 3756.0 nM PMID[32883642]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 > 33.0 n.a. PMID[32883642]
NPT2 Others Unspecified IC50 > 20000.0 nM PMID[32883642]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 150.0 nM PMID[33279288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 151.36 nM PMID[33279288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15020.0 nM PMID[33279288]
NPT2 Others Unspecified Ratio CC50/EC50 > 100.0 n.a. PMID[33279288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 620.0 nM PMID[33279288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 3920.0 nM PMID[33279288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5050.0 nM PMID[33279288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 9070.0 nM PMID[33279288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 170.0 nM PMID[33279288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 8040.0 nM PMID[33279288]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 150.0 nM PMID[33567378]
NPT2 Others Unspecified Ratio CC50/EC50 > 100.0 n.a. PMID[33567378]
NPT2 Others Unspecified EC50 = 5053.0 nM PMID[33567378]
NPT2 Others Unspecified EC50 > 15020.0 nM PMID[33567378]
NPT2 Others Unspecified Inhibition = 50.0 % PMID[31893549]
NPT2 Others Unspecified IC50 = 130.0 nM PMID[31893549]
NPT2 Others Unspecified Inhibition = 91.0 % PMID[31893549]
NPT2 Others Unspecified Inhibition = 98.0 % PMID[31893549]
NPT2 Others Unspecified EC50 = 6.7 nM PMID[31893549]
NPT2 Others Unspecified Ratio CC50/EC50 = 14353.0 n.a. PMID[31893549]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 0.7 nM PMID[32004936]
NPT2 Others Unspecified Ratio CC50/EC50 = 33885.71 n.a. PMID[32004936]
NPT2 Others Unspecified IC50 = 980.0 nM PMID[32004936]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1400.0 nM PMID[32004936]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2580.0 nM PMID[32004936]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 80000.0 nM PMID[32004936]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 760.0 nM PMID[32004936]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 100000.0 nM PMID[32004936]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 14570.0 nM PMID[32004936]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 2870.0 nM PMID[32004936]
NPT2 Others Unspecified Ratio EC50 = 81.2 n.a. PMID[32004936]
NPT2 Others Unspecified Ratio EC50 = 149.9 n.a. PMID[32004936]
NPT2 Others Unspecified Ratio EC50 = 4657.9 n.a. PMID[32004936]
NPT2 Others Unspecified Ratio EC50 = 44.4 n.a. PMID[32004936]
NPT2 Others Unspecified Ratio EC50 > 5000.0 n.a. PMID[32004936]
NPT2 Others Unspecified Ratio EC50 = 848.0 n.a. PMID[32004936]
NPT2 Others Unspecified Ratio EC50 = 167.0 n.a. PMID[32004936]
NPT2 Others Unspecified EC50 = 161.5 nM PMID[32712537]
NPT2 Others Unspecified Ratio CC50/EC50 > 93.0 n.a. PMID[32712537]
NPT2 Others Unspecified EC50 = 3116.8 nM PMID[32712537]
NPT2 Others Unspecified EC50 = 12880.2 nM PMID[32712537]
NPT2 Others Unspecified IC50 = 826.1 nM PMID[32712537]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 164.0 nM PMID[32977301]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 15000.0 nM PMID[32977301]
NPT2 Others Unspecified Ratio CC50/EC50 > 92.0 n.a. PMID[32977301]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 1030.0 nM PMID[32977301]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5100.0 nM PMID[32977301]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 6690.0 nM PMID[32977301]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 7700.0 nM PMID[32977301]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 191.0 nM PMID[32977301]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 5410.0 nM PMID[32977301]
NPT2 Others Unspecified Ratio EC50 = 6.3 n.a. PMID[32977301]
NPT2 Others Unspecified Ratio EC50 = 31.1 n.a. PMID[32977301]
NPT2 Others Unspecified Ratio EC50 = 40.7 n.a. PMID[32977301]
NPT2 Others Unspecified Ratio EC50 >= 46.9 n.a. PMID[32977301]
NPT2 Others Unspecified Ratio EC50 = 1.2 n.a. PMID[32977301]
NPT2 Others Unspecified Ratio EC50 >= 32.9 n.a. PMID[32977301]

☑ Note for Activity Records:
☉ The quantitative biological activities were primarily integrated from ChEMBL (Version-30) database and were also directly collected from PubMed literature. PubMed PMID was provided as the reference link for each activity record.

  Chemically structural similarity: I. Similar Active Natural Products in NPASS

Top-200 similar NPs were calculated against the active-NP-set (includes 4,3285 NPs with experimentally-derived bioactivity available in NPASS)

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC191693 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID

  Chemically structural similarity: II. Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC191693 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage

  Bioactivity similarity: Similar Natural Products in NPASS

Bioactivity similarity was calculated based on bioactivity descriptors of compounds. The bioactivity descriptors were calculated by a recently developed AI algorithm Chemical Checker (CC) [Nature Biotechnology, 38:1087–1096, 2020; Nature Communications, 12:3932, 2021], which evaluated bioactivity similarities at five levels:
☉ A: chemistry similarity;
☉ B: biological targets similarity;
☉ C: networks similarity;
☉ D: cell-based bioactivity similarity;
☉ E: similarity based on clinical data.

Those 5 categories of CC bioactivity descriptors were calculated and then subjected to manifold projection using UMAP algorithm, to project all NPs on a 2-Dimensional space. The current NP was highlighted with a small circle in the 2-D map. Below figures: left-to-right, A-to-E.

A: chemistry similarity
B: biological targets similarity
C: networks similarity
D: cell-based bioactivity similarity
E: similarity based on clinical data