Target ID |
Target Type |
Target Name |
Target Organism |
Activity Type |
Activity Relation |
Value |
Unit |
Reference |
NPT605 |
Organism |
Homo sapiens |
Homo sapiens |
IC50 |
= |
178400 |
nM |
1501222 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Kd |
= |
1.995 |
nM |
6135805 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Kd |
= |
1.259 |
nM |
6135805 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Kd |
= |
2.399 |
nM |
6147415 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Kd |
= |
3.631 |
nM |
6147415 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
LD50 |
= |
29.2 |
mg/kg |
6147415 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Activity |
= |
1.76 |
|
10.1016/S0960-894X(97)00046-2 |
NPT225 |
Individual Protein |
Beta-1 adrenergic receptor |
Homo sapiens |
Ki |
= |
2.3 |
nM |
8093626 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
ED50 |
= |
0.18 |
mg/kg |
8093626 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
ED50 |
= |
22.23 |
mg/kg |
8093626 |
NPT288 |
Individual Protein |
Serotonin 1a (5-HT1a) receptor |
Rattus norvegicus |
Ki |
= |
90 |
nM |
2539480 |
NPT289 |
Individual Protein |
Serotonin 1b (5-HT1b) receptor |
Rattus norvegicus |
Ki |
= |
50 |
nM |
2539480 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
Ki |
= |
2.4 |
nM |
2539480 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
1.995 |
nM |
6130154 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
1.259 |
nM |
6130154 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
46 |
nM |
6130154 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
> |
60 |
nM |
6130154 |
NPT2840 |
Protein Family |
Adrenergic receptor alpha |
Homo sapiens |
Kd |
> |
100000 |
nM |
6124636 |
NPT2 |
Others |
Unspecified |
|
Kd |
= |
1.549 |
nM |
6124636 |
NPT2 |
Others |
Unspecified |
|
Kd |
= |
4.677 |
nM |
6124636 |
NPT288 |
Individual Protein |
Serotonin 1a (5-HT1a) receptor |
Rattus norvegicus |
Ki |
= |
113 |
nM |
8230102 |
NPT4663 |
Individual Protein |
Beta-2 adrenergic receptor |
Canis lupus familiaris |
ED50 |
= |
0.124 |
mg/kg |
6138434 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
0.143 |
mg/kg |
6138434 |
NPT5860 |
Others |
Adrenergic receptor beta; ADRB1 & ADRB2 |
Homo sapiens |
Ratio |
= |
0.043 |
|
6138434 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
0.87 |
|
6138434 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
2 |
|
3031293 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
2.399 |
nM |
2861288 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
3.388 |
nM |
2861288 |
NPT973 |
Individual Protein |
Serotonin 1b (5-HT1b) receptor |
Homo sapiens |
Ki |
> |
10000 |
nM |
9435911 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Kd |
= |
1.995 |
nM |
6146718 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Kd |
= |
1.259 |
nM |
6146718 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
68 |
% |
6146718 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
0.216 |
|
3001305 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
9.05 |
ml |
3001305 |
NPT225 |
Individual Protein |
Beta-1 adrenergic receptor |
Homo sapiens |
ID50 |
= |
0.069 |
mg/kg |
3001305 |
NPT4663 |
Individual Protein |
Beta-2 adrenergic receptor |
Canis lupus familiaris |
ID50 |
= |
0.038 |
mg/kg |
3001305 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
2.512 |
nM |
2903245 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
3.388 |
nM |
2903245 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
1.5 |
|
2903245 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Inhibition |
= |
62 |
ug kg-1 |
6106716 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Inhibition |
= |
85 |
% |
6106716 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
ED50 |
= |
0.071 |
mg/kg |
2866246 |
NPT4632 |
Individual Protein |
Beta-2 adrenergic receptor |
Rattus norvegicus |
ED50 |
= |
0.042 |
mg/kg |
2866246 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
ED30 |
> |
1000 |
ug kg-1 |
2866246 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
3.09 |
nM |
6330358 |
NPT4663 |
Individual Protein |
Beta-2 adrenergic receptor |
Canis lupus familiaris |
Kd |
= |
1.778 |
nM |
6330358 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
IC50 |
= |
12 |
nM |
1976812 |
NPT225 |
Individual Protein |
Beta-1 adrenergic receptor |
Homo sapiens |
IC50 |
= |
18 |
nM |
1976812 |
NPT4663 |
Individual Protein |
Beta-2 adrenergic receptor |
Canis lupus familiaris |
IC50 |
= |
17 |
nM |
1976812 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
2.399 |
nM |
6148422 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
3.388 |
nM |
6148422 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
1.738 |
nM |
6134834 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
3.02 |
nM |
6134834 |
NPT5860 |
Others |
Adrenergic receptor beta; ADRB1 & ADRB2 |
Homo sapiens |
Ratio |
= |
2 |
|
6134834 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Kd |
= |
7.586 |
nM |
7908697 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Kd |
= |
3.802 |
nM |
7908697 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Kd |
= |
5.012 |
nM |
9572886 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Kd |
= |
7.943 |
nM |
9572886 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
IC50 |
= |
3 |
nM |
9572886 |
NPT968 |
Protein Family |
Adrenergic receptor alpha-1 |
Rattus norvegicus |
IC50 |
> |
100000 |
nM |
9572886 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
Inhibition |
= |
100 |
% |
9572886 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Kd |
= |
2.399 |
nM |
9572886 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Kd |
= |
2630.27 |
nM |
9572886 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
IC50 |
= |
34.67 |
nM |
8230093 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
IC50 |
= |
28.84 |
nM |
8230093 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
EC50 |
= |
1911.6 |
ug |
6120233 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
EC50 |
= |
10229 |
ug |
6120233 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Ratio |
= |
12.05 |
|
6120233 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Ratio |
= |
4.67 |
|
6120233 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Ki |
> |
5000 |
nM |
1825848 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
ED50 |
= |
0.062 |
mg/kg |
6128420 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Inhibition |
= |
85 |
% |
6128420 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
2.399 |
nM |
6104730 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
3.388 |
nM |
6104730 |
NPT5860 |
Others |
Adrenergic receptor beta; ADRB1 & ADRB2 |
Homo sapiens |
Ratio |
= |
0.7 |
|
6104730 |
NPT1858 |
Individual Protein |
Dopamine D2 receptor |
Rattus norvegicus |
Ki |
> |
10000 |
nM |
2136916 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Inhibition |
= |
85 |
% |
6118435 |
NPT5860 |
Others |
Adrenergic receptor beta; ADRB1 & ADRB2 |
Homo sapiens |
ED50 |
= |
0.11 |
mg/kg |
6145801 |
NPT5860 |
Others |
Adrenergic receptor beta; ADRB1 & ADRB2 |
Homo sapiens |
ED50 |
= |
0.41 |
mg/kg |
6145801 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
ED50 |
= |
1.01E-08 |
nM |
6145801 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
3.7 |
|
6145801 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
Ki |
= |
6.5 |
nM |
2883317 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
100 |
% |
2883317 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
ED50 |
= |
0.019 |
mg/kg |
6102151 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
ED50 |
= |
0.051 |
mg/kg |
6102151 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
8.71 |
nM |
6120237 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
43.65 |
nM |
6120237 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
IC50 |
= |
4 |
nM |
3560162 |
NPT2838 |
Individual Protein |
Beta-1 adrenergic receptor |
Sus scrofa |
ED50 |
= |
0.05 |
mg/kg |
2435902 |
NPT2839 |
Individual Protein |
Beta-2 adrenergic receptor |
Sus scrofa |
ED50 |
= |
0.1 |
mg/kg |
2435902 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Ki |
> |
10000 |
nM |
8093734 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Kb |
= |
0.62 |
nM |
2878080 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
ED50 |
= |
0.2 |
mg/kg |
6130155 |
NPT1403 |
Organism |
Felis catus |
Felis catus |
ED50 |
= |
0.062 |
mg/kg |
6130155 |
NPT1403 |
Organism |
Felis catus |
Felis catus |
Inhibition |
= |
85 |
% |
6130155 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Kd |
= |
4.365 |
nM |
2884312 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
12.59 |
nM |
2884312 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
IC50 |
= |
30 |
nM |
6124637 |
NPT225 |
Individual Protein |
Beta-1 adrenergic receptor |
Homo sapiens |
ID50 |
= |
0.08 |
umol/kg |
2892934 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
1.738 |
nM |
2872332 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
0.9772 |
nM |
2872332 |
NPT5860 |
Others |
Adrenergic receptor beta; ADRB1 & ADRB2 |
Homo sapiens |
Ratio |
= |
0.56 |
|
2872332 |
NPT3056 |
Individual Protein |
Dopamine D3 receptor |
Rattus norvegicus |
Ki |
> |
5000 |
nM |
8098771 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
ED50 |
= |
62 |
mg/kg |
6131134 |
NPT1386 |
Protein Family |
Adrenergic receptor beta |
Homo sapiens |
Inhibition |
= |
85 |
% |
6131134 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Kd |
= |
37.15 |
nM |
6115057 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Kd |
= |
25.12 |
nM |
6115057 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Kd |
= |
11.22 |
nM |
6115057 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
Ki |
= |
1600 |
nM |
2909730 |
NPT668 |
Individual Protein |
P-glycoprotein 1 |
Homo sapiens |
Ki |
= |
48000 |
nM |
12477351 |
NPT668 |
Individual Protein |
P-glycoprotein 1 |
Homo sapiens |
IC50 |
= |
573000 |
nM |
12477351 |
NPT1858 |
Individual Protein |
Dopamine D2 receptor |
Rattus norvegicus |
Ki |
= |
12902 |
nM |
2966245 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
Inhibition |
= |
26 |
% |
6102605 |
NPT4333 |
Protein Family |
Adrenergic receptor beta |
Rattus norvegicus |
Inhibition |
= |
56 |
% |
6102605 |
NPT110 |
Individual Protein |
Cytochrome P450 2D6 |
Homo sapiens |
IC50 |
= |
1900 |
nM |
15993593 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Ki |
= |
3.162 |
nM |
16759089 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Ki |
= |
31.62 |
nM |
16759089 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Ki |
= |
199.53 |
nM |
16759089 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Ki |
= |
10 |
nM |
16759089 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Ki |
= |
39.81 |
nM |
16759089 |
NPT604 |
Individual Protein |
Serum albumin |
Homo sapiens |
Kd |
= |
436515.83 |
nM |
18348514 |
NPT604 |
Individual Protein |
Serum albumin |
Homo sapiens |
Kd |
= |
354813.39 |
nM |
18348514 |
NPT604 |
Individual Protein |
Serum albumin |
Homo sapiens |
Kd |
= |
660693.45 |
nM |
18348514 |
NPT604 |
Individual Protein |
Serum albumin |
Homo sapiens |
Kd |
= |
602559.59 |
nM |
18348514 |
NPT604 |
Individual Protein |
Serum albumin |
Homo sapiens |
Kd |
= |
630957.34 |
nM |
18348514 |
NPT612 |
Individual Protein |
Canalicular multispecific organic anion transporter 1 |
Homo sapiens |
Activity |
= |
69 |
% |
18457386 |
NPT613 |
Individual Protein |
Solute carrier family 22 member 1 |
Homo sapiens |
IC50 |
= |
63200 |
nM |
18788725 |
NPT613 |
Individual Protein |
Solute carrier family 22 member 1 |
Homo sapiens |
Inhibition |
= |
55.4 |
% |
18788725 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
1.05 |
mg/kg |
19131251 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Ki |
= |
9700 |
nM |
19131251 |
NPT6026 |
Individual Protein |
Aromatic peroxygenase |
Agrocybe aegerita |
Activity |
= |
13.6 |
% |
19394224 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
0.5 |
% |
19394224 |
NPT226 |
Individual Protein |
Beta-2 adrenergic receptor |
Homo sapiens |
Kd |
= |
0.79 |
nM |
19168263 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
7.6 |
mg/kg |
19447527 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
1.05 |
mg/kg |
19647907 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
17.2 |
% |
20170117 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
13.9 |
% |
20170117 |
NPT492 |
Cell Line |
Caco-2 |
Homo sapiens |
Ratio |
= |
1.3 |
|
19762238 |
NPT605 |
Organism |
Homo sapiens |
Homo sapiens |
Activity |
= |
0.99 |
% |
20022146 |
NPT306 |
Cell Line |
PC-3 |
Homo sapiens |
FC |
= |
0.986 |
|
16680159 |
NPT312 |
Organism |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Potency |
= |
11582.1 |
nM |
PubChem BioAssay data set |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
41.4 |
% |
21211966 |
NPT5 |
Individual Protein |
Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 |
Homo sapiens |
Potency |
|
3162.3 |
nM |
PubChem BioAssay data set |
NPT1139 |
Individual Protein |
Arachidonate 15-lipoxygenase, type II |
Homo sapiens |
Potency |
|
25118.9 |
nM |
PubChem BioAssay data set |
NPT242 |
Individual Protein |
Dopamine D1 receptor |
Homo sapiens |
Potency |
|
14125.4 |
nM |
PubChem BioAssay data set |
NPT492 |
Cell Line |
Caco-2 |
Homo sapiens |
Ratio |
= |
1.21 |
|
21764308 |
NPT227 |
Individual Protein |
Beta-3 adrenergic receptor |
Homo sapiens |
Kd |
= |
162.18 |
nM |
21870877 |
NPT226 |
Individual Protein |
Beta-2 adrenergic receptor |
Homo sapiens |
Kd |
= |
0.2399 |
nM |
21870877 |
NPT225 |
Individual Protein |
Beta-1 adrenergic receptor |
Homo sapiens |
Kd |
= |
199.53 |
nM |
21870877 |
NPT225 |
Individual Protein |
Beta-1 adrenergic receptor |
Homo sapiens |
Kd |
= |
1.82 |
nM |
21870877 |
NPT227 |
Individual Protein |
Beta-3 adrenergic receptor |
Homo sapiens |
Kd |
= |
213.8 |
nM |
21870877 |
NPT226 |
Individual Protein |
Beta-2 adrenergic receptor |
Homo sapiens |
Kd |
= |
0.6026 |
nM |
21870877 |
NPT225 |
Individual Protein |
Beta-1 adrenergic receptor |
Homo sapiens |
Kd |
= |
6.026 |
nM |
21870877 |
NPT478 |
Individual Protein |
Ataxin-2 |
Homo sapiens |
Potency |
|
14125.4 |
nM |
PubChem BioAssay data set |
NPT7 |
Individual Protein |
Thioredoxin reductase 1, cytoplasmic |
Rattus norvegicus |
Potency |
|
39810.7 |
nM |
PubChem BioAssay data set |
NPT7 |
Individual Protein |
Thioredoxin reductase 1, cytoplasmic |
Rattus norvegicus |
Potency |
|
44668.4 |
nM |
PubChem BioAssay data set |
NPT519 |
Cell Line |
SH-SY5Y |
Homo sapiens |
Potency |
|
3981.1 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
29081 |
nM |
PubChem BioAssay data set |
NPT901 |
Individual Protein |
UDP-glucuronosyltransferase 1-1 |
Homo sapiens |
Activity |
= |
0 |
pm/min/mg |
10836148 |
NPT703 |
Individual Protein |
UDP-glucuronosyltransferase 1-9 |
Homo sapiens |
Activity |
= |
40 |
pm/min/mg |
10836148 |
NPT700 |
Individual Protein |
UDP-glucuronosyltransferase 2B10 |
Homo sapiens |
Activity |
= |
0 |
pm/min/mg |
10836148 |
NPT701 |
Individual Protein |
UDP-glucuronosyltransferase 2B4 |
Homo sapiens |
Activity |
= |
0 |
pm/min/mg |
10836148 |
NPT697 |
Individual Protein |
UDP-glucuronosyltransferase 2B7 |
Homo sapiens |
Activity |
= |
0.2 |
pm/min/mg |
10836148 |
NPT225 |
Individual Protein |
Beta-1 adrenergic receptor |
Homo sapiens |
IC50 |
= |
2.543 |
nM |
DrugMatrix in vitro pharmacology data |
NPT225 |
Individual Protein |
Beta-1 adrenergic receptor |
Homo sapiens |
Ki |
= |
1.468 |
nM |
DrugMatrix in vitro pharmacology data |
NPT226 |
Individual Protein |
Beta-2 adrenergic receptor |
Homo sapiens |
IC50 |
= |
1.116 |
nM |
DrugMatrix in vitro pharmacology data |
NPT226 |
Individual Protein |
Beta-2 adrenergic receptor |
Homo sapiens |
Ki |
= |
0.767 |
nM |
DrugMatrix in vitro pharmacology data |
NPT227 |
Individual Protein |
Beta-3 adrenergic receptor |
Homo sapiens |
IC50 |
= |
132 |
nM |
DrugMatrix in vitro pharmacology data |
NPT227 |
Individual Protein |
Beta-3 adrenergic receptor |
Homo sapiens |
Ki |
= |
99 |
nM |
DrugMatrix in vitro pharmacology data |
NPT208 |
Individual Protein |
Cytochrome P450 1A2 |
Homo sapiens |
IC50 |
= |
4000 |
nM |
DrugMatrix in vitro pharmacology data |
NPT110 |
Individual Protein |
Cytochrome P450 2D6 |
Homo sapiens |
IC50 |
= |
2000 |
nM |
DrugMatrix in vitro pharmacology data |
NPT288 |
Individual Protein |
Serotonin 1a (5-HT1a) receptor |
Rattus norvegicus |
IC50 |
= |
243 |
nM |
DrugMatrix in vitro pharmacology data |
NPT288 |
Individual Protein |
Serotonin 1a (5-HT1a) receptor |
Rattus norvegicus |
Ki |
= |
139 |
nM |
DrugMatrix in vitro pharmacology data |
NPT290 |
Individual Protein |
Serotonin 2a (5-HT2a) receptor |
Homo sapiens |
IC50 |
= |
1466 |
nM |
DrugMatrix in vitro pharmacology data |
NPT290 |
Individual Protein |
Serotonin 2a (5-HT2a) receptor |
Homo sapiens |
Ki |
= |
419 |
nM |
DrugMatrix in vitro pharmacology data |
NPT291 |
Individual Protein |
Serotonin 2b (5-HT2b) receptor |
Homo sapiens |
IC50 |
= |
342 |
nM |
DrugMatrix in vitro pharmacology data |
NPT291 |
Individual Protein |
Serotonin 2b (5-HT2b) receptor |
Homo sapiens |
Ki |
= |
218 |
nM |
DrugMatrix in vitro pharmacology data |
NPT292 |
Individual Protein |
Serotonin 2c (5-HT2c) receptor |
Homo sapiens |
IC50 |
= |
2294 |
nM |
DrugMatrix in vitro pharmacology data |
NPT292 |
Individual Protein |
Serotonin 2c (5-HT2c) receptor |
Homo sapiens |
Ki |
= |
1202 |
nM |
DrugMatrix in vitro pharmacology data |
NPT294 |
Individual Protein |
Serotonin 6 (5-HT6) receptor |
Homo sapiens |
IC50 |
= |
3065 |
nM |
DrugMatrix in vitro pharmacology data |
NPT294 |
Individual Protein |
Serotonin 6 (5-HT6) receptor |
Homo sapiens |
Ki |
= |
1423 |
nM |
DrugMatrix in vitro pharmacology data |
NPT295 |
Individual Protein |
Serotonin transporter |
Homo sapiens |
IC50 |
= |
380 |
nM |
DrugMatrix in vitro pharmacology data |
NPT295 |
Individual Protein |
Serotonin transporter |
Homo sapiens |
Ki |
= |
202 |
nM |
DrugMatrix in vitro pharmacology data |
NPT296 |
Individual Protein |
Sigma opioid receptor |
Homo sapiens |
IC50 |
= |
2870 |
nM |
DrugMatrix in vitro pharmacology data |
NPT296 |
Individual Protein |
Sigma opioid receptor |
Homo sapiens |
Ki |
= |
1206 |
nM |
DrugMatrix in vitro pharmacology data |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
3467 |
nM |
DrugMatrix in vitro pharmacology data |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
2134 |
nM |
DrugMatrix in vitro pharmacology data |
NPT6 |
Organism |
Plasmodium falciparum |
Plasmodium falciparum |
IC50 |
= |
37680 |
nM |
22196513 |
NPT485 |
Organism |
Plasmodium falciparum (isolate K1 / Thailand) |
Plasmodium falciparum K1 |
IC50 |
= |
10190 |
nM |
22196513 |
NPT6 |
Organism |
Plasmodium falciparum |
Plasmodium falciparum |
Ratio IC50 |
= |
0.27 |
|
22196513 |
NPT1161 |
Cell Line |
CHO |
Cricetulus griseus |
IC50 |
> |
300000 |
nM |
22196513 |
NPT6 |
Organism |
Plasmodium falciparum |
Plasmodium falciparum |
Activity |
= |
5.35 |
% |
22196513 |
NPT6 |
Organism |
Plasmodium falciparum |
Plasmodium falciparum |
Activity |
= |
-3.48 |
% |
22196513 |
NPT492 |
Cell Line |
Caco-2 |
Homo sapiens |
Ratio |
= |
1.27 |
|
22464423 |
NPT492 |
Cell Line |
Caco-2 |
Homo sapiens |
Ratio |
= |
0.78 |
|
22464423 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
1.05 |
mg/kg |
22381672 |
NPT433 |
Subcellular |
Liver microsomes |
Homo sapiens |
Activity |
= |
0.094 |
nmol |
22931300 |
NPT748 |
Individual Protein |
Bile acid transporter |
Homo sapiens |
IC50 |
= |
5500 |
nM |
10565843 |
NPT478 |
Individual Protein |
Ataxin-2 |
Homo sapiens |
Potency |
|
22387.2 |
nM |
PubChem BioAssay data set |
NPT622 |
Individual Protein |
Solute carrier organic anion transporter family member 2B1 |
Homo sapiens |
Inhibition |
= |
10.1 |
% |
22541068 |
NPT72 |
Individual Protein |
Solute carrier organic anion transporter family member 1B3 |
Homo sapiens |
Inhibition |
= |
12.8 |
% |
22541068 |
NPT73 |
Individual Protein |
Solute carrier organic anion transporter family member 1B1 |
Homo sapiens |
Inhibition |
= |
8.9 |
% |
22541068 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Ki |
= |
3 |
nM |
10.1007/s00044-008-9094-3 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
400 |
bpm |
10.1007/s00044-010-9374-6 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
333 |
bpm |
10.1007/s00044-010-9374-6 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
0.13 |
mV |
10.1007/s00044-010-9374-6 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
0.04 |
mV |
10.1007/s00044-010-9374-6 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
0.02 |
mV |
10.1007/s00044-010-9374-6 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Inhibition |
= |
-1.16 |
% |
10.1007/s00044-012-0099-6 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Inhibition |
= |
63.91 |
% |
10.1007/s00044-012-0099-6 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED50 |
= |
1.05 |
mg/kg |
23245804 |
NPT171 |
Cell Line |
MRC5 |
Homo sapiens |
GI50 |
= |
150000 |
nM |
23462711 |
NPT2 |
Others |
Unspecified |
|
GI50 |
= |
109000 |
nM |
23462711 |
NPT82 |
Cell Line |
MDA-MB-231 |
Homo sapiens |
GI50 |
= |
205000 |
nM |
23462711 |
NPT2 |
Others |
Unspecified |
|
GI50 |
= |
149000 |
nM |
23462711 |
NPT2 |
Others |
Unspecified |
|
Potency |
|
16360.1 |
nM |
PubChem BioAssay data set |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
362.3 |
bpm |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
360.1 |
bpm |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
349.6 |
bpm |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
350.6 |
bpm |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
339.9 |
bpm |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
340 |
bpm |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
132.6 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
120.9 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
108.3 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
116.8 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
122.6 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
145 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
116.9 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
100.3 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
88.3 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
94.1 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
105.5 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
127.2 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
163.9 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
161 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
158.4 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
160.6 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
156.8 |
mmHg |
23538234 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
168.7 |
mmHg |
23538234 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Inhibition |
= |
73.8 |
% |
23538234 |
NPT4558 |
Individual Protein |
Beta-1 adrenergic receptor |
Rattus norvegicus |
Inhibition |
= |
49.7 |
% |
23538234 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
7 |
nM |
23787101 |
NPT226 |
Individual Protein |
Beta-2 adrenergic receptor |
Homo sapiens |
Ki |
= |
3.69 |
nM |
24326276 |
NPT226 |
Individual Protein |
Beta-2 adrenergic receptor |
Homo sapiens |
Ki |
= |
0.46 |
nM |
24326276 |
NPT857 |
Cell Line |
LLC-PK1 |
Sus scrofa |
Ratio |
= |
2 |
|
24397738 |
NPT104 |
Individual Protein |
Cerebroside-sulfatase |
Homo sapiens |
Potency |
|
2133.1 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
19952.6 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
22387.2 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
5623.4 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
1.6 |
|
37339 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
9.55 |
nM |
34040 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
14.13 |
nM |
34040 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
14.79 |
nM |
34040 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
FC |
= |
1 |
|
34040 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
92.56 |
mmHg |
24637077 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
79.43 |
mmHg |
24637077 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
62.96 |
mmHg |
24637077 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
65.87 |
mmHg |
24637077 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
70.21 |
mmHg |
24637077 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
195.12 |
mmHg |
24637077 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
171.73 |
mmHg |
24637077 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
148.53 |
mmHg |
24637077 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
120.32 |
mmHg |
24637077 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
152.26 |
mmHg |
24637077 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
95 |
% |
17752 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Inhibition |
= |
32 |
% |
17752 |
NPT1403 |
Organism |
Felis catus |
Felis catus |
Inhibition |
= |
87 |
% |
17752 |
NPT1403 |
Organism |
Felis catus |
Felis catus |
Inhibition |
= |
100 |
% |
17752 |
NPT1403 |
Organism |
Felis catus |
Felis catus |
Inhibition |
= |
85 |
% |
17752 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Inhibition |
= |
100 |
% |
17752 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
Inhibition |
= |
93 |
% |
17752 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
LD50 |
= |
35 |
mg/kg |
17752 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
1.995 |
nM |
31474 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
1.38 |
nM |
31474 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
0.01 |
ug/ml |
31485 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
0.31 |
10'-3mg/ml |
31485 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
12 |
mmHg |
42797 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
7 |
mmHg |
42797 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
14 |
mmHg |
42797 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
ED50 |
= |
0.019 |
mg/kg |
42797 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
ED50 |
= |
0.051 |
mg/kg |
42797 |
NPT2 |
Others |
Unspecified |
|
Kd |
= |
6.31 |
nM |
15112 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Activity |
= |
141 |
mmHg |
15112 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Activity |
= |
119 |
mmHg |
15112 |
NPT1403 |
Organism |
Felis catus |
Felis catus |
Activity |
= |
45 |
% |
22756 |
NPT1403 |
Organism |
Felis catus |
Felis catus |
Activity |
= |
-100 |
% |
22756 |
NPT4914 |
Individual Protein |
Beta-2 adrenergic receptor |
Cavia porcellus |
Kd |
= |
240.88 |
nM |
22756 |
NPT4913 |
Individual Protein |
Beta-1 adrenergic receptor |
Cavia porcellus |
Kd |
= |
253.4 |
nM |
22756 |
NPT938 |
Organism |
Cavia porcellus |
Cavia porcellus |
Activity |
= |
117 |
mmHg |
15112 |
NPT1403 |
Organism |
Felis catus |
Felis catus |
ED50 |
= |
62 |
mg/kg |
16137 |
NPT1403 |
Organism |
Felis catus |
Felis catus |
Inhibition |
= |
85 |
% |
16137 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
98.4 |
% |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
95.8 |
% |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
90.7 |
% |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
96.6 |
% |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
40.5 |
% |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
80.8 |
% |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
85.2 |
% |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
63.5 |
% |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
62 |
% |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
Inhibition |
= |
24.7 |
% |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
ED50 |
= |
0.09 |
mg/kg |
22752 |
NPT1016 |
Organism |
Canis familiaris |
Canis lupus familiaris |
ED50 |
= |
0.06 |
mg/kg |
22752 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
1 |
|
25738882 |
NPT2856 |
Individual Protein |
Sodium channel protein type V alpha subunit |
Homo sapiens |
IC50 |
= |
2100 |
nM |
21300721 |
NPT1305 |
Individual Protein |
Voltage-dependent L-type calcium channel subunit alpha-1C |
Cavia porcellus |
IC50 |
= |
18000 |
nM |
21300721 |
NPT98 |
Individual Protein |
HERG |
Homo sapiens |
IC50 |
= |
2828 |
nM |
21300721 |
NPT1305 |
Individual Protein |
Voltage-dependent L-type calcium channel subunit alpha-1C |
Cavia porcellus |
IC50 |
= |
18000 |
nM |
22761000 |
NPT2691 |
Individual Protein |
Voltage-gated L-type calcium channel alpha-1C subunit |
Homo sapiens |
IC50 |
= |
21000 |
nM |
22761000 |
NPT627 |
Individual Protein |
Cytochrome P450 2B6 |
Homo sapiens |
Inhibition |
< |
10 |
% |
21467212 |
NPT628 |
Individual Protein |
Cytochrome P450 2C8 |
Homo sapiens |
Inhibition |
< |
10 |
% |
21467212 |
NPT712 |
Individual Protein |
Bile salt export pump |
Rattus norvegicus |
IC50 |
> |
1000000 |
nM |
21965623 |
NPT1463 |
Individual Protein |
Cytochrome P450 2J2 |
Homo sapiens |
IC50 |
> |
50000 |
nM |
23033255 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
1.5 |
|
21071520 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
1 |
|
21071520 |
NPT212 |
Individual Protein |
Cytochrome P450 2C9 |
Homo sapiens |
Inhibition |
< |
10 |
% |
21467212 |
NPT713 |
Individual Protein |
Bile salt export pump |
Homo sapiens |
IC50 |
> |
1000000 |
nM |
21965623 |
NPT213 |
Individual Protein |
Cytochrome P450 2C19 |
Homo sapiens |
Inhibition |
< |
10 |
% |
21467212 |
NPT110 |
Individual Protein |
Cytochrome P450 2D6 |
Homo sapiens |
Inhibition |
< |
10 |
% |
21467212 |
NPT109 |
Individual Protein |
Cytochrome P450 3A4 |
Homo sapiens |
Inhibition |
< |
10 |
% |
21467212 |
NPT208 |
Individual Protein |
Cytochrome P450 1A2 |
Homo sapiens |
Inhibition |
= |
25 |
% |
21467212 |
NPT492 |
Cell Line |
Caco-2 |
Homo sapiens |
Ratio |
= |
3.1 |
|
26344593 |
NPT492 |
Cell Line |
Caco-2 |
Homo sapiens |
Ratio |
= |
3.1 |
|
26363868 |
NPT226 |
Individual Protein |
Beta-2 adrenergic receptor |
Homo sapiens |
IC50 |
= |
50.12 |
nM |
26565745 |
NPT225 |
Individual Protein |
Beta-1 adrenergic receptor |
Homo sapiens |
IC50 |
= |
251.19 |
nM |
26565745 |
NPT92 |
Individual Protein |
Serotonin 1a (5-HT1a) receptor |
Homo sapiens |
IC50 |
= |
3981.07 |
nM |
26565745 |
NPT973 |
Individual Protein |
Serotonin 1b (5-HT1b) receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT290 |
Individual Protein |
Serotonin 2a (5-HT2a) receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT291 |
Individual Protein |
Serotonin 2b (5-HT2b) receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT292 |
Individual Protein |
Serotonin 2c (5-HT2c) receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT294 |
Individual Protein |
Serotonin 6 (5-HT6) receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT1785 |
Individual Protein |
Serotonin 7 (5-HT7) receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT1788 |
Individual Protein |
Alpha-1a adrenergic receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT222 |
Individual Protein |
Alpha-2a adrenergic receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT224 |
Individual Protein |
Alpha-2c adrenergic receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT4358 |
Individual Protein |
Type-1 angiotensin II receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT303 |
Individual Protein |
Vasopressin V1a receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT239 |
Individual Protein |
Cholecystokinin A receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT264 |
Individual Protein |
Muscarinic acetylcholine receptor M3 |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT262 |
Individual Protein |
Muscarinic acetylcholine receptor M1 |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT263 |
Individual Protein |
Muscarinic acetylcholine receptor M2 |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT242 |
Individual Protein |
Dopamine D1 receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT243 |
Individual Protein |
Dopamine D2 receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT247 |
Individual Protein |
Endothelin receptor ET-A |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT271 |
Individual Protein |
Delta opioid receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT272 |
Individual Protein |
Kappa opioid receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT145 |
Individual Protein |
Mu opioid receptor |
Homo sapiens |
IC50 |
> |
5011.87 |
nM |
26565745 |
NPT973 |
Individual Protein |
Serotonin 1b (5-HT1b) receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT290 |
Individual Protein |
Serotonin 2a (5-HT2a) receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT291 |
Individual Protein |
Serotonin 2b (5-HT2b) receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT292 |
Individual Protein |
Serotonin 2c (5-HT2c) receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT294 |
Individual Protein |
Serotonin 6 (5-HT6) receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT1785 |
Individual Protein |
Serotonin 7 (5-HT7) receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT217 |
Individual Protein |
Adenosine A2a receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT218 |
Individual Protein |
Adenosine A3 receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT1788 |
Individual Protein |
Alpha-1a adrenergic receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT222 |
Individual Protein |
Alpha-2a adrenergic receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT224 |
Individual Protein |
Alpha-2c adrenergic receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT4358 |
Individual Protein |
Type-1 angiotensin II receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT303 |
Individual Protein |
Vasopressin V1a receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT239 |
Individual Protein |
Cholecystokinin A receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT264 |
Individual Protein |
Muscarinic acetylcholine receptor M3 |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT262 |
Individual Protein |
Muscarinic acetylcholine receptor M1 |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT263 |
Individual Protein |
Muscarinic acetylcholine receptor M2 |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT242 |
Individual Protein |
Dopamine D1 receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT243 |
Individual Protein |
Dopamine D2 receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT247 |
Individual Protein |
Endothelin receptor ET-A |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT271 |
Individual Protein |
Delta opioid receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT272 |
Individual Protein |
Kappa opioid receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT145 |
Individual Protein |
Mu opioid receptor |
Homo sapiens |
EC50 |
> |
5011.87 |
nM |
26565745 |
NPT109 |
Individual Protein |
Cytochrome P450 3A4 |
Homo sapiens |
IC50 |
> |
10000 |
nM |
26565745 |
NPT110 |
Individual Protein |
Cytochrome P450 2D6 |
Homo sapiens |
IC50 |
= |
5011.87 |
nM |
26565745 |
NPT208 |
Individual Protein |
Cytochrome P450 1A2 |
Homo sapiens |
IC50 |
> |
10000 |
nM |
26565745 |
NPT213 |
Individual Protein |
Cytochrome P450 2C19 |
Homo sapiens |
IC50 |
> |
10000 |
nM |
26565745 |
NPT628 |
Individual Protein |
Cytochrome P450 2C8 |
Homo sapiens |
IC50 |
> |
10000 |
nM |
26565745 |
NPT212 |
Individual Protein |
Cytochrome P450 2C9 |
Homo sapiens |
IC50 |
> |
10000 |
nM |
26565745 |
NPT616 |
Cell Line |
MDCK |
Canis lupus familiaris |
Ratio |
= |
1.1 |
|
26565745 |
NPT65 |
Cell Line |
HepG2 |
Homo sapiens |
EC20 |
> |
0.1 |
nM |
26565745 |