Organism ID | Organism Name | Taxonomy Level | Family | SuperKingdom | Isolation Part | Collection Location | Collection Time | Reference |
---|---|---|---|---|---|---|---|---|
NPO28928 | Piper nigrum | Species | Piperaceae | Eukaryota | TM-MC* |
Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT163 | Individual Protein | Nuclear factor NF-kappa-B p105 subunit | Homo sapiens | Potency | = | 3162.3 | nM | PubChem BioAssay data set |
NPT210 | Individual Protein | Thyroid stimulating hormone receptor | Homo sapiens | Potency | = | 5011.9 | nM | PubChem BioAssay data set |
NPT95 | Individual Protein | Muscarinic acetylcholine receptor M1 | Rattus norvegicus | Potency | = | 3981.1 | nM | PubChem BioAssay data set |
NPT110 | Individual Protein | Cytochrome P450 2D6 | Homo sapiens | Potency | = | 6309.6 | nM | PubChem BioAssay data set |
NPT110 | Individual Protein | Cytochrome P450 2D6 | Homo sapiens | Potency | = | 10000 | nM | PubChem BioAssay data set |
NPT443 | Individual Protein | Histone acetyltransferase GCN5 | Homo sapiens | Potency | 251.2 | nM | PubChem BioAssay data set | |
NPT1139 | Individual Protein | Arachidonate 15-lipoxygenase, type II | Homo sapiens | Potency | 15848.9 | nM | PubChem BioAssay data set | |
NPT110 | Individual Protein | Cytochrome P450 2D6 | Homo sapiens | AC50 | = | 6309.57 | nM | PubChem BioAssay data set |
NPT208 | Individual Protein | Cytochrome P450 1A2 | Homo sapiens | AC50 | = | 7943.28 | nM | PubChem BioAssay data set |
NPT110 | Individual Protein | Cytochrome P450 2D6 | Homo sapiens | AC50 | = | 10000 | nM | PubChem BioAssay data set |
NPT208 | Individual Protein | Cytochrome P450 1A2 | Homo sapiens | AC50 | = | 3162.28 | nM | PubChem BioAssay data set |
NPT2 | Others | Unspecified | Potency | 25929 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 7943.3 | nM | PubChem BioAssay data set |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC136112 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
1.0 | High Similarity | NPC141739 |
0.9667 | High Similarity | NPC320242 |
0.9206 | High Similarity | NPC97870 |
0.9206 | High Similarity | NPC307123 |
0.9206 | High Similarity | NPC247018 |
0.9147 | High Similarity | NPC318591 |
0.9147 | High Similarity | NPC231163 |
0.8382 | Intermediate Similarity | NPC204546 |
0.813 | Intermediate Similarity | NPC26524 |
0.8083 | Intermediate Similarity | NPC194034 |
0.8 | Intermediate Similarity | NPC328267 |
0.7787 | Intermediate Similarity | NPC186469 |
0.7724 | Intermediate Similarity | NPC97811 |
0.771 | Intermediate Similarity | NPC211992 |
0.7686 | Intermediate Similarity | NPC108875 |
0.7686 | Intermediate Similarity | NPC38079 |
0.7652 | Intermediate Similarity | NPC298486 |
0.7623 | Intermediate Similarity | NPC470393 |
0.76 | Intermediate Similarity | NPC46844 |
0.7578 | Intermediate Similarity | NPC10286 |
0.7578 | Intermediate Similarity | NPC213 |
0.754 | Intermediate Similarity | NPC21890 |
0.7521 | Intermediate Similarity | NPC51633 |
0.752 | Intermediate Similarity | NPC24777 |
0.7483 | Intermediate Similarity | NPC160931 |
0.7483 | Intermediate Similarity | NPC37205 |
0.748 | Intermediate Similarity | NPC115379 |
0.748 | Intermediate Similarity | NPC42383 |
0.7464 | Intermediate Similarity | NPC329595 |
0.7464 | Intermediate Similarity | NPC326599 |
0.7462 | Intermediate Similarity | NPC137096 |
0.7459 | Intermediate Similarity | NPC192596 |
0.7417 | Intermediate Similarity | NPC313918 |
0.7417 | Intermediate Similarity | NPC95755 |
0.741 | Intermediate Similarity | NPC274732 |
0.7405 | Intermediate Similarity | NPC329980 |
0.7398 | Intermediate Similarity | NPC304761 |
0.7398 | Intermediate Similarity | NPC150254 |
0.7398 | Intermediate Similarity | NPC226778 |
0.7398 | Intermediate Similarity | NPC147000 |
0.7385 | Intermediate Similarity | NPC290470 |
0.7385 | Intermediate Similarity | NPC154256 |
0.7368 | Intermediate Similarity | NPC473875 |
0.736 | Intermediate Similarity | NPC251306 |
0.7355 | Intermediate Similarity | NPC100870 |
0.7333 | Intermediate Similarity | NPC140359 |
0.7333 | Intermediate Similarity | NPC255253 |
0.7333 | Intermediate Similarity | NPC13020 |
0.7328 | Intermediate Similarity | NPC120075 |
0.7323 | Intermediate Similarity | NPC95977 |
0.7302 | Intermediate Similarity | NPC146530 |
0.7293 | Intermediate Similarity | NPC263835 |
0.7293 | Intermediate Similarity | NPC321133 |
0.7292 | Intermediate Similarity | NPC83289 |
0.7292 | Intermediate Similarity | NPC189724 |
0.7292 | Intermediate Similarity | NPC212850 |
0.729 | Intermediate Similarity | NPC469479 |
0.7287 | Intermediate Similarity | NPC301735 |
0.7286 | Intermediate Similarity | NPC208757 |
0.7285 | Intermediate Similarity | NPC203424 |
0.7285 | Intermediate Similarity | NPC206372 |
0.7273 | Intermediate Similarity | NPC283616 |
0.7266 | Intermediate Similarity | NPC55300 |
0.7266 | Intermediate Similarity | NPC166837 |
0.7239 | Intermediate Similarity | NPC475529 |
0.7237 | Intermediate Similarity | NPC477564 |
0.7237 | Intermediate Similarity | NPC2295 |
0.7237 | Intermediate Similarity | NPC233926 |
0.7236 | Intermediate Similarity | NPC327226 |
0.7226 | Intermediate Similarity | NPC158900 |
0.7218 | Intermediate Similarity | NPC256369 |
0.7209 | Intermediate Similarity | NPC165646 |
0.7206 | Intermediate Similarity | NPC474130 |
0.7203 | Intermediate Similarity | NPC318429 |
0.72 | Intermediate Similarity | NPC473855 |
0.72 | Intermediate Similarity | NPC8302 |
0.7188 | Intermediate Similarity | NPC137685 |
0.7185 | Intermediate Similarity | NPC226712 |
0.7174 | Intermediate Similarity | NPC236347 |
0.7174 | Intermediate Similarity | NPC322366 |
0.7174 | Intermediate Similarity | NPC323775 |
0.7163 | Intermediate Similarity | NPC470392 |
0.7153 | Intermediate Similarity | NPC253429 |
0.7153 | Intermediate Similarity | NPC62101 |
0.7153 | Intermediate Similarity | NPC95733 |
0.7152 | Intermediate Similarity | NPC47672 |
0.7143 | Intermediate Similarity | NPC326801 |
0.7143 | Intermediate Similarity | NPC262641 |
0.7143 | Intermediate Similarity | NPC101503 |
0.7143 | Intermediate Similarity | NPC5932 |
0.7134 | Intermediate Similarity | NPC124433 |
0.7134 | Intermediate Similarity | NPC293871 |
0.7133 | Intermediate Similarity | NPC264956 |
0.7132 | Intermediate Similarity | NPC204535 |
0.7132 | Intermediate Similarity | NPC195873 |
0.7132 | Intermediate Similarity | NPC46586 |
0.7132 | Intermediate Similarity | NPC71090 |
0.7122 | Intermediate Similarity | NPC198798 |
0.7114 | Intermediate Similarity | NPC245974 |
0.7111 | Intermediate Similarity | NPC318357 |
0.7109 | Intermediate Similarity | NPC290566 |
0.7109 | Intermediate Similarity | NPC474272 |
0.7109 | Intermediate Similarity | NPC145638 |
0.7101 | Intermediate Similarity | NPC29477 |
0.7099 | Intermediate Similarity | NPC235250 |
0.7099 | Intermediate Similarity | NPC161696 |
0.7095 | Intermediate Similarity | NPC247298 |
0.7095 | Intermediate Similarity | NPC294249 |
0.709 | Intermediate Similarity | NPC163036 |
0.7089 | Intermediate Similarity | NPC469505 |
0.7087 | Intermediate Similarity | NPC233320 |
0.7087 | Intermediate Similarity | NPC258171 |
0.708 | Intermediate Similarity | NPC217277 |
0.708 | Intermediate Similarity | NPC211218 |
0.7073 | Intermediate Similarity | NPC471576 |
0.7071 | Intermediate Similarity | NPC283079 |
0.7071 | Intermediate Similarity | NPC471306 |
0.7071 | Intermediate Similarity | NPC471321 |
0.7068 | Intermediate Similarity | NPC164386 |
0.7059 | Intermediate Similarity | NPC290451 |
0.7059 | Intermediate Similarity | NPC127389 |
0.7055 | Intermediate Similarity | NPC477838 |
0.7055 | Intermediate Similarity | NPC477837 |
0.7042 | Intermediate Similarity | NPC471953 |
0.704 | Intermediate Similarity | NPC305205 |
0.7037 | Intermediate Similarity | NPC60589 |
0.7037 | Intermediate Similarity | NPC469708 |
0.7037 | Intermediate Similarity | NPC232295 |
0.7034 | Intermediate Similarity | NPC474673 |
0.7031 | Intermediate Similarity | NPC241549 |
0.7029 | Intermediate Similarity | NPC109822 |
0.7029 | Intermediate Similarity | NPC48990 |
0.7029 | Intermediate Similarity | NPC94276 |
0.7029 | Intermediate Similarity | NPC114901 |
0.7029 | Intermediate Similarity | NPC293701 |
0.7021 | Intermediate Similarity | NPC97326 |
0.7016 | Intermediate Similarity | NPC214200 |
0.7016 | Intermediate Similarity | NPC228400 |
0.7008 | Intermediate Similarity | NPC41594 |
0.7 | Intermediate Similarity | NPC321956 |
0.7 | Intermediate Similarity | NPC291847 |
0.7 | Intermediate Similarity | NPC473993 |
0.7 | Intermediate Similarity | NPC469386 |
0.6993 | Remote Similarity | NPC160692 |
0.6993 | Remote Similarity | NPC76213 |
0.6993 | Remote Similarity | NPC277669 |
0.6992 | Remote Similarity | NPC303611 |
0.6992 | Remote Similarity | NPC290515 |
0.6992 | Remote Similarity | NPC226096 |
0.6992 | Remote Similarity | NPC108606 |
0.6992 | Remote Similarity | NPC164514 |
0.6985 | Remote Similarity | NPC198734 |
0.6985 | Remote Similarity | NPC83279 |
0.6985 | Remote Similarity | NPC269242 |
0.6985 | Remote Similarity | NPC469412 |
0.6978 | Remote Similarity | NPC194519 |
0.6978 | Remote Similarity | NPC207179 |
0.6978 | Remote Similarity | NPC167571 |
0.6978 | Remote Similarity | NPC470510 |
0.6978 | Remote Similarity | NPC278552 |
0.6974 | Remote Similarity | NPC207824 |
0.6974 | Remote Similarity | NPC60538 |
0.697 | Remote Similarity | NPC470837 |
0.6966 | Remote Similarity | NPC470249 |
0.6963 | Remote Similarity | NPC43275 |
0.6963 | Remote Similarity | NPC135961 |
0.6963 | Remote Similarity | NPC311595 |
0.6963 | Remote Similarity | NPC32152 |
0.6963 | Remote Similarity | NPC24474 |
0.696 | Remote Similarity | NPC84325 |
0.6957 | Remote Similarity | NPC307020 |
0.6953 | Remote Similarity | NPC227894 |
0.695 | Remote Similarity | NPC222572 |
0.695 | Remote Similarity | NPC87224 |
0.6947 | Remote Similarity | NPC474920 |
0.6947 | Remote Similarity | NPC266116 |
0.694 | Remote Similarity | NPC323948 |
0.6934 | Remote Similarity | NPC470804 |
0.6929 | Remote Similarity | NPC58607 |
0.6929 | Remote Similarity | NPC227255 |
0.6929 | Remote Similarity | NPC178284 |
0.6929 | Remote Similarity | NPC191037 |
0.6928 | Remote Similarity | NPC469711 |
0.6923 | Remote Similarity | NPC88868 |
0.6923 | Remote Similarity | NPC103799 |
0.6923 | Remote Similarity | NPC231251 |
0.6923 | Remote Similarity | NPC25067 |
0.6923 | Remote Similarity | NPC118419 |
0.6918 | Remote Similarity | NPC14600 |
0.6918 | Remote Similarity | NPC312770 |
0.6918 | Remote Similarity | NPC204848 |
0.6918 | Remote Similarity | NPC193528 |
0.6918 | Remote Similarity | NPC160607 |
0.6918 | Remote Similarity | NPC41473 |
0.6917 | Remote Similarity | NPC101139 |
0.6917 | Remote Similarity | NPC303370 |
0.6917 | Remote Similarity | NPC71853 |
0.6917 | Remote Similarity | NPC301321 |
0.6912 | Remote Similarity | NPC471308 |
0.6912 | Remote Similarity | NPC193193 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC136112 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
1.0 | High Similarity | NPD1794 | Approved |
0.9667 | High Similarity | NPD1818 | Approved |
0.9667 | High Similarity | NPD1819 | Approved |
0.9667 | High Similarity | NPD1820 | Approved |
0.9667 | High Similarity | NPD1817 | Approved |
0.936 | High Similarity | NPD3162 | Approved |
0.936 | High Similarity | NPD3163 | Approved |
0.9355 | High Similarity | NPD3165 | Approved |
0.9355 | High Similarity | NPD3166 | Approved |
0.9355 | High Similarity | NPD3164 | Approved |
0.9355 | High Similarity | NPD3167 | Approved |
0.9286 | High Similarity | NPD3597 | Clinical (unspecified phase) |
0.9206 | High Similarity | NPD1423 | Approved |
0.92 | High Similarity | NPD3179 | Approved |
0.92 | High Similarity | NPD3180 | Approved |
0.9147 | High Similarity | NPD2155 | Approved |
0.9147 | High Similarity | NPD2154 | Approved |
0.9147 | High Similarity | NPD2156 | Approved |
0.8788 | High Similarity | NPD2239 | Approved |
0.8788 | High Similarity | NPD2240 | Approved |
0.877 | High Similarity | NPD1797 | Approved |
0.877 | High Similarity | NPD1798 | Approved |
0.873 | High Similarity | NPD1770 | Clinical (unspecified phase) |
0.8682 | High Similarity | NPD3056 | Clinical (unspecified phase) |
0.8647 | High Similarity | NPD3175 | Clinical (unspecified phase) |
0.8613 | High Similarity | NPD1774 | Approved |
0.8603 | High Similarity | NPD2677 | Approved |
0.8603 | High Similarity | NPD5160 | Discontinued |
0.8548 | High Similarity | NPD2554 | Approved |
0.8548 | High Similarity | NPD2556 | Approved |
0.8538 | High Similarity | NPD1336 | Approved |
0.8456 | Intermediate Similarity | NPD5062 | Approved |
0.8456 | Intermediate Similarity | NPD5061 | Approved |
0.8421 | Intermediate Similarity | NPD3052 | Approved |
0.8421 | Intermediate Similarity | NPD3054 | Approved |
0.8361 | Intermediate Similarity | NPD593 | Approved |
0.8361 | Intermediate Similarity | NPD595 | Approved |
0.8357 | Intermediate Similarity | NPD2675 | Approved |
0.8357 | Intermediate Similarity | NPD2676 | Approved |
0.8333 | Intermediate Similarity | NPD3531 | Approved |
0.8333 | Intermediate Similarity | NPD3532 | Approved |
0.8333 | Intermediate Similarity | NPD3530 | Approved |
0.8321 | Intermediate Similarity | NPD4162 | Approved |
0.832 | Intermediate Similarity | NPD3049 | Approved |
0.8286 | Intermediate Similarity | NPD4661 | Approved |
0.8286 | Intermediate Similarity | NPD4662 | Approved |
0.8279 | Intermediate Similarity | NPD594 | Approved |
0.8279 | Intermediate Similarity | NPD592 | Approved |
0.8209 | Intermediate Similarity | NPD1341 | Clinical (unspecified phase) |
0.8188 | Intermediate Similarity | NPD1416 | Approved |
0.8182 | Intermediate Similarity | NPD2651 | Approved |
0.8182 | Intermediate Similarity | NPD2649 | Approved |
0.8168 | Intermediate Similarity | NPD2250 | Discontinued |
0.8156 | Intermediate Similarity | NPD3536 | Discontinued |
0.8156 | Intermediate Similarity | NPD3985 | Discontinued |
0.8116 | Intermediate Similarity | NPD1372 | Clinical (unspecified phase) |
0.8099 | Intermediate Similarity | NPD2236 | Approved |
0.8083 | Intermediate Similarity | NPD290 | Approved |
0.8045 | Intermediate Similarity | NPD6179 | Discontinued |
0.8045 | Intermediate Similarity | NPD5163 | Phase 2 |
0.8016 | Intermediate Similarity | NPD1103 | Approved |
0.8016 | Intermediate Similarity | NPD1102 | Approved |
0.8014 | Intermediate Similarity | NPD3122 | Phase 3 |
0.8 | Intermediate Similarity | NPD2428 | Approved |
0.8 | Intermediate Similarity | NPD2429 | Approved |
0.8 | Intermediate Similarity | NPD2557 | Approved |
0.7945 | Intermediate Similarity | NPD6677 | Suspended |
0.7923 | Intermediate Similarity | NPD2235 | Phase 2 |
0.7923 | Intermediate Similarity | NPD2231 | Phase 2 |
0.7902 | Intermediate Similarity | NPD6419 | Discontinued |
0.7895 | Intermediate Similarity | NPD5266 | Clinical (unspecified phase) |
0.7869 | Intermediate Similarity | NPD2684 | Approved |
0.7836 | Intermediate Similarity | NPD596 | Approved |
0.7836 | Intermediate Similarity | NPD600 | Approved |
0.7795 | Intermediate Similarity | NPD3596 | Phase 2 |
0.7734 | Intermediate Similarity | NPD317 | Approved |
0.7734 | Intermediate Similarity | NPD16 | Approved |
0.7734 | Intermediate Similarity | NPD318 | Approved |
0.7734 | Intermediate Similarity | NPD856 | Approved |
0.7718 | Intermediate Similarity | NPD3465 | Clinical (unspecified phase) |
0.7714 | Intermediate Similarity | NPD6032 | Approved |
0.7697 | Intermediate Similarity | NPD4666 | Phase 3 |
0.7687 | Intermediate Similarity | NPD558 | Phase 2 |
0.7687 | Intermediate Similarity | NPD3691 | Phase 2 |
0.7687 | Intermediate Similarity | NPD3690 | Phase 2 |
0.7676 | Intermediate Similarity | NPD2460 | Phase 3 |
0.7676 | Intermediate Similarity | NPD2459 | Approved |
0.7676 | Intermediate Similarity | NPD2458 | Approved |
0.7676 | Intermediate Similarity | NPD3060 | Approved |
0.7676 | Intermediate Similarity | NPD2976 | Clinical (unspecified phase) |
0.7664 | Intermediate Similarity | NPD5745 | Approved |
0.7652 | Intermediate Similarity | NPD2562 | Approved |
0.7652 | Intermediate Similarity | NPD2561 | Approved |
0.7651 | Intermediate Similarity | NPD5722 | Discontinued |
0.7651 | Intermediate Similarity | NPD4018 | Clinical (unspecified phase) |
0.7643 | Intermediate Similarity | NPD2661 | Clinical (unspecified phase) |
0.7643 | Intermediate Similarity | NPD3152 | Clinical (unspecified phase) |
0.7632 | Intermediate Similarity | NPD5709 | Phase 3 |
0.7619 | Intermediate Similarity | NPD7843 | Approved |
0.7615 | Intermediate Similarity | NPD3443 | Approved |
0.7615 | Intermediate Similarity | NPD3444 | Approved |
0.7615 | Intermediate Similarity | NPD3445 | Approved |
0.7612 | Intermediate Similarity | NPD1134 | Approved |
0.7612 | Intermediate Similarity | NPD1135 | Approved |
0.7612 | Intermediate Similarity | NPD1133 | Approved |
0.7612 | Intermediate Similarity | NPD1131 | Approved |
0.7612 | Intermediate Similarity | NPD1129 | Approved |
0.7594 | Intermediate Similarity | NPD6582 | Phase 2 |
0.7594 | Intermediate Similarity | NPD3685 | Discontinued |
0.7594 | Intermediate Similarity | NPD6583 | Phase 3 |
0.7589 | Intermediate Similarity | NPD1422 | Approved |
0.7586 | Intermediate Similarity | NPD6087 | Phase 1 |
0.7552 | Intermediate Similarity | NPD4236 | Phase 3 |
0.7552 | Intermediate Similarity | NPD4237 | Approved |
0.7548 | Intermediate Similarity | NPD2216 | Approved |
0.7548 | Intermediate Similarity | NPD2215 | Approved |
0.7538 | Intermediate Similarity | NPD6581 | Approved |
0.7538 | Intermediate Similarity | NPD2486 | Discontinued |
0.7538 | Intermediate Similarity | NPD316 | Approved |
0.7538 | Intermediate Similarity | NPD6580 | Approved |
0.7536 | Intermediate Similarity | NPD2245 | Discovery |
0.7534 | Intermediate Similarity | NPD1754 | Clinical (unspecified phase) |
0.752 | Intermediate Similarity | NPD550 | Approved |
0.752 | Intermediate Similarity | NPD551 | Approved |
0.7518 | Intermediate Similarity | NPD5746 | Approved |
0.7516 | Intermediate Similarity | NPD2163 | Approved |
0.7516 | Intermediate Similarity | NPD6315 | Phase 2 |
0.75 | Intermediate Similarity | NPD3687 | Approved |
0.75 | Intermediate Similarity | NPD4581 | Clinical (unspecified phase) |
0.75 | Intermediate Similarity | NPD155 | Clinical (unspecified phase) |
0.75 | Intermediate Similarity | NPD5373 | Approved |
0.75 | Intermediate Similarity | NPD5374 | Approved |
0.75 | Intermediate Similarity | NPD3686 | Approved |
0.7483 | Intermediate Similarity | NPD52 | Approved |
0.7483 | Intermediate Similarity | NPD7526 | Approved |
0.7483 | Intermediate Similarity | NPD7527 | Clinical (unspecified phase) |
0.7481 | Intermediate Similarity | NPD6830 | Clinical (unspecified phase) |
0.7481 | Intermediate Similarity | NPD2595 | Approved |
0.7481 | Intermediate Similarity | NPD2594 | Approved |
0.748 | Intermediate Similarity | NPD821 | Approved |
0.7464 | Intermediate Similarity | NPD601 | Approved |
0.7464 | Intermediate Similarity | NPD597 | Approved |
0.7464 | Intermediate Similarity | NPD598 | Approved |
0.7464 | Intermediate Similarity | NPD3374 | Clinical (unspecified phase) |
0.7464 | Intermediate Similarity | NPD1048 | Approved |
0.7462 | Intermediate Similarity | NPD9613 | Approved |
0.7462 | Intermediate Similarity | NPD9616 | Approved |
0.7462 | Intermediate Similarity | NPD9615 | Approved |
0.7452 | Intermediate Similarity | NPD5880 | Clinical (unspecified phase) |
0.7447 | Intermediate Similarity | NPD2200 | Suspended |
0.7444 | Intermediate Similarity | NPD776 | Approved |
0.7442 | Intermediate Similarity | NPD7157 | Approved |
0.7432 | Intermediate Similarity | NPD5976 | Discontinued |
0.7426 | Intermediate Similarity | NPD6584 | Phase 3 |
0.7415 | Intermediate Similarity | NPD1771 | Clinical (unspecified phase) |
0.7415 | Intermediate Similarity | NPD2874 | Phase 2 |
0.741 | Intermediate Similarity | NPD1130 | Approved |
0.741 | Intermediate Similarity | NPD1132 | Approved |
0.741 | Intermediate Similarity | NPD839 | Approved |
0.741 | Intermediate Similarity | NPD840 | Approved |
0.741 | Intermediate Similarity | NPD1136 | Approved |
0.7405 | Intermediate Similarity | NPD6620 | Discovery |
0.7398 | Intermediate Similarity | NPD315 | Approved |
0.7398 | Intermediate Similarity | NPD314 | Approved |
0.7398 | Intermediate Similarity | NPD311 | Approved |
0.7398 | Intermediate Similarity | NPD309 | Approved |
0.7398 | Intermediate Similarity | NPD310 | Approved |
0.7398 | Intermediate Similarity | NPD10 | Approved |
0.7389 | Intermediate Similarity | NPD4575 | Clinical (unspecified phase) |
0.7376 | Intermediate Similarity | NPD2224 | Approved |
0.7376 | Intermediate Similarity | NPD2223 | Approved |
0.7372 | Intermediate Similarity | NPD455 | Discontinued |
0.7368 | Intermediate Similarity | NPD3294 | Phase 2 |
0.7368 | Intermediate Similarity | NPD2978 | Approved |
0.7368 | Intermediate Similarity | NPD2977 | Approved |
0.7361 | Intermediate Similarity | NPD1391 | Approved |
0.7353 | Intermediate Similarity | NPD4098 | Discontinued |
0.7351 | Intermediate Similarity | NPD6072 | Discontinued |
0.7348 | Intermediate Similarity | NPD6382 | Discontinued |
0.7343 | Intermediate Similarity | NPD3156 | Discontinued |
0.7333 | Intermediate Similarity | NPD6543 | Approved |
0.7333 | Intermediate Similarity | NPD6542 | Approved |
0.7333 | Intermediate Similarity | NPD6540 | Phase 3 |
0.7333 | Intermediate Similarity | NPD6539 | Approved |
0.7329 | Intermediate Similarity | NPD3692 | Discontinued |
0.7324 | Intermediate Similarity | NPD5688 | Approved |
0.7324 | Intermediate Similarity | NPD5689 | Approved |
0.7323 | Intermediate Similarity | NPD2673 | Approved |
0.7323 | Intermediate Similarity | NPD2671 | Approved |
0.7319 | Intermediate Similarity | NPD5752 | Clinical (unspecified phase) |
0.7319 | Intermediate Similarity | NPD3537 | Clinical (unspecified phase) |
0.7303 | Intermediate Similarity | NPD1769 | Discontinued |
0.7299 | Intermediate Similarity | NPD599 | Approved |
0.7299 | Intermediate Similarity | NPD602 | Approved |
0.7299 | Intermediate Similarity | NPD2987 | Approved |
0.7299 | Intermediate Similarity | NPD7018 | Phase 2 |
0.7299 | Intermediate Similarity | NPD2990 | Approved |
0.7297 | Intermediate Similarity | NPD2504 | Approved |
0.7297 | Intermediate Similarity | NPD2505 | Approved |
0.7293 | Intermediate Similarity | NPD2667 | Approved |
PubChem CID   | 203685 |
ChEMBL   | CHEMBL1395661 |
ZINC   |
Molecular Weight:   | 249.17 |
ALogP:   | 0.0189 |
MLogP:   | 2.78 |
XLogP:   | 3.272 |
# Rotatable Bonds:   | 11 |
Polar Surface Area:   | 41.49 |
# H-Bond Aceptor:   | 2 |
# H-Bond Donor:   | 2 |
# Rings:   | 1 |
# Heavy Atoms:   | 18 |