Natural Product: NPC216810

Natural Product ID:  NPC216810
Common Name:   Linderalactone
IUPAC Name:  
Synonyms:   Linderalactone
Molecular Formula:   C15H16O3
Standard InCHIKey:  LWCKQMHMTSRRAA-QGQQYVBWSA-N
Standard InCHI:  InChI=1S/C15H16O3/c1-9-4-3-5-11-7-13(18-15(11)16)14-10(2)8-17-12(14)6-9/h4,7-8,13H,3,5-6H2,1-2H3/b9-4+/t13-/m1/s1
Canonical SMILES:  C/C/1=CCCC2=C[C@H](c3c(C1)occ3C)OC2=O
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO23883 Penicillium abidjanum Species Aspergillaceae Eukaryota UNPD*
NPO9363 Ferula ammoniacum Species Apiaceae Eukaryota UNPD*
NPO1116 Periconia atropurpurea Species Periconiaceae Eukaryota UNPD*
NPO9606 Castanea dentata Species Fagaceae Eukaryota UNPD*
NPO11527 Ibacus peronii Species Scyllaridae Eukaryota UNPD*
NPO5714 Rogeria adenophylla Species Pedaliaceae Eukaryota UNPD*
NPO2996 Pistacia atlantica Species Anacardiaceae Eukaryota UNPD*
NPO10530 Aconitum subcuneatum Species Ranunculaceae Eukaryota UNPD*
NPO6696 Chukrasia tabularis Species Meliaceae Eukaryota UNPD*
NPO12853 Leucocarpus perfoliatus Species Phrymaceae Eukaryota UNPD*
NPO15351 Streptomyces prunicolor Species Streptomycetaceae Bacteria UNPD*
NPO2207 Sphaerella rubella NA NA NA UNPD*
NPO12146 Stemodia maritima Species Plantaginaceae Eukaryota UNPD*
NPO4682 Lindera aggregata Species Lauraceae Eukaryota TCMID*
NPO12553 Lindera chunii Species Lauraceae Eukaryota TCMID*
NPO12633 Rapanea neurophylla Species Primulaceae Eukaryota UNPD*
NPO11206 Trifolium hybridum Species Fabaceae Eukaryota UNPD*
NPO1044 Caiman crocodilus Species Alligatoridae Eukaryota UNPD*
NPO4228 Wickerhamomyces anomalus Species Phaffomycetaceae Eukaryota UNPD*
NPO12553 Lindera chunii Species Lauraceae Eukaryota HerDing*
NPO23270 Neolitsea daibuensis Species Lauraceae Eukaryota Root PMID[22148193]
NPO31274 Lindera strychnifolia Species Tineidae Eukaryota HerDing*
NPO11898 Lobophora variegata Species Dictyotaceae Eukaryota UNPD*
NPO6541 Scrophularia buergeriana Species Scrophulariaceae Eukaryota UNPD*
NPO5247 Elaphoglossum lindbergii Species Dryopteridaceae Eukaryota UNPD*
NPO11093 Pseudobersama mossambicensis Species Meliaceae Eukaryota UNPD*
NPO7560 Tachardia acaciae NA NA NA UNPD*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT65 Cell Line HepG2 Homo sapiens EC50 = 98000 nM 19639966
NPT2 Others Unspecified IC50 = 8.48 ug/ml 22148193
NPT2 Others Unspecified IC50 = 3.21 ug/ml 22148193

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC216810 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.9147 High Similarity NPC286130
0.9076 High Similarity NPC227660
0.8828 High Similarity NPC136340
0.8814 High Similarity NPC22678
0.8593 High Similarity NPC248795
0.8561 High Similarity NPC159786
0.8516 High Similarity NPC184391
0.848 Intermediate Similarity NPC1848
0.8444 Intermediate Similarity NPC474615
0.8372 Intermediate Similarity NPC319140
0.8372 Intermediate Similarity NPC95567
0.832 Intermediate Similarity NPC67345
0.832 Intermediate Similarity NPC244862
0.8293 Intermediate Similarity NPC205523
0.8273 Intermediate Similarity NPC84479
0.8209 Intermediate Similarity NPC200718
0.8209 Intermediate Similarity NPC106247
0.8182 Intermediate Similarity NPC21460
0.8182 Intermediate Similarity NPC45947
0.8175 Intermediate Similarity NPC473969
0.816 Intermediate Similarity NPC217180
0.816 Intermediate Similarity NPC312525
0.816 Intermediate Similarity NPC131801
0.814 Intermediate Similarity NPC188377
0.814 Intermediate Similarity NPC65735
0.8125 Intermediate Similarity NPC270807
0.8125 Intermediate Similarity NPC323118
0.8125 Intermediate Similarity NPC174915
0.8115 Intermediate Similarity NPC105249
0.8102 Intermediate Similarity NPC472376
0.8095 Intermediate Similarity NPC187547
0.8095 Intermediate Similarity NPC21831
0.8085 Intermediate Similarity NPC195920
0.8071 Intermediate Similarity NPC254198
0.8071 Intermediate Similarity NPC205071
0.8065 Intermediate Similarity NPC292036
0.8031 Intermediate Similarity NPC4898
0.8029 Intermediate Similarity NPC473268
0.8028 Intermediate Similarity NPC62799
0.8015 Intermediate Similarity NPC92941
0.8 Intermediate Similarity NPC118853
0.7986 Intermediate Similarity NPC282973
0.7985 Intermediate Similarity NPC475092
0.7984 Intermediate Similarity NPC263870
0.7958 Intermediate Similarity NPC37488
0.7943 Intermediate Similarity NPC110305
0.7937 Intermediate Similarity NPC79202
0.7937 Intermediate Similarity NPC45536
0.7937 Intermediate Similarity NPC59035
0.7917 Intermediate Similarity NPC19747
0.7914 Intermediate Similarity NPC107571
0.7907 Intermediate Similarity NPC97566
0.7902 Intermediate Similarity NPC475864
0.7902 Intermediate Similarity NPC104924
0.7899 Intermediate Similarity NPC470742
0.7879 Intermediate Similarity NPC474260
0.7879 Intermediate Similarity NPC81912
0.7879 Intermediate Similarity NPC329922
0.7879 Intermediate Similarity NPC329694
0.7863 Intermediate Similarity NPC243269
0.7862 Intermediate Similarity NPC474270
0.7862 Intermediate Similarity NPC475904
0.7862 Intermediate Similarity NPC211625
0.7857 Intermediate Similarity NPC28054
0.7847 Intermediate Similarity NPC308799
0.7842 Intermediate Similarity NPC220094
0.7842 Intermediate Similarity NPC476943
0.782 Intermediate Similarity NPC141059
0.7803 Intermediate Similarity NPC473885
0.7803 Intermediate Similarity NPC471074
0.7803 Intermediate Similarity NPC75557
0.7803 Intermediate Similarity NPC71274
0.7795 Intermediate Similarity NPC476014
0.7795 Intermediate Similarity NPC476031
0.7793 Intermediate Similarity NPC113428
0.7793 Intermediate Similarity NPC474255
0.7793 Intermediate Similarity NPC474220
0.7793 Intermediate Similarity NPC61284
0.7793 Intermediate Similarity NPC471618
0.7786 Intermediate Similarity NPC475818
0.7786 Intermediate Similarity NPC476351
0.777 Intermediate Similarity NPC310830
0.777 Intermediate Similarity NPC186626
0.777 Intermediate Similarity NPC215109
0.777 Intermediate Similarity NPC170604
0.7769 Intermediate Similarity NPC79557
0.7761 Intermediate Similarity NPC329707
0.7752 Intermediate Similarity NPC137710
0.7744 Intermediate Similarity NPC83301
0.7737 Intermediate Similarity NPC474425
0.7737 Intermediate Similarity NPC474426
0.7737 Intermediate Similarity NPC474407
0.7737 Intermediate Similarity NPC470740
0.7737 Intermediate Similarity NPC293253
0.7734 Intermediate Similarity NPC144745
0.7734 Intermediate Similarity NPC217423
0.7734 Intermediate Similarity NPC208906
0.7724 Intermediate Similarity NPC471521
0.7724 Intermediate Similarity NPC474317
0.7724 Intermediate Similarity NPC473356
0.7717 Intermediate Similarity NPC11821
0.771 Intermediate Similarity NPC283284
0.771 Intermediate Similarity NPC289911
0.7705 Intermediate Similarity NPC42471
0.7698 Intermediate Similarity NPC146872
0.7698 Intermediate Similarity NPC303217
0.7692 Intermediate Similarity NPC230951
0.7692 Intermediate Similarity NPC22248
0.7692 Intermediate Similarity NPC267632
0.7692 Intermediate Similarity NPC223415
0.7687 Intermediate Similarity NPC476016
0.7687 Intermediate Similarity NPC137570
0.7669 Intermediate Similarity NPC474829
0.7656 Intermediate Similarity NPC76844
0.7651 Intermediate Similarity NPC114880
0.7647 Intermediate Similarity NPC66246
0.7647 Intermediate Similarity NPC170546
0.7643 Intermediate Similarity NPC307401
0.7639 Intermediate Similarity NPC307346
0.7639 Intermediate Similarity NPC261733
0.7639 Intermediate Similarity NPC267004
0.7639 Intermediate Similarity NPC218712
0.7634 Intermediate Similarity NPC474136
0.763 Intermediate Similarity NPC474438
0.763 Intermediate Similarity NPC474279
0.7606 Intermediate Similarity NPC218204
0.7606 Intermediate Similarity NPC473681
0.7606 Intermediate Similarity NPC61157
0.7603 Intermediate Similarity NPC224418
0.76 Intermediate Similarity NPC75310
0.7594 Intermediate Similarity NPC178382
0.7591 Intermediate Similarity NPC282230
0.7591 Intermediate Similarity NPC183348
0.7591 Intermediate Similarity NPC298190
0.7591 Intermediate Similarity NPC477645
0.7589 Intermediate Similarity NPC236532
0.7586 Intermediate Similarity NPC56731
0.7584 Intermediate Similarity NPC474219
0.7584 Intermediate Similarity NPC474378
0.7578 Intermediate Similarity NPC188907
0.7574 Intermediate Similarity NPC59502
0.7569 Intermediate Similarity NPC64568
0.7569 Intermediate Similarity NPC470741
0.7557 Intermediate Similarity NPC474817
0.7556 Intermediate Similarity NPC474830
0.7552 Intermediate Similarity NPC20500
0.7538 Intermediate Similarity NPC243704
0.7538 Intermediate Similarity NPC206007
0.7538 Intermediate Similarity NPC291619
0.7538 Intermediate Similarity NPC254958
0.7537 Intermediate Similarity NPC471559
0.7536 Intermediate Similarity NPC470977
0.7536 Intermediate Similarity NPC196979
0.7536 Intermediate Similarity NPC15083
0.7536 Intermediate Similarity NPC470976
0.7536 Intermediate Similarity NPC471817
0.7536 Intermediate Similarity NPC473982
0.7535 Intermediate Similarity NPC202260
0.7535 Intermediate Similarity NPC474722
0.7519 Intermediate Similarity NPC16922
0.7517 Intermediate Similarity NPC191104
0.7517 Intermediate Similarity NPC142113
0.75 Intermediate Similarity NPC329180
0.75 Intermediate Similarity NPC115859
0.75 Intermediate Similarity NPC470856
0.7483 Intermediate Similarity NPC18904
0.7482 Intermediate Similarity NPC214097
0.748 Intermediate Similarity NPC1811
0.748 Intermediate Similarity NPC26157
0.7467 Intermediate Similarity NPC475777
0.7465 Intermediate Similarity NPC177262
0.7464 Intermediate Similarity NPC17681
0.7462 Intermediate Similarity NPC45104
0.7451 Intermediate Similarity NPC474611
0.745 Intermediate Similarity NPC88445
0.7442 Intermediate Similarity NPC150895
0.7438 Intermediate Similarity NPC156768
0.7434 Intermediate Similarity NPC474542
0.7432 Intermediate Similarity NPC74539
0.7432 Intermediate Similarity NPC93666
0.7432 Intermediate Similarity NPC304443
0.7426 Intermediate Similarity NPC471554
0.7426 Intermediate Similarity NPC473355
0.7426 Intermediate Similarity NPC471573
0.7426 Intermediate Similarity NPC471501
0.7422 Intermediate Similarity NPC53953
0.7417 Intermediate Similarity NPC24232
0.7415 Intermediate Similarity NPC246903
0.7415 Intermediate Similarity NPC208584
0.7415 Intermediate Similarity NPC262198
0.7415 Intermediate Similarity NPC346
0.7415 Intermediate Similarity NPC97904
0.7415 Intermediate Similarity NPC233763
0.741 Intermediate Similarity NPC97740
0.741 Intermediate Similarity NPC45358
0.7407 Intermediate Similarity NPC179354
0.7405 Intermediate Similarity NPC293424
0.7397 Intermediate Similarity NPC476944
0.7397 Intermediate Similarity NPC86935
0.7394 Intermediate Similarity NPC42400

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC216810 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.766 Intermediate Similarity NPD2343 Clinical (unspecified phase)
0.7556 Intermediate Similarity NPD1019 Discontinued
0.7445 Intermediate Similarity NPD6832 Phase 2
0.7432 Intermediate Similarity NPD920 Approved
0.7415 Intermediate Similarity NPD642 Clinical (unspecified phase)
0.7388 Intermediate Similarity NPD9717 Approved
0.7323 Intermediate Similarity NPD2181 Clinical (unspecified phase)
0.7313 Intermediate Similarity NPD1547 Clinical (unspecified phase)
0.729 Intermediate Similarity NPD5537 Clinical (unspecified phase)
0.7279 Intermediate Similarity NPD643 Clinical (unspecified phase)
0.7192 Intermediate Similarity NPD1243 Approved
0.7183 Intermediate Similarity NPD1899 Clinical (unspecified phase)
0.7154 Intermediate Similarity NPD1241 Discontinued
0.7101 Intermediate Similarity NPD1203 Approved
0.7092 Intermediate Similarity NPD2313 Discontinued
0.7063 Intermediate Similarity NPD447 Suspended
0.7034 Intermediate Similarity NPD2799 Discontinued
0.6992 Remote Similarity NPD9493 Approved
0.6986 Remote Similarity NPD1551 Phase 2
0.6986 Remote Similarity NPD2796 Approved
0.6944 Remote Similarity NPD1933 Approved
0.6939 Remote Similarity NPD2346 Discontinued
0.6939 Remote Similarity NPD2344 Approved
0.6939 Remote Similarity NPD1471 Phase 3
0.6899 Remote Similarity NPD2182 Approved
0.6857 Remote Similarity NPD2797 Approved
0.6857 Remote Similarity NPD3267 Approved
0.6857 Remote Similarity NPD1049 Clinical (unspecified phase)
0.6857 Remote Similarity NPD3266 Approved
0.6855 Remote Similarity NPD919 Approved
0.6853 Remote Similarity NPD411 Approved
0.6842 Remote Similarity NPD2532 Approved
0.6842 Remote Similarity NPD2534 Approved
0.6842 Remote Similarity NPD2533 Approved
0.6832 Remote Similarity NPD6808 Phase 2
0.6809 Remote Similarity NPD2798 Approved
0.6809 Remote Similarity NPD5647 Approved
0.6776 Remote Similarity NPD6799 Approved
0.6763 Remote Similarity NPD3972 Approved
0.6759 Remote Similarity NPD4307 Phase 2
0.6757 Remote Similarity NPD2935 Discontinued
0.6755 Remote Similarity NPD2309 Approved
0.6744 Remote Similarity NPD3134 Approved
0.6736 Remote Similarity NPD1699 Clinical (unspecified phase)
0.6736 Remote Similarity NPD3268 Approved
0.6731 Remote Similarity NPD6599 Discontinued
0.6719 Remote Similarity NPD164 Approved
0.6718 Remote Similarity NPD2067 Discontinued
0.6715 Remote Similarity NPD5585 Approved
0.6711 Remote Similarity NPD6002 Phase 3
0.6711 Remote Similarity NPD6005 Phase 3
0.6711 Remote Similarity NPD6003 Clinical (unspecified phase)
0.6711 Remote Similarity NPD6004 Phase 3
0.6711 Remote Similarity NPD6006 Clinical (unspecified phase)
0.6709 Remote Similarity NPD5761 Phase 2
0.6709 Remote Similarity NPD5760 Phase 2
0.6692 Remote Similarity NPD1358 Approved
0.6689 Remote Similarity NPD3748 Approved
0.6689 Remote Similarity NPD4628 Phase 3
0.6667 Remote Similarity NPD1238 Approved
0.6667 Remote Similarity NPD1549 Phase 2
0.6667 Remote Similarity NPD1247 Approved
0.6667 Remote Similarity NPD1876 Approved
0.6667 Remote Similarity NPD17 Approved
0.6646 Remote Similarity NPD6279 Approved
0.6646 Remote Similarity NPD6280 Approved
0.6645 Remote Similarity NPD5403 Approved
0.6645 Remote Similarity NPD3887 Approved
0.6642 Remote Similarity NPD9545 Approved
0.6641 Remote Similarity NPD9261 Approved
0.6623 Remote Similarity NPD7421 Clinical (unspecified phase)
0.6623 Remote Similarity NPD5401 Approved
0.6623 Remote Similarity NPD2800 Approved
0.6608 Remote Similarity NPD8434 Phase 2
0.6607 Remote Similarity NPD6559 Discontinued
0.6605 Remote Similarity NPD5494 Approved
0.6604 Remote Similarity NPD7096 Clinical (unspecified phase)
0.6604 Remote Similarity NPD7819 Suspended
0.66 Remote Similarity NPD1552 Clinical (unspecified phase)
0.66 Remote Similarity NPD1550 Clinical (unspecified phase)
0.6599 Remote Similarity NPD4618 Approved
0.6599 Remote Similarity NPD4622 Approved
0.6593 Remote Similarity NPD690 Clinical (unspecified phase)
0.6584 Remote Similarity NPD3749 Approved
0.6582 Remote Similarity NPD5890 Approved
0.6582 Remote Similarity NPD7411 Suspended
0.6582 Remote Similarity NPD5889 Approved
0.6581 Remote Similarity NPD6273 Approved
0.6579 Remote Similarity NPD1878 Clinical (unspecified phase)
0.6577 Remote Similarity NPD4308 Phase 3
0.6566 Remote Similarity NPD7893 Clinical (unspecified phase)
0.6562 Remote Similarity NPD5402 Approved
0.6541 Remote Similarity NPD6801 Discontinued
0.6538 Remote Similarity NPD9697 Approved
0.6531 Remote Similarity NPD3140 Approved
0.6531 Remote Similarity NPD3142 Approved
0.6531 Remote Similarity NPD1240 Approved
0.6525 Remote Similarity NPD1608 Approved
0.6522 Remote Similarity NPD1894 Discontinued
0.651 Remote Similarity NPD5689 Approved
0.651 Remote Similarity NPD5688 Approved
0.6503 Remote Similarity NPD6362 Approved
0.6493 Remote Similarity NPD1609 Clinical (unspecified phase)
0.6486 Remote Similarity NPD6355 Discontinued
0.6481 Remote Similarity NPD7075 Discontinued
0.6479 Remote Similarity NPD4359 Approved
0.6471 Remote Similarity NPD3750 Approved
0.6467 Remote Similarity NPD7033 Discontinued
0.6463 Remote Similarity NPD6233 Phase 2
0.646 Remote Similarity NPD5616 Clinical (unspecified phase)
0.6458 Remote Similarity NPD6007 Clinical (unspecified phase)
0.6456 Remote Similarity NPD5808 Clinical (unspecified phase)
0.6456 Remote Similarity NPD3226 Approved
0.6449 Remote Similarity NPD9092 Discovery
0.6447 Remote Similarity NPD970 Clinical (unspecified phase)
0.6443 Remote Similarity NPD1607 Approved
0.6439 Remote Similarity NPD9267 Approved
0.6439 Remote Similarity NPD9263 Approved
0.6439 Remote Similarity NPD9264 Approved
0.6429 Remote Similarity NPD1778 Approved
0.6429 Remote Similarity NPD3412 Clinical (unspecified phase)
0.6424 Remote Similarity NPD5668 Clinical (unspecified phase)
0.642 Remote Similarity NPD7768 Phase 2
0.6415 Remote Similarity NPD6585 Discontinued
0.6414 Remote Similarity NPD9494 Approved
0.6412 Remote Similarity NPD6764 Approved
0.6412 Remote Similarity NPD6765 Approved
0.641 Remote Similarity NPD4662 Approved
0.641 Remote Similarity NPD4378 Clinical (unspecified phase)
0.641 Remote Similarity NPD4661 Approved
0.6395 Remote Similarity NPD6798 Discontinued
0.6395 Remote Similarity NPD6859 Clinical (unspecified phase)
0.6391 Remote Similarity NPD74 Approved
0.6391 Remote Similarity NPD9266 Approved
0.6386 Remote Similarity NPD3926 Phase 2
0.6383 Remote Similarity NPD3496 Discontinued
0.6382 Remote Similarity NPD2355 Clinical (unspecified phase)
0.6382 Remote Similarity NPD2353 Approved
0.6376 Remote Similarity NPD230 Phase 1
0.6358 Remote Similarity NPD1510 Phase 2
0.6358 Remote Similarity NPD3817 Phase 2
0.6357 Remote Similarity NPD5691 Approved
0.6351 Remote Similarity NPD8032 Phase 2
0.6338 Remote Similarity NPD1281 Approved
0.6333 Remote Similarity NPD6653 Approved
0.6329 Remote Similarity NPD3873 Phase 3
0.6329 Remote Similarity NPD3869 Phase 3
0.6329 Remote Similarity NPD6980 Clinical (unspecified phase)
0.6327 Remote Similarity NPD2598 Clinical (unspecified phase)
0.6324 Remote Similarity NPD5535 Approved
0.6319 Remote Similarity NPD3882 Suspended
0.6319 Remote Similarity NPD4868 Clinical (unspecified phase)
0.6309 Remote Similarity NPD2979 Phase 3
0.6306 Remote Similarity NPD7410 Clinical (unspecified phase)
0.6299 Remote Similarity NPD2654 Approved
0.6296 Remote Similarity NPD2393 Clinical (unspecified phase)
0.6294 Remote Similarity NPD1481 Phase 2
0.6284 Remote Similarity NPD3764 Approved
0.6284 Remote Similarity NPD1296 Phase 2
0.6282 Remote Similarity NPD7440 Discontinued
0.628 Remote Similarity NPD4381 Clinical (unspecified phase)
0.6272 Remote Similarity NPD3818 Discontinued
0.6264 Remote Similarity NPD6785 Approved
0.6264 Remote Similarity NPD6784 Approved
0.6258 Remote Similarity NPD6398 Clinical (unspecified phase)
0.6258 Remote Similarity NPD8443 Clinical (unspecified phase)
0.6258 Remote Similarity NPD2296 Approved
0.625 Remote Similarity NPD7852 Clinical (unspecified phase)
0.6242 Remote Similarity NPD4870 Approved
0.6242 Remote Similarity NPD4062 Phase 3
0.6241 Remote Similarity NPD1651 Approved
0.6235 Remote Similarity NPD6844 Discontinued
0.6235 Remote Similarity NPD1934 Approved
0.6234 Remote Similarity NPD2897 Discontinued
0.6234 Remote Similarity NPD2424 Discontinued
0.6228 Remote Similarity NPD5711 Approved
0.6228 Remote Similarity NPD5710 Approved
0.6224 Remote Similarity NPD1535 Discovery
0.6218 Remote Similarity NPD3295 Clinical (unspecified phase)
0.6218 Remote Similarity NPD2354 Approved
0.6211 Remote Similarity NPD4380 Phase 2
0.6209 Remote Similarity NPD4476 Approved
0.6209 Remote Similarity NPD4477 Approved
0.6209 Remote Similarity NPD2438 Suspended
0.6207 Remote Similarity NPD3225 Approved
0.6207 Remote Similarity NPD1283 Approved
0.6203 Remote Similarity NPD7004 Clinical (unspecified phase)
0.6194 Remote Similarity NPD290 Approved
0.619 Remote Similarity NPD454 Approved
0.6184 Remote Similarity NPD2569 Approved
0.6184 Remote Similarity NPD2567 Approved
0.6164 Remote Similarity NPD5049 Phase 3
0.6164 Remote Similarity NPD2186 Approved
0.6159 Remote Similarity NPD5353 Approved
0.6154 Remote Similarity NPD7003 Approved
0.6154 Remote Similarity NPD4109 Clinical (unspecified phase)
0.6154 Remote Similarity NPD7784 Clinical (unspecified phase)
0.6154 Remote Similarity NPD4110 Phase 3
0.6149 Remote Similarity NPD2651 Approved
0.6149 Remote Similarity NPD2649 Approved

Structure

External Identifiers

PubChem CID   6450191
ChEMBL   CHEMBL1080239
ZINC  

Physicochemical Properties

Molecular Weight:  244.11
ALogP:  2.172
MLogP:  2.78
XLogP:  2.295
# Rotatable Bonds:  2
Polar Surface Area:  39.44
# H-Bond Aceptor:  2
# H-Bond Donor:  0
# Rings:  3
# Heavy Atoms:  18

Download Data

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Biological Activities  
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