GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0042221 |
response to chemical
|
ADRA1A, ADRA2A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCHE, BCL2, CA2, CA9, CDK6, CES1, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GSK3B, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IDO1, IGF1R, INSR, KCNH2, KDR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PTGS2, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TYR |
19.9271 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA12, CA2, CA7, CDK6, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GPR35, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR4, HTR7, INSR, KCNH2, KDR, MET, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
18.2542 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AR, AXL, BCHE, BCL2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, GSK3B, HSD11B2, HSD17B2, HTR1B, HTR5A, IDO1, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PTGS2, RORC, SLC6A4, SRC, TEK, TYR |
17.7635 |
[BP] GO:0010033 |
response to organic substance
|
ADRA1A, ADRA2A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCHE, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GSK3B, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR5A, IDO1, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PPARA, PTGS2, RORC, SLC6A4, SMAD3, SRC, TEK, TYR |
17.0743 |
[BP] GO:0007210 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
15.3009 |
[BP] GO:0098664 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
15.3009 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, APP, AR, BCHE, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, IDO1, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PGR, PIM1, PTGS1, PTGS2, SLC6A4, SMAD3, SRC, TEK, TERT, XDH |
15.1364 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
15.0383 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
14.9902 |
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, AR, BCHE, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FLT3, HSD11B2, HTR1B, HTR5A, NR3C1, PTGS2, RORC, SLC6A4, SRC, TEK, TYR |
14.923 |
[BP] GO:0042493 |
response to drug
|
ADRA1A, AKR1B1, APEX1, AXL, BCHE, BCL2, CA9, CDK6, CNR1, CNR2, CYP1A1, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, FABP3, HSD11B2, HTR1B, HTR2A, HTR2B, HTR2C, KCNH2, KDR, NR3C1, PTGS2, SLC6A2, SLC6A4, SRC |
13.8195 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA2, CA6, CA9, CDK6, CES1, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, GSK3B, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IDO1, IGF1R, INSR, KCNH2, KDR, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TOP2A, TYR |
13.3265 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.165 |
[BP] GO:0033993 |
response to lipid
|
ALPL, AR, AXL, BCHE, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, HTR1B, HTR5A, IDO1, NR3C1, PTGS2, RORC, SLC6A4, SRC, TYR |
13.15 |
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRA1A, ADRA2A, AKR1B1, ALPL, APEX1, APP, AR, BCHE, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DRD1, EGFR, ESR1, ESRRA, FABP3, FLT3, GSK3B, HSD11B2, HTR1B, HTR5A, IGF1R, INSR, MMP2, NR3C1, PPARA, PTGS2, SLC6A4, SMAD3, SRC, TEK |
13.138 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GPR35, GSK3B, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
13.0239 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCHE, BCL2, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR7, IDO1, IGF1R, INSR, KCNH2, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PTGS2, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TNKS2, TYR |
12.3297 |
[BP] GO:0009725 |
response to hormone
|
ADRA1A, ADRA2A, AKR1B1, ALPL, APEX1, AR, BCHE, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HTR1B, HTR5A, INSR, NR3C1, PPARA, PTGS2, SLC6A4, SRC, TEK |
12.2729 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCHE, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GSK3B, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.1286 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCHE, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GSK3B, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.9015 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESRRA, F10, F3, FABP4, FLT3, GPR35, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IDO1, INSR, KDR, MET, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.5699 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
11.5699 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
11.5313 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CBR1, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2 |
11.5294 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CES1, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, FABP3, FUT7, GBA2, GLO1, HSPA1A, HTR2B, HTR2C, IDO1, PIK3CA, PIM1, PPARA, PTGS1, PTGS2, TYR, XDH |
11.5093 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GPR35, GSK3B, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
11.4903 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DHFR |
11.4606 |
[BP] GO:0007187 |
None
|
ADORA1, ADRA1A, ADRA2A, CNR1, CNR2, DRD1, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR4, HTR5A, HTR6, HTR7 |
11.2908 |
[BP] GO:0003018 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SLC6A4, SRC, TEK |
11.1156 |
[BP] GO:0097756 |
None
|
ADORA1, ADRA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SLC6A4 |
11.1156 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GSK3B, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IDO1, IGF1R, KCNH2, KDR, MET, MMP12, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
10.6658 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.5649 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GSK3B, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP2, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
10.5649 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA2, CA9, CBR1, CDC25B, CDK6, CES1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, GSK3B, HSD11B1, HSD17B2, HTR2A, HTR2B, HTR5A, INSR, KDR, MET, MMP2, MMP9, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, RORC, SIGMAR1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
10.2756 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
10.0687 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ADRA2A, ALOX15, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, GPR35, GSK3B, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MET, MMP12, MMP9, PIK3CB, PPARA, PTGS2, PTPN1, SLC6A4, SMAD3, SRC, TEK, TERT |
10.0461 |
[BP] GO:0097746 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SLC6A4 |
9.86494 |
[BP] GO:0035296 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SLC6A4 |
9.86494 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
ADRA2A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, GSK3B, HSPA1A, HTR1B, IGF1R, INSR, KCNH2, KDR, MMP2, MMP9, NR3C1, PIK3CA, PTGS2, RORC, SLC6A4, SMAD3, SRC, TERT |
9.85466 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, ADRA2A, AURKB, BCL2, CA2, CA7, CDK6, CNR1, DRD1, DRD2, DRD3, EGFR, HTR2A, HTR2B, HTR2C, KDR, PIK3CB, PTGS2, SRC, TNKS, TNKS2 |
9.79829 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GSK3B, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IDO1, IGF1R, KCNH2, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
9.79829 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GSK3B, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
9.59653 |
[BP] GO:0050880 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SLC6A4 |
9.55973 |
[BP] GO:0035150 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SLC6A4 |
9.52369 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
ADRA2A, AKR1B1, AR, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, PIM1, PTGS2, TEK, TERT |
9.4992 |
[BP] GO:0003013 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SLC6A4, SRC, TEK |
9.47601 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GPR35, GSK3B, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IDO1, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
9.47259 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CES1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, ESR1, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
9.45032 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GSK3B, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
9.41266 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, BCHE, CNR1, CNR2, DHFR, DRD1, DRD2, DRD3, EGFR, FABP3, FLT3, GSK3B, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PTGS2, SLC6A4, SRC, TEK, TYR |
9.33647 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, ADRA1A, APP, BCHE, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, HTR1B, HTR2A, PTGS2, SLC6A4 |
9.24718 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, ADRA1A, APP, BCHE, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, HTR1B, HTR2A, PTGS2, SLC6A4 |
9.24718 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GSK3B, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
9.06989 |
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, BCHE, CNR2, DRD1, DRD2, HTR1B, HTR2A, PTGS2, SLC6A4 |
9.00962 |
[BP] GO:0042310 |
None
|
ADRA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, SLC6A4 |
8.95952 |
[BP] GO:0042592 |
homeostatic process
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, HTR2A, HTR2B, HTR2C, INSR, KCNH2, MET, PIK3CA, PIK3CB, SMAD3, SRC, TERT |
8.84085 |
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, ADRA1A, ADRA2A, AR, BCHE, BCL2, CNR2, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, GPR35, GSK3B, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SLC6A4, SMAD3, SRC, TERT, XDH |
8.76777 |
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.75415 |
[BP] GO:0007188 |
None
|
ADORA1, ADRA1A, ADRA2A, CNR1, DRD1, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
8.74817 |
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, ADRA1A, ADRA2A, AR, BCHE, BCL2, CNR2, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, GPR35, GSK3B, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SLC6A4, SMAD3, SRC, TERT, XDH |
8.74817 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, HTR1D, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
8.72671 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, BCHE, CNR1, CNR2, DHFR, DRD1, DRD2, DRD3, EGFR, FABP3, FLT3, GSK3B, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PTGS2, SLC6A4, SRC, TEK, TYR |
8.69278 |
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.67793 |
[BP] GO:0071310 |
cellular response to organic substance
|
ADRA2A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, GSK3B, HTR1B, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PTGS2, RORC, SLC6A4, SMAD3, SRC |
8.64722 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, ADRA1A, CA2, CA7, CNR1, CNR2, DRD2, HTR1B |
8.63123 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, PTGS1, PTGS2 |
8.59716 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.57467 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.55025 |
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.52493 |
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, APP, AR, AXL, BCL2, CA1, CA2, CDK6, CNR1, CNR2, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GSK3B, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2 |
8.45595 |
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CES1, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, HTR1B, HTR1D, KDR, SLC6A4, SRC |
8.35359 |
[BP] GO:0007193 |
None
|
ADORA1, ADRA2A, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
8.33135 |
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, PTGS1, PTGS2 |
8.2967 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, PTGS1, PTGS2 |
8.28081 |
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.24505 |
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.24505 |
[BP] GO:0048878 |
chemical homeostasis
|
ADRA1A, ADRA2A, AKR1B1, APP, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, ESR1, FABP3, FABP4, GPR35, HTR2A, HTR2B, HTR2C, INSR, KCNH2, MET, PIK3CA, PIK3CB, SMAD3 |
8.23849 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, GSK3B, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.23849 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, GSK3B, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.17424 |
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, ADRA2A, BCL2, CNR1, DRD2, DRD3, GPR35, HTR1B, HTR2A, KCNH2, MMP9, PTGS2 |
8.12508 |
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, CA2, CNR1, CNR2, DRD1, DRD2, DRD3, ESR1, GPR35, GSK3B, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, INSR, PIK3CA, PIK3CB, SIGMAR1, SRC |
8.10707 |
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.06293 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, NQO2, PTGS1, PTGS2, TYR, XDH |
7.97577 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
7.95511 |
[BP] GO:0006805 |
xenobiotic metabolic process
|
BCHE, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, NQO2, PTGS1, RORC |
7.90598 |
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
7.86799 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
7.71945 |
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, GSK3B, HTR7, PGR, PPARA, RORC, SLC6A4, SRC, TOP2A |
7.68216 |
[BP] GO:0050795 |
None
|
ADORA1, CNR1, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B |
7.64823 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, GSK3B, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
7.64648 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, DRD2, EGFR, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, PIK3CB, PTPN1, SRC, TEK, XDH |
7.63718 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, MMP9, PTGS2, SRC, TERT |
7.46104 |
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, ADRA2A, ALOX15, APP, AXL, BCL2, CA2, CA7, CNR1, CYP19A1, DRD1, DRD2, DRD3, EGFR, GPR35, GSK3B, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, KCNH2, MMP12, MMP9, PIK3CB, PPARA, PTGS2, PTPN1, SLC6A4, SMAD3, SRC, TERT |
7.43768 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DHFR, DRD1, DRD2, DUSP3, EGFR, FLT3, GSK3B, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
7.42963 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CES1, CES2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DRD2, EGFR, FABP3, FABP4, FUT7, GBA2, MET, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2 |
7.35302 |
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ADRA1A, ADRA2A, ALOX15, AR, BCL2, CDK6, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, GSK3B, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
7.34209 |
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
7.34209 |
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
7.342 |
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, BCHE, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, HTR1A, INSR, PTGS2, SLC6A2, SLC6A4, SMAD3 |
7.31203 |
[BP] GO:0051716 |
cellular response to stimulus
|
ADRA2A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, EGFR, ESR1, FABP4, FLT3, GSK3B, HSPA1A, HTR1B, IGF1R, INSR, KCNH2, KDR, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TERT, TOP2A |
7.30161 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
7.29542 |
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, F10, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
7.28378 |
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
7.15507 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TYR |
7.06056 |
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, HSD11B2, HSPA1A, HTR1B, HTR2A, HTR2B, MMP2, PPARA, PTGS2, SLC6A4, SMAD3, SRC, TEK, TERT, TYR |
7.03521 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DHFR, DRD1, DRD2, DUSP3, EGFR, FLT3, GSK3B, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
6.92465 |
[BP] GO:0030335 |
positive regulation of cell migration
|
ADRA2A, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.90621 |
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, ADRA2A, APP, CDK6, CNR1, CNR2, CYP19A1, DHFR, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, GSK3B, HSPA1A, IDO1, IGF1R, MET, MMP12, MMP2, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
6.89588 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, ADRA2A, AKR1B1, CNR1, CYP19A1, CYP1A1, CYP1B1, DRD2, EGFR, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR2A, HTR2C |
6.85499 |
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
6.83541 |
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, DRD2, DUSP3, EGFR, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, PIK3CB, PTPN1, SRC, TEK, XDH |
6.82222 |
[BP] GO:0007198 |
None
|
HTR1A, HTR1B, HTR5A, HTR7 |
6.789 |
[BP] GO:0003008 |
None
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, BCHE, BCL2, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, EGFR, HSD11B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, INSR, KCNH2, PIK3CA, PTGS2, SLC6A4, SRC, TEK, TYR |
6.789 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CBR1, CDC25B, CDK6, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
6.78146 |
[BP] GO:0008217 |
None
|
ADORA1, ADRA1A, AR, CNR1, DRD2, DRD3, HSD11B2, PPARA, PTGS1, PTGS2, SMAD3 |
6.77081 |
[BP] GO:2000147 |
positive regulation of cell motility
|
ADRA2A, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.70471 |
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SRC, TEK, XDH |
6.63195 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, BCHE, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, EGFR, HSPA1A, IDO1 |
6.62909 |
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, GSK3B, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
6.62178 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, PTGS1, PTGS2 |
6.60252 |
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, DRD1, DRD2, EGFR, HTR1B, HTR2A, PTGS2 |
6.59153 |
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, FABP3, PPARA, PTGS1, PTGS2 |
6.5507 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FLT3, NR3C1, PTGS2, RORC, SLC6A4, SRC |
6.54394 |
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ADRA2A, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.54367 |
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CNR1, CNR2, CSNK2A1, CYP2D6, DHFR, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GSK3B, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
6.5149 |
[BP] GO:0007610 |
None
|
APP, BCHE, BCL2, CNR1, DRD1, DRD2, DRD3, EGFR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IDO1, INSR, PPARA, PTGS2, SLC6A4 |
6.49735 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CDK6, CYP1B1, DRD1, EGFR, ESR1, GSK3B, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PTGS2, RORC, SLC6A4, SRC |
6.48867 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, APP, BCL2, CES1, CYP19A1, CYP1A1, CYP1B1, DHFR, DRD1, DRD2, DRD3, GBA2, HTR1A, TYR |
6.48423 |
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES1, CES2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GSK3B, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
6.46899 |
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, FABP3, GBA2, GLO1, IDO1, PPARA, PTGS1, PTGS2 |
6.44977 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, ADRA2A, CNR1, CYP1A1, DRD3, FABP3, FLT3, HTR2A, HTR2B, HTR2C, PPARA, PTGS2, RORC, SRC, TEK |
6.36955 |
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, DRD3, HTR2A, HTR2B, HTR2C, KDR, SRC |
6.36205 |
[BP] GO:0040017 |
positive regulation of locomotion
|
ADRA2A, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.33904 |
[BP] GO:0023052 |
None
|
ADORA1, ADRA1A, AR, CNR1, DRD1, DRD2, DRD3, ESR2, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, KCNH2, PGR, SLC6A2, TEK |
6.31391 |
[BP] GO:0007267 |
None
|
ADORA1, ADRA1A, AR, CNR1, DRD1, DRD2, DRD3, ESR2, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, SLC6A2, TEK |
6.30915 |
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SLC6A4, SMAD3, SRC, TEK, TERT |
6.30763 |
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
6.30748 |
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, IDO1, INSR, KCNH2, KDR, MET, MMP12, MMP9, PIK3CA, PIM1, PTGS2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS2, XDH |
6.30278 |
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, GSK3B, HTR2B, IGF1R, INSR, KCNH2, KDR, MET, NUAK1, PIK3CA, PIM1, SRC, TEK, TNKS |
6.27953 |
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
6.25876 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, GSK3B, HSD11B1, HSD17B2, HTR5A, INSR, KDR, MMP9, PGR, PIK3CA, PIM1, PPARA, PTGS2, RORC, SIGMAR1, SMAD3, SRC, TEK, TYR |
6.2345 |
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, SRC, TEK |
6.19607 |
[BP] GO:0007154 |
None
|
ADORA1, ADRA1A, AR, AXL, BCL2, CNR1, DRD1, DRD2, DRD3, ESR2, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, PTGS2, SLC6A2, TEK |
6.17309 |
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SLC6A4, SMAD3, SRC, TEK, TERT |
6.17309 |
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, AR, BCHE, BCL2, CA2, EGFR, FLT3, HSD11B2, HTR1B, NR3C1, PTGS2, SRC |
6.14879 |
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
6.12299 |
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GSK3B, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
6.09703 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, PTGS1, PTGS2 |
6.08567 |
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ADRA1A, ALOX15, APP, DRD2, DUSP3, EGFR, HTR2A, HTR2B, HTR2C, KDR, PTPN1, SRC, TEK |
6.05238 |
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, PIK3CB, PTGS2, TNKS, TNKS2 |
6.00925 |
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.98775 |
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.92307 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, HTR1B, KCNH2, KDR, NR3C1, PTGS2, SRC |
5.91447 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CBR1, CDC25B, CDK6, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, HTR2C, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
5.91187 |
[BP] GO:0050801 |
ion homeostasis
|
ADRA1A, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, FABP3, GPR35, HTR2A, HTR2B, HTR2C, KCNH2, PIK3CB, SMAD3 |
5.89939 |
[BP] GO:0006939 |
None
|
ADRA1A, DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7 |
5.88684 |
[BP] GO:0032845 |
None
|
ADORA1, ADRA2A, BCL2, DRD2, HTR2A, HTR2B, HTR2C, SRC, TNKS, TNKS2 |
5.86208 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, ADRA2A, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DUSP3, ESR1, FABP4, GPR35, GSK3B, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TNKS |
5.86121 |
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, ADRA1A, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, DHFR, DRD2, EGFR, ESR1, ESR2, F3, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, INSR, MET, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.86121 |
[BP] GO:0051952 |
None
|
ADORA1, ADRA2A, CNR1, DRD1, DRD2, DRD3, HTR1B, HTR2A |
5.80497 |
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, ADRA2A, APP, BCL2, CA2, CA7, CNR1, DRD1, DRD2, DRD3, GPR35, HTR1A, HTR1B, HTR2A, KCNH2, MMP9, PTGS2, SLC6A4 |
5.78172 |
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SLC6A4, SMAD3, SRC, TEK, TERT |
5.77269 |
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
ADRA2A, AKR1B1, APEX1, APP, AR, DRD1, EGFR, ESR1, FLT3, GSK3B, HTR1B, IGF1R, INSR, MMP2, NR3C1, PTGS2, SLC6A4, SMAD3, SRC |
5.77269 |
[BP] GO:0048513 |
animal organ development
|
ACHE, ADRA1A, AR, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PIK3CA, PPARA, SMAD3, SRC, TEK, TYR |
5.72762 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, PIM1, SRC, TEK |
5.6581 |
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK |
5.6581 |
[BP] GO:0099536 |
None
|
CNR1, DRD1, DRD2, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC6A2 |
5.64807 |
[BP] GO:0099537 |
None
|
CNR1, DRD1, DRD2, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC6A2 |
5.64807 |
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ADRA1A, ALOX15, APP, DRD2, EGFR, HTR2A, HTR2B, HTR2C, KDR, SRC, TEK |
5.64473 |
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCHE, BCL2, EGFR, FLT3, HSD11B2, HTR1B, NR3C1, PTGS2, SRC |
5.58728 |
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, PTGS2, SLC6A4 |
5.5774 |
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
5.52882 |
[BP] GO:0090066 |
None
|
ADORA1, ADRA1A, ADRA2A, ALOX15, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SLC6A4 |
5.47239 |
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
5.46593 |
[BP] GO:0098771 |
inorganic ion homeostasis
|
ADRA1A, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, KCNH2, PIK3CB, SMAD3 |
5.45672 |
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, ADRA2A, APP, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, DRD3, EGFR, GSK3B, HTR2B, INSR, KCNH2, MMP12, PTGS2, SLC6A4, SMAD3, SRC, TERT |
5.44913 |
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRA1A, ADRA2A, APP, AURKB, BCL2, CDC25B, DHFR, DRD2, EGFR, ESR1, F3, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, INSR, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.44624 |
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, ADRA1A, APP, CA2, CA7, DRD1, DRD2, EGFR, PTGS2 |
5.43043 |
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, DHFR, DRD1, DRD2, EGFR, GSK3B, HSD11B2, HSPA1A, HTR1A, HTR2C, IDO1, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, PTPN1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TOP2A |
5.38639 |
[BP] GO:0007200 |
None
|
ADRA1A, ADRA2A, DRD1, DRD2, ESR1, HTR2A, HTR2B, HTR2C |
5.38587 |
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, PPARA, PTGS2, SRC, TEK |
5.37417 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRA1A, ADRA2A, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, HSPA1A, HTR2A, HTR2B, IDO1, KDR, MET, MMP12, MMP9, PIM1, PTGS2, SMAD3, SRC, TEK, TERT |
5.36652 |
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, GSK3B, HTR2B, IGF1R, INSR, KCNH2, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TNKS |
5.36596 |
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GSK3B, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
5.33015 |
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, APP, AR, AURKB, AXL, BCHE, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, GSK3B, HSPA1A, HTR1A, HTR2B, HTR2C, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
5.28488 |
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
ADRA2A, APEX1, APP, AR, AURKB, BCL2, CNR1, CSNK2A1, CYP2D6, DHFR, DRD2, DRD3, DUSP3, ESR1, ESR2, ESRRA, FABP4, GSK3B, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, MET, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
5.2351 |
[BP] GO:0050890 |
None
|
ADORA1, APP, BCHE, CNR1, DRD1, DRD2, DRD3, EGFR, HTR2A, INSR, PTGS2, SLC6A4 |
5.20314 |
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.19822 |
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
5.15128 |
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRA1A, ADRA2A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GSK3B, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
5.11884 |
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DHFR, DRD2, EGFR, PPARA, SMAD3 |
5.04156 |
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.00176 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, FABP3, GBA2, GLO1, IDO1, PIM1, PPARA, PTGS1, PTGS2, TYR |
4.96235 |
[BP] GO:0007611 |
None
|
APP, BCHE, CNR1, DRD1, DRD2, DRD3, EGFR, HTR2A, INSR, PTGS2, SLC6A4 |
4.91963 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.91824 |
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.91444 |
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, ADRA1A, APP, AR, BCHE, BCL2, CDK6, CYP1B1, DRD2, FABP3, HSPA1A, IDO1, PTGS2, SLC6A4, SMAD3, TERT, XDH |
4.91444 |
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, IDO1, KDR, MET, MMP12, PPARA, PTGS2, SMAD3, TEK |
4.91204 |
[BP] GO:0007268 |
None
|
DRD1, DRD2, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC6A2 |
4.89715 |
[BP] GO:0098916 |
None
|
DRD1, DRD2, DRD3, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC6A2 |
4.89715 |
[BP] GO:0055080 |
cation homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, KCNH2, PIK3CB, SMAD3 |
4.89662 |
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
4.87144 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA |
4.87144 |
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, GSK3B, KDR, PIK3CB, SMAD3, SRC, TEK |
4.86095 |
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, ADRA2A, APP, BCL2, CNR1, DRD2, DRD3, GPR35, GSK3B, HSPA1A, HTR1B, HTR2A, KCNH2, MMP9, PTGS2 |
4.76313 |
[BP] GO:0050999 |
None
|
CNR1, CNR2, DHFR, EGFR, HTR2B, TERT |
4.75702 |
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, SRC, TEK |
4.75291 |
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRA1A, ADRA2A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GSK3B, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.72752 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2C19 |
4.72277 |
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.71437 |
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, DRD1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, IDO1, INSR, MMP2, MMP9, PGR, PTGS2, SLC6A4, SRC, TOP2A |
4.71437 |
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, DRD2, DRD3, ESR1, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.6736 |
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, INSR, SLC6A4, SRC, TERT |
4.66419 |
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TERT, TNKS, TOP2A |
4.63518 |
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HTR1B, MMP2, MMP9, PTGS2, TERT |
4.60955 |
[BP] GO:0050433 |
None
|
ADRA2A, CNR1, DRD2, DRD3, HTR1B, HTR2A |
4.60409 |
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, ADRA2A, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, GSK3B, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PTPN1, SMAD3 |
4.57921 |
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
4.55617 |
[BP] GO:0002031 |
None
|
DRD2, DRD3, HTR1B, HTR2B |
4.55271 |
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
4.54702 |
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, DRD3, HTR1A, TYR |
4.54573 |
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, MMP9, PTGS2, TERT |
4.53814 |
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, ADRA2A, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GSK3B, HTR2A, HTR2B, IGF1R, INSR, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
4.50786 |
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
4.42722 |
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GSK3B, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.42271 |
[BP] GO:0055074 |
calcium ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
4.40685 |
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DRD1, EGFR, GSK3B, HTR1B, IGF1R, INSR, MMP2, PTGS2, SLC6A4, SRC |
4.38349 |
[BP] GO:0014059 |
None
|
CNR1, DRD2, DRD3, HTR1B, HTR2A |
4.377 |
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, APP, AR, AXL, BCHE, BCL2, CBR1, CDC25B, CDK6, CES1, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, GSK3B, HTR2B, KDR, MET, MMP2, MMP9, PGR, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TOP2A |
4.35907 |
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, FABP3, GBA2, GLO1, IDO1, PIM1, PPARA, PTGS1, PTGS2, TYR |
4.35471 |
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
4.35247 |
[BP] GO:0055065 |
metal ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, KCNH2, PIK3CB, SMAD3 |
4.29957 |
[BP] GO:0033555 |
multicellular organismal response to stress
|
BCL2, DRD1, HTR1A, HTR2C, IDO1, SLC6A2 |
4.27125 |
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, DRD2, EGFR, ESR1, FABP4, HSPA1A, IDO1, MMP12, MMP2, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.26905 |
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, ADRA2A, DUSP3, EGFR, FLT3, HTR2A, HTR2B, IGF1R, INSR, PIK3CB, PTPN1, SRC |
4.26657 |
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX15, ALOX5, CBR1, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, FABP3, GBA2, GLO1, IDO1, PIM1, PPARA, PTGS1, PTGS2, TYR |
4.24482 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.24466 |
[BP] GO:0035265 |
organ growth
|
ADRA1A, AR, BCL2, CYP19A1, ESR1 |
4.23629 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PTGS1, PTGS2, SRC |
4.23629 |
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, CYP2D6, GSK3B, MET, MMP9, PPARA, SMAD3, SRC, TERT, TNKS |
4.23629 |
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CES1, CSNK2A1, CYP19A1, CYP1A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, PIK3CA, PIK3CB, PTGS1, PTGS2 |
4.23629 |
[BP] GO:0032768 |
None
|
CNR1, CNR2, DHFR, EGFR, HTR2B, TERT |
4.23629 |
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.23146 |
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DHFR, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.19881 |
[BP] GO:2001023 |
None
|
CNR1, DRD1, DRD2, DRD3, HTR1B, HTR2A, MET |
4.19247 |
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
4.17457 |
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GSK3B, HSD11B2, IGF1R, INSR, PPARA, PTGS2, SRC, TEK |
4.16594 |
[BP] GO:0051588 |
None
|
DRD1, DRD2, DRD3, HTR1A, HTR1B, HTR2C, SLC6A4 |
4.16458 |
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, PTGS2, SLC6A4, SMAD3, SRC, TERT, TNKS, TOP2A |
4.16458 |
[BP] GO:0050793 |
regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GSK3B, HTR2A, HTR2C, IDO1, INSR, KDR, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS2, XDH |
4.14723 |
[BP] GO:0051967 |
None
|
ADORA1, DRD2, HTR1B, HTR2A |
4.12993 |
[BP] GO:0030003 |
cellular cation homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
4.11775 |
[BP] GO:1900542 |
None
|
ADRA2A, DRD1, DRD2, DRD3, ESRRB, HTR1B, HTR1E, HTR2A, INSR, PPARA |
4.09259 |
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, BCHE, CSNK2A1, DRD1, DRD2, DRD3, HTR1A |
4.07255 |
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRA1A, ADRA2A, AR, BCL2, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, GSK3B, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
4.0668 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
4.05419 |
[BP] GO:0055082 |
cellular chemical homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, SMAD3 |
4.05419 |
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
4.05419 |
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DRD1, EGFR, GSK3B, HTR1B, IGF1R, INSR, MMP2, PTGS2, SLC6A4, SRC |
4.04622 |
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, EGFR, GSK3B, HTR7, PPARA, RORC, SLC6A4 |
4.04214 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.00489 |
[BP] GO:0006873 |
cellular ion homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
4.00394 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.00227 |
[BP] GO:0006140 |
None
|
ADRA2A, DRD1, DRD2, DRD3, ESRRB, HTR1B, HTR1E, HTR2A, INSR, PPARA |
3.99438 |
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCHE, BCL2, EGFR, FLT3, HSD11B2, NR3C1, PTGS2 |
3.9786 |
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, GSK3B, KDR, PIK3CB, SMAD3, SRC, TEK |
3.97299 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
3.95522 |
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR, HTR6 |
3.9368 |
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
3.90479 |
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
3.90216 |
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
ADRA1A, BCL2, DRD2, DRD3, DUSP3, ESR1, HSPA1A, IGF1R, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
3.89534 |
[BP] GO:1900274 |
regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
3.88036 |
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, TERT |
3.87576 |
[BP] GO:0035556 |
intracellular signal transduction
|
ADRA1A, ADRA2A, AKR1B1, AXL, BCL2, CYP1B1, DRD1, DRD2, DRD3, EGFR, GSK3B, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KCNH2, KDR, MET, NUAK1, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
3.87576 |
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, ADRA2A, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HTR2A, HTR2B, IGF1R, INSR, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
3.86516 |
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, ADRA2A, CNR1, CYP19A1, DRD2, DRD3, EGFR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MMP12, SLC6A4, SRC |
3.83683 |
[BP] GO:0009410 |
None
|
CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, HTR1B, NR3C1 |
3.83502 |
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, ADRA2A, AURKB, CDC25B, DRD2, EGFR, FLT3, HTR2A, HTR2B, INSR, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
3.81486 |
[BP] GO:0040014 |
regulation of multicellular organism growth
|
APP, BCL2, DRD2, DRD3, PIK3CA, TNKS2 |
3.78322 |
[BP] GO:0007613 |
None
|
CNR1, DRD1, DRD2, HTR2A, INSR, PTGS2, SLC6A4 |
3.76149 |
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, IDO1, PPARA, PTGS2, SMAD3, TEK |
3.7409 |
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, BCHE, DHFR, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SLC6A4, SRC |
3.72971 |
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DRD3, GSK3B, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.72151 |
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, EGFR |
3.71282 |
[BP] GO:0014821 |
None
|
DRD1, DRD2, HTR1D, HTR2B |
3.70611 |
[BP] GO:0019725 |
cellular homeostasis
|
ADRA1A, APEX1, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, SMAD3 |
3.69861 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, GSK3B, MET, MMP9, PPARA, SRC, TERT |
3.69376 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
3.69314 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
3.69314 |
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, ADRA2A, BCL2, CNR1, EGFR, HTR2B, MET, PIK3CA, PPARA, SMAD3 |
3.69242 |
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, ADRA2A, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HTR2A, HTR2B, IGF1R, INSR, PIK3CA, PIK3CB, PTPN1, SRC |
3.68385 |
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, ADRA2A, EGFR, FLT3, HTR2A, HTR2B, INSR, PIK3CB, PTPN1, SRC |
3.68137 |
[BP] GO:0003012 |
None
|
ADORA1, ADRA1A, DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, KCNH2, PIK3CA |
3.68137 |
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA |
3.66199 |
[BP] GO:1900543 |
None
|
ADRA2A, DRD2, DRD3, HTR1B, HTR1E, PPARA |
3.6566 |
[BP] GO:0050678 |
None
|
AR, CDK6, EGFR, F3, HTR2B, KDR, MMP12, PGR, SMAD3, TEK, XDH |
3.64701 |
[BP] GO:0032229 |
None
|
ADORA1, CNR2, HTR1B |
3.64132 |
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP2C19, CYP2D6 |
3.64132 |
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, ADRA2A, CDC25B, DRD2, EGFR, FLT3, HTR2A, HTR2B, INSR, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
3.64048 |
[BP] GO:0045980 |
None
|
ADRA2A, DRD2, DRD3, HTR1B, HTR1E, PPARA |
3.62679 |
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.61214 |
[BP] GO:0045776 |
None
|
ADORA1, CNR1, DRD2, DRD3, PPARA |
3.57952 |
[BP] GO:0006936 |
None
|
ADRA1A, DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, KCNH2, PIK3CA |
3.56181 |
[BP] GO:0050789 |
regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GSK3B, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
3.55563 |
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.55563 |
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3, HTR2A |
3.53833 |
[BP] GO:0090087 |
None
|
ACHE, ADORA1, ADRA2A, APP, CA2, CNR1, DRD2, DRD3, EGFR, GSK3B, HTR2B, HTR2C, MMP12, PTGS2, PTPN1, SMAD3, SRC |
3.53833 |
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
3.51956 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, FABP3, FABP4, FUT7, GBA2, GSK3B, HSPA1A, IDO1, MMP1, MMP12, MMP2, MMP9, PIK3CB, SRC, XDH |
3.50331 |
[BP] GO:0051046 |
None
|
ACHE, ADORA1, ADRA2A, CNR1, CYP19A1, DRD2, DRD3, EGFR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MMP12, SLC6A4, SRC |
3.47647 |
[BP] GO:0006811 |
None
|
ADRA1A, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, DRD3, FABP3, HTR2A, HTR2B, HTR2C, KCNH2, PPARA, SLC6A2, SLC6A4 |
3.47445 |
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, DRD1, DRD2, HTR2A, MET, PIK3CA |
3.4655 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2C19 |
3.45607 |
[BP] GO:0040008 |
regulation of growth
|
APP, AR, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR2, HSPA1A, INSR, PIK3CA, PIM1, SLC6A4, SMAD3, TNKS2 |
3.44843 |
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, GSK3B, KDR, SMAD3, TEK |
3.4467 |
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, ESR2, NR3C1, PGR, SRC |
3.44513 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, HTR1A, MET, PIK3CB, PIM1, SRC, TEK, TYR |
3.44513 |
[BP] GO:0009820 |
alkaloid metabolic process
|
BCHE, CYP1A2, CYP2D6 |
3.42876 |
[BP] GO:0014062 |
None
|
HTR1A, HTR1B, SLC6A4 |
3.42876 |
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.42876 |
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, DHFR, EGFR, INSR, PTGS2, SMAD3, XDH |
3.4224 |
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
3.39797 |
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, DRD2, MMP12, PPARA, SMAD3, TEK |
3.38706 |
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9, TERT |
3.38538 |
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ADRA1A, ADRA2A, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DHFR, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GSK3B, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.37342 |
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.36409 |
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, HTR5A, PTGS2, SLC6A4 |
3.34225 |
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, BCL2, CDK6, CYP1B1, DUSP3, GSK3B, IDO1, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, SMAD3, SRC, TEK |
3.33977 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
3.33821 |
[BP] GO:0033273 |
response to vitamin
|
ALPL, BCHE, CYP1A1, EGFR, PTGS2, TYR |
3.33411 |
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCHE, BCL2, CNR1, CYP1A1, EGFR, HSD11B2, PTGS2, SLC6A4, SRC, TYR |
3.33018 |
[BP] GO:0007568 |
aging
|
ADRA1A, APEX1, AURKB, BCL2, CNR1, CYP1A1, HTR2A, PTGS2, TERT |
3.32917 |
[BP] GO:0030815 |
None
|
ADRA2A, DRD2, DRD3, HTR1B, HTR1E |
3.32686 |
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, EGFR |
3.32686 |
[BP] GO:0051953 |
None
|
ADORA1, ADRA2A, CNR1, DRD2 |
3.31733 |
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
3.31314 |
[BP] GO:1904063 |
None
|
ADRA2A, DRD2, DRD3, GPR35, KCNH2, MMP9 |
3.31314 |
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK |
3.31314 |
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CES1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.31049 |
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
3.28968 |
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, ADRA2A, CDC25B, DRD2, EGFR, FLT3, HTR2A, HTR2B, INSR, PIK3CA, PIK3CB, PTPN1, SRC |
3.28847 |
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADRA1A, ADRA2A, DRD1, DRD2, DRD3, EGFR, HTR2B, HTR5A, KDR |
3.28098 |
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HTR1B, MMP2, MMP9, PTGS2, TERT |
3.2698 |
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.25542 |
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.25542 |
[BP] GO:0030800 |
None
|
ADRA2A, DRD2, DRD3, HTR1B, HTR1E |
3.25476 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.25476 |
[BP] GO:0007202 |
None
|
ADRA1A, EGFR, HTR2A, HTR2B |
3.25476 |
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, PGR, PTGS2, SRC |
3.25411 |
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRA1A, ADRA2A, DRD2, DRD3, EGFR, GPR35, HTR2A, HTR2C, KCNH2, PTGS2, SMAD3 |
3.25411 |
[BP] GO:0008150 |
biological_process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES1, CES2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.2448 |
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, ESRRB, F3, HTR2A, HTR2C, IDO1, INSR, KDR, PIM1, PTGS2, SMAD3, SRC, TEK, TERT |
3.19438 |
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
3.19242 |
[BP] GO:0042133 |
neurotransmitter metabolic process
|
ACHE, BCHE, CYP1B1, DHFR, HTR1A, SLC6A4 |
3.18602 |
[BP] GO:0051341 |
None
|
CNR1, CNR2, DHFR, EGFR, HTR2B, TERT |
3.18602 |
[BP] GO:0031329 |
regulation of cellular catabolic process
|
ADRA2A, APEX1, BCL2, CNR1, ESRRB, GSK3B, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PTPN1 |
3.17442 |
[BP] GO:0051172 |
None
|
ADRA2A, APEX1, APP, AR, AURKB, CSNK2A1, DHFR, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HSPA1A, HTR1B, HTR1E, IGF1R, MMP12, MMP9, NR3C1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
3.16992 |
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, EGFR, F10, FLT3, GSK3B, IGF1R, INSR, KDR, MET, SRC, TEK, TNKS, TOP2A |
3.15583 |
[BP] GO:0048638 |
regulation of developmental growth
|
APP, AR, BCL2, DRD2, DRD3, INSR, PIK3CA, PIM1, SLC6A4, TNKS2 |
3.13691 |
[BP] GO:0001975 |
None
|
CNR2, DRD1, DRD2, DRD3 |
3.12558 |
[BP] GO:0007612 |
None
|
APP, BCHE, DRD1, DRD2, DRD3, INSR, PTGS2 |
3.1202 |
[BP] GO:0019933 |
None
|
ADRA1A, ADRA2A, DRD1, DRD2, DRD3, HTR5A |
3.11129 |
[BP] GO:0010628 |
positive regulation of gene expression
|
APP, AR, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, GSK3B, HSPA1A, INSR, MET, MMP12, NR3C1, PGR, PIK3CB, PPARA, RORC, SLC6A4, SMAD3, SRC, TERT, TNKS, TOP2A |
3.08938 |
[BP] GO:0031623 |
None
|
ACHE, DRD2, DRD3, HTR1B, HTR2B |
3.07017 |
[BP] GO:0007584 |
response to nutrient
|
ALPL, BCHE, CNR1, CYP1A1, EGFR, PTGS2, SLC6A4, TYR |
3.05614 |
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ADRA1A, ALPL, AXL, BCHE, BCL2, CDK6, CNR1, CNR2, CYP1A1, CYP1A2, DRD3, EGFR, HSD11B2, HTR2A, IDO1, MMP12, PTGS2, SLC6A4, SMAD3, SRC, TYR |
3.04871 |
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
3.04189 |
[BP] GO:0034766 |
None
|
ADRA2A, DRD2, DRD3, GPR35, KCNH2, MMP9 |
3.03938 |
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, HSPA1A, INSR, TERT, TNKS |
3.02171 |
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
3.01519 |
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CNR1, CYP1A1, DRD1, EGFR, ESR1, PGR, PTGS2, SLC6A4, SRC |
3.01519 |
[BP] GO:0010906 |
None
|
ESRRB, GSK3B, INSR, PPARA, RORC, SRC |
2.99195 |
[BP] GO:0003014 |
None
|
ADORA1, ADRA1A, AKR1B1, BCL2, DRD2, HSD11B2 |
2.99195 |
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, HSPA1A, IDO1, MMP12, MMP2, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC |
2.96463 |
[BP] GO:0042391 |
None
|
ADORA1, ADRA1A, APP, BCL2, CNR1, CNR2, DRD1, GPR35, KCNH2, KDR, SRC |
2.95885 |
[BP] GO:0043266 |
None
|
ADORA1, ADRA2A, DRD1, DRD2, HTR2A, KCNH2 |
2.94566 |
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, RORC, TOP2A |
2.94566 |
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.93838 |
[BP] GO:0010517 |
regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.93838 |
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, ADRA2A, CNR1, CYP19A1, DRD2, EGFR, HTR1A, HTR2A, HTR2C |
2.93838 |
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.93686 |
[BP] GO:0045934 |
None
|
ADRA2A, APEX1, AR, AURKB, DRD2, DRD3, ESR1, ESR2, ESRRA, FABP4, HSPA1A, HTR1B, HTR1E, MMP12, NR3C1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2 |
2.92454 |
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCHE, BCL2, CNR1, CYP1A1, EGFR, HSD11B2, PTGS2, SLC6A4, SRC, TYR |
2.91877 |
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, IDO1, MMP12 |
2.9109 |
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.9109 |
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DHFR, DUSP3, EGFR, GSK3B, HSPA1A, IGF1R, MET, NUAK1, PTGS2, PTPN1, TERT, XDH |
2.9109 |
[BP] GO:0019229 |
None
|
ADRA1A, ADRA2A, EGFR, HTR2A, PTGS2 |
2.91013 |
[BP] GO:0019935 |
None
|
ADRA1A, ADRA2A, DRD1, DRD2, DRD3, HTR5A |
2.90791 |
[BP] GO:0034763 |
None
|
ADRA2A, DRD2, DRD3, GPR35, KCNH2, MMP9 |
2.90791 |
[BP] GO:0002209 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.9046 |
[BP] GO:0001662 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.9046 |
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MET, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.89331 |
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.88977 |
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.88977 |
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.88977 |
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.88977 |
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
2.88417 |
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, ADRA2A, APP, AR, BCL2, CNR1, CSNK2A1, DRD2, DRD3, EGFR, GSK3B, HTR2B, MMP12, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.87652 |
[BP] GO:0042220 |
None
|
CNR1, DRD2, DRD3, HTR1B |
2.85686 |
[BP] GO:0045777 |
None
|
ADORA1, ADRA1A, CNR1, HSD11B2 |
2.85686 |
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2, HTR2A |
2.85686 |
[BP] GO:0045744 |
None
|
ADRA2A, DRD2, DRD3, MET |
2.85686 |
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.85686 |
[BP] GO:0019371 |
None
|
CBR1, PTGS1, PTGS2 |
2.85686 |
[BP] GO:0060193 |
positive regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.85686 |
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, TERT |
2.82616 |
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.82616 |
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.82616 |
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC, TERT |
2.82568 |
[BP] GO:0022029 |
None
|
DRD1, DRD2, EGFR, HTR6 |
2.8129 |
[BP] GO:0042596 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.8129 |
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, HTR2C, PTGS2 |
2.80197 |
[BP] GO:0060402 |
None
|
ADRA1A, DRD2, HTR2A, HTR2B, HTR2C |
2.80197 |
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
2.80197 |
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, PTGS2, SRC |
2.79908 |
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, CDK6, GSK3B, KDR, SMAD3, TEK |
2.79313 |
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CNR2, CYP19A1, DRD1, DRD2, DRD3, PPARA, SMAD3, TEK |
2.77734 |
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F3, FABP4, IDO1, KDR, MET, PTGS2, SMAD3 |
2.77734 |
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, ADRA2A, DUSP3, EGFR, FLT3, HTR2A, HTR2B, IGF1R, INSR, PIK3CB, PTPN1, SRC |
2.7767 |
[BP] GO:2000026 |
regulation of multicellular organismal development
|
APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, GSK3B, IDO1, INSR, KDR, PIM1, PTGS2, SLC6A4, SMAD3, SRC, TEK, TERT, XDH |
2.77638 |
[BP] GO:0051926 |
negative regulation of calcium ion transport
|
ADRA2A, BCL2, DRD2, GPR35, PTGS2 |
2.7761 |
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.76993 |
[BP] GO:0045907 |
None
|
ADRA1A, EGFR, HTR2A, PTGS2 |
2.76993 |
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, ADRA2A, EGFR, FLT3, HTR2A, HTR2B, INSR, PIK3CB, PTPN1, SRC |
2.75993 |
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.75844 |
[BP] GO:0015872 |
None
|
DRD1, SLC6A2, SLC6A4 |
2.75844 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
2.75844 |
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.75145 |
[BP] GO:0051254 |
None
|
APP, AR, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.73743 |
[BP] GO:0010959 |
None
|
ADORA1, ADRA2A, BCL2, DRD1, DRD2, DRD3, GPR35, HTR2A, KCNH2, PTGS2 |
2.72511 |
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
ADRA1A, DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3 |
2.72082 |
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, PTGS2, TYR |
2.72082 |
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, ADRA1A, ADRA2A, DRD2, EGFR, HTR2A, KCNH2, PTGS2 |
2.72082 |
[BP] GO:0071396 |
cellular response to lipid
|
AR, AXL, CDK6, EGFR, ESR1, FLT3, NR3C1, RORC, SLC6A4, SRC |
2.71832 |
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
2.71005 |
[BP] GO:0045913 |
None
|
ESRRB, HTR2A, INSR, PPARA, SRC |
2.69536 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, IDO1 |
2.66553 |
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.66022 |
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.66022 |
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
ADRA1A, CA2, CA7 |
2.66022 |
[BP] GO:0033604 |
None
|
ADRA2A, CNR1, DRD2 |
2.66022 |
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CNR1, CYP1B1, F3, GSK3B, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
2.63926 |
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, PPARA, SMAD3, TEK |
2.62108 |
[BP] GO:0009896 |
positive regulation of catabolic process
|
ADRA2A, CSNK2A1, ESRRB, GSK3B, HSPA1A, HTR2A, INSR, KDR, PIK3CB, PPARA, PTPN1 |
2.61055 |
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, PTGS2, SRC |
2.60696 |
[BP] GO:0030814 |
None
|
ADRA2A, DRD1, DRD2, DRD3, HTR1B, HTR1E |
2.60411 |
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, DRD2, DRD3, EGFR, ESR1, ESR2, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PIK3CB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.60356 |
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CNR1, CYP1B1, F3, GSK3B, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
2.60242 |
[BP] GO:0007212 |
None
|
DRD1, DRD2, DRD3, GSK3B |
2.59783 |
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3 |
2.59783 |
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, PTGS1, PTGS2 |
2.59783 |
[BP] GO:0007189 |
None
|
ADRA1A, ADRA2A, DRD1, DRD2, DRD3 |
2.5926 |
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.5926 |
[BP] GO:0050730 |
None
|
ADORA1, ADRA2A, APP, EGFR, FLT3, HTR2A, PTPN1, SRC |
2.59182 |
[BP] GO:0045893 |
None
|
APP, AR, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.59182 |
[BP] GO:1903508 |
None
|
APP, AR, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.59182 |
[BP] GO:1902680 |
None
|
APP, AR, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.5882 |
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.57416 |
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.57416 |
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.56873 |
[BP] GO:0002791 |
None
|
ACHE, ADORA1, ADRA2A, CNR1, DRD2, DRD3, EGFR, HTR2B, HTR2C, MMP12, SRC |
2.56427 |
[BP] GO:0014075 |
None
|
CNR2, DRD1, DRD2, DRD3 |
2.56015 |
[BP] GO:0051241 |
negative regulation of multicellular organismal process
|
ADORA1, ADRA1A, APP, AXL, BCL2, CDK6, DRD2, DRD3, EGFR, GPR35, GSK3B, IDO1, PTGS2, SLC6A4, SMAD3, TEK, TERT, XDH |
2.54523 |
[BP] GO:0071383 |
None
|
AR, EGFR, FLT3, NR3C1, SRC |
2.54408 |
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, GSK3B, HTR2A, INSR, PPARA, RORC, SRC |
2.54102 |
[BP] GO:0050679 |
None
|
AR, EGFR, F3, HTR2B, KDR, MMP12, TEK |
2.52615 |
[BP] GO:1904705 |
regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9, TERT |
2.52001 |
[BP] GO:0010675 |
None
|
ESRRB, GSK3B, INSR, PPARA, RORC, SRC |
2.52001 |
[BP] GO:0032413 |
None
|
ADRA2A, DRD2, DRD3, GPR35, MMP9 |
2.52001 |
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, GSK3B, HSPA1A, MMP9, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.50464 |
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GSK3B, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.50259 |
[BP] GO:0043467 |
regulation of generation of precursor metabolites and energy
|
ESRRB, GSK3B, HTR2A, INSR, PIK3CA, PPARA |
2.50259 |
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HTR2B, MMP12, SLC6A4, SRC |
2.49754 |
[BP] GO:0060401 |
None
|
ADRA1A, DRD2, HTR2A, HTR2B, HTR2C |
2.49631 |
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3 |
2.49301 |
[BP] GO:0051937 |
None
|
DRD1, SLC6A2, SLC6A4 |
2.49301 |
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.49301 |
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, NR3C1, SRC |
2.48901 |
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC, TEK |
2.44947 |
[BP] GO:0070201 |
None
|
ACHE, ADRA2A, APP, BCL2, CNR1, DRD2, DRD3, EGFR, GSK3B, HTR2B, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.44925 |
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.44403 |
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.44403 |
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, ADRA2A, DRD2, EGFR, INSR, PIK3CA, PIK3CB, PTPN1, SRC |
2.44061 |
[BP] GO:0060748 |
None
|
AR, PGR |
2.42548 |
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.42548 |
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.42548 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.42548 |
[BP] GO:0033602 |
None
|
CNR1, DRD2 |
2.42548 |
[BP] GO:0032227 |
negative regulation of synaptic transmission, dopaminergic
|
PTGS2, SLC6A4 |
2.42548 |
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.42111 |
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.42111 |
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.42111 |
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.42111 |
[BP] GO:0043268 |
None
|
ADORA1, ADRA2A, DRD1, KCNH2 |
2.41588 |
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
ADRA1A, DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C |
2.41207 |
[BP] GO:0001819 |
positive regulation of cytokine production
|
ADRA2A, CYP1B1, DRD2, HSPA1A, HTR2B, IDO1, MMP12, PTGS2, SMAD3, SRC |
2.40032 |
[BP] GO:0031331 |
positive regulation of cellular catabolic process
|
ADRA2A, ESRRB, GSK3B, HSPA1A, HTR2A, INSR, KDR, PIK3CB, PPARA, PTPN1 |
2.40032 |
[BP] GO:1901655 |
None
|
AKR1B1, AR, EGFR, NR3C1, SRC |
2.38743 |
[BP] GO:0006584 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.38052 |
[BP] GO:0009712 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.38052 |
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PTGS2, SMAD3, SRC, TERT |
2.37763 |
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTGS2, SLC6A4, TEK, TYR |
2.37763 |
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GSK3B, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.36088 |
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, GSK3B, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.35063 |
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.34877 |
[BP] GO:0030818 |
None
|
ADRA2A, DRD2, DRD3, HTR1B |
2.34683 |
[BP] GO:0032410 |
None
|
ADRA2A, DRD2, DRD3, GPR35, MMP9 |
2.34506 |
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, FABP3, FABP4, MET, PIK3CA, PIK3CB |
2.33043 |
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CNR1, CYP1B1, F3, GSK3B, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
2.32776 |
[BP] GO:0051781 |
None
|
AURKB, CDC25B, DRD2, DRD3, HTR2B |
2.32326 |
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.32326 |
[BP] GO:0051283 |
None
|
DRD2, HTR2A, HTR2B, HTR2C |
2.31402 |
[BP] GO:0051209 |
None
|
DRD2, HTR2A, HTR2B, HTR2C |
2.31402 |
[BP] GO:0097366 |
None
|
CNR2, DRD1, DRD2, DRD3 |
2.31402 |
[BP] GO:0060191 |
regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.30176 |
[BP] GO:0045595 |
regulation of cell differentiation
|
APP, AR, AXL, BCL2, CA2, CDK6, CNR1, DRD2, DRD3, EGFR, ESRRA, ESRRB, GSK3B, HTR2A, HTR2C, KDR, PPARA, PTGS2, RORC, SLC6A4, SMAD3, TERT, XDH |
2.28842 |
[BP] GO:0006928 |
movement of cell or subcellular component
|
ADRA2A, APP, AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, SRC, TEK |
2.28838 |
[BP] GO:0031099 |
regeneration
|
AXL, BCL2, CSNK2A1, DHFR, EGFR, FLT3 |
2.28414 |
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.28414 |
[BP] GO:0051000 |
None
|
DHFR, HTR2B, TERT |
2.28414 |
[BP] GO:0045821 |
None
|
ESRRB, HTR2A, INSR |
2.28414 |
[BP] GO:0042058 |
None
|
ADORA1, ADRA2A, APP, EGFR, MMP9 |
2.28414 |
[BP] GO:0042136 |
neurotransmitter biosynthetic process
|
ACHE, CYP1B1, DHFR, SLC6A4 |
2.28414 |
[BP] GO:0030803 |
None
|
ADRA2A, DRD2, DRD3, HTR1B |
2.28414 |
[BP] GO:0040007 |
None
|
ADRA1A, APP, AR, BCL2, CYP19A1, ESR1, SMAD3, SRC, TNKS2 |
2.24671 |
[BP] GO:0060359 |
None
|
CNR1, DRD1, DRD2, DRD3, HTR1B |
2.23903 |
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AR, AURKB, CSNK2A1, DHFR, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GSK3B, HSPA1A, IGF1R, KDR, MMP12, MMP9, NR3C1, PGR, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
2.23651 |
[BP] GO:0030534 |
None
|
APP, DRD1, DRD2, DRD3, HTR2A, PPARA |
2.22175 |
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.21893 |
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.21893 |
[BP] GO:0051197 |
None
|
ESRRB, HTR2A, INSR |
2.21893 |
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ACHE, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FLT3, FUT7, GBA2, GLO1, GSK3B, HSPA1A, HTR1A, HTR2B, HTR2C, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.21849 |
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, DRD3 |
2.21849 |
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PTGS2, SMAD3, XDH |
2.19996 |
[BP] GO:0032870 |
cellular response to hormone stimulus
|
ADRA2A, APEX1, AR, EGFR, ESR1, FLT3, INSR, NR3C1, SRC |
2.19807 |
[BP] GO:0051336 |
regulation of hydrolase activity
|
ADRA1A, APP, CSNK2A1, DRD2, EGFR, ESR1, F3, GSK3B, HSPA1A, HTR2A, HTR2B, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, XDH |
2.19807 |
[BP] GO:0030799 |
None
|
ADRA2A, DRD1, DRD2, DRD3, HTR1B, HTR1E |
2.19639 |
[BP] GO:0048608 |
reproductive structure development
|
AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, INSR, SRC |
2.19445 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, GBA2 |
2.19445 |
[BP] GO:1900372 |
None
|
ADRA2A, DRD2, DRD3, HTR1B |
2.19021 |
[BP] GO:0030809 |
None
|
ADRA2A, DRD2, DRD3, HTR1B |
2.19021 |
[BP] GO:0051223 |
None
|
ACHE, ADRA2A, APP, CNR1, DRD2, DRD3, EGFR, GSK3B, HTR2B, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.18617 |
[BP] GO:0043279 |
None
|
BCHE, CNR1, DRD2, DRD3, HTR1B |
2.18518 |
[BP] GO:0051302 |
None
|
AURKB, CDC25B, DRD2, DRD3, ESRRB, HTR2B |
2.18518 |
[BP] GO:0060341 |
regulation of cellular localization
|
ADRA2A, APP, AR, BCL2, CSNK2A1, DRD1, DRD2, DRD3, EGFR, GSK3B, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.17694 |
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.17694 |
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.17694 |
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.17694 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.17694 |
[BP] GO:0014827 |
None
|
HTR1D, HTR2B |
2.17694 |
[BP] GO:0043086 |
negative regulation of catalytic activity
|
ADRA2A, APP, CNR1, CNR2, CSNK2A1, DRD2, DRD3, DUSP3, FABP4, GSK3B, IGF1R, MMP9, PTGS2, PTPN1, SRC |
2.17219 |
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.17022 |
[BP] GO:0071880 |
None
|
ADRA1A, ADRA2A, DRD2 |
2.17022 |
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.16328 |
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, DRD2, EGFR, GSK3B, HTR2B, MMP12, PTGS2, SMAD3, SRC |
2.14872 |
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PTGS2, SLC6A4, TEK, TYR |
2.14812 |
[BP] GO:0045944 |
None
|
APP, AR, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, MET, MMP12, NR3C1, PGR, PPARA, SMAD3, TERT, TNKS, TOP2A |
2.14812 |
[BP] GO:0098657 |
import into cell
|
ACHE, ADORA1, ALOX15, APP, AXL, DRD2, DRD3, HTR1B, HTR2B, SLC6A2, SLC6A4 |
2.14342 |
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GSK3B, IGF1R, INSR, SRC |
2.14086 |
[BP] GO:0050877 |
None
|
ADORA1, APP, BCHE, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, EGFR, HTR2A, INSR, PTGS2, SLC6A4, TYR |
2.13796 |
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, ADRA2A, APEX1, APP, AR, AURKB, CA9, CSNK2A1, CYP1B1, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, HSPA1A, HTR1B, HTR1E, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, NR3C2, PGR, PIK3CA, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.13385 |
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, PTGS2, SRC, TEK |
2.12813 |
[BP] GO:0007631 |
None
|
APP, DRD1, DRD2, HTR1B, HTR2C |
2.11543 |
[BP] GO:0043112 |
None
|
ACHE, DRD2, DRD3, HTR1B, HTR2B |
2.11543 |
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.11543 |
[BP] GO:0015844 |
None
|
DRD1, SLC6A2, SLC6A4 |
2.11543 |
[BP] GO:0051968 |
None
|
DRD1, EGFR, PTGS2 |
2.11543 |
[BP] GO:0042749 |
None
|
ADORA1, DRD2, DRD3 |
2.11543 |
[BP] GO:0048729 |
tissue morphogenesis
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.11456 |
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.11437 |
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, SRC |
2.11437 |
[BP] GO:0050994 |
None
|
ADORA1, ADRA2A, CNR1, PPARA |
2.11437 |
[BP] GO:0009266 |
None
|
ADORA1, HSPA1A, HTR1B, HTR2A, HTR2B, PTGS2 |
2.09553 |
[BP] GO:0044283 |
None
|
AKR1B1, ALOX15, ALOX5, CES1, CYP19A1, CYP1A1, DHFR, IDO1, PTGS1, PTGS2 |
2.09172 |
[BP] GO:0034762 |
None
|
ADRA2A, APP, BCL2, CA2, DRD1, DRD2, DRD3, GPR35, KCNH2, MMP9 |
2.09172 |
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.0888 |
[BP] GO:0098900 |
None
|
ADRA1A, CNR1, CNR2, GPR35 |
2.08665 |
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, DRD3 |
2.08665 |
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.08665 |
[BP] GO:0030817 |
None
|
ADRA2A, DRD1, DRD2, DRD3, HTR1B |
2.06306 |
[BP] GO:0051194 |
None
|
ESRRB, HTR2A, INSR |
2.06306 |
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.06306 |
[BP] GO:0050995 |
None
|
ADORA1, ADRA2A, CNR1 |
2.06306 |
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.05892 |
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.05892 |
[BP] GO:1901360 |
None
|
ACHE, AKR1B1, AKR1B10, AOX1, APEX1, APP, AR, BCHE, BCL2, CES1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, ESR1, ESR2, ESRRA, ESRRB, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2B, HTR2C, IDO1, NR3C1, NR3C2, PGR, PPARA, PTGS2, RORC, SMAD3, TERT, TOP2A, TYR, XDH |
2.05063 |
[BP] GO:1904062 |
None
|
ADRA2A, APP, DRD1, DRD2, DRD3, GPR35, KCNH2, MMP9 |
2.05063 |
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, PIK3CA, PTGS2 |
2.04734 |
[BP] GO:1901184 |
None
|
ADORA1, ADRA2A, APP, EGFR, MMP9 |
2.04734 |
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CYP1B1, F3, KDR, PTGS2, TEK, TERT |
2.04461 |
[BP] GO:0032922 |
None
|
DRD2, DRD3, PPARA, RORC |
2.03179 |
[BP] GO:0051100 |
negative regulation of binding
|
AURKB, CYP2D6, GSK3B, MET, PPARA, TNKS |
2.03136 |
[BP] GO:0000904 |
cell morphogenesis involved in differentiation
|
AR, AXL, MET, SRC, TEK |
2.03015 |
[BP] GO:0030100 |
regulation of endocytosis
|
ALOX15, APP, AXL, DRD2, PIK3CB, PTPN1, SRC |
2.02739 |
[BP] GO:2000209 |
regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.01346 |
[BP] GO:0044062 |
None
|
ADORA1, DRD2, DRD3 |
2.01346 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.01346 |
[BP] GO:0048589 |
None
|
ADRA1A, APP, AR, BCL2, CYP19A1, ESR1, SMAD3, TNKS2 |
2.00771 |
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, MMP9, TERT |
2.00717 |
[BP] GO:1900180 |
regulation of protein localization to nucleus
|
APP, EGFR, GSK3B, PTGS2, SMAD3, SRC, TERT |
2.00717 |
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AXL, CA4, CNR1, CNR2, DRD1, DRD2, DRD3, F10, F3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, SLC6A2, SLC6A4, TEK |
9.98638 |
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, SLC6A2, SLC6A4, TEK |
8.53215 |
[CC] GO:0044459 |
plasma membrane part
|
ADORA1, ADORA3, ADRA1A, ADRA2A, ALOX15, APP, AXL, CA2, CA4, CA9, CNR1, CNR2, DRD1, DRD2, DRD3, DUSP3, EGFR, F10, F3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, PTGS2, SIGMAR1, SLC6A2, SLC6A4, SRC, TEK |
7.64823 |
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, ALOX15, ALPL, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, GBA2, GLO1, GPR35, GSK3B, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PTPN1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT |
7.64735 |
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCHE, BCL2, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, GPR35, GSK3B, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, MMP2, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TYR |
6.89654 |
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, APP, AR, AURKB, BCHE, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA7, CBR1, CDC25B, CDK6, CES1, CES2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR4, HTR5A, IDO1, INSR, KCNH2, KDR, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC6A4, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
4.96235 |
[CC] GO:0045121 |
membrane raft
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SLC6A2, SLC6A4, SRC, TEK |
4.88459 |
[CC] GO:0098857 |
membrane microdomain
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SLC6A2, SLC6A4, SRC, TEK |
4.85957 |
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, ALOX15, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, NR3C2, PIK3CA, PIK3CB, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC6A2, SLC6A4, SRC, TEK, TYR |
4.699 |
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCHE, BCL2, CES1, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DRD1, EGFR, F10, FLT3, GBA2, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGS1, PTGS2, PTPN1, SIGMAR1 |
4.54573 |
[CC] GO:0098589 |
membrane region
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SLC6A2, SLC6A4, SRC, TEK |
4.11094 |
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CES1, CES2, CYP19A1, CYP2D6, FLT3, GBA2, HSPA1A, HTR5A, KDR, PTGS2, PTPN1, SIGMAR1, XDH |
3.31778 |
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, BCHE |
3.25542 |
[CC] GO:0044464 |
cell part
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA7, CA9, CBR1, CDC25B, CDK6, CES1, CES2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.13691 |
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DRD1, EGFR, GBA2, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGS1, PTGS2, SIGMAR1 |
2.93181 |
[CC] GO:0098590 |
plasma membrane region
|
ADORA1, ADRA1A, ADRA2A, CA2, CA4, CA9, CNR1, DRD1, DRD2, EGFR, HTR2A, INSR, MET, PTGS2, SIGMAR1, SRC, TEK |
2.64922 |
[CC] GO:0005901 |
caveola
|
ADRA1A, HTR2A, INSR, PTGS2, SRC |
2.61302 |
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, ADRA2A, CA2, CA4, CA9, EGFR, TEK |
2.38903 |
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, CA2, CDK6, CNR1, CNR2, DRD1, DRD2, DRD3, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PTGS2, SLC6A2, SLC6A4, SRC, TEK |
2.28487 |
[CC] GO:0044853 |
plasma membrane raft
|
ADRA1A, HTR2A, INSR, PTGS2, SRC |
2.18518 |
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.17022 |
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, CA2, CDK6, CNR1, CNR2, DRD1, DRD2, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PTGS2, SLC6A2, SLC6A4, SRC, TEK |
2.16819 |
[CC] GO:0043227 |
membrane-bounded organelle
|
ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CBR1, CDK6, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GSK3B, HSPA1A, HTR2A, HTR4, HTR5A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.03136 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GSK3B, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
19.9271 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, AOX1, APP, AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SMAD3, TNKS, TYR, XDH |
18.5979 |
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AR, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SIGMAR1, TEK |
15.8248 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
15.6035 |
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, BCHE, DRD1, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, SLC6A4 |
15.4878 |
[MF] GO:0008227 |
None
|
ADRA1A, ADRA2A, DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
15.4878 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, BCHE, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DRD1, DRD2, DRD3, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC6A2, SLC6A4, SMAD3, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
15.386 |
[MF] GO:0043176 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
15.3009 |
[MF] GO:0051378 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
15.3009 |
[MF] GO:0004993 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
15.3009 |
[MF] GO:0099589 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
15.3009 |
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AR, AXL, CDK6, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SIGMAR1, TEK |
14.7094 |
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AR, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SIGMAR1, TEK |
14.3916 |
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AR, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SIGMAR1, SMAD3, TEK |
13.6954 |
[MF] GO:0099528 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
12.9082 |
[MF] GO:0030594 |
None
|
DRD1, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
11.8338 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCHE, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DUSP3, EGFR, F10, F3, FLT3, FUT7, GBA2, GLO1, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
11.476 |
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, BCHE, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
11.3989 |
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PPARA, PTPN1, RORC, SMAD3, TNKS |
11.1181 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, EGFR, FLT3, GSK3B, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, SIGMAR1, SLC6A4, SRC, TEK, TOP2A |
10.7592 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.68459 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.60253 |
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
9.33647 |
[MF] GO:0005496 |
steroid binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, RORC |
9.09646 |
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, TEK |
9.02371 |
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, TEK |
9.02371 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, NQO2, PTGS1, PTGS2, TYR, XDH |
8.92652 |
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, IDO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC6A2, SLC6A4, SMAD3, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
7.57515 |
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, PGR, PPARA, RORC |
7.19984 |
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, PGR, PPARA, RORC |
7.19984 |
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1 |
6.89654 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.44145 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, IDO1, PTGS1, PTGS2, SRC |
6.30397 |
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, ADRA2A, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GSK3B, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
6.17309 |
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRA1A, ADRA2A, CNR1, CNR2, DRD1, DRD2, DRD3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, SIGMAR1 |
6.15873 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, IDO1, PTGS1, PTGS2, SRC |
6.0225 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
5.68094 |
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, HSD11B2, HSD17B1, IDO1, NQO2, PTGS1, PTGS2, SRC, XDH |
5.64807 |
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, XDH |
5.46593 |
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, HSD17B1, IGF1R, INSR, NQO2, NR3C1 |
5.4562 |
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, PPARA, RORC |
5.14981 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, CBR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.01864 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
4.78102 |
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GSK3B, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
4.7274 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6 |
4.70861 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KCNH2, KDR, MET, NUAK1, PIK3CA, PIM1, SRC, TEK |
4.68604 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, PTGS1, PTGS2, TYR |
4.5909 |
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB |
4.55271 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
4.53814 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KCNH2, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
4.28995 |
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, ADRA2A, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SLC6A4, SMAD3, SRC |
4.23478 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, ADRA2A, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SLC6A4, SMAD3, SRC |
4.11775 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.0911 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, TYR |
4.02602 |
[MF] GO:0042802 |
identical protein binding
|
ACHE, ADRA2A, AOX1, APP, BCHE, BCL2, CSNK2A1, DRD2, EGFR, ESR1, ESR2, FLT3, IGF1R, KCNH2, KDR, MET, MMP9, NQO2, PGR, PTGS2, SLC6A4, SMAD3, TERT, TOP2A, TYR, XDH |
3.90479 |
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KCNH2, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
3.81304 |
[MF] GO:0019899 |
enzyme binding
|
ADRA2A, APP, AR, AURKB, BCHE, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2C19, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, GSK3B, HSPA1A, KCNH2, MET, NR3C1, PGR, PPARA, PTGS2, PTPN1, SLC6A4, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.71282 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
3.69314 |
[MF] GO:1901338 |
None
|
ADRA2A, DRD1, DRD2, DRD3 |
3.53833 |
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KCNH2, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TERT |
3.44843 |
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.4467 |
[MF] GO:0003674 |
molecular_function
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCHE, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES1, CES2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, DHFR, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GSK3B, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNH2, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.24683 |
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX15, ALOX5, IDO1, PTGS2 |
3.12558 |
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.10243 |
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.0648 |
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX15, ALOX5, IDO1, PTGS2 |
3.0648 |
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.94889 |
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.82616 |
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.82616 |
[MF] GO:0003990 |
acetylcholinesterase activity
|
ACHE, BCHE |
2.82616 |
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.82616 |
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.82616 |
[MF] GO:0046983 |
protein dimerization activity
|
ACHE, ADORA1, ADRA1A, ADRA2A, AOX1, AR, AXL, BCL2, DRD2, EGFR, FLT3, KCNH2, NQO2, PTGS2, SLC6A4, SMAD3, TERT, TOP2A, TYR, XDH |
2.77638 |
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3 |
2.75844 |
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2C19, CYP2D6 |
2.72511 |
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3 |
2.66022 |
[MF] GO:0042803 |
protein homodimerization activity
|
ACHE, ADRA2A, AOX1, BCL2, DRD2, FLT3, KCNH2, NQO2, PTGS2, SLC6A4, SMAD3, TERT, TOP2A, TYR, XDH |
2.60699 |
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.42548 |
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.42548 |
[MF] GO:0005330 |
None
|
SLC6A2, SLC6A4 |
2.42548 |
[MF] GO:0004104 |
cholinesterase activity
|
ACHE, BCHE |
2.42548 |
[MF] GO:0047374 |
None
|
CES1, CES2 |
2.42548 |
[MF] GO:0004935 |
None
|
ADRA1A, ADRA2A, DRD2 |
2.42111 |
[MF] GO:0008013 |
beta-catenin binding
|
AR, CSNK2A1, ESR1, GSK3B, SMAD3 |
2.36573 |
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.34683 |
[MF] GO:0008134 |
transcription factor binding
|
APEX1, AR, BCL2, ESR1, ESRRB, FLT3, GSK3B, PIM1, PPARA, SMAD3, SRC, TERT |
2.21893 |
[MF] GO:0051213 |
dioxygenase activity
|
ALOX15, ALOX5, IDO1, PTGS1, PTGS2 |
2.19996 |
[MF] GO:0052689 |
carboxylic ester hydrolase activity
|
ACHE, BCHE, CA1, CA2, CES1, CES2 |
2.19639 |
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.17694 |
[MF] GO:0032795 |
None
|
ADORA1, ADRA2A |
2.17694 |
[MF] GO:0051425 |
None
|
APP, INSR |
2.17694 |
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.17022 |