Prescription Description
| Prescription ID | TCMF1373 |
| Pinyin Name | Mu Xiang Bing Lang Wang |
| Chinese Name | 木香槟榔丸 |
| English Name | Aucklandiae and Arecae Pills |
| Function Description | 诸虫 |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1533 | Saussurea lappa | 木香 | TCMH1533 | |
| TCMH182 | Areca catechu | 槟榔 | TCMH182 | ITSAA732-14 |
| TCMH363 | Rheum officinale | 大黄 | TCMH363 | ITSAJ4685-14 |
| TCMH972 | Coptis chinensis | 黄连 | TCMH972 | ITSAO4469-14 |
| TCMH949 | Phellodendron amurense | 黄柏 | TCMH949 | ITSAM1586-14 |
| TCMH2265 | Cyperus rotundus | 香附 | TCMH2265 | GENG1049-15 |
| TCMH1662 | Pharbitis nil | 牵牛子 | TCMH1662 | |
| TCMH1695 | Pericarpium citri reticulatae viride | 青皮 | TCMH1695 | |
| TCMH1184 | Citrus reticulata | 橘皮 | TCMH1184 | ITSAA1245-14 |
| TCMH544 | Curcuma aeruginosa | 莪术 | TCMH544 | ITSAN2146-14 |
| TCMH1903 | Zingiber officinale | 生姜 | TCMH1903 | ITSAO3969-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT114 | CNR2 | Cannabinoid CB2 receptor | GPCR | P34972 |
| TCMT115 | CNR1 | Cannabinoid CB1 receptor | GPCR | P21554 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
Showing 1 to 10 of 102 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1182 | Streptococcus sanguinis |
| TCMT1183 | Candida albicans SC5314 |
| TCMT1188 | Leishmania braziliensis |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
Showing 1 to 10 of 75 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AXL, BCL2, CYP1B1, MMP9, SRC | 2.40307 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, FABP3, HSD17B2, KDR, MMP2, PTGES, PTGS2, SRC | 2.58974 |
| [BP] GO:0001503 | ossification | ALOX15, ALPL, BCL2, MMP2, MMP9 | 2.29356 |
| [BP] GO:0001505 | regulation of neurotransmitter levels | ACHE, CYP1B1, DRD1, DRD2, HTR1A, MAOA, PTGS2, TRPV1 | 3.17745 |
| [BP] GO:0001516 | None | PTGES, PTGS1, PTGS2 | 2.87783 |
| [BP] GO:0001659 | None | DRD1, DRD2, HTR2A, TRPV1 | 3.19952 |
| [BP] GO:0001662 | None | BCL2, DRD1, HTR1A, HTR2C | 3.24778 |
| [BP] GO:0001666 | response to hypoxia | BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SRC | 3.13928 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | ALOX15, CYP1A1, CYP1A2, CYP1B1, PTGES, PTGS1, PTGS2, TBXAS1 | 5.92536 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ALOX15, BCL2, DRD1, DRD2, FABP4, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, SRC, XDH | 2.84494 |
Showing 1 to 10 of 422 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| Acute myeloid leukemia_Homo sapiens_hsa05221 | PIK3CA, FLT3, PIM1, PIK3CB | 3.5031 |
| Adherens junction_Homo sapiens_hsa04520 | SRC, MET, IGF1R | 2.1701 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.5772 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | PIK3CA, BCL2, PIK3CB | 1.4773 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | PIK3CA, MMP2, BCL2, PIM1, PIK3CB, F3 | 4.8041 |
| Alcoholism_Homo sapiens_hsa05034 | MAOA, DRD1, DRD2 | 1.3082 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2, PIK3CA, PIK3CB | 2.8383 |
| Amoebiasis_Homo sapiens_hsa05146 | PIK3CA, PIK3CB | 1.093 |
| Amphetamine addiction_Homo sapiens_hsa05031 | MAOA, DRD1 | 1.339 |
| AMPK signaling pathway_Homo sapiens_hsa04152 | PIK3CA, PIK3CB, IGF1R | 1.6202 |
Showing 1 to 10 of 152 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples