Prescription Description
| Prescription ID | TCMF1038 |
| Pinyin Name | Die Da Zhen Tong Gao |
| Chinese Name | 跌打镇痛膏 |
| English Name | Die Da Zhen Tong Ointment |
| Function Description | 风寒湿痹, 跌打损伤 |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | SkeletalMuscle |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH2129 | Eupolyphaga sinensis | 土鳖虫 | TCMH2129 | GBMIN33972-13 |
| TCMH222 | Aconitum carmichaelii | 草乌 | TCMH222 | ITSAH2410-14 |
| TCMH1405 | Strychnos nux-vomica | 马钱子 | TCMH1405 | PPBI045-16 |
| TCMH363 | Rheum officinale | 大黄 | TCMH363 | ITSAJ4685-14 |
| TCMH1068 | Dalbergia odorifera | 降香 | TCMH1068 | ITSAJ4189-14 |
| TCMH1278 | Radix zanthoxyli | 两面针 | TCMH1278 | |
| TCMH986 | Scutellaria baicalensis | 黄芩 | TCMH986 | ITSAP4211-14 |
| TCMH949 | Phellodendron amurense | 黄柏 | TCMH949 | ITSAM1586-14 |
| TCMH921 | Polygonum cuspidatum | 虎杖 | TCMH921 | ITSAI2369-14 |
| TCMH183 | Dryobalanops aromatica | 冰片 | TCMH183 | GBVK4926-11 |
| TCMH190 | NA | 薄荷素油 | TCMH190 | |
| TCMH2585 | Cinnamomum camphora | 樟脑 | TCMH2585 | SDH069-14 |
| TCMH2009 | Methyl salicylatum | 水杨酸甲酯 | TCMH2009 | |
| TCMH189 | Mentholum | 薄荷脑 | TCMH189 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT114 | CNR2 | Cannabinoid CB2 receptor | GPCR | P34972 |
| TCMT115 | CNR1 | Cannabinoid CB1 receptor | GPCR | P21554 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
Showing 1 to 10 of 102 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1182 | Streptococcus sanguinis |
| TCMT1183 | Candida albicans SC5314 |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1191 | Bacillus megaterium |
Showing 1 to 10 of 73 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AXL, BCL2, CYP1B1, MMP9, PRKCD, SRC | 3.2317 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, BCHE, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC | 2.53607 |
| [BP] GO:0001503 | ossification | ALOX15, ALPL, BCL2, MMP2, MMP9 | 2.26236 |
| [BP] GO:0001505 | regulation of neurotransmitter levels | ACHE, BCHE, CYP1B1, DRD1, DRD2, HTR1A, PTGS2 | 2.3569 |
| [BP] GO:0001516 | None | MIF, PTGS1, PTGS2 | 2.87596 |
| [BP] GO:0001662 | None | BCL2, DRD1, HTR1A, HTR2C | 3.23717 |
| [BP] GO:0001666 | response to hypoxia | BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SRC | 3.10463 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, PTGS1, PTGS2, TBXAS1 | 5.79666 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ALOX15, BCL2, DRD1, DRD2, FABP4, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, SRC, XDH | 3.76624 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ALOX15, BCL2, DRD2, FLT3, HTR2A, HTR2B, HTR2C, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCD, PTGS2, SRC, XDH | 3.98124 |
Showing 1 to 10 of 436 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCB1 | 0.7073 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | PIK3CA, FLT3, PIM1, PIK3CB | 3.3382 |
| Adherens junction_Homo sapiens_hsa04520 | CSNK2A1, SRC, MET, IGF1R | 3.0159 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.5669 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | PIK3CA, BCL2, PIK3CB | 1.4173 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | PIK3CA, MMP2, PRKCD, BCL2, PIM1, PIK3CB, F3 | 5.8041 |
| Alcoholism_Homo sapiens_hsa05034 | DRD1, DRD2 | 0.7147 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2, PIK3CA, PIK3CB | 2.7224 |
| Amoebiasis_Homo sapiens_hsa05146 | PIK3CA, PIK3CB | 1.0277 |
| Amphetamine addiction_Homo sapiens_hsa05031 | DRD1 | 0.5805 |
Showing 1 to 10 of 167 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples