NPASS Compound

Natural Product: NPC330590

Natural Product ID	NPC330590
Common Name ? The InCHIKey will be temporarily assigned as the "Common Name" if no IUPAC name or alternative short name is available.	Amikacin
IUPAC Name	(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
Synonyms	Amikacin; Amikin
Synthetic Gene Cluster	n.a.
ChEMBL Identifier	CHEMBL177
PubChem CID	37768
Chemical Classification	CHEMONTID:0000000 [Organic compounds] [CHEMONTID:0004603] Organic oxygen compounds [CHEMONTID:0000323] Organooxygen compounds [CHEMONTID:0000011] Carbohydrates and carbohydrate conjugates [CHEMONTID:0003305] Aminosaccharides [CHEMONTID:0000282] Aminoglycosides [CHEMONTID:0001675] Aminocyclitol glycosides [CHEMONTID:0003575] 2-deoxystreptamine aminoglycosides [CHEMONTID:0003574] 4,6-disubstituted 2-deoxystreptamines

The Chemical Classification was calculated by Classyfire, a software for chemical taxonomy calculation. Reference: DOI:10.1186/s13321-016-0174-y.

Chemical Representations

RDKit 3D 83 85 0 0 0 0 0 0 0 0999 V2000 -4.0970 5.0576 -3.0097 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.7971 3.7068 -2.5617 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.9813 3.0870 -1.8607 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6170 1.6906 -1.4170 C 0 0 1 0 0 0 0 0 0 0 0 0 -3.4512 1.7539 -0.4811 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3559 1.1886 -0.7607 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2258 1.2331 0.1155 C 0 0 2 0 0 0 0 0 0 0 0 0 -0.1722 2.1551 -0.4478 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9677 2.1871 0.5370 C 0 0 2 0 0 0 0 0 0 0 0 0 1.9549 3.1120 0.0373 N 0 0 0 0 0 0 0 0 0 0 0 0 1.5678 0.8027 0.5831 C 0 0 2 0 0 0 0 0 0 0 0 0 0.5736 -0.2204 1.0881 C 0 0 1 0 0 0 0 0 0 0 0 0 -0.7051 -0.1811 0.2900 C 0 0 1 0 0 0 0 0 0 0 0 0 -1.7207 -0.9015 0.7933 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.2168 -1.9424 0.0273 C 0 0 1 0 0 0 0 0 0 0 0 0 -1.8882 -3.0755 0.7665 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.4778 -4.2319 0.3421 C 0 0 2 0 0 0 0 0 0 0 0 0 -1.5103 -5.3477 0.0117 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1926 -6.4880 -0.4115 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.4098 -4.0362 -0.8318 C 0 0 2 0 0 0 0 0 0 0 0 0 -4.4292 -3.0126 -0.3925 C 0 0 1 0 0 0 0 0 0 0 0 0 -3.6761 -1.7302 -0.1438 C 0 0 1 0 0 0 0 0 0 0 0 0 -4.2559 -1.0932 0.9663 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.3817 -2.8936 -1.4830 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.1118 -5.2085 -1.1152 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1538 -1.4696 0.8719 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6951 0.8534 1.3597 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8720 0.5629 0.6759 C 0 0 1 0 0 0 0 0 0 0 0 0 4.7652 1.6007 0.6023 O 0 0 0 0 0 0 0 0 0 0 0 0 5.8724 1.5090 1.4058 C 0 0 2 0 0 0 0 0 0 0 0 0 6.7925 2.6772 1.0209 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9950 2.6995 1.7942 N 0 0 0 0 0 0 0 0 0 0 0 0 6.6869 0.2606 1.2328 C 0 0 2 0 0 0 0 0 0 0 0 0 5.8516 -0.8731 0.7170 C 0 0 1 0 0 0 0 0 0 0 0 0 4.4603 -0.6851 1.2871 C 0 0 1 0 0 0 0 0 0 0 0 0 4.5897 -0.5479 2.6568 O 0 0 0 0 0 0 0 0 0 0 0 0 5.8150 -0.9445 -0.6721 O 0 0 0 0 0 0 0 0 0 0 0 0 7.1576 -0.0961 2.5108 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.6189 2.4504 0.6921 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.6717 1.1155 -0.6851 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.3472 5.3595 -3.6816 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1452 5.7284 -2.2193 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.5530 3.0709 -3.4306 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9782 3.7823 -1.8154 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.7947 3.0296 -2.6168 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.3626 3.7073 -1.0408 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3466 1.0364 -2.2533 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4439 1.5948 1.1423 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1341 1.8368 -1.4581 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6295 3.1494 -0.5495 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5458 2.4985 1.5087 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3472 3.7414 0.7552 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7039 3.5709 -0.8579 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8662 0.5335 -0.4641 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4308 -0.0303 2.1672 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4466 -0.5651 -0.7201 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7343 -2.0649 -0.9439 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1094 -4.6025 1.1760 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8796 -4.9913 -0.8175 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9002 -5.5853 0.9128 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8658 -7.3061 0.0748 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8180 -3.7231 -1.7055 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9069 -3.3973 0.5318 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.8904 -1.0886 -1.0471 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.1764 -1.4267 1.0456 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5907 -3.7925 -1.9343 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.2410 -2.3771 -1.2435 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9971 -5.4553 -2.0591 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0010 -1.6931 -0.0908 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5704 0.3396 -0.3844 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5737 1.6786 2.4801 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1019 2.5116 -0.0540 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2936 3.6420 1.0737 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8851 3.0464 2.7627 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6309 1.9061 1.6711 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5594 0.3977 0.5410 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3001 -1.8215 1.1243 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8911 -1.5893 1.0587 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1395 -1.2987 3.1094 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6936 -1.9184 -0.8855 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6685 0.3841 3.2219 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8682 3.0195 1.0813 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.1187 0.4371 -1.2771 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 2 3 1 0 3 4 1 0 4 5 1 0 5 6 2 3 6 7 1 0 7 8 1 0 8 9 1 0 9 10 1 0 9 11 1 0 11 12 1 0 12 13 1 0 13 14 1 0 14 15 1 0 15 16 1 0 16 17 1 0 17 18 1 0 18 19 1 0 17 20 1 0 20 21 1 0 21 22 1 0 22 23 1 0 21 24 1 0 20 25 1 0 12 26 1 0 11 27 1 0 27 28 1 0 28 29 1 0 29 30 1 0 30 31 1 0 31 32 1 0 30 33 1 0 33 34 1 0 34 35 1 0 35 36 1 0 34 37 1 0 33 38 1 0 5 39 1 0 4 40 1 0 13 7 1 0 22 15 1 0 35 28 1 0 1 41 1 0 1 42 1 0 2 43 1 0 2 44 1 0 3 45 1 0 3 46 1 0 4 47 1 6 7 48 1 1 8 49 1 0 8 50 1 0 9 51 1 1 10 52 1 0 10 53 1 0 11 54 1 6 12 55 1 1 13 56 1 6 15 57 1 6 17 58 1 1 18 59 1 0 18 60 1 0 19 61 1 0 20 62 1 6 21 63 1 1 22 64 1 6 23 65 1 0 24 66 1 0 24 67 1 0 25 68 1 0 26 69 1 0 28 70 1 6 30 71 1 1 31 72 1 0 31 73 1 0 32 74 1 0 32 75 1 0 33 76 1 6 34 77 1 1 35 78 1 1 36 79 1 0 37 80 1 0 38 81 1 0 39 82 1 0 40 83 1 0 M END

Standard InCHIKey	LKCWBDHBTVXHDL-RMDFUYIESA-N
Standard InCHI	InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1
SMILES	NCC[C@@H](C(=N[C@@H]1C[C@H](N)[C@H]([C@@H]([C@H]1O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)N)O)O)O[C@H]1O[C@H](CN)[C@H]([C@@H]([C@H]1O)O)O)O)O

Calculated Properties

Physi-Chem Properties

Molecular Weight:	585.29	Volume:	530.019 ? Van der Waals volume.
Dense:	1.104	LogP:	-3.3 ? The logarithm of the n-octanol/water distribution coefficients.
logD7.4:	-2.116 ? The logarithm of the n-octanol/water distribution coefficient at pH=7.4.	LogS:	-0.162 ? The logarithm of aqueous solubility value.
Rotatable Bonds:	10.0	Rigid Bonds:	19.0
TPSA:	335.43 ? Topological Polar Surface Area.	H-Bond Acceptor:	18.0
H-Bond Donor:	17.0	Rings:	3.0
Heavy Atoms:	18.0

MedChem Properties

QED Drug-Likeness Score:	0.084	GASA:	1.0 ? GASA represents the probability of being difficult to synthesize, ranging from 0 to 1.
Synthetic Accessibility Score:	5.581	Fsp³:	0.955
MCE-18:	71.349 ? MCE-18 stands for medicinal chemistry evolution.MCE-18≥45 is considered a suitable value.	Lipinski Rule-of-5:	Accepted
Pfizer Rule:	Rejected	GSK Rule:	Accepted
Golden Triangle Rule:	Accepted	BMS Rule:	1
Chelating Alert:	0	PAINS Alert:	0
Colloidal aggregators:	0.74	Fluc inhibitor:	0.0 ? The fluc inhibitor value is the probability of being fLuc inhibitors, within the range of 0 to 1.
Blue fluorescence:	0.036 ? The blue fluorescence value is the probability of being blue fluorescence, within the range of 0 to 1	Green fluorescence:	0.011 ? The green fluorescence value is the probability of being green fluorescence, within the range of 0 to 1
Reactive compounds:	0.113	Promiscuous compounds:	0.039

ADMET Properties (ADMETlab3.0)

ADMET: Absorption

Caco-2 Permeability:	-6.418	MDCK Permeability:	-5.253
Pgp-inhibitor:	0.0	Pgp-substrate:	1.0
PAMPA:	1.0 ? The experimental data for Peff was logarithmically transformed (logPeff). Molecules with log Peff values below 2.0 were classified as low-permeability (Category 0), while those with log Peff values exceeding 2.5 were classified as high-permeability (Category 1).	Human Intestinal Absorption (HIA):	1.0
20% Bioavailability (F20%):	0.466	30% Bioavailability (F30%):	0.993
50% Bioavailability (F50%):	0.986

ADMET: Distribution

Blood-Brain-Barrier Penetration (BBB):	0.0	MRP1:	0.017
Plasma Protein Binding (PPB):	11.13%	Volume Distribution (VD):	-0.663
Fu:	85.702% ? The fraction unbound in plasms.	OATP1B1 inhibitor:	0.986
OATP1B3 inhibitor:	1.0	BCRP inhibitor:	0.0
BSEP inhibitor:	0.0

ADMET: Metabolism

CYP1A2-inhibitor:	0.0	CYP1A2-substrate:	0.0
CYP2C19-inhibitor:	0.002	CYP2C19-substrate:	0.0
CYP2C9-inhibitor:	0.0	CYP2C9-substrate:	0.0
CYP2D6-inhibitor:	0.0	CYP2D6-substrate:	0.0
CYP3A4-inhibitor:	0.073	CYP3A4-substrate:	0.0
CYP2B6-substrate:	0.0	CYP2C8-inhibitor:	0.0
HLM stability:	0.0 ? Human liver microsomal (HLM) stability. Category 0: stable+ (HLM > 30 min); Category 1: unstable- (HLM ≤ 30 min). The output value is the probability of human liver microsomal instability, where a value closer to 1 indicates a higher likelihood of instability.

ADMET: Excretion

Clearance (CL):

0.708

Half-life (T1/2):

2.874

ADMET: Toxicity

hERG Blockers:	0.002	hERG Blockers (10um):	0.018
Human Hepatotoxicity (H-HT):	0.999	Drug-induced Liver Injury (DILI):	0.496
AMES Toxicity:	0.76	Rat Oral Acute Toxicity:	0.001
Maximum Recommended Daily Dose:	0.002	Skin Sensitization:	1.0
Carcinogencity:	0.011	Eye Corrosion:	0.0
Eye Irritation:	0.0	Respiratory Toxicity:	0.002
Drug-induced Neurotoxicity:	0.025	Ototoxicity:	1.0
Hematotoxicity:	0.12	Drug-induced Nephrotoxicity:	0.989
Genotoxicity:	0.9	RPMI-8226 Immunitoxicity:	0.078
A549 Cytotoxicity:	0.033	Hek293 Cytotoxicity:	0.006
BCF:	0.034 ? Bioconcentration factors are used for considering secondary poisoning potential and assessing risks to human health via the food chain. The unit is -log10[(mg/L)/(1000*MW)].	IGC50:	1.985 ? 48 hour Tetrahymena pyriformis IGC50. The unit of IGC50 is -log10[(mg/L)/(1000*MW)].
LC50DM:	3.566 ? 48 hour Daphnia magna LC50. The unit of LC50DM is -log10[(mg/L)/(1000*MW)].	LC50FM:	2.418 ? 96 hour fathead minnow LC50. The unit of LC50FM is -log10[(mg/L)/(1000*MW)].

Species Source

Organism ID	Organism Name	Taxonomy Level	Family	SuperKingdom	Isolation Part	Collection Location	Collection Time	Reference
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[14563159]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[15844961]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16378365]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16453790]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16724461]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17632514]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19231864]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21486005]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21504214]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[24224794]
NPO2453	Stachybotrys chartarum	Species	Stachybotryaceae	Eukaryota	Niphates recondita	Weizhou Island, Beibuwan Bay, Guangxi,China	n.a.	PMID[24387683]
NPO2453	Stachybotrys chartarum	Species	Stachybotryaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[24387683]
NPO2453	Stachybotrys chartarum	Species	Stachybotryaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[28530828]
NPO40647	Aspergillus sp. TJ29	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[28901763]
NPO18077	Liquidambar formosana	Species	Altingiaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[29019685]
NPO2453	Stachybotrys chartarum	Species	Stachybotryaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31265296]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[3170341]
NPO12970	Aspergillus fischeri	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[31920082]
NPO2453	Stachybotrys chartarum	Species	Stachybotryaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[32966070]
NPO40638	Penicillium sp. RO-11	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[33296194]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[3819734]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[5549382]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[COCONUT]
NPO12970	Aspergillus fischeri	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO2453	Stachybotrys chartarum	Species	Stachybotryaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO18077	Liquidambar formosana	Species	Altingiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]
NPO18077	Liquidambar formosana	Species	Altingiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[HerDing]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[TCMID]
NPO18077	Liquidambar formosana	Species	Altingiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCMID]
NPO18077	Liquidambar formosana	Species	Altingiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TCM_Taiwan]
NPO18077	Liquidambar formosana	Species	Altingiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[TM-MC]
NPO18077	Liquidambar formosana	Species	Altingiaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	Database[UNPD]
NPO12970	Aspergillus fischeri	Species	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]
NPO2453	Stachybotrys chartarum	Species	Stachybotryaceae	Eukaryota	n.a.	n.a.	n.a.	Database[UNPD]

Note for Reference:
In addition to directly collecting NP source organism data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated them from below databases:
☉ UNPD: Universal Natural Products Database [PMID: 23638153].
☉ StreptomeDB: a database of streptomycetes natural products [PMID: 33051671].
☉ TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine [PMID: 26156871].
☉ TCM@Taiwan: a Traditional Chinese Medicine database [PMID: 21253603].
☉ TCMID: a Traditional Chinese Medicine database [PMID: 29106634].
☉ TCMSP: The traditional Chinese medicine systems pharmacology database and analysis platform [PMID: 24735618].
☉ HerDing: a herb recommendation system to treat diseases using genes and chemicals [PMID: 26980517].
☉ MetaboLights: a metabolomics database [PMID: 27010336].
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

NP Quantity Composition/Concentration

Organism ID	Organism Name	Organism Material Preparation	Organism Part	NP Quantity (Standard)	NP Quantity (Minimum)	NP Quantity (Maximum)	Quantity Unit	Reference

Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP quantitative records for specific NP domains (e.g., NPS from foods or herbs) from domain-specific databases. These databases include:
☉ DUKE: Dr. Duke's Phytochemical and Ethnobotanical Databases.
☉ PHENOL EXPLORER: is the first comprehensive database on polyphenol content in foods [PMID: 24103452], its homepage can be accessed at here.
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

Biological Activity

Activity Type	# Activity
Inhibition	13
Frel	1
Kcat/Km	1
Kd	3
Potency	6
Activity	194
IC50	17
MIC=<90	1
AC50	64
MIC	1379
MIC50	127
MIC90	131
Log10 cfu	1
IZ	49
MIC80	1
MBC	22
BBC	5
C50k	1
Ratio	12
FC	13
log10cfu	4
HepSE_bilirubinemia	1
HepSE_cholecystitis	1
HepSE_cholelithiasis	1
HepSE_cirrhosis	1
HepSE_hepatic failure	1
HepSE_hepatic necrosis	1
HepSE_hepatomegaly	1
HepSE_jaundice	2
HepSE_liver fatty	1
HepSE_liver function tests abnormal	1
HepSE_Combined Scores	1
EC90	3
EC50	4
MIC>90	1
IC90	7
Hepatotoxicity (acute)	1
log10CFU/g	1
MIC>99	27
MIC>95	15
MBC>99.9	15
MNCC	1
GI	4
HepSE_liver disease	1
Hepatotoxicity (moderate)	2
Hepatotoxicity (granulomatous hepatitis)	1
Hepatotoxicity (benign tumour)	1
CC50	1
HepSE_elevated liver function tests	1
HepSE_hepatitis	1
ALT	12
ALB	12
ALP	12
AST	12
BUN	12
CHLORIDE	12
CHOL	12
CK	12
CREAT	12
GLUC	12
LDH	12
LIPASE	12
PHOS	12
POTASSIUM	12
SODIUM	12
BILI	12
PROT	12
URATE	12
BASO	12
EOS	12
LYM	12
MONO	12
NEUTSG	12
BASOLE	12
EOSLE	12
RBC	12
HCT	12
HGB	12
WBC	12
LYMLE	12
MCH	12
MCHC	12
MCV	12
MONOLE	12
NEUTLE	12
PLAT	12
CO2	6
RBCNUC	6

Activity Type	# Activity
Individual protein	72
Cell line	6
Single protein	6
Organism	2410
Unchecked	1
Nucleic acid	4
Others	17
Non-molecular	57
Phenotype	15

Molecular-level activity

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT144	Individual protein	Telomerase reverse transcriptase	Homo sapiens	Inhibition	=	25.0	%	PubChem BioAssay data set
NPT1249	Individual protein	Canalicular multispecific organic anion transporter 2	Homo sapiens	IC50	>	133000.0	nM	PMID[23956101]
NPT1028	Individual protein	Multidrug resistance-associated protein 4	Homo sapiens	IC50	>	133000.0	nM	PMID[23956101]
NPT1788	Individual protein	Alpha-1a adrenergic receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT267	Individual protein	Neuropeptide Y receptor type 1	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT230	Individual protein	Bradykinin B2 receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT291	Individual protein	Serotonin 2b (5-HT2b) receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT2879	Individual protein	Equilibrative nucleoside transporter 1	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT272	Individual protein	Kappa opioid receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT218	Individual protein	Adenosine A3 receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT1163	Individual protein	Glutamate (NMDA) receptor subunit zeta 1	Rattus norvegicus	AC50	>	10000.0	nM	PMID[37468498]
NPT222	Individual protein	Alpha-2a adrenergic receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT303	Individual protein	Vasopressin V1a receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT290	Individual protein	Serotonin 2a (5-HT2a) receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT263	Individual protein	Muscarinic acetylcholine receptor M2	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT2769	Individual protein	Thromboxane A2 receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT295	Individual protein	Serotonin transporter	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT224	Individual protein	Alpha-2c adrenergic receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT1647	Individual protein	Vasopressin V2 receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT1410	Individual protein	GABA receptor alpha-1 subunit	Rattus norvegicus	AC50	>	10000.0	nM	PMID[37468498]
NPT232	Individual protein	Cannabinoid CB1 receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT145	Individual protein	Mu opioid receptor	Homo sapiens	AC50	>	30000.0	nM	PMID[37468498]
NPT259	Individual protein	Melanocortin receptor 4	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT252	Individual protein	Histamine H2 receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT217	Individual protein	Adenosine A2a receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT249	Individual protein	Glucocorticoid receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT242	Individual protein	Dopamine D1 receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT225	Individual protein	Beta-1 adrenergic receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT271	Individual protein	Delta opioid receptor	Homo sapiens	AC50	>	30000.0	nM	PMID[37468498]
NPT243	Individual protein	Dopamine D2 receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT251	Individual protein	Histamine H1 receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT31	Individual protein	Cyclooxygenase-2	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT292	Individual protein	Serotonin 2c (5-HT2c) receptor	Homo sapiens	AC50	>	30000.0	nM	PMID[37468498]
NPT108	Individual protein	Estrogen receptor alpha	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT239	Individual protein	Cholecystokinin A receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT264	Individual protein	Muscarinic acetylcholine receptor M3	Homo sapiens	AC50	>	30000.0	nM	PMID[37468498]
NPT244	Individual protein	Dopamine D3 receptor	Homo sapiens	AC50	>	30000.0	nM	PMID[37468498]
NPT1464	Individual protein	Phosphodiesterase 4D	Homo sapiens	AC50	>	30000.0	nM	PMID[37468498]
NPT228	Individual protein	Norepinephrine transporter	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT216	Individual protein	Adenosine A1 receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT261	Individual protein	Monoamine oxidase A	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT262	Individual protein	Muscarinic acetylcholine receptor M1	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT226	Individual protein	Beta-2 adrenergic receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT2719	Individual protein	Voltage-gated L-type calcium channel alpha-1C subunit	Rattus norvegicus	AC50	>	10000.0	nM	PMID[37468498]
NPT223	Individual protein	Alpha-2b adrenergic receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT246	Individual protein	Dopamine transporter	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT299	Individual protein	Androgen Receptor	Rattus norvegicus	AC50	>	10000.0	nM	PMID[37468498]
NPT483	Individual protein	Prelamin-A/C	Homo sapiens	Potency	=	158.5	nM	PMID[12141872]
NPT4381	Individual protein	Cell division protein ftsZ	Escherichia coli K-12	Activity	=	35.0	%	PMID[12828466]
NPT713	Individual protein	Bile salt export pump	Homo sapiens	IC50	>	135000.0	nM	PMID[20829430]
NPT713	Individual protein	Bile salt export pump	Homo sapiens	IC50	>	133000.0	nM	PMID[23956101]
NPT5301	Individual protein	Motilin receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Frel	=	0.29	n.a.	PMID[15808490]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	50.0	nM	DOI[10.6019/CHEMBL1201861]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	>	100000.0	nM	PMID[17958396]
NPT612	Individual protein	Canalicular multispecific organic anion transporter 1	Homo sapiens	IC50	>	133000.0	nM	PMID[23956101]
NPT21966	Single protein	Polyketide synthase Pks13	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	MIC=<90	=	1.0	ug ml-1	PMID[30875203]
NPT4383	Nucleic acid	Ribosomal RNA A-site	n.a.	IC50	=	70.0	nM	PMID[27509271]
NPT4358	Individual protein	Type-1 angiotensin II receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT29430	Single protein	Neuronal acetylcholine receptor protein alpha-4 subunit	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT542	Individual protein	Progesterone receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT98	Individual protein	HERG	Homo sapiens	AC50	>	30000.0	nM	PMID[37468498]
NPT26263	Single protein	Aminoglycoside 3'-phosphotransferase type IIb	Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)	Kcat/Km	=	400000.0	/M/s	PMID[17088479]
NPT445	Individual protein	Peripheral myelin protein 22	Rattus norvegicus	Potency	n.a.	9074.3	nM	DOI[10.6019/CHEMBL1201861]
NPT5104	Individual protein	Phosphodiesterase 3A	Homo sapiens	AC50	>	30000.0	nM	PMID[37468498]
NPT5975	Individual protein	Cyclooxygenase-1	Rattus norvegicus	AC50	>	10000.0	nM	PMID[37468498]
NPT28814	Single protein	Ghrelin receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT92	Individual protein	Serotonin 1a (5-HT1a) receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT29454	Single protein	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	Homo sapiens	Inhibition	=	14.31	%	PMID[38318365]
NPT443	Individual protein	Histone acetyltransferase GCN5	Homo sapiens	Potency	n.a.	31622.8	nM	PMID[8289059]
NPT62	Individual protein	6-phospho-1-fructokinase	Trypanosoma brucei	Potency	n.a.	39810.7	nM	PMID[22280816]
NPT543	Individual protein	Pregnane X receptor	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT30151	Single protein	Melanocortin receptor 3	Homo sapiens	AC50	>	10000.0	nM	PMID[37468498]
NPT425	Individual protein	Serotonin 3a (5-HT3a) receptor	Homo sapiens	AC50	>	30000.0	nM	PMID[37468498]

In vitro activity

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT189	Cell line	Vero	Chlorocebus aethiops	IC50	>	62.5	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT189	Cell line	Vero	Chlorocebus aethiops	IC50	>	6.25	ug.mL-1	PMID[28552337]
NPT1886	Cell line	J774	Mus musculus	Activity	=	81.2	%	PMID[30282323]
NPT1886	Cell line	J774	Mus musculus	Activity	=	92.0	%	PMID[30282323]
NPT189	Cell line	Vero	Chlorocebus aethiops	MNCC	>	6.25	ug ml-1	PMID[27687968]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	1.0	ug.mL-1	DOI[10.1007/s00044-011-9810-2]
NPT2895	Organism	Providencia stuartii	Providencia stuartii	MIC	=	16.0	ug.mL-1	PMID[7525959]
NPT2895	Organism	Providencia stuartii	Providencia stuartii	MIC	=	1.0	ug.mL-1	PMID[22264170]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	=	4.0	ug.mL-1	PMID[9461657]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	4.0	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	32.0	ug.mL-1	PMID[17253840]
NPT1264	Organism	Burkholderia cepacia	Burkholderia cepacia	Activity	=	4.0	%	PMID[22691179]
NPT6019	Organism	Nocardia nova	Nocardia nova	MIC	=	0.00012	ug.mL-1	PMID[19349520]
NPT5769	Organism	Nocardia brasiliensis	Nocardia brasiliensis	MIC	=	0.001	ug.mL-1	PMID[9134742]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	=	2.0	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	Activity	=	3.5	%	PMID[23145884]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC50	=	2.0	ug.mL-1	PMID[18440233]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC90	=	4.0	ug.mL-1	DOI[10.1021/np50070a027]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	Activity	=	100.0	%	PMID[16933872]
NPT729	Organism	Micrococcus luteus	Micrococcus luteus	IZ	=	31.0	mm	PMID[9461657]
NPT1245	Organism	Streptococcus pasteurianus	Streptococcus pasteurianus	MIC	=	64.0	ug.mL-1	PMID[17665951]
NPT1245	Organism	Streptococcus pasteurianus	Streptococcus pasteurianus	MIC	=	512.0	ug.mL-1	PMID[17665951]
NPT1245	Organism	Streptococcus pasteurianus	Streptococcus pasteurianus	MIC	=	128.0	ug.mL-1	PMID[17665951]
NPT1245	Organism	Streptococcus pasteurianus	Streptococcus pasteurianus	MIC	=	32.0	ug.mL-1	PMID[17665951]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	0.125	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	0.5	ug.mL-1	PMID[26034885]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	1.5	ug.mL-1	PMID[17287123]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	2.0	ug.mL-1	PMID[10869199]
NPT1207	Organism	Acinetobacter	Acinetobacter	MIC	=	8.0	ug.mL-1	PMID[2778449]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	8.0	ug.mL-1	DOI[10.1016/S0960-894X(01)80580-1]
NPT5738	Organism	Enterobacter sp.	Enterobacter sp.	MIC90	=	16.0	ug.mL-1	PMID[16499319]
NPT5738	Organism	Enterobacter sp.	Enterobacter sp.	MIC50	=	2.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT5738	Organism	Enterobacter sp.	Enterobacter sp.	Activity	=	4.8	%	PMID[16472241]
NPT5738	Organism	Enterobacter sp.	Enterobacter sp.	Activity	=	95.2	%	PMID[6688829]
NPT1118	Organism	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC	=	8.0	ug.mL-1	PMID[12662097]
NPT1118	Organism	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC	=	0.5	ug.mL-1	Open TG-GATES in vivo data: Biochemistry
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	>	256.0	ug.mL-1	PMID[8182704]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	=	1.0	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	>	256.0	ug.mL-1	PMID[12762801]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	=	8.0	ug.mL-1	PMID[17363259]
NPT1264	Organism	Burkholderia cepacia	Burkholderia cepacia	MIC50	=	128.0	ug.mL-1	PMID[20158243]
NPT1264	Organism	Burkholderia cepacia	Burkholderia cepacia	MIC90	>	128.0	ug.mL-1	PubChem BioAssay data set
NPT5768	Organism	Acinetobacter pittii	Acinetobacter pittii	MIC	>=	16.0	ug.mL-1	PMID[11473434]
NPT5768	Organism	Acinetobacter pittii	Acinetobacter pittii	MIC50	=	32.0	ug.mL-1	PMID[23586757]
NPT5768	Organism	Acinetobacter pittii	Acinetobacter pittii	MIC90	>=	64.0	ug.mL-1	PubChem BioAssay data set
NPT5768	Organism	Acinetobacter pittii	Acinetobacter pittii	Activity	=	52.6	%	PMID[7528786]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	16.0	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	64.0	ug.mL-1	PMID[20392109]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	24.0	ug.mL-1	PMID[20088608]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC50	=	2.0	ug.mL-1	PubChem BioAssay data set
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC50	=	4.0	ug.mL-1	PMID[18512987]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC50	=	16.0	ug.mL-1	PMID[22148475]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	>	0.5	ug.mL-1	PMID[23999046]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC	>	0.5	ug.mL-1	DrugMatrix in vivo data: Pathology
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	>	2.0	ug.mL-1	PMID[10869199]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC90	=	16.0	ug.mL-1	PMID[24974345]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC50	=	8.0	ug.mL-1	PMID[12502331]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC	=	4.0	ug.mL-1	PMID[18597527]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC90	=	4.0	ug.mL-1	PMID[17070063]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC90	=	4.0	ug.mL-1	PMID[20547814]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC50	=	2.0	ug.mL-1	PMID[22781704]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC	=	0.5	ug.mL-1	DrugMatrix in vivo data: Pathology
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	0.25	ug.mL-1	DOI[10.1007/s00044-011-9964-y]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	Activity	=	31.6	%	PMID[21625478]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	Activity	=	63.6	%	PMID[22694318]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	Activity	=	63.2	%	PMID[17958396]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	Activity	=	100.0	%	PMID[23398362]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	Activity	=	96.4	%	DrugMatrix in vivo data: Hematology
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC90	=	32.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC	=	0.125	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC90	>	128.0	ug.mL-1	PMID[25978960]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC90	=	32.0	ug.mL-1	PMID[16643028]
NPT5311	Organism	Mycobacterium mageritense	Mycobacterium mageritense	MIC	=	0.5	ug.mL-1	PMID[23062825]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC90	=	8.0	ug.mL-1	PubChem BioAssay data set
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC90	=	8.0	ug.mL-1	PubChem BioAssay data set
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC90	=	16.0	ug.mL-1	PMID[18672864]
NPT2895	Organism	Providencia stuartii	Providencia stuartii	MIC90	=	8.0	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	Activity	=	0.0	%	PMID[22037378]
NPT5768	Organism	Acinetobacter pittii	Acinetobacter pittii	MIC	=	0.5	ug.mL-1	PubChem BioAssay data set
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	<=	2.0	ug.mL-1	PMID[10869199]
NPT2895	Organism	Providencia stuartii	Providencia stuartii	MIC50	=	2.0	ug.mL-1	PMID[15921415]
NPT2895	Organism	Providencia stuartii	Providencia stuartii	MIC	=	0.5	ug.mL-1	PMID[20805391]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC	=	1.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	=	0.5	ug.mL-1	PMID[23999046]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	>	128.0	ug.mL-1	PMID[26331426]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	Activity	=	99.0	%	PMID[18942825]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC	=	8.0	ug.mL-1	PMID[24224794]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MBC	=	1.0	ug ml-1	DrugMatrix in vivo data: Pathology
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MBC	=	8.0	ug ml-1	PubChem BioAssay data set
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MBC	=	2.0	ug ml-1	PMID[19651905]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	Activity	=	84.0	%	PMID[23327759]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	Activity	=	92.0	%	PMID[20384296]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	Activity	=	92.0	%	PMID[21044847]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	Activity	=	78.0	%	PMID[19258280]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	Activity	=	0.0	%	PMID[17665951]
NPT2895	Organism	Providencia stuartii	Providencia stuartii	MIC	=	8.0	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT1207	Organism	Acinetobacter	Acinetobacter	MIC	>	64.0	ug.mL-1	PMID[23977995]
NPT5764	Organism	Citrobacter	Citrobacter	MIC50	=	32.0	ug.mL-1	PMID[17287127]
NPT5738	Organism	Enterobacter sp.	Enterobacter sp.	MIC50	=	8.0	ug.mL-1	PMID[20801553]
NPT5738	Organism	Enterobacter sp.	Enterobacter sp.	MIC90	=	64.0	ug.mL-1	PMID[23567957]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC50	=	8.0	ug.mL-1	PMID[23501116]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC90	=	64.0	ug.mL-1	PMID[23501116]
NPT5775	Organism	Serratia sp.	Serratia sp.	MIC50	=	8.0	ug.mL-1	PMID[19743809]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	=	30.0	ug.mL-1	PMID[17118653]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	30.0	ug.mL-1	PMID[17118653]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	IZ	=	19.0	mm	DrugMatrix in vivo data: Pathology
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC	=	12.0	ug.mL-1	PMID[12713408]
NPT729	Organism	Micrococcus luteus	Micrococcus luteus	MIC	=	13650.0	nM	PMID[12762801]
NPT1824	Organism	Clostridium sporogenes	Clostridium sporogenes	MIC	=	25610.0	nM	PMID[11374942]
NPT1190	Organism	Salmonella enterica	Salmonella enterica	MIC	=	13660.0	nM	PMID[21035332]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC	=	37.5	ug.mL-1	PMID[19581457]
NPT729	Organism	Micrococcus luteus	Micrococcus luteus	MIC	=	14000.0	nM	PMID[19884381]
NPT1824	Organism	Clostridium sporogenes	Clostridium sporogenes	MIC	=	26000.0	nM	PMID[26547057]
NPT729	Organism	Micrococcus luteus	Micrococcus luteus	MIC	=	0.39	ug.mL-1	PMID[28400238]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC>95	=	0.125	uM	PMID[30742437]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC>95	=	0.0625	uM	PMID[30742437]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MBC>99.9	=	0.125	uM	PMID[30742437]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC	=	32.0	ug.mL-1	PMID[27509271]
NPT1264	Organism	Burkholderia cepacia	Burkholderia cepacia	MIC	>	32.0	ug.mL-1	PMID[27509271]
NPT4085	Organism	Bacillus licheniformis	Bacillus licheniformis	MIC	=	0.3	ug.mL-1	PMID[33296194]
NPT729	Organism	Micrococcus luteus	Micrococcus luteus	MIC	=	1000.0	nM	PMID[33582576]
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC90	=	3660.0	nM	PMID[32950907]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	>	512.0	ug.mL-1	PMID[37122541]
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC90	=	1.7	ug.mL-1	PMID[35307568]
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC50	=	0.62	ug.mL-1	PMID[35307568]
NPT28438	Unchecked	Unchecked	n.a.	MIC50	n.a.	n.a.	n.a.	PMID[33071055]
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	<=	250.0	nM	PMID[36037791]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	2.0	ug.mL-1	PMID[18955520]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	32.0	ug.mL-1	PMID[24164206]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	Kd	=	760000.0	nM	DOI[10.1007/s00044-013-0844-5]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	1.0	ug.mL-1	PMID[24507923]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC50	=	16.0	ug.mL-1	PMID[17043112]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC90	>	64.0	ug.mL-1	PMID[17043112]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC50	=	8.0	ug.mL-1	PMID[17043112]
NPT2906	Organism	Mycobacterium ulcerans	Mycobacterium ulcerans	Log10 cfu	=	3.92	n.a.	PMID[17101676]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	256.0	ug.mL-1	PMID[22584254]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	<=	0.00006	ug.mL-1	PMID[17194827]
NPT2905	Organism	Nocardia farcinica	Nocardia farcinica	MIC	=	0.001	ug.mL-1	PMID[25856683]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	0.00025	ug.mL-1	PMID[17194827]
NPT6020	Organism	Nocardia transvalensis	Nocardia transvalensis	MIC	=	0.032	ug.mL-1	PMID[8411013]
NPT4584	Organism	Nocardia sp.	Nocardia sp.	MIC	=	0.00025	ug.mL-1	PMID[20624681]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500.0	nM	DOI[10.6019/CHEMBL1201861]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	<=	500.0	nM	DOI[10.6019/CHEMBL1201861]
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC50	=	1.0	ug.mL-1	PMID[11743742]
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC90	=	4.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	4.0	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	2.0	ug.mL-1	PMID[24571273]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	=	16.0	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	91.4	%	PMID[25644672]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	IZ	=	32.0	mm	PMID[9461657]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	IZ	=	25.0	mm	PMID[9461657]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MBC	=	0.009	mM	PubChem BioAssay data set
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	3000.0	nM	PMID[19770287]
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	Activity	=	29.7	%	PMID[21458113]
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	Activity	=	4.2	%	PMID[10924176]
NPT2911	Organism	Pseudomonas putida	Pseudomonas putida	MIC	>	32.0	ug.mL-1	DOI[10.1039/C0MD00267D]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	0.5	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT3496	Organism	Enterobacter	Enterobacter	Activity	=	2.0	%	PMID[22608675]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	4.0	ug.mL-1	PMID[20795741]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	16.0	ug.mL-1	PMID[20795741]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	64.0	ug.mL-1	PMID[18023934]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	<	2.0	ug.mL-1	PMID[18955520]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	4.0	ug.mL-1	PMID[1294697]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	MIC	>=	256.0	ug.mL-1	PMID[20350806]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	MIC	=	2.0	ug.mL-1	PMID[19928832]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	MIC	=	1.0	ug.mL-1	PMID[25479041]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	48.0	ug.mL-1	PMID[21477899]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	3.0	ug.mL-1	PMID[22858297]
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	Activity	=	8.3	%	PMID[6688830]
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	Activity	=	73.3	%	PMID[6688830]
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	MIC90	=	32.0	ug.mL-1	PubChem BioAssay data set
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	MIC50	=	8.0	ug.mL-1	PubChem BioAssay data set
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	0.78	ug.mL-1	PMID[19828313]
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	100.0	ug.mL-1	PMID[18955526]
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	1.56	ug.mL-1	PMID[18955526]
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	1.25	ug.mL-1	PMID[22381047]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	2.0	ug.mL-1	PMID[15165138]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	5.0	ug.mL-1	PMID[18447384]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	1.71	mmol/ml	DrugMatrix in vivo data: Hematology
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	8.0	ug.mL-1	PMID[20795741]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC50	>	128.0	ug.mL-1	PMID[19805554]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC90	>	128.0	ug.mL-1	PMID[19805554]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	>	32.0	ug.mL-1	PMID[20038618]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	4.0	ug.mL-1	PMID[20038618]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	0.9	ug.mL-1	PMID[19667291]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>=	64.0	ug.mL-1	PMID[18023934]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	<=	2.0	ug.mL-1	PMID[18955520]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	8.0	ug.mL-1	PMID[2016726]
NPT2905	Organism	Nocardia farcinica	Nocardia farcinica	MIC	>	1024.0	ug.mL-1	PMID[20585136]
NPT2905	Organism	Nocardia farcinica	Nocardia farcinica	MIC	=	64.0	ug.mL-1	PMID[12398531]
NPT2905	Organism	Nocardia farcinica	Nocardia farcinica	MIC	<	1.0	ug.mL-1	PMID[20585136]
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	MIC90	>	64.0	ug.mL-1	PMID[18077425]
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	MIC50	=	4.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	MIC90	=	8.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	MIC50	=	2.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	MIC50	>	256.0	ug.mL-1	Open TG-GATES in vivo data: Biochemistry
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	MIC90	>	256.0	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	64.0	ug.mL-1	PMID[18023934]
NPT2911	Organism	Pseudomonas putida	Pseudomonas putida	MIC	=	1.0	ug.mL-1	PubChem BioAssay data set
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Activity	=	59.0	%	PMID[20404121]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	MIC50	=	16.0	ug.mL-1	PMID[18355033]
NPT2894	Organism	Providencia rettgeri	Providencia rettgeri	MIC50	=	1.0	ug.mL-1	PubChem BioAssay data set
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	1.0	ug.mL-1	DOI[10.1016/S0960-894X(01)80927-6]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	MIC	>	0.5	ug.mL-1	PubChem BioAssay data set
NPT2894	Organism	Providencia rettgeri	Providencia rettgeri	MIC	=	0.5	ug.mL-1	PMID[23182091]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	0.5	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	MIC90	=	2.0	ug.mL-1	PMID[10924160]
NPT2894	Organism	Providencia rettgeri	Providencia rettgeri	MIC90	=	32.0	ug.mL-1	PMID[16643028]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	66.0	%	PMID[16417306]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	75.0	%	PMID[16417306]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	92.7	%	PMID[16417306]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	98.6	%	PMID[16417306]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	=	1.0	ug.mL-1	PMID[12350139]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	MIC50	=	0.5	ug.mL-1	PMID[23190013]
NPT2894	Organism	Providencia rettgeri	Providencia rettgeri	MIC50	=	2.0	ug.mL-1	PubChem BioAssay data set
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	MIC	=	0.25	ug.mL-1	PMID[24914738]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	Activity	=	48.0	%	PMID[19938815]
NPT2894	Organism	Providencia rettgeri	Providencia rettgeri	Activity	=	80.0	%	PMID[22512738]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	82.1	%	PMID[21719287]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	Activity	=	98.0	%	DrugMatrix in vitro pharmacology data
NPT2894	Organism	Providencia rettgeri	Providencia rettgeri	Activity	=	84.6	%	DrugMatrix in vitro pharmacology data
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	100.0	%	PMID[23398362]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	>	128.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	MIC90	>	128.0	ug.mL-1	PMID[12502314]
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC90	=	2.0	ug.mL-1	PMID[19721074]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	0.25	ug.mL-1	PMID[18725441]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	<=	0.5	ug.mL-1	PMID[18725441]
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	<=	0.03	ug.mL-1	PMID[18955515]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	1.0	ug.mL-1	PMID[18725441]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC90	=	8.0	ug.mL-1	PMID[18591277]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	=	64.0	ug.mL-1	PMID[26403929]
NPT1246	Organism	Salmonella	Salmonella	MIC90	=	8.0	ug.mL-1	PubChem BioAssay data set
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	2.6	%	PMID[25801154]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	0.0	%	PMID[17665951]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	6.7	%	PMID[25881827]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	1.9	%	PMID[24900468]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	2.4	%	PMID[9644053]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	28.6	%	PMID[12502332]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	81.0	%	PMID[21182258]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	83.3	%	PMID[21397370]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	78.9	%	PMID[21420867]
NPT1246	Organism	Salmonella	Salmonella	MIC50	=	2.0	ug.mL-1	PMID[18718695]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC50	=	2.0	ug.mL-1	PMID[18591277]
NPT1246	Organism	Salmonella	Salmonella	MIC	=	0.5	ug.mL-1	PubChem BioAssay data set
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	0.5	ug.mL-1	PMID[18591277]
NPT3599	Organism	Staphylococcus capitis	Staphylococcus capitis	MIC	=	0.5	ug.mL-1	PMID[26551342]
NPT5312	Organism	Staphylococcus warneri	Staphylococcus warneri	MIC	<	0.25	ug.mL-1	PMID[20930123]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	32.0	ug.mL-1	PMID[8350092]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	106.0	%	PMID[17844994]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	102.0	%	PMID[3210015]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	128.0	ug.mL-1	PMID[26331426]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	1.5	ug.mL-1	PMID[18838581]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	48.0	ug.mL-1	PMID[18838581]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	6.0	ug.mL-1	PMID[18838581]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	16.0	ug.mL-1	PMID[18838581]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	=	96.0	ug.mL-1	DOI[10.1007/s00044-009-9206-8]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	=	12.0	ug.mL-1	DOI[10.1039/C3MD00125C]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	=	32.0	ug.mL-1	PMID[19349520]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	95.0	%	PMID[23398362]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	69.0	%	PMID[23398362]
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	0.25	ug.mL-1	PMID[19423196]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MBC	=	1.0	ug ml-1	PubChem BioAssay data set
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MBC	=	2.0	ug ml-1	Open TG-GATES in vivo data: Hematology
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	73.0	%	PMID[21044847]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	99.0	%	PMID[21044847]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	12.0	ug.mL-1	PMID[1708405]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	78.4	%	PMID[15267229]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	48.0	%	PMID[12852746]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	4.9	%	DrugMatrix in vitro pharmacology data
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	20.0	%	PMID[17665951]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	50.0	%	PMID[17665951]
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	log10cfu	=	7.2	n.a.	PMID[19738016]
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	log10cfu	=	6.7	n.a.	PMID[19738016]
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	log10cfu	=	5.9	n.a.	PMID[19738016]
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	log10cfu	=	3.5	n.a.	PMID[19738016]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	>	64.0	ug.mL-1	PMID[19596870]
NPT5772	Organism	Enterobacter hormaechei	Enterobacter hormaechei	MIC	=	4.0	ug.mL-1	PMID[12398531]
NPT5772	Organism	Enterobacter hormaechei	Enterobacter hormaechei	MIC	=	8.0	ug.mL-1	PMID[20303767]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	12.0	ug.mL-1	PMID[10924160]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	1.0	ug.mL-1	PMID[24507923]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	MIC	<	1.0	ug.mL-1	PMID[25479041]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16.0	ug.mL-1	PMID[25856683]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	16.0	ug.mL-1	PMID[25856683]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	4.0	ug.mL-1	PMID[18077363]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	>	256.0	ug.mL-1	PMID[19581457]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	>	256.0	ug.mL-1	PMID[19581457]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	MIC	=	32.0	ug.mL-1	PMID[20739103]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	30.0	ug.mL-1	PMID[23746784]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	IZ	=	21.0	mm	PMID[2607352]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	IZ	=	21.0	mm	DrugMatrix in vitro pharmacology data
NPT564	Organism	Listeria monocytogenes	Listeria monocytogenes	IZ	=	20.0	mm	PMID[18077363]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	6.0	ug.mL-1	PubChem BioAssay data set
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	6.0	ug.mL-1	PMID[2453615]
NPT564	Organism	Listeria monocytogenes	Listeria monocytogenes	MIC	=	6.0	ug.mL-1	DOI[10.1016/S0960-894X(97)10101-9]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	IZ	=	18.0	mm	DrugMatrix in vivo data: Pathology
NPT1228	Organism	Streptococcus pyogenes	Streptococcus pyogenes	IZ	=	20.0	mm	PMID[23200246]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	>	64.0	ug.mL-1	PMID[26403929]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	IZ	=	11.0	mm	PMID[27096049]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (acute)	=	0.0	%	PMID[15646539]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2000.0	nM	PMID[3039137]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	32000.0	nM	PMID[26091285]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	32000.0	nM	PMID[26091285]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	8000.0	nM	PubChem BioAssay data set
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	71720.0	nM	PMID[20558060]
NPT3888	Organism	Micrococcus flavus	Micrococcus flavus	MIC	=	3420.0	nM	PMID[15658872]
NPT564	Organism	Listeria monocytogenes	Listeria monocytogenes	MIC	=	9.4	ug.mL-1	PMID[25316316]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	37.5	ug.mL-1	PMID[17850214]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	2.3	ug.mL-1	PMID[16499313]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC>99	=	0.5	uM	PMID[28835350]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC>99	=	2.0	uM	PMID[26948407]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC>99	=	1.0	uM	PMID[28835350]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC>99	>	32.0	uM	PMID[28835350]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	3900.0	nM	PMID[27769670]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000.0	nM	PMID[27907875]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	160.0	nM	PMID[27687968]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	IC90	=	80.0	nM	PMID[25129868]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	IC50	=	70.0	nM	PMID[27687968]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	0.625	ug.mL-1	PMID[28400238]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	5.0	ug.mL-1	PMID[28400238]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	IC50	=	80.0	nM	PMID[29202408]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	IC90	=	90.0	nM	PMID[29202408]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC>95	=	0.0625	uM	PMID[30742437]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MBC>99.9	=	0.125	uM	PMID[30742437]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4.0	ug.mL-1	PMID[31534654]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	400.0	nM	PMID[30803803]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1600.0	nM	PMID[30803803]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	700.0	nM	PMID[30803803]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1700.0	nM	PMID[30803803]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	400.0	nM	PMID[30803803]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	32.0	ug.mL-1	PMID[24164206]
NPT5772	Organism	Enterobacter hormaechei	Enterobacter hormaechei	MIC	=	0.2	ug.mL-1	PMID[33296194]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	30.0	%	PMID[27687968]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	7000.0	nM	PMID[33582576]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	1830.0	nM	PMID[32950907]
NPT29807	Organism	Mycobacteroides abscessus	Mycobacteroides abscessus	GI	n.a.	n.a.	n.a.	PMID[38665829]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.22	ug.mL-1	PMID[35486992]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.24	ug.mL-1	PMID[35486992]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC>99	>	32.0	uM	PMID[38157261]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.5	ug.mL-1	PMID[38665829]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC>99	=	0.5	uM	PMID[38157261]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC>99	=	2.0	uM	PMID[38157261]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.91	ug.mL-1	PMID[35486992]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	23.13	ug.mL-1	PMID[35059125]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.14	ug.mL-1	PMID[35059125]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC>99	=	1.0	uM	PMID[38157261]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.25	ug.mL-1	PMID[35486992]
NPT29218	Organism	Mycobacteroides chelonae	Mycobacteroides chelonae	GI	n.a.	n.a.	n.a.	PMID[38665829]
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	3900.0	nM	PMID[36037791]
NPT29807	Organism	Mycobacteroides abscessus	Mycobacteroides abscessus	MIC	=	1000.0	nM	PMID[36037791]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.32	ug.mL-1	PMID[35059125]
NPT29807	Organism	Mycobacteroides abscessus	Mycobacteroides abscessus	MIC50	=	4.3	ug.mL-1	PMID[35307568]
NPT29807	Organism	Mycobacteroides abscessus	Mycobacteroides abscessus	MIC50	=	2.3	ug.mL-1	PMID[35307568]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.19	ug.mL-1	PMID[35486992]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	=	0.24	ug.mL-1	PMID[35307568]
NPT29807	Organism	Mycobacteroides abscessus	Mycobacteroides abscessus	MIC50	=	7400.0	nM	PMID[33071055]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	25.0	ug.mL-1	PMID[35059125]
NPT29807	Organism	Mycobacteroides abscessus	Mycobacteroides abscessus	MIC90	=	5.9	ug.mL-1	PMID[35307568]
NPT29807	Organism	Mycobacteroides abscessus	Mycobacteroides abscessus	MIC90	=	3.4	ug.mL-1	PMID[35307568]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.37	ug.mL-1	PMID[35307568]
NPT29807	Organism	Mycobacteroides abscessus	Mycobacteroides abscessus	MIC50	=	3900.0	nM	PMID[33071055]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.12	ug.mL-1	PMID[28628823]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	512.0	ug.mL-1	PMID[37122541]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	IZ	=	18.0	mm	PMID[32971428]
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2.0	ug.mL-1	PMID[36459759]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	2500.0	nM	PMID[38124427]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (moderate)	=	6.0	n.a.	PMID[15646539]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (moderate)	=	15.3	%	PMID[15646539]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (granulomatous hepatitis)	=	0.0	n.a.	PMID[15646539]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (benign tumour)	=	0.0	n.a.	PMID[15646539]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	1.0	ug.mL-1	PMID[2374153]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	4.0	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	2.0	ug.mL-1	PMID[22194678]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	8.0	ug.mL-1	PMID[8388467]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	256.0	ug.mL-1	PMID[9548847]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	4.0	ug.mL-1	PMID[20308368]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	=	64.0	ug.mL-1	PMID[17665951]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	32.0	ug.mL-1	PMID[22858297]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	64.0	ug.mL-1	DOI[10.1039/C2MD20300F]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	32.0	ug.mL-1	PMID[20614907]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	128.0	ug.mL-1	PMID[18955520]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	>	64.0	ug.mL-1	PMID[17665951]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	1.0	ug.mL-1	PMID[26476666]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	2.0	ug.mL-1	PMID[20194700]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	16.0	ug.mL-1	PMID[17353252]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.5	ug.mL-1	PMID[18955520]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC	=	64.0	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	0.0	%	PMID[14510593]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	6.0	%	PMID[18417256]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	32.0	%	PMID[18681480]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	3.0	%	Open TG-GATES in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	37.0	%	Open TG-GATES in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	48.0	%	Open TG-GATES in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	36.0	%	Open TG-GATES in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	34.0	%	Open TG-GATES in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	31.0	%	Open TG-GATES in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	44.0	%	Open TG-GATES in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	69.0	%	Open TG-GATES in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	46.0	%	Open TG-GATES in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	8.0	%	PMID[25052206]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	5.0	%	PMID[24484240]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	11.0	%	PMID[24484240]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	35.0	%	PMID[24484240]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	90.9	%	DailyMed
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	82.0	%	DrugMatrix in vitro pharmacology data
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	95.6	%	DrugMatrix in vitro pharmacology data
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	3.0	ug.mL-1	PMID[17665951]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	12.0	ug.mL-1	PMID[15787444]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	256.0	ug.mL-1	PMID[10075797]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	256.0	ug.mL-1	PMID[9548847]
NPT6018	Organism	Nocardia otitidiscaviarum	Nocardia otitidiscaviarum	MIC	=	0.001	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	4.0	ug.mL-1	PMID[15165138]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	8.0	ug.mL-1	PMID[26287401]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	16.0	ug.mL-1	PMID[18077425]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	1.0	ug.mL-1	PMID[18070975]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	IZ	=	23.0	mm	PubChem BioAssay data set
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC50	=	16.0	ug.mL-1	PMID[22182927]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC90	=	32.0	ug.mL-1	PMID[22182927]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC	>	128.0	ug.mL-1	PMID[17576842]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC	=	64.0	ug.mL-1	PMID[17517838]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC	=	32.0	ug.mL-1	PMID[2724305]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	<=	8.0	ug.mL-1	PMID[25443644]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC90	=	16.0	ug.mL-1	PMID[25443644]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	4.0	%	PMID[19674906]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	7.0	%	DrugMatrix in vitro pharmacology data
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	=	2.0	ug.mL-1	PMID[25599951]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC90	=	8.0	ug.mL-1	PMID[25599951]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	98.1	%	PMID[25599951]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	16.0	ug.mL-1	PMID[18077425]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	19.0	%	DrugMatrix in vitro pharmacology data
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC50	=	4.0	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC80	=	8.0	ug.mL-1	PMID[10924160]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	32.0	ug.mL-1	PMID[11374952]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	IZ	=	30.0	mm	PMID[9461657]
NPT19	Organism	Escherichia coli	Escherichia coli	IZ	=	30.0	mm	PMID[9461657]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IZ	=	25.0	mm	PMID[20594858]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	IZ	=	23.0	mm	PMID[20594858]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC	=	0.012	mM	DOI[10.1016/S0960-894X(97)00380-6]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	6000.0	nM	PubChem BioAssay data set
NPT19	Organism	Escherichia coli	Escherichia coli	MBC	=	0.006	mM	PubChem BioAssay data set
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	3000.0	nM	PMID[19770287]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	IZ	=	33.0	mm	PMID[17665951]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	8.0	ug ml-1	PMID[8411013]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	512.0	ug.mL-1	PMID[20166671]
NPT4080	Organism	Acinetobacter sp.	Acinetobacter sp.	MIC	>	32.0	ug.mL-1	PMID[11141096]
NPT4080	Organism	Acinetobacter sp.	Acinetobacter sp.	MIC	=	32.0	ug.mL-1	PMID[11141096]
NPT2904	Organism	Streptococcus equinus	Streptococcus equinus	MIC	=	64.0	ug.mL-1	PMID[19620332]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	8.0	ug.mL-1	PMID[20738102]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.5	ug.mL-1	PMID[15165138]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	=	32.0	ug.mL-1	PMID[18077425]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	>=	250.0	ug.mL-1	DOI[10.1039/C3MD00097D]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	48.0	ug.mL-1	PMID[25856683]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	<	2.0	ug.mL-1	PMID[22194678]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	16.0	ug.mL-1	PMID[26479031]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	<=	0.5	ug.mL-1	PMID[15165138]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	128.0	ug.mL-1	PMID[22137458]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	1.7	%	PMID[11421749]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	93.3	%	PubChem BioAssay data set
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	9.0	%	PMID[24767839]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.75	ug.mL-1	PMID[18434145]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	1.5	ug.mL-1	PMID[21419530]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	16.0	ug.mL-1	PMID[24216090]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.13	ug.mL-1	DrugMatrix in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	32.0	ug.mL-1	PMID[22194678]
NPT3497	Organism	Klebsiella sp.	Klebsiella sp.	MIC90	>	32.0	ug.mL-1	PMID[226705]
NPT3497	Organism	Klebsiella sp.	Klebsiella sp.	MIC50	=	16.0	ug.mL-1	PMID[226705]
NPT3497	Organism	Klebsiella sp.	Klebsiella sp.	Activity	=	13.3	%	DOI[10.1016/S0960-894X(00)80048-7]
NPT3497	Organism	Klebsiella sp.	Klebsiella sp.	Activity	=	53.3	%	PMID[6688830]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	100.0	ug.mL-1	PMID[10346940]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	50.0	ug.mL-1	PMID[24261937]
NPT5774	Organism	Citrobacter amalonaticus	Citrobacter amalonaticus	MIC	>	128.0	ug.mL-1	PMID[26035018]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	128.0	ug.mL-1	PMID[18955520]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	0.5	ug.mL-1	PMID[10757713]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	2.0	ug.mL-1	DrugMatrix in vivo data: Hematology
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	=	4.0	ug.mL-1	PMID[8759172]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	=	2.0	ug.mL-1	PMID[20086162]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	1.0	ug.mL-1	PMID[12662097]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	2.0	ug.mL-1	PMID[12662097]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC	>	512.0	ug.mL-1	PMID[10096857]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	=	1.71	mmol/ml	DrugMatrix in vivo data: Hematology
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC50	=	27.32	mmol/ml	DrugMatrix in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	64.0	ug.mL-1	PMID[8699189]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	BBC	=	4.0	ug ml-1	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	BBC	=	8.0	ug ml-1	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	BBC	=	16.0	ug ml-1	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	BBC	=	64.0	ug ml-1	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC50	=	16.0	ug.mL-1	PMID[23200246]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC50	=	128.0	ug.mL-1	PMID[19124664]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC50	=	8.0	ug.mL-1	PMID[23268742]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC50	=	1.0	ug.mL-1	PMID[14980653]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	>	128.0	ug.mL-1	PubChem BioAssay data set
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC90	>	128.0	ug.mL-1	PMID[23848163]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC90	=	16.0	ug.mL-1	PMID[22172700]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC90	=	4.0	ug.mL-1	PMID[22194678]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	18.6	%	DrugMatrix in vitro pharmacology data
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	<	4.0	ug.mL-1	PMID[15165138]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	39.0	%	PMID[17606689]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	45.0	%	PMID[17988099]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.9	ug.mL-1	PMID[20547814]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	1.9	ug.mL-1	PMID[18458127]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC	=	2.0	ug.mL-1	PMID[22901896]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MBC	=	64.0	ug ml-1	PMID[22901896]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MBC	=	32.0	ug ml-1	PMID[22901896]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MBC	=	128.0	ug ml-1	PMID[25479041]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	<=	2.0	ug.mL-1	PMID[22194678]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	64.0	ug.mL-1	DOI[10.1039/C2MD20300F]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	IZ	<	20.0	mm	PMID[18341287]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>=	128.0	ug.mL-1	PMID[18955520]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC50	=	8.0	ug.mL-1	PMID[22037378]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	64.0	ug.mL-1	PMID[18077363]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	50.0	%	PMID[21123165]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	24.0	ug.mL-1	PubChem BioAssay data set
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	128.0	ug.mL-1	PMID[22137458]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	1.6	ug.mL-1	PMID[18183025]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	25.0	ug.mL-1	PMID[12662097]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	3.2	ug.mL-1	PMID[18183025]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC50	=	128.0	ug.mL-1	PMID[25064347]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC50	=	4.0	ug.mL-1	PMID[25089810]
NPT3699	Organism	Pseudomonas sp.	Pseudomonas sp.	MIC50	>	128.0	ug.mL-1	PMID[26287401]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC50	=	1.0	ug.mL-1	PMID[26034885]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	=	1.0	ug.mL-1	PMID[23327668]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	>	32.0	ug.mL-1	PMID[18077425]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	1.0	ug.mL-1	PMID[2374153]
NPT3699	Organism	Pseudomonas sp.	Pseudomonas sp.	MIC	>	2.0	ug.mL-1	PMID[2374153]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	2.0	ug.mL-1	PMID[20194700]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC	>	1.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	0.5	ug.mL-1	PMID[18955520]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC90	=	2.0	ug.mL-1	PMID[19654408]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC90	=	2.0	ug.mL-1	PMID[19654408]
NPT3189	Organism	Haemophilus parainfluenzae	Haemophilus parainfluenzae	MIC90	=	8.0	ug.mL-1	PMID[25062007]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC50	=	0.5	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT3189	Organism	Haemophilus parainfluenzae	Haemophilus parainfluenzae	MIC50	=	4.0	ug.mL-1	PMID[12502331]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	<=	0.03	ug.mL-1	PMID[12443782]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.06	ug.mL-1	PMID[11806727]
NPT3189	Organism	Haemophilus parainfluenzae	Haemophilus parainfluenzae	MIC	=	2.0	ug.mL-1	PMID[18597527]
NPT3699	Organism	Pseudomonas sp.	Pseudomonas sp.	MIC90	=	16.0	ug.mL-1	PMID[26951751]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC90	=	2.0	ug.mL-1	PMID[17070063]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	53.7	%	PMID[9834146]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	59.5	%	PMID[16417306]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	97.0	%	PubChem BioAssay data set
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	98.5	%	PMID[16417306]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC90	=	2.0	ug.mL-1	PMID[12350139]
NPT3699	Organism	Pseudomonas sp.	Pseudomonas sp.	MIC50	=	4.0	ug.mL-1	Open TG-GATES in vivo data: Biochemistry
NPT3699	Organism	Pseudomonas sp.	Pseudomonas sp.	MIC	=	0.5	ug.mL-1	PMID[18849971]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.06	ug.mL-1	PMID[24914738]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC	=	0.5	ug.mL-1	PMID[25226228]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	Activity	=	73.1	%	PMID[17988094]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	Activity	=	80.6	%	PMID[8021914]
NPT3699	Organism	Pseudomonas sp.	Pseudomonas sp.	Activity	=	7.7	%	PMID[19581457]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	85.3	%	PMID[19938815]
NPT3495	Organism	Morganella morganii	Morganella morganii	Activity	=	83.3	%	PMID[14592517]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	93.0	%	PMID[21737271]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	Activity	=	98.8	%	PMID[18070971]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	Activity	=	100.0	%	PubChem BioAssay data set
NPT3699	Organism	Pseudomonas sp.	Pseudomonas sp.	Activity	=	90.9	%	PubChem BioAssay data set
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	100.0	%	PubChem BioAssay data set
NPT3495	Organism	Morganella morganii	Morganella morganii	Activity	=	96.0	%	PMID[23398362]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	100.0	%	PMID[18494522]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC90	=	4.0	ug.mL-1	PubChem BioAssay data set
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC90	=	4.0	ug.mL-1	PMID[15711537]
NPT3699	Organism	Pseudomonas sp.	Pseudomonas sp.	MIC90	>	128.0	ug.mL-1	PMID[20038128]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC90	=	128.0	ug.mL-1	PMID[20038128]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC90	=	64.0	ug.mL-1	PMID[19916528]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC90	>	128.0	ug.mL-1	PMID[23398362]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Ratio	=	13.0	n.a.	PMID[12350151]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Ratio	=	20.0	n.a.	PMID[10757717]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC50	=	2.0	ug.mL-1	DOI[10.1016/j.cropro.2007.04.007]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC90	=	8.0	ug.mL-1	PMID[19349512]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	<=	2.0	ug.mL-1	PMID[20194700]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	512.0	ug.mL-1	PMID[17336532]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC50	=	16.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC50	=	2.0	ug.mL-1	PubChem BioAssay data set
NPT766	Organism	Proteus vulgaris	Proteus vulgaris	MIC90	=	8.0	ug.mL-1	PMID[18722127]
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC90	=	8.0	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	51.0	%	PMID[20627740]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	0.0	%	PMID[9644053]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	12.5	%	PMID[11520222]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	81.0	%	PMID[21182258]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	83.3	%	PMID[22694318]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	78.9	%	PMID[10843574]
NPT766	Organism	Proteus vulgaris	Proteus vulgaris	MIC50	=	2.0	ug.mL-1	PMID[18557621]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC50	=	2.0	ug.mL-1	PMID[21955940]
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC	=	0.5	ug.mL-1	PMID[19222165]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC	>	0.5	ug.mL-1	PMID[18443128]
NPT766	Organism	Proteus vulgaris	Proteus vulgaris	MIC	=	0.5	ug.mL-1	PMID[16472241]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC	=	1.0	ug.mL-1	Open TG-GATES in vivo data: Hematology
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	0.8	ug.mL-1	PMID[26551342]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	4.0	ug.mL-1	PMID[23354072]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	8.0	ug.mL-1	PMID[26564265]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.25	ug.mL-1	PMID[18955520]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	32.0	ug.mL-1	PMID[22858297]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	<=	0.03	ug.mL-1	PMID[23755850]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	98.0	%	PMID[23398362]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	71.0	%	PMID[23398362]
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	Activity	=	100.0	%	PMID[23398362]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	96.0	%	PMID[16933872]
NPT5770	Organism	Pasteurella sp.	Pasteurella sp.	Activity	=	31.0	%	PMID[23992864]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	Activity	=	31.0	%	PMID[16933872]
NPT4080	Organism	Acinetobacter sp.	Acinetobacter sp.	Activity	=	31.0	%	PMID[16933872]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.25	ug.mL-1	PMID[18955526]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.5	ug.mL-1	PMID[24900509]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>=	32.0	ug.mL-1	PMID[22858297]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	1.0	%	PubChem BioAssay data set
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC	=	4.0	ug.mL-1	PMID[19805554]
NPT19	Organism	Escherichia coli	Escherichia coli	MBC	=	4.0	ug ml-1	DrugMatrix in vitro pharmacology data
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC	=	2.0	ug ml-1	PMID[23734701]
NPT19	Organism	Escherichia coli	Escherichia coli	MBC	=	16.0	ug ml-1	DrugMatrix in vitro pharmacology data
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC	=	32.0	ug ml-1	PMID[12398531]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC	=	64.0	ug ml-1	PMID[12398531]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC	=	4.0	ug ml-1	PubChem BioAssay data set
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FC	>=	4.0	n.a.	PMID[10924160]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	6.0	ug.mL-1	PMID[18625769]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	87.0	%	PubChem BioAssay data set
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	Activity	=	86.0	%	PMID[21044847]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	85.0	%	PMID[12444692]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	<=	0.5	ug.mL-1	PMID[18955520]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	17.0	%	PMID[14510593]
NPT3495	Organism	Morganella morganii	Morganella morganii	Activity	=	100.0	%	PMID[17665951]
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC	=	2.0	ug.mL-1	PMID[12762801]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	128.0	ug.mL-1	PMID[2374153]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	>	128.0	ug.mL-1	PMID[19654408]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	64.0	ug.mL-1	PMID[8699189]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.15	ug.mL-1	PMID[26292628]
NPT19	Organism	Escherichia coli	Escherichia coli	Ratio	=	2.0	n.a.	PMID[26292628]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	64.0	ug.mL-1	PMID[20361799]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	64.0	ug.mL-1	PMID[20361799]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	=	16.0	ug.mL-1	PMID[21282406]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC90	=	32.0	ug.mL-1	PMID[24168147]
NPT3497	Organism	Klebsiella sp.	Klebsiella sp.	MIC50	=	32.0	ug.mL-1	PMID[25453799]
NPT3497	Organism	Klebsiella sp.	Klebsiella sp.	MIC90	>	64.0	ug.mL-1	PMID[25453799]
NPT4080	Organism	Acinetobacter sp.	Acinetobacter sp.	MIC50	>	64.0	ug.mL-1	PubChem BioAssay data set
NPT4080	Organism	Acinetobacter sp.	Acinetobacter sp.	MIC90	>	64.0	ug.mL-1	PMID[25647077]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	>	64.0	ug.mL-1	PMID[18077363]
NPT4200	Organism	Serratia liquefaciens	Serratia liquefaciens	MIC	=	4.0	ug.mL-1	PMID[11206438]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	30.0	ug.mL-1	PMID[23746784]
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC	=	30.0	ug.mL-1	PMID[23746784]
NPT6506	Organism	Enterobacter gergoviae	Enterobacter gergoviae	MIC	=	2.0	ug.mL-1	PMID[23354070]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	13.0	ug.mL-1	PMID[2016706]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	13.0	ug.mL-1	PMID[20570526]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	18.0	ug.mL-1	PMID[20350806]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	18.0	ug.mL-1	PMID[20156689]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	14.0	ug.mL-1	PMID[18610999]
NPT19	Organism	Escherichia coli	Escherichia coli	IZ	=	22.0	mm	PMID[26358281]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	IZ	=	22.0	mm	PMID[23022281]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IZ	=	20.0	mm	PMID[12646019]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IZ	=	17.0	mm	PMID[26938998]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IZ	=	19.0	mm	PMID[10346946]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	6.0	ug.mL-1	PMID[16309313]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	12.0	ug.mL-1	PMID[15990295]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	50.0	ug.mL-1	PMID[16989519]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100.0	ug.mL-1	PMID[10346940]
NPT19	Organism	Escherichia coli	Escherichia coli	IZ	=	14.0	mm	PMID[17850214]
NPT19	Organism	Escherichia coli	Escherichia coli	IZ	=	16.2	mm	PMID[9358643]
NPT19	Organism	Escherichia coli	Escherichia coli	IZ	=	20.0	mm	PMID[22652254]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC50	=	32.0	ug.mL-1	PMID[20630628]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC90	>	64.0	ug.mL-1	PMID[24900361]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	IZ	=	22.1	mm	PMID[18077363]
NPT19	Organism	Escherichia coli	Escherichia coli	IZ	=	21.27	mm	PMID[16297615]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	IZ	=	17.0	mm	PubChem BioAssay data set
NPT19	Organism	Escherichia coli	Escherichia coli	IZ	=	17.0	mm	DOI[10.6019/CHEMBL1201861]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IZ	=	18.0	mm	PMID[23316950]
NPT4080	Organism	Acinetobacter sp.	Acinetobacter sp.	MIC50	=	4.0	ug.mL-1	PMID[25647077]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	=	8.0	ug.mL-1	PMID[25443644]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC90	=	64.0	ug.mL-1	PMID[23327668]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC50	>	64.0	ug.mL-1	PMID[18547683]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	IZ	=	25.0	mm	PubChem BioAssay data set
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	IZ	=	24.0	mm	PubChem BioAssay data set
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	IZ	=	15.0	mm	PMID[25600409]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC>90	=	1.8	ug ml-1	PMID[24224794]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log10CFU/g	=	2.0	n.a.	PMID[25927406]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IZ	=	16.0	mm	PMID[20061160]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	IZ	=	16.0	mm	PMID[20061160]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	18780.0	nM	PubChem BioAssay data set
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	8540.0	nM	PMID[17400457]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	85380.0	nM	DrugMatrix in vitro pharmacology data
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	256.0	ug.mL-1	PMID[18955520]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	512.0	ug.mL-1	PMID[20166671]
NPT766	Organism	Proteus vulgaris	Proteus vulgaris	MIC	=	512.0	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	=	256.0	ug.mL-1	PMID[21667925]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	19000.0	nM	PMID[17118653]
NPT3145	Organism	Bacillus subtilis subsp. spizizenii ATCC 6633	Bacillus subtilis subsp. spizizenii ATCC 6633	MIC	=	72000.0	nM	PMID[12762801]
NPT3165	Organism	Micrococcus luteus NCTC 2665	Micrococcus luteus NCTC 2665	MIC	=	3000.0	nM	PMID[24424132]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	9000.0	nM	PMID[20547799]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	85000.0	nM	DrugMatrix in vitro pharmacology data
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	>	250.0	ug.mL-1	DOI[10.1039/C3MD00097D]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	4.5	ug.mL-1	PMID[28214232]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	EC50	=	3.8	ug.mL-1	PMID[28214232]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	3.6	deltalog10CFU	PMID[28248499]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	2.5	ug.mL-1	PMID[28400238]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	2.5	ug.mL-1	PMID[28400238]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	=	0.39	ug.mL-1	PMID[28400238]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.312	ug.mL-1	PMID[28400238]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	2.5	ug.mL-1	PMID[28400238]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	14000.0	nM	PMID[29019685]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	Activity	<	50.0	%	PMID[30388360]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC>95	=	0.0625	uM	PMID[30742437]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC>95	=	0.125	uM	PMID[30742437]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC>95	=	0.0625	uM	PMID[30742437]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC>95	>	64.0	uM	PMID[30742437]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC>95	=	0.25	uM	PMID[30742437]
NPT19	Organism	Escherichia coli	Escherichia coli	MBC>99.9	=	0.125	uM	PMID[30742437]
NPT19	Organism	Escherichia coli	Escherichia coli	MBC>99.9	=	0.0625	uM	PMID[30742437]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC>99.9	=	0.25	uM	PMID[30742437]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC>99.9	=	0.125	uM	PMID[30742437]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC>99.9	>	64.0	uM	PMID[30742437]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	32.0	ug.mL-1	PMID[22194678]
NPT5485	Organism	Mycobacterium leprae	Mycobacterium leprae	Activity	=	97.3	%	PMID[31103404]
NPT5485	Organism	Mycobacterium leprae	Mycobacterium leprae	Activity	=	96.0	%	PMID[31103404]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.8	ug.mL-1	PMID[33296194]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	3400.0	nM	PMID[33582576]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	5000.0	nM	PMID[33582576]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	3660.0	nM	PMID[32950907]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	5000.0	nM	PMID[38124427]
NPT5774	Organism	Citrobacter amalonaticus	Citrobacter amalonaticus	MIC	>	512.0	ug.mL-1	PMID[37122541]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	GI	n.a.	n.a.	n.a.	PMID[38362867]
NPT28561	Organism	Mycolicibacterium fortuitum	Mycolicibacterium fortuitum	GI	n.a.	n.a.	n.a.	PMID[38665829]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	IZ	=	17.0	mm	PMID[32971428]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IZ	=	20.0	mm	PMID[32971428]
NPT28513	Organism	Mycolicibacterium smegmatis	Mycolicibacterium smegmatis	MIC	<=	250.0	nM	PMID[36037791]
NPT19	Organism	Escherichia coli	Escherichia coli	IZ	=	17.0	mm	PMID[32971428]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	512.0	ug.mL-1	PMID[37122541]
NPT25056	Cell line	BMDM	n.a.	CC50	>	90.0	ug.mL-1	PMID[35307568]
NPT2	Others	Unspecified	n.a.	Potency	n.a.	23710.1	nM	PMID[21377877]
NPT2	Others	Unspecified	n.a.	Potency	n.a.	105.9	nM	PMID[7562925]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	2.0	ug.mL-1	PMID[2016706]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	8.0	ug.mL-1	PMID[20155971]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	1.0	ug.mL-1	PMID[2821258]
NPT2	Others	Unspecified	n.a.	IC50	=	1020.0	nM	DOI[10.6019/CHEMBL1201861]
NPT2	Others	Unspecified	n.a.	Inhibition	=	43.0	%	DOI[10.6019/CHEMBL1201861]
NPT2	Others	Unspecified	n.a.	IC50	=	160.0	nM	DOI[10.6019/CHEMBL1201861]
NPT2	Others	Unspecified	n.a.	Inhibition	=	85.0	%	DOI[10.6019/CHEMBL1201861]
NPT2	Others	Unspecified	n.a.	Inhibition	=	0.0	%	DOI[10.6019/CHEMBL1201861]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	16.0	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	16.0	ug.mL-1	PMID[18183025]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	=	32.0	ug.mL-1	PMID[10217729]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	128.0	ug.mL-1	PMID[16792413]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	64.0	ug.mL-1	PMID[16792413]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	>	128.0	ug.mL-1	PMID[16792413]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC50	=	32.0	ug.mL-1	PMID[18161942]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC90	>	32.0	ug.mL-1	PMID[17629328]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Activity	=	36.0	%	PMID[12036352]
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC50	=	8.0	ug.mL-1	PMID[22705001]
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC90	=	8.0	ug.mL-1	PMID[22705001]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	<=	8.0	ug.mL-1	PubChem BioAssay data set
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	256.0	ug.mL-1	PMID[19805572]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	8.0	ug.mL-1	PubChem BioAssay data set
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	2.0	ug.mL-1	PMID[17189664]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	4.0	ug.mL-1	PMID[22130133]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	1.0	ug.mL-1	PMID[19105653]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	128.0	ug.mL-1	PMID[22182577]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	64.0	ug.mL-1	PMID[18077425]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	256.0	ug.mL-1	PMID[19805572]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	32.0	ug.mL-1	PMID[21377877]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	32.0	ug.mL-1	PMID[21377877]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	<=	2.0	ug.mL-1	PMID[17189664]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	3.0	ug.mL-1	PubChem BioAssay data set
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	12.0	ug.mL-1	PMID[15270564]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	512.0	ug.mL-1	PMID[20350806]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	2.0	ug.mL-1	PMID[15104490]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1.75	ug.mL-1	PMID[18955526]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	=	0.5	ug.mL-1	PMID[8254346]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	>	128.0	ug.mL-1	PMID[17502402]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	>	128.0	ug.mL-1	PMID[26035018]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	>	256.0	ug.mL-1	PMID[19482481]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	=	1.0	ug.mL-1	PMID[20056520]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	6.0	ug.mL-1	PMID[15679321]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	96.0	ug.mL-1	PMID[20684562]
NPT1209	Organism	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC	=	0.9	ug.mL-1	PubChem BioAssay data set
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC50	>	128.0	ug.mL-1	PMID[12608846]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	MIC50	=	32.0	ug.mL-1	PMID[22037378]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC50	=	16.0	ug.mL-1	PMID[16562846]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	>	0.5	ug.mL-1	PMID[12762801]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	MIC	=	1.0	ug.mL-1	PMID[9249968]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	>	1.0	ug.mL-1	PMID[20056520]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC90	=	2.0	ug.mL-1	PMID[10579870]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	MIC90	=	2.0	ug.mL-1	PMID[26291037]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC90	=	2.0	ug.mL-1	PMID[20547814]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC50	=	1.0	ug.mL-1	PMID[9014350]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	MIC50	=	1.0	ug.mL-1	PubChem BioAssay data set
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC50	=	1.0	ug.mL-1	DOI[10.1007/s00044-013-0757-3]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	MIC	=	0.5	ug.mL-1	PMID[9873651]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	<=	0.03	ug.mL-1	DOI[10.1007/s00044-011-9964-y]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	Activity	=	30.0	%	PubChem BioAssay data set
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	Activity	=	35.7	%	PMID[22694318]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	Activity	=	55.0	%	PMID[17958396]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	Activity	=	96.3	%	PMID[10217714]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	Activity	=	100.0	%	PMID[22749189]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	Activity	=	100.0	%	PMID[23398362]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC90	=	64.0	ug.mL-1	PMID[17587585]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	MIC90	=	64.0	ug.mL-1	PMID[25978960]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC90	>	128.0	ug.mL-1	PMID[22032697]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MBC	=	8.0	mg/L	PMID[18163584]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Activity	=	0.55	/hr	PMID[19282186]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Activity	=	6.62	10'8CFU/ml	PMID[19459694]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Activity	=	27.81	/hr	PMID[18163584]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	C50k	=	1.56	mg/L	PMID[18725438]
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC50	=	1.0	ug.mL-1	PMID[22694318]
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC90	=	16.0	ug.mL-1	PMID[17288478]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC50	=	64.0	ug.mL-1	DrugMatrix in vivo data: Pathology
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC90	=	125.0	ug.mL-1	PMID[19928832]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC50	=	16.0	ug.mL-1	PubChem BioAssay data set
NPT1209	Organism	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC50	=	16.0	ug.mL-1	PMID[17420206]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC50	=	2.0	ug.mL-1	PubChem BioAssay data set
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC90	=	8.0	ug.mL-1	PMID[19332671]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC90	>	128.0	ug.mL-1	PMID[18500841]
NPT1209	Organism	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC90	>	128.0	ug.mL-1	PMID[22472167]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC90	=	8.0	ug.mL-1	PMID[16040241]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	<=	0.5	ug.mL-1	PMID[17711347]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	128.0	ug.mL-1	PMID[22182577]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	0.5	ug.mL-1	PMID[17711347]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC50	=	8.0	ug.mL-1	PMID[18800848]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Activity	=	53.0	%	PubChem BioAssay data set
NPT2	Others	Unspecified	n.a.	Ratio	=	2.0	n.a.	PMID[19860383]
NPT2	Others	Unspecified	n.a.	Ratio	=	1.0	n.a.	DOI[10.6019/CHEMBL1201861]
NPT2	Others	Unspecified	n.a.	Ratio	=	0.125	n.a.	PMID[24035341]
NPT2	Others	Unspecified	n.a.	Ratio	=	0.5	n.a.	PMID[21493075]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC50	=	2.0	ug.mL-1	PMID[22264752]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	=	0.5	ug.mL-1	PMID[23957453]
NPT1209	Organism	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC	>	0.5	ug.mL-1	DrugMatrix in vitro pharmacology data
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	0.5	ug.mL-1	PMID[17711347]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	0.5	ug.mL-1	PMID[12762801]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	Activity	=	100.0	%	PMID[23992864]
NPT1209	Organism	Pseudomonas fluorescens	Pseudomonas fluorescens	Activity	=	31.0	%	PMID[16933872]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	Activity	=	83.0	%	PMID[23327759]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC50	>	128.0	ug.mL-1	PMID[26091285]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Activity	=	28.6	%	DOI[10.1007/s00044-010-9440-0]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Activity	=	71.4	%	Open TG-GATES in vivo data: Biochemistry
NPT1101	Organism	Staphylococcus aureus subsp. aureus RN4220	Staphylococcus aureus subsp. aureus RN4220	MIC	=	4.0	ug.mL-1	PMID[17503850]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	1.5	ug.mL-1	PubChem BioAssay data set
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	24.0	ug.mL-1	PMID[8254346]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	48.0	ug.mL-1	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.5	ug.mL-1	PMID[22194678]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Activity	=	36.7	%	PMID[23327794]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Ratio	=	1.0	n.a.	Open TG-GATES in vivo data: Hematology
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	>=	64.0	ug.mL-1	PMID[10217729]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	<=	2.0	ug.mL-1	PMID[10217729]
NPT5299	Organism	Staphylococcus sp.	Staphylococcus sp.	MIC50	=	16.0	ug.mL-1	PMID[20071056]
NPT5299	Organism	Staphylococcus sp.	Staphylococcus sp.	MIC90	>	64.0	ug.mL-1	PMID[20071056]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	=	4.0	ug.mL-1	PMID[19805554]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	=	30.0	ug.mL-1	PMID[17118653]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	30.0	ug.mL-1	PMID[23746784]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	64.0	ug.mL-1	PMID[18077425]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_bilirubinemia	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_cholecystitis	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_cholelithiasis	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_cirrhosis	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_hepatic failure	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_hepatic necrosis	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_hepatomegaly	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_jaundice	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_liver fatty	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_liver function tests abnormal	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_Combined Scores	=	0.0	n.a.	PMID[22194678]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	160.0	nM	PMID[14738378]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC90	=	0.14	uM	PMID[12502327]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC50	=	120.0	nM	DOI[10.1039/C4MD00399C]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC90	=	0.12	uM	PMID[20666364]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC50	=	70.0	nM	PMID[25286284]
NPT314	Organism	Bacillus cereus	Bacillus cereus	IZ	=	20.0	mm	PMID[13678413]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC90	=	80.0	nM	PMID[9868159]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	70.0	nM	PMID[2824776]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC90	=	0.08	ug.mL-1	PMID[18177012]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	160.0	nM	PMID[9514009]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	0.07	ug.mL-1	PMID[23999041]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	79.8	%	Open TG-GATES in vivo data: Biochemistry
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	96.0	%	Open TG-GATES in vivo data: Biochemistry
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	97.3	%	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	98.0	%	Open TG-GATES in vivo data: Biochemistry
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC90	=	0.08	uM	PMID[25763602]
NPT314	Organism	Bacillus cereus	Bacillus cereus	IZ	=	32.0	mm	PMID[20061160]
NPT3147	Organism	Kocuria rhizophila	Kocuria rhizophila	MIC	=	3420.0	nM	PMID[25137549]
NPT314	Organism	Bacillus cereus	Bacillus cereus	MIC	=	9.4	ug.mL-1	PMID[8277308]
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	<=	0.25	ug.mL-1	DOI[10.6019/CHEMBL1201861]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	102.0	nM	PMID[23398362]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC90	=	141.0	nM	PMID[25798528]
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	200.0	nM	PMID[19674906]
NPT3608	Organism	Salmonella enteritidis	Salmonella enterica subsp. enterica serovar Enteritidis	MIC	=	14000.0	nM	PMID[19199792]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	1700.0	nM	PMID[28287735]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	50000.0	nM	PMID[28287735]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	27000.0	nM	PMID[28287735]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	3400.0	nM	PMID[28287735]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	27000.0	nM	PMID[28287735]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	<	0.25	ug.mL-1	PMID[30282323]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	=	128.0	ug.mL-1	PMID[17502402]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC>95	=	0.0625	uM	PMID[30742437]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MBC>99.9	=	0.125	uM	PMID[30742437]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC90	=	14630.0	nM	PMID[32950907]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	256.0	ug.mL-1	PMID[37122541]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	2500.0	nM	PMID[38124427]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Inhibition	=	100.0	%	PMID[36877255]
NPT30028	Organism	Mycobacterium parascrofulaceum	Mycobacterium parascrofulaceum	MIC	=	250.0	nM	PMID[36037791]
NPT29356	Organism	Klebsiella aerogenes	Klebsiella aerogenes	MIC	>	512.0	ug.mL-1	PMID[37122541]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_liver disease	=	0.0	n.a.	PMID[22194678]

In vivo activity

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	81.2	%	PMID[27690420]
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	92.0	%	PMID[27690420]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_elevated liver function tests	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_hepatitis	=	0.0	n.a.	PMID[22194678]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	25.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	36400.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	233.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	81.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	144.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	105.6	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	692.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	303.2	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	5.6	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1254.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	105.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	22.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	114.8	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.52	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	147.0	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	61000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	10.6	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.032	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.11	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	6.63	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.14	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	1.17	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.38	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	1.28	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7450000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	45.74	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	147200.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	8110.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	81.3	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	19.76	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	321600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	61.38	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.76	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	14.9	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1322400.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	31.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	36600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	228.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	79.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	112.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	107.0	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	570.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	233.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	5.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1244.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	106.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	24.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	105.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.34	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	149.2	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	64800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	9.4	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.13	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.14	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	13.53	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.4	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	2.33	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.72	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.86	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7740000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	45.98	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	138600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	16610.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	81.34	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	18.0	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	302200.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	59.4	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	2.46	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	14.14	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1445500.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	30.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	37100.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	186.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	78.2	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	142.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	105.4	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	449.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	334.3	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	6.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1472.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	123.1	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	9.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	100.1	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.57	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	149.5	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.1	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	66600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	12.6	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.091	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	9.91	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.21	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	1.56	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.77	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.92	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	8210000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	47.53	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	156500.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	11910.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	83.34	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	19.07	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	329300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	57.9	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.68	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	12.97	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1323800.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	28.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	35600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	209.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	80.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	146.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	107.2	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	624.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	231.2	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1366.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	109.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	23.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	117.4	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.46	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	11.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.042	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.076	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	7.26	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.13	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	0.83	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.52	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7720000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	47.66	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	154600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	8360.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	86.2	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	20.02	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	324400.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	61.7	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.62	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	10.4	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1365600.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	30.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	34400.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	190.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	130.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	107.8	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	708.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	151.2	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1198.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	78.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	32.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	99.4	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.62	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	150.6	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	61800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	6.6	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.12	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.12	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	10.45	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.29	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	1.84	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.88	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.88	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7680000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	45.32	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	148800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	12880.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	80.34	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	19.4	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	328800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	59.02	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	2.26	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	15.14	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1513400.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	29.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	36000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	128.89	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	84.7	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	177.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	621.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	292.2	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	6.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1362.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	129.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	17.1	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	100.4	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.81	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	152.5	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.6	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	14.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.097	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.087	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	9.1	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.18	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	1.34	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.84	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7950000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	44.83	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	10860.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	83.57	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	18.72	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	332400.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	56.35	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.64	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	12.66	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1439300.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	51.67	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	39700.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	351.17	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	82.33	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	151.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	34500000.0	nM	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	100.0	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	803.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	316.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	1.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1491.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	105.67	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	9.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	108.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.47	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	144.2	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	58300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	8.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	7637.67	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	67.83	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	661.17	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.0	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.0	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5380000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	33.67	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	128800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	8370.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	91.17	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	23.95	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	382300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	62.6	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	0.83	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	8.0	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBCNUC	=	0.17	/100WBC	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	865000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	52.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	364.83	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	82.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	170.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	32330000.0	nM	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	758.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	419.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	2.1	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1550.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	111.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	11.33	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	103.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	1.8	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	59800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	6.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	6333.5	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	38.83	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	661.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5440000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	34.17	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	132200.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	7030.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	90.17	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	24.38	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	387000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	62.95	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	0.5	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	9.33	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBCNUC	=	0.0	/100WBC	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	924330.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	99.6	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.37	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	144.64	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	53.67	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	41300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	308.67	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	140.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	35670000.0	nM	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	99.0	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	773.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	320.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1456.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	98.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	9.33	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	111.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.07	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	144.47	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	60300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	9.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	8480.67	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	225.67	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	993.67	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5640000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	34.43	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	130000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	9700.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	88.0	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	23.03	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	377700.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	61.0	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	2.33	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	9.67	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBCNUC	=	0.33	/100WBC	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	903330.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	72.67	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	36300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	187.33	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	329.33	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	160.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	32670000.0	nM	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	98.67	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	813.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	388.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	1.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1626.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	112.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	9.67	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	102.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.93	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	142.37	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	1.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	53000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	5.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	3175.67	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	11.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	480.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5480000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	33.0	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	126300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	3670.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	86.67	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	23.0	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	383000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	60.1	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	0.33	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	13.0	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	622330.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	50.67	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	41700.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	370.33	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	84.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	143.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	35000000.0	nM	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	743.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	385.33	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	1.8	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1783.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	142.67	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	9.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	112.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.0	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	143.33	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	59700.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	7.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	29.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	10165.67	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	121.67	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	950.33	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.33	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5810000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	35.97	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	137000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	11270.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	90.0	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	23.6	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	381000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	61.93	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.0	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	8.67	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1125330.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	59.67	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	39000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	382.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	82.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	173.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	636.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	235.67	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	1.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1606.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	113.33	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	107.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.04	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	143.97	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	1.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	5.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	6237.33	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	19.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	743.67	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5270000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	33.87	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	131300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	7000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	89.33	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	24.93	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	388000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	64.2	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	10.33	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1177670.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]

Experimental ADME

Experiment Model	Experiment Tissue	ADME Type	ADME Relation	ADME Value	ADME Unit	Reference
Homo sapiens	n.a.	Fu	=	0.88	n.a.	PMID[18426954]

Experimental Toxicity

Quantitative toxicity

Experiment Model	Experiment Organism	Toxicity Type	Toxicity Relation	Toxicity Value	Toxicity Unit	Reference
-	Mus musculus	LD50	=	300.0	mg.kg-1	PMID[28343755]

Common Abbreviations:
LC: Lethal Concentration; LD: Lethal Dose; LT:Lethal Time; NOAEL: No-observed-adverse-effect Level; BMDL: Benchmark Dose Lower Confidence Limit; BMD: Benchmark Dose; BMC:Benchmark Concentration; LOAEL: Lowest Observed Adverse Effect Level; RfD:Reference Dose; RfC:Reference Concentration; MRL: Minimal Risk Level; MEG: Maximum Exposure Guideline; PAC: Protective Action Criteria

Categorical toxicity labels

Hepatotoxicity	Carcinogenicity	Mutagenicity	Cardiotoxicity	Respiratory Toxicity	Eye Irritation	Endocrine Disruption

Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP toxicity records from domain-specific databases. These databases include:
☉ ToxValDB: a curated database that compiles quantitative toxicity values for chemicals from diverse public sources to support toxicological research and risk assessment.
☉ TOXRIC: a comprehensive, free-to-access, online database providing toxicological/feature data. The toxicity labels are retrieved from this database. [PMID: 36400569]

Chemically structural similarity

Similar Active Natural Products in NPASS

Top-200 similar NPs were calculated against the active-NP-set (includes approximately 50,000 NPs with experimentally-derived bioactivity available in NPASS)

Similarity is measured using the Tanimoto coefficient (Tc) , which compares the binary fingerprints of two molecules. Tc is calculated as the intersection divided by the union of '1' bits in the fingerprints, ranging from 0 to 1, with 1 indicating highest similarity.

● The left chart: Distribution of similarity level between NPC330590 and all remaining natural products in the NPASS database.
● The right table: Most similar natural products (Tc>=0.5 or Top200).

range	Tanimoto Coefficient
0-0.1	37565
0.1-0.2	11493
0.2-0.3	786
0.3-0.4	8
0.4-0.5	3
0.5-0.6	1
0.6-0.7	2
0.7-0.8	1
0.8-0.85	0
0.85-0.9	0
0.9-0.95	0
0.95-1	0

Similarity Score	Similarity Level	Natural Product ID
0.6176	Remote Similarity	NPC43850
0.6176	Remote Similarity	NPC485811
0.5972	Remote Similarity	NPC477060

Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

● The left chart: Distribution of similarity level between NPC330590 and all drugs/candidates.
● The right table: Most similar clinical/approved drugs (Tc>=0.5 or Top200).

range	Tanimoto Coefficient
0-0.1	7274
0.1-0.2	1799
0.2-0.3	65
0.3-0.4	1
0.4-0.5	5
0.5-0.6	2
0.6-0.7	1
0.7-0.8	1
0.8-0.85	0
0.85-0.9	0
0.9-0.95	1
0.95-1	1

Similarity Score	Similarity Level	Drug ID	Developmental Stage
1.0	High Similarity	NPD5378	Phase 4
0.9412	High Similarity	NPD5377	Approved
0.7397	Intermediate Similarity	NPD5381	Phase 2
0.6176	Remote Similarity	NPD3203	Phase 4
0.5972	Remote Similarity	NPD3201	Approved
0.5714	Remote Similarity	NPD5376	Approved

Bioactivity similarity

Similar Natural Products in NPASS

Similarity level is defined by Bioactivity similarity was calculated based on bioactivity descriptors of compounds. The bioactivity descriptors were calculated by a recently developed AI algorithm Chemical Checker (CC) [Nature Biotechnology, 38:1087–1096, 2020; Nature Communications, 12:3932, 2021], which evaluated bioactivity similarities at five levels:
☉ A: chemistry similarity;
☉ B: biological targets similarity;
☉ C: networks similarity;
☉ D: cell-based bioactivity similarity;
☉ E: similarity based on clinical data.
Those 5 categories of CC bioactivity descriptors were calculated and then subjected to manifold projection using UMAP algorithm, to project all NPs on a 2-Dimensional space. The current NP was highlighted with a small circle in the 2-D map. Below figures: left-to-right, A-to-E.

A: chemistry similarity

B: biological targets similarity

C: networks similarity

D: cell-based bioactivity similarity

E: similarity based on clinical data