Natural Product Target: Thioredoxin glutathione reductase

Target ID:   NPT3
Target Name:   Thioredoxin glutathione reductase
Target Type:   Individual Protein
Organism of Target:   Schistosoma mansoni
Target External ID:   Uniprot_ID:[ Q962Y6]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC43945 Menadione 2
NPC4665 3,4-Dihydroxyphenylacetic Acid 1
NPC204932 Catechol 1
NPC41263 2-(2-Acetyl-3,5-Dihydroxyphenyl)Acetic Acid 1
NPC97577 Lovastatin 1
NPC260491 (2R,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-Trihydroxy-2,3-Dihydrochromen-4-One 1
NPC55304 Brefeldin A 1
NPC61 Rosmarinic Acid 1
NPC288411 Magnolol 1
NPC160972 Protoapigenone 1
NPC311660 Questiomycin B 1
NPC5413 Gamolenic Acid 1
NPC205034 4-[(E)-2-[(1R,4As,5R,6R,8Ar)-6-Hydroxy-5-(Hydroxymethyl)-5,8A-Dimethyl-2-Methylidene-3,4,4A,6,7,8-Hexahydro-1H-Naphthalen-1-Yl]Ethenyl]-2H-Furan-5-One 1
NPC328682 3,6-Bis(3,4,5-Trimethoxyphenyl)-1,3,3A,4,6,6A-Hexahydrofuro[3,4-C]Furan 1
NPC100887 Eupafolin 1
NPC263265 Obacunone 1
NPC189314 Mercaptopurine 1
NPC132804 3,6,7-Trimethoxyphenanthrene-2,5-Diol 1
NPC289004 n.a. 1
NPC161957 Aromaticin 1
NPC312870 n.a. 1
NPC68441 Gossypol 1
NPC206819 Agroclavine 1
NPC328729 Diethanolamine 1
NPC102423 Indole-3-Carbinol 1
NPC31171 Cytochalasin B 1
NPC182646 Sid22411775 1
NPC136330 Piperine 1
NPC290550 Emodic Acid 1
NPC162939 6-[(3E,5E,7S)-5,7-Dimethyl-2-Oxonona-3,5-Dienyl]-2,4-Dihydroxy-3-Methylbenzaldehyde 1
NPC313985 Methyl 18-Hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-Dodecahydroyohimban-19-Carboxylate 1
NPC69057 (E)-1,4-Bis(4-Methylphenyl)But-2-Ene-1,4-Dione 1
NPC208022 2-Aminophenoxazin-3-One 1
NPC328740 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-6-[3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Chromen-4-One 1
NPC102843 [(1S,3R)-3-Hydroxy-4-[(3E,5E,7E,9E,11E,13E,15E)-18-[(1R,3S,6S)-3-Hydroxy-1,5,5-Trimethyl-7-Oxabicyclo[4.1.0]Heptan-6-Yl]-3,7,12,16-Tetramethyl-17-Oxooctadeca-1,3,5,7,9,11,13,15-Octaenylidene]-3,5,5-Trimethylcyclohexyl] Acetate 1
NPC269023 Capillarin 1
NPC476440 Tpck 1
NPC138978 Altenusin 1
NPC294548 Linolenic Acid 1
NPC168829 Honokiol 1
NPC314372 N-[2-(1H-Indol-3-Yl)Ethyl]Propanamide 1
NPC71664 Chalcone 1
NPC215507 n.a. 1
NPC329161 Slazinic Acid 1
NPC106334 Asterric Acid 1
NPC275305 [(6Ar,9R)-7-Methyl-6,6A,8,9-Tetrahydro-4H-Indolo[4,3-Fg]Quinoline-9-Yl]Methanol 1
NPC192674 9-Aminocamptothecin 1
NPC140840 Sulfuretin 1
NPC294902 Caffeic Acid 1
NPC169749 Myricetin 1
NPC316052 Erbstatin 1
NPC73511 Prunetrin 1
NPC216318 5,6,7,8-Tetrahydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 1
NPC329203 5-Hydroxy-2-(4-Hydroxyphenyl)-7-Methoxy-2,3-Dihydrochromen-4-One 1
NPC106791 n.a. 1
NPC275960 Helenalin 1
NPC36 (3S)-3,5,7-Trihydroxy-2-[(2S,3S)-3-(4-Hydroxy-3-Methoxyphenyl)-2-(Hydroxymethyl)-2,3-Dihydro-1,4-Benzodioxin-6-Yl]-2,3-Dihydrochromen-4-One 1
NPC143402 Erythrosine 1
NPC295204 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] (E)-2-Methylbut-2-Enoate 1
NPC170018 (9R)-9-[(9R)-2-Carboxy-4-Hydroxy-10-Oxo-5-[(3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-9H-Anthracen-9-Yl]-4-Hydroxy-10-Oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-9H-Anthracene-2-Carboxylic Acid 1
NPC317177 Tretinoin 1
NPC76682 n.a. 1
NPC224764 Potassium;1H-Indol-3-Yl Sulfate 1
NPC476120 Desmosdumotin C 1
NPC108434 (1S)-1-[[4-[2-Hydroxy-5-[[(1S)-7-Hydroxy-6-Methoxy-1,2,3,4-Tetrahydroisoquinolin-1-Yl]Methyl]Phenoxy]Phenyl]Methyl]-6-Methoxy-1,2,3,4-Tetrahydroisoquinolin-7-Ol 1
NPC276014 Cyclovalone 1
NPC55772 3-(1H-Indol-3-Yl)-2-Oxopropanoic Acid 1
NPC145885 3-(1H-Indol-3-Yl)-2-(Trimethylazaniumyl)Propanoate 1
NPC295531 Oxytetracycline 1
NPC173555 Digoxin 1
NPC317237 Haematoxylin 1
NPC319933 2,4-Dibromo-1-(2,4-Dibromophenoxy)Benzene 1
NPC77000 Cryptotanshinone 1
NPC226699 Paroxypropione 1
NPC469978 Sid14737105 1
NPC109083 Curcumin 1
NPC276047 Harpagoside 1
NPC56109 Ergocristine 1
NPC146976 (6,7-Dimethoxyisoquinolin-1-Yl)-(3,4-Dimethoxyphenyl)Methanone 1
NPC34864 Piceatannol 1
NPC19694 (2R)-2-[(1E,3E)-Penta-1,3-Dienyl]-2,3-Dihydro-1-Benzofuran-5,7-Diol 1
NPC176740 Rutin 1
NPC321011 2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-2,3-Dihydrochromen-4-One 1
NPC7839 n.a. 1
NPC227396 Prostaglandin B1 1
NPC110764 Hydroxytyrosol 1
NPC280312 3,3-Dibromoprop-2-Enoic Acid 1
NPC63598 Sorbic Acid 1
NPC149300 Tannic Acid 1
NPC298486 2-(3,4-Dimethoxyphenyl)-N-Methylethanamine 1
NPC179950 Isoquercetin 1
NPC321402 (8R,9S,13S,14S,17S)-13-Methyl-6,7,8,9,11,12,14,15,16,17-Decahydrocyclopenta[A]Phenanthrene-2,3,17-Triol 1
NPC87231 Cardamomin 1
NPC228978 Vitamin A Palmitate 1
NPC44270 2,4-Dibromo-6-(2,4-Dibromophenoxy)Phenol 1
NPC1682 2-Methyl-3-[(E)-3,7,11,15-Tetramethylhexadec-2-Enyl]Naphthalene-1,4-Dione 1
NPC280339 Isothymonin 1
NPC67076 Prostaglandin A2 1
NPC152778 4-[(E)-2-[(1R,5R,6R,8Ar)-6-Hydroxy-5-(Hydroxymethyl)-5,8A-Dimethyl-2-Methylidene-3,4,4A,6,7,8-Hexahydro-1H-Naphthalen-1-Yl]Ethenyl]-2H-Furan-5-One 1
NPC300984 Lobaric Acid 1
NPC181594 Kamebanin 1
NPC321561 Methyldopa 1
NPC91495 Arachidonic Acid 1
NPC25581 3-(3,4-Dihydroxyphenyl)-2-[(E)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoyl]Oxypropanoic Acid 1
NPC470091 Stictic Acid 1
NPC114682 3-Hydroxy-1-(4-Hydroxyphenyl)Propan-1-One 1
NPC281398 Tanshinone Iia 1
NPC154962 n.a. 1
NPC301702 Aminosalicylic Acid 1
NPC189436 Thiamine Hydrochloride 1
NPC322598 3-Phenyl-2-(Trimethylazaniumyl)Propanoate 1
NPC92722 (E)-1-(2,3-Dihydroxy-4,6-Dimethoxyphenyl)-3-Phenylprop-2-En-1-One 1
NPC235077 Triamcinolone 1
NPC193948 Terretonin 1
NPC118844 n.a. 1
NPC282294 Ethacrynic Acid 1
NPC155444 Ergocryptine 1
NPC302188 Gabapentin 1
NPC199023 Nelumol A 1
NPC324772 Calcitriol 1
NPC93241 Tanshinone I 1
NPC239954 n.a. 1
NPC46565 Hinokitiol 1
NPC120719 4-Tert-Butylbenzene-1,2-Diol 1
NPC284475 Menatetrenone 1
NPC155963 [(1R,2R)-2,3-Dihydroxy-1-(7-Methoxy-2-Oxochromen-6-Yl)-3-Methylbutyl] (E)-2-Methylbut-2-Enoate 1
NPC304079 (2E)-3,7-Dimethylocta-2,6-Dienoic Acid 1
NPC201658 Coronopilin 1
NPC325871 1,2,9,10-Tetramethoxy-6-Methyl-5,6,6A,7-Tetrahydro-4H-Dibenzo[De,G]Quinoline 1
NPC93739 Physodic Acid 1
NPC246162 (+)-Taxifolin 1
NPC475073 Penicillic Acid 1
NPC120798 n.a. 1
NPC286342 3-O-Methylquercetin 1
NPC158179 Icosa-5,8,11,14-Tetraynoic Acid 1
NPC304836 2-Nitroethanol 1
NPC203468 Tryptophan 1
NPC41178 Tetrahydroberberine 1
NPC9161 Ergocalciferol 1
NPC250436 Epigalocatechin Gallate 1
NPC471785 Sid11111800 1
NPC126029 (-)-Epicatechin 1
NPC287764 n.a. 1
NPC160235 [2-Hydroxy-2-(2-Hydroxy-4-Methylphenyl)-3-(2-Methylpropanoyloxy)Propyl] 2-Methylpropanoate 1
NPC307006 2-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)Acetic Acid 1
NPC204156 Oxyphenbutazone 1
NPC326661 (E,8R)-8-[(2R,3R,5R,6S)-3,5-Dihydroxy-6-Methyloxan-2-Yl]Oxynon-2-Enoic Acid 1
NPC95868 2,3-Diphenylcycloprop-2-En-1-One 1
NPC256838 3-Aminophenol 1
NPC174251 Sid24841469 1
NPC129533 n.a. 1
NPC288240 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] 2-Methylprop-2-Enoate 1
NPC160900 (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 1
NPC309757 Grossheimin 1

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