Drug Information

Drug ID:  NPD5898
Drug Name:  Fluvastatin
Molecular Formula:  C24H26FNO4
Canonical SMILES:  OC(=O)CC(CC(/C=C/c1c(c2ccc(cc2)F)c2c(n1C(C)C)cccc2)O)O
Standard InCHI:  InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+
Standard InCHIKey:  FJLGEFLZQAZZCD-VAWYXSNFSA-N
Max Developmental Stage:  Approved
Max Developmental Stage Source:  ChEMBL

  Structural Similarity Between NPASS Natural Products and NPD5898

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.


  Similar Natural Products

High Similarity Level: Tc>=0.85; Intermediate Similarity Level: 0.7 <= Tc < 0.85; Remote Similarity Level: 0.65 <= Tc < 0.7

Similarity Level Similarity Score Natural Product ID
High Similarity 0.882 NPC102008
Intermediate Similarity 0.8011 NPC472323
Intermediate Similarity 0.7877 NPC15840
Intermediate Similarity 0.7853 NPC469938
Intermediate Similarity 0.7772 NPC175474
Intermediate Similarity 0.7765 NPC326575
Intermediate Similarity 0.7747 NPC470003
Intermediate Similarity 0.7735 NPC113626
Intermediate Similarity 0.7656 NPC476874
Intermediate Similarity 0.7644 NPC79129
Intermediate Similarity 0.7644 NPC81654
Intermediate Similarity 0.7644 NPC249150
Intermediate Similarity 0.7644 NPC195461
Intermediate Similarity 0.7644 NPC49196
Intermediate Similarity 0.7644 NPC313985
Intermediate Similarity 0.7632 NPC50503
Intermediate Similarity 0.7611 NPC472122
Intermediate Similarity 0.7611 NPC24594
Intermediate Similarity 0.7609 NPC79062
Intermediate Similarity 0.7609 NPC472107
Intermediate Similarity 0.7539 NPC149708
Intermediate Similarity 0.7527 NPC213468
Intermediate Similarity 0.7514 NPC470507
Intermediate Similarity 0.75 NPC472097
Intermediate Similarity 0.75 NPC472104
Intermediate Similarity 0.7486 NPC187827
Intermediate Similarity 0.7486 NPC472105
Intermediate Similarity 0.7474 NPC181502
Intermediate Similarity 0.7474 NPC85066
Intermediate Similarity 0.7473 NPC234987
Intermediate Similarity 0.7459 NPC472119
Intermediate Similarity 0.7448 NPC52557
Intermediate Similarity 0.7446 NPC71037
Intermediate Similarity 0.7444 NPC158129
Intermediate Similarity 0.7436 NPC476115
Intermediate Similarity 0.7419 NPC62510
Intermediate Similarity 0.7407 NPC129909
Intermediate Similarity 0.7405 NPC472109
Intermediate Similarity 0.7405 NPC143533
Intermediate Similarity 0.7405 NPC472110
Intermediate Similarity 0.7404 NPC33949
Intermediate Similarity 0.7403 NPC34508
Intermediate Similarity 0.738 NPC478077
Intermediate Similarity 0.738 NPC235684
Intermediate Similarity 0.7371 NPC312870
Intermediate Similarity 0.7371 NPC199851
Intermediate Similarity 0.7371 NPC128265
Intermediate Similarity 0.7371 NPC254240
Intermediate Similarity 0.7371 NPC294909
Intermediate Similarity 0.7368 NPC55493
Intermediate Similarity 0.7366 NPC258480
Intermediate Similarity 0.736 NPC18661
Intermediate Similarity 0.736 NPC238457
Intermediate Similarity 0.736 NPC40779
Intermediate Similarity 0.7348 NPC6982
Intermediate Similarity 0.7347 NPC98715
Intermediate Similarity 0.7344 NPC245916
Intermediate Similarity 0.7337 NPC270009
Intermediate Similarity 0.7337 NPC133261
Intermediate Similarity 0.7337 NPC478158
Intermediate Similarity 0.7333 NPC300183
Intermediate Similarity 0.7333 NPC78020
Intermediate Similarity 0.7323 NPC225821
Intermediate Similarity 0.7323 NPC46225
Intermediate Similarity 0.7323 NPC474905
Intermediate Similarity 0.7322 NPC267885
Intermediate Similarity 0.732 NPC241024
Intermediate Similarity 0.7312 NPC159125
Intermediate Similarity 0.7304 NPC281049
Intermediate Similarity 0.7302 NPC321708
Intermediate Similarity 0.7297 NPC24864
Intermediate Similarity 0.7292 NPC289299
Intermediate Similarity 0.7292 NPC57994
Intermediate Similarity 0.7287 NPC315555
Intermediate Similarity 0.7287 NPC66210
Intermediate Similarity 0.7286 NPC258062
Intermediate Similarity 0.7286 NPC127677
Intermediate Similarity 0.7283 NPC37548
Intermediate Similarity 0.7283 NPC14325
Intermediate Similarity 0.7283 NPC28848
Intermediate Similarity 0.7268 NPC189812
Intermediate Similarity 0.7268 NPC203468
Intermediate Similarity 0.7268 NPC149155
Intermediate Similarity 0.7268 NPC329688
Intermediate Similarity 0.7268 NPC110500
Intermediate Similarity 0.7268 NPC474916
Intermediate Similarity 0.7263 NPC311276
Intermediate Similarity 0.7263 NPC206967
Intermediate Similarity 0.7253 NPC126492
Intermediate Similarity 0.725 NPC477548
Intermediate Similarity 0.7243 NPC472443
Intermediate Similarity 0.7243 NPC248462
Intermediate Similarity 0.7243 NPC248041
Intermediate Similarity 0.7243 NPC219336
Intermediate Similarity 0.7243 NPC283219
Intermediate Similarity 0.7243 NPC126709
Intermediate Similarity 0.7232 NPC469762
Intermediate Similarity 0.7225 NPC473763
Intermediate Similarity 0.7225 NPC117244
Intermediate Similarity 0.7219 NPC472108
Intermediate Similarity 0.7219 NPC139291
Intermediate Similarity 0.7219 NPC104483
Intermediate Similarity 0.7211 NPC63199
Intermediate Similarity 0.7211 NPC102338
Intermediate Similarity 0.7211 NPC111602
Intermediate Similarity 0.7211 NPC61435
Intermediate Similarity 0.7211 NPC196251
Intermediate Similarity 0.7208 NPC193761
Intermediate Similarity 0.7206 NPC476114
Intermediate Similarity 0.7196 NPC94752
Intermediate Similarity 0.7196 NPC311858
Intermediate Similarity 0.7192 NPC229348
Intermediate Similarity 0.7189 NPC293472
Intermediate Similarity 0.7189 NPC64436
Intermediate Similarity 0.7189 NPC14113
Intermediate Similarity 0.7189 NPC15573
Intermediate Similarity 0.7189 NPC217372
Intermediate Similarity 0.7189 NPC145885
Intermediate Similarity 0.7189 NPC183662
Intermediate Similarity 0.7189 NPC84827
Intermediate Similarity 0.7184 NPC187951
Intermediate Similarity 0.7184 NPC52254
Intermediate Similarity 0.7177 NPC141428
Intermediate Similarity 0.7175 NPC469785
Intermediate Similarity 0.7166 NPC192270
Intermediate Similarity 0.7164 NPC162860
Intermediate Similarity 0.7164 NPC271862
Intermediate Similarity 0.7159 NPC200743
Intermediate Similarity 0.7158 NPC470498
Intermediate Similarity 0.7157 NPC478157
Intermediate Similarity 0.7157 NPC313640
Intermediate Similarity 0.7151 NPC81229
Intermediate Similarity 0.7151 NPC255229
Intermediate Similarity 0.7151 NPC55772
Intermediate Similarity 0.715 NPC53344
Intermediate Similarity 0.715 NPC323927
Intermediate Similarity 0.7143 NPC87856
Intermediate Similarity 0.7143 NPC151976
Intermediate Similarity 0.7143 NPC201700
Intermediate Similarity 0.7143 NPC207020
Intermediate Similarity 0.7143 NPC75634
Intermediate Similarity 0.7143 NPC192674
Intermediate Similarity 0.7143 NPC280290
Intermediate Similarity 0.7136 NPC82070
Intermediate Similarity 0.7136 NPC314648
Intermediate Similarity 0.7135 NPC134586
Intermediate Similarity 0.7135 NPC150048
Intermediate Similarity 0.7135 NPC121903
Intermediate Similarity 0.7135 NPC203754
Intermediate Similarity 0.7135 NPC129721
Intermediate Similarity 0.7129 NPC234999
Intermediate Similarity 0.7128 NPC472444
Intermediate Similarity 0.7128 NPC469358
Intermediate Similarity 0.7122 NPC204491
Intermediate Similarity 0.7122 NPC203614
Intermediate Similarity 0.7119 NPC38736
Intermediate Similarity 0.7115 NPC2395
Intermediate Similarity 0.7113 NPC19692
Intermediate Similarity 0.7113 NPC220151
Intermediate Similarity 0.7112 NPC469896
Intermediate Similarity 0.7112 NPC91179
Intermediate Similarity 0.7111 NPC194881
Intermediate Similarity 0.7109 NPC57690
Intermediate Similarity 0.7108 NPC221100
Intermediate Similarity 0.7108 NPC234078
Intermediate Similarity 0.7108 NPC267965
Intermediate Similarity 0.7105 NPC99428
Intermediate Similarity 0.7098 NPC472292
Intermediate Similarity 0.7097 NPC111275
Intermediate Similarity 0.7097 NPC211997
Intermediate Similarity 0.7097 NPC151939
Intermediate Similarity 0.7095 NPC235885
Intermediate Similarity 0.709 NPC228835
Intermediate Similarity 0.7088 NPC54988
Intermediate Similarity 0.7083 NPC329858
Intermediate Similarity 0.7079 NPC469743
Intermediate Similarity 0.7079 NPC285469
Intermediate Similarity 0.7077 NPC472293
Intermediate Similarity 0.7077 NPC472116
Intermediate Similarity 0.7072 NPC21174
Intermediate Similarity 0.7072 NPC271797
Intermediate Similarity 0.7072 NPC102423
Intermediate Similarity 0.7072 NPC476118
Intermediate Similarity 0.7071 NPC475506
Intermediate Similarity 0.7065 NPC54420
Intermediate Similarity 0.7062 NPC25008
Intermediate Similarity 0.7062 NPC73952
Intermediate Similarity 0.7062 NPC247735
Intermediate Similarity 0.7062 NPC469760
Intermediate Similarity 0.7062 NPC472210
Intermediate Similarity 0.7062 NPC259644
Intermediate Similarity 0.7062 NPC81802
Intermediate Similarity 0.7062 NPC469765
Intermediate Similarity 0.7062 NPC269886
Intermediate Similarity 0.7062 NPC472295
Intermediate Similarity 0.7062 NPC469763
Intermediate Similarity 0.7062 NPC469786
Intermediate Similarity 0.7059 NPC215795
Intermediate Similarity 0.7059 NPC176199
Intermediate Similarity 0.7056 NPC472296

Drug Structure

External Identifiers

TTD  
DrugBank  
ChEMBL  
IUPHAR/BPS  
PharmaGKB  
KEGG Drug  
PubChem CID  
ChEBI  
CAS Number  

Drug Properties

Molecular Weight  411.18
ALogP  -0.5015
MLogP  3.44
XLogP  4.958
HDA  5
HBD  3
Rotatable Bonds  14
TPSA  82.69
RO5 Violation  0