Natural Product ID:   | NPC176199 |
Common Name:   | Elymoclavine |
IUPAC Name:   | [(6aR,10aR)-7-methyl-6,6a,8,10a-tetrahydro-4H-indolo[4,3-fg]quinoline-9-yl]methanol |
Synonyms:   | |
Molecular Formula:   | C16H18N2O |
Standard InCHIKey:   | DAVNRFCJMIONPO-UKRRQHHQSA-N |
Standard InCHI:   | InChI=1S/C16H18N2O/c1-18-8-10(9-19)5-13-12-3-2-4-14-16(12)11(7-17-14)6-15(13)18/h2-5,7,13,15,17,19H,6,8-9H2,1H3/t13-,15-/m1/s1 |
Canonical SMILES:   | OCC1=C[C@H]2[C@H](N(C1)C)Cc1c3c2cccc3[nH]c1 |
First Find Year:   | |
Max Developmental Stage:   | |
Synthetic Gene Cluster:   | BGC0001267 ; |
Organism ID | Organism Name | Taxonomy Level | Family | SuperKingdom | Isolation Part | Collection Location | Collection Time | Reference |
---|---|---|---|---|---|---|---|---|
NPO24009 | Claviceps purpurea | Species | Clavicipitaceae | Eukaryota | TCM_Taiwan* |
Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT2 | Others | Unspecified | Activity | = | 70 | % | 10.1021/np50009a003 | |
NPT4975 | Organism | Claviceps | Claviceps | FC | = | 2 | 10.1021/np50009a003 | |
NPT4975 | Organism | Claviceps | Claviceps | Activity | = | 50 | % | 10.1021/np50009a003 |
NPT29 | Organism | Rattus norvegicus | Rattus norvegicus | Inhibition | = | 71 | % | 423180 |
NPT29 | Organism | Rattus norvegicus | Rattus norvegicus | Inhibition | = | 71 | % | 915908 |
NPT29 | Organism | Rattus norvegicus | Rattus norvegicus | Inhibition | = | 75 | % | 915908 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC176199 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
1.0 | High Similarity | NPC215795 |
0.9688 | High Similarity | NPC37423 |
0.9688 | High Similarity | NPC275305 |
0.9568 | High Similarity | NPC68354 |
0.95 | High Similarity | NPC194411 |
0.9182 | High Similarity | NPC318065 |
0.9182 | High Similarity | NPC206819 |
0.8944 | High Similarity | NPC56765 |
0.8902 | High Similarity | NPC95783 |
0.8712 | High Similarity | NPC41257 |
0.8704 | High Similarity | NPC51054 |
0.8688 | High Similarity | NPC105818 |
0.8688 | High Similarity | NPC24678 |
0.865 | High Similarity | NPC286427 |
0.8623 | High Similarity | NPC201700 |
0.858 | High Similarity | NPC313791 |
0.8553 | High Similarity | NPC159856 |
0.8553 | High Similarity | NPC314372 |
0.8538 | High Similarity | NPC151939 |
0.8521 | High Similarity | NPC470498 |
0.8485 | Intermediate Similarity | NPC92796 |
0.8485 | Intermediate Similarity | NPC135141 |
0.8476 | Intermediate Similarity | NPC469785 |
0.8452 | Intermediate Similarity | NPC474561 |
0.8452 | Intermediate Similarity | NPC49954 |
0.8443 | Intermediate Similarity | NPC90723 |
0.8439 | Intermediate Similarity | NPC300688 |
0.8428 | Intermediate Similarity | NPC190296 |
0.8424 | Intermediate Similarity | NPC469762 |
0.8415 | Intermediate Similarity | NPC470507 |
0.8402 | Intermediate Similarity | NPC63751 |
0.8354 | Intermediate Similarity | NPC469763 |
0.8354 | Intermediate Similarity | NPC25008 |
0.8354 | Intermediate Similarity | NPC259644 |
0.8354 | Intermediate Similarity | NPC73952 |
0.8354 | Intermediate Similarity | NPC469760 |
0.8354 | Intermediate Similarity | NPC469765 |
0.8354 | Intermediate Similarity | NPC469786 |
0.8344 | Intermediate Similarity | NPC33421 |
0.8343 | Intermediate Similarity | NPC54988 |
0.8343 | Intermediate Similarity | NPC19679 |
0.8333 | Intermediate Similarity | NPC102423 |
0.8333 | Intermediate Similarity | NPC472587 |
0.8323 | Intermediate Similarity | NPC44773 |
0.8323 | Intermediate Similarity | NPC215584 |
0.8303 | Intermediate Similarity | NPC211572 |
0.8303 | Intermediate Similarity | NPC80597 |
0.8303 | Intermediate Similarity | NPC212376 |
0.8303 | Intermediate Similarity | NPC70922 |
0.8303 | Intermediate Similarity | NPC75540 |
0.8303 | Intermediate Similarity | NPC38736 |
0.8282 | Intermediate Similarity | NPC37548 |
0.8274 | Intermediate Similarity | NPC282231 |
0.8253 | Intermediate Similarity | NPC184476 |
0.8239 | Intermediate Similarity | NPC73767 |
0.8225 | Intermediate Similarity | NPC311276 |
0.8225 | Intermediate Similarity | NPC194640 |
0.8225 | Intermediate Similarity | NPC40779 |
0.8214 | Intermediate Similarity | NPC131718 |
0.8214 | Intermediate Similarity | NPC279918 |
0.8197 | Intermediate Similarity | NPC229332 |
0.8187 | Intermediate Similarity | NPC469779 |
0.8187 | Intermediate Similarity | NPC469780 |
0.8187 | Intermediate Similarity | NPC469783 |
0.8187 | Intermediate Similarity | NPC469761 |
0.8187 | Intermediate Similarity | NPC469784 |
0.8187 | Intermediate Similarity | NPC469768 |
0.8187 | Intermediate Similarity | NPC469767 |
0.8171 | Intermediate Similarity | NPC187951 |
0.8137 | Intermediate Similarity | NPC469766 |
0.8129 | Intermediate Similarity | NPC160105 |
0.8125 | Intermediate Similarity | NPC110126 |
0.8121 | Intermediate Similarity | NPC53947 |
0.8114 | Intermediate Similarity | NPC59269 |
0.8113 | Intermediate Similarity | NPC84911 |
0.811 | Intermediate Similarity | NPC471957 |
0.8103 | Intermediate Similarity | NPC329688 |
0.8103 | Intermediate Similarity | NPC189812 |
0.8079 | Intermediate Similarity | NPC233936 |
0.8061 | Intermediate Similarity | NPC124005 |
0.805 | Intermediate Similarity | NPC96102 |
0.805 | Intermediate Similarity | NPC261195 |
0.805 | Intermediate Similarity | NPC29886 |
0.8047 | Intermediate Similarity | NPC230869 |
0.8046 | Intermediate Similarity | NPC314603 |
0.8046 | Intermediate Similarity | NPC34508 |
0.8037 | Intermediate Similarity | NPC242556 |
0.8034 | Intermediate Similarity | NPC163055 |
0.8023 | Intermediate Similarity | NPC49217 |
0.8021 | Intermediate Similarity | NPC300183 |
0.8 | Intermediate Similarity | NPC105127 |
0.8 | Intermediate Similarity | NPC474707 |
0.7989 | Intermediate Similarity | NPC133366 |
0.7989 | Intermediate Similarity | NPC228835 |
0.7966 | Intermediate Similarity | NPC11126 |
0.7966 | Intermediate Similarity | NPC213468 |
0.7956 | Intermediate Similarity | NPC204565 |
0.7956 | Intermediate Similarity | NPC317030 |
0.7944 | Intermediate Similarity | NPC280290 |
0.7939 | Intermediate Similarity | NPC288838 |
0.7939 | Intermediate Similarity | NPC143872 |
0.7935 | Intermediate Similarity | NPC474177 |
0.7931 | Intermediate Similarity | NPC280548 |
0.7917 | Intermediate Similarity | NPC200214 |
0.7912 | Intermediate Similarity | NPC65215 |
0.7912 | Intermediate Similarity | NPC173028 |
0.791 | Intermediate Similarity | NPC248454 |
0.7895 | Intermediate Similarity | NPC473320 |
0.7886 | Intermediate Similarity | NPC6982 |
0.7882 | Intermediate Similarity | NPC216643 |
0.787 | Intermediate Similarity | NPC471458 |
0.7865 | Intermediate Similarity | NPC270009 |
0.7861 | Intermediate Similarity | NPC265576 |
0.7857 | Intermediate Similarity | NPC470233 |
0.7857 | Intermediate Similarity | NPC216713 |
0.7853 | Intermediate Similarity | NPC279081 |
0.7845 | Intermediate Similarity | NPC15102 |
0.7842 | Intermediate Similarity | NPC98715 |
0.7841 | Intermediate Similarity | NPC472123 |
0.7833 | Intermediate Similarity | NPC48938 |
0.7831 | Intermediate Similarity | NPC129042 |
0.7811 | Intermediate Similarity | NPC325903 |
0.7802 | Intermediate Similarity | NPC94752 |
0.7799 | Intermediate Similarity | NPC82295 |
0.7784 | Intermediate Similarity | NPC47190 |
0.7784 | Intermediate Similarity | NPC477134 |
0.7784 | Intermediate Similarity | NPC21605 |
0.7778 | Intermediate Similarity | NPC192270 |
0.7771 | Intermediate Similarity | NPC317430 |
0.7771 | Intermediate Similarity | NPC154293 |
0.7746 | Intermediate Similarity | NPC16667 |
0.7744 | Intermediate Similarity | NPC230002 |
0.7738 | Intermediate Similarity | NPC321911 |
0.7736 | Intermediate Similarity | NPC22079 |
0.772 | Intermediate Similarity | NPC225821 |
0.772 | Intermediate Similarity | NPC46225 |
0.7719 | Intermediate Similarity | NPC285469 |
0.7701 | Intermediate Similarity | NPC294693 |
0.7697 | Intermediate Similarity | NPC63157 |
0.7697 | Intermediate Similarity | NPC293216 |
0.7697 | Intermediate Similarity | NPC473868 |
0.7692 | Intermediate Similarity | NPC475422 |
0.7688 | Intermediate Similarity | NPC304187 |
0.7688 | Intermediate Similarity | NPC477166 |
0.7683 | Intermediate Similarity | NPC312092 |
0.768 | Intermediate Similarity | NPC127677 |
0.768 | Intermediate Similarity | NPC258062 |
0.768 | Intermediate Similarity | NPC87755 |
0.7679 | Intermediate Similarity | NPC201380 |
0.7679 | Intermediate Similarity | NPC179787 |
0.7679 | Intermediate Similarity | NPC469811 |
0.7669 | Intermediate Similarity | NPC251722 |
0.7669 | Intermediate Similarity | NPC314102 |
0.7665 | Intermediate Similarity | NPC475602 |
0.7663 | Intermediate Similarity | NPC17059 |
0.7657 | Intermediate Similarity | NPC470508 |
0.7654 | Intermediate Similarity | NPC288785 |
0.765 | Intermediate Similarity | NPC476319 |
0.7641 | Intermediate Similarity | NPC271862 |
0.7636 | Intermediate Similarity | NPC59084 |
0.7632 | Intermediate Similarity | NPC32200 |
0.763 | Intermediate Similarity | NPC475990 |
0.763 | Intermediate Similarity | NPC6436 |
0.7624 | Intermediate Similarity | NPC198339 |
0.7624 | Intermediate Similarity | NPC24864 |
0.7622 | Intermediate Similarity | NPC169433 |
0.7619 | Intermediate Similarity | NPC63545 |
0.7616 | Intermediate Similarity | NPC141353 |
0.7611 | Intermediate Similarity | NPC293472 |
0.7611 | Intermediate Similarity | NPC326575 |
0.7609 | Intermediate Similarity | NPC171171 |
0.7607 | Intermediate Similarity | NPC325252 |
0.7606 | Intermediate Similarity | NPC157828 |
0.7606 | Intermediate Similarity | NPC195239 |
0.76 | Intermediate Similarity | NPC271734 |
0.7596 | Intermediate Similarity | NPC165495 |
0.7586 | Intermediate Similarity | NPC122141 |
0.7579 | Intermediate Similarity | NPC473640 |
0.7578 | Intermediate Similarity | NPC256893 |
0.7578 | Intermediate Similarity | NPC475450 |
0.7577 | Intermediate Similarity | NPC475288 |
0.7576 | Intermediate Similarity | NPC88097 |
0.7572 | Intermediate Similarity | NPC299594 |
0.7569 | Intermediate Similarity | NPC472443 |
0.7566 | Intermediate Similarity | NPC11445 |
0.7566 | Intermediate Similarity | NPC205403 |
0.7561 | Intermediate Similarity | NPC150259 |
0.7558 | Intermediate Similarity | NPC207726 |
0.7558 | Intermediate Similarity | NPC34844 |
0.7556 | Intermediate Similarity | NPC280852 |
0.7556 | Intermediate Similarity | NPC203754 |
0.7556 | Intermediate Similarity | NPC150048 |
0.7556 | Intermediate Similarity | NPC267885 |
0.7554 | Intermediate Similarity | NPC308931 |
0.7554 | Intermediate Similarity | NPC99939 |
0.7546 | Intermediate Similarity | NPC198988 |
0.7544 | Intermediate Similarity | NPC470823 |
0.7542 | Intermediate Similarity | NPC97525 |
0.7541 | Intermediate Similarity | NPC139291 |
0.7541 | Intermediate Similarity | NPC472108 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC176199 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.9568 | High Similarity | NPD3505 | Approved |
0.9568 | High Similarity | NPD3506 | Approved |
0.9509 | High Similarity | NPD4076 | Approved |
0.9509 | High Similarity | NPD4079 | Approved |
0.8963 | High Similarity | NPD4638 | Approved |
0.8963 | High Similarity | NPD4640 | Approved |
0.8963 | High Similarity | NPD4639 | Approved |
0.8862 | High Similarity | NPD4128 | Approved |
0.881 | High Similarity | NPD4075 | Phase 2 |
0.878 | High Similarity | NPD3323 | Discontinued |
0.8757 | High Similarity | NPD4181 | Approved |
0.8735 | High Similarity | NPD5069 | Clinical (unspecified phase) |
0.8571 | High Similarity | NPD3961 | Discontinued |
0.8521 | High Similarity | NPD3609 | Approved |
0.8521 | High Similarity | NPD3610 | Approved |
0.8509 | High Similarity | NPD3100 | Discontinued |
0.8503 | High Similarity | NPD5744 | Clinical (unspecified phase) |
0.8466 | Intermediate Similarity | NPD3486 | Clinical (unspecified phase) |
0.8421 | Intermediate Similarity | NPD5065 | Approved |
0.8324 | Intermediate Similarity | NPD6203 | Clinical (unspecified phase) |
0.8294 | Intermediate Similarity | NPD4779 | Clinical (unspecified phase) |
0.8294 | Intermediate Similarity | NPD5021 | Discontinued |
0.8282 | Intermediate Similarity | NPD4374 | Clinical (unspecified phase) |
0.8266 | Intermediate Similarity | NPD6375 | Clinical (unspecified phase) |
0.8256 | Intermediate Similarity | NPD4112 | Clinical (unspecified phase) |
0.8239 | Intermediate Similarity | NPD786 | Approved |
0.8232 | Intermediate Similarity | NPD4463 | Approved |
0.8232 | Intermediate Similarity | NPD4462 | Approved |
0.8148 | Intermediate Similarity | NPD5254 | Discontinued |
0.8137 | Intermediate Similarity | NPD1722 | Approved |
0.8114 | Intermediate Similarity | NPD2144 | Approved |
0.8098 | Intermediate Similarity | NPD6664 | Approved |
0.809 | Intermediate Similarity | NPD3607 | Clinical (unspecified phase) |
0.8079 | Intermediate Similarity | NPD3038 | Discontinued |
0.8056 | Intermediate Similarity | NPD8431 | Approved |
0.805 | Intermediate Similarity | NPD198 | Clinical (unspecified phase) |
0.8045 | Intermediate Similarity | NPD6610 | Clinical (unspecified phase) |
0.8035 | Intermediate Similarity | NPD4184 | Clinical (unspecified phase) |
0.8023 | Intermediate Similarity | NPD6595 | Phase 3 |
0.8012 | Intermediate Similarity | NPD2172 | Phase 1 |
0.7967 | Intermediate Similarity | NPD6281 | Approved |
0.7953 | Intermediate Similarity | NPD5315 | Discontinued |
0.7931 | Intermediate Similarity | NPD1325 | Approved |
0.7931 | Intermediate Similarity | NPD1326 | Approved |
0.7874 | Intermediate Similarity | NPD2640 | Approved |
0.7874 | Intermediate Similarity | NPD2641 | Approved |
0.7853 | Intermediate Similarity | NPD3943 | Clinical (unspecified phase) |
0.7838 | Intermediate Similarity | NPD5575 | Clinical (unspecified phase) |
0.7811 | Intermediate Similarity | NPD2837 | Discontinued |
0.7802 | Intermediate Similarity | NPD6217 | Discontinued |
0.7791 | Intermediate Similarity | NPD1403 | Approved |
0.7791 | Intermediate Similarity | NPD1404 | Approved |
0.7771 | Intermediate Similarity | NPD2185 | Clinical (unspecified phase) |
0.7725 | Intermediate Similarity | NPD1683 | Approved |
0.7717 | Intermediate Similarity | NPD8110 | Clinical (unspecified phase) |
0.7714 | Intermediate Similarity | NPD2639 | Approved |
0.7714 | Intermediate Similarity | NPD2642 | Approved |
0.7705 | Intermediate Similarity | NPD4426 | Clinical (unspecified phase) |
0.7688 | Intermediate Similarity | NPD3404 | Approved |
0.7684 | Intermediate Similarity | NPD5934 | Clinical (unspecified phase) |
0.7665 | Intermediate Similarity | NPD8094 | Discontinued |
0.766 | Intermediate Similarity | NPD2960 | Clinical (unspecified phase) |
0.7651 | Intermediate Similarity | NPD4637 | Clinical (unspecified phase) |
0.7644 | Intermediate Similarity | NPD1853 | Clinical (unspecified phase) |
0.7644 | Intermediate Similarity | NPD4511 | Phase 1 |
0.7641 | Intermediate Similarity | NPD2125 | Clinical (unspecified phase) |
0.7637 | Intermediate Similarity | NPD5728 | Clinical (unspecified phase) |
0.7624 | Intermediate Similarity | NPD6277 | Clinical (unspecified phase) |
0.7617 | Intermediate Similarity | NPD5901 | Discontinued |
0.7616 | Intermediate Similarity | NPD2580 | Discontinued |
0.7614 | Intermediate Similarity | NPD8093 | Discontinued |
0.7604 | Intermediate Similarity | NPD5721 | Clinical (unspecified phase) |
0.759 | Intermediate Similarity | NPD7947 | Clinical (unspecified phase) |
0.7574 | Intermediate Similarity | NPD4547 | Phase 3 |
0.7568 | Intermediate Similarity | NPD5590 | Clinical (unspecified phase) |
0.7557 | Intermediate Similarity | NPD4550 | Clinical (unspecified phase) |
0.7541 | Intermediate Similarity | NPD5106 | Approved |
0.7541 | Intermediate Similarity | NPD5105 | Approved |
0.754 | Intermediate Similarity | NPD6180 | Clinical (unspecified phase) |
0.7538 | Intermediate Similarity | NPD6838 | Clinical (unspecified phase) |
0.7526 | Intermediate Similarity | NPD7948 | Phase 1 |
0.7515 | Intermediate Similarity | NPD7469 | Discontinued |
0.7514 | Intermediate Similarity | NPD2748 | Clinical (unspecified phase) |
0.7513 | Intermediate Similarity | NPD7619 | Phase 3 |
0.7513 | Intermediate Similarity | NPD7618 | Phase 3 |
0.75 | Intermediate Similarity | NPD3583 | Phase 2 |
0.75 | Intermediate Similarity | NPD482 | Approved |
0.75 | Intermediate Similarity | NPD4615 | Phase 2 |
0.7487 | Intermediate Similarity | NPD5145 | Clinical (unspecified phase) |
0.7486 | Intermediate Similarity | NPD3117 | Approved |
0.7486 | Intermediate Similarity | NPD3116 | Approved |
0.7471 | Intermediate Similarity | NPD4702 | Approved |
0.7471 | Intermediate Similarity | NPD4703 | Approved |
0.7459 | Intermediate Similarity | NPD749 | Clinical (unspecified phase) |
0.7446 | Intermediate Similarity | NPD2092 | Phase 2 |
0.7446 | Intermediate Similarity | NPD2095 | Phase 2 |
0.7446 | Intermediate Similarity | NPD2094 | Phase 2 |
0.7409 | Intermediate Similarity | NPD8248 | Clinical (unspecified phase) |
0.7407 | Intermediate Similarity | NPD3475 | Approved |
0.7407 | Intermediate Similarity | NPD3476 | Approved |
0.7405 | Intermediate Similarity | NPD2096 | Phase 2 |
0.7405 | Intermediate Similarity | NPD2091 | Phase 2 |
0.7403 | Intermediate Similarity | NPD2928 | Phase 2 |
0.7398 | Intermediate Similarity | NPD7958 | Clinical (unspecified phase) |
0.7398 | Intermediate Similarity | NPD7957 | Phase 1 |
0.7385 | Intermediate Similarity | NPD8072 | Approved |
0.7378 | Intermediate Similarity | NPD4029 | Approved |
0.7378 | Intermediate Similarity | NPD3385 | Approved |
0.7378 | Intermediate Similarity | NPD4028 | Approved |
0.7378 | Intermediate Similarity | NPD4030 | Approved |
0.7363 | Intermediate Similarity | NPD5100 | Phase 3 |
0.736 | Intermediate Similarity | NPD2719 | Clinical (unspecified phase) |
0.736 | Intermediate Similarity | NPD2720 | Phase 1 |
0.7358 | Intermediate Similarity | NPD6661 | Clinical (unspecified phase) |
0.7356 | Intermediate Similarity | NPD977 | Approved |
0.7356 | Intermediate Similarity | NPD976 | Approved |
0.7356 | Intermediate Similarity | NPD975 | Approved |
0.7354 | Intermediate Similarity | NPD6630 | Clinical (unspecified phase) |
0.7349 | Intermediate Similarity | NPD1262 | Discovery |
0.7348 | Intermediate Similarity | NPD750 | Phase 2 |
0.7347 | Intermediate Similarity | NPD8272 | Phase 2 |
0.7341 | Intermediate Similarity | NPD2882 | Phase 1 |
0.7329 | Intermediate Similarity | NPD2118 | Approved |
0.7329 | Intermediate Similarity | NPD2119 | Approved |
0.731 | Intermediate Similarity | NPD4862 | Clinical (unspecified phase) |
0.7303 | Intermediate Similarity | NPD5138 | Approved |
0.7303 | Intermediate Similarity | NPD5140 | Approved |
0.7302 | Intermediate Similarity | NPD5117 | Phase 2 |
0.73 | Intermediate Similarity | NPD7470 | Discontinued |
0.7295 | Intermediate Similarity | NPD7271 | Approved |
0.7294 | Intermediate Similarity | NPD3813 | Approved |
0.7294 | Intermediate Similarity | NPD1918 | Clinical (unspecified phase) |
0.7287 | Intermediate Similarity | NPD2310 | Clinical (unspecified phase) |
0.7278 | Intermediate Similarity | NPD1592 | Phase 3 |
0.7278 | Intermediate Similarity | NPD2390 | Clinical (unspecified phase) |
0.7277 | Intermediate Similarity | NPD1304 | Clinical (unspecified phase) |
0.7273 | Intermediate Similarity | NPD7781 | Approved |
0.7273 | Intermediate Similarity | NPD3944 | Approved |
0.7273 | Intermediate Similarity | NPD3942 | Approved |
0.7273 | Intermediate Similarity | NPD7424 | Clinical (unspecified phase) |
0.7273 | Intermediate Similarity | NPD7780 | Approved |
0.7268 | Intermediate Similarity | NPD2381 | Approved |
0.7268 | Intermediate Similarity | NPD2380 | Approved |
0.7268 | Intermediate Similarity | NPD7621 | Clinical (unspecified phase) |
0.7268 | Intermediate Similarity | NPD2382 | Approved |
0.7264 | Intermediate Similarity | NPD3330 | Phase 1 |
0.7245 | Intermediate Similarity | NPD6975 | Discontinued |
0.7239 | Intermediate Similarity | NPD3654 | Approved |
0.7238 | Intermediate Similarity | NPD5436 | Phase 1 |
0.7232 | Intermediate Similarity | NPD5255 | Approved |
0.7232 | Intermediate Similarity | NPD3433 | Clinical (unspecified phase) |
0.7225 | Intermediate Similarity | NPD7730 | Approved |
0.7225 | Intermediate Similarity | NPD7731 | Approved |
0.7222 | Intermediate Similarity | NPD992 | Clinical (unspecified phase) |
0.7222 | Intermediate Similarity | NPD991 | Phase 2 |
0.7219 | Intermediate Similarity | NPD4957 | Phase 2 |
0.7216 | Intermediate Similarity | NPD2150 | Discontinued |
0.7214 | Intermediate Similarity | NPD4614 | Clinical (unspecified phase) |
0.7211 | Intermediate Similarity | NPD3871 | Clinical (unspecified phase) |
0.7211 | Intermediate Similarity | NPD3870 | Clinical (unspecified phase) |
0.7204 | Intermediate Similarity | NPD1895 | Discontinued |
0.7196 | Intermediate Similarity | NPD3002 | Clinical (unspecified phase) |
0.7192 | Intermediate Similarity | NPD8112 | Clinical (unspecified phase) |
0.7189 | Intermediate Similarity | NPD8386 | Phase 2 |
0.7188 | Intermediate Similarity | NPD802 | Phase 2 |
0.7188 | Intermediate Similarity | NPD1038 | Approved |
0.7186 | Intermediate Similarity | NPD8493 | Clinical (unspecified phase) |
0.7182 | Intermediate Similarity | NPD5862 | Discovery |
0.7172 | Intermediate Similarity | NPD5426 | Phase 3 |
0.7166 | Intermediate Similarity | NPD3320 | Approved |
0.7166 | Intermediate Similarity | NPD2391 | Clinical (unspecified phase) |
0.7166 | Intermediate Similarity | NPD3318 | Approved |
0.7166 | Intermediate Similarity | NPD5596 | Phase 2 |
0.7166 | Intermediate Similarity | NPD3319 | Phase 1 |
0.7165 | Intermediate Similarity | NPD3830 | Phase 1 |
0.7164 | Intermediate Similarity | NPD7998 | Clinical (unspecified phase) |
0.7164 | Intermediate Similarity | NPD4051 | Discontinued |
0.7157 | Intermediate Similarity | NPD8073 | Approved |
0.7156 | Intermediate Similarity | NPD7824 | Approved |
0.7151 | Intermediate Similarity | NPD5473 | Discontinued |
0.7151 | Intermediate Similarity | NPD8464 | Clinical (unspecified phase) |
0.7151 | Intermediate Similarity | NPD972 | Clinical (unspecified phase) |
0.715 | Intermediate Similarity | NPD7024 | Clinical (unspecified phase) |
0.7143 | Intermediate Similarity | NPD6476 | Clinical (unspecified phase) |
0.7143 | Intermediate Similarity | NPD6554 | Approved |
0.7143 | Intermediate Similarity | NPD6479 | Discontinued |
0.7143 | Intermediate Similarity | NPD6158 | Phase 2 |
0.7143 | Intermediate Similarity | NPD4601 | Approved |
0.7143 | Intermediate Similarity | NPD45 | Approved |
0.7143 | Intermediate Similarity | NPD4600 | Approved |
0.7135 | Intermediate Similarity | NPD3717 | Discontinued |
0.7135 | Intermediate Similarity | NPD2006 | Phase 2 |
0.7135 | Intermediate Similarity | NPD2007 | Clinical (unspecified phase) |
0.7129 | Intermediate Similarity | NPD5066 | Phase 2 |
0.7129 | Intermediate Similarity | NPD5067 | Phase 2 |
0.7128 | Intermediate Similarity | NPD7564 | Discontinued |
0.7126 | Intermediate Similarity | NPD4880 | Discontinued |
0.7126 | Intermediate Similarity | NPD2430 | Phase 2 |
0.712 | Intermediate Similarity | NPD4499 | Approved |
0.7119 | Intermediate Similarity | NPD3113 | Approved |
PubChem CID   | 440904 |
ChEMBL   | CHEMBL3706997 |
ZINC   |
Molecular Weight:   | 254.14 |
ALogP:   | -0.4921 |
MLogP:   | 2.89 |
XLogP:   | 1.098 |
# Rotatable Bonds:   | 3 |
Polar Surface Area:   | 39.26 |
# H-Bond Aceptor:   | 3 |
# H-Bond Donor:   | 2 |
# Rings:   | 4 |
# Heavy Atoms:   | 19 |