Natural Product: NPC97282

Natural Product ID:  NPC97282
Common Name:   Niazicin A
IUPAC Name:   [(2S,3R,4S,5R,6S)-4,5-dihydroxy-6-[4-[(methoxycarbothioylamino)methyl]phenoxy]-2-methyloxan-3-yl] acetate
Synonyms:  
Molecular Formula:   C17H23NO7S
Standard InCHIKey:  HMXLIRAHSHWREJ-QOYUQHOESA-N
Standard InCHI:  InChI=1S/C17H23NO7S/c1-9-15(24-10(2)19)13(20)14(21)16(23-9)25-12-6-4-11(5-7-12)8-18-17(26)22-3/h4-7,9,13-16,20-21H,8H2,1-3H3,(H,18,26)/t9-,13-,14+,15-,16-/m0/s1
Canonical SMILES:  COC(=NCc1ccc(cc1)O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)OC(=O)C)S
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO4858 Helipterum gnaphaloides Species Asteraceae Eukaryota UNPD*
NPO11021 Moringa oleifera Species Moringaceae Eukaryota UNPD*
NPO7266 Goupia glabra Species Goupiaceae Eukaryota UNPD*
NPO681 Mesua ferrea Species Calophyllaceae Eukaryota UNPD*
NPO5937 Garrya laurifolia Species Garryaceae Eukaryota UNPD*
NPO8339 Lithothamnion corallioides Species Hapalidiaceae Eukaryota UNPD*
NPO5536 Papaver persicum Species Papaveraceae Eukaryota UNPD*
NPO8703 Monopteryx uaucu Species Fabaceae Eukaryota UNPD*
NPO495 Daemonorops draco Species Arecaceae Eukaryota UNPD*
NPO4221 Fusarium sacchari Species Nectriaceae Eukaryota UNPD*
NPO3905 Medinilla magnifica Species Melastomataceae Eukaryota UNPD*
NPO1585 Onobrychis bobrovii Species Fabaceae Eukaryota UNPD*
NPO3302 Fusarium avenaceum Species Nectriaceae Eukaryota UNPD*
NPO6187 Sequoia sempervirens Species Cupressaceae Eukaryota UNPD*
NPO823 Senecio cathcartensis Species Asteraceae Eukaryota UNPD*
NPO7963 Excoecaria acerifolia Species Euphorbiaceae Eukaryota UNPD*
NPO2501 Trifolium strepens Species Fabaceae Eukaryota UNPD*
NPO5021 Podospora curvicolla Species Lasiosphaeriaceae Eukaryota UNPD*
NPO4410 Laggera alata Species Asteraceae Eukaryota UNPD*
NPO2703 Petteria ramentacea Species Fabaceae Eukaryota UNPD*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT113 Cell Line RAW264.7 Mus musculus IC50 > 45000 nM 20685125
NPT113 Cell Line RAW264.7 Mus musculus Inhibition = 17.3 % 20685125

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC97282 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.9781 High Similarity NPC136951
0.9781 High Similarity NPC161155
0.9781 High Similarity NPC97004
0.9632 High Similarity NPC298821
0.942 High Similarity NPC123761
0.9416 High Similarity NPC36434
0.8421 Intermediate Similarity NPC18249
0.8421 Intermediate Similarity NPC305700
0.8421 Intermediate Similarity NPC197741
0.8421 Intermediate Similarity NPC10221
0.8421 Intermediate Similarity NPC187028
0.8421 Intermediate Similarity NPC140915
0.8298 Intermediate Similarity NPC295970
0.8243 Intermediate Similarity NPC63628
0.8243 Intermediate Similarity NPC178466
0.8231 Intermediate Similarity NPC195814
0.8175 Intermediate Similarity NPC469412
0.8175 Intermediate Similarity NPC198734
0.8158 Intermediate Similarity NPC114659
0.8158 Intermediate Similarity NPC139699
0.8156 Intermediate Similarity NPC198798
0.8102 Intermediate Similarity NPC60589
0.8102 Intermediate Similarity NPC469708
0.8043 Intermediate Similarity NPC269242
0.8014 Intermediate Similarity NPC471029
0.8013 Intermediate Similarity NPC313414
0.7943 Intermediate Similarity NPC287429
0.7929 Intermediate Similarity NPC476142
0.7905 Intermediate Similarity NPC37468
0.7852 Intermediate Similarity NPC124149
0.7847 Intermediate Similarity NPC302378
0.7847 Intermediate Similarity NPC146540
0.78 Intermediate Similarity NPC100389
0.7793 Intermediate Similarity NPC248355
0.7793 Intermediate Similarity NPC270849
0.7793 Intermediate Similarity NPC26653
0.7785 Intermediate Similarity NPC166180
0.777 Intermediate Similarity NPC14950
0.777 Intermediate Similarity NPC34456
0.774 Intermediate Similarity NPC80600
0.774 Intermediate Similarity NPC472024
0.773 Intermediate Similarity NPC226712
0.7718 Intermediate Similarity NPC185778
0.7718 Intermediate Similarity NPC55040
0.7676 Intermediate Similarity NPC52097
0.7671 Intermediate Similarity NPC166040
0.7667 Intermediate Similarity NPC103409
0.7667 Intermediate Similarity NPC157554
0.7667 Intermediate Similarity NPC186418
0.7647 Intermediate Similarity NPC157816
0.7639 Intermediate Similarity NPC470510
0.7635 Intermediate Similarity NPC269421
0.7635 Intermediate Similarity NPC162093
0.7632 Intermediate Similarity NPC202700
0.7619 Intermediate Similarity NPC474491
0.7606 Intermediate Similarity NPC11724
0.7597 Intermediate Similarity NPC478239
0.7597 Intermediate Similarity NPC469367
0.7586 Intermediate Similarity NPC471157
0.7584 Intermediate Similarity NPC49074
0.7584 Intermediate Similarity NPC115022
0.7584 Intermediate Similarity NPC25821
0.7584 Intermediate Similarity NPC294166
0.7582 Intermediate Similarity NPC186406
0.7582 Intermediate Similarity NPC80098
0.7582 Intermediate Similarity NPC215512
0.7582 Intermediate Similarity NPC476442
0.7568 Intermediate Similarity NPC9912
0.7568 Intermediate Similarity NPC121376
0.7566 Intermediate Similarity NPC226005
0.7554 Intermediate Similarity NPC175771
0.7551 Intermediate Similarity NPC307110
0.7551 Intermediate Similarity NPC97326
0.755 Intermediate Similarity NPC294470
0.7548 Intermediate Similarity NPC471028
0.7536 Intermediate Similarity NPC313193
0.7535 Intermediate Similarity NPC476872
0.7534 Intermediate Similarity NPC156692
0.7534 Intermediate Similarity NPC45224
0.7534 Intermediate Similarity NPC106677
0.7534 Intermediate Similarity NPC471882
0.7534 Intermediate Similarity NPC471881
0.7534 Intermediate Similarity NPC173150
0.7534 Intermediate Similarity NPC35288
0.7533 Intermediate Similarity NPC187194
0.7532 Intermediate Similarity NPC145319
0.7517 Intermediate Similarity NPC85799
0.7517 Intermediate Similarity NPC12308
0.7517 Intermediate Similarity NPC83218
0.7517 Intermediate Similarity NPC165686
0.7517 Intermediate Similarity NPC303422
0.7517 Intermediate Similarity NPC126991
0.7517 Intermediate Similarity NPC26080
0.7516 Intermediate Similarity NPC471032
0.7516 Intermediate Similarity NPC470935
0.7516 Intermediate Similarity NPC210478
0.75 Intermediate Similarity NPC212176
0.75 Intermediate Similarity NPC85624
0.75 Intermediate Similarity NPC226722
0.7483 Intermediate Similarity NPC238243
0.7483 Intermediate Similarity NPC212729
0.7483 Intermediate Similarity NPC470236
0.7468 Intermediate Similarity NPC79908
0.7467 Intermediate Similarity NPC69513
0.7467 Intermediate Similarity NPC215833
0.7466 Intermediate Similarity NPC252114
0.7466 Intermediate Similarity NPC233559
0.7456 Intermediate Similarity NPC49353
0.7452 Intermediate Similarity NPC277857
0.7452 Intermediate Similarity NPC74320
0.7452 Intermediate Similarity NPC291153
0.7452 Intermediate Similarity NPC199928
0.7452 Intermediate Similarity NPC115144
0.7452 Intermediate Similarity NPC107120
0.7452 Intermediate Similarity NPC476865
0.745 Intermediate Similarity NPC225384
0.745 Intermediate Similarity NPC248307
0.745 Intermediate Similarity NPC138777
0.745 Intermediate Similarity NPC246869
0.745 Intermediate Similarity NPC470392
0.745 Intermediate Similarity NPC65942
0.7448 Intermediate Similarity NPC62101
0.7448 Intermediate Similarity NPC95733
0.7447 Intermediate Similarity NPC101503
0.7436 Intermediate Similarity NPC232228
0.7436 Intermediate Similarity NPC292443
0.7436 Intermediate Similarity NPC476867
0.7434 Intermediate Similarity NPC164857
0.7434 Intermediate Similarity NPC138350
0.7434 Intermediate Similarity NPC40664
0.7434 Intermediate Similarity NPC3293
0.7434 Intermediate Similarity NPC165482
0.7434 Intermediate Similarity NPC197723
0.7432 Intermediate Similarity NPC253595
0.7432 Intermediate Similarity NPC218003
0.7429 Intermediate Similarity NPC148055
0.7419 Intermediate Similarity NPC140502
0.7417 Intermediate Similarity NPC48863
0.7417 Intermediate Similarity NPC188555
0.7417 Intermediate Similarity NPC130496
0.7417 Intermediate Similarity NPC13745
0.7417 Intermediate Similarity NPC476411
0.7417 Intermediate Similarity NPC251981
0.7415 Intermediate Similarity NPC288416
0.741 Intermediate Similarity NPC198741
0.7405 Intermediate Similarity NPC296377
0.7405 Intermediate Similarity NPC97240
0.7405 Intermediate Similarity NPC175275
0.7405 Intermediate Similarity NPC87950
0.7405 Intermediate Similarity NPC471764
0.74 Intermediate Similarity NPC299144
0.74 Intermediate Similarity NPC252833
0.7397 Intermediate Similarity NPC29477
0.7389 Intermediate Similarity NPC476868
0.7389 Intermediate Similarity NPC476869
0.7389 Intermediate Similarity NPC476864
0.7389 Intermediate Similarity NPC476866
0.7386 Intermediate Similarity NPC470413
0.7386 Intermediate Similarity NPC262328
0.7386 Intermediate Similarity NPC138738
0.7386 Intermediate Similarity NPC87777
0.7383 Intermediate Similarity NPC262606
0.7372 Intermediate Similarity NPC237872
0.7372 Intermediate Similarity NPC116104
0.7372 Intermediate Similarity NPC263397
0.7372 Intermediate Similarity NPC152796
0.7372 Intermediate Similarity NPC475213
0.7372 Intermediate Similarity NPC302286
0.7372 Intermediate Similarity NPC242756
0.7372 Intermediate Similarity NPC88754
0.7368 Intermediate Similarity NPC79957
0.7365 Intermediate Similarity NPC198487
0.7365 Intermediate Similarity NPC40377
0.7365 Intermediate Similarity NPC225307
0.7358 Intermediate Similarity NPC95990
0.7358 Intermediate Similarity NPC169510
0.7358 Intermediate Similarity NPC96294
0.7358 Intermediate Similarity NPC220282
0.7358 Intermediate Similarity NPC93924
0.7358 Intermediate Similarity NPC182119
0.7358 Intermediate Similarity NPC478237
0.7351 Intermediate Similarity NPC6836
0.7351 Intermediate Similarity NPC469449
0.7351 Intermediate Similarity NPC132895
0.7347 Intermediate Similarity NPC61181
0.7343 Intermediate Similarity NPC263835
0.7342 Intermediate Similarity NPC476743
0.7338 Intermediate Similarity NPC212770
0.7338 Intermediate Similarity NPC98777
0.7333 Intermediate Similarity NPC281798
0.7333 Intermediate Similarity NPC29734
0.7333 Intermediate Similarity NPC46137
0.7333 Intermediate Similarity NPC254819
0.7333 Intermediate Similarity NPC235294
0.7329 Intermediate Similarity NPC270811
0.7329 Intermediate Similarity NPC471073
0.7325 Intermediate Similarity NPC110063
0.7325 Intermediate Similarity NPC297342
0.7325 Intermediate Similarity NPC478240
0.732 Intermediate Similarity NPC242028

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC97282 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.773 Intermediate Similarity NPD1091 Approved
0.7682 Intermediate Similarity NPD3656 Approved
0.75 Intermediate Similarity NPD3685 Discontinued
0.7452 Intermediate Similarity NPD4123 Phase 3
0.7452 Intermediate Similarity NPD3536 Discontinued
0.7451 Intermediate Similarity NPD1375 Discontinued
0.7421 Intermediate Similarity NPD3686 Approved
0.7421 Intermediate Similarity NPD3687 Approved
0.7346 Intermediate Similarity NPD4433 Discontinued
0.7329 Intermediate Similarity NPD4675 Approved
0.7329 Intermediate Similarity NPD4678 Approved
0.7314 Intermediate Similarity NPD6841 Approved
0.7314 Intermediate Similarity NPD6842 Approved
0.7314 Intermediate Similarity NPD6843 Phase 3
0.7296 Intermediate Similarity NPD4186 Clinical (unspecified phase)
0.7273 Intermediate Similarity NPD5604 Discontinued
0.7267 Intermediate Similarity NPD1048 Approved
0.7244 Intermediate Similarity NPD1652 Phase 2
0.72 Intermediate Similarity NPD3179 Approved
0.72 Intermediate Similarity NPD3180 Approved
0.7179 Intermediate Similarity NPD2030 Discontinued
0.7152 Intermediate Similarity NPD3145 Approved
0.7152 Intermediate Similarity NPD3144 Approved
0.7125 Intermediate Similarity NPD4739 Approved
0.7117 Intermediate Similarity NPD6502 Phase 2
0.7107 Intermediate Similarity NPD6667 Approved
0.7107 Intermediate Similarity NPD6666 Approved
0.7105 Intermediate Similarity NPD5745 Approved
0.7105 Intermediate Similarity NPD7477 Discontinued
0.7105 Intermediate Similarity NPD2674 Phase 3
0.7099 Intermediate Similarity NPD1653 Approved
0.7097 Intermediate Similarity NPD4108 Discontinued
0.7091 Intermediate Similarity NPD5772 Approved
0.7091 Intermediate Similarity NPD5773 Approved
0.7086 Intermediate Similarity NPD5163 Phase 2
0.707 Intermediate Similarity NPD7153 Discontinued
0.707 Intermediate Similarity NPD7596 Clinical (unspecified phase)
0.7051 Intermediate Similarity NPD2239 Approved
0.7051 Intermediate Similarity NPD2240 Approved
0.7025 Intermediate Similarity NPD2976 Clinical (unspecified phase)
0.7011 Intermediate Similarity NPD7007 Discovery
0.7006 Intermediate Similarity NPD7266 Discontinued
0.7 Intermediate Similarity NPD5756 Phase 2
0.7 Intermediate Similarity NPD5295 Discontinued
0.6994 Remote Similarity NPD4003 Phase 3
0.6993 Remote Similarity NPD6233 Phase 2
0.6993 Remote Similarity NPD4062 Phase 3
0.6988 Remote Similarity NPD2977 Approved
0.6988 Remote Similarity NPD2978 Approved
0.6988 Remote Similarity NPD7972 Discontinued
0.6988 Remote Similarity NPD8455 Phase 2
0.6987 Remote Similarity NPD3693 Clinical (unspecified phase)
0.6982 Remote Similarity NPD5677 Discontinued
0.6978 Remote Similarity NPD2684 Approved
0.6974 Remote Similarity NPD5746 Approved
0.697 Remote Similarity NPD7615 Clinical (unspecified phase)
0.6968 Remote Similarity NPD3052 Approved
0.6968 Remote Similarity NPD3054 Approved
0.6964 Remote Similarity NPD7975 Clinical (unspecified phase)
0.6946 Remote Similarity NPD2560 Approved
0.6946 Remote Similarity NPD2563 Approved
0.6943 Remote Similarity NPD3175 Clinical (unspecified phase)
0.6943 Remote Similarity NPD6032 Approved
0.6943 Remote Similarity NPD2161 Phase 2
0.6933 Remote Similarity NPD3568 Approved
0.6933 Remote Similarity NPD3567 Approved
0.6928 Remote Similarity NPD3374 Clinical (unspecified phase)
0.6923 Remote Similarity NPD7097 Phase 1
0.6918 Remote Similarity NPD2595 Approved
0.6918 Remote Similarity NPD4162 Approved
0.6918 Remote Similarity NPD2594 Approved
0.6918 Remote Similarity NPD6364 Approved
0.6918 Remote Similarity NPD44 Approved
0.6913 Remote Similarity NPD3676 Clinical (unspecified phase)
0.6908 Remote Similarity NPD2614 Approved
0.6906 Remote Similarity NPD1358 Approved
0.6906 Remote Similarity NPD290 Approved
0.6903 Remote Similarity NPD4340 Discontinued
0.6901 Remote Similarity NPD7843 Approved
0.6899 Remote Similarity NPD521 Clinical (unspecified phase)
0.6894 Remote Similarity NPD5058 Phase 3
0.6892 Remote Similarity NPD776 Approved
0.6887 Remote Similarity NPD558 Phase 2
0.6886 Remote Similarity NPD5563 Clinical (unspecified phase)
0.6886 Remote Similarity NPD3465 Clinical (unspecified phase)
0.6882 Remote Similarity NPD4666 Phase 3
0.6875 Remote Similarity NPD6331 Phase 2
0.6871 Remote Similarity NPD7526 Approved
0.6871 Remote Similarity NPD7527 Clinical (unspecified phase)
0.6871 Remote Similarity NPD52 Approved
0.6871 Remote Similarity NPD7314 Clinical (unspecified phase)
0.6859 Remote Similarity NPD1772 Clinical (unspecified phase)
0.6859 Remote Similarity NPD2653 Approved
0.6855 Remote Similarity NPD2424 Discontinued
0.6846 Remote Similarity NPD2235 Phase 2
0.6846 Remote Similarity NPD2231 Phase 2
0.6839 Remote Similarity NPD2238 Phase 2
0.6832 Remote Similarity NPD2677 Approved
0.6826 Remote Similarity NPD4018 Clinical (unspecified phase)
0.6824 Remote Similarity NPD5709 Phase 3
0.6821 Remote Similarity NPD1817 Approved
0.6821 Remote Similarity NPD1820 Approved
0.6821 Remote Similarity NPD1819 Approved
0.6821 Remote Similarity NPD1818 Approved
0.6818 Remote Similarity NPD6798 Discontinued
0.6818 Remote Similarity NPD3056 Clinical (unspecified phase)
0.6818 Remote Similarity NPD6859 Clinical (unspecified phase)
0.6813 Remote Similarity NPD3060 Approved
0.6813 Remote Similarity NPD4237 Approved
0.6813 Remote Similarity NPD2460 Phase 3
0.6813 Remote Similarity NPD4236 Phase 3
0.6813 Remote Similarity NPD2459 Approved
0.6813 Remote Similarity NPD2458 Approved
0.681 Remote Similarity NPD6419 Discontinued
0.6809 Remote Similarity NPD6669 Phase 2
0.6802 Remote Similarity NPD6071 Discontinued
0.6802 Remote Similarity NPD7315 Approved
0.68 Remote Similarity NPD4129 Approved
0.6797 Remote Similarity NPD5752 Clinical (unspecified phase)
0.6792 Remote Similarity NPD5865 Clinical (unspecified phase)
0.6789 Remote Similarity NPD7583 Approved
0.6786 Remote Similarity NPD6818 Clinical (unspecified phase)
0.6784 Remote Similarity NPD2042 Clinical (unspecified phase)
0.6784 Remote Similarity NPD2904 Discontinued
0.6784 Remote Similarity NPD2041 Clinical (unspecified phase)
0.6783 Remote Similarity NPD821 Approved
0.6774 Remote Similarity NPD840 Approved
0.6774 Remote Similarity NPD1423 Approved
0.6774 Remote Similarity NPD839 Approved
0.677 Remote Similarity NPD4628 Phase 3
0.6768 Remote Similarity NPD6390 Discontinued
0.6766 Remote Similarity NPD6072 Discontinued
0.6765 Remote Similarity NPD8031 Discontinued
0.6761 Remote Similarity NPD5557 Phase 1
0.6759 Remote Similarity NPD7157 Approved
0.6757 Remote Similarity NPD2668 Approved
0.6757 Remote Similarity NPD2667 Approved
0.6754 Remote Similarity NPD7585 Approved
0.6753 Remote Similarity NPD3165 Approved
0.6753 Remote Similarity NPD3166 Approved
0.6753 Remote Similarity NPD3167 Approved
0.6753 Remote Similarity NPD3164 Approved
0.6752 Remote Similarity NPD2492 Phase 1
0.6748 Remote Similarity NPD2752 Clinical (unspecified phase)
0.6748 Remote Similarity NPD7212 Phase 2
0.6748 Remote Similarity NPD7213 Phase 3
0.6747 Remote Similarity NPD8158 Clinical (unspecified phase)
0.6743 Remote Similarity NPD3909 Discontinued
0.6731 Remote Similarity NPD5837 Clinical (unspecified phase)
0.673 Remote Similarity NPD3156 Discontinued
0.6728 Remote Similarity NPD5307 Clinical (unspecified phase)
0.6727 Remote Similarity NPD2122 Discontinued
0.6726 Remote Similarity NPD5356 Approved
0.6726 Remote Similarity NPD7945 Clinical (unspecified phase)
0.6726 Remote Similarity NPD5355 Approved
0.6726 Remote Similarity NPD5720 Discontinued
0.6723 Remote Similarity NPD3823 Discontinued
0.6714 Remote Similarity NPD3134 Approved
0.6711 Remote Similarity NPD3847 Discontinued
0.6709 Remote Similarity NPD4536 Approved
0.6709 Remote Similarity NPD696 Discontinued
0.6709 Remote Similarity NPD4537 Clinical (unspecified phase)
0.6709 Remote Similarity NPD4538 Approved
0.6708 Remote Similarity NPD5289 Phase 2
0.6708 Remote Similarity NPD5698 Clinical (unspecified phase)
0.6708 Remote Similarity NPD6674 Discontinued
0.6707 Remote Similarity NPD681 Clinical (unspecified phase)
0.6706 Remote Similarity NPD7773 Phase 2
0.669 Remote Similarity NPD556 Approved
0.6689 Remote Similarity NPD1357 Approved
0.6689 Remote Similarity NPD6583 Phase 3
0.6689 Remote Similarity NPD6582 Phase 2
0.6689 Remote Similarity NPD6382 Discontinued
0.6688 Remote Similarity NPD5124 Phase 1
0.6688 Remote Similarity NPD5123 Clinical (unspecified phase)
0.6688 Remote Similarity NPD6355 Discontinued
0.6687 Remote Similarity NPD3122 Phase 3
0.6687 Remote Similarity NPD4210 Discontinued
0.6686 Remote Similarity NPD7089 Clinical (unspecified phase)
0.6685 Remote Similarity NPD5192 Clinical (unspecified phase)
0.6685 Remote Similarity NPD7038 Approved
0.6685 Remote Similarity NPD7039 Approved
0.6667 Remote Similarity NPD2388 Discontinued
0.6667 Remote Similarity NPD4381 Clinical (unspecified phase)
0.6667 Remote Similarity NPD5261 Clinical (unspecified phase)
0.6667 Remote Similarity NPD4773 Phase 2
0.6667 Remote Similarity NPD2216 Approved
0.6667 Remote Similarity NPD6658 Clinical (unspecified phase)
0.6667 Remote Similarity NPD3152 Clinical (unspecified phase)
0.6667 Remote Similarity NPD3705 Approved
0.6667 Remote Similarity NPD2215 Approved
0.6667 Remote Similarity NPD5535 Approved
0.6667 Remote Similarity NPD6380 Phase 1
0.6667 Remote Similarity NPD3058 Clinical (unspecified phase)
0.6667 Remote Similarity NPD422 Phase 1
0.6667 Remote Similarity NPD4772 Phase 2
0.6647 Remote Similarity NPD2415 Discontinued
0.6647 Remote Similarity NPD5811 Approved
0.6647 Remote Similarity NPD6063 Approved
0.6647 Remote Similarity NPD4005 Discontinued

Structure

External Identifiers

PubChem CID   10068657
ChEMBL   CHEMBL1223971
ZINC  

Physicochemical Properties

Molecular Weight:  385.12
ALogP:  -0.3419
MLogP:  2.34
XLogP:  1.819
# Rotatable Bonds:  13
Polar Surface Area:  145.61
# H-Bond Aceptor:  7
# H-Bond Donor:  2
# Rings:  2
# Heavy Atoms:  26

Download Data

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General Info & Identifiers & Properties  
Structure MOL file  
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Biological Activities  
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