NPASS Natural Product

Natural Product: NPC473967

Natural Product ID:	NPC473967
Common Name:	Arugosin F
IUPAC Name:	1,6,10-trihydroxy-8-methyl-6H-benzo[c][1]benzoxepin-11-one
Synonyms:	Arugosin F
Molecular Formula:	C15H12O5
Standard InCHIKey:	JLEOTFZRJGKSAD-UHFFFAOYSA-N
Standard InCHI:	InChI=1S/C15H12O5/c1-7-5-8-12(10(17)6-7)14(18)13-9(16)3-2-4-11(13)20-15(8)19/h2-6,15-17,19H,1H3
Canonical SMILES:	Cc1cc2C(O)Oc3c(C(=O)c2c(c1)O)c(O)ccc3
First Find Year:
Max Developmental Stage:
Synthetic Gene Cluster:	;

Species Source

Organism ID	Organism Name	Taxonomy Level	Family	SuperKingdom	Isolation Part	Collection Location	Collection Time	Reference
NPO23356	Ascodesmis sphaerospora	Species	Ascodesmidaceae	Eukaryota				PMID[9868168]

Biological Activity

Activity Type	# Activity
Others	4

Activity Type	# Activity
Organism	4

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	IZ	=	15	mm	22440624
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IZ	=	7	mm	22440624
NPT3096	Organism	Ascobolus	Ascobolus	Inhibition	=	100	%	23398362
NPT3095	Organism	Sordaria fimicola	Sordaria fimicola	Activity	=	50	%	22683112

Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

● The left chart: Distribution of similarity level between NPC473967 and all remaining natural products in the NPASS database.
● The right table: Most similar natural products (Tc>=0.56 or Top200).

range	Tanimoto Coefficient
0-0.1	286
0.1-0.2	1218
0.2-0.3	2331
0.3-0.4	5725
0.4-0.5	7708
0.5-0.6	2596
0.6-0.7	4411
0.7-0.8	5011
0.8-0.85	1470
0.85-0.9	127
0.9-0.95	6
0.95-1	0

Similarity Score	Similarity Level	Natural Product ID
0.9456	High Similarity	NPC5537
0.9388	High Similarity	NPC71055
0.9073	High Similarity	NPC202595
0.902	High Similarity	NPC135522
0.9013	High Similarity	NPC39819
0.9007	High Similarity	NPC70764
0.8954	High Similarity	NPC281272
0.8947	High Similarity	NPC325983
0.8861	High Similarity	NPC216752
0.8831	High Similarity	NPC273483
0.8812	High Similarity	NPC178851
0.879	High Similarity	NPC186113
0.875	High Similarity	NPC7943
0.875	High Similarity	NPC22005
0.875	High Similarity	NPC123202
0.8742	High Similarity	NPC278329
0.8742	High Similarity	NPC146837
0.8726	High Similarity	NPC44199
0.8716	High Similarity	NPC268691
0.8712	High Similarity	NPC111536
0.8712	High Similarity	NPC76128
0.8712	High Similarity	NPC30432
0.8712	High Similarity	NPC5029
0.8712	High Similarity	NPC271385
0.871	High Similarity	NPC40356
0.871	High Similarity	NPC271681
0.871	High Similarity	NPC154683
0.8704	High Similarity	NPC259905
0.8701	High Similarity	NPC147735
0.8701	High Similarity	NPC255641
0.8701	High Similarity	NPC290954
0.8701	High Similarity	NPC119929
0.8693	High Similarity	NPC7025
0.8693	High Similarity	NPC256672
0.8693	High Similarity	NPC27221
0.8667	High Similarity	NPC94076
0.8667	High Similarity	NPC475246
0.8667	High Similarity	NPC182255
0.8659	High Similarity	NPC98776
0.8654	High Similarity	NPC210942
0.8654	High Similarity	NPC169990
0.865	High Similarity	NPC298778
0.8645	High Similarity	NPC72958
0.8645	High Similarity	NPC478148
0.8645	High Similarity	NPC232645
0.8645	High Similarity	NPC149526
0.8645	High Similarity	NPC474417
0.8645	High Similarity	NPC175617
0.8645	High Similarity	NPC318424
0.8636	High Similarity	NPC158338
0.8636	High Similarity	NPC97029
0.8636	High Similarity	NPC291049
0.8636	High Similarity	NPC288036
0.8636	High Similarity	NPC233267
0.8636	High Similarity	NPC97028
0.8636	High Similarity	NPC65589
0.8636	High Similarity	NPC100985
0.8634	High Similarity	NPC178281
0.8625	High Similarity	NPC473961
0.8625	High Similarity	NPC212099
0.8625	High Similarity	NPC101116
0.8618	High Similarity	NPC469764
0.8609	High Similarity	NPC84266
0.8608	High Similarity	NPC96342
0.8608	High Similarity	NPC212967
0.8608	High Similarity	NPC246647
0.8608	High Similarity	NPC164110
0.8606	High Similarity	NPC3718
0.8606	High Similarity	NPC68381
0.86	High Similarity	NPC145673
0.8599	High Similarity	NPC87404
0.8599	High Similarity	NPC92395
0.8598	High Similarity	NPC260263
0.859	High Similarity	NPC471349
0.859	High Similarity	NPC474843
0.859	High Similarity	NPC87708
0.859	High Similarity	NPC471347
0.8589	High Similarity	NPC222455
0.8581	High Similarity	NPC227122
0.8581	High Similarity	NPC470107
0.8571	High Similarity	NPC228012
0.8571	High Similarity	NPC105415
0.8563	High Similarity	NPC470091
0.8563	High Similarity	NPC153578
0.8563	High Similarity	NPC299149
0.8563	High Similarity	NPC240887
0.8563	High Similarity	NPC114257
0.8563	High Similarity	NPC277710
0.8563	High Similarity	NPC329161
0.8562	High Similarity	NPC99454
0.8562	High Similarity	NPC469758
0.8562	High Similarity	NPC225173
0.8562	High Similarity	NPC300540
0.8562	High Similarity	NPC163846
0.8562	High Similarity	NPC130176
0.8554	High Similarity	NPC475233
0.8554	High Similarity	NPC46958
0.8545	High Similarity	NPC213052
0.8545	High Similarity	NPC85368
0.8544	High Similarity	NPC211482
0.8544	High Similarity	NPC146211
0.8544	High Similarity	NPC180924
0.8544	High Similarity	NPC476652
0.8537	High Similarity	NPC241874
0.8535	High Similarity	NPC168805
0.8535	High Similarity	NPC193200
0.8535	High Similarity	NPC329844
0.8535	High Similarity	NPC121910
0.8528	High Similarity	NPC63470
0.8526	High Similarity	NPC470569
0.8526	High Similarity	NPC46564
0.8526	High Similarity	NPC133856
0.8526	High Similarity	NPC207346
0.8526	High Similarity	NPC258249
0.8519	High Similarity	NPC112981
0.8516	High Similarity	NPC73236
0.8516	High Similarity	NPC10027
0.8516	High Similarity	NPC65775
0.8512	High Similarity	NPC477860
0.8512	High Similarity	NPC475161
0.8506	High Similarity	NPC245584
0.8506	High Similarity	NPC126767
0.8506	High Similarity	NPC190648
0.8506	High Similarity	NPC118027
0.8506	High Similarity	NPC289042
0.8506	High Similarity	NPC56433
0.8506	High Similarity	NPC308200
0.8506	High Similarity	NPC471734
0.8506	High Similarity	NPC125801
0.8506	High Similarity	NPC146884
0.8506	High Similarity	NPC312929
0.85	High Similarity	NPC143050
0.85	High Similarity	NPC470810
0.8494	Intermediate Similarity	NPC470454
0.8494	Intermediate Similarity	NPC474345
0.8494	Intermediate Similarity	NPC199533
0.8491	Intermediate Similarity	NPC177742
0.8487	Intermediate Similarity	NPC310340
0.8481	Intermediate Similarity	NPC149618
0.8481	Intermediate Similarity	NPC89625
0.8481	Intermediate Similarity	NPC148938
0.8477	Intermediate Similarity	NPC275734
0.8476	Intermediate Similarity	NPC473202
0.8476	Intermediate Similarity	NPC246274
0.8471	Intermediate Similarity	NPC175978
0.8471	Intermediate Similarity	NPC321363
0.8471	Intermediate Similarity	NPC253904
0.8471	Intermediate Similarity	NPC217447
0.8467	Intermediate Similarity	NPC18457
0.8467	Intermediate Similarity	NPC1268
0.8466	Intermediate Similarity	NPC178173
0.8466	Intermediate Similarity	NPC20216
0.8462	Intermediate Similarity	NPC295036
0.8462	Intermediate Similarity	NPC37348
0.8462	Intermediate Similarity	NPC158866
0.8462	Intermediate Similarity	NPC470568
0.8462	Intermediate Similarity	NPC294646
0.8462	Intermediate Similarity	NPC13282
0.8457	Intermediate Similarity	NPC156082
0.8457	Intermediate Similarity	NPC470772
0.8452	Intermediate Similarity	NPC39195
0.8452	Intermediate Similarity	NPC145467
0.8452	Intermediate Similarity	NPC212290
0.8452	Intermediate Similarity	NPC172329
0.8452	Intermediate Similarity	NPC37139
0.8452	Intermediate Similarity	NPC2569
0.8442	Intermediate Similarity	NPC24136
0.8442	Intermediate Similarity	NPC187282
0.8442	Intermediate Similarity	NPC471735
0.8442	Intermediate Similarity	NPC290133
0.8442	Intermediate Similarity	NPC472629
0.8438	Intermediate Similarity	NPC85121
0.8438	Intermediate Similarity	NPC324736
0.8434	Intermediate Similarity	NPC472054
0.8431	Intermediate Similarity	NPC19896
0.8431	Intermediate Similarity	NPC113770
0.8424	Intermediate Similarity	NPC239440
0.8424	Intermediate Similarity	NPC20543
0.8424	Intermediate Similarity	NPC17219
0.8421	Intermediate Similarity	NPC49108
0.8418	Intermediate Similarity	NPC158261
0.8418	Intermediate Similarity	NPC208806
0.8418	Intermediate Similarity	NPC95842
0.8418	Intermediate Similarity	NPC214632
0.8418	Intermediate Similarity	NPC178964
0.8418	Intermediate Similarity	NPC280530
0.8418	Intermediate Similarity	NPC477691
0.8418	Intermediate Similarity	NPC235333
0.8418	Intermediate Similarity	NPC42458
0.8415	Intermediate Similarity	NPC471288
0.8415	Intermediate Similarity	NPC225419
0.8411	Intermediate Similarity	NPC165172
0.8408	Intermediate Similarity	NPC471289
0.8408	Intermediate Similarity	NPC471291
0.8408	Intermediate Similarity	NPC470771
0.8408	Intermediate Similarity	NPC115324
0.8397	Intermediate Similarity	NPC471114
0.8397	Intermediate Similarity	NPC269420
0.8397	Intermediate Similarity	NPC329933
0.8397	Intermediate Similarity	NPC266499

Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

● The left chart: Distribution of similarity level between NPC473967 and all drugs/candidates.
● The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

range	Tanimoto Coefficient
0-0.1	306
0.1-0.2	916
0.2-0.3	1584
0.3-0.4	2590
0.4-0.5	1989
0.5-0.6	1152
0.6-0.7	410
0.7-0.8	186
0.8-0.85	28
0.85-0.9	0
0.9-0.95	0
0.95-1	0

Similarity Score	Similarity Level	Drug ID	Developmental Stage
0.8333	Intermediate Similarity	NPD1551	Phase 2
0.8323	Intermediate Similarity	NPD6559	Discontinued
0.8302	Intermediate Similarity	NPD7819	Suspended
0.828	Intermediate Similarity	NPD3226	Approved
0.8278	Intermediate Similarity	NPD2346	Discontinued
0.8258	Intermediate Similarity	NPD2533	Approved
0.8258	Intermediate Similarity	NPD2534	Approved
0.8258	Intermediate Similarity	NPD4378	Clinical (unspecified phase)
0.8258	Intermediate Similarity	NPD2532	Approved
0.8235	Intermediate Similarity	NPD1878	Clinical (unspecified phase)
0.8221	Intermediate Similarity	NPD6959	Discontinued
0.8187	Intermediate Similarity	NPD2393	Clinical (unspecified phase)
0.8158	Intermediate Similarity	NPD1550	Clinical (unspecified phase)
0.8158	Intermediate Similarity	NPD1552	Clinical (unspecified phase)
0.8148	Intermediate Similarity	NPD4381	Clinical (unspecified phase)
0.8133	Intermediate Similarity	NPD1607	Approved
0.8118	Intermediate Similarity	NPD8313	Approved
0.8118	Intermediate Similarity	NPD8312	Approved
0.8105	Intermediate Similarity	NPD970	Clinical (unspecified phase)
0.8105	Intermediate Similarity	NPD1549	Phase 2
0.8084	Intermediate Similarity	NPD3818	Discontinued
0.8061	Intermediate Similarity	NPD6232	Discontinued
0.8036	Intermediate Similarity	NPD7804	Clinical (unspecified phase)
0.8026	Intermediate Similarity	NPD1510	Phase 2
0.8024	Intermediate Similarity	NPD7473	Discontinued
0.8012	Intermediate Similarity	NPD1934	Approved
0.8	Intermediate Similarity	NPD1240	Approved
0.8	Intermediate Similarity	NPD3750	Approved
0.7988	Intermediate Similarity	NPD7074	Phase 3
0.7962	Intermediate Similarity	NPD1511	Approved
0.7929	Intermediate Similarity	NPD7054	Approved
0.7914	Intermediate Similarity	NPD8443	Clinical (unspecified phase)
0.7908	Intermediate Similarity	NPD2799	Discontinued
0.7908	Intermediate Similarity	NPD1509	Clinical (unspecified phase)
0.7898	Intermediate Similarity	NPD7879	Clinical (unspecified phase)
0.7888	Intermediate Similarity	NPD4380	Phase 2
0.7882	Intermediate Similarity	NPD7472	Approved
0.7866	Intermediate Similarity	NPD7768	Phase 2
0.7862	Intermediate Similarity	NPD1512	Approved
0.7857	Intermediate Similarity	NPD2935	Discontinued
0.7853	Intermediate Similarity	NPD2801	Approved
0.784	Intermediate Similarity	NPD7411	Suspended
0.7836	Intermediate Similarity	NPD6797	Phase 2
0.7824	Intermediate Similarity	NPD5844	Phase 1
0.7821	Intermediate Similarity	NPD2800	Approved
0.7818	Intermediate Similarity	NPD7075	Discontinued
0.7805	Intermediate Similarity	NPD5402	Approved
0.7799	Intermediate Similarity	NPD7410	Clinical (unspecified phase)
0.7791	Intermediate Similarity	NPD7251	Discontinued
0.7778	Intermediate Similarity	NPD6599	Discontinued
0.7758	Intermediate Similarity	NPD3882	Suspended
0.7748	Intermediate Similarity	NPD2313	Discontinued
0.7746	Intermediate Similarity	NPD7808	Phase 3
0.7746	Intermediate Similarity	NPD4338	Clinical (unspecified phase)
0.7744	Intermediate Similarity	NPD7096	Clinical (unspecified phase)
0.7742	Intermediate Similarity	NPD2796	Approved
0.7716	Intermediate Similarity	NPD5808	Clinical (unspecified phase)
0.7711	Intermediate Similarity	NPD3749	Approved
0.7702	Intermediate Similarity	NPD920	Approved
0.7683	Intermediate Similarity	NPD6801	Discontinued
0.7682	Intermediate Similarity	NPD4625	Phase 3
0.7677	Intermediate Similarity	NPD3748	Approved
0.7658	Intermediate Similarity	NPD6398	Clinical (unspecified phase)
0.7651	Intermediate Similarity	NPD1203	Approved
0.7651	Intermediate Similarity	NPD1470	Approved
0.7647	Intermediate Similarity	NPD6167	Clinical (unspecified phase)
0.7647	Intermediate Similarity	NPD6168	Clinical (unspecified phase)
0.7647	Intermediate Similarity	NPD7852	Clinical (unspecified phase)
0.7647	Intermediate Similarity	NPD6166	Phase 2
0.7633	Intermediate Similarity	NPD5711	Approved
0.7633	Intermediate Similarity	NPD5710	Approved
0.7628	Intermediate Similarity	NPD6099	Approved
0.7628	Intermediate Similarity	NPD6100	Approved
0.7625	Intermediate Similarity	NPD6799	Approved
0.7619	Intermediate Similarity	NPD1201	Approved
0.7619	Intermediate Similarity	NPD5494	Approved
0.7596	Intermediate Similarity	NPD6781	Approved
0.7596	Intermediate Similarity	NPD6776	Approved
0.7596	Intermediate Similarity	NPD6778	Approved
0.7596	Intermediate Similarity	NPD6777	Approved
0.7596	Intermediate Similarity	NPD6782	Approved
0.7596	Intermediate Similarity	NPD6779	Approved
0.7596	Intermediate Similarity	NPD6780	Approved
0.7593	Intermediate Similarity	NPD5403	Approved
0.759	Intermediate Similarity	NPD3817	Phase 2
0.7578	Intermediate Similarity	NPD642	Clinical (unspecified phase)
0.7578	Intermediate Similarity	NPD5401	Approved
0.7576	Intermediate Similarity	NPD37	Approved
0.7545	Intermediate Similarity	NPD4965	Approved
0.7545	Intermediate Similarity	NPD4966	Approved
0.7545	Intermediate Similarity	NPD4967	Phase 2
0.7516	Intermediate Similarity	NPD7390	Discontinued
0.7516	Intermediate Similarity	NPD411	Approved
0.7514	Intermediate Similarity	NPD6823	Phase 2
0.7484	Intermediate Similarity	NPD1243	Approved
0.7484	Intermediate Similarity	NPD447	Suspended
0.7484	Intermediate Similarity	NPD7421	Clinical (unspecified phase)
0.7484	Intermediate Similarity	NPD1899	Clinical (unspecified phase)
0.7483	Intermediate Similarity	NPD2798	Approved
0.7473	Intermediate Similarity	NPD7697	Approved
0.7473	Intermediate Similarity	NPD7435	Discontinued
0.7473	Intermediate Similarity	NPD7698	Approved
0.7473	Intermediate Similarity	NPD7696	Phase 3
0.7457	Intermediate Similarity	NPD3751	Discontinued
0.7456	Intermediate Similarity	NPD6234	Discontinued
0.7453	Intermediate Similarity	NPD643	Clinical (unspecified phase)
0.745	Intermediate Similarity	NPD9717	Approved
0.744	Intermediate Similarity	NPD4868	Clinical (unspecified phase)
0.7438	Intermediate Similarity	NPD4628	Phase 3
0.7433	Intermediate Similarity	NPD7870	Phase 2
0.7433	Intermediate Similarity	NPD7871	Phase 2
0.7429	Intermediate Similarity	NPD5953	Discontinued
0.7425	Intermediate Similarity	NPD1465	Phase 2
0.7414	Intermediate Similarity	NPD7286	Phase 2
0.7403	Intermediate Similarity	NPD1699	Clinical (unspecified phase)
0.7403	Intermediate Similarity	NPD6859	Clinical (unspecified phase)
0.7389	Intermediate Similarity	NPD8397	Clinical (unspecified phase)
0.7386	Intermediate Similarity	NPD6832	Phase 2
0.7383	Intermediate Similarity	NPD1547	Clinical (unspecified phase)
0.7368	Intermediate Similarity	NPD8151	Discontinued
0.7368	Intermediate Similarity	NPD1247	Approved
0.7362	Intermediate Similarity	NPD7004	Clinical (unspecified phase)
0.7358	Intermediate Similarity	NPD2343	Clinical (unspecified phase)
0.7358	Intermediate Similarity	NPD2344	Approved
0.7356	Intermediate Similarity	NPD7228	Approved
0.7353	Intermediate Similarity	NPD919	Approved
0.7351	Intermediate Similarity	NPD1283	Approved
0.7345	Intermediate Similarity	NPD4419	Clinical (unspecified phase)
0.7342	Intermediate Similarity	NPD4308	Phase 3
0.7333	Intermediate Similarity	NPD1608	Approved
0.7326	Intermediate Similarity	NPD3787	Discontinued
0.7322	Intermediate Similarity	NPD6534	Approved
0.7322	Intermediate Similarity	NPD6535	Approved
0.7316	Intermediate Similarity	NPD7701	Phase 2
0.7308	Intermediate Similarity	NPD943	Approved
0.7296	Intermediate Similarity	NPD5408	Approved
0.7296	Intermediate Similarity	NPD5404	Approved
0.7296	Intermediate Similarity	NPD5406	Approved
0.7296	Intermediate Similarity	NPD5405	Approved
0.7292	Intermediate Similarity	NPD7783	Phase 2
0.7292	Intermediate Similarity	NPD7782	Clinical (unspecified phase)
0.729	Intermediate Similarity	NPD6410	Clinical (unspecified phase)
0.729	Intermediate Similarity	NPD4907	Clinical (unspecified phase)
0.7267	Intermediate Similarity	NPD1610	Phase 2
0.7267	Intermediate Similarity	NPD7199	Phase 2
0.725	Intermediate Similarity	NPD1471	Phase 3
0.724	Intermediate Similarity	NPD7874	Approved
0.724	Intermediate Similarity	NPD7875	Clinical (unspecified phase)
0.7233	Intermediate Similarity	NPD651	Clinical (unspecified phase)
0.7232	Intermediate Similarity	NPD7993	Clinical (unspecified phase)
0.7225	Intermediate Similarity	NPD7229	Phase 3
0.7215	Intermediate Similarity	NPD6651	Approved
0.7204	Intermediate Similarity	NPD7699	Phase 2
0.7204	Intermediate Similarity	NPD7700	Phase 2
0.7202	Intermediate Similarity	NPD7801	Approved
0.7197	Intermediate Similarity	NPD1613	Approved
0.7197	Intermediate Similarity	NPD1612	Clinical (unspecified phase)
0.719	Intermediate Similarity	NPD2797	Approved
0.7188	Intermediate Similarity	NPD4476	Approved
0.7188	Intermediate Similarity	NPD4477	Approved
0.7186	Intermediate Similarity	NPD7458	Discontinued
0.7182	Intermediate Similarity	NPD8150	Discontinued
0.7181	Intermediate Similarity	NPD1651	Approved
0.7179	Intermediate Similarity	NPD3268	Approved
0.7178	Intermediate Similarity	NPD2309	Approved
0.7174	Intermediate Similarity	NPD6212	Phase 3
0.7174	Intermediate Similarity	NPD6214	Clinical (unspecified phase)
0.7174	Intermediate Similarity	NPD6213	Phase 3
0.7171	Intermediate Similarity	NPD4749	Approved
0.7161	Intermediate Similarity	NPD4908	Phase 1
0.7159	Intermediate Similarity	NPD7177	Discontinued
0.7152	Intermediate Similarity	NPD1281	Approved
0.7152	Intermediate Similarity	NPD230	Phase 1
0.7152	Intermediate Similarity	NPD1933	Approved
0.7152	Intermediate Similarity	NPD1611	Approved
0.7152	Intermediate Similarity	NPD422	Phase 1
0.7143	Intermediate Similarity	NPD1019	Discontinued
0.7143	Intermediate Similarity	NPD6917	Clinical (unspecified phase)
0.7133	Intermediate Similarity	NPD17	Approved
0.7125	Intermediate Similarity	NPD7033	Discontinued
0.7118	Intermediate Similarity	NPD8455	Phase 2
0.7117	Intermediate Similarity	NPD7003	Approved
0.7114	Intermediate Similarity	NPD1548	Phase 1
0.7108	Intermediate Similarity	NPD6273	Approved
0.7101	Intermediate Similarity	NPD7615	Clinical (unspecified phase)
0.7095	Intermediate Similarity	NPD405	Clinical (unspecified phase)
0.7095	Intermediate Similarity	NPD9493	Approved
0.7089	Intermediate Similarity	NPD2979	Phase 3
0.7089	Intermediate Similarity	NPD4307	Phase 2
0.7089	Intermediate Similarity	NPD4060	Phase 1
0.7086	Intermediate Similarity	NPD7184	Clinical (unspecified phase)
0.7086	Intermediate Similarity	NPD3926	Phase 2
0.7076	Intermediate Similarity	NPD4288	Approved
0.707	Intermediate Similarity	NPD3764	Approved
0.7068	Intermediate Similarity	NPD8319	Approved
0.7068	Intermediate Similarity	NPD8320	Phase 1
0.7066	Intermediate Similarity	NPD6980	Clinical (unspecified phase)
0.7059	Intermediate Similarity	NPD6844	Discontinued
0.7055	Intermediate Similarity	NPD5698	Clinical (unspecified phase)
0.7051	Intermediate Similarity	NPD1529	Clinical (unspecified phase)

Structure

External Identifiers

PubChem CID	10564084
ChEMBL	CHEMBL456735
ZINC

Physicochemical Properties

Molecular Weight:	272.07
ALogP:	-1.0246
MLogP:	2.56
XLogP:	1.308
# Rotatable Bonds:	4
Polar Surface Area:	86.99
# H-Bond Aceptor:	2
# H-Bond Donor:	3
# Rings:	3
# Heavy Atoms:	20

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