Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT111 | Cell Line | K562 | Homo sapiens | LC50 | = | 15000 | nM | 21827183 |
NPT1821 | Individual Protein | Sortase | Staphylococcus aureus | IC50 | > | 200000 | nM | 21827183 |
NPT1087 | Individual Protein | Isocitrate lyase | Candida albicans | IC50 | = | 75000 | nM | 21827183 |
NPT2890 | Protein Complex | Sodium/potassium-transporting ATPase | Homo sapiens | IC50 | = | 6000 | nM | 21827183 |
NPT16 | Organism | Staphylococcus aureus | Staphylococcus aureus | MIC | > | 100 | ug/ml | 21827183 |
NPT79 | Organism | Bacillus subtilis | Bacillus subtilis | MIC | > | 100 | ug/ml | 21827183 |
NPT729 | Organism | Micrococcus luteus | Micrococcus luteus | MIC | > | 100 | ug/ml | 21827183 |
NPT566 | Organism | Salmonella typhimurium | Salmonella enterica subsp. enterica serovar Typhimurium | MIC | > | 100 | ug/ml | 21827183 |
NPT766 | Organism | Proteus vulgaris | Proteus vulgaris | MIC | > | 100 | ug/ml | 21827183 |
NPT19 | Organism | Escherichia coli | Escherichia coli | MIC | > | 100 | ug/ml | 21827183 |
NPT87 | Organism | Aspergillus fumigatus | Aspergillus fumigatus | MIC | > | 100 | ug/ml | 21827183 |
NPT329 | Organism | Trichophyton rubrum | Trichophyton rubrum | MIC | > | 100 | ug/ml | 21827183 |
NPT330 | Organism | Trichophyton mentagrophytes | Trichophyton mentagrophytes | MIC | > | 100 | ug/ml | 21827183 |
NPT20 | Organism | Candida albicans | Candida albicans | MIC | > | 100 | ug/ml | 21827183 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC319030 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.8333 | Intermediate Similarity | NPC473058 |
0.8242 | Intermediate Similarity | NPC159876 |
0.8191 | Intermediate Similarity | NPC472989 |
0.7957 | Intermediate Similarity | NPC48463 |
0.7921 | Intermediate Similarity | NPC475634 |
0.7895 | Intermediate Similarity | NPC275310 |
0.7895 | Intermediate Similarity | NPC230347 |
0.7895 | Intermediate Similarity | NPC286612 |
0.7879 | Intermediate Similarity | NPC213190 |
0.7857 | Intermediate Similarity | NPC4831 |
0.7857 | Intermediate Similarity | NPC129372 |
0.7857 | Intermediate Similarity | NPC309425 |
0.7857 | Intermediate Similarity | NPC47566 |
0.7857 | Intermediate Similarity | NPC88000 |
0.7857 | Intermediate Similarity | NPC160734 |
0.7857 | Intermediate Similarity | NPC472023 |
0.7843 | Intermediate Similarity | NPC474573 |
0.7835 | Intermediate Similarity | NPC5358 |
0.7835 | Intermediate Similarity | NPC216260 |
0.7812 | Intermediate Similarity | NPC90583 |
0.7778 | Intermediate Similarity | NPC166279 |
0.7778 | Intermediate Similarity | NPC319238 |
0.7778 | Intermediate Similarity | NPC136816 |
0.7766 | Intermediate Similarity | NPC302584 |
0.7755 | Intermediate Similarity | NPC7341 |
0.7755 | Intermediate Similarity | NPC473200 |
0.7732 | Intermediate Similarity | NPC76486 |
0.77 | Intermediate Similarity | NPC31907 |
0.77 | Intermediate Similarity | NPC286969 |
0.77 | Intermediate Similarity | NPC131479 |
0.77 | Intermediate Similarity | NPC211879 |
0.77 | Intermediate Similarity | NPC8039 |
0.77 | Intermediate Similarity | NPC114874 |
0.77 | Intermediate Similarity | NPC472252 |
0.77 | Intermediate Similarity | NPC120123 |
0.77 | Intermediate Similarity | NPC189852 |
0.77 | Intermediate Similarity | NPC16520 |
0.77 | Intermediate Similarity | NPC245280 |
0.77 | Intermediate Similarity | NPC155010 |
0.77 | Intermediate Similarity | NPC473020 |
0.77 | Intermediate Similarity | NPC157659 |
0.7684 | Intermediate Similarity | NPC474835 |
0.7684 | Intermediate Similarity | NPC474792 |
0.7684 | Intermediate Similarity | NPC67398 |
0.7684 | Intermediate Similarity | NPC91654 |
0.7677 | Intermediate Similarity | NPC31346 |
0.766 | Intermediate Similarity | NPC261990 |
0.766 | Intermediate Similarity | NPC474249 |
0.7653 | Intermediate Similarity | NPC280825 |
0.7653 | Intermediate Similarity | NPC157739 |
0.7653 | Intermediate Similarity | NPC234287 |
0.7629 | Intermediate Similarity | NPC207617 |
0.7624 | Intermediate Similarity | NPC273879 |
0.7624 | Intermediate Similarity | NPC165033 |
0.7624 | Intermediate Similarity | NPC476361 |
0.7624 | Intermediate Similarity | NPC476360 |
0.7624 | Intermediate Similarity | NPC475521 |
0.7604 | Intermediate Similarity | NPC72817 |
0.7604 | Intermediate Similarity | NPC211238 |
0.7604 | Intermediate Similarity | NPC477927 |
0.7604 | Intermediate Similarity | NPC305160 |
0.76 | Intermediate Similarity | NPC159036 |
0.76 | Intermediate Similarity | NPC288694 |
0.76 | Intermediate Similarity | NPC94919 |
0.76 | Intermediate Similarity | NPC312553 |
0.7579 | Intermediate Similarity | NPC120539 |
0.7579 | Intermediate Similarity | NPC289361 |
0.7576 | Intermediate Similarity | NPC471247 |
0.7576 | Intermediate Similarity | NPC91497 |
0.7576 | Intermediate Similarity | NPC324598 |
0.7576 | Intermediate Similarity | NPC282669 |
0.7573 | Intermediate Similarity | NPC220427 |
0.7573 | Intermediate Similarity | NPC224414 |
0.7556 | Intermediate Similarity | NPC477599 |
0.7551 | Intermediate Similarity | NPC473555 |
0.7551 | Intermediate Similarity | NPC473890 |
0.7551 | Intermediate Similarity | NPC278939 |
0.7551 | Intermediate Similarity | NPC243728 |
0.7551 | Intermediate Similarity | NPC471770 |
0.7549 | Intermediate Similarity | NPC472900 |
0.7549 | Intermediate Similarity | NPC194842 |
0.7549 | Intermediate Similarity | NPC472899 |
0.7549 | Intermediate Similarity | NPC473199 |
0.7549 | Intermediate Similarity | NPC69737 |
0.7549 | Intermediate Similarity | NPC160816 |
0.7549 | Intermediate Similarity | NPC208477 |
0.7549 | Intermediate Similarity | NPC208594 |
0.7549 | Intermediate Similarity | NPC152584 |
0.7549 | Intermediate Similarity | NPC269627 |
0.7549 | Intermediate Similarity | NPC127801 |
0.7549 | Intermediate Similarity | NPC472898 |
0.7549 | Intermediate Similarity | NPC26798 |
0.7547 | Intermediate Similarity | NPC476671 |
0.7527 | Intermediate Similarity | NPC477600 |
0.7525 | Intermediate Similarity | NPC473198 |
0.7525 | Intermediate Similarity | NPC16573 |
0.75 | Intermediate Similarity | NPC246860 |
0.75 | Intermediate Similarity | NPC177343 |
0.75 | Intermediate Similarity | NPC117714 |
0.75 | Intermediate Similarity | NPC263756 |
0.7476 | Intermediate Similarity | NPC63368 |
0.7476 | Intermediate Similarity | NPC54619 |
0.7476 | Intermediate Similarity | NPC231340 |
0.7476 | Intermediate Similarity | NPC226642 |
0.7476 | Intermediate Similarity | NPC208650 |
0.7476 | Intermediate Similarity | NPC181467 |
0.7476 | Intermediate Similarity | NPC14946 |
0.7475 | Intermediate Similarity | NPC309493 |
0.7475 | Intermediate Similarity | NPC158088 |
0.7473 | Intermediate Similarity | NPC324243 |
0.7471 | Intermediate Similarity | NPC470766 |
0.7453 | Intermediate Similarity | NPC475354 |
0.7453 | Intermediate Similarity | NPC475312 |
0.7451 | Intermediate Similarity | NPC470043 |
0.7451 | Intermediate Similarity | NPC187400 |
0.7451 | Intermediate Similarity | NPC470057 |
0.7451 | Intermediate Similarity | NPC470062 |
0.7451 | Intermediate Similarity | NPC470064 |
0.7451 | Intermediate Similarity | NPC470061 |
0.7451 | Intermediate Similarity | NPC470059 |
0.7451 | Intermediate Similarity | NPC121566 |
0.7451 | Intermediate Similarity | NPC470060 |
0.7451 | Intermediate Similarity | NPC470058 |
0.7451 | Intermediate Similarity | NPC31430 |
0.7451 | Intermediate Similarity | NPC221562 |
0.7451 | Intermediate Similarity | NPC470885 |
0.7451 | Intermediate Similarity | NPC475365 |
0.7451 | Intermediate Similarity | NPC100955 |
0.7451 | Intermediate Similarity | NPC85593 |
0.7447 | Intermediate Similarity | NPC473436 |
0.7447 | Intermediate Similarity | NPC263079 |
0.7431 | Intermediate Similarity | NPC476691 |
0.7431 | Intermediate Similarity | NPC476692 |
0.7429 | Intermediate Similarity | NPC106760 |
0.7426 | Intermediate Similarity | NPC256133 |
0.7426 | Intermediate Similarity | NPC30289 |
0.7426 | Intermediate Similarity | NPC76497 |
0.7426 | Intermediate Similarity | NPC213674 |
0.7426 | Intermediate Similarity | NPC272015 |
0.7423 | Intermediate Similarity | NPC473503 |
0.7419 | Intermediate Similarity | NPC173917 |
0.7404 | Intermediate Similarity | NPC159005 |
0.7404 | Intermediate Similarity | NPC38376 |
0.7404 | Intermediate Similarity | NPC80210 |
0.7404 | Intermediate Similarity | NPC49032 |
0.7404 | Intermediate Similarity | NPC180183 |
0.7404 | Intermediate Similarity | NPC51172 |
0.7404 | Intermediate Similarity | NPC6931 |
0.7404 | Intermediate Similarity | NPC38217 |
0.7404 | Intermediate Similarity | NPC125324 |
0.7404 | Intermediate Similarity | NPC472988 |
0.7404 | Intermediate Similarity | NPC246124 |
0.74 | Intermediate Similarity | NPC473790 |
0.74 | Intermediate Similarity | NPC469942 |
0.74 | Intermediate Similarity | NPC317019 |
0.7396 | Intermediate Similarity | NPC473637 |
0.7396 | Intermediate Similarity | NPC476668 |
0.7379 | Intermediate Similarity | NPC165405 |
0.7379 | Intermediate Similarity | NPC474569 |
0.7379 | Intermediate Similarity | NPC181845 |
0.7379 | Intermediate Similarity | NPC95243 |
0.7379 | Intermediate Similarity | NPC63023 |
0.7379 | Intermediate Similarity | NPC309448 |
0.7374 | Intermediate Similarity | NPC125551 |
0.7374 | Intermediate Similarity | NPC309503 |
0.7374 | Intermediate Similarity | NPC91197 |
0.7374 | Intermediate Similarity | NPC96597 |
0.7374 | Intermediate Similarity | NPC239547 |
0.7374 | Intermediate Similarity | NPC155319 |
0.7374 | Intermediate Similarity | NPC240372 |
0.7368 | Intermediate Similarity | NPC82955 |
0.7358 | Intermediate Similarity | NPC272242 |
0.7353 | Intermediate Similarity | NPC473123 |
0.7353 | Intermediate Similarity | NPC473124 |
0.7353 | Intermediate Similarity | NPC162354 |
0.7353 | Intermediate Similarity | NPC473129 |
0.7353 | Intermediate Similarity | NPC123796 |
0.7353 | Intermediate Similarity | NPC99627 |
0.7347 | Intermediate Similarity | NPC469710 |
0.734 | Intermediate Similarity | NPC43912 |
0.734 | Intermediate Similarity | NPC140446 |
0.7333 | Intermediate Similarity | NPC151134 |
0.7333 | Intermediate Similarity | NPC40440 |
0.7333 | Intermediate Similarity | NPC285253 |
0.7333 | Intermediate Similarity | NPC296761 |
0.7333 | Intermediate Similarity | NPC154085 |
0.7333 | Intermediate Similarity | NPC472901 |
0.7333 | Intermediate Similarity | NPC51925 |
0.7333 | Intermediate Similarity | NPC195116 |
0.7333 | Intermediate Similarity | NPC43976 |
0.7333 | Intermediate Similarity | NPC221110 |
0.7333 | Intermediate Similarity | NPC180459 |
0.7333 | Intermediate Similarity | NPC8431 |
0.7333 | Intermediate Similarity | NPC125361 |
0.7333 | Intermediate Similarity | NPC42482 |
0.7327 | Intermediate Similarity | NPC121072 |
0.7327 | Intermediate Similarity | NPC285231 |
0.7327 | Intermediate Similarity | NPC21064 |
0.7327 | Intermediate Similarity | NPC21568 |
0.7327 | Intermediate Similarity | NPC470168 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC319030 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.7064 | Intermediate Similarity | NPD8133 | Approved |
0.6981 | Remote Similarity | NPD6412 | Phase 2 |
0.697 | Remote Similarity | NPD8171 | Discontinued |
0.6957 | Remote Similarity | NPD7525 | Registered |
0.6916 | Remote Similarity | NPD6686 | Approved |
0.6814 | Remote Similarity | NPD7328 | Approved |
0.6814 | Remote Similarity | NPD7327 | Approved |
0.6754 | Remote Similarity | NPD7516 | Approved |
0.6696 | Remote Similarity | NPD8377 | Approved |
0.6696 | Remote Similarity | NPD8294 | Approved |
0.6667 | Remote Similarity | NPD7645 | Phase 2 |
0.6638 | Remote Similarity | NPD8378 | Approved |
0.6638 | Remote Similarity | NPD8033 | Approved |
0.6638 | Remote Similarity | NPD8296 | Approved |
0.6638 | Remote Similarity | NPD7503 | Approved |
0.6638 | Remote Similarity | NPD8335 | Approved |
0.6638 | Remote Similarity | NPD8380 | Approved |
0.6638 | Remote Similarity | NPD8379 | Approved |
0.6633 | Remote Similarity | NPD7524 | Approved |
0.6627 | Remote Similarity | NPD1145 | Discontinued |
0.6591 | Remote Similarity | NPD4267 | Clinical (unspecified phase) |
0.6545 | Remote Similarity | NPD8132 | Clinical (unspecified phase) |
0.6522 | Remote Similarity | NPD6933 | Approved |
0.6495 | Remote Similarity | NPD7338 | Clinical (unspecified phase) |
0.6421 | Remote Similarity | NPD6928 | Phase 2 |
0.6417 | Remote Similarity | NPD7507 | Approved |
0.6413 | Remote Similarity | NPD6942 | Approved |
0.6413 | Remote Similarity | NPD7339 | Approved |
0.6392 | Remote Similarity | NPD6695 | Phase 3 |
0.6392 | Remote Similarity | NPD4788 | Approved |
0.6373 | Remote Similarity | NPD8034 | Phase 2 |
0.6373 | Remote Similarity | NPD8035 | Phase 2 |
0.6344 | Remote Similarity | NPD3701 | Clinical (unspecified phase) |
0.633 | Remote Similarity | NPD8170 | Clinical (unspecified phase) |
0.6304 | Remote Similarity | NPD1811 | Approved |
0.6304 | Remote Similarity | NPD6926 | Approved |
0.6304 | Remote Similarity | NPD6924 | Approved |
0.6304 | Remote Similarity | NPD1810 | Approved |
0.6303 | Remote Similarity | NPD6370 | Approved |
0.6293 | Remote Similarity | NPD8295 | Clinical (unspecified phase) |
0.6263 | Remote Similarity | NPD7520 | Clinical (unspecified phase) |
0.626 | Remote Similarity | NPD7319 | Approved |
0.625 | Remote Similarity | NPD8328 | Phase 3 |
0.6228 | Remote Similarity | NPD6882 | Approved |
0.6179 | Remote Similarity | NPD7736 | Approved |
0.6168 | Remote Similarity | NPD4225 | Approved |
0.6154 | Remote Similarity | NPD6399 | Phase 3 |
0.6139 | Remote Similarity | NPD7750 | Discontinued |
0.6134 | Remote Similarity | NPD6059 | Approved |
0.6134 | Remote Similarity | NPD6054 | Approved |
0.6116 | Remote Similarity | NPD6067 | Discontinued |
0.6098 | Remote Similarity | NPD8293 | Discontinued |
0.6087 | Remote Similarity | NPD8297 | Approved |
0.6087 | Remote Similarity | NPD4243 | Approved |
0.6082 | Remote Similarity | NPD7509 | Discontinued |
0.6082 | Remote Similarity | NPD6931 | Approved |
0.6082 | Remote Similarity | NPD6930 | Phase 2 |
0.6075 | Remote Similarity | NPD6084 | Phase 2 |
0.6075 | Remote Similarity | NPD6083 | Phase 2 |
0.6019 | Remote Similarity | NPD7638 | Approved |
0.6 | Remote Similarity | NPD3668 | Phase 3 |
0.6 | Remote Similarity | NPD4786 | Approved |
0.5984 | Remote Similarity | NPD8449 | Approved |
0.5982 | Remote Similarity | NPD6675 | Approved |
0.5982 | Remote Similarity | NPD5739 | Approved |
0.5982 | Remote Similarity | NPD7128 | Approved |
0.5982 | Remote Similarity | NPD6402 | Approved |
0.5979 | Remote Similarity | NPD6929 | Approved |
0.5978 | Remote Similarity | NPD2686 | Approved |
0.5978 | Remote Similarity | NPD2254 | Approved |
0.5978 | Remote Similarity | NPD2687 | Approved |
0.5965 | Remote Similarity | NPD6373 | Approved |
0.5965 | Remote Similarity | NPD6372 | Approved |
0.5963 | Remote Similarity | NPD7640 | Approved |
0.5963 | Remote Similarity | NPD7639 | Approved |
0.596 | Remote Similarity | NPD3667 | Approved |
0.5957 | Remote Similarity | NPD4785 | Approved |
0.5957 | Remote Similarity | NPD4784 | Approved |
0.595 | Remote Similarity | NPD6015 | Approved |
0.595 | Remote Similarity | NPD6016 | Approved |
0.5943 | Remote Similarity | NPD7748 | Approved |
0.5938 | Remote Similarity | NPD6932 | Approved |
0.5938 | Remote Similarity | NPD8450 | Suspended |
0.5935 | Remote Similarity | NPD7492 | Approved |
0.5926 | Remote Similarity | NPD7902 | Approved |
0.5909 | Remote Similarity | NPD4159 | Approved |
0.5905 | Remote Similarity | NPD7087 | Discontinued |
0.5905 | Remote Similarity | NPD7515 | Phase 2 |
0.5902 | Remote Similarity | NPD5988 | Approved |
0.59 | Remote Similarity | NPD3670 | Clinical (unspecified phase) |
0.59 | Remote Similarity | NPD3669 | Approved |
0.5887 | Remote Similarity | NPD6616 | Approved |
0.5877 | Remote Similarity | NPD5345 | Clinical (unspecified phase) |
0.5877 | Remote Similarity | NPD6899 | Approved |
0.5877 | Remote Similarity | NPD7320 | Approved |
0.5877 | Remote Similarity | NPD6881 | Approved |
0.587 | Remote Similarity | NPD6922 | Approved |
0.587 | Remote Similarity | NPD6923 | Approved |
0.5865 | Remote Similarity | NPD4753 | Phase 2 |
0.5865 | Remote Similarity | NPD6051 | Approved |
0.5862 | Remote Similarity | NPD6650 | Approved |
0.5862 | Remote Similarity | NPD6649 | Approved |
0.5842 | Remote Similarity | NPD6400 | Clinical (unspecified phase) |
0.5842 | Remote Similarity | NPD3666 | Approved |
0.5842 | Remote Similarity | NPD3133 | Approved |
0.5842 | Remote Similarity | NPD3665 | Phase 1 |
0.584 | Remote Similarity | NPD7078 | Approved |
0.5826 | Remote Similarity | NPD4061 | Clinical (unspecified phase) |
0.5825 | Remote Similarity | NPD4751 | Clinical (unspecified phase) |
0.5816 | Remote Similarity | NPD6683 | Phase 2 |
0.5806 | Remote Similarity | NPD7532 | Clinical (unspecified phase) |
0.5806 | Remote Similarity | NPD7144 | Approved |
0.5806 | Remote Similarity | NPD4787 | Phase 1 |
0.5806 | Remote Similarity | NPD7143 | Approved |
0.5789 | Remote Similarity | NPD5701 | Approved |
0.5789 | Remote Similarity | NPD5697 | Approved |
0.5784 | Remote Similarity | NPD6893 | Approved |
0.578 | Remote Similarity | NPD4755 | Approved |
0.5776 | Remote Similarity | NPD7102 | Approved |
0.5776 | Remote Similarity | NPD7290 | Approved |
0.5776 | Remote Similarity | NPD6883 | Approved |
0.5773 | Remote Similarity | NPD5776 | Phase 2 |
0.5773 | Remote Similarity | NPD6116 | Phase 1 |
0.5773 | Remote Similarity | NPD6925 | Approved |
0.5769 | Remote Similarity | NPD7513 | Clinical (unspecified phase) |
0.5758 | Remote Similarity | NPD7332 | Phase 2 |
0.5758 | Remote Similarity | NPD7514 | Phase 3 |
0.5758 | Remote Similarity | NPD4748 | Discontinued |
0.575 | Remote Similarity | NPD6009 | Approved |
0.575 | Remote Similarity | NPD7115 | Discovery |
0.5745 | Remote Similarity | NPD7151 | Approved |
0.5745 | Remote Similarity | NPD7150 | Approved |
0.5745 | Remote Similarity | NPD7152 | Approved |
0.5741 | Remote Similarity | NPD5695 | Phase 3 |
0.5738 | Remote Similarity | NPD6319 | Approved |
0.5729 | Remote Similarity | NPD4190 | Phase 3 |
0.5729 | Remote Similarity | NPD5275 | Approved |
0.5728 | Remote Similarity | NPD7334 | Approved |
0.5728 | Remote Similarity | NPD6684 | Approved |
0.5728 | Remote Similarity | NPD5330 | Approved |
0.5728 | Remote Similarity | NPD6409 | Approved |
0.5728 | Remote Similarity | NPD7146 | Approved |
0.5728 | Remote Similarity | NPD3618 | Phase 1 |
0.5728 | Remote Similarity | NPD7521 | Approved |
0.5727 | Remote Similarity | NPD5696 | Approved |
0.5726 | Remote Similarity | NPD6617 | Approved |
0.5726 | Remote Similarity | NPD6401 | Clinical (unspecified phase) |
0.5726 | Remote Similarity | NPD8130 | Phase 1 |
0.5726 | Remote Similarity | NPD6869 | Approved |
0.5726 | Remote Similarity | NPD8413 | Clinical (unspecified phase) |
0.5726 | Remote Similarity | NPD6847 | Approved |
0.5714 | Remote Similarity | NPD5328 | Approved |
0.5714 | Remote Similarity | NPD7322 | Clinical (unspecified phase) |
0.5714 | Remote Similarity | NPD7145 | Approved |
0.5701 | Remote Similarity | NPD4202 | Approved |
0.57 | Remote Similarity | NPD6898 | Phase 1 |
0.5691 | Remote Similarity | NPD8516 | Approved |
0.5691 | Remote Similarity | NPD8517 | Approved |
0.5691 | Remote Similarity | NPD8515 | Approved |
0.5691 | Remote Similarity | NPD8513 | Phase 3 |
0.569 | Remote Similarity | NPD6014 | Approved |
0.569 | Remote Similarity | NPD6013 | Approved |
0.569 | Remote Similarity | NPD6012 | Approved |
0.5676 | Remote Similarity | NPD5285 | Approved |
0.5676 | Remote Similarity | NPD4700 | Approved |
0.5676 | Remote Similarity | NPD5286 | Approved |
0.5676 | Remote Similarity | NPD4696 | Approved |
0.567 | Remote Similarity | NPD6117 | Approved |
0.5669 | Remote Similarity | NPD6033 | Approved |
0.5667 | Remote Similarity | NPD371 | Approved |
0.566 | Remote Similarity | NPD3168 | Discontinued |
0.5657 | Remote Similarity | NPD4195 | Approved |
0.5648 | Remote Similarity | NPD7900 | Approved |
0.5648 | Remote Similarity | NPD7901 | Clinical (unspecified phase) |
0.5641 | Remote Similarity | NPD5955 | Clinical (unspecified phase) |
0.5638 | Remote Similarity | NPD4244 | Approved |
0.5638 | Remote Similarity | NPD4245 | Approved |
0.563 | Remote Similarity | NPD4632 | Approved |
0.5625 | Remote Similarity | NPD6113 | Clinical (unspecified phase) |
0.5619 | Remote Similarity | NPD6903 | Approved |
0.5619 | Remote Similarity | NPD6672 | Approved |
0.5619 | Remote Similarity | NPD5737 | Approved |
0.5607 | Remote Similarity | NPD6079 | Approved |
0.5607 | Remote Similarity | NPD7637 | Suspended |
0.5607 | Remote Similarity | NPD6411 | Approved |
0.5603 | Remote Similarity | NPD8174 | Phase 2 |
0.5603 | Remote Similarity | NPD6011 | Approved |
PubChem CID   | 53484121 |
ChEMBL   | CHEMBL1818094 |
ZINC   |
Molecular Weight:   | 545.28 |
ALogP:   | -0.635 |
MLogP:   | 3.33 |
XLogP:   | 5.165 |
# Rotatable Bonds:   | 16 |
Polar Surface Area:   | 142.96 |
# H-Bond Aceptor:   | 9 |
# H-Bond Donor:   | 2 |
# Rings:   | 4 |
# Heavy Atoms:   | 37 |