Target ID |
Target Type |
Target Name |
Target Organism |
Activity Type |
Activity Relation |
Value |
Unit |
Reference |
NPT1567 |
Protein Complex |
DNA gyrase |
Escherichia coli K-12 |
IC50 |
= |
0.25 |
ug/ml |
15125947 |
NPT317 |
Uncleic Acid |
Nucleic Acid |
|
IC50 |
= |
25 |
ug/ml |
15125947 |
NPT320 |
Protein Family |
DNA topoisomerase II |
Homo sapiens |
IC50 |
> |
400 |
ug/ml |
15125947 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
15125947 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC |
= |
2 |
ug/ml |
15125947 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
1 |
|
10673102 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
< |
0.04 |
ug/ml |
10673102 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
10 |
ug/ml |
10673102 |
NPT17 |
Organism |
Staphylococcus epidermidis |
Staphylococcus epidermidis |
MIC |
< |
0.04 |
ug/ml |
10673102 |
NPT1228 |
Organism |
Streptococcus pyogenes |
Streptococcus pyogenes |
MIC |
= |
0.3 |
ug/ml |
10673102 |
NPT1531 |
Organism |
Enterococcus faecium |
Enterococcus faecium |
MIC |
= |
0.6 |
ug/ml |
10673102 |
NPT322 |
Individual Protein |
DNA topoisomerase II beta |
Homo sapiens |
Ratio |
= |
1 |
|
10522710 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
< |
0.04 |
ug/ml |
10522710 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
20 |
ug/ml |
10522710 |
NPT17 |
Organism |
Staphylococcus epidermidis |
Staphylococcus epidermidis |
MIC |
= |
0.08 |
ug/ml |
10522710 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.15 |
ug/ml |
10522710 |
NPT1531 |
Organism |
Enterococcus faecium |
Enterococcus faecium |
MIC |
= |
0.3 |
ug/ml |
10522710 |
NPT1567 |
Protein Complex |
DNA gyrase |
Escherichia coli K-12 |
IC50 |
= |
0.25 |
ug/ml |
11378377 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
< |
0.04 |
ug/ml |
11378377 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
2.5 |
ug/ml |
11378377 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
> |
64 |
ug/ml |
14998336 |
NPT1521 |
Organism |
Stenotrophomonas maltophilia |
Stenotrophomonas maltophilia |
MIC |
> |
64 |
ug/ml |
14998336 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
14998336 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.12 |
ug/ml |
14998336 |
NPT17 |
Organism |
Staphylococcus epidermidis |
Staphylococcus epidermidis |
MIC |
= |
0.25 |
ug/ml |
14998336 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC |
= |
4 |
ug/ml |
14998336 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
1 |
ug/ml |
14998336 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
ED50 |
= |
3 |
mg/kg |
14998336 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC50 |
= |
4 |
ug/ml |
14998336 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC90 |
= |
8 |
ug/ml |
14998336 |
NPT1567 |
Protein Complex |
DNA gyrase |
Escherichia coli K-12 |
Ratio |
= |
1 |
|
10450985 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
< |
0.04 |
ug/ml |
10450985 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
20 |
ug/ml |
10450985 |
NPT17 |
Organism |
Staphylococcus epidermidis |
Staphylococcus epidermidis |
MIC |
= |
0.08 |
ug/ml |
10450985 |
NPT1228 |
Organism |
Streptococcus pyogenes |
Streptococcus pyogenes |
MIC |
= |
0.15 |
ug/ml |
10450985 |
NPT1531 |
Organism |
Enterococcus faecium |
Enterococcus faecium |
MIC |
= |
0.3 |
ug/ml |
10450985 |
NPT4940 |
Individual Protein |
DNA gyrase subunit B |
Escherichia coli K-12 |
Ratio |
= |
1 |
|
10522711 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
< |
0.04 |
ug/ml |
10522711 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
20 |
ug/ml |
10522711 |
NPT17 |
Organism |
Staphylococcus epidermidis |
Staphylococcus epidermidis |
MIC |
= |
0.08 |
ug/ml |
10522711 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.15 |
ug/ml |
10522711 |
NPT1531 |
Organism |
Enterococcus faecium |
Enterococcus faecium |
MIC |
= |
0.3 |
ug/ml |
10522711 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
1 |
|
10937727 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
< |
0.04 |
ug/ml |
10937727 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
10 |
ug/ml |
10937727 |
NPT17 |
Organism |
Staphylococcus epidermidis |
Staphylococcus epidermidis |
MIC |
< |
0.04 |
ug/ml |
10937727 |
NPT1228 |
Organism |
Streptococcus pyogenes |
Streptococcus pyogenes |
MIC |
= |
0.3 |
ug/ml |
10937727 |
NPT1531 |
Organism |
Enterococcus faecium |
Enterococcus faecium |
MIC |
= |
0.6 |
ug/ml |
10937727 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
15214796 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
64 |
ug/ml |
15214796 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
0.5 |
ug/ml |
15214796 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.125 |
ug/ml |
15214796 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
4 |
ug/ml |
15214796 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
0.5 |
ug/ml |
15214796 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC |
= |
2 |
ug/ml |
15214796 |
NPT317 |
Uncleic Acid |
Nucleic Acid |
|
IC50 |
= |
0.25 |
ug/ml |
15214796 |
NPT317 |
Uncleic Acid |
Nucleic Acid |
|
IC50 |
= |
28 |
ug/ml |
15214796 |
NPT1567 |
Protein Complex |
DNA gyrase |
Escherichia coli K-12 |
IC50 |
= |
0.25 |
ug/ml |
15214796 |
NPT317 |
Uncleic Acid |
Nucleic Acid |
|
IC50 |
= |
3.5 |
ug/ml |
15214796 |
NPT317 |
Uncleic Acid |
Nucleic Acid |
|
IC50 |
> |
400 |
ug/ml |
15214796 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
10782694 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
8 |
ug/ml |
10782694 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
16 |
ug/ml |
10782694 |
NPT17 |
Organism |
Staphylococcus epidermidis |
Staphylococcus epidermidis |
MIC |
= |
0.12 |
ug/ml |
10782694 |
NPT1228 |
Organism |
Streptococcus pyogenes |
Streptococcus pyogenes |
MIC |
= |
2 |
ug/ml |
10782694 |
NPT1531 |
Organism |
Enterococcus faecium |
Enterococcus faecium |
MIC |
= |
8 |
ug/ml |
10782694 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
125 |
ug/ml |
10956216 |
NPT173 |
Organism |
Klebsiella pneumoniae |
Klebsiella pneumoniae |
MIC |
= |
250 |
ug/ml |
10956216 |
NPT173 |
Organism |
Klebsiella pneumoniae |
Klebsiella pneumoniae |
MIC |
= |
62 |
ug/ml |
10956216 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
80 |
% |
15582408 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
20 |
% |
15582408 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
10 |
% |
15582408 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
IZ |
= |
9 |
mm |
17149863 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
IZ |
= |
15 |
mm |
17149863 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.13 |
ug/ml |
17116675 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
17116675 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
1 |
ug/ml |
17116675 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
8 |
ug/ml |
17116675 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
2 |
ug/ml |
17116675 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
0.5 |
ug/ml |
17116675 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
8 |
ug/ml |
17116675 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
4 |
ug/ml |
17116675 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC |
= |
8 |
ug/ml |
17116675 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC |
= |
16 |
ug/ml |
17116675 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC |
= |
32 |
ug/ml |
17116675 |
NPT1122 |
Organism |
Haemophilus influenzae |
Haemophilus influenzae |
MIC |
= |
0.064 |
ug/ml |
17116675 |
NPT1122 |
Organism |
Haemophilus influenzae |
Haemophilus influenzae |
MIC |
= |
8 |
ug/ml |
17116675 |
NPT1122 |
Organism |
Haemophilus influenzae |
Haemophilus influenzae |
MIC |
= |
4 |
ug/ml |
17116675 |
NPT1122 |
Organism |
Haemophilus influenzae |
Haemophilus influenzae |
MIC |
= |
0.25 |
ug/ml |
17116675 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.5 |
ug/ml |
17116675 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
512 |
ug/ml |
17210767 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
4 |
ug/ml |
17210767 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
IC50 |
= |
260000 |
nM |
17979263 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
Activity |
= |
5.9 |
% |
17979263 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
Activity |
= |
59.9 |
% |
17979263 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
Activity |
= |
19.7 |
% |
17979263 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
Activity |
= |
19.3 |
% |
17979263 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
Activity |
= |
9.8 |
% |
17979263 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
Activity |
= |
58.3 |
% |
17979263 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
Activity |
= |
21.3 |
% |
17979263 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
> |
0.125 |
ug/ml |
17561394 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.5 |
ug/ml |
17561394 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
1 |
ug/ml |
17561394 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
0.25 |
ug/ml |
17632001 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
17632001 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
8 |
ug/ml |
17632001 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.12 |
ug/ml |
17632001 |
NPT17 |
Organism |
Staphylococcus epidermidis |
Staphylococcus epidermidis |
MIC |
= |
0.12 |
ug/ml |
17632001 |
NPT1228 |
Organism |
Streptococcus pyogenes |
Streptococcus pyogenes |
MIC |
= |
2 |
ug/ml |
17632001 |
NPT1531 |
Organism |
Enterococcus faecium |
Enterococcus faecium |
MIC |
= |
8 |
ug/ml |
17632001 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
500000 |
nM |
18020309 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
> |
1024 |
ug/ml |
17438056 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
512 |
ug/ml |
17438056 |
NPT566 |
Organism |
Salmonella typhimurium |
Salmonella enterica subsp. enterica serovar Typhimurium |
MIC |
> |
1024 |
ug/ml |
17438056 |
NPT79 |
Organism |
Bacillus subtilis |
Bacillus subtilis |
MIC |
= |
0.78 |
ug/ml |
18262793 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
3.125 |
ug/ml |
18262793 |
NPT1209 |
Organism |
Pseudomonas fluorescens |
Pseudomonas fluorescens |
MIC |
= |
1.562 |
ug/ml |
18262793 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
3.125 |
ug/ml |
18262793 |
NPT5484 |
Protein Complex |
DNA gyrase |
Staphylococcus aureus |
IC50 |
= |
0.28 |
ug/ml |
18262793 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
0.31 |
ug/ml |
18262793 |
NPT1422 |
Individual Protein |
ATP-binding cassette sub-family G member 2 |
Homo sapiens |
IC50 |
= |
66069.34 |
nM |
18678495 |
NPT5484 |
Protein Complex |
DNA gyrase |
Staphylococcus aureus |
Ki |
= |
10 |
nM |
18690678 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
14 |
nM |
18690678 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
110 |
nM |
18690678 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.125 |
ug/ml |
18690678 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
> |
16 |
ug/ml |
18690678 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
2 |
ug/ml |
18690678 |
NPT1122 |
Organism |
Haemophilus influenzae |
Haemophilus influenzae |
MIC |
= |
0.063 |
ug/ml |
18690678 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
30 |
nM |
19095445 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.125 |
ug/ml |
19095445 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
1320 |
nM |
19095445 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC |
= |
8 |
ug/ml |
19095445 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
8 |
ug/ml |
19095445 |
NPT79 |
Organism |
Bacillus subtilis |
Bacillus subtilis |
MIC |
= |
0.78 |
ug/ml |
19147367 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
3.125 |
ug/ml |
19147367 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
1.562 |
ug/ml |
19147367 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
3.125 |
ug/ml |
19147367 |
NPT5484 |
Protein Complex |
DNA gyrase |
Staphylococcus aureus |
IC50 |
= |
0.25 |
ug/ml |
19147367 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
0.5 |
ug/ml |
19147367 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
2 |
|
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
28.6 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
36.5 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
17 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
25.3 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
36 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
25.5 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
32.6 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
25.7 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
9.5 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
20 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
24.5 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
21.3 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
38.4 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
50.9 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
28.4 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
45.3 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
55.2 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
48.5 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
39.8 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
46.8 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
23.6 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
21.2 |
% |
17606680 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Activity |
= |
26.9 |
% |
17606680 |
NPT1033 |
Organism |
Enterobacter cloacae |
Enterobacter cloacae |
IZ |
= |
0 |
mm |
17638702 |
NPT1033 |
Organism |
Enterobacter cloacae |
Enterobacter cloacae |
IZ |
= |
14 |
mm |
17638702 |
NPT1033 |
Organism |
Enterobacter cloacae |
Enterobacter cloacae |
IZ |
= |
16 |
mm |
17638702 |
NPT1033 |
Organism |
Enterobacter cloacae |
Enterobacter cloacae |
IZ |
= |
20 |
mm |
17638702 |
NPT1033 |
Organism |
Enterobacter cloacae |
Enterobacter cloacae |
IZ |
= |
22 |
mm |
17638702 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.125 |
ug/ml |
17502406 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
17502406 |
NPT519 |
Cell Line |
SH-SY5Y |
Homo sapiens |
EC50 |
= |
48.39 |
nM |
19138859 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.125 |
ug/ml |
17876001 |
NPT1863 |
Organism |
Staphylococcus saprophyticus |
Staphylococcus saprophyticus |
MIC |
= |
16 |
ug/ml |
17876001 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
8 |
ug/ml |
17876001 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
1 |
ug/ml |
17876001 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
2 |
ug/ml |
17876001 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
64 |
|
17876001 |
NPT2 |
Others |
Unspecified |
|
IC50 |
< |
1000 |
nM |
19477652 |
NPT5485 |
Organism |
Mycobacterium leprae |
Mycobacterium leprae |
IC50 |
= |
0.25 |
ug/ml |
18070975 |
NPT5485 |
Organism |
Mycobacterium leprae |
Mycobacterium leprae |
IC50 |
= |
0.3 |
ug/ml |
18070975 |
NPT5485 |
Organism |
Mycobacterium leprae |
Mycobacterium leprae |
IC50 |
= |
0.2 |
ug/ml |
18070975 |
NPT196 |
Cell Line |
AGS |
Homo sapiens |
Activity |
= |
63 |
% |
18847278 |
NPT196 |
Cell Line |
AGS |
Homo sapiens |
Activity |
= |
72 |
% |
18847278 |
NPT2 |
Others |
Unspecified |
|
EC50 |
= |
100000 |
nM |
20014866 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.125 |
ug/ml |
19683922 |
NPT1228 |
Organism |
Streptococcus pyogenes |
Streptococcus pyogenes |
MIC |
= |
8 |
ug/ml |
19683922 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
4 |
ug/ml |
19683922 |
NPT5486 |
Individual Protein |
DNA gyrase subunit B |
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) |
IC50 |
= |
37 |
nM |
19683922 |
NPT5487 |
Individual Protein |
ParE |
Streptococcus pneumoniae |
IC50 |
= |
2030 |
nM |
19683922 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
IC50 |
= |
125 |
nM |
19683922 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
4000 |
ug/ml |
19683922 |
NPT1422 |
Individual Protein |
ATP-binding cassette sub-family G member 2 |
Homo sapiens |
IC50 |
= |
85100 |
nM |
19932960 |
NPT1422 |
Individual Protein |
ATP-binding cassette sub-family G member 2 |
Homo sapiens |
IC50 |
= |
104000 |
nM |
19932960 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
3 |
nM |
20045642 |
NPT134 |
Cell Line |
SK-BR-3 |
Homo sapiens |
IC50 |
= |
700000 |
nM |
19932969 |
NPT1466 |
Organism |
Escherichia coli K12 |
Escherichia coli K-12 |
MIC |
= |
128 |
ug/ml |
20138759 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.125 |
ug/ml |
20188576 |
NPT447 |
Organism |
Streptomyces |
Streptomyces |
IZ |
= |
20 |
mm |
20384319 |
NPT447 |
Organism |
Streptomyces |
Streptomyces |
IZ |
= |
18 |
mm |
20384319 |
NPT447 |
Organism |
Streptomyces |
Streptomyces |
IZ |
= |
15 |
mm |
20384319 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
IC50 |
= |
481300 |
nM |
20570149 |
NPT134 |
Cell Line |
SK-BR-3 |
Homo sapiens |
IC50 |
= |
474700 |
nM |
20570149 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
500 |
ug/ml |
19884363 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
40 |
ug/ml |
19884363 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
20655215 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
0.125 |
ug/ml |
20655215 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.125 |
ug/ml |
20655215 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
50 |
nM |
20655215 |
NPT1548 |
Organism |
Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
MIC |
= |
16 |
ug/ml |
20655215 |
NPT1466 |
Organism |
Escherichia coli K12 |
Escherichia coli K-12 |
MIC |
= |
8 |
ug/ml |
20655215 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
4 |
ug/ml |
20038628 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
8 |
ug/ml |
20038628 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
512 |
ug/ml |
20038628 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
800 |
nM |
18268084 |
NPT1567 |
Protein Complex |
DNA gyrase |
Escherichia coli K-12 |
IC50 |
= |
100 |
nM |
18268084 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
100 |
nM |
18268084 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
4 |
ug/ml |
20211889 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
16 |
ug/ml |
20211889 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
2 |
ug/ml |
20211889 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
8 |
ug/ml |
20211889 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
800 |
ug/ml |
18676884 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
200 |
ug/ml |
18676884 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
> |
1200 |
ug/ml |
18676884 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
12.5 |
ug/ml |
18676884 |
NPT312 |
Organism |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
IZ |
= |
0 |
mm |
20739103 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
512 |
ug/ml |
18694955 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
256 |
ug/ml |
18694955 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
64 |
ug/ml |
18694955 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
1024 |
ug/ml |
18694955 |
NPT746 |
Organism |
Pasteurella multocida |
Pasteurella multocida |
MIC |
= |
40 |
ug/ml |
18725450 |
NPT746 |
Organism |
Pasteurella multocida |
Pasteurella multocida |
MIC |
= |
2.5 |
ug/ml |
18725450 |
NPT746 |
Organism |
Pasteurella multocida |
Pasteurella multocida |
Ratio |
= |
16 |
|
18725450 |
NPT746 |
Organism |
Pasteurella multocida |
Pasteurella multocida |
MIC |
= |
20 |
ug/ml |
18725450 |
NPT746 |
Organism |
Pasteurella multocida |
Pasteurella multocida |
Ratio |
= |
2 |
|
18725450 |
NPT602 |
Organism |
Mycobacterium smegmatis |
Mycobacterium smegmatis |
MIC |
= |
4 |
ug/ml |
18458127 |
NPT602 |
Organism |
Mycobacterium smegmatis |
Mycobacterium smegmatis |
MIC |
= |
8 |
ug/ml |
18458127 |
NPT602 |
Organism |
Mycobacterium smegmatis |
Mycobacterium smegmatis |
Ratio |
= |
2 |
|
18458127 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
1600 |
ug/ml |
18285485 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
140 |
ug/ml |
18285485 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
FC |
= |
100000000 |
|
18285485 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
> |
32 |
ug/ml |
18347114 |
NPT1531 |
Organism |
Enterococcus faecium |
Enterococcus faecium |
MIC |
> |
32 |
ug/ml |
18347114 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC |
> |
32 |
ug/ml |
18347114 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
2 |
ug/ml |
18347114 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
1 |
ug/ml |
18347114 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
> |
32 |
ug/ml |
18347114 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
18347114 |
NPT4941 |
Individual Protein |
Cell division inhibitor sulA |
Escherichia coli K-12 |
Activity |
= |
6.3 |
nM |
18347114 |
NPT4942 |
Individual Protein |
DNA gyrase subunit A |
Escherichia coli K-12 |
Activity |
= |
3.1 |
nM |
18347114 |
NPT4940 |
Individual Protein |
DNA gyrase subunit B |
Escherichia coli K-12 |
Ratio IC50 |
= |
0.8 |
|
18347114 |
NPT4940 |
Individual Protein |
DNA gyrase subunit B |
Escherichia coli K-12 |
IC50 |
= |
200 |
nM |
18347114 |
NPT4940 |
Individual Protein |
DNA gyrase subunit B |
Escherichia coli K-12 |
IC50 |
= |
154 |
nM |
18347114 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
4 |
ug/ml |
18347114 |
NPT173 |
Organism |
Klebsiella pneumoniae |
Klebsiella pneumoniae |
MIC |
> |
32 |
ug/ml |
18347114 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
> |
32 |
ug/ml |
18347114 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
1 |
ug/ml |
18347114 |
NPT1101 |
Organism |
Staphylococcus aureus subsp. aureus RN4220 |
Staphylococcus aureus subsp. aureus RN4220 |
MIC |
= |
0.125 |
ug/ml |
18519725 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.00125 |
ug/ml |
18519725 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.625 |
ug/ml |
18519725 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
100 |
nM |
18519725 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
1000 |
nM |
18519725 |
NPT173 |
Organism |
Klebsiella pneumoniae |
Klebsiella pneumoniae |
IZ |
= |
9 |
mm |
19015361 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.049 |
ug/ml |
19164148 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
1024 |
ug/ml |
19164148 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
256 |
ug/ml |
19164148 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
2 |
ug/ml |
19164148 |
NPT604 |
Individual Protein |
Serum albumin |
Homo sapiens |
Kd |
= |
12000 |
nM |
19164148 |
NPT604 |
Individual Protein |
Serum albumin |
Homo sapiens |
Ratio |
= |
0.5 |
|
19164148 |
NPT604 |
Individual Protein |
Serum albumin |
Homo sapiens |
Ratio |
= |
1 |
|
19164148 |
NPT604 |
Individual Protein |
Serum albumin |
Homo sapiens |
Ratio |
= |
1.5 |
|
19164148 |
NPT604 |
Individual Protein |
Serum albumin |
Homo sapiens |
Ratio |
= |
2 |
|
19164148 |
NPT1548 |
Organism |
Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
MIC |
= |
512 |
ug/ml |
19258280 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
512 |
ug/ml |
19258280 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
64 |
ug/ml |
19258280 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
4 |
ug/ml |
19258280 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
16 |
ug/ml |
19258280 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
32 |
ug/ml |
19258280 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
MIC |
= |
8 |
ug/ml |
19258280 |
NPT1548 |
Organism |
Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
MIC |
= |
32 |
ug/ml |
19258280 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
FC |
= |
16 |
|
19258280 |
NPT566 |
Organism |
Salmonella typhimurium |
Salmonella enterica subsp. enterica serovar Typhimurium |
MIC |
= |
256 |
ug/ml |
19470505 |
NPT566 |
Organism |
Salmonella typhimurium |
Salmonella enterica subsp. enterica serovar Typhimurium |
MIC |
= |
128 |
ug/ml |
19470505 |
NPT88 |
Organism |
Mycobacterium tuberculosis |
Mycobacterium tuberculosis |
FC |
>= |
2 |
|
19564371 |
NPT1108 |
Organism |
Mycobacterium bovis BCG |
Mycobacterium bovis BCG |
MIC |
= |
16 |
ug/ml |
19564371 |
NPT1108 |
Organism |
Mycobacterium bovis BCG |
Mycobacterium bovis BCG |
MIC |
= |
2 |
ug/ml |
19564371 |
NPT1108 |
Organism |
Mycobacterium bovis BCG |
Mycobacterium bovis BCG |
MIC |
= |
4 |
ug/ml |
19564371 |
NPT1108 |
Organism |
Mycobacterium bovis BCG |
Mycobacterium bovis BCG |
MIC |
= |
1 |
ug/ml |
19564371 |
NPT1108 |
Organism |
Mycobacterium bovis BCG |
Mycobacterium bovis BCG |
MIC |
= |
8 |
ug/ml |
19564371 |
NPT1108 |
Organism |
Mycobacterium bovis BCG |
Mycobacterium bovis BCG |
MIC |
= |
0.5 |
ug/ml |
19564371 |
NPT1108 |
Organism |
Mycobacterium bovis BCG |
Mycobacterium bovis BCG |
Ratio |
= |
4 |
|
19564371 |
NPT858 |
Cell Line |
LNCaP |
Homo sapiens |
IC50 |
= |
420000 |
nM |
21129982 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
1050 |
nM |
21129982 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
3.125 |
ug/ml |
18591276 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
1.56 |
ug/ml |
18591276 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
4 |
ug/ml |
19770280 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
< |
0.5 |
ug/ml |
19770280 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
20 |
ug/ml |
19770280 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Ratio |
= |
5 |
|
19770280 |
NPT747 |
Organism |
Acinetobacter baumannii |
Acinetobacter baumannii |
MIC |
= |
120 |
ug/ml |
19770280 |
NPT747 |
Organism |
Acinetobacter baumannii |
Acinetobacter baumannii |
MIC |
= |
40 |
ug/ml |
19770280 |
NPT747 |
Organism |
Acinetobacter baumannii |
Acinetobacter baumannii |
Ratio |
= |
3 |
|
19770280 |
NPT747 |
Organism |
Acinetobacter baumannii |
Acinetobacter baumannii |
MIC |
= |
84 |
ug/ml |
19770280 |
NPT1466 |
Organism |
Escherichia coli K12 |
Escherichia coli K-12 |
Ratio |
= |
4 |
|
18936189 |
NPT1466 |
Organism |
Escherichia coli K12 |
Escherichia coli K-12 |
MIC |
= |
512 |
ug/ml |
18936189 |
NPT1466 |
Organism |
Escherichia coli K12 |
Escherichia coli K-12 |
MIC |
= |
4 |
ug/ml |
18936189 |
NPT1466 |
Organism |
Escherichia coli K12 |
Escherichia coli K-12 |
MIC |
= |
1024 |
ug/ml |
18936189 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
32 |
ug/ml |
20876376 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
1 |
ug/ml |
20876376 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
64 |
ug/ml |
20876376 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
256 |
ug/ml |
20876376 |
NPT5 |
Individual Protein |
Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 |
Homo sapiens |
Potency |
|
19952.6 |
nM |
PubChem BioAssay data set |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
> |
64 |
ug/ml |
21388139 |
NPT1521 |
Organism |
Stenotrophomonas maltophilia |
Stenotrophomonas maltophilia |
MIC |
> |
64 |
ug/ml |
21388139 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
21388139 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.12 |
ug/ml |
21388139 |
NPT17 |
Organism |
Staphylococcus epidermidis |
Staphylococcus epidermidis |
MIC |
= |
0.25 |
ug/ml |
21388139 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC |
= |
4 |
ug/ml |
21388139 |
NPT1228 |
Organism |
Streptococcus pyogenes |
Streptococcus pyogenes |
MIC |
= |
1 |
ug/ml |
21388139 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
ED50 |
= |
3 |
mg/kg |
21388139 |
NPT1429 |
Individual Protein |
Heat shock protein HSP 90-beta |
Homo sapiens |
Activity |
= |
0.7 |
nM |
21904660 |
NPT4310 |
Individual Protein |
Heat shock protein HSP 90 |
Oryctolagus cuniculus |
IC50 |
= |
350000 |
nM |
21273068 |
NPT1044 |
Individual Protein |
DNA topoisomerase II alpha |
Homo sapiens |
Inhibition |
= |
60.4 |
% |
21419530 |
NPT1605 |
Organism |
Enterococcus |
Enterococcus |
MIC |
> |
128 |
ug/ml |
21534606 |
NPT1605 |
Organism |
Enterococcus |
Enterococcus |
MIC |
= |
2 |
ug/ml |
21534606 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
8 |
ug/ml |
21534606 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
21534606 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
0.13 |
ug/ml |
21534606 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.13 |
ug/ml |
21534606 |
NPT1624 |
Organism |
Streptococcus pneumoniae R6 |
Streptococcus pneumoniae R6 |
MIC |
= |
0.25 |
ug/ml |
21534606 |
NPT1548 |
Organism |
Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
MIC |
= |
8 |
ug/ml |
21534606 |
NPT1466 |
Organism |
Escherichia coli K12 |
Escherichia coli K-12 |
MIC |
= |
8 |
ug/ml |
21534606 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
50 |
nM |
21534606 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
110 |
nM |
21534606 |
NPT134 |
Cell Line |
SK-BR-3 |
Homo sapiens |
IC50 |
= |
700000 |
nM |
21553822 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
90 |
% |
21486005 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
8 |
nM |
21871799 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.125 |
ug/ml |
21871799 |
NPT790 |
Organism |
Mycobacterium tuberculosis H37Rv |
Mycobacterium tuberculosis H37Rv |
MIC |
= |
4 |
ug/ml |
21871799 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
2 |
ug/ml |
21871799 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
4 |
ug/ml |
21871799 |
NPT901 |
Individual Protein |
UDP-glucuronosyltransferase 1-1 |
Homo sapiens |
Activity |
= |
0 |
pm/min/mg |
10836148 |
NPT15 |
Cell Line |
Jurkat |
Homo sapiens |
Activity |
= |
0.7 |
nM |
22014826 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
3 |
nM |
22444877 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
15 |
nM |
22444877 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Ratio |
= |
32 |
|
22483632 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
Ratio |
= |
64 |
|
22483632 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
32 |
ug/ml |
22483632 |
NPT2 |
Others |
Unspecified |
|
Ki |
= |
60000 |
nM |
22424148 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
780 |
nM |
22814212 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
390 |
nM |
22814212 |
NPT1422 |
Individual Protein |
ATP-binding cassette sub-family G member 2 |
Homo sapiens |
Activity |
= |
3 |
fold |
16460798 |
NPT1422 |
Individual Protein |
ATP-binding cassette sub-family G member 2 |
Homo sapiens |
IC50 |
= |
25000 |
nM |
16460798 |
NPT2 |
Others |
Unspecified |
|
Kd |
= |
28 |
nM |
22731783 |
NPT622 |
Individual Protein |
Solute carrier organic anion transporter family member 2B1 |
Homo sapiens |
Inhibition |
= |
85.6 |
% |
22541068 |
NPT72 |
Individual Protein |
Solute carrier organic anion transporter family member 1B3 |
Homo sapiens |
Inhibition |
= |
84.2 |
% |
22541068 |
NPT73 |
Individual Protein |
Solute carrier organic anion transporter family member 1B1 |
Homo sapiens |
Inhibition |
= |
58.1 |
% |
22541068 |
NPT2 |
Others |
Unspecified |
|
Kd |
= |
120000 |
nM |
21235241 |
NPT4943 |
Individual Protein |
DNA gyrase subunit B |
Escherichia coli |
Kd |
= |
28 |
nM |
21235241 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
210 |
nM |
21235241 |
NPT20 |
Organism |
Candida albicans |
Candida albicans |
MIC |
> |
32 |
ug/ml |
23084277 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
> |
32 |
ug/ml |
23084277 |
NPT5484 |
Protein Complex |
DNA gyrase |
Staphylococcus aureus |
IC50 |
< |
4 |
nM |
23084277 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
35000 |
nM |
23084277 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
10000 |
nM |
23084277 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
500 |
nM |
23084277 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
450 |
nM |
23084277 |
NPT175 |
Organism |
Enterococcus faecalis |
Enterococcus faecalis |
MIC |
= |
32 |
ug/ml |
23084277 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
23 |
nM |
23084277 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
16 |
ug/ml |
23084277 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
4 |
ug/ml |
23084277 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
2 |
ug/ml |
23084277 |
NPT79 |
Organism |
Bacillus subtilis |
Bacillus subtilis |
MIC |
= |
2 |
ug/ml |
23084277 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
1 |
ug/ml |
23084277 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.5 |
ug/ml |
23084277 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.25 |
ug/ml |
23084277 |
NPT1122 |
Organism |
Haemophilus influenzae |
Haemophilus influenzae |
MIC |
= |
0.12 |
ug/ml |
23084277 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.06 |
ug/ml |
23084277 |
NPT2758 |
Organism |
Streptomyces alboniger |
Streptomyces alboniger |
IZ |
= |
11 |
mm |
10.1584/jpestics.28.183 |
NPT2758 |
Organism |
Streptomyces alboniger |
Streptomyces alboniger |
IZ |
= |
21 |
mm |
10.1584/jpestics.28.183 |
NPT2759 |
Organism |
Streptomyces acidiscabies |
Streptomyces acidiscabies |
IZ |
= |
18 |
mm |
10.1584/jpestics.28.183 |
NPT2759 |
Organism |
Streptomyces acidiscabies |
Streptomyces acidiscabies |
IZ |
= |
14 |
mm |
10.1584/jpestics.28.183 |
NPT2759 |
Organism |
Streptomyces acidiscabies |
Streptomyces acidiscabies |
IZ |
= |
39 |
mm |
10.1584/jpestics.28.183 |
NPT2760 |
Organism |
Streptomyces scabiei |
Streptomyces scabiei |
IZ |
= |
17 |
mm |
10.1584/jpestics.28.183 |
NPT2760 |
Organism |
Streptomyces scabiei |
Streptomyces scabiei |
IZ |
= |
26 |
mm |
10.1584/jpestics.28.183 |
NPT2760 |
Organism |
Streptomyces scabiei |
Streptomyces scabiei |
IZ |
= |
44 |
mm |
10.1584/jpestics.28.183 |
NPT2760 |
Organism |
Streptomyces scabiei |
Streptomyces scabiei |
IZ |
= |
28 |
mm |
10.1584/jpestics.28.183 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
77.9 |
% |
23441911 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
78.2 |
% |
23441911 |
NPT1 |
Others |
Radical scavenging activity |
|
Activity |
= |
47.7 |
% |
23441911 |
NPT79 |
Organism |
Bacillus subtilis |
Bacillus subtilis |
MIC |
= |
16 |
ug/ml |
23441911 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
64 |
ug/ml |
23441911 |
NPT826 |
Organism |
Magnaporthe oryzae |
Magnaporthe oryzae |
MIC |
= |
16 |
ug/ml |
23441911 |
NPT134 |
Cell Line |
SK-BR-3 |
Homo sapiens |
IC50 |
= |
700000 |
nM |
23234644 |
NPT134 |
Cell Line |
SK-BR-3 |
Homo sapiens |
IC50 |
= |
700000 |
nM |
23606927 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
32 |
ug/ml |
23409840 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
0.5 |
ug/ml |
23409840 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
IC50 |
= |
357000 |
nM |
23859777 |
NPT134 |
Cell Line |
SK-BR-3 |
Homo sapiens |
IC50 |
= |
350000 |
nM |
23859777 |
NPT134 |
Cell Line |
SK-BR-3 |
Homo sapiens |
Activity |
= |
57 |
% |
23859777 |
NPT134 |
Cell Line |
SK-BR-3 |
Homo sapiens |
Activity |
= |
38 |
% |
23859777 |
NPT134 |
Cell Line |
SK-BR-3 |
Homo sapiens |
Activity |
= |
15 |
% |
23859777 |
NPT134 |
Cell Line |
SK-BR-3 |
Homo sapiens |
Activity |
= |
10 |
% |
23859777 |
NPT2 |
Others |
Unspecified |
|
FC |
= |
1.5 |
|
23859777 |
NPT1044 |
Individual Protein |
DNA topoisomerase II alpha |
Homo sapiens |
Inhibition |
= |
76.8 |
% |
24013413 |
NPT1044 |
Individual Protein |
DNA topoisomerase II alpha |
Homo sapiens |
Inhibition |
= |
63.6 |
% |
24013413 |
NPT1044 |
Individual Protein |
DNA topoisomerase II alpha |
Homo sapiens |
Inhibition |
= |
14.4 |
% |
24013413 |
NPT1166 |
Individual Protein |
Angiotensin-converting enzyme |
Homo sapiens |
Ki |
= |
167000 |
nM |
24088053 |
NPT1166 |
Individual Protein |
Angiotensin-converting enzyme |
Homo sapiens |
Inhibition |
= |
75 |
% |
24088053 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
50 |
nM |
24148991 |
NPT790 |
Organism |
Mycobacterium tuberculosis H37Rv |
Mycobacterium tuberculosis H37Rv |
MIC |
> |
200000 |
nM |
24148991 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
100 |
% |
24148991 |
NPT5489 |
Individual Protein |
DNA gyrase subunit B |
Mycobacterium smegmatis |
IC50 |
= |
200 |
nM |
24148991 |
NPT5489 |
Individual Protein |
DNA gyrase subunit B |
Mycobacterium smegmatis |
Inhibition |
= |
96 |
% |
24148991 |
NPT5489 |
Individual Protein |
DNA gyrase subunit B |
Mycobacterium smegmatis |
Inhibition |
= |
98.2 |
% |
24148991 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
700000 |
nM |
24900777 |
NPT2 |
Others |
Unspecified |
|
Potency |
|
18821.2 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
14950.2 |
nM |
PubChem BioAssay data set |
NPT49 |
Individual Protein |
DNA-(apurinic or apyrimidinic site) lyase |
Homo sapiens |
Potency |
|
10 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
11875.4 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
5951.8 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
700000 |
nM |
10.1039/C0MD00063A |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
< |
1.95 |
ug/ml |
24629449 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
< |
1270 |
nM |
24629449 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
0.5 |
ug/ml |
24098982 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
2 |
ug/ml |
24098982 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
1 |
ug/ml |
24098982 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
0.25 |
ug/ml |
24098982 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
4 |
ug/ml |
24098982 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
8 |
|
24098982 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
4 |
|
24098982 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
1 |
|
24098982 |
NPT2 |
Others |
Unspecified |
|
Ratio |
= |
16 |
|
24098982 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
IC50 |
= |
260000 |
nM |
24992077 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
GI50 |
= |
260000 |
nM |
24992077 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC80 |
= |
0.3 |
ug/ml |
24746270 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC80 |
= |
0.1 |
ug/ml |
24746270 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
700000 |
nM |
25462258 |
NPT5489 |
Individual Protein |
DNA gyrase subunit B |
Mycobacterium smegmatis |
IC50 |
= |
180 |
nM |
25456076 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
46 |
nM |
25456076 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
46000 |
nM |
25127151 |
NPT790 |
Organism |
Mycobacterium tuberculosis H37Rv |
Mycobacterium tuberculosis H37Rv |
MIC |
> |
200000 |
nM |
25127151 |
NPT113 |
Cell Line |
RAW264.7 |
Mus musculus |
Inhibition |
= |
29.44 |
% |
25127151 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
700000000 |
nM |
24953820 |
NPT4310 |
Individual Protein |
Heat shock protein HSP 90 |
Oryctolagus cuniculus |
IC50 |
= |
414000 |
nM |
24984936 |
NPT1429 |
Individual Protein |
Heat shock protein HSP 90-beta |
Homo sapiens |
IC50 |
= |
231000 |
nM |
24984936 |
NPT2 |
Others |
Unspecified |
|
LC50 |
= |
690000 |
nM |
24984936 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.13 |
ug/ml |
25286019 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
32 |
ug/ml |
25286019 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
4.3 |
ug/ml |
25286019 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
1 |
ug/ml |
25286019 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
> |
16 |
ug/ml |
25286019 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
0.13 |
ug/ml |
25286019 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
> |
61 |
% |
25127151 |
NPT5490 |
Individual Protein |
DNA gyrase subunit B |
Staphylococcus aureus |
IC50 |
= |
125 |
nM |
25288496 |
NPT5484 |
Protein Complex |
DNA gyrase |
Staphylococcus aureus |
IC50 |
= |
30 |
nM |
25288496 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
250 |
nM |
25288496 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
15 |
nM |
25221657 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
46 |
nM |
25129171 |
NPT5489 |
Individual Protein |
DNA gyrase subunit B |
Mycobacterium smegmatis |
IC50 |
= |
180 |
nM |
25129171 |
NPT790 |
Organism |
Mycobacterium tuberculosis H37Rv |
Mycobacterium tuberculosis H37Rv |
MIC |
> |
200000 |
nM |
25129171 |
NPT113 |
Cell Line |
RAW264.7 |
Mus musculus |
Inhibition |
= |
19.36 |
% |
25129171 |
NPT5489 |
Individual Protein |
DNA gyrase subunit B |
Mycobacterium smegmatis |
IC50 |
= |
180 |
nM |
25801151 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
46 |
nM |
25801151 |
NPT790 |
Organism |
Mycobacterium tuberculosis H37Rv |
Mycobacterium tuberculosis H37Rv |
MIC |
> |
200000 |
nM |
25801151 |
NPT5489 |
Individual Protein |
DNA gyrase subunit B |
Mycobacterium smegmatis |
IC50 |
= |
46 |
nM |
25766629 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
180 |
nM |
25766629 |
NPT113 |
Cell Line |
RAW264.7 |
Mus musculus |
Inhibition |
= |
81.67 |
% |
25766629 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
700000 |
nM |
25699150 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
320000 |
nM |
25941556 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
MIC |
= |
1200 |
nM |
25941556 |
NPT1567 |
Protein Complex |
DNA gyrase |
Escherichia coli K-12 |
IC50 |
= |
170 |
nM |
26098163 |
NPT5484 |
Protein Complex |
DNA gyrase |
Staphylococcus aureus |
IC50 |
= |
40 |
nM |
26098163 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
11000 |
nM |
26098163 |
NPT5491 |
Protein Complex |
Topoisomerase IV |
Staphylococcus aureus |
IC50 |
= |
27000 |
nM |
26098163 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
130 |
nM |
26098163 |
NPT1567 |
Protein Complex |
DNA gyrase |
Escherichia coli K-12 |
IC50 |
= |
80 |
nM |
26098163 |
NPT5484 |
Protein Complex |
DNA gyrase |
Staphylococcus aureus |
IC50 |
= |
10 |
nM |
26098163 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
10000 |
nM |
26098163 |
NPT5491 |
Protein Complex |
Topoisomerase IV |
Staphylococcus aureus |
IC50 |
= |
20000 |
nM |
26098163 |
NPT2 |
Others |
Unspecified |
|
MIC |
= |
2500 |
nM |
26320664 |
NPT5484 |
Protein Complex |
DNA gyrase |
Staphylococcus aureus |
MIC |
= |
10 |
nM |
26320664 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
46 |
nM |
26318054 |
NPT5489 |
Individual Protein |
DNA gyrase subunit B |
Mycobacterium smegmatis |
IC50 |
= |
180 |
nM |
26318054 |
NPT790 |
Organism |
Mycobacterium tuberculosis H37Rv |
Mycobacterium tuberculosis H37Rv |
MIC |
> |
200000 |
nM |
26318054 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
ED |
> |
100 |
mg/kg |
26487916 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
MIC |
= |
0.125 |
ug/ml |
26487916 |
NPT1118 |
Organism |
Streptococcus pneumoniae |
Streptococcus pneumoniae |
MIC |
= |
2 |
ug/ml |
26487916 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
46000 |
nM |
26678175 |
NPT790 |
Organism |
Mycobacterium tuberculosis H37Rv |
Mycobacterium tuberculosis H37Rv |
MIC |
> |
200000 |
nM |
26678175 |
NPT113 |
Cell Line |
RAW264.7 |
Mus musculus |
Inhibition |
= |
19.3 |
% |
26678175 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
46 |
nM |
26787274 |
NPT790 |
Organism |
Mycobacterium tuberculosis H37Rv |
Mycobacterium tuberculosis H37Rv |
MIC |
> |
50000 |
nM |
26787274 |
NPT5492 |
Organism |
Proteus sp. |
Proteus sp. |
IZ |
= |
20 |
mm |
26833242 |
NPT19 |
Organism |
Escherichia coli |
Escherichia coli |
IZ |
= |
7 |
mm |
26833242 |
NPT18 |
Organism |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa |
IZ |
= |
14 |
mm |
26833242 |
NPT16 |
Organism |
Staphylococcus aureus |
Staphylococcus aureus |
IZ |
= |
24 |
mm |
26833242 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
700000 |
nM |
26745854 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
26700 |
nM |
27100032 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
11100 |
nM |
27100032 |
NPT5484 |
Protein Complex |
DNA gyrase |
Staphylococcus aureus |
IC50 |
= |
41 |
nM |
27100032 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
168 |
nM |
27100032 |
NPT2 |
Others |
Unspecified |
|
Kd |
= |
28 |
nM |
27100032 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
80 |
nM |
27100032 |
NPT5484 |
Protein Complex |
DNA gyrase |
Staphylococcus aureus |
IC50 |
= |
10 |
nM |
27100032 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
10000 |
nM |
27100032 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
20000 |
nM |
27100032 |
NPT2 |
Others |
Unspecified |
|
Kd |
= |
19 |
nM |
27100032 |
NPT83 |
Cell Line |
MCF7 |
Homo sapiens |
IC50 |
= |
293300 |
nM |
27153346 |
NPT784 |
Cell Line |
MDA-MB-468 |
Homo sapiens |
IC50 |
= |
338400 |
nM |
27153346 |