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Collective Molecular Activities of the Plant: Cheilanthes Fragrans


Example Image
PLANiTS DNA barcode

Click for details-----ITS

NA

Click for details-----ITS1

NA

Click for details-----ITS2

NA
Taxonomic Information

Plant ID: NPO20584
Plant Latin Name: Cheilanthes Fragrans
Taxonomy Genus: Cheilanthes
Taxonomy Family: Pteridaceae

Plant External Links:

NCBI TaxonomyDB: n.a.
Plant-of-the-World-Online: n.a.

Used in Medicines

Country/Region:
India

Traditional Medicine System:
Indian Folk

Geographical Distribution

India

Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Compounds Summary

Overview of Ingredients

36 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.


22 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)

22 Ingredients with experimental-derived Activity

Unique ingredients have activity data available.





Ingredient Structrual Cards

Ingredient ID: NPC98702

Ingredient ID: NPC95090

Ingredient ID: NPC72452

Ingredient ID: NPC70853

Ingredient ID: NPC6908

Ingredient ID: NPC65197

Ingredient ID: NPC61546

Ingredient ID: NPC40379

Ingredient ID: NPC39633

Ingredient ID: NPC310259

Ingredient ID: NPC295580

Ingredient ID: NPC294815

Ingredient ID: NPC29353

Ingredient ID: NPC278556

Ingredient ID: NPC272958

Ingredient ID: NPC270620

Ingredient ID: NPC262094

Ingredient ID: NPC255840

Ingredient ID: NPC2556

Ingredient ID: NPC254133

Ingredient ID: NPC234133

Ingredient ID: NPC232302

Ingredient ID: NPC231410

Ingredient ID: NPC206102

Ingredient ID: NPC195202

Ingredient ID: NPC188646

Ingredient ID: NPC179726

Ingredient ID: NPC176740

Ingredient ID: NPC156461

Ingredient ID: NPC150648

Ingredient ID: NPC143190

Ingredient ID: NPC127447

Ingredient ID: NPC120320

Ingredient ID: NPC10781

Ingredient ID: NPC103904

Ingredient ID: NPC101294

Classification of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 1μM
Target Type: Individual Protein of Homo sapiens
*The classification criteria of Drug Transporter (DTP), CYP450 are referred to DrugMap. Other molecular targets in CMAUP are classified as therapeutic targets.
.

Detailed Information of Target Proteins

Target Type Protein Class Gene ID Protein Name Uniprot ID Target ChEMBL ID
Drug Transporter ATP-binding cassette ABCG2 ATP-binding cassette sub-family G member 2 Q9UNQ0 CHEMBL5393
Cytochrome P450 Cytochrome P450 family 2 CYP2C19 Cytochrome P450 2C19 P33261 CHEMBL3622
Therapeutic Target Hydrolase ACHE Acetylcholinesterase P22303 CHEMBL220
Therapeutic Target Protein Kinase MKNK2 MAP kinase signal-integrating kinase 2 Q9HBH9 CHEMBL4204
Therapeutic Target Small molecule receptor (family A GPCR) ADORA1 Adenosine A1 receptor P30542 CHEMBL226
Therapeutic Target Small molecule receptor (family A GPCR) ADORA2A Adenosine A2a receptor P29274 CHEMBL251
Therapeutic Target Small molecule receptor (family A GPCR) ADORA3 Adenosine A3 receptor P0DMS8 CHEMBL256
Clinical Trials Summary
Overview

Clinical trials associated with plant from natural product (NP) & plant level:

Clinical trials type Number of clinical trials
NP level27
Clinical trial details
NCT ID Title Condition Form in clinical use Associated by plant or compound
NCT00751491 Clopidogrel Versus Adenosin in Non Urgent Percutaneous Coronary Intervention (PCI) angina pectoris Adenosine (NPC156461) NP level
NCT01690884 Effect of Ticagrelor vs. Dipyridamole on Adenosine Uptake coronary artery disease Adenosine (NPC156461) NP level
NCT00612521 Prophylactic Intra-coronary Adenosine to Prevent Post Coronary Artery Stenting Myonecrosis coronary stenosis Adenosine (NPC156461) NP level
NCT01123525 Adenosine Cardioplegia angina pectoris Adenosine (NPC156461) NP level
NCT00580905 Role of Adenosine in the Release of VEGF and Cytokines inflammation Adenosine (NPC156461) NP level
NCT02681913 Adenosine as an Adjunct to Blood Cardioplegia cardiomyopathy Adenosine (NPC156461) NP level
NCT04392362 A Trial to Compare American Heart Association (AHA) and Simple (SIM)Method to Give Adenosine to Treat Supra-ventricular Tachycardia (SVT) ventricular tachycardia Adenosine (NPC156461) NP level
NCT00781404 Myocardial Protection With Adenosine During Primary Percutaneous Coronary Intervention in Pts With STEMI acute myocardial infarction Adenosine (NPC156461) NP level
NCT00298636 Dose-Response of Adenosine for Perioperative Pain pain Adenosine (NPC156461) NP level
NCT01593644 Phase II Study for the Diagnosis and Functional Assessment of CAD Using Transthoracic-Echodoppler coronary artery disease Adenosine (NPC156461) NP level
NCT00565188 Application of ATP Infusions in Palliative Home Care cancer Adenosine (NPC156461) NP level
NCT00845689 Prevention of Liver Damage During Liver Surgery neoplasm Adenosine (NPC156461) NP level
NCT01705652 Study to Assess the Activity of Nexrutine® in Prostate Cancer Patients prostate cancer Rutin (NPC176740) NP level
NCT02867878 Adenosin to Rapidly Reverse Left Ventricle Impairment in Takotsubo Syndrome Takotsubo cardiomyopathy Adenosine (NPC156461) NP level
NCT03032965 Adenosine to Assess Complete Conduction Block During Catheter Ablation of Paroxysmal Atrial Fibrillation atrial fibrillation Adenosine (NPC156461) NP level
NCT04666454 BROKEN-SWEDEHEART-Optimized Pharmacological Treatment for Broken Heart (Takotsubo) Syndrome Takotsubo cardiomyopathy Adenosine (NPC156461) NP level
NCT05014061 Adenosine's Effect on STunning Resolution in Acute Myocardial Infarction Myocardial Ischemia Adenosine (NPC156461) NP level
NCT00590070 THE REOPEN-AMI STUDY - Intracoronary Nitroprusside Versus Adenosine in Acute Myocardial Infarction myocardial infarction Adenosine (NPC156461) NP level
NCT01233492 Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme Central Nervous System Neoplasm L-Phenylalanine (NPC10781) NP level
NCT00284323 Salvage: Postconditioning With Adenosine for STEMI ST Elevation Myocardial Infarction Adenosine (NPC156461) NP level
NCT03236311 A Dose Titration Study to Assess the Effects of SAR407899 in Patients With MVA and/or Persistent Stable Angina Despite Angiographically Successful PCI coronary artery disease Adenosine (NPC156461) NP level
NCT00179010 AMP as a Better Delivery System of Adenosine ischemia Adenosine (NPC156461) NP level
NCT04588441 The ARCTIC Trial: Aerosolized Inhaled Adenosine Treatment in Patients With Acute Respiratory Distress Syndrome (ARDS) Caused by COVID-19 acute respiratory distress syndrome Adenosine (NPC156461) NP level
NCT00349921 Clonidine Versus Adenosine to Treat Neuropathic Pain pain Adenosine (NPC156461) NP level
NCT01747174 REperfusion Facilitated by LOcal Adjunctive Therapy in ST-elevation Myocardial Infarction ST Elevation Myocardial Infarction Adenosine (NPC156461) NP level
NCT00714103 8-Chloro-Adenosine in Chronic Lymphocytic Leukemia chronic lymphocytic leukemia Adenosine (NPC156461) NP level
NCT01932112 Adenosine Effect on Persistent Pulmonary Vein Isolation Line Evaluation (APPLE Trial) atrial fibrillation Adenosine (NPC156461) NP level

❱❱❱ Associated Human Diseases and Detailed Association Evidence

 How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
 ❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.

Associated Disease of the Plant
Association Type & Detailed Evidence
Adenocarcinoma of pancreas
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C10.0
 ADORA3,ACHE,ADORA2A,CYP2C19,ABCG2
Solid tumour/cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A00-2F9Z
 MKNK2,ADORA2A,MAPK1,ADORA3
Germ cell tumour of testis
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C80.2
 MAPK1,ACHE,ADORA2A,ABCG2
Heart failure
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BD10-BD1Z
 ADORA1,ADORA3,ADORA2A
Parkinsonism
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8A00
 ADORA1,ADORA2A,ACHE
Glaucoma
Disease Category: 09.Diseases of the visual system
Disease ICD-11 Code: 9C61
 ADORA1,ACHE,ADORA2A
Pain, unspecified
Disease Category: 21.Symptoms, signs or clinical findings, not elsewhere classified
Disease ICD-11 Code: MG3Z
 ACHE
 NCT00298636,NCT00349921
coronary artery disease
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA8Y-BA8Z
 NCT01690884,NCT03236311,NCT01593644
Pheochromocytoma
Disease Category: X.Extension Codes
Disease ICD-11 Code: XH3854
 ADORA2A,ACHE,ADORA1
Other specified malignant neoplasms of kidney, except renal pelvis
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C90.Y
 ADORA3,ACHE,ADORA3
Melanoma of skin
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C30
 ADORA2A,ADORA3,ABCG2
Cytomegaloviral disease
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1D82
 ADORA2A,ACHE,CYP2C19
Malignant neoplasms of thymus
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C27
 ADORA2A,ADORA3,ACHE
Rheumatoid arthritis
Disease Category: 15.Diseases of the musculoskeletal system or connective tissue
Disease ICD-11 Code: FA20
 ABCG2,ADORA3
Orthostatic hypotension
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA21
 ADORA1,ADORA2A
Colorectal cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2B91
 ADORA2A,MKNK2
Mild neurocognitive disorder
Disease Category: 06.Mental, behavioural or neurodevelopmental disorders
Disease ICD-11 Code: 6D71
 ADORA1,ACHE
Liver cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C12
 ADORA3,MKNK2
Hyper-lipoproteinaemia
Disease Category: 05.Endocrine, nutritional or metabolic diseases
Disease ICD-11 Code: 5C80
 ADORA1,ADORA2A
Prostate cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C82
 ADORA2A
 NCT01705652
Acute ST elevation myocardial infarction
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA41.0
 NCT01747174,NCT00284323
Stress-induced cardiomyopathy
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC43.5
 NCT04666454,NCT02867878
Angina pectoris
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA40
 NCT01123525,NCT00751491
Atrial fibrillation
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC81.3
 NCT03032965,NCT01932112
Serous cystadenoma,borderline malignancy of ovary
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C73.4
 ADORA1,ADORA3
Zika virus disease
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1D48
 ADORA2A,ACHE
Leishmaniasis
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1F54
 ADORA2A,ADORA3
Diffuse large B-cell lymphomas
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A81
 ADORA1,ACHE
West Nile virus infection
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1D46
 ADORA2A,ACHE
Hepatocellular carcinoma of liver
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C12.02
 ADORA1,ADORA1
Chronic arterial occlusive disease
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BD4Z
 ADORA2A
Malaria
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1F40-1F45
 ADORA3
Unspecific substance harmful effect
Disease Category: 22.Injury, poisoning or certain other consequences of external causes
Disease ICD-11 Code: NE6Z
 ACHE
Arteries/arterioles disorder
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BD52
 MAPK1
Pulmonary hypertension
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BB01
 ADORA2A
Radionuclide imaging
Disease Category: NA
Disease ICD-11 Code: N.A.
 ADORA2A
Pancreatic cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C10
 MAPK1
Breast cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C60-2C6Y
 MKNK2
Mature T-cell lymphoma
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A90
 MKNK2
Alzheimer disease
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8A20
 ACHE
Parasitic worm infestation
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1F90
 ACHE
Choreiform disorder
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8A01
 ADORA2A
Dementia
Disease Category: 06.Mental, behavioural or neurodevelopmental disorders
Disease ICD-11 Code: 6D80-6D8Z
 ACHE
Lung cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C25
 ADORA2A
Schizophrenia
Disease Category: 06.Mental, behavioural or neurodevelopmental disorders
Disease ICD-11 Code: 6A20
 ADORA2A
Supraventricular tachyarrhythmia
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC81
 ADORA1
Vasomotor/allergic rhinitis
Disease Category: 12.Diseases of the respiratory system
Disease ICD-11 Code: CA08
 ADORA2A
Myasthenia gravis
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8C6Y
 ACHE
Oesophageal/gastroduodenal disorder
Disease Category: 13.Diseases of the digestive system
Disease ICD-11 Code: DD90
 ACHE
Irritable bowel syndrome
Disease Category: 13.Diseases of the digestive system
Disease ICD-11 Code: DD91
 ABCG2
Unspecific substance use disorder
Disease Category: 06.Mental, behavioural or neurodevelopmental disorders
Disease ICD-11 Code: 6C4Z
 ADORA2A
Cardiac arrhythmia
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC9Z
 ADORA1
Pediculosis
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1G00
 ACHE
Substance abuse
Disease Category: 06.Mental, behavioural or neurodevelopmental disorders
Disease ICD-11 Code: 6C40
 ACHE
Psoriasis
Disease Category: 14.Diseases of the skin
Disease ICD-11 Code: EA90
 ADORA3
Diabetic foot ulcer
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BD54
 ADORA2A
Coronary atherosclerosis
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA80
 ADORA2A
Hepatitis virus infection
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1E50-1E51
 ADORA3
Chronic obstructive pulmonary disease
Disease Category: 12.Diseases of the respiratory system
Disease ICD-11 Code: CA22
 ADORA2A
Melanoma
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C30
 MAPK1
Acute respiratory distress syndrome
Disease Category: 12.Diseases of the respiratory system
Disease ICD-11 Code: CB00
 NCT04588441
Neoplasms
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 02
 NCT00845689
Acute myocardial infarction
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA41
 NCT00781404
NA
Disease Category: NA
Disease ICD-11 Code: NA
 NCT00580905
Ischaemic heart diseases, unspecified
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA6Z
 NCT05014061
Chronic lymphocytic leukaemia or small lymphocytic lymphoma
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A82.0
 NCT00714103
Ischemia
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8B10-8B11
 NCT00179010
Ventricular tachycardia
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC71.0
 NCT04392362
Diseases of coronary artery, unspecified
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA8Z
 NCT00612521
Myocardial infarction
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA41-BA43
 NCT00590070
Cardiomyopathy
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC43
 NCT02681913
Central nervous system disease
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8A04-8D87
 NCT01233492
Unspecified malignant neoplasms of unspecified sites
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2D4Z
 NCT00565188
Carcinosarcoma of uterus
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C76.43
 ADORA1
Dengue fever, unspecified
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1D2Z
 ABCG2
Malignant neoplasms of biliary tract, distal bile duct
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C15
 ADORA1
Intrauterine growth restriction
Disease Category: 19.Certain conditions originating in the perinatal period
Disease ICD-11 Code: KA20.1
 ADORA2A
Mesothelioma of pleura
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C26.0
 ADORA3
Pre-eclampsia
Disease Category: 18.Pregnancy, childbirth or the puerperium
Disease ICD-11 Code: JA24
 ADORA2A
Tetralogy of Fallot
Disease Category: 20.Developmental anomalies
Disease ICD-11 Code: LA88.2
 ABCG2
Superficial ovarian endometriosis
Disease Category: 16.Diseases of the genitourinary system
Disease ICD-11 Code: GA10.B4
 ACHE
Malignant neoplasms of oesophagus
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2B70
 ACHE
Chronic rhinosinusitis
Disease Category: 12.Diseases of the respiratory system
Disease ICD-11 Code: CA0A
 ADORA3
Systemic lupus erythematosus
Disease Category: 04.Diseases of the immune system
Disease ICD-11 Code: 4A40.0
 ACHE
Malignant neoplasms of thyroid gland, unspecified
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2D10.Z
 ADORA1
Adenocarcinoma of bronchus or lung
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C25.0
 ACHE
Chikungunya virus disease
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1D40
 ADORA2A
Dilated cardiomyopathy
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC43.0
 ABCG2
Invasive carcinoma of breast
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C61
 ADORA2A
Heart failure, unspecified
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BD1Z
 ABCG2
Human immunodeficiency virus disease without mention of tuberculosis or malaria
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1C62
 ADORA3
Glioblastoma of brain
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A00.00
 ADORA3
Carpal tunnel syndrome
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8C10.0
 ADORA3
Ebola virus disease
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1D60.01
 ACHE
Malignant neoplasms of adrenal gland
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2D11
 ADORA1
Gliomas of brain
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A00.0
 ADORA3

❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations

Plant-Targeted Human Disease Network 
Data Section
Select to Download
1. General Info & Plant Usage & Geographical Distribution  
2. Plant Ingredients  
3. Collective Molecular Proteins  
4. Collective Enriched Activities  
5. Plant molecular targets overlapping with DEGs  
6. Associated clinical trials  
7. Associated Human Diseases  
>> Targets derived from weak experimental activities
About Us

The CMAUP database is developed by the Bioinformatics & Drug Design group (BIDD) and School of Pharmacy, Fudan University.

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Principle Investigator:
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chenyuzong@sz.tsinghua.edu.cn
Prof. Zeng Xian
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Developer & Maintainer:
Ph.D. Student Dongyue Hou
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Mr. Hanbo Lin
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Ms. Yuhan Feng
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