Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC127447 TSHR 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156461 GAPDH 7 Median: 35000000
Range: 35000 to 100000000
IC50 PMID: 7562915
PMID: 7562915
PMID: 7562915
PMID: 7932587
PMID: 7932587
PMID: 7932587
PMID: 9822549
NPC156461 ADORA2B 3 Median: 24000
Range: 24000 to 24000
EC50 PMID: 20541935
PMID: 21388809
PMID: 24164628
NPC156461 SLC29A1 1 17000 IC50 PMID: 23388705
NPC176740 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC176740 EPHX2 1 24300 IC50 PMID: 24679441
NPC176740 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188646 TP53 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188646 ATM 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188646 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188646 KMT2A 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188646 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC236769 ABCC1 1 50000 IC50 PMID: 21354800
NPC236769 ABCB1 1 16000 IC50 PMID: 21354800
NPC270620 ABCC1 1 50000 IC50 PMID: 21354800
NPC278556 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278556 KDM4E 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC310259 KDM4E 2 Median: 33552.05
Range: 31622.8 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC310259 ABCC1 1 26350 IC50 PMID: 23851114
NPC310259 ABCB1 1 23400 IC50 PMID: 23851114
NPC310259 ALDH1A1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156461 MAPK1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC270620 ABCB1 1 13000 IC50 PMID: 21354800