TCM-ID Component

Description of the Component

Component ID	TCMH1652
Latin Name	Paris polyphylla
English Name	rhizome of verticillate paris
Chinese Pinyin Name	Qi Ye Yi Zhi Hua
中文名	七叶一枝花
TCM Properties	Cold,Bitter
TCM Meridians	Liver
Therapeutic Class English	Heat clearence
Therapeutic Class Chinese	清热
Functions	remove heat, counteract toxicity, cause the subsidence of swelling and alleviate pain, and relieve convulsions
Toxicity	Toxic
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID	ITSAH2421-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx2129	Compound Powder of Snake-bile and Fritillary Bulb	复方蛇胆川贝散
TCMFx4649	Ji De Sheng She Yao Tablets	季德胜蛇药片
TCMFx4862	Luo Fu Shan Bai Cao You	罗浮山百草油
TCMF2373	QG Yin Qiao Powder	羌膏银翘汤
TCMF2108	Qi Protection Double Solution Decoction
TCMFx2150	Tumor Removing Decoction	消瘿汤

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT132	BCHE	Butyrylcholinesterase	Hydrolase	P06276
TCMT215	CYP1A1	Cytochrome P450 1A1	Oxidoreductase	P04798
TCMT219	CYP1A2	Cytochrome P450 1A2	Oxidoreductase	P05177
TCMT232	ABCB1	P-glycoprotein 1	Transporter	P08183
TCMT240	AMY1A	Salivary alpha-amylase	Unclassified	P04745
TCMT257	CYP1B1	Cytochrome P450 1B1	Oxidoreductase	Q16678
TCMT63	PPARA	Peroxisome proliferator-activated receptor alpha	Nuclear receptor	Q07869
TCMT64	PPARD	Peroxisome proliferator-activated receptor delta	Nuclear receptor	Q03181
TCMT67	PPARG	Peroxisome proliferator-activated receptor gamma	Nuclear receptor	P37231

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1218	Staphylococcus aureus
TCMT1229	Enterococcus faecalis
TCMT1232	Pseudomonas aeruginosa
TCMT1246	Escherichia coli

Ingredient Structrues

Ingredient ID: TCMC348
Formula: C27H44O7

Common Name	20-Hydroxyecdysone
IUPAC Name	(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
Canonical SMILES	O[C@H]1C[C@@]2(C)[C@@H](C[C@H]1O)C(=O)C=C1[C@@H]2CC[C@]2([C@@]1(O)CC[C@@H]2[C@]([C@@H](CCC(O)(C)C)O)(O)C)C
Standard InCHI	InChI=1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1
Standard InCHIKey	NKDFYOWSKOHCCO-YPVLXUMRSA-N
External Identifiers	ChEMBL [CHEMBL224128]; PubChem [5459840];
Reference of Component-Ingredient Pair	29126784

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1673	Gentiana macrophylla	Qin Jiao	秦艽
TCMH2595	Rhododendron micranthum	Zhao Shan Bai	照山白
TCMH1508	Commiphora myrrha	Mo Yao	没药
TCMH1496	Rhizoma dryopteris crassirhizomae	Mian Ma Guan Zhong	绵马贯众
TCMH281	Dipsacus asper	Chuan Duan	川断
TCMH2576	Paris polyphylla	Zao Xiu	蚤休
TCMH1674	Gentiana straminea	Qin Jiao Hua	秦艽花
TCMH2646	Rhizoma paridis	Chong Lou	重楼
TCMH255	Vigna angularis	Chi Dou	赤豆
TCMH2362	Artemisia lactiflora	Ya Jiao Ai	鸭脚艾
TCMH1102	Tinospora capillipes	Jin Guo Lan	金果榄
TCMH202	Bombyx mori	Can Yong	蚕蛹
TCMH1588	Achyranthes bidentata	Niu Xi	牛膝
TCMH1331	Rhaponticum uniflorum	Lou Lu	漏芦
TCMH1584	Achyranthes bidentata	Niu Teng	牛藤
TCMH75	Bombyx mori	Bai Jiang Can	白僵蚕
TCMH197	Bombyx mori	Can E	蚕蛾
TCMH200	Bombyx mori	Can Jian	蚕茧
TCMH201	Bombyx mori	Can Sha	蚕砂
TCMH1652	Paris polyphylla	Qi Ye Yi Zhi Hua	七叶一枝花
TCMH1507	Commiphora myrrha	Mo Xiang	没香
TCMH2017	Artemisia lactiflora	Si Ji Cai	四季菜

Ingredient ID: TCMC1064
Formula: C16H12O6

Common Name	Diosmetin
IUPAC Name	5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one
Canonical SMILES	COc1ccc(cc1O)c1cc(=O)c2c(o1)cc(cc2O)O
Standard InCHI	InChI=1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
Standard InCHIKey	MBNGWHIJMBWFHU-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL90568]; PubChem [5281612];
Reference of Component-Ingredient Pair	22860452

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH888	Pithecellobium clypearia	Hou Er Huan Jin Gao	猴耳环浸膏
TCMH2506	Ginkgo biloba	Yin Xing Ye	银杏叶
TCMH2372	Bergenia purpurascens	Yan Bai Cai	岩白菜
TCMH1144	Schizonepetae herba	Jing Jie Tan	荆芥炭
TCMH2576	Paris polyphylla	Zao Xiu	蚤休
TCMH370	Herba cirsii japonici	Da Ji(1)	大蓟
TCMH733	Desmodium styracifolium	Guang Jin Qian Cao	广金钱草
TCMH463	Sanguisorba officinalis	Di Yu Tan	地榆炭
TCMH1460	Zanthoxylum nitidum	Mao Liang Mian Zhen	毛两面针
TCMH2642	Gardenia jasminoides	Zhi Zi Jin Gao	栀子浸膏
TCMH1141	Schizonepeta tenuifolia	Jing Jie	荆芥
TCMH226	Camellia sinensis	Cha Ye	茶叶
TCMH1872	Cnidium monnieri	She Ma Zi	蛇麻子
TCMH261	Ericerus pela	Chong Bai La	虫白蜡
TCMH1601	Nelumbo nucifera	Ou Pian	藕片
TCMH2086	Trichosanthes kirilowii	Tian Hua Fen	天花粉
TCMH2297	Cirsium setosum	Xiao Ji	小蓟
TCMH2452	Chrysanthemum indicum	Ye Ju Hua	野菊花
TCMH1503	Eclipta prostrata	Mo Han Lian	墨旱莲
TCMH710	Trichosanthes kirilowii maxim	Gua Lou Zi	瓜蒌子
TCMH348	Lobelia chinensis	Da Ban Bian Lian	大半边莲
TCMH2593	Octopus vulgaris	Zhang Yu	章鱼
TCMH122	Lobelia chinensis	Ban Bian Lian	半边莲
TCMH1866	Cnidium monnieri	She Chuang Zi	蛇床子
TCMH705	Trichosanthes kirilowii	Gua Lou	瓜蒌
TCMH706	Trichosanthes kirilowii	Gua Lou Pi	瓜蒌皮
TCMH707	Trichosanthes kirilowii	Gua Lou Ren	瓜蒌仁
TCMH708	Trichosanthes kirilowii	Gua Lou Ren Shuang	瓜蒌仁霜
TCMH709	Trichosanthes kirilowii	Gua Lou Shi	栝蒌实
TCMH711	Trichosanthes kirilowii	Gua Lou Gen	栝楼根
TCMH712	Trichosanthes kirilowii	Gua Lou Ren(1)	栝楼仁
TCMH368	Herba cirsii japonici	Da Ji Gen	大蓟根
TCMH369	Herba cirsii japonici	Da Ji Gen Jin Gao	大蓟根浸膏
TCMH462	Sanguisorba officinalis	Di Yu	地榆
TCMH60	Ginkgo biloba	Bai Guo	白果
TCMH61	Ginkgo biloba	Bai Guo Ren	白果仁
TCMH1652	Paris polyphylla	Qi Ye Yi Zhi Hua	七叶一枝花
TCMH814	Nelumbo nucifera	He Geng	荷梗
TCMH825	Nelumbo nucifera	He Ye	荷叶
TCMH1275	Nelumbo nucifera	Lian Zi	莲子
TCMH1276	Nelumbo nucifera	Lian Zi Xin	莲子心
TCMH1598	Nelumbo nucifera	Ou	藕
TCMH1599	Nelumbo nucifera	Ou Fen	藕粉
TCMH51	Camellia sinensis	Bai Cha	白茶
TCMH886	Pithecellobium clypearia	Hou Er Huan	猴耳环
TCMH887	Pithecellobium clypearia	Hou Er Huan Gan Jin Gao	猴耳环干浸膏
TCMH1856	Gardenia jasminoides	Shan Zhi	山栀
TCMH2641	Gardenia jasminoides	Zhi Zi	栀子

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC348	C27H44O7	20-Hydroxyecdysone	480.31	-1.1982	3.66	1.049	7	6	138.45	16	4	34	1
TCMC1064	C16H12O6	Diosmetin	300.06	-1.9363	2.56	1.123	1	3	96.22	6	3	22	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Paris polyphylla 七叶一枝花

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC348

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1064

Occurrence of the ingredient across TCM components

Properties

Download Data