Component: Paris polyphylla 蚤休


Description of the Component

Component ID
TCMH2576
Latin Name
Paris polyphylla
English Name
NA
Chinese Pinyin Name
Zao Xiu
中文名
蚤休
TCM Properties
Cold,Bitter
TCM Meridians
Liver
Therapeutic Class English
Heat clearence
Therapeutic Class Chinese
清热
Functions
remove heat, counteract toxicity, cause the subsidence of swelling and alleviate pain, and relieve convulsions
Toxicity
Toxic
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAH2421-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2376 Bone Recovery Decoction 复骨汤
TCMFx2448 Breast Tumor Desolving Decoction 乳腺消瘤汤

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT232 ABCB1 P-glycoprotein 1 Transporter P08183
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1229 Enterococcus faecalis
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli

Ingredient Structrues

Ingredient ID: TCMC348
Formula: C27H44O7

Ingredient ID: TCMC1064
Formula: C16H12O6

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC348 C27H44O7 20-Hydroxyecdysone 480.31 -1.1982 3.66 1.049 7 6 138.45 16 4 34 1
TCMC1064 C16H12O6 Diosmetin 300.06 -1.9363 2.56 1.123 1 3 96.22 6 3 22 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)