TCM Prescription: Gang Tai Shuan



Prescription Description
Prescription IDTCMFx7111
Pinyin NameGang Tai Shuan
Chinese Name肛泰栓
English NameGang Tai Shuan
Function Description凉血止血, 清热解毒, 燥湿敛疮, 消肿止痛。适用于湿热下注所致的内痔, 混合痔的内痔部分Ⅰ, Ⅱ期出现的便血, 肿胀, 疼痛, 以及炎性外痔出现的肛门坠胀疼痛, 水肿, 局部不适。
IndicationsInterior haemorroid disorder
Disease ICD-11 Category SB7B [Interior haemorroid disorder (TM1), 内痔 (TM1) ];
Human Tissues Associated with Indication
ReferenceCFDA
Reference Book/linkhttp://samr.cfda.gov.cn/WS01/CL0001/
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH462 Sanguisorba officinalis 地榆 TCMH462 GENG545-14, GBVT2403-13
TCMH2175 Galla chinensis 五倍子 TCMH2175
TCMH183 Dryobalanops aromatica 冰片 TCMH183 GBVK4926-11
TCMH2402 NA 盐酸小檗碱 TCMH2402
TCMH2405 NA 盐酸罂粟碱 TCMH2405
Reference: CFDA

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT344 AOX1 Aldehyde oxidase Oxidoreductase Q06278
TCMT560 F10 Coagulation factor X Unclassified P00742
TCMT591 ESRRA Estrogen-related receptor alpha Nuclear receptor P11474
TCMT636 POLA1 DNA polymerase alpha subunit Transferase P09884
TCMT644 HTR3A Serotonin 3a (5-HT3a) receptor Ion channel P46098
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT822 FUT7 Alpha-(1,3)-fucosyltransferase 7 Transferase Q11130
TCMT910 ESRRB Estrogen-related receptor beta Nuclear receptor O95718


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1178 Actinomyces viscosus
TCMT1189 Pseudomonas fluorescens
TCMT1208 Escherichia coli K12
TCMT1212 Verticillium dahliae
TCMT1215 Pseudomonas aeruginosa PAO1
TCMT1218 Staphylococcus aureus
TCMT1222 Plasmodium falciparum D6
TCMT1223 Staphylococcus epidermidis
TCMT1229 Enterococcus faecalis
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1255 Human immunodeficiency virus 1
TCMT1294 Human parainfluenza virus 3
TCMT1346 Helicobacter pylori
TCMT1438 Plasmodium falciparum
TCMT1443 Leishmania amazonensis
TCMT1447 Respiratory syncytial virus
TCMT1449 Influenza A virus
TCMT1450 Plasmodium falciparum 3D7
TCMT1463 Mycobacterium tuberculosis
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
Select to Download
1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway