TCM Prescription: She Quan Hua Du Powder



Prescription Description
Prescription IDTCMFx5033
Pinyin NameShe Quan Hua Du San
Chinese Name蛇犬化毒散
English NameShe Quan Hua Du Powder
Function Description毒蛇咬伤, 惊风, 痧病
IndicationsConvulsions, Exanthem
Disease ICD-11 Category 8A68.Z [Type of seizure, unspecified, 癫痫发作类型,未特指的 ];
EA3Z [Unspecified skin disorder attributable to viral infection, 未特指的病毒感染性皮肤病 ];
Human Tissues Associated with IndicationHeart, Brain
ReferenceCFDA
Reference Book/linkhttp://samr.cfda.gov.cn/WS01/CL0001/
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH1573 Bovis calculus 牛黄 TCMH1573
TCMH1613 Sal sedatirum 硼砂 TCMH1613
TCMH2304 Niter 硝石 TCMH2304
TCMH183 Dryobalanops aromatica 冰片 TCMH183 GBVK4926-11
TCMH2605 Margarita 珍珠 TCMH2605
TCMH2329 Realgar 雄黄 TCMH2329
TCMH1337 Calamina 炉甘石 TCMH1337
TCMH1880 Moschus moschiferus 麝香 TCMH1880 GBMA2112-09
Reference: CFDA

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT203 G6PD Glucose-6-phosphate 1-dehydrogenase Oxidoreductase P11413
TCMT230 HSD17B3 Estradiol 17-beta-dehydrogenase 3 Oxidoreductase P37058
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT344 AOX1 Aldehyde oxidase Oxidoreductase Q06278
TCMT591 ESRRA Estrogen-related receptor alpha Nuclear receptor P11474
TCMT807 SLC22A12 Solute carrier family 22 member 12 Transporter Q96S37
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT907 FDPS Farnesyl diphosphate synthase Lyase P14324
TCMT910 ESRRB Estrogen-related receptor beta Nuclear receptor O95718
TCMT974 GPER1 G-protein coupled estrogen receptor 1 GPCR Q99527
TCMT99 SHBG Testis-specific androgen-binding protein Unclassified P04278


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1229 Enterococcus faecalis
TCMT1255 Human immunodeficiency virus 1
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway