Prescription ID | TCMFx4975 |
Pinyin Name | San Huang Wan |
Chinese Name | 三黄丸 |
English Name | San Huang Pills |
Function Description | 痢疾, 吐血, 鼻衄, 咯血, 便秘, 疮疡 |
Indications | Dysentery disorder, Constipation disorder, Constipation, Hemoptysis, Dysentery, Hematemesis |
Disease ICD-11 Category |
SA56 [Dysentery disorder (TM1), 痢疾 (TM1)
]; SA57 [Constipation disorder (TM1), 便秘 (TM1) ]; ME05.0 [Constipation, 便秘 ]; MD22 [Haemoptysis, 咯血 ]; 1A40.Z [Infectious gastroenteritis or colitis without specification of infectious agent, 未特指感染性病原体的感染性胃肠炎或结肠炎 ]; ME24.A5 [Haematemesis, 呕血 ]; |
Human Tissues Associated with Indication | Stomach, Large Intestine |
Reference | CFDA |
Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
---|---|---|---|---|
TCMH972 | Coptis chinensis | 黄连 | TCMH972 | ITSAO4469-14 |
TCMH952 | Penthorum chinense | 黄草 | TCMH952 | GBVJ1979-11 |
TCMH363 | Rheum officinale | 大黄 | TCMH363 | ITSAJ4685-14 |
Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
TCMT114 | CNR2 | Cannabinoid CB2 receptor | GPCR | P34972 |
TCMT115 | CNR1 | Cannabinoid CB1 receptor | GPCR | P21554 |
TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
TCMT160 | HTR7 | Serotonin 7 (5-HT7) receptor | GPCR | P34969 |
TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
TCMT164 | PTGS1 | Cyclooxygenase-1 | Oxidoreductase | P23219 |
TCMT174 | HSD11B1 | 11-beta-hydroxysteroid dehydrogenase 1 | Oxidoreductase | P28845 |
TCMT209 | HSD11B2 | 11-beta-hydroxysteroid dehydrogenase 2 | Oxidoreductase | P80365 |
TCMT215 | CYP1A1 | Cytochrome P450 1A1 | Oxidoreductase | P04798 |
TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
TCMT23 | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | Hydrolase | P05186 |
TCMT257 | CYP1B1 | Cytochrome P450 1B1 | Oxidoreductase | Q16678 |
TCMT27 | DRD1 | Dopamine D1 receptor | GPCR | P21728 |
TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
TCMT3 | ALOX15 | Arachidonate 15-lipoxygenase | Oxidoreductase | P16050 |
TCMT30 | PTGS2 | Cyclooxygenase-2 | Oxidoreductase | P35354 |
TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
TCMT313 | HTR2B | Serotonin 2b (5-HT2b) receptor | GPCR | P41595 |
TCMT314 | HTR2C | Serotonin 2c (5-HT2c) receptor | GPCR | P28335 |
TCMT315 | HTR6 | Serotonin 6 (5-HT6) receptor | GPCR | P50406 |
TCMT318 | HKDC1 | Putative hexokinase HKDC1 | Transferase | Q2TB90 |
TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
TCMT329 | NQO2 | Quinone reductase 2 | Oxidoreductase | P16083 |
TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
TCMT36 | HTR1A | Serotonin 1a (5-HT1a) receptor | GPCR | P08908 |
TCMT37 | HTR2A | Serotonin 2a (5-HT2a) receptor | GPCR | P28223 |
TCMT384 | GRK6 | G protein-coupled receptor kinase 6 | Kinase | P43250 |
TCMT46 | F3 | Coagulation factor III | Unclassified | P13726 |
TCMT47 | BCL2 | Apoptosis regulator Bcl-2 | Ion channel | P10415 |
TCMT508 | SYK | Tyrosine-protein kinase SYK | Kinase | P43405 |
TCMT599 | UBE2N | Ubiquitin-conjugating enzyme E2 N | Transferase | P61088 |
TCMT645 | HTR1E | Serotonin 1e (5-HT1e) receptor | GPCR | P28566 |
TCMT646 | HTR5A | Serotonin 5a (5-HT5a) receptor | GPCR | P47898 |
TCMT729 | PIK3CA | PI3-kinase p110-alpha subunit | Transferase | P42336 |
TCMT730 | PIK3CB | PI3-kinase p110-beta subunit | Transferase | P42338 |
TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
TCMT815 | HTR1D | Serotonin 1d (5-HT1d) receptor | GPCR | P28221 |
TCMT816 | HTR1B | Serotonin 1b (5-HT1b) receptor | GPCR | P28222 |
TCMT817 | HTR4 | Serotonin 4 (5-HT4) receptor | GPCR | Q13639 |
TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
TCMT822 | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Transferase | Q11130 |
Target ID | Target Name |
---|---|
TCMT1170 | Enterobacter cloacae |
TCMT1175 | Human immunodeficiency virus |
TCMT1176 | Streptococcus pneumoniae |
TCMT1178 | Actinomyces viscosus |
TCMT1182 | Streptococcus sanguinis |
TCMT1183 | Candida albicans SC5314 |
TCMT1189 | Pseudomonas fluorescens |
TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
TCMT1201 | Staphylococcus epidermidis ATCC 12228 |
TCMT1212 | Verticillium dahliae |
TCMT1213 | Neisseria gonorrhoeae |
TCMT1218 | Staphylococcus aureus |
TCMT1219 | Enterococcus |
TCMT1222 | Plasmodium falciparum D6 |
TCMT1223 | Staphylococcus epidermidis |
TCMT1226 | Klebsiella pneumoniae |
TCMT1229 | Enterococcus faecalis |
TCMT1230 | Human herpesvirus 5 |
TCMT1232 | Pseudomonas aeruginosa |
TCMT1236 | Mycobacterium bovis |
TCMT1246 | Escherichia coli |
TCMT1249 | Dengue virus 2 |
TCMT1251 | Candida albicans |
TCMT1253 | Penicillium chrysogenum |
TCMT1255 | Human immunodeficiency virus 1 |
TCMT1286 | Bacillus cereus |
TCMT1289 | Shigella dysenteriae |
TCMT1305 | Salmonella enteritidis |
TCMT1318 | Human T-lymphotropic virus 1 |
TCMT1346 | Helicobacter pylori |
TCMT1353 | Plasmodium yoelii |
TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
TCMT1385 | Candida shehatae |
TCMT1438 | Plasmodium falciparum |
TCMT1439 | Mycobacterium smegmatis |
TCMT1442 | Leishmania donovani |
TCMT1454 | Bacillus subtilis |
TCMT1455 | Mycobacterium tuberculosis H37Rv |
TCMT1458 | Filobasidiella neoformans |
TCMT1460 | Mycobacterium intracellulare |
TCMT1462 | Streptococcus mutans |
TCMT1463 | Mycobacterium tuberculosis |
TCMT1464 | Hepatitis B virus |
TCMT1465 | Entamoeba histolytica |
GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
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KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
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