Prescription Description
| Prescription ID | TCMFx4896 |
| Pinyin Name | Luo Han Guo Zhi Ke Tang Jiang |
| Chinese Name | 罗汉果止咳糖浆 |
| English Name | Luo Han Guo Zhi Ke Syrup |
| Function Description | 咳嗽 |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | Lung |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1370 | Siraitia grosvenorii | 罗汉果 | TCMH1370 | ITSAL2179-14 |
| TCMH1617 | Eriobotrya japonica thunb | 枇杷叶 | TCMH1617 | ITSAN1970-14 |
| TCMH2629 | Cortex mori radicis praeparata | 桑白皮 | TCMH2629 | |
| TCMH98 | Cynanchum stauntonii | 白前 | TCMH98 | GQ434571 |
| TCMH46 | Stemona tuberosa | 百部 | TCMH46 | GBVC4204-11, GBVC4202-11 |
| TCMH1080 | Platycodon grandiflorum | 桔梗 | TCMH1080 | ITSAJ4293-14 |
| TCMH191 | Mentha haplocalyx | 薄荷油 | TCMH191 | HM595443 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT190 | PTPN2 | T-cell protein-tyrosine phosphatase | Hydrolase | P17706 |
| TCMT261 | DAPK1 | Death-associated protein kinase 1 | Kinase | P53355 |
| TCMT280 | AKR1B10 | Aldo-keto reductase family 1 member B10 | Oxidoreductase | O60218 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT563 | CDC25B | Dual specificity phosphatase Cdc25B | Hydrolase | P30305 |
| TCMT614 | EGLN1 | Egl nine homolog 1 | Oxidoreductase | Q9GZT9 |
| TCMT807 | SLC22A12 | Solute carrier family 22 member 12 | Transporter | Q96S37 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1178 | Actinomyces viscosus |
| TCMT1214 | Enterococcus faecium |
| TCMT1218 | Staphylococcus aureus |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1229 | Enterococcus faecalis |
| TCMT1246 | Escherichia coli |
| TCMT1248 | Hepatitis C virus |
| TCMT1251 | Candida albicans |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1310 | Enterococcus hirae |
| TCMT1354 | Streptococcus mutans UA159 |
| TCMT1355 | Rhodococcus equi |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1438 | Plasmodium falciparum |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1448 | Enterobacter aerogenes |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples