Prescription Description
| Prescription ID | TCMFx285 |
| Pinyin Name | Xiao Er Fu Qi Zhi Xie San |
| Chinese Name | 小儿敷脐止泻散 |
| English Name | Xiao Er Fu Qi Zhi Xie Powder |
| Function Description | 中寒, 腹泻, 腹痛 |
| Indications | Abdominal pain disorder, Diarrhea |
| Disease ICD-11 Category |
SA58 [Abdominal pain disorder (TM1), 腹痛 (TM1)
]; ME05.1 [Diarrhoea, 腹泻 ]; |
| Human Tissues Associated with Indication | Intestine, Stomach |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH839 | Piper nigrum | 黑胡椒 | TCMH839 | ITSAA3189-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT114 | CNR2 | Cannabinoid CB2 receptor | GPCR | P34972 |
| TCMT232 | ABCB1 | P-glycoprotein 1 | Transporter | P08183 |
| TCMT241 | CHRNA7 | Neuronal acetylcholine receptor protein alpha-7 subunit | Ion channel | P36544 |
| TCMT297 | FABP4 | Fatty acid binding protein adipocyte | Unclassified | P15090 |
| TCMT298 | FABP3 | Fatty acid binding protein muscle | Hydrolase | P05413 |
| TCMT307 | KCNH2 | HERG | Ion channel | Q12809 |
| TCMT314 | HTR2C | Serotonin 2c (5-HT2c) receptor | GPCR | P28335 |
| TCMT552 | CHRNA3 | Neuronal acetylcholine receptor subunit alpha-3 | Ion channel | P32297 |
| TCMT559 | ADRB2 | Beta-2 adrenergic receptor | GPCR | P07550 |
| TCMT629 | ABCC1 | Multidrug resistance-associated protein 1 | Transporter | P33527 |
| TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
| TCMT642 | ADRA1D | Alpha-1d adrenergic receptor | GPCR | P25100 |
| TCMT643 | ADRA1A | Alpha-1a adrenergic receptor | GPCR | P35348 |
| TCMT650 | ADRA1B | Alpha-1b adrenergic receptor | GPCR | P35368 |
| TCMT808 | FABP5 | Fatty acid binding protein epidermal | Unclassified | Q01469 |
| TCMT809 | FABP2 | Fatty acid binding protein intestinal | Unclassified | P12104 |
| TCMT810 | TLR2 | Toll-like receptor 2 | Unclassified | O60603 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1218 | Staphylococcus aureus |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1289 | Shigella dysenteriae |
| TCMT1361 | Neisseria meningitidis |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1393 | Vibrio sp. |
| TCMT1438 | Plasmodium falciparum |
| TCMT1442 | Leishmania donovani |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples