Prescription Description
| Prescription ID | TCMFx1643 |
| Pinyin Name | Bai Tou Weng Tang |
| Chinese Name | 白头翁汤 |
| English Name | Decoction of Pulsatillae |
| Function Description | |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | |
| Reference | Chinese Classical Prescriptions |
| Reference Book/link | ISBN 7-5023-3930-2 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH109 | Pulsatilla chinensis | 白头翁 | TCMH109 | ITSAJ4425-14 |
| TCMH972 | Coptis chinensis | 黄连 | TCMH972 | ITSAO4469-14 |
| TCMH949 | Phellodendron amurense | 黄柏 | TCMH949 | ITSAM1586-14 |
| TCMH1672 | Cortex fraxini | 秦皮 | TCMH1672 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT27 | DRD1 | Dopamine D1 receptor | GPCR | P21728 |
| TCMT287 | TAS2R31 | Taste receptor type 2 member 31 | GPCR | P59538 |
| TCMT303 | KCNA3 | Voltage-gated potassium channel subunit Kv1.3 | Ion channel | P22001 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT38 | DRD2 | Dopamine D2 receptor | GPCR | P14416 |
| TCMT46 | F3 | Coagulation factor III | Unclassified | P13726 |
| TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
| TCMT747 | ABCG2 | ATP-binding cassette sub-family G member 2 | Transporter | Q9UNQ0 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1172 | Staphylococcus aureus subsp. aureus RN4220 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1209 | Staphylococcus haemolyticus |
| TCMT1218 | Staphylococcus aureus |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1230 | Human herpesvirus 5 |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1236 | Mycobacterium bovis |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1286 | Bacillus cereus |
| TCMT1289 | Shigella dysenteriae |
| TCMT1305 | Salmonella enteritidis |
| TCMT1318 | Human T-lymphotropic virus 1 |
| TCMT1321 | Staphylococcus hominis |
| TCMT1343 | Staphylococcus simulans |
| TCMT1344 | Staphylococcus sciuri |
| TCMT1345 | Prevotella loescheii |
| TCMT1346 | Helicobacter pylori |
| TCMT1353 | Plasmodium yoelii |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1385 | Candida shehatae |
| TCMT1438 | Plasmodium falciparum |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1442 | Leishmania donovani |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1460 | Mycobacterium intracellulare |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1464 | Hepatitis B virus |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples