Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC2152	TCMT112	Adenosine A3 receptor	Homo sapiens	Ki: 3370 (nM), Ref: 8576921
TCMC2013	TCMT223	Aldose reductase	Homo sapiens	IC50: 2700 (nM), Ref: 22261024
TCMC870	TCMT303	Voltage-gated potassium channel subunit Kv1.3	Homo sapiens	IC50: 740 (nM), Ref: 20971642 IC50: 2 (nM), Ref: 20971642
TCMC2198	TCMT311	Multidrug and toxin extrusion protein 1	Homo sapiens	IC50: 9400 (nM), Ref: 23241029
TCMC1188	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 9730 (nM), Ref: 22892213
TCMC1188	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7700 (nM), Ref: 22892213
TCMC1188	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 4860 (nM), Ref: 22892213
TCMC1188	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4320 (nM), Ref: 22892213
TCMC1188	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 610 (nM), Ref: 22892213
TCMC1871	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9200 (nM), Ref: 20185318 Ki: 9200 (nM), Ref: 20590092 Ki: 9200 (nM), Ref: 20674354 Ki: 9200 (nM), Ref: 21282059 Ki: 9200 (nM), Ref: 23265898 Ki: 9200 (nM), Ref: 23010455 Ki: 9200 (nM), Ref: 24189056
TCMC1871	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8800 (nM), Ref: 20185318 Ki: 8800 (nM), Ref: 20590092 Ki: 8800 (nM), Ref: 20674354 Ki: 8800 (nM), Ref: 21282059 Ki: 8800 (nM), Ref: 23265898 Ki: 8800 (nM), Ref: 23010455 Ki: 8800 (nM), Ref: 24189056 Ki: 8800 (nM), Ref: 26520662
TCMC1871	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9500 (nM), Ref: 20185318 Ki: 9500 (nM), Ref: 20590092 Ki: 9500 (nM), Ref: 20674354 Ki: 9500 (nM), Ref: 23010455
TCMC1871	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 2700 (nM), Ref: 20185318 Ki: 2700 (nM), Ref: 20590092 Ki: 2700 (nM), Ref: 20674354 Ki: 2700 (nM), Ref: 23010455
TCMC1871	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 5500 (nM), Ref: 20185318 Ki: 5500 (nM), Ref: 20590092 Ki: 5500 (nM), Ref: 20674354 Ki: 5500 (nM), Ref: 21282059 Ki: 5500 (nM), Ref: 21332115 Ki: 5500 (nM), Ref: 23265898 Ki: 5500 (nM), Ref: 23265903 Ki: 5500 (nM), Ref: 23010455 Ki: 5500 (nM), Ref: 24189056 Ki: 5500 (nM), Ref: 26073005 Ki: 5500 (nM), Ref: 26520662
TCMC2188	TCMT223	Aldose reductase	Homo sapiens	IC50: 2030 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1424	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2100 (nM), Ref: 17994701
TCMC315	TCMT46	Coagulation factor III	Homo sapiens	IC50: 14.98 (nM), Ref: 23199480
TCMC2150	TCMT46	Coagulation factor III	Homo sapiens	IC50: 22.78 (nM), Ref: 23199480
TCMC2150	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 231 (nM), Ref: 23332346
TCMC1191	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 9800 (nM), Ref: 22892213
TCMC1191	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7450 (nM), Ref: 22892213
TCMC1191	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 5040 (nM), Ref: 22892213
TCMC1191	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3870 (nM), Ref: 22892213
TCMC1191	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 370 (nM), Ref: 22892213
TCMC858	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 66 (nM), Ref: 23332346
TCMC858	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 119 (nM), Ref: 23332346
TCMC2036	TCMT287	Taste receptor type 2 member 31	Homo sapiens	IC50: 3600 (nM), Ref: 21650152
TCMC1869	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 4410 (nM), Ref: 15658857
TCMC2010	TCMT747	ATP-binding cassette sub-family G member 2	Homo sapiens	IC50: 570 (nM), Ref: 23851114 IC50: 540 (nM), Ref: 23851114
TCMC1878	TCMT82	Estrogen receptor alpha	Homo sapiens	IC50: 300 (nM), Ref: 24200808
TCMC1898	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 7906 (nM), Ref: 20696580
TCMC1898	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 1679 (nM), Ref: 20696580
TCMC1898	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 1491 (nM), Ref: 20696580
TCMC1898	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 900 (nM), Ref: 10.1039/C3MD00166K
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC313	TCMT46	Coagulation factor III	Homo sapiens	IC50: 187.26 (nM), Ref: 23199480
TCMC2151	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 443 (nM), Ref: 23332346
TCMC785	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 610 (nM), Ref: 23062825
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1828	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 900 (nM), Ref: 17994701
TCMC1852	TCMT747	ATP-binding cassette sub-family G member 2	Homo sapiens	IC50: 1880 (nM), Ref: 23851114 IC50: 822 (nM), Ref: 23851114
TCMC2146	TCMT46	Coagulation factor III	Homo sapiens	IC50: 8.35 (nM), Ref: 23199480
TCMC784	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 100 (nM), Ref: 26003344
TCMC784	TCMT132	Butyrylcholinesterase	Homo sapiens	IC50: 1090 (nM), Ref: 26003344
TCMC423	TCMT112	Adenosine A3 receptor	Homo sapiens	Ki: 1210 (nM), Ref: 8576921

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC870	TCMT1107	Protease	Human immunodeficiency virus 1	IC50: 31 (ug/ml), Ref: 17112640
TCMC1425	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 71 (ug/ml), Ref: 1710653 IC50: 71 (ug/ml), Ref: 21295891
TCMC1866	TCMT1112	Quinolone resistance protein norA	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC785	TCMT1104	Sortase	Staphylococcus aureus	IC50: 8.7 (ug/ml), Ref: 17716892 IC50: 8.7 (ug/ml), Ref: 19269184
TCMC785	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 100 (ug/ml), Ref: 1710653 IC50: 100 (ug/ml), Ref: 21295891
TCMC785	TCMT1154	Sortase	Staphylococcus aureus	IC50: 40.6 (ug/ml), Ref: 26551342
TCMC1491	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 0.00423 (ug/ml), Ref: 21334901 IC50: 0.00211 (ug/ml), Ref: 21334901
TCMC2013	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812
TCMC1019	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 4 (ug/ml), Ref: 23369537
TCMC2383	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.96 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2398	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.557 (ug/ml), Ref: 3286870 IC50: 2.008 (ug/ml), Ref: 3286870
TCMC2402	TCMT1251	Candida albicans	Candida albicans	MIC: 31.25 (ug/ml), Ref: 8254344
TCMC2407	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.5 (ug/ml), Ref: 19651906
TCMC2407	TCMT1321	Staphylococcus hominis	Staphylococcus hominis	MIC: 0.125 (ug/ml), Ref: 19651906 MIC: 0.063 (ug/ml), Ref: 19651906
TCMC2407	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 0.125 (ug/ml), Ref: 19651906 MIC: 0.063 (ug/ml), Ref: 19651906
TCMC2407	TCMT1209	Staphylococcus haemolyticus	Staphylococcus haemolyticus	MIC: 0.125 (ug/ml), Ref: 19651906 MIC: 0.063 (ug/ml), Ref: 19651906
TCMC2407	TCMT1343	Staphylococcus simulans	Staphylococcus simulans	MIC: 0.125 (ug/ml), Ref: 19651906 MIC: 0.063 (ug/ml), Ref: 19651906
TCMC2407	TCMT1344	Staphylococcus sciuri	Staphylococcus sciuri	MIC: 0.125 (ug/ml), Ref: 19651906 MIC: 0.063 (ug/ml), Ref: 19651906
TCMC2407	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 4 (ug/ml), Ref: 19651906
TCMC2407	TCMT1345	Prevotella loescheii	Prevotella loescheii	MIC: 4 (ug/ml), Ref: 19651906
TCMC1424	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 27.95 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2237	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4 (ug/ml), Ref: 24549242
TCMC1210	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 30 (ug/ml), Ref: 18564877
TCMC2428	TCMT1251	Candida albicans	Candida albicans	MIC: 16 (ug/ml), Ref: 8699187
TCMC2428	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 8 (ug/ml), Ref: 8699187
TCMC2442	TCMT1251	Candida albicans	Candida albicans	MIC: 50 (ug/ml), Ref: 10924184
TCMC2442	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 50 (ug/ml), Ref: 10924184
TCMC2442	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 10924184
TCMC2442	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10924184
TCMC2479	TCMT1251	Candida albicans	Candida albicans	MIC: 6.25 (ug/ml), Ref: 11170676
TCMC2479	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 25 (ug/ml), Ref: 11170676
TCMC2506	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.99 (ug/ml), Ref: 8786363 IC50: 1.9 (ug/ml), Ref: 8786363
TCMC2506	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.99 (ug/ml), Ref: 8786363 IC50: 1.9 (ug/ml), Ref: 8786363
TCMC1425	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.422 (ug/ml), Ref: 3286870 IC50: 1.607 (ug/ml), Ref: 3286870
TCMC934	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.73 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC858	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.555 (ug/ml), Ref: 3286870 IC50: 1.739 (ug/ml), Ref: 3286870
TCMC858	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 42.71 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1898	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 12.5 (ug/ml), Ref: 22280816
TCMC1898	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 80.76 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1898	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 73 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 63.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC2618	TCMT1172	Staphylococcus aureus subsp. aureus RN4220	Staphylococcus aureus subsp. aureus RN4220	MIC: 16 (ug/ml), Ref: 23994872
TCMC2618	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 16 (ug/ml), Ref: 23994872
TCMC909	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 11170636
TCMC865	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.238 (ug/ml), Ref: 14575431
TCMC865	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 23 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC865	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 7.81 (ug/ml), Ref: 26681509
TCMC865	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 31.25 (ug/ml), Ref: 26681509
TCMC2086	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 100 (ug/ml), Ref: 10924184
TCMC2086	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10924184
TCMC785	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.36 (ug/ml), Ref: 10.1016/S0960-894X(00)80357-1 IC50: 0.141 (ug/ml), Ref: 3286870 IC50: 0.148 (ug/ml), Ref: 3286870
TCMC785	TCMT1246	Escherichia coli	Escherichia coli	MIC: 5 (ug/ml), Ref: 16359864 MIC: 31.25 (ug/ml), Ref: 18591276
TCMC785	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 64 (ug/ml), Ref: 16730982 MIC: 31.3 (ug/ml), Ref: 16872133
TCMC785	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 17716892 MIC: 50 (ug/ml), Ref: 9784149 MIC: 60 (ug/ml), Ref: 15568768 MBC: 64 (ug/ml), Ref: 10.1007/s00044-013-0844-5 MIC: 32 (ug/ml), Ref: 10.1007/s00044-013-0844-5
TCMC785	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 100 (ug/ml), Ref: 9784149
TCMC785	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 25 (ug/ml), Ref: 9784149
TCMC785	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 9784149 MIC: 31.3 (ug/ml), Ref: 16872133 MIC: 15.6 (ug/ml), Ref: 16872133
TCMC785	TCMT1385	Candida shehatae	Candida shehatae	MIC: 7.8 (ug/ml), Ref: 16872133
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC1491	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 0.92 (ug/ml), Ref: 21334901
TCMC1491	TCMT1318	Human T-lymphotropic virus 1	Human T-lymphotropic virus 1	IC50: 1.07 (ug/ml), Ref: 21334901
TCMC1828	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.281 (ug/ml), Ref: 3286870 IC50: 0.163 (ug/ml), Ref: 3286870
TCMC784	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2811	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.35 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1047	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 50 (nM), Ref: 24549242