Prescription Description
| Prescription ID | TCMFx1036 |
| Pinyin Name | Zi Jin Ding |
| Chinese Name | ç´«é‡‘é” |
| English Name | Zi Jin Tincture |
| Function Description | éœä¹±ç—§èƒ€, 暑湿温疫, é¢ ç‹‚æ˜ä¹±, 五ç», 暴厥, 岚瘴ä¸æ¶, 水土ä¸æœ, 喉风, ä¸æ¯’, 鬼胎, 痈疽, 蛇犬诸伤 |
| Indications | Dampness and warmth disorder, Severe vomiting and diarrhoea disorder |
| Disease ICD-11 Category |
SE02 [Dampness and warmth disorder (TM1), 湿温 (TM1)
]; SD92 [Severe vomiting and diarrhoea disorder (TM1), éœä¹± (TM1) ]; |
| Human Tissues Associated with Indication | Skin |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1659 | Semen euphorbiae pulveratum | åƒé‡‘å霜 | TCMH1659 | ITSAM343-14 |
| TCMH857 | Radix knoxiae | 红大戟 | TCMH857 | |
| TCMH1813 | Asarum sagittarioides | å±±æ…ˆè‡ | TCMH1813 | ITSAI1567-14 |
| TCMH1717 | Moschus moschiferus | 人工éºé¦™ | TCMH1717 | GBMA2112-09 |
| TCMH2329 | Realgar | 雄黄 | TCMH2329 | |
| TCMH2175 | Galla chinensis | 五å€å | TCMH2175 | |
| TCMH2682 | Cinnabaris | æœ±ç ‚ | TCMH2682 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT187 | AR | Androgen Receptor | Nuclear receptor | P10275 |
| TCMT203 | G6PD | Glucose-6-phosphate 1-dehydrogenase | Oxidoreductase | P11413 |
| TCMT230 | HSD17B3 | Estradiol 17-beta-dehydrogenase 3 | Oxidoreductase | P37058 |
| TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
| TCMT261 | DAPK1 | Death-associated protein kinase 1 | Kinase | P53355 |
| TCMT344 | AOX1 | Aldehyde oxidase | Oxidoreductase | Q06278 |
| TCMT591 | ESRRA | Estrogen-related receptor alpha | Nuclear receptor | P11474 |
| TCMT636 | POLA1 | DNA polymerase alpha subunit | Transferase | P09884 |
| TCMT807 | SLC22A12 | Solute carrier family 22 member 12 | Transporter | Q96S37 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT822 | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Transferase | Q11130 |
| TCMT910 | ESRRB | Estrogen-related receptor beta | Nuclear receptor | O95718 |
| TCMT974 | GPER1 | G-protein coupled estrogen receptor 1 | GPCR | Q99527 |
| TCMT99 | SHBG | Testis-specific androgen-binding protein | Unclassified | P04278 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1438 | Plasmodium falciparum |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples