Prescription Description
| Prescription ID | TCMF6984 |
| Pinyin Name | Qin Huang Hou Zheng Jiao Nang |
| Chinese Name | 芩黄喉症胶囊 |
| English Name | Qin Huang Hou Zheng Capsules |
| Function Description | 清热解毒, 消肿止痛。用于热毒内盛所致的咽喉肿痛。 |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | Lung |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH972 | Coptis chinensis | 黄连 | TCMH972 | ITSAO4469-14 |
| TCMH1716 | Calculus bovis artificiosus | 人工牛黄 | TCMH1716 | |
| TCMH2641 | Gardenia jasminoides | 栀子 | TCMH2641 | ITSAJ4473-14 |
| TCMH2532 | Curcuma aromatica | 郁金 | TCMH2532 | ITSAF2298-14 |
| TCMH363 | Rheum officinale | 大黄 | TCMH363 | ITSAJ4685-14 |
| TCMH989 | Scutellaria baicalensis | 黄芩浸膏 | TCMH989 | ITSAP4211-14 |
| TCMH183 | Dryobalanops aromatica | 冰片 | TCMH183 | GBVK4926-11 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT114 | CNR2 | Cannabinoid CB2 receptor | GPCR | P34972 |
| TCMT115 | CNR1 | Cannabinoid CB1 receptor | GPCR | P21554 |
| TCMT126 | TERT | Telomerase reverse transcriptase | Transferase | O14746 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
Showing 1 to 10 of 113 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1182 | Streptococcus sanguinis |
| TCMT1183 | Candida albicans SC5314 |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1191 | Bacillus megaterium |
Showing 1 to 10 of 71 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AXL, BCL2, CYP1B1, MMP9, RELA, SRC | 3.16578 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, DNMT1, FABP3, KDR, MMP2, PTGES, PTGS2, RELA, SRC | 3.17896 |
| [BP] GO:0001503 | ossification | ALOX15, ALPL, BCL2, MMP2, MMP9 | 2.20561 |
| [BP] GO:0001516 | None | PTGES, PTGS1, PTGS2 | 2.85728 |
| [BP] GO:0001662 | None | BCL2, DRD1, HTR1A, HTR2C | 3.22409 |
| [BP] GO:0001666 | response to hypoxia | BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SRC, TERT | 3.0058 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, PTGES, PTGS1, PTGS2 | 5.64259 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ALOX15, APP, AR, BCL2, DRD1, FABP4, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, SRC, XDH | 4.60833 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ALOX15, APP, AR, BCL2, FLT3, HTR2A, HTR2B, HTR2C, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, SRC, XDH | 4.98751 |
| [BP] GO:0002009 | morphogenesis of an epithelium | AR, BCL2, CA2, CA9, ESR1, MET, SRC | 2.0554 |
Showing 1 to 10 of 458 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCB1 | 0.6944 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | MAP2K1, PIK3CA, FLT3, KIT, PIM1, PIK3CB, RELA | 7.1615 |
| Adherens junction_Homo sapiens_hsa04520 | CSNK2A1, SRC, MAP3K7, MET, IGF1R | 4.2203 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA, RELA | 1.3181 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | PIK3CA, BCL2, CACNA1C, PIK3CB | 2.2029 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | PIK3CA, MMP2, BCL2, PIM1, PIK3CB, F3, RELA | 5.7528 |
| Alcoholism_Homo sapiens_hsa05034 | MAP2K1, MAOA, DRD1 | 1.2855 |
| Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | CACNA1C | 0.5058 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2, PIK3CA, PIK3CB | 2.8251 |
| Alzheimer's disease_Homo sapiens_hsa05010 | BACE1, APP, CACNA1C | 1.3372 |
Showing 1 to 10 of 179 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples