GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, HSD11B1, HSD17B2, KIT, MET, PPARA, PTGS2, TRPV1 |
10.8681 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, FABP3, IDO1, PIM1, PPARA, PTGS2, TYR, XDH |
10.8681 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, AKR1C3, ALOX15, APP, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B2, IDO1, IGF1R, KDR, KIT, MMP2, NR3C1, PPARA, PTGS2, SRC, TRPV1, TYR |
10.4625 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, AKR1C3, ALOX15, APP, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B2, IDO1, IGF1R, KDR, KIT, MMP2, MMP9, NR3C1, PPARA, PTGS2, SRC, TOP1, TRPV1, TYR |
10.1471 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, AKR1C3, APP, AXL, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, GSK3B, HSD17B2, IDO1, IGF1R, MMP2, MMP9, NR3C1, PPARA, PTGS2, SRC, TRPV1, TYR |
9.69756 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX12, ALOX15, APP, AURKB, AXL, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, HSD11B1, HSD17B2, KDR, KIT, MET, PPARA, PTGS2, SRC, TRPV1, XDH |
9.63034 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, GSK3B, HSD11B1, HSD17B2, IDO1, PTGS2, TYR, XDH |
9.44126 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, AKR1C3, ALOX15, APP, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, KIT, MMP9, PTGS2, SRC |
9.31897 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9, DHFR |
8.27512 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, APP, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, HSD11B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, NR3C1, PIM1, PPARA, PTGS2, SRC, TOP1, TRPV1, TYR, XDH |
8.15384 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.67787 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, AKR1C3, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, HSD11B1, HSD17B2 |
7.53622 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, TYR |
7.25464 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
AKR1C3, ALOX12, ALOX15, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
7.096 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AKR1C3, ALOX12, AURKB, AXL, CYP1B1, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP9, PIM1, PPARA, PTGS2, SRC, TRPV1, XDH |
6.94467 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
6.94467 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, AKR1C3, APP, CA2, CA9, CYP1A2, FABP3, FLT3, GSK3B, IGF1R, KIT, MMP2, NR3C1, PPARA, PTGS2, SRC, TRPV1 |
6.92361 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, APP, AXL, CYP19A1, CYP1A2, CYP1B1, F10, FABP4, HSD17B2, IDO1, IGF1R, KIT, MET, MMP1, MMP2, MMP9, PIM1, PPARA, PTGS2, SRC, TOP1, TRPV1, TYR |
6.92361 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, AKR1C3, ALOX15, APP, AXL, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, MMP2, MMP9, NR3C1, PTGS2, SRC, TRPV1 |
6.86641 |
[BP] GO:0006690 |
icosanoid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
6.772 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AKR1C3, ALOX12, AURKB, AXL, CYP1B1, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP9, PIM1, PTGS2, SRC, TRPV1, XDH |
6.7359 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, APP, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, TYR |
6.5663 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, AKR1C3, ALOX15, APP, AXL, CYP1A1, CYP1B1, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, MMP2, NR3C1, PTGS2, SRC, TRPV1 |
6.53686 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, ALOX12, AURKB, AXL, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP9, PIM1, PPARA, PTGS2, SRC |
6.27952 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, CYP3A4, HSD11B1, HSD17B2 |
6.27756 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AXL, CA2, CA7, CYP19A1, CYP1B1, F10, FLT3, GSK3B, KDR, KIT, MET, MMP9, PTGS2, SRC, XDH |
6.23199 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, KIT, MET, PPARA, PTGS2 |
6.23199 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AXL, CA2, CA7, CYP19A1, CYP1B1, F10, FLT3, GSK3B, KDR, KIT, MET, MMP9, PTGS2, SRC, XDH |
6.21492 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX12, ALOX15, APP, AURKB, AXL, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, NR3C1, PIM1, PPARA, PTGS2, SRC, TRPV1, XDH |
6.19508 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX12, ALOX15, APP, AURKB, AXL, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, F10, FABP3, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, NR3C1, PIM1, PPARA, PTGS2, SRC, TRPV1, XDH |
6.14437 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX15, APP, AURKB, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, HSD17B2, IDO1, IGF1R, KDR, KIT, MMP2, MMP9, NR3C1, PPARA, PTGS2, SRC, TOP1, TRPV1, TYR |
6.09834 |
[BP] GO:0033993 |
response to lipid
|
AKR1C3, AXL, CA2, CA9, CYP1A1, CYP1A2, FABP3, FLT3, HSD17B2, IDO1, NR3C1, PTGS2, SRC, TYR |
6.03082 |
[BP] GO:0014070 |
response to organic cyclic compound
|
AKR1C3, APP, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, NR3C1, PTGS2, SRC, TRPV1, TYR |
6.01201 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, APP, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, NR3C1, PIM1, PPARA, PTGS2, SRC, TOP1, TYR, XDH |
6.00491 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, AURKB, AXL, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP9, PIM1, PTGS2, SRC |
6.00491 |
[BP] GO:0006631 |
fatty acid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, PPARA, PTGS2 |
5.88759 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, AKR1C3, ALOX15, APP, AURKB, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, MMP2, MMP9, NR3C1, PTGS2, SRC, TRPV1 |
5.8752 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ALOX12, APP, CYP19A1, CYP1B1, F10, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
5.73447 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
5.71287 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
AKR1C3, ALOX12, ALOX15, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
5.66267 |
[BP] GO:0010038 |
response to metal ion
|
AKR1C3, ALOX15, APP, CA2, CYP1A1, CYP1A2, FABP4, KIT, MMP9, PTGS2 |
5.64815 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX12, APP, CYP1B1, FABP3, FLT3, IDO1, IGF1R, KDR, KIT, MMP2, MMP9, PIM1, PTGS2, SRC, XDH |
5.64612 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, AKR1C3, CA2, CA9, CYP1A2, FABP3, FLT3, KIT, NR3C1, PPARA, PTGS2, SRC, TRPV1 |
5.63541 |
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, AKR1C3, ALOX12, ALOX15, CYP19A1, CYP3A4, DHFR, TYR |
5.62064 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, AKR1C3, CYP19A1, CYP3A4, HSD11B1, HSD17B2 |
5.48439 |
[BP] GO:0044283 |
None
|
AKR1B1, AKR1C3, ALOX12, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP3A4, DHFR, IDO1, PTGS2 |
5.48439 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, CYP3A4, HSD17B2 |
5.48439 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ALOX12, APP, CYP19A1, CYP1B1, F10, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
5.48383 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AXL, CYP1B1, F10, FLT3, KDR, KIT, MET, PTGS2, SRC, XDH |
5.47483 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AKR1C3, ALOX12, AURKB, AXL, CYP1B1, FLT3, GSK3B, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, SRC, TRPV1, XDH |
5.43565 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, IDO1, PIM1, PPARA, PTGS2, TYR |
5.27469 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, AKR1C3, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4 |
5.16769 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, AXL, CA9, CYP1A1, CYP1B1, DHFR, FABP3, KDR, NR3C1, PTGS2, SRC, TOP1, TRPV1 |
5.1473 |
[BP] GO:0032787 |
None
|
AKR1C3, ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, IDO1, PPARA, PTGS2 |
5.1473 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ALOX12, APP, CYP19A1, CYP1B1, F10, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
5.09934 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ALOX12, APP, CYP19A1, CYP1B1, F10, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
5.08684 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, FLT3, GSK3B, IGF1R, KDR, KIT, PIM1, SRC |
5.06047 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, AKR1C3, APP, AXL, CYP1B1, GSK3B, IGF1R, MMP2, MMP9, NR3C1, PTGS2, SRC, TRPV1 |
5.04855 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AXL, CA2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, GSK3B, HSD11B1, HSD17B2, KDR, KIT, MMP9, PIM1, PPARA, PTGS2, SRC, TYR |
5.04635 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APP, DHFR, FABP3, FLT3, GSK3B, IGF1R, MMP2, PPARA, PTGS2, SRC, TRPV1, TYR |
5.01245 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AKR1C3, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, GSK3B, IDO1, MMP1, MMP2, MMP9, SRC, XDH |
4.9638 |
[BP] GO:0043436 |
oxoacid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, IDO1, PIM1, PPARA, PTGS2, TYR |
4.80229 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, APP, AURKB, AXL, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, HSD11B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, NR3C1, PIM1, PPARA, PTGS2, SRC, TOP1, TRPV1, TYR, XDH |
4.79904 |
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX12, ALOX15, ALOX5, PTGS2 |
4.77835 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AURKB, AXL, CA2, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP4, FLT3, GSK3B, HSD11B1, HSD17B2, KDR, KIT, MET, MMP2, MMP9, PIM1, PPARA, PTGS2, SRC, TYR |
4.75434 |
[BP] GO:0006082 |
organic acid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, IDO1, PIM1, PPARA, PTGS2, TYR |
4.72727 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA, TRPV1 |
4.71308 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AXL, CYP1B1, F10, FLT3, GSK3B, KDR, KIT, MET, MMP9, PTGS2, SRC, XDH |
4.67553 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APP, DHFR, FABP3, FLT3, GSK3B, IGF1R, MMP2, PPARA, PTGS2, SRC, TRPV1, TYR |
4.67553 |
[BP] GO:0071248 |
cellular response to metal ion
|
AKR1C3, ALOX15, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
4.67553 |
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, AKR1C3, APP, FLT3, GSK3B, IGF1R, KIT, MMP2, NR3C1, PTGS2, SRC, TRPV1 |
4.63978 |
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, AKR1C3, DHFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC |
4.628 |
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, AKR1C3, ALOX12, ALOX15, CYP19A1, CYP1A1, CYP3A4, HSD11B1, HSD17B2, PTGS2 |
4.62588 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ALOX12, ALOX15, APP, AXL, CA2, CA7, CYP19A1, CYP1B1, F10, GSK3B, IGF1R, KDR, KIT, MET, MMP9, PPARA, PTGS2, SRC, TRPV1 |
4.62588 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AXL, CYP1B1, F10, FABP4, FLT3, GSK3B, IDO1, KDR, KIT, MET, MMP2, MMP9, PTGS2, SRC, XDH |
4.59816 |
[BP] GO:0030335 |
positive regulation of cell migration
|
ALOX12, APP, F10, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
4.5342 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AKR1C3, AXL, CA2, CYP19A1, CYP1A1, CYP1A2, FLT3, HSD11B1, HSD17B2, KDR, KIT, PPARA, SRC, TYR |
4.5166 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, AURKB, AXL, GSK3B, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, SRC |
4.5148 |
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX15, APP, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, GSK3B, IDO1, KIT, MMP2, MMP9, PPARA, PTGS2, SRC, TRPV1 |
4.43665 |
[BP] GO:2000147 |
positive regulation of cell motility
|
ALOX12, APP, F10, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
4.40852 |
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APP, FABP3, GSK3B, IGF1R, PPARA, PTGS2, SRC, TRPV1 |
4.37124 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
AKR1C3, APP, CYP1A1, CYP1B1, FLT3, NR3C1, PTGS2, SRC, TRPV1 |
4.35448 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AURKB, AXL, CYP1B1, F10, FLT3, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC, XDH |
4.35389 |
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ALOX12, APP, F10, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
4.313 |
[BP] GO:0071241 |
cellular response to inorganic substance
|
AKR1C3, ALOX15, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
4.30007 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, AKR1C3, CYP1A1, FABP3, FLT3, KIT, PPARA, PTGS2, SRC |
4.24779 |
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
4.23848 |
[BP] GO:2001300 |
lipoxin metabolic process
|
ALOX12, ALOX15, ALOX5 |
4.22628 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AKR1C3, AXL, CYP1B1, MMP9, SRC |
4.22628 |
[BP] GO:0040017 |
positive regulation of locomotion
|
ALOX12, APP, F10, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
4.19909 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, APP, AURKB, AXL, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, HSD11B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, NR3C1, PIM1, PPARA, PTGS2, SRC, TOP1, TRPV1, TYR, XDH |
4.16564 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.1085 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.06524 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, CYP3A4, HSD11B1, HSD17B2 |
4.05393 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, AXL, CYP1B1, KDR, NR3C1, PTGS2, SRC, TRPV1 |
4.04153 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX12, APP, AURKB, AXL, CYP19A1, CYP1B1, DHFR, FABP3, FABP4, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP9, NR3C1, PIM1, PPARA, PTGS2, SRC, TRPV1, XDH |
4.04153 |
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, KIT, PPARA, PTGS2, SRC |
3.93293 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, IDO1 |
3.92665 |
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
3.89869 |
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, AKR1C3, CYP19A1, CYP3A4, HSD11B1, HSD17B2 |
3.8818 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, GSK3B, MET, MMP9, PPARA, SRC |
3.8601 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, AKR1C3, ALOX12, ALOX15, APP, AURKB, AXL, CYP19A1, CYP1B1, DHFR, F10, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP2, MMP9, PPARA, PTGS2, SRC, XDH |
3.8601 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, AKR1C3, CYP19A1, IDO1 |
3.85246 |
[BP] GO:0044598 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.85246 |
[BP] GO:0044597 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.85246 |
[BP] GO:0030638 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.85246 |
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, CA2, CYP1A1, KIT, MMP2, PPARA, PTGS2, SRC, TRPV1, TYR |
3.84395 |
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA, TRPV1 |
3.83533 |
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AKR1C3, AXL, F10, KIT, MET, SRC, XDH |
3.80206 |
[BP] GO:0030647 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.69645 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX12, ALOX15, APP, AURKB, AXL, CYP19A1, CYP1B1, DHFR, FABP3, FABP4, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP9, NR3C1, PIM1, PPARA, PTGS2, SRC, TRPV1, XDH |
3.65901 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.54857 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AURKB, AXL, CA2, CA7, CYP19A1, CYP1B1, F10, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC, XDH |
3.52867 |
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, ALOX12, APP, CYP19A1, DHFR, FABP4, GSK3B, IDO1, IGF1R, MET, MMP2, PPARA, PTGS2, SRC, XDH |
3.51656 |
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, IDO1, KIT, PTGS2 |
3.48868 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, AKR1C3, APP, AXL, CYP1B1, MMP9, PTGS2, SRC |
3.4822 |
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX12, ALOX15, ALOX5, PTGS2 |
3.46944 |
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AKR1C3, AXL, F10, KIT, MET, SRC |
3.46944 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AURKB, AXL, CA2, CA7, CYP19A1, CYP1B1, F10, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC, XDH |
3.45332 |
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC, TOP1 |
3.38361 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, APP, AURKB, AXL, DHFR, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, PTGS2, SRC, TOP1, XDH |
3.31976 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, KIT, MET, MMP2, MMP9, SRC |
3.2549 |
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, SRC |
3.22937 |
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
AKR1C3, CYP1B1, DHFR, PTGS2, TRPV1, XDH |
3.22937 |
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AKR1C3, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, GSK3B, IDO1, XDH |
3.22937 |
[BP] GO:0046394 |
None
|
ALOX12, ALOX15, ALOX5, CYP1A1, DHFR, IDO1, PTGS2 |
3.2009 |
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, ALOX12, APP, AXL, CA12, CA2, CA7, FABP3, FABP4, FLT3, MET, SRC, TRPV1 |
3.2009 |
[BP] GO:0016053 |
None
|
ALOX12, ALOX15, ALOX5, CYP1A1, DHFR, IDO1, PTGS2 |
3.2009 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CYP1B1, FABP4, GSK3B, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, SRC |
3.2009 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AKR1C3, AXL, CYP1B1, MMP9, SRC |
3.17776 |
[BP] GO:0006066 |
None
|
AKR1B1, AKR1B10, AKR1C3, APP, CYP1B1, CYP3A4, DHFR |
3.11378 |
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, CYP1A1, DHFR, PPARA |
3.11232 |
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APP, GSK3B, IGF1R, MMP2, PTGS2, SRC, TRPV1 |
3.10793 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, APP, AURKB, AXL, DHFR, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, PTGS2, SRC, TOP1, XDH |
3.10793 |
[BP] GO:0016488 |
None
|
AKR1B10, AKR1C3 |
3.10793 |
[BP] GO:0016487 |
None
|
AKR1B10, AKR1C3 |
3.10793 |
[BP] GO:0016107 |
None
|
AKR1B10, AKR1C3 |
3.10793 |
[BP] GO:0006714 |
None
|
AKR1B10, AKR1C3 |
3.10793 |
[BP] GO:2001301 |
lipoxin biosynthetic process
|
ALOX12, ALOX15 |
3.10793 |
[BP] GO:2001302 |
lipoxin A4 metabolic process
|
ALOX12, ALOX15 |
3.10793 |
[BP] GO:2001303 |
lipoxin A4 biosynthetic process
|
ALOX12, ALOX15 |
3.10793 |
[BP] GO:0044236 |
multicellular organism metabolic process
|
AKR1C3, MMP1, MMP2, MMP9, TRPV1 |
3.05741 |
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, AKR1C3, AXL, CYP1B1, MMP9, SRC |
2.95 |
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, F10, FLT3, GSK3B, IGF1R, KDR, KIT, MET, SRC, TOP1 |
2.92888 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, CA2, CA7, KIT, PTGS2 |
2.91576 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, CA2, CA7, KIT, PTGS2 |
2.91576 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AKR1C3, ALOX12, FLT3, IGF1R, KDR, KIT, MMP2, MMP9, PIM1, PTGS2 |
2.90361 |
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APP, GSK3B, IGF1R, MMP2, PTGS2, SRC, TRPV1 |
2.88498 |
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, ALOX12, MET, TRPV1 |
2.85168 |
[BP] GO:0046686 |
response to cadmium ion
|
AKR1C3, CYP1A2, KIT, MMP9 |
2.8503 |
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.8503 |
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, PTGS2 |
2.80794 |
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, CA2, CA7, KDR, SRC, TRPV1 |
2.80351 |
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC |
2.74398 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ALOX12, APP, AXL, CA2, CYP1B1, IDO1, KDR, KIT, MET, MMP9, PIM1, PTGS2, SRC, TRPV1 |
2.6935 |
[BP] GO:0048545 |
response to steroid hormone
|
AKR1C3, CA2, FLT3, NR3C1, PTGS2, SRC |
2.6935 |
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AKR1C3, AURKB, CYP1A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, GSK3B, IDO1, SRC, XDH |
2.6935 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.6935 |
[BP] GO:0016095 |
None
|
AKR1B10, AKR1C3 |
2.6935 |
[BP] GO:0043065 |
positive regulation of apoptotic process
|
AKR1C3, CYP1B1, GSK3B, IDO1, MMP9, PTGS2, SRC, TRPV1, XDH |
2.69155 |
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.68017 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.68017 |
[BP] GO:0043068 |
positive regulation of programmed cell death
|
AKR1C3, CYP1B1, GSK3B, IDO1, MMP9, PTGS2, SRC, TRPV1, XDH |
2.6642 |
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX12, ALOX15, APP, AURKB, AXL, CA1, CA12, CA2, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, HSD11B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, NR3C1, PIM1, PPARA, PTGS2, SRC, TOP1, TRPV1, XDH |
2.61819 |
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC, TOP1 |
2.61455 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, CA2, CA7, KDR, PTGS2, SRC, TRPV1 |
2.6141 |
[BP] GO:0022414 |
reproductive process
|
AKR1B1, AKR1C3, APP, AXL, CYP19A1, CYP1A1, HSD17B2, IDO1, KIT, MMP2, MMP9, PTGS2, SRC |
2.61369 |
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, GSK3B, MET, MMP9, PPARA, SRC |
2.61369 |
[BP] GO:0034097 |
response to cytokine
|
ALOX15, AXL, FABP4, FLT3, GSK3B, PTGS2, SRC, TRPV1 |
2.60071 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.5739 |
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, GSK3B, IGF1R, KDR, KIT, MET, MMP1, MMP9, SRC |
2.55672 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B2 |
2.52273 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.52273 |
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, SRC |
2.48045 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, CYP1A1, FLT3, KIT, MET, PIM1, SRC, TYR |
2.46818 |
[BP] GO:0072330 |
monocarboxylic acid biosynthetic process
|
ALOX12, ALOX15, CYP1A1, IDO1, PTGS2 |
2.44978 |
[BP] GO:0071383 |
None
|
AKR1C3, FLT3, NR3C1, SRC |
2.44361 |
[BP] GO:0010942 |
positive regulation of cell death
|
AKR1C3, CYP1B1, GSK3B, IDO1, MMP9, PTGS2, SRC, TRPV1, XDH |
2.44361 |
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, APP, AURKB, AXL, CYP1A1, CYP1A2, CYP3A4, DHFR, F10, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, PIM1, PPARA, PTGS2, SRC, TOP1, TYR, XDH |
2.44361 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.44361 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.44361 |
[BP] GO:0006706 |
steroid catabolic process
|
CYP19A1, CYP1A2, CYP3A4 |
2.44079 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, FLT3, KDR, KIT, SRC, XDH |
2.42969 |
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, MMP2, MMP9, PTGS2 |
2.41482 |
[BP] GO:1904646 |
cellular response to amyloid-beta
|
APP, GSK3B, IGF1R |
2.39886 |
[BP] GO:0046427 |
positive regulation of JAK-STAT cascade
|
AKR1B1, CYP1B1, FLT3, KIT |
2.39886 |
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, FLT3, IGF1R, KDR, KIT, MET, MMP2, MMP9, SRC |
2.39886 |
[BP] GO:0031960 |
response to corticosteroid
|
AKR1C3, FLT3, NR3C1, PTGS2, SRC |
2.388 |
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, CYP1A1, MMP2, PPARA, PTGS2, SRC |
2.36554 |
[BP] GO:1904894 |
positive regulation of STAT cascade
|
AKR1B1, CYP1B1, FLT3, KIT |
2.36337 |
[BP] GO:0070542 |
None
|
AKR1C3, FABP3, PTGS2, SRC |
2.34551 |
[BP] GO:1901570 |
None
|
ALOX12, ALOX15, ALOX5, PTGS2 |
2.34551 |
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX12, ALOX15, PTGS2 |
2.32098 |
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, CYP19A1, CYP1A2, IDO1, XDH |
2.3092 |
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, CYP1A1, MMP2, PPARA, PTGS2, SRC |
2.30468 |
[BP] GO:1901661 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.28655 |
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC |
2.28655 |
[BP] GO:1904645 |
response to amyloid-beta
|
APP, GSK3B, IGF1R |
2.28655 |
[BP] GO:0048608 |
reproductive structure development
|
AKR1C3, AXL, CYP19A1, HSD17B2, KIT, SRC |
2.28652 |
[BP] GO:0061370 |
testosterone biosynthetic process
|
AKR1C3, CYP19A1 |
2.27277 |
[BP] GO:0002318 |
myeloid progenitor cell differentiation
|
FLT3, KIT |
2.27277 |
[BP] GO:0051122 |
hepoxilin biosynthetic process
|
ALOX12, ALOX15 |
2.27277 |
[BP] GO:0051121 |
hepoxilin metabolic process
|
ALOX12, ALOX15 |
2.27277 |
[BP] GO:0071276 |
cellular response to cadmium ion
|
AKR1C3, CYP1A2, MMP9 |
2.2568 |
[BP] GO:0006691 |
None
|
ALOX12, ALOX15, ALOX5 |
2.2568 |
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
AKR1C3, MMP1, MMP2, MMP9 |
2.25187 |
[BP] GO:0032496 |
response to lipopolysaccharide
|
AXL, CYP1A1, CYP1A2, IDO1, PTGS2, SRC |
2.24032 |
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PPARA, PTGS2, SRC, XDH |
2.23638 |
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, FLT3, IGF1R, KDR, KIT, SRC, XDH |
2.23229 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7 |
2.22316 |
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, FABP3, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PPARA, PTGS2, SRC, XDH |
2.22265 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, AKR1C3, ALOX15, APP, AURKB, DHFR, FABP3, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP9, NR3C1, PPARA, PTGS2, SRC, TRPV1, XDH |
2.22265 |
[BP] GO:0044242 |
None
|
AKR1B10, AKR1C3, CYP1B1, FABP3, FABP4 |
2.20959 |
[BP] GO:0048511 |
rhythmic process
|
AXL, GSK3B, KIT, PPARA, SRC, TOP1 |
2.19805 |
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, FABP3, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PPARA, PTGS2, SRC, XDH |
2.19805 |
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC |
2.19805 |
[BP] GO:0001523 |
None
|
AKR1B10, AKR1C3, CYP1A1, CYP1B1 |
2.19805 |
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
AKR1C3, PTGS2, TRPV1, XDH |
2.19805 |
[BP] GO:1904018 |
positive regulation of vasculature development
|
ALOX12, CYP1B1, KDR, KIT, PTGS2 |
2.19805 |
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, FABP3, FLT3, KDR, KIT, MMP9, PTGS2, SRC, XDH |
2.19805 |
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, FABP3, FLT3, KDR, KIT, MMP9, PTGS2, SRC, XDH |
2.19805 |
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, AKR1C3, ALOX15, AXL, CA2, CA9, CYP1B1, DHFR, GSK3B, MMP9, PTGS2, SRC, TRPV1 |
2.19451 |
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, AKR1C3, ALOX15, APP, AURKB, FABP3, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP9, NR3C1, PPARA, PTGS2, SRC, TRPV1, XDH |
2.17295 |
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, CYP1A1, MMP2, PPARA, PTGS2, SRC |
2.15295 |
[BP] GO:0002933 |
lipid hydroxylation
|
CYP1A1, CYP3A4 |
2.14246 |
[BP] GO:0016115 |
None
|
AKR1B10, AKR1C3 |
2.14246 |
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP3A4 |
2.14246 |
[BP] GO:0002237 |
response to molecule of bacterial origin
|
AXL, CYP1A1, CYP1A2, IDO1, PTGS2, SRC |
2.12157 |
[BP] GO:0009991 |
response to extracellular stimulus
|
AKR1C3, AXL, CYP1A1, PTGS2, SRC, TRPV1, TYR |
2.11085 |
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AURKB, AXL, CYP1B1, F10, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC, XDH |
2.10779 |
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, KIT, PTGS2, TRPV1 |
2.09573 |
[BP] GO:0016101 |
None
|
AKR1B10, AKR1C3, CYP1A1, CYP1B1 |
2.09573 |
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, ALOX12, APP, CA12, CA2, CA7, FABP3, FABP4, MET, TRPV1 |
2.08384 |
[BP] GO:0032091 |
negative regulation of protein binding
|
AURKB, GSK3B, MET, PPARA |
2.08144 |
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, FLT3, KDR, KIT, MMP9, PTGS2, SRC, XDH |
2.07926 |
[BP] GO:0034405 |
response to fluid shear stress
|
CA2, PTGS2, SRC |
2.079 |
[BP] GO:0007566 |
embryo implantation
|
MMP2, MMP9, PTGS2 |
2.04554 |
[BP] GO:0030198 |
extracellular matrix organization
|
APP, CYP1B1, KDR, MMP1, MMP2, MMP9 |
2.04209 |
[BP] GO:0043062 |
extracellular structure organization
|
APP, CYP1B1, KDR, MMP1, MMP2, MMP9 |
2.03587 |
[BP] GO:0007584 |
response to nutrient
|
AKR1C3, CYP1A1, PTGS2, TRPV1, TYR |
2.03373 |
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, APP, AXL, CA2, CYP19A1, GSK3B, PTGS2, SRC, TRPV1 |
2.02802 |
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
ALOX12, CYP1A1, CYP1A2, CYP1B1 |
2.02802 |
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ALOX12, APP, AXL, CA2, CYP1B1, GSK3B, IDO1, KDR, KIT, MET, MMP9, PIM1, PTGS2, SRC, TRPV1, XDH |
2.02802 |
[BP] GO:0009820 |
alkaloid metabolic process
|
CYP1A2, CYP3A4 |
2.02802 |
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PTGS2, SRC, XDH |
2.02429 |
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, ALOX12, CYP19A1, FABP4, IDO1, KDR, MET, PPARA, PTGS2 |
2.01054 |
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, APP, AURKB, CA1, CA2, CA4, CA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, HSD11B1, HSD17B2, IDO1, KDR, KIT, MMP2, MMP9, NR3C1, PIM1, PTGS2, SRC, TOP1, TRPV1, TYR, XDH |
3.43665 |
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP |
1.92328 |
[CC] GO:0044459 |
plasma membrane part
|
ADORA1, ADORA3, ALOX15, APP, AXL, CA2, CA4, CA9, F10, FLT3, IGF1R, KDR, KIT, MET, PTGS2, SRC, TRPV1 |
1.8977 |
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ALOX12, ALOX15, ALOX5, APP, AXL, CA12, CA14, CA2, CA4, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, F10, FLT3, GSK3B, HSD11B1, HSD17B2, IGF1R, KDR, KIT, MET, MMP2, PIM1, PTGS2, SRC, TRPV1, TYR |
1.89714 |
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ALOX12, ALOX15, APP, AXL, CA12, CA14, CA2, CA4, CA9, F10, FLT3, GSK3B, IGF1R, KDR, KIT, MET, MMP2, PIM1, SRC, TRPV1 |
1.84902 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX12, ALOX15, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, MMP1, MMP2, MMP9, NR3C1, PIM1, PPARA, TYR, XDH |
11.4879 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, F10, FLT3, GSK3B, HSD11B1, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, PIM1, PTGS2, SRC, TOP1, TYR, XDH |
10.8681 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
10.8681 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX12, ALOX15, ALOX5, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, NR3C1, PIM1, PPARA, PTGS2, SRC, TOP1, TRPV1, TYR, XDH |
10.5763 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, HSD11B1, HSD17B2, IDO1, PTGS2, TYR, XDH |
9.72716 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.05998 |
[MF] GO:0005506 |
iron ion binding
|
ALOX12, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, XDH |
6.73822 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX12, ALOX15, ALOX5, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, F10, IDO1, KIT, MMP1, MMP2, MMP9, NR3C1, PIM1, PPARA, PTGS2, TRPV1, TYR, XDH |
6.46598 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.29028 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, IDO1, PTGS2, SRC |
6.21221 |
[MF] GO:0046872 |
metal ion binding
|
ALOX12, ALOX15, ALOX5, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, F10, IDO1, KIT, MMP1, MMP2, MMP9, NR3C1, PIM1, PPARA, PTGS2, TRPV1, TYR, XDH |
6.06479 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, IDO1, PTGS2, SRC |
6.0156 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, PPARA, SRC, TOP1, TRPV1 |
6.00491 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
5.90998 |
[MF] GO:0004497 |
monooxygenase activity
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, TYR |
5.77206 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, PTGS2, TYR |
5.71287 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
5.68701 |
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX12, ALOX15, ALOX5, IDO1, PTGS2 |
5.68701 |
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX12, ALOX15, ALOX5, IDO1, PTGS2 |
5.63541 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET |
5.47088 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET |
4.90466 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
4.64171 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, IDO1, PTGS2, SRC, XDH |
4.2285 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.1773 |
[MF] GO:0016829 |
lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
4.13652 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC, TOP1 |
4.00314 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AKR1C3, HSD11B1, HSD17B2, XDH |
3.72034 |
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
3.69645 |
[MF] GO:0051213 |
dioxygenase activity
|
ALOX12, ALOX15, ALOX5, IDO1, PTGS2 |
3.33516 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC, TOP1 |
3.31976 |
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AKR1C3, XDH |
3.2009 |
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA7, CA9, MMP1, MMP2, MMP9, NR3C1, PPARA |
3.2009 |
[MF] GO:0045550 |
None
|
AKR1B10, AKR1C3 |
3.10793 |
[MF] GO:0047977 |
hepoxilin-epoxide hydrolase activity
|
ALOX12, ALOX15 |
3.10793 |
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC, TOP1 |
3.02256 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, CYP19A1, CYP1A2, IDO1, XDH |
3.02256 |
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, AKR1C3, HSD11B1, HSD17B2 |
2.84081 |
[MF] GO:0043168 |
anion binding
|
ALOX15, APP, AURKB, AXL, DHFR, F10, FABP3, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC, TOP1, TRPV1, XDH |
2.70292 |
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.6935 |
[MF] GO:0047718 |
None
|
AKR1B10, AKR1C3 |
2.6935 |
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.6935 |
[MF] GO:0004052 |
arachidonate 12-lipoxygenase activity
|
ALOX12, ALOX15 |
2.6935 |
[MF] GO:0051120 |
hepoxilin A3 synthase activity
|
ALOX12, ALOX15 |
2.6935 |
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC, TOP1 |
2.44361 |
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.44361 |
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.44361 |
[MF] GO:0004033 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.44079 |
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1C3, HSD11B1, HSD17B2 |
2.39886 |
[MF] GO:0008289 |
lipid binding
|
ALOX15, AXL, CYP3A4, F10, FABP3, FABP4, NR3C1, PPARA, TRPV1 |
2.39071 |
[MF] GO:0016229 |
steroid dehydrogenase activity
|
AKR1C3, HSD11B1, HSD17B2 |
2.32098 |
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AURKB, AXL, DHFR, FABP3, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC, TOP1, TRPV1, XDH |
2.28883 |
[MF] GO:0101020 |
estrogen 16-alpha-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.27277 |
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP3A4 |
2.16729 |
[MF] GO:0016709 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
|
AKR1C3, CYP1A1, CYP3A4 |
2.16729 |
[MF] GO:0004064 |
arylesterase activity
|
CA1, CA2 |
2.14246 |
[MF] GO:0047035 |
testosterone dehydrogenase (NAD+) activity
|
AKR1C3, HSD17B2 |
2.14246 |
[MF] GO:0005021 |
vascular endothelial growth factor-activated receptor activity
|
FLT3, KDR |
2.02802 |
[MF] GO:0001758 |
None
|
AKR1B10, AKR1C3 |
2.02802 |
[MF] GO:0004032 |
None
|
AKR1B1, AKR1C3 |
2.02802 |
[MF] GO:0001609 |
None
|
ADORA1, ADORA3 |
2.02802 |