| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, APP, CBR1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, EGFR, ESR1, FABP3, FABP4, FDPS, FUCA1, FUT7, GBA, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, TRPV1 |
17.226 |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GAA, GBA, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, GSK3B, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, XDH |
17.0164 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AXL, BCL2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, GBA, GRIK5, GRM5, GSK3B, HMGCR, HSD11B2, HSD17B2, IDO1, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
16.6477 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GBA, GRIK5, GRM5, GSK3B, HIF1A, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
15.2431 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, FABP3, FDPS, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HMGCR, HSPA1A, IDO1, MIF, PIK3CA, PIM1, PPARA, PTGS1, PTGS2, TYR, XDH |
13.8106 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GBA, GPR35, GRM1, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.7445 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GBA, GRIK5, GRM5, GSK3B, HIF1A, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
13.7445 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GBA, GPR35, GRM1, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.7236 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GSK3B, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
12.8591 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GBA, GPR35, GRIK5, GRM1, GRM5, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
12.3634 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BACE1, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GBA, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.2132 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2 |
12.1318 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX12, ALOX15, ALOX5, CBR1, CES2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, EGFR, FABP3, FABP4, FDPS, FUCA1, FUT7, GBA, GBA2, HMGCR, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2 |
12.1028 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BACE1, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GBA, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.0526 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2 |
11.792 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, ALOX12, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GBA, GLO1, GRIK5, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.7088 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GBA, GPR35, GRIK5, GRM1, GRM5, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
11.5211 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, GAA, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, NQO2, PTGS1, PTGS2, TYR, XDH |
11.3497 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.286 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, ESR1, FDPS, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
11.2614 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GSK3B, HIF1A, HMGCR, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP2, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
11.2043 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, APP, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DNMT1, DRD1, DRD5, EGFR, ESR1, ESRRA, FABP3, FLT3, GBA, GRM5, GSK3B, HSD11B2, IGF1R, INSR, MMP2, NR3C1, PPARA, PTGS2, SMAD3, SRC, TEK, TRPV1 |
11.2043 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, ALOX12, APP, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NUAK1, PIM1, PTGS1, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
11.1118 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FLT3, GBA, HSD11B2, NR3C1, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
11.0732 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX12, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2 |
10.9692 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, GBA, GRIK5, GRM5, GSK3B, HIF1A, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, PIK3CA, PTGS2, RORC, SMAD3, SRC, TERT, TRPV1 |
10.9429 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
10.7765 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GRM1, GSK3B, HIF1A, HMGCR, HSPA1A, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.7099 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, GBA, GRIK5, GRM5, GSK3B, HIF1A, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PTGS2, RORC, SMAD3, SRC, TRPV1 |
10.4064 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, ALOX12, AURKB, AXL, BCL2, CSNK2A1, EGFR, GBA, GLO1, GSK3B, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
9.99835 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GSK3B, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
9.98251 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GBA, GRM1, GRM5, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.87291 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, ALOX12, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, FLT3, GAA, GBA, GPR35, GRIK5, GRM1, GRM5, HIF1A, INSR, MET, PIK3CA, PIK3CB, SMAD3, SRC, TERT, TRPV1 |
9.86285 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
9.68831 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2 |
9.6595 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DAO, DRD1, DRD2, DRD3, FDPS, GBA, GBA2, HIF1A, HMGCR, TYR |
9.6595 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, DRD1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HMGCR, KDR, MIF, PIK3CB, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
9.54221 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, GSK3B, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
9.37682 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GBA, GRM1, GRM5, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.31795 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GSK3B, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
9.31795 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
9.16777 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPR35, GRM3, GRM8, GSK3B, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.16777 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, GBA, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
9.16777 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX12, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA7, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, GPR35, GRIK5, GRM5, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TRPV1 |
9.16777 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
9.15585 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, ALOX12, APP, CDK6, CYP19A1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, GBA, GSK3B, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, MET, MIF, MMP12, MMP2, NUAK1, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
9.12428 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GBA, GRM1, GRM3, GRM5, GRM8, HIF1A, HMGCR, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.10974 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, APP, AXL, BCL2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, GAA, GBA, GRM1, GRM5, GRM8, HIF1A, HMGCR, HSD11B2, HSD17B2, IDO1, IGF1R, INSR, MET, MGAM, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, TYR |
9.09122 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, BACE1, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, PTGS2 |
9.0505 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, BACE1, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, PTGS2 |
9.0505 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GBA, GRM1, GRM3, GRM5, GRM8, HIF1A, HMGCR, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.03706 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
8.99837 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, GSK3B, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MIF, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.86221 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESRRA, F10, F3, FABP4, FLT3, GPR35, GRM1, GSK3B, HIF1A, HMGCR, HSPA1A, IDO1, INSR, KDR, MET, MIF, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
8.84604 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GBA, GRM1, GRM5, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.78606 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, ALOX12, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, GBA, GPR35, GRIK5, GRM1, GRM5, HIF1A, INSR, MET, PIK3CA, PIK3CB, SMAD3, TRPV1 |
8.70723 |
|
[BP] GO:0032787 |
None
|
ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, PPARA, PTGS1, PTGS2 |
8.70309 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ESRRB, FABP3, FLT3, GBA, GRM1, GRM5, HIF1A, HMGCR, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.70309 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ESRRB, FABP3, FLT3, GBA, GRM1, GRM5, HIF1A, HMGCR, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.70309 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, GBA, GRIK5, GRM1, GRM5, GSK3B, HIF1A, HSPA1A, IGF1R, INSR, KDR, MIF, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TOP2A, TRPV1 |
8.68003 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
8.49673 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AXL, CDK6, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ESR1, GRIK5, GRM5, GSK3B, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PTGS2, RORC, SRC, TRPV1 |
8.47654 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPR35, GRM3, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.47654 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, INSR, KDR, MET, MIF, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
8.44521 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, GBA, GRIK5, GRM1, GRM5, GSK3B, HIF1A, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TYR |
8.42121 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX12, ALOX15, BCL2, CDK6, CYP19A1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GBA, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
8.38451 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX12, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2 |
8.32676 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GBA, GRM1, GRM5, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.26602 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, MIF, PPARA, PTGS1, PTGS2 |
8.25031 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, HIF1A, KDR, MMP9, PTGS2, SRC, TERT |
8.1369 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, AKR1B1, ALOX12, ALOX15, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GBA, GPR35, GRM1, GSK3B, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
8.13614 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GBA, HSD11B2, HSD17B2, IDO1, NR3C1, PTGS2, RORC, SRC, TYR |
8.09239 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GBA, HSD11B2, INSR, NR3C1, PPARA, PTGS2, SRC, TEK, TRPV1 |
8.02338 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCL2, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GBA, GPR35, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
7.93725 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, GBA, HMGCR, HSD11B2, KDR, NR3C1, PTGS2, SRC, TRPV1 |
7.93503 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCL2, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GBA, GPR35, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
7.91902 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, ALOX12, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, HIF1A, HMGCR, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, PIM1, PTGS2, TEK, TERT |
7.90616 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, DRD1, DRD2, EGFR, GRM1, GRM3, GRM5, GRM8, PTGS2 |
7.83417 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX12, ALOX15, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, FDPS, GBA, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MIF, PIK3CA, PIK3CB, PTGS1, PTGS2 |
7.74561 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, GRM5, GSK3B, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TRPV1, TYR |
7.68074 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GBA, GRM1, GRM3, GRM5, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
7.64995 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
7.60029 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, GBA, GRM1, HIF1A, HMGCR, HSD11B2, HSPA1A, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
7.53674 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GBA, GPR35, GRM1, GRM3, GRM5, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TRPV1, XDH |
7.48637 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.43484 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
7.37207 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GAA, GBA, GBA2, GLO1, GSK3B, HIF1A, HMGCR, HSD11B1, HSD17B2, INSR, KDR, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
7.32613 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AURKB, BCL2, CSNK2A1, CYP2D6, DNMT1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GBA, GRM3, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
7.30855 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FDPS, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, XDH |
7.23403 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
7.19703 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, F10, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
7.14567 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GBA, GPR35, GRM1, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
7.12112 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, GRM5, GSK3B, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TRPV1, TYR |
7.09667 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ALOX12, APP, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GAA, GBA, GPR35, GRM1, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IDO1, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PTGS2, PTPRS, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
7.08097 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.97395 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DAO, FABP3, FABP4, FUCA1, FUT7, GAA, GBA, GBA2, GSK3B, HSPA1A, IDO1, MGAM, MMP1, MMP12, MMP2, MMP9, PIK3CB, SRC, XDH |
6.81068 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, DRD1, DRD2, DRD3, EGFR, HCAR2, HIF1A, PIK3CB, PTGS2, TNKS, TNKS2 |
6.80948 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TYR |
6.74367 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, ALOX12, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, GBA, HMGCR, IDO1, KDR, MET, MIF, MMP12, PPARA, PTGS2, PTPRS, SMAD3, TEK |
6.74286 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FDPS, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, XDH |
6.73938 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CYP19A1, DRD1, DRD2, DRD3, EGFR, GPR35, GRIK5, GRM5, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, INSR, MIF, MMP12, MMP9, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TERT, TRPV1 |
6.68153 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DRD3, DUSP3, DYRK1A, ESR1, GBA, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP9, PTGS2, PTPN1, SRC, XDH |
6.60863 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4, NQO2, PTGS1, RORC |
6.60637 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
6.54267 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, DYRK1A, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, PIM1, SRC, TEK |
6.47975 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DAO, DRD1, DRD2, DRD3, EGFR, HSPA1A, IDO1 |
6.47829 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, GBA, GRM1, GRM5, HIF1A, HMGCR, IGF1R, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SRC, TEK, XDH |
6.45853 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, CYP1A1, CYP1B1, DRD1, DRD5, EGFR, ESR1, FLT3, NR3C1, PTGS2, RORC, SRC, TRPV1 |
6.40567 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DYRK1A, EGFR, ESR1, F3, FLT3, GBA, GRM1, GRM5, GSK3B, HMGCR, HSPA1A, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.34485 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, GRM1, GRM5, HIF1A, HMGCR, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
6.33238 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ESR1, F3, FLT3, GBA, GRM1, GRM5, GSK3B, HMGCR, HSPA1A, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.30108 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DRD5, DUSP3, ESR1, FABP4, GBA, GPR35, GRM3, GSK3B, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TNKS |
6.28764 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ALOX12, APP, AXL, BCL2, CA2, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, GBA, HCAR2, HIF1A, HMGCR, HSPA1A, IDO1, KDR, MET, MIF, MMP12, MMP9, PIM1, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TRPV1 |
6.28764 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, IGF1R, INSR, KDR, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
6.19001 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TERT |
6.17138 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TERT |
6.01871 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TYR |
6.00836 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.00222 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AURKB, BCL2, CSNK2A1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GBA, GRM3, GRM8, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
5.97472 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, EGFR, ESR1, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.94391 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, GRM5, HIF1A, HMGCR, INSR, PTGS2 |
5.94391 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, APP, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, DRD3, EGFR, GSK3B, HCAR2, HIF1A, INSR, MIF, MMP12, PTGS2, SMAD3, SRC, TERT, TRPV1 |
5.90149 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, CYP3A4, DAO, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, FUCA1, FUT7, GBA, GBA2, GLO1, GSK3B, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
5.8904 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TYR |
5.8904 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, ALOX12, CYP19A1, DRD1, DRD2, DRD3, GBA, HMGCR, MIF, PPARA, PTPRS, SMAD3, TEK |
5.82258 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD5, EGFR, GRM5, GSK3B, IGF1R, INSR, MMP2, PTGS2, SRC, TRPV1 |
5.78755 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.75411 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, DYRK1A, EGFR, ESR1, GSK3B, PPARA, RORC, SRC, TOP2A |
5.74069 |
|
[BP] GO:0050801 |
ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
5.74069 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, APP, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ESR1, ESR2, F3, FLT3, GRM1, GRM5, GSK3B, HIF1A, HSPA1A, INSR, MET, MIF, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.66541 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TERT |
5.62719 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, GAA, GRM1, GRM5, HIF1A, HMGCR, IDO1, INSR, PPARA, PTGS2, TRPV1 |
5.6131 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD5, EGFR, ESR1, FLT3, GRM5, GSK3B, IGF1R, INSR, MMP2, NR3C1, PTGS2, SMAD3, SRC, TRPV1 |
5.6131 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GRM5, GSK3B, HSD11B2, IGF1R, INSR, PPARA, PTGS2, SRC, TEK, TRPV1 |
5.60866 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GBA, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
5.56868 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DNMT1, DRD3, GBA, GSK3B, HIF1A, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
5.56221 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HIF1A, HSD11B1, HSD17B2, INSR, KDR, PIK3CA, PPARA, PTPRS, SMAD3, SRC, TEK, TYR |
5.56207 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.54237 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK |
5.53607 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, GSK3B, HMGCR, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
5.53484 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, IGF1R, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.52145 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DYRK1A, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, SRC, TEK, TNKS |
5.49363 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FDPS, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.43244 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, FLT3, GBA, GRM1, GRM5, HMGCR, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.4259 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
5.41924 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, ALOX12, DRD1, DRD2, GBA, MET, PIK3CA, TRPV1 |
5.39781 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APEX1, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GAA, GPR35, GRIK5, GRM1, GRM5, HIF1A, PIK3CA, PIK3CB, SMAD3, TRPV1 |
5.39781 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD5, EGFR, GRM5, GSK3B, IGF1R, INSR, MMP2, PTGS2, SRC, TRPV1 |
5.39531 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, GRIK5, INSR, PTGS2, SLC1A1, SMAD3, TRPV1 |
5.36455 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.3301 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.3301 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
5.32595 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, DRD2, DUSP3, EGFR, FLT3, GBA, GRM1, HMGCR, IGF1R, INSR, KDR, MIF, PIK3CB, PTPN1, SRC, TEK, XDH |
5.32595 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX12, ALOX15, CYP19A1, CYP3A4, DAO, FDPS, GBA, HMGCR, TYR |
5.31358 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, APP, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ESR1, F3, FLT3, GRM1, GRM5, GSK3B, HIF1A, HSPA1A, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.29252 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, DYRK1A, EGFR, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, NUAK1, PTGS2, PTPN1, PTPRS, TERT, XDH |
5.2673 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FDPS, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.25569 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, HIF1A, MMP9, PTGS2, TERT |
5.23589 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRIK5, GRM1, GRM5, HIF1A, PIK3CA, PIK3CB, SMAD3, TRPV1 |
5.23382 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, FUCA1, GBA, GBA2 |
5.23147 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, DRD2, EGFR, FLT3, GRM1, HMGCR, INSR, KDR, MIF, PIK3CB, PTPN1, SRC, TEK, XDH |
5.22401 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, EGFR, FDPS, HMGCR |
5.2224 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, FDPS, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.19671 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
5.17651 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.13211 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, BCL2, DNMT1, DRD2, DRD3, ESR1, GBA, GSK3B, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
5.11146 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, HIF1A, HMGCR, INSR, PTGS2 |
5.11073 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX12, ALOX15, ALOX5, MIF, PTGS1, PTGS2 |
5.11019 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APP, AXL, BCL2, CA2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESRRA, ESRRB, FLT3, GAA, GBA2, GSK3B, HIF1A, HSD11B1, HSD17B2, INSR, KDR, MMP9, PIK3CA, PIM1, PPARA, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TYR |
5.10563 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, APP, AXL, BCL2, CA1, CA2, CDK6, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
5.03449 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
5.02888 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DRD2, DRD5, EGFR, PPARA, SMAD3 |
4.96057 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, HMGCR, KDR, SRC |
4.96057 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GBA, GRM1, HMGCR, IGF1R, INSR, MIF, PIK3CB, PTPN1, SRC |
4.96057 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, KDR, NR3C1, PTGS2, SRC, TRPV1 |
4.96054 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
4.93553 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.91211 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, GBA, HIF1A, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
4.88098 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.8589 |
|
[BP] GO:0007611 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, HIF1A, HMGCR, INSR, PTGS2 |
4.84662 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.82666 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD5, EGFR, GBA, GSK3B, HIF1A, HSD11B2, HSPA1A, IDO1, MIF, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1 |
4.82461 |
|
[BP] GO:0055080 |
cation homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
4.79944 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, GSK3B, KDR, PIK3CB, SMAD3, SRC, TEK |
4.78606 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3, TRPV1 |
4.78339 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, TRPV1 |
4.78339 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.77328 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC |
4.77299 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HMGCR, MIF, SRC, TNKS, TNKS2, TRPV1 |
4.76325 |
|
[BP] GO:0008306 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, HIF1A, HMGCR |
4.72658 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
4.68607 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DYRK1A, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TNKS |
4.67565 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, EGFR, FDPS |
4.67565 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, DRD3, FABP3, FDPS, FLT3, HCAR2, HMGCR, PPARA, PTGS2, RORC, SRC, TEK |
4.67565 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7, GRM5 |
4.66913 |
|
[BP] GO:0008217 |
None
|
ADORA1, DRD2, DRD3, DRD5, HSD11B2, PPARA, PTGS1, PTGS2, SMAD3 |
4.65032 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2 |
4.65032 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, INSR, MIF, SRC, TERT |
4.58014 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.57099 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
4.56556 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX12, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP3A4, FDPS, GBA, HMGCR, IDO1, MIF, PTGS1, PTGS2 |
4.5581 |
|
[BP] GO:0007193 |
None
|
ADORA1, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8 |
4.54996 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2, TERT |
4.54996 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TERT, TNKS, TOP2A |
4.54876 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, GBA, HIF1A, IGF1R, INSR, MET, MMP12, NR3C1, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
4.53789 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, GBA, HSD11B2, NR3C1, PTGS2, SRC |
4.5267 |
|
[BP] GO:0007188 |
None
|
ADORA1, DRD1, DRD2, DRD3, DRD5, GRM1, GRM3, GRM5, GRM8 |
4.50473 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, DRD3, HIF1A, HMGCR |
4.50076 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DAO, DRD1, DRD2, DRD3, TYR |
4.48394 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3, TRPV1 |
4.47297 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.46686 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, DRD3, KDR, SRC, TRPV1 |
4.44438 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.41248 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ALOX12, APP, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GSK3B, HIF1A, HMGCR, IDO1, INSR, KDR, MIF, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
4.37992 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, HIF1A, IDO1, MIF, PIK3CB |
4.35573 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CYP1B1, F3, GRIK5, GSK3B, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
4.34487 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3, TRPV1 |
4.34355 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, FUCA1, GBA, GBA2 |
4.33202 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AURKB, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, HIF1A, HSPA1A, IGF1R, INSR, MET, MMP12, NR3C1, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
4.33059 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, DRD1, DRD2, EGFR, PTGS2 |
4.32923 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CYP1B1, F3, GRIK5, GSK3B, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
4.29639 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, PIK3CB, SMAD3, TRPV1 |
4.2896 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AURKB, CSNK2A1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GBA, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, MIF, MMP12, MMP9, NR3C1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
4.28662 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, DUSP3, EGFR, HMGCR, KDR, MIF, PTPN1, SRC, TEK |
4.27961 |
|
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, DRD3, HIF1A, HMGCR |
4.27961 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, DRD1, GBA, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
4.27254 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX12, ALOX15, MIF, PTGS1, PTGS2 |
4.27254 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, GBA, HSD11B2, NR3C1, PTGS2, SRC |
4.27254 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, HIF1A, INSR, PTGS2, SMAD3, TRPV1, XDH |
4.26309 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
4.24353 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.22274 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, DRD2, EGFR, ESR1, FABP4, GBA, HSPA1A, IDO1, MMP12, MMP2, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK |
4.20659 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PTGS1, PTGS2, SRC |
4.182 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, CYP2D6, GSK3B, MET, MMP9, PPARA, SMAD3, SRC, TERT, TNKS |
4.182 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PIM1, PPARA, RORC, SRC |
4.1482 |
|
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DAO, FABP3, FABP4, FUCA1, FUT7, GAA, GBA, GBA2, GSK3B, HSPA1A, IDO1, MGAM, XDH |
4.13998 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HIF1A, HMGCR, PTGS2, TYR |
4.13451 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, RORC, SRC |
4.12656 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
APP, BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, HIF1A, PIK3CB, SMAD3, TRPV1 |
4.12403 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.10045 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSPA1A, INSR, MIF, PIM1, PTGS2, SMAD3, SRC, TERT, TNKS, TOP2A |
4.08677 |
|
[BP] GO:1900542 |
None
|
DRD1, DRD2, DRD3, DRD5, ESRRB, GRM3, GRM8, HIF1A, INSR, PPARA |
4.04049 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DAO, DRD1, DRD2, DRD3, GBA |
4.0222 |
|
[BP] GO:0007187 |
None
|
ADORA1, DRD1, DRD2, DRD3, DRD5, GRM1, GRM3, GRM5, GRM8 |
4.00385 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX12, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESR2, GBA, GRIK5, GSK3B, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PIK3CB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
4.00016 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
3.98991 |
|
[BP] GO:0040008 |
regulation of growth
|
ALOX12, APP, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR2, HIF1A, HSPA1A, INSR, PIK3CA, PIM1, PTPRS, SMAD3, TNKS2 |
3.98617 |
|
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.98048 |
|
[BP] GO:0003008 |
None
|
ADORA1, AKR1B1, APP, BCL2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GAA, GRM1, GRM5, GRM8, HIF1A, HMGCR, HSD11B2, INSR, PIK3CA, PTGS2, SRC, TEK, TRPV1, TYR |
3.96574 |
|
[BP] GO:0006140 |
None
|
DRD1, DRD2, DRD3, DRD5, ESRRB, GRM3, GRM8, HIF1A, INSR, PPARA |
3.93758 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CSNK2A1, EGFR, ESRRB, GBA, GSK3B, HCAR2, HIF1A, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PTPN1, SMAD3 |
3.9358 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, GBA, HSD11B2, NR3C1, PTGS2 |
3.92941 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CYP1B1, F3, GRIK5, GSK3B, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.92598 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, GSK3B, KDR, PIK3CB, SMAD3, SRC, TEK |
3.92213 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, FLT3, GBA, GRM1, GRM5, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.92011 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, PTGS2 |
3.87262 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX12, ALOX15, ALOX5, PTGS2 |
3.87262 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX12, ALOX15, BCL2, CDK6, CYP1B1, DUSP3, GSK3B, IDO1, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, SMAD3, SRC, TEK |
3.86803 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, DRD1, DRD2, DRD5, PTGS2 |
3.85034 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, TERT |
3.82765 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, DRD2, DRD3, EGFR, GAA, GBA, GPR35, GRM1, HCAR2, PTGS2, SLC1A1, SMAD3, TRPV1 |
3.81645 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
ALOX12, BCL2, CYP1A1, CYP1A2, CYP1B1, DRD5, EGFR |
3.79592 |
|
[BP] GO:0007212 |
None
|
DRD1, DRD2, DRD3, DRD5, GSK3B |
3.79005 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CDK6, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, HCAR2, HIF1A, HSPA1A, IDO1, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PTPN1, PTPRS, SMAD3, SRC |
3.78505 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, EGFR, HMGCR, KDR, MIF, SRC, TEK |
3.77467 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HCAR2, HIF1A, MIF, MMP12, SRC, TRPV1 |
3.75087 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
3.75067 |
|
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AOX1, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DAO, FABP3, FABP4, FUCA1, GAA, GBA, GBA2, GSK3B, HSPA1A, IDO1, MGAM, PIK3CB, SRC, XDH |
3.74973 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
APP, BCL2, DRD2, DRD3, PIK3CA, TNKS2 |
3.74818 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GBA, GLO1, GRM1, GRM5, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.73474 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, APP, AXL, BCL2, CBR1, CDC25B, CDK6, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, GSK3B, HIF1A, HMGCR, KDR, MET, MIF, MMP2, MMP9, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TOP2A |
3.72673 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR, IDO1 |
3.67785 |
|
[BP] GO:0007154 |
None
|
ADORA1, AXL, BCL2, DRD1, DRD2, DRD3, DRD5, ESR2, GBA, GRIA2, GRIK5, GRM1, GRM3, GRM5, PTGS2, SLC1A1, TEK, TRPV1 |
3.66834 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUCA1, FUT7, GAA, HSPA1A, MGAM, MIF, MMP9, PIK3CA, PIK3CB, RORC, SMAD3, SRC, TRPV1 |
3.66834 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
3.65154 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, GSK3B, MET, MMP9, PPARA, SRC, TERT |
3.65086 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
ALOX12, CYP1B1, F3, HIF1A, KDR, PTGS2, TEK, TERT |
3.63834 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AURKB, CSNK2A1, DNMT1, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GBA, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, KDR, MIF, MMP12, MMP9, NR3C1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
3.63804 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, DRD1, DRD5, EGFR, ESR1, ESRRB, HIF1A, HSD11B2, HSD17B2, IDO1, INSR, MMP2, MMP9, PTGS2, SRC, TOP2A |
3.62663 |
|
[BP] GO:0003018 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, PTGS2, SRC, TEK |
3.62118 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, DYRK1A, EGFR, F10, FLT3, GSK3B, IGF1R, INSR, KDR, MET, SRC, TEK, TNKS, TOP2A |
3.61765 |
|
[BP] GO:2001300 |
lipoxin metabolic process
|
ALOX12, ALOX15, ALOX5 |
3.6129 |
|
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.6129 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, TRPV1 |
3.60538 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.59582 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.59582 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
3.58165 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
3.56921 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC, TERT |
3.56465 |
|
[BP] GO:0045776 |
None
|
ADORA1, DRD2, DRD3, DRD5, PPARA |
3.54766 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GAA, GRM1, GRM5, GRM8, HIF1A, HMGCR, INSR, PTGS2, TRPV1, TYR |
3.5281 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, HSPA1A, INSR, MIF, TERT, TNKS |
3.51799 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.51725 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DAO, DRD1, DRD2, DRD3 |
3.5032 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DAO, DRD1, DRD2, DRD3 |
3.5032 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, DRD2, DRD3, EGFR, GSK3B, HCAR2, HIF1A, HMGCR, MIF, MMP12, PTGS2, PTPN1, SMAD3, SRC |
3.4748 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
3.43502 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, GSK3B, KDR, SMAD3, TEK |
3.40963 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, RORC, SRC |
3.40818 |
|
[BP] GO:0051241 |
negative regulation of multicellular organismal process
|
ADORA1, ALOX12, APP, AXL, BCL2, CDK6, DRD2, DRD3, EGFR, GBA, GPR35, GSK3B, HIF1A, IDO1, PTGS2, PTPRS, SMAD3, TEK, TERT, XDH |
3.40287 |
|
[BP] GO:0009820 |
alkaloid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.39683 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, MET, MIF, PIK3CB, PIM1, SRC, TEK, TYR |
3.38152 |
|
[BP] GO:1901570 |
None
|
ALOX12, ALOX15, ALOX5, MIF, PTGS1, PTGS2 |
3.34762 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, DRD2, GBA, MMP12, PPARA, SMAD3, TEK |
3.34076 |
|
[BP] GO:2000107 |
negative regulation of leukocyte apoptotic process
|
AURKB, AXL, HIF1A, IDO1, MIF |
3.32644 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.32644 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GBA, GRM1, HMGCR, IGF1R, INSR, MIF, PIK3CB, PTPN1, SRC |
3.31156 |
|
[BP] GO:0050789 |
regulation of biological process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.30438 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, FLT3, GBA, GRM1, GRM5, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.2964 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7, GRM5, MIF |
3.29337 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
3.29337 |
|
[BP] GO:0045934 |
None
|
APEX1, AURKB, DNMT1, DRD2, DRD3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HSPA1A, MMP12, NR3C1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1 |
3.2926 |
|
[BP] GO:0007268 |
None
|
DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, SLC1A1 |
3.2926 |
|
[BP] GO:0098916 |
None
|
DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, SLC1A1 |
3.2926 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
HIF1A, KDR, MET, MMP9, PTGS2, SRC, TEK |
3.28419 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
ALOX12, CYP1B1, F3, HIF1A, KDR, PTGS2, TEK, TERT |
3.28075 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CYP1A1, EGFR, GBA, HMGCR, HSD11B2, PTGS2, SRC, TRPV1, TYR |
3.27858 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK |
3.24642 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, INSR, MIF, PIK3CA, PIK3CB, PTPN1, SRC |
3.2253 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, GBA, HIF1A, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
3.2253 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2, TERT |
3.22326 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.22269 |
|
[BP] GO:0016139 |
None
|
FUCA1, GBA, GBA2 |
3.22269 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.22269 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, DRD2, EGFR, GSK3B, HCAR2, HIF1A, MIF, MMP12, PTGS2, SMAD3, SRC |
3.22247 |
|
[BP] GO:0007626 |
None
|
APP, DRD1, DRD2, DRD3, GAA, GRM1, GRM5, IDO1 |
3.22055 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
3.22055 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.22055 |
|
[BP] GO:0099536 |
None
|
DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, SLC1A1 |
3.22055 |
|
[BP] GO:0099537 |
None
|
DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, SLC1A1 |
3.22055 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.13738 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ABCB1, ADORA1, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, GPR35, GRM5, MIF, MMP9, PTGS2 |
3.12169 |
|
[BP] GO:1901215 |
negative regulation of neuron death
|
AXL, BCL2, GBA, GSK3B, HIF1A, PIK3CA, PPARA, TERT |
3.10893 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1, XDH |
3.09115 |
|
[BP] GO:0046466 |
None
|
CYP1B1, FUCA1, GBA, GBA2 |
3.09115 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
3.09115 |
|
[BP] GO:0001975 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.09115 |
|
[BP] GO:0006693 |
None
|
CES2, MIF, PTGS1, PTGS2 |
3.09115 |
|
[BP] GO:0006692 |
None
|
CES2, MIF, PTGS1, PTGS2 |
3.09115 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
BCL2, GSK3B, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SMAD3, SRC, TERT |
3.08194 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, DYRK1A, EGFR, GSK3B, PPARA, RORC |
3.07698 |
|
[BP] GO:1904646 |
cellular response to amyloid-beta
|
APP, GRM5, GSK3B, IGF1R |
3.02969 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, GBA, IDO1, PPARA, PTGS2, SMAD3, TEK |
3.01494 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
ALOX12, APP, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, GSK3B, HIF1A, HMGCR, IDO1, INSR, KDR, PIM1, PTGS2, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
2.99757 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
2.99412 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, DRD2, DRD3, GPR35, MMP9, PTGS2 |
2.98347 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, HIF1A, MIF, MMP12, SRC |
2.98218 |
|
[BP] GO:0033032 |
regulation of myeloid cell apoptotic process
|
BCL2, HCAR2, MIF, PIK3CB |
2.97183 |
|
[BP] GO:0042417 |
None
|
DAO, DRD1, DRD2, DRD3 |
2.97183 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.96528 |
|
[BP] GO:0010906 |
None
|
ESRRB, GSK3B, INSR, PPARA, RORC, SRC |
2.95059 |
|
[BP] GO:0007191 |
None
|
DRD1, DRD3, DRD5 |
2.93296 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.93296 |
|
[BP] GO:0070229 |
negative regulation of lymphocyte apoptotic process
|
AURKB, HIF1A, IDO1, MIF |
2.91535 |
|
[BP] GO:0030817 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8 |
2.90555 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, RORC, TOP2A |
2.90555 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.9007 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP2D6, CYP3A4 |
2.9007 |
|
[BP] GO:0009410 |
None
|
DRD1, DRD2, DRD3, DRD5, EGFR, GBA, NR3C1 |
2.89973 |
|
[BP] GO:0033043 |
regulation of organelle organization
|
ALOX15, AURKB, BCL2, DNMT1, DRD3, GBA, GRIK5, GSK3B, HIF1A, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.89896 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
AKR1B1, AXL, BCL2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, GSK3B, IGF1R, INSR, KDR, MET, MIF, NUAK1, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
2.89496 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.88637 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, GRM1, INSR, MIF, PIK3CB, PTPN1, SRC |
2.88048 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, DRD2, EGFR, GSK3B, HCAR2, HIF1A, MIF, MMP12, PTGS2, SMAD3, SRC |
2.87346 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, DRD2, DRD3, EGFR, GSK3B, HCAR2, HIF1A, HMGCR, MIF, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.87203 |
|
[BP] GO:0072330 |
monocarboxylic acid biosynthetic process
|
ALOX12, ALOX15, CYP1A1, IDO1, MIF, PTGS1, PTGS2 |
2.86983 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.86983 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CYP1A1, EGFR, GBA, HMGCR, HSD11B2, PTGS2, SRC, TRPV1, TYR |
2.86983 |
|
[BP] GO:1904645 |
response to amyloid-beta
|
APP, GRM5, GSK3B, IGF1R |
2.86983 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CYP19A1, DRD2, DUSP3, IDO1, MIF, MMP12, PTPRS |
2.86167 |
|
[BP] GO:0003013 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, PTGS2, SRC, TEK |
2.84896 |
|
[BP] GO:0019371 |
None
|
CBR1, PTGS1, PTGS2 |
2.81659 |
|
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2, TRPV1 |
2.81659 |
|
[BP] GO:0010039 |
response to iron ion
|
BCL2, CYP1A1, DRD2, HIF1A |
2.81659 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.81273 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GRM5, GSK3B, IGF1R, INSR, SRC |
2.80966 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, BCL2, CSNK2A1, DRD2, DRD3, EGFR, GSK3B, HCAR2, HIF1A, HMGCR, MIF, MMP12, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.80657 |
|
[BP] GO:0046960 |
None
|
DRD1, DRD5 |
2.79965 |
|
[BP] GO:0006680 |
None
|
GBA, GBA2 |
2.79965 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.79965 |
|
[BP] GO:2001301 |
lipoxin biosynthetic process
|
ALOX12, ALOX15 |
2.79965 |
|
[BP] GO:2001302 |
lipoxin A4 metabolic process
|
ALOX12, ALOX15 |
2.79965 |
|
[BP] GO:2001303 |
lipoxin A4 biosynthetic process
|
ALOX12, ALOX15 |
2.79965 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, APEX1, APP, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FDPS, GBA, GLO1, GRM3, GRM5, GRM8, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.79866 |
|
[BP] GO:0048167 |
None
|
ADORA1, APP, DRD1, DRD2, DRD5, GRM5, PTGS2 |
2.7834 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, TERT |
2.7834 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, DRD2 |
2.78099 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.75659 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
HIF1A, MMP1, MMP12, MMP2, MMP9, TRPV1 |
2.75485 |
|
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, CDK6, GSK3B, KDR, SMAD3, TEK |
2.75485 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, PTGS2, SRC, TEK, TRPV1 |
2.74253 |
|
[BP] GO:1901214 |
regulation of neuron death
|
AXL, BCL2, GBA, GRIK5, GSK3B, HIF1A, PIK3CA, PPARA, TERT |
2.74253 |
|
[BP] GO:0009314 |
response to radiation
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HIF1A, HMGCR, PTGS2, TYR |
2.74035 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.73759 |
|
[BP] GO:1902893 |
None
|
HIF1A, PPARA, SMAD3, TERT |
2.73671 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.73671 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
EGFR, F3, FABP4, IDO1, KDR, MET, MIF, PTGS2, SMAD3 |
2.73486 |
|
[BP] GO:0042738 |
exogenous drug catabolic process
|
CYP1A2, CYP2A6, CYP3A4 |
2.72821 |
|
[BP] GO:0070989 |
oxidative demethylation
|
CYP1A2, CYP2D6, CYP3A4 |
2.72821 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
2.72821 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
2.71974 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, HIF1A, MET, SMAD3, SRC |
2.7041 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, RORC |
2.6978 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
ALOX12, APP, AXL, BCL2, CA2, CYP1B1, DRD2, ESRRB, F3, HIF1A, HMGCR, IDO1, INSR, KDR, PIM1, PTGS2, SMAD3, SRC, TEK, TERT |
2.68383 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
2.66525 |
|
[BP] GO:0045913 |
None
|
ESRRB, HIF1A, INSR, PPARA, SRC |
2.65677 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR |
2.64497 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HIF1A, HSD17B2, INSR, PTGS2, SRC |
2.63331 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.63132 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.63132 |
|
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.63132 |
|
[BP] GO:0001516 |
None
|
MIF, PTGS1, PTGS2 |
2.63132 |
|
[BP] GO:0060158 |
None
|
DRD1, DRD2, DRD5 |
2.63132 |
|
[BP] GO:0046457 |
None
|
MIF, PTGS1, PTGS2 |
2.63132 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, DYRK1A, GSK3B, SRC, TNKS |
2.62414 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, DRD2, DRD3, EGFR, GSK3B, HCAR2, HIF1A, HMGCR, MIF, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.60971 |
|
[BP] GO:0042737 |
drug catabolic process
|
ACHE, CYP1A2, CYP2A6, CYP2D6, CYP3A4, DAO |
2.6035 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, GBA, PPARA, SMAD3, TEK |
2.58314 |
|
[BP] GO:1900543 |
None
|
DRD2, DRD3, GRM3, GRM8, PPARA |
2.57847 |
|
[BP] GO:0022898 |
None
|
ABCB1, APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9 |
2.57847 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, BCL2, CSNK2A1, DRD1, DRD2, DRD3, EGFR, GRIK5, GSK3B, HIF1A, HMGCR, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.57701 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, APP, CA2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, INSR, PIK3CA, PIK3CB, SRC |
2.57701 |
|
[BP] GO:0043086 |
negative regulation of catalytic activity
|
APP, CSNK2A1, DRD2, DRD3, DRD5, DUSP3, FABP4, GBA, GRM3, GSK3B, HMGCR, IGF1R, MMP9, PTGS2, PTPN1, SRC |
2.56759 |
|
[BP] GO:0030814 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8 |
2.56759 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3 |
2.56584 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
CSNK2A1, ESRRB, GBA, GSK3B, HIF1A, HSPA1A, INSR, KDR, PIK3CB, PPARA, PTPN1 |
2.56559 |
|
[BP] GO:0010628 |
positive regulation of gene expression
|
APP, DNMT1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, GSK3B, HIF1A, HSPA1A, INSR, MET, MMP12, NR3C1, PIK3CB, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.55902 |
|
[BP] GO:0045980 |
None
|
DRD2, DRD3, GRM3, GRM8, PPARA |
2.55902 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.55902 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, MIF, PTPN1, SRC |
2.55111 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CYP1A1, HMGCR, MIF, PTGS2, TERT |
2.55111 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, BCL2, CDK6, CYP1B1, DRD2, FABP3, HSPA1A, IDO1, PTGS2, SMAD3, TERT, XDH |
2.55082 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.55082 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.55082 |
|
[BP] GO:0019377 |
None
|
FUCA1, GBA, GBA2 |
2.55082 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.53498 |
|
[BP] GO:0014075 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.53498 |
|
[BP] GO:0001817 |
regulation of cytokine production
|
AXL, CYP1B1, DRD2, GBA, HIF1A, HSPA1A, IDO1, MIF, MMP12, PTGS2, PTPRS, SMAD3, SRC |
2.52845 |
|
[BP] GO:0030802 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8 |
2.52576 |
|
[BP] GO:0044242 |
None
|
AKR1B10, CYP1B1, FABP3, FABP4, FUCA1, GBA, GBA2 |
2.52376 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HMGCR, MIF, MMP12, SRC |
2.52376 |
|
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, ALOX15, APEX1, AXL, BCL2, CA2, CA9, CYP1B1, EGFR, GBA, GSK3B, HIF1A, HSPA1A, MIF, MMP9, NUAK1, PTGS2, PTPN1, SRC, TERT, TOP2A, TRPV1 |
2.51346 |
|
[BP] GO:0050714 |
None
|
ACHE, DRD2, EGFR, HCAR2, HIF1A, MIF, MMP12, SRC |
2.51345 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, GSK3B, HIF1A, INSR, PPARA, RORC, SRC |
2.51051 |
|
[BP] GO:0097756 |
None
|
ADORA1, DRD5, HMGCR, PTGS2 |
2.49788 |
|
[BP] GO:0010675 |
None
|
ESRRB, GSK3B, INSR, PPARA, RORC, SRC |
2.49186 |
|
[BP] GO:0007267 |
None
|
ADORA1, DRD1, DRD2, DRD3, DRD5, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, SLC1A1, TEK |
2.48259 |
|
[BP] GO:0051093 |
None
|
APP, BCL2, CDK6, DRD3, EGFR, ESRRB, GSK3B, HIF1A, MIF, PPARA, PTPRS, SMAD3, TEK, TERT, TRPV1, XDH |
2.47852 |
|
[BP] GO:0043467 |
regulation of generation of precursor metabolites and energy
|
ESRRB, GSK3B, HIF1A, INSR, PIK3CA, PPARA |
2.47593 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.47318 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, PPARA, PTGS2, SRC, TEK |
2.45783 |
|
[BP] GO:1901654 |
None
|
AKR1B1, CA9, CSNK2A1, EGFR, GBA, NR3C1, SRC |
2.45718 |
|
[BP] GO:0042060 |
None
|
ALOX15, DRD5, EGFR, PPARA, SMAD3 |
2.44719 |
|
[BP] GO:0097746 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, PTGS2 |
2.44145 |
|
[BP] GO:0035296 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, PTGS2 |
2.44145 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.43796 |
|
[BP] GO:0032409 |
None
|
ABCB1, APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9 |
2.43796 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
APP, BCL2, DRD2, DRD3, INSR, PIK3CA, PIM1, PTPRS, TNKS2 |
2.43584 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, DYRK1A, GSK3B, TNKS |
2.42505 |
|
[BP] GO:0009268 |
None
|
CA2, GBA, SRC, TRPV1 |
2.42464 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.42211 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, GRM1, INSR, PIK3CA, PIK3CB, PTPN1, SRC |
2.41559 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.41559 |
|
[BP] GO:0009822 |
alkaloid catabolic process
|
CYP2D6, CYP3A4 |
2.41559 |
|
[BP] GO:0000023 |
None
|
GAA, MGAM |
2.41559 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.41559 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.41559 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.41559 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.41518 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.40828 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.40828 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.40828 |
|
[BP] GO:0048546 |
None
|
BCL2, EGFR, HIF1A |
2.40828 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, KDR, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.40216 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, GRIK5, HCAR2, HIF1A, HMGCR, MIF, MMP12, SRC, TRPV1 |
2.39735 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, DYRK1A, GSK3B, SRC, TNKS |
2.39131 |
|
[BP] GO:1900371 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8 |
2.36917 |
|
[BP] GO:0001819 |
positive regulation of cytokine production
|
CYP1B1, DRD2, HIF1A, HSPA1A, IDO1, MIF, MMP12, PTGS2, SMAD3, SRC |
2.36865 |
|
[BP] GO:0031331 |
positive regulation of cellular catabolic process
|
ESRRB, GBA, GSK3B, HIF1A, HSPA1A, INSR, KDR, PIK3CB, PPARA, PTPN1 |
2.36865 |
|
[BP] GO:0032963 |
collagen metabolic process
|
HIF1A, MMP1, MMP12, MMP2, MMP9 |
2.36865 |
|
[BP] GO:0001961 |
None
|
AXL, HIF1A, HSPA1A, MMP12 |
2.36499 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.36499 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PTGS2, SMAD3, SRC, TERT |
2.35724 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTGS2, TEK, TRPV1, TYR |
2.35724 |
|
[BP] GO:0030808 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8 |
2.35724 |
|
[BP] GO:0034097 |
response to cytokine
|
ALOX15, AXL, BCL2, FABP4, FLT3, GBA, GSK3B, HIF1A, PTGS2, SRC, TRPV1 |
2.35215 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DNMT1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC |
2.35127 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.35127 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.35127 |
|
[BP] GO:0033135 |
regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.34324 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ACHE, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FLT3, FUCA1, FUT7, GBA, GBA2, GLO1, GSK3B, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.34228 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.34099 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, ALOX12, DRD2, F10, F3, GBA, HIF1A, MET, XDH |
2.33629 |
|
[BP] GO:0030818 |
None
|
DRD2, DRD3, GRM3, GRM8 |
2.33629 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, HIF1A, IDO1, PTGS2 |
2.33128 |
|
[BP] GO:0050880 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, PTGS2 |
2.33007 |
|
[BP] GO:0046903 |
None
|
ALOX5, APP, AXL, CA2, CA9, DRD2, DRD3, FUCA1, GAA, HIF1A, HSPA1A, MGAM, MIF, MMP9, SLC1A1, TRPV1, XDH |
2.32488 |
|
[BP] GO:0035150 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, PTGS2 |
2.3135 |
|
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.30948 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, HIF1A, KDR, MMP2, PIK3CA, PIK3CB, PTGS2, TEK |
2.30885 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, FABP3, FABP4, MET, PIK3CA, PIK3CB |
2.30702 |
|
[BP] GO:0045761 |
None
|
DRD2, DRD3, DRD5, GRM3 |
2.30484 |
|
[BP] GO:0097366 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.30484 |
|
[BP] GO:0051254 |
None
|
APP, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HIF1A, HSPA1A, INSR, MET, MMP12, NR3C1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.29075 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, DYRK1A, GSK3B, TNKS |
2.29075 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
HIF1A, KDR, MET, PTGS2, TEK |
2.29075 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CYP1A1, EGFR, HMGCR, PTGS2, TRPV1, TYR |
2.2875 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, F3, HIF1A, KDR, MMP12, SMAD3, TEK, XDH |
2.28646 |
|
[BP] GO:0045596 |
None
|
APP, BCL2, CDK6, DRD3, EGFR, ESRRB, GSK3B, PPARA, PTPRS, SMAD3, TERT, TRPV1, XDH |
2.28267 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
ALOX12, CYP1B1, F3, HIF1A, KDR, PTGS2, TEK, TERT, XDH |
2.27833 |
|
[BP] GO:0045821 |
None
|
ESRRB, HIF1A, INSR |
2.27833 |
|
[BP] GO:0090342 |
None
|
CDK6, MIF, NUAK1, TERT |
2.27431 |
|
[BP] GO:0030803 |
None
|
DRD2, DRD3, GRM3, GRM8 |
2.27431 |
|
[BP] GO:0006633 |
None
|
ALOX12, ALOX15, MIF, PTGS1, PTGS2 |
2.27431 |
|
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
HIF1A, MMP1, MMP12, MMP2, MMP9 |
2.27431 |
|
[BP] GO:0007200 |
None
|
DRD1, DRD2, DRD5, ESR1, GRM5 |
2.25267 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
ALOX12, APP, AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, SRC, TEK, TUBB3 |
2.25024 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, EGFR, HCAR2, MET, PIK3CA, PPARA, SMAD3 |
2.24441 |
|
[BP] GO:0060760 |
None
|
AXL, HIF1A, HSPA1A, MMP12 |
2.24432 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, DRD2, DRD3, GPR35, GSK3B, HMGCR, HSPA1A, MMP9, PTGS2 |
2.24063 |
|
[BP] GO:0006091 |
generation of precursor metabolites and energy
|
AKR1B1, AOX1, CYP19A1, CYP1A2, GAA, GSK3B, IDO1, NQO2, XDH |
2.23948 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF |
2.22599 |
|
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.22107 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.22107 |
|
[BP] GO:0007617 |
None
|
APP, DRD1, DRD5 |
2.22107 |
|
[BP] GO:0051197 |
None
|
ESRRB, HIF1A, INSR |
2.22107 |
|
[BP] GO:0046394 |
None
|
ALOX12, ALOX15, ALOX5, CYP1A1, IDO1, MIF, PTGS1, PTGS2 |
2.21949 |
|
[BP] GO:0030815 |
None
|
DRD2, DRD3, GRM3, GRM8 |
2.21822 |
|
[BP] GO:0046165 |
None
|
AKR1B1, CYP3A4, FDPS, GBA, HMGCR |
2.21822 |
|
[BP] GO:0016053 |
None
|
ALOX12, ALOX15, ALOX5, CYP1A1, IDO1, MIF, PTGS1, PTGS2 |
2.21103 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, GRIK5, HCAR2, HIF1A, HMGCR, MIF, MMP12, SRC |
2.19049 |
|
[BP] GO:0030799 |
None
|
DRD1, DRD2, DRD3, DRD5, GRM3, GRM8 |
2.18879 |
|
[BP] GO:1900372 |
None
|
DRD2, DRD3, GRM3, GRM8 |
2.1874 |
|
[BP] GO:0030809 |
None
|
DRD2, DRD3, GRM3, GRM8 |
2.1874 |
|
[BP] GO:0045936 |
None
|
DRD2, DRD3, DUSP3, FABP4, GBA, GRM3, GRM8, HMGCR, IGF1R, PPARA, PTPN1, XDH |
2.1843 |
|
[BP] GO:0010563 |
None
|
DRD2, DRD3, DUSP3, FABP4, GBA, GRM3, GRM8, HMGCR, IGF1R, PPARA, PTPN1, XDH |
2.18159 |
|
[BP] GO:0098908 |
None
|
GBA, GPR35 |
2.18159 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.18159 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.18159 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.18159 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.18159 |
|
[BP] GO:0050708 |
None
|
ACHE, DRD2, DRD3, EGFR, HCAR2, HIF1A, HMGCR, MIF, MMP12, SRC |
2.17613 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3 |
2.17177 |
|
[BP] GO:0001892 |
None
|
EGFR, ESRRB, HIF1A |
2.17177 |
|
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.17177 |
|
[BP] GO:0030800 |
None
|
DRD2, DRD3, GRM3, GRM8 |
2.16664 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, RORC |
2.16603 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, ESRRB, GBA, GSK3B, HIF1A, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PTPN1 |
2.16603 |
|
[BP] GO:0045893 |
None
|
APP, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HIF1A, INSR, MET, MMP12, NR3C1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.16603 |
|
[BP] GO:1903508 |
None
|
APP, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HIF1A, INSR, MET, MMP12, NR3C1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.16603 |
|
[BP] GO:1902680 |
None
|
APP, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HIF1A, INSR, MET, MMP12, NR3C1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.1626 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.1556 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PTGS2, TEK, TRPV1, TYR |
2.14258 |
|
[BP] GO:0006066 |
None
|
AKR1B1, AKR1B10, APP, CYP1B1, CYP3A4, FDPS, GBA, HMGCR |
2.13512 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, FLT3, GRM1, INSR, MIF, PIK3CB, PTPN1, SRC |
2.1303 |
|
[BP] GO:0023052 |
None
|
ADORA1, DRD1, DRD2, DRD3, DRD5, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, SLC1A1, TEK |
2.11547 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.11547 |
|
[BP] GO:0051968 |
None
|
DRD1, EGFR, PTGS2 |
2.11547 |
|
[BP] GO:0042749 |
None
|
ADORA1, DRD2, DRD3 |
2.11547 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, SRC |
2.10911 |
|
[BP] GO:0070848 |
response to growth factor
|
APP, EGFR, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.10776 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, MIF, PIK3CA, PIK3CB, PTGS1, PTGS2, TRPV1 |
2.10157 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
BCL2, CA2, CA9, EGFR, ESR1, HIF1A, MET, SMAD3, SRC |
2.09975 |
|
[BP] GO:2000146 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF |
2.09975 |
|
[BP] GO:0003014 |
None
|
ADORA1, AKR1B1, BCL2, DRD2, HSD11B2 |
2.09422 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, DRD2, EGFR, HCAR2, HIF1A, MIF, MMP12, SRC |
2.09241 |
|
[BP] GO:0070228 |
regulation of lymphocyte apoptotic process
|
AURKB, HIF1A, IDO1, MIF |
2.08315 |
|
[BP] GO:0048146 |
positive regulation of fibroblast proliferation
|
CDK6, EGFR, ESR1, MIF |
2.08315 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.08315 |
|
[BP] GO:0034762 |
None
|
ABCB1, APP, BCL2, CA2, DRD1, DRD2, DRD3, GPR35, GRM5, MMP9 |
2.07483 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DNMT1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, GSK3B, HIF1A, IGF1R, INSR, KDR, MET, NR3C1, NUAK1, PIK3CA, PIM1, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.06738 |
|
[BP] GO:0090344 |
None
|
CDK6, MIF, TERT |
2.0653 |
|
[BP] GO:1902895 |
None
|
HIF1A, SMAD3, TERT |
2.0653 |
|
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
MMP2, MMP9, TERT |
2.0653 |
|
[BP] GO:0051194 |
None
|
ESRRB, HIF1A, INSR |
2.0653 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.0653 |
|
[BP] GO:0033561 |
regulation of water loss via skin
|
ALOX12, GBA, MET |
2.0653 |
|
[BP] GO:0035239 |
tube morphogenesis
|
BCL2, EGFR, ESR1, HIF1A, MET, SMAD3, SRC |
2.06035 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
HIF1A, KDR, MET, MMP9, PTGS2, SRC, TEK |
2.06035 |
|
[BP] GO:0032872 |
regulation of stress-activated MAPK cascade
|
APP, DUSP3, EGFR, HMGCR, IGF1R, PTPN1, XDH |
2.06035 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.05956 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.05956 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, SMAD3, TRPV1 |
2.05956 |
|
[BP] GO:0070302 |
regulation of stress-activated protein kinase signaling cascade
|
APP, DUSP3, EGFR, HMGCR, IGF1R, PTPN1, XDH |
2.05054 |
|
[BP] GO:0032922 |
None
|
DRD2, DRD3, PPARA, RORC |
2.03113 |
|
[BP] GO:0051100 |
negative regulation of binding
|
AURKB, CYP2D6, GSK3B, MET, PPARA, TNKS |
2.02403 |
|
[BP] GO:0030100 |
regulation of endocytosis
|
ALOX15, APP, AXL, DRD2, PIK3CB, PTPN1, SRC |
2.01668 |
|
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, APEX1, APP, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GRM3, GRM5, GRM8, GSK3B, HIF1A, HSPA1A, IGF1R, INSR, MET, MMP12, NR3C1, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.01544 |
|
[BP] GO:2000209 |
regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.01544 |
|
[BP] GO:0044062 |
None
|
ADORA1, DRD2, DRD3 |
2.01544 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.01544 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, GSK3B, HIF1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.01459 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.01103 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.01103 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.01103 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.01103 |
|
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, MMP9, TERT |
2.00802 |
|
[BP] GO:1900180 |
regulation of protein localization to nucleus
|
APP, EGFR, GSK3B, PTGS2, SMAD3, SRC, TERT |
2.00744 |
|
[BP] GO:0021853 |
None
|
DRD1, DRD2 |
2.00744 |
|
[BP] GO:0099565 |
chemical synaptic transmission, postsynaptic
|
DRD2, GSK3B |
2.00744 |
|
[BP] GO:0043696 |
None
|
CDK6, ESRRB |
2.00744 |
|
[BP] GO:0043697 |
None
|
CDK6, ESRRB |
2.00744 |
|
[BP] GO:0006678 |
None
|
GBA, GBA2 |
2.00744 |
|
[BP] GO:0010641 |
None
|
F3, SRC |
2.00744 |
|
[BP] GO:0090325 |
None
|
DRD2, DRD3 |
2.00744 |
|
[BP] GO:0007598 |
None
|
F10, F3 |
2.00744 |
|
[BP] GO:1904936 |
None
|
DRD1, DRD2 |
2.00744 |
|
[BP] GO:0051122 |
hepoxilin biosynthetic process
|
ALOX12, ALOX15 |
2.00744 |
|
[BP] GO:0051121 |
hepoxilin metabolic process
|
ALOX12, ALOX15 |
2.00744 |
|
[BP] GO:0042321 |
None
|
ADORA1, DRD2 |
2.00744 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, DRD2, DUSP3, ESR1, HSPA1A, IDO1, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PTPN1, PTPRS, SMAD3, SRC |
2.00238 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ADORA1, CA2, CA4, CA9, DRD1, DRD2, DRD5, EGFR, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, INSR, MET, MGAM, PTGS2, SLC1A1, SRC, TEK, TRPV1 |
6.41775 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX12, ALOX15, ALPL, APP, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FLT3, GAA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, IGF1R, INSR, KDR, MET, MGAM, MMP2, PIK3CA, PIK3CB, PIM1, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TEK, TERT, TRPV1 |
6.3094 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX12, ALOX15, ALOX5, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FLT3, FUT7, GAA, GBA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, IGF1R, INSR, KDR, MET, MGAM, MMP2, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, TYR |
6.18824 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, APP, AURKB, BACE1, BCL2, CA1, CA2, CA4, CA7, CBR1, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GRIA2, GRIA4, GRIK5, GSK3B, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, INSR, KDR, MGAM, MIF, MMP2, MMP9, NQO2, NR3C1, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.49363 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CBR1, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM5, GSK3B, HIF1A, HMGCR, HSPA1A, IGF1R, INSR, KDR, MGAM, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
5.28742 |
|
[CC] GO:0043226 |
organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA9, CBR1, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM3, GRM5, GSK3B, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MGAM, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
5.18669 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, BACE1, CA4, DRD1, DRD2, DRD3, DRD5, F10, F3, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, PTPRS, SLC1A1, TEK, TRPV1 |
5.05274 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BACE1, BCL2, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, EGFR, F10, FLT3, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGS1, PTGS2, PTPN1 |
4.96057 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ADORA1, ADORA3, ALOX15, APP, AXL, BACE1, CA2, CA4, CA9, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, F10, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MGAM, PTGS2, PTPRS, SLC1A1, SRC, TEK, TRPV1 |
4.88098 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
4.12272 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, EGFR, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGS1, PTGS2 |
3.9148 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, BACE1, DRD1, DRD2, DRD3, DRD5, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, PTPRS, SLC1A1, TEK, TRPV1 |
3.87324 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, IGF1R, INSR, KDR, MET, MGAM, PIK3CA, PIK3CB, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SRC, TEK, TRPV1, TYR |
3.79005 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HIF1A, PIK3CA, PTGS2, PTPRS, SRC, TEK, TUBB3 |
3.50139 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, DRD1, DRD2, DRD5, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HIF1A, PIK3CA, PTGS2, PTPRS, SRC, TEK, TUBB3 |
3.37337 |
|
[CC] GO:0044422 |
organelle part
|
AKR1B1, ALOX5, AOX1, APEX1, APP, AURKB, BACE1, BCL2, CA4, CA9, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GRIA2, GRIA4, GSK3B, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSPA1A, IDO1, INSR, MGAM, MIF, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR |
3.20758 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, PTPRS, SRC, TRPV1 |
3.10893 |
|
[CC] GO:0042734 |
None
|
GRIK5, GRM1, GRM3, GRM5, GRM8 |
2.81273 |
|
[CC] GO:0098794 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3, GSK3B |
2.80657 |
|
[CC] GO:0031090 |
None
|
ALOX5, APP, BACE1, BCL2, CA4, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DRD1, DRD2, DRD5, EGFR, FUT7, GAA, GBA, GBA2, GRIA2, GRIA4, HMGCR, INSR, MGAM, PTGS1, PTGS2, SMAD3, SRC, TNKS, TNKS2, TYR |
2.80556 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CES2, CYP19A1, CYP2D6, FLT3, GBA2, GRIK5, HMGCR, HSPA1A, KDR, PTGS2, PTPN1, XDH |
2.76279 |
|
[CC] GO:0044446 |
intracellular organelle part
|
AKR1B1, ALOX5, AOX1, APEX1, APP, AURKB, BACE1, BCL2, CA4, CA9, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GRIA2, GRIA4, GSK3B, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSPA1A, INSR, MGAM, MIF, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR |
2.71974 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, BACE1, CA2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, IDO1, INSR, PTGS1, PTGS2, PTPRS, SRC, TRPV1, TUBB3 |
2.56584 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, BACE1, CA2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PTGS2, PTPRS, SRC, TUBB3 |
2.55575 |
|
[CC] GO:0043197 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.54071 |
|
[CC] GO:0031982 |
None
|
ABCB1, AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APP, AXL, BACE1, CA1, CA2, CA4, CBR1, DRD2, DRD3, DUSP3, EGFR, F3, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GRIA4, GRM5, HSPA1A, INSR, KDR, MGAM, MIF, MMP9, NQO2, PTGS1, PTPN1, PTPRS, SLC1A1, SRC, TUBB3, TYR |
2.52576 |
|
[CC] GO:0044309 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.5103 |
|
[CC] GO:1903561 |
None
|
ABCB1, AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CBR1, DUSP3, F3, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GRIA4, GRM5, HSPA1A, INSR, MGAM, MIF, MMP9, NQO2, PTGS1, PTPRS, SLC1A1, SRC, TUBB3 |
2.48905 |
|
[CC] GO:0043230 |
None
|
ABCB1, AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CBR1, DUSP3, F3, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GRIA4, GRM5, HSPA1A, INSR, MGAM, MIF, MMP9, NQO2, PTGS1, PTPRS, SLC1A1, SRC, TUBB3 |
2.48809 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, DRD1, DRD2, DRD5, INSR, SRC, TRPV1 |
2.40828 |
|
[CC] GO:0043235 |
receptor complex
|
APP, EGFR, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, SMAD3 |
2.35127 |
|
[CC] GO:0044463 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, DRD1, DRD2, DRD5, GRIA2, GRIA4, GRIK5, GRM3, HIF1A, INSR, PTGS1, SRC, TRPV1 |
2.27431 |
|
[CC] GO:0120038 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, DRD1, DRD2, DRD5, GRIA2, GRIA4, GRIK5, GRM3, HIF1A, INSR, PTGS1, SRC, TRPV1 |
2.27431 |
|
[CC] GO:0070062 |
None
|
ABCB1, AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CBR1, DUSP3, F3, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GRM5, HSPA1A, INSR, MGAM, MIF, MMP9, NQO2, PTGS1, PTPRS, SLC1A1, SRC, TUBB3 |
2.27413 |
|
[CC] GO:0014069 |
None
|
ADORA1, DRD2, GRIK5, GRM1, GRM3, GRM5, SRC |
2.23259 |
|
[CC] GO:0099572 |
None
|
ADORA1, DRD2, GRIK5, GRM1, GRM3, GRM5, SRC |
2.23259 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.17177 |
|
[CC] GO:0097060 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, TRPV1 |
2.04038 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DUSP3, DYRK1A, EGFR, F10, F3, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, PTPRS, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
17.226 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, PIM1, PPARA, PTPN1, RORC, SMAD3, TNKS, TYR, XDH |
16.6477 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ACHE, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, GLO1, GSK3B, HMGCR, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
15.8143 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, NQO2, PTGS1, PTGS2, TYR, XDH |
11.792 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
9.20777 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4 |
9.15465 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DRD3, DRD5, ESR1, ESR2, ESRRA, ESRRB, F10, FDPS, GLO1, IDO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
8.99837 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ACHE, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, SRC, TEK, TOP2A, TRPV1 |
8.61323 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, PPARA, RORC, TEK, TRPV1 |
8.53387 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, XDH |
8.47654 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, IDO1, PTGS1, PTGS2, SRC |
8.42121 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, IDO1, PTGS1, PTGS2, SRC |
8.0767 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4 |
7.93503 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, HMGCR, HSD11B2, HSD17B1, IDO1, NQO2, PTGS1, PTGS2, SRC, XDH |
7.85695 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CDK6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, PPARA, RORC, TEK, TRPV1 |
7.62282 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.44 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, PPARA, RORC, TEK, TRPV1 |
7.34188 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA7, CA9, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, PPARA, PTPN1, RORC, SMAD3, TNKS |
7.18823 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, ESR1, ESR2, ESRRA, ESRRB, F10, FDPS, GLO1, IDO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.95806 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, NR3C1, PPARA, RORC, SMAD3, TEK, TRPV1 |
6.95276 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, PTGS1, PTGS2, TYR |
6.47211 |
|
[MF] GO:0005496 |
steroid binding
|
CYP3A4, ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, NR3C1, RORC |
6.47167 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.31532 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, TYR |
6.12851 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4 |
5.94391 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.94391 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
5.71912 |
|
[MF] GO:0030594 |
None
|
DRD1, DRD2, DRD3, DRD5, GRIA2, GRIA4, GRIK5, GRM1, GRM5 |
5.65315 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
5.56221 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
5.39781 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6, CYP3A4 |
5.30003 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, RORC |
5.22181 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, TEK, TRPV1 |
5.1884 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, TEK, TRPV1 |
5.1884 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.92561 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ADORA1, AOX1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FDPS, FLT3, GSK3B, HIF1A, HMGCR, HSD11B2, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TUBB3, XDH |
4.63932 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, SRC, TEK |
4.5903 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, SLC1A1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.5891 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB |
4.50296 |
|
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX12, ALOX15, ALOX5, IDO1, PTGS2 |
4.48197 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.45617 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.45617 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, HSD11B2, HSD17B1, NR3C1, PPARA, RORC, TRPV1 |
4.4165 |
|
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX12, ALOX15, ALOX5, IDO1, PTGS2 |
4.40834 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ALOX15, AOX1, APP, AURKB, AXL, CDK6, CSNK2A1, DAO, DYRK1A, EGFR, F10, F3, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PTPRS, SLC1A1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.37751 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.3735 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.35528 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR, NQO2, NR3C1 |
4.27215 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
4.22588 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.22548 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.13284 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.12985 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, GLO1 |
3.98844 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, APP, BCL2, CSNK2A1, DRD2, DYRK1A, EGFR, ESR1, ESR2, FLT3, GRIK5, HMGCR, IGF1R, KDR, MET, MIF, MMP9, NQO2, PTGS2, SMAD3, TERT, TOP2A, TRPV1, TYR, XDH |
3.81645 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
3.74635 |
|
[MF] GO:0019899 |
enzyme binding
|
APP, AURKB, BACE1, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, GRM5, GSK3B, HIF1A, HMGCR, HSPA1A, MET, MIF, NR3C1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.66356 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
3.65154 |
|
[MF] GO:1901338 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.50856 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ADORA1, AOX1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FDPS, FLT3, GSK3B, HIF1A, HMGCR, HSD11B2, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TUBB3, XDH |
3.43562 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TERT |
3.38055 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, GSK3B, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
3.21773 |
|
[MF] GO:0051213 |
dioxygenase activity
|
ALOX12, ALOX15, ALOX5, IDO1, PTGS1, PTGS2 |
3.09115 |
|
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
3.07281 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.07281 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.02969 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.91535 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.79965 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.79965 |
|
[MF] GO:0047977 |
hepoxilin-epoxide hydrolase activity
|
ALOX12, ALOX15 |
2.79965 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.79965 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.79965 |
|
[MF] GO:0051879 |
Hsp90 protein binding
|
CSNK2A1, HIF1A, KDR, NR3C1 |
2.78099 |
|
[MF] GO:0031072 |
heat shock protein binding
|
ADORA1, CSNK2A1, HIF1A, HSPA1A, KDR, NR3C1 |
2.77447 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1 |
2.69903 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
2.63403 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1 |
2.56759 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.55575 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.55093 |
|
[MF] GO:0015926 |
None
|
GAA, GBA2, MGAM |
2.55082 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, DRD3, DRD5 |
2.54071 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1 |
2.54071 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.41559 |
|
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.41559 |
|
[MF] GO:0004052 |
arachidonate 12-lipoxygenase activity
|
ALOX12, ALOX15 |
2.41559 |
|
[MF] GO:0032450 |
None
|
GAA, MGAM |
2.41559 |
|
[MF] GO:0051120 |
hepoxilin A3 synthase activity
|
ALOX12, ALOX15 |
2.41559 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.41559 |
|
[MF] GO:0004348 |
None
|
GBA, GBA2 |
2.41559 |
|
[MF] GO:0016798 |
None
|
APEX1, FUCA1, GAA, GBA, GBA2, MGAM |
2.35724 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.33629 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, GRM5, GSK3B, HIF1A, NR3C1, PTPN1, SMAD3, SRC, TOP2A |
2.30874 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, GRM5, GSK3B, HIF1A, NR3C1, PTPN1, SMAD3, SRC, TOP2A |
2.26976 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.22107 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.22107 |
|
[MF] GO:0005231 |
None
|
GRIA2, GRIA4, GRIK5, TRPV1 |
2.21822 |
|
[MF] GO:0008134 |
transcription factor binding
|
APEX1, BCL2, ESR1, ESRRB, FLT3, GSK3B, HIF1A, PIM1, PPARA, SMAD3, SRC, TERT |
2.2013 |
|
[MF] GO:0001588 |
None
|
DRD1, DRD5 |
2.18159 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.18159 |
|
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.18159 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.18159 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.18159 |
|
[MF] GO:0004558 |
None
|
GAA, MGAM |
2.18159 |
|
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.18159 |
|
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.17177 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, BACE1, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, F10, F3, FLT3, GSK3B, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PTPN1, PTPRS, SRC, TEK |
2.10208 |
|
[MF] GO:0101020 |
estrogen 16-alpha-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.00744 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.00744 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.00744 |
