Prescription Description
| Prescription ID | TCMF4517 |
| Pinyin Name | Jiang Ya Dai Pao Cha |
| Chinese Name | 降压袋泡茶 |
| English Name | Jiang Ya Dai Pao Tea |
| Function Description | 头痛, 眩晕, 牙痛 |
| Indications | Vertigo disorder, Hypertension |
| Disease ICD-11 Category |
SD22 [Vertigo disorder (TM1), 眩晕 (TM1)
]; BA2Z [Hypotension, unspecified, 低血压，未特指的 ]; |
| Human Tissues Associated with Indication | Brain |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH2244 | Prunella vulgaris | 夏枯草 | TCMH2244 | ITSAH2424-14 |
| TCMH1199 | Cassia tora | 决明子 | TCMH1199 | GENG109-13 |
| TCMH263 | Fructus leonuri | 茺蔚子 | TCMH263 | |
| TCMH695 | Uncaria rhynchophylla | 钩藤 | TCMH695 | ITSAM939-14 |
| TCMH986 | Scutellaria baicalensis | 黄芩 | TCMH986 | ITSAP4211-14 |
| TCMH226 | Camellia sinensis | 茶叶 | TCMH226 | ITSAG2924-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT126 | TERT | Telomerase reverse transcriptase | Transferase | O14746 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
Showing 1 to 10 of 91 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1191 | Bacillus megaterium |
| TCMT1208 | Escherichia coli K12 |
| TCMT1212 | Verticillium dahliae |
| TCMT1213 | Neisseria gonorrhoeae |
Showing 1 to 10 of 57 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AXL, BCL2, CYP1B1, MMP9, SRC | 2.67996 |
| [BP] GO:0001503 | ossification | ALOX15, ALPL, BCL2, MMP2, MMP9 | 2.51936 |
| [BP] GO:0001659 | None | ADORA1, DRD1, DRD2 | 2.03632 |
| [BP] GO:0001666 | response to hypoxia | ADORA1, BCL2, CYP1A1, DRD2, MMP2, PPARA, SRC, TERT | 3.55213 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, EPHX2 | 3.80579 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADORA1, ADORA2A, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, FABP4, FLT3, IGF1R, KDR, MMP9, PTPN1, SRC, XDH | 3.26257 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ADORA1, ALOX15, APP, BCL2, CDC25B, DRD2, FLT3, KDR, MMP9, PTPN1, SRC, XDH | 2.51227 |
| [BP] GO:0001963 | None | ADORA2A, DRD1, DRD2 | 2.75948 |
| [BP] GO:0001973 | None | ADORA1, ADORA2A, ADORA3 | 3.37515 |
| [BP] GO:0001975 | None | ADORA2A, DRD1, DRD2 | 2.22773 |
Showing 1 to 10 of 287 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCB1 | 0.6507 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | FLT3, PIM1 | 1.3451 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, CSNK2A1, SRC, MET, IGF1R | 4.1418 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.5536 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | BCL2 | 0.4046 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | MMP2, BCL2, PIM1 | 1.7501 |
| Alcoholism_Homo sapiens_hsa05034 | ADORA2A, DRD1, DRD2 | 1.2744 |
| Alzheimer's disease_Homo sapiens_hsa05010 | BACE1, APP | 0.762 |
| Amphetamine addiction_Homo sapiens_hsa05031 | DRD1 | 0.5607 |
| AMPK signaling pathway_Homo sapiens_hsa04152 | IGF1R | 0.4323 |
Showing 1 to 10 of 128 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples