Prescription Description
| Prescription ID | TCMF2846 |
| Pinyin Name | Sang Bai Pi Tang |
| Chinese Name | 桑白皮汤 |
| English Name | Sang Bai Pi Decoction |
| Function Description | 治肺气有余, 火炎痰盛作喘 |
| Indications | Asthma |
| Disease ICD-11 Category |
CA23 [Asthma, 哮喘
]; |
| Human Tissues Associated with Indication | Lung |
| Reference | SATCM |
| Reference Book/link | http://www.satcm.gov.cn/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH2629 | Cortex mori radicis praeparata | 桑白皮 | TCMH2629 | |
| TCMH130 | Pinellia ternata | 半夏 | TCMH130 | GBVT1123-13, GBVY1693-14 |
| TCMH2047 | Fructus perillae | 苏子 | TCMH2047 | |
| TCMH2322 | Prunus armeniaca | 杏仁 | TCMH2322 | ITSAJ4486-14 |
| TCMH145 | Bulbus fritillariae | 贝母 | TCMH145 | |
| TCMH1856 | Gardenia jasminoides | 山栀 | TCMH1856 | ITSAJ4473-14 |
| TCMH986 | Scutellaria baicalensis | 黄芩 | TCMH986 | ITSAP4211-14 |
| TCMH972 | Coptis chinensis | 黄连 | TCMH972 | ITSAO4469-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT126 | TERT | Telomerase reverse transcriptase | Transferase | O14746 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
Showing 1 to 10 of 86 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1191 | Bacillus megaterium |
| TCMT1208 | Escherichia coli K12 |
| TCMT1212 | Verticillium dahliae |
| TCMT1214 | Enterococcus faecium |
Showing 1 to 10 of 64 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AXL, BCL2, CYP1B1, MMP9, SRC | 2.81448 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, DNMT1, FABP3, HSD17B2, KDR, MMP2, SRC | 2.40397 |
| [BP] GO:0001503 | ossification | ALOX15, ALPL, BCL2, MMP2, MMP9 | 2.6184 |
| [BP] GO:0001666 | response to hypoxia | ADORA1, BCL2, CYP1A1, MMP2, PPARA, SRC, TERT | 2.86701 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1 | 2.81983 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADORA1, ALOX15, APP, BCL2, DRD1, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, SRC, XDH | 2.02549 |
| [BP] GO:0002318 | myeloid progenitor cell differentiation | FLT3, KIT | 2.11951 |
| [BP] GO:0002320 | lymphoid progenitor cell differentiation | BCL2, FLT3, KIT | 3.17669 |
| [BP] GO:0002521 | leukocyte differentiation | AXL, BCL2, FLT3, FUT7, KIT, MMP9 | 2.05424 |
| [BP] GO:0006468 | protein phosphorylation | APP, AURKB, AXL, BCL2, CSNK2A1, DRD1, DYRK1A, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC, TNKS | 4.79917 |
Showing 1 to 10 of 247 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCB1 | 0.6747 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | FLT3, KIT, PIM1 | 2.4496 |
| Adherens junction_Homo sapiens_hsa04520 | CSNK2A1, SRC, MET, IGF1R | 3.2692 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.5825 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | BCL2 | 0.4342 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | MMP2, BCL2, PIM1, F3 | 2.8595 |
| Alcoholism_Homo sapiens_hsa05034 | DRD1 | 0.3903 |
| Alzheimer's disease_Homo sapiens_hsa05010 | BACE1, APP | 0.7905 |
| Amphetamine addiction_Homo sapiens_hsa05031 | DRD1 | 0.5952 |
| AMPK signaling pathway_Homo sapiens_hsa04152 | IGF1R | 0.4578 |
Showing 1 to 10 of 137 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples