Prescription Description
| Prescription ID | TCMF2304 |
| Pinyin Name | Gan Wei Bai He Tang |
| Chinese Name | 肝胃百合汤 |
| English Name | Liver and Stomach Bai He Decoction |
| Function Description | |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | |
| Reference | Chinese Classical Prescriptions |
| Reference Book/link | ISBN 7-5023-3930-2 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH228 | Bupleurum chinense | 柴胡 | TCMH228 | ITSAM2218-14 |
| TCMH986 | Scutellaria baicalensis | 黄芩 | TCMH986 | ITSAP4211-14 |
| TCMH1499 | Changium smyrnioides | 明党参 | TCMH1499 | |
| TCMH1632 | Taraxacum mongolicum | 蒲公英 | TCMH1632 | ITSAG679-14 |
| TCMH2208 | Lindera strychnifolia | 乌药 | TCMH2208 | |
| TCMH284 | Melia toosendan | 川楝子 | TCMH284 | KY197925 |
| TCMH2532 | Curcuma aromatica | 郁金 | TCMH2532 | ITSAF2298-14 |
| TCMH407 | Salvia miltiorrhiza | 丹参 | TCMH407 | ITSAH2408-14 |
| TCMH1525 | Crassostrea gigas | 牡蛎 | TCMH1525 | BCMOL364-12 |
| TCMH62 | Lilium brownii | 百合 | TCMH62 | ITSAO2415-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT126 | TERT | Telomerase reverse transcriptase | Transferase | O14746 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
Showing 1 to 10 of 134 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1168 | Trichomonas vaginalis |
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1191 | Bacillus megaterium |
| TCMT1208 | Escherichia coli K12 |
Showing 1 to 10 of 73 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, RELA, SRC | 3.82557 |
| [BP] GO:0000904 | cell morphogenesis involved in differentiation | AR, AXL, MET, SRC, TEK | 2.27561 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGES, RELA, SLC6A4, SRC | 3.67965 |
| [BP] GO:0001503 | ossification | ALOX15, ALPL, EGFR, MMP2, MMP9, TEK | 2.9666 |
| [BP] GO:0001505 | regulation of neurotransmitter levels | ACHE, CYP1B1, EGFR, INSR, MAOA, SLC6A2, SLC6A4, SMAD3 | 2.81727 |
| [BP] GO:0001666 | response to hypoxia | CYP1A1, MMP2, PPARA, SLC6A4, SMAD3, SRC, TEK, TERT | 2.77873 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2C19, PTGES | 5.432 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADRA2A, ALOX15, APP, AR, CDC25B, DUSP3, EGFR, FABP4, FLT3, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MMP9, PTPN1, SRC, TEK, XDH | 3.09925 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ADRA2A, ALOX15, APP, AR, CDC25B, EGFR, FLT3, INSR, KDR, MAP2K1, MAP3K7, MMP9, PTPN1, SRC, TEK, XDH | 3.37531 |
| [BP] GO:0002009 | morphogenesis of an epithelium | AR, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC | 2.5706 |
Showing 1 to 10 of 415 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCB1 | 0.6334 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | MAP2K1, FLT3, PIM1, RELA | 3.1445 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, SMAD3, CSNK2A1, SRC, INSR, MAP3K7, MET, EGFR, IGF1R | 8.6254 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA, RELA | 1.1659 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | CACNA1C | 0.3158 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | SMAD3, MMP2, PIM1, F3, RELA | 3.2782 |
| Alcoholism_Homo sapiens_hsa05034 | MAP2K1, MAOA | 0.6227 |
| Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | CACNA1C | 0.4551 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | INSR | 0.6682 |
| Alzheimer's disease_Homo sapiens_hsa05010 | APP, CACNA1C | 0.6558 |
Showing 1 to 10 of 183 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples