Prescription Description
| Prescription ID | TCMF2254 |
| Pinyin Name | Jia Wei Bai He Di Huang Tang |
| Chinese Name | 加味百合地黄汤 |
| English Name | Added Flavor BHDH Decoction |
| Function Description | |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | |
| Reference | Chinese Classical Prescriptions |
| Reference Book/link | ISBN 7-5023-3930-2 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH62 | Lilium brownii | 百合 | TCMH62 | ITSAO2415-14 |
| TCMH2573 | Ziziphus jujuba var. spinosa | 枣仁 | TCMH2573 | ITSAM943-14 |
| TCMH1896 | Radix rehmanniae | 生地黄 | TCMH1896 | |
| TCMH2681 | Caulis bambusae in taeniam | 竹茹 | TCMH2681 | |
| TCMH2554 | Polygala tenuifolia | 远志 | TCMH2554 | MF096619 |
| TCMH606 | Wolfiporia cocos | 茯苓 | TCMH606 | GBPOL314-13 |
| TCMH1321 | Os draconis | 龙骨 | TCMH1321 | |
| TCMH2532 | Curcuma aromatica | 郁金 | TCMH2532 | ITSAF2298-14 |
| TCMH2624 | Anemarrhena asphodeloides | 知母 | TCMH2624 | GBVA3255-11, GBVU1201-13 |
| TCMH628 | Glycyrrhiza uralensis | 甘草 | TCMH628 | ITSAM892-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
Showing 1 to 10 of 101 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1186 | Plasmodium yoelii yoelii |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1208 | Escherichia coli K12 |
| TCMT1209 | Staphylococcus haemolyticus |
Showing 1 to 10 of 64 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, APEX1, AXL, BCL2, CYP1B1, MMP9, RELA, SRC | 4.32529 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, FABP3, HSD17B2, KDR, MMP2, PTGES, RELA, SRC | 2.6458 |
| [BP] GO:0001932 | regulation of protein phosphorylation | APP, AR, BCL2, CDC25B, FABP4, FLT3, HMGCR, IGF1R, KDR, MAP2K1, MAP3K7, MMP9, PDE5A, PTPN1, SRC, XDH | 2.58868 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | APP, AR, BCL2, CDC25B, FLT3, HMGCR, KDR, MAP2K1, MAP3K7, MMP9, PDE5A, PTPN1, SRC, XDH | 3.07306 |
| [BP] GO:0002009 | morphogenesis of an epithelium | AR, BCL2, CA2, CA9, ESR1, MET, SRC | 2.22156 |
| [BP] GO:0002237 | response to molecule of bacterial origin | ALPL, AXL, CYP1A1, CYP1A2, MAOB, PTGES, RELA, SRC | 2.84291 |
| [BP] GO:0003006 | developmental process involved in reproduction | ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, ESR1, ESRRB, HSD17B2, HSD17B3, MAP2K1, SRC | 3.57745 |
| [BP] GO:0006081 | None | AKR1B10, CYP1B1, GLO1, RELA | 2.13919 |
| [BP] GO:0006145 | None | AOX1, XDH | 2.18081 |
| [BP] GO:0006352 | DNA-templated transcription, initiation | AR, ESR1, ESR2, ESRRA, ESRRB, PPARA | 2.1183 |
Showing 1 to 10 of 283 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| Acute myeloid leukemia_Homo sapiens_hsa05221 | MAP2K1, FLT3, PIM1, RELA | 3.3551 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, CSNK2A1, SRC, MAP3K7, MET, IGF1R | 5.2765 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA, RELA | 1.317 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | BCL2, CACNA1C | 0.8511 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | MMP2, BCL2, PIM1, F3, RELA | 3.5675 |
| Alcoholism_Homo sapiens_hsa05034 | MAP2K1, MAOB, MAOA | 1.317 |
| Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | CACNA1C | 0.543 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2 | 0.7523 |
| Alzheimer's disease_Homo sapiens_hsa05010 | APP, CACNA1C | 0.7881 |
| Amoebiasis_Homo sapiens_hsa05146 | RELA | 0.5098 |
Showing 1 to 10 of 178 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples