Prescription Description
| Prescription ID | TCMF1362 |
| Pinyin Name | Li Dan Pai Shi Pian |
| Chinese Name | 利胆排石片 |
| English Name | Lidan Paishi Tablets |
| Function Description | 用于胆道结石, 胆道感染, 胆囊炎 |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | Liver, Gallbladder |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH767 | Herba lysimachiae | 过路黄 | TCMH767 | |
| TCMH2494 | Artemisia capillaris | 茵陈蒿 | TCMH2494 | ITSAN1371-14 |
| TCMH986 | Scutellaria baicalensis | 黄芩 | TCMH986 | ITSAP4211-14 |
| TCMH1533 | Saussurea lappa | 木香 | TCMH1533 | |
| TCMH2532 | Curcuma aromatica | 郁金 | TCMH2532 | ITSAF2298-14 |
| TCMH363 | Rheum officinale | 大黄 | TCMH363 | ITSAJ4685-14 |
| TCMH182 | Areca catechu | 槟榔 | TCMH182 | ITSAA732-14 |
| TCMH2630 | Citrus aurantium | 枳实 | TCMH2630 | ITSAA1279-14 |
| TCMH1450 | Natrii sulfas | 芒硝 | TCMH1450 | |
| TCMH890 | Cortex magnoliae officinalis | 厚朴 | TCMH890 | ITSAM1591-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT114 | CNR2 | Cannabinoid CB2 receptor | GPCR | P34972 |
| TCMT115 | CNR1 | Cannabinoid CB1 receptor | GPCR | P21554 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
Showing 1 to 10 of 118 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1182 | Streptococcus sanguinis |
| TCMT1183 | Candida albicans SC5314 |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1191 | Bacillus megaterium |
Showing 1 to 10 of 75 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AKR1C3, AXL, BCL2, CYP1B1, MMP9, RELA, SRC | 3.95651 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, AKR1C3, FABP3, HSD17B2, KDR, MMP2, PTGES, PTGS2, RELA, SRC | 3.80088 |
| [BP] GO:0001503 | ossification | ALOX15, ALPL, BCL2, MMP2, MMP9 | 2.10592 |
| [BP] GO:0001516 | None | PTGES, PTGS1, PTGS2 | 2.78076 |
| [BP] GO:0001666 | response to hypoxia | BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SRC | 2.11786 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | AKR1C3, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, PTGES, PTGS1, PTGS2, TBXAS1 | 8.06106 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ALOX15, APP, AR, BCL2, FABP4, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, SRC, XDH | 3.7829 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ALOX15, APP, AR, BCL2, FLT3, HTR2A, HTR2B, HTR2C, KDR, KIT, MAP2K1, MAP3K7, MMP9, PIK3CA, PIK3CB, PTGS2, SRC, XDH | 4.74352 |
| [BP] GO:0002237 | response to molecule of bacterial origin | ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, PTGS2, RELA, SRC | 4.09286 |
| [BP] GO:0002318 | myeloid progenitor cell differentiation | FLT3, KIT | 2.01014 |
Showing 1 to 10 of 413 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCB1 | 0.683 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | MAP2K1, PIK3CA, FLT3, KIT, PIM1, PIK3CB, RELA | 7.2016 |
| Adherens junction_Homo sapiens_hsa04520 | CSNK2A1, SRC, MAP3K7, MET, IGF1R | 4.1431 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA, RELA | 1.2821 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | PIK3CA, BCL2, CACNA1C, PIK3CB | 2.1258 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | PIK3CA, MMP2, BCL2, PIM1, PIK3CB, F3, RELA | 5.6529 |
| Alcoholism_Homo sapiens_hsa05034 | MAP2K1, MAOA | 0.6753 |
| Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | CACNA1C | 0.4978 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2, PIK3CA, PIK3CB | 2.7854 |
| Alzheimer's disease_Homo sapiens_hsa05010 | APP, CACNA1C | 0.7093 |
Showing 1 to 10 of 179 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples