TCM-ID Component

Component: Codonopsis lanceolata 羊乳根

Description of the Component

Component ID	TCMH2439
Latin Name	Codonopsis lanceolata
English Name	Lance Asiabell Root
Chinese Pinyin Name	Yang Ru Gen
中文名	羊乳根
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	CFDA
Barcode ID	ITSAL4529-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx4212	Liao Fei Ning Tablets	疗肺宁片
TCMFx4563	Mu Ru Duo Granules	母乳多颗粒

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT101	PTPN1	Protein-tyrosine phosphatase 1B	Hydrolase	P18031
TCMT273	NR1H4	Bile acid receptor FXR	Nuclear receptor	Q96RI1

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1251	Candida albicans
TCMT1438	Plasmodium falciparum
TCMT1444	Fusarium oxysporum
TCMT1458	Filobasidiella neoformans

Ingredient Structrues

Ingredient ID: TCMC2680
Formula: C38H44O11

Common Name	n.a.
IUPAC Name	n.a.
Canonical SMILES	COC(=O)/C(=C/1C(=O)[C@H](O)[C@@]2(C3=C(C[C@@H]4[C@@]5([C@@H]13)OC(=O)C(=C5C[C@@H]1[C@]4(C)[C@@H]3C[C@@H]3[C@@]1(O)COC(=O)/C(=C/C)/C)COC(=O)C)[C@@H]1[C@H]2C1)C)/C
Standard InCHI	InChI=1S/C38H44O11/c1-8-15(2)32(42)48-14-37(45)24-11-23(24)35(5)25(37)12-22-20(13-47-17(4)39)34(44)49-38(22)26(35)10-19-18-9-21(18)36(6)28(19)29(38)27(30(40)31(36)41)16(3)33(43)46-7/h8,18,21,23-26,29,31,41,45H,9-14H2,1-7H3/b15-8+,27-16-/t18-,21-,23-,24+,25-,26+,29+,31+,35+,36+,37+,38+/m1/s1
Standard InCHIKey	WZKZSZYDBUUHLB-IBBKUXAASA-N
External Identifiers	ChEMBL [CHEMBL2229596]; PubChem [44207635];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2439	Codonopsis lanceolata	Yang Ru Gen	羊乳根
TCMH2117	Lepidium apetalum	Ting Li Zi	葶苈子
TCMH149	Lepidium apetalum	Bei Ting Li Zi	北葶苈子
TCMH2116	Lepidium apetalum	Ting Li Cao	葶苈草
TCMH2131	Codonopsis lanceolata	Tu Dang Shen	土党参

Ingredient ID: TCMC2678
Formula: C15H26O2

Common Name	5E,10(14)-Germacradien-1Beta,4Beta-Diol
IUPAC Name	(1S,4S,5E,7S)-4-methyl-10-methylidene-7-propan-2-ylcyclodec-5-ene-1,4-diol
Canonical SMILES	CC([C@@H]1CCC(=C)[C@@H](O)CC[C@](/C=C/1)(C)O)C
Standard InCHI	InChI=1S/C15H26O2/c1-11(2)13-6-5-12(3)14(16)8-10-15(4,17)9-7-13/h7,9,11,13-14,16-17H,3,5-6,8,10H2,1-2,4H3/b9-7+/t13-,14+,15-/m1/s1
Standard InCHIKey	NSIOXFVMCTYIOU-UVIYIIQCSA-N
External Identifiers	ChEMBL [CHEMBL513802]; PubChem [44567152];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2439	Codonopsis lanceolata	Yang Ru Gen	羊乳根
TCMH2117	Lepidium apetalum	Ting Li Zi	葶苈子
TCMH149	Lepidium apetalum	Bei Ting Li Zi	北葶苈子
TCMH2116	Lepidium apetalum	Ting Li Cao	葶苈草
TCMH2131	Codonopsis lanceolata	Tu Dang Shen	土党参

Ingredient ID: TCMC1366
Formula: C20H34O3

Common Name	Imbricatolic Acid
IUPAC Name	(1S,4aR,5S,8aR)-5-[(3S)-5-hydroxy-3-methylpentyl]-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid
Canonical SMILES	OCC[C@H](CC[C@H]1C(=C)CC[C@@H]2[C@]1(C)CCC[C@]2(C)C(=O)O)C
Standard InCHI	InChI=1S/C20H34O3/c1-14(10-13-21)6-8-16-15(2)7-9-17-19(16,3)11-5-12-20(17,4)18(22)23/h14,16-17,21H,2,5-13H2,1,3-4H3,(H,22,23)/t14-,16-,17+,19+,20-/m0/s1
Standard InCHIKey	NSRKLZRKJJQJLD-BEUFEYIVSA-N
External Identifiers	ChEMBL [CHEMBL2048004]; PubChem [70688370];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2439	Codonopsis lanceolata	Yang Ru Gen	羊乳根
TCMH2285	Asparagus officinalis	Xiao Bai Bu	小百部
TCMH2117	Lepidium apetalum	Ting Li Zi	葶苈子
TCMH2267	Periploca sepium	Xiang Jia Pi	香加皮
TCMH149	Lepidium apetalum	Bei Ting Li Zi	北葶苈子
TCMH2116	Lepidium apetalum	Ting Li Cao	葶苈草
TCMH1928	Asparagus officinalis	Shi Diao Bai	石刁柏
TCMH2131	Codonopsis lanceolata	Tu Dang Shen	土党参

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC1366	C20H34O3	Imbricatolic Acid	322.25	0.6174	3.33	5.568	3	2	57.53	11	2	23	1
TCMC2678	C15H26O2	5E,10(14)-Germacradien-1Beta,4Beta-Diol	238.19	0.7157	2.89	3.029	2	2	40.46	6	1	17	0
TCMC2680	C38H44O11		676.29	0.9177	4.43	1.375	11	2	162.73	18	8	49	1

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)