TCM-ID Component

Description of the Component

Component ID	TCMH2141
Latin Name	Pseudolarix amabilis
English Name	Chinese golden larch
Chinese Pinyin Name	Tu Jing Pi
中文名	åœŸè†çš®
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID	ITSAM1582-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx172	E Zhang Feng Yao Shui	é¹…æŽŒé£Žè¯æ°´
TCMFx3073	Fu Fang Tu Jin Pi Ding	å¤æ–¹åœŸæ§¿çš®é…Š
TCMFx6911	Gan Lin Xi Ji	ç”˜éœ–æ´—å‰‚
TCMF7082	Jie Er Yin Pao Teng Tablets	æ´å°”é˜´æ³¡è…¾ç‰‡
TCMF6977	Jie Er Yin Xi Oral Liquid	æ´å°”é˜´æ´—æ¶²
TCMFx6336	Xuan Ling Yao Decoction	ç™£çµè¯æ°´
TCMFx108	Xuan Ning Liniment	ç™£å®æ½å‰‚
TCMFx1189	Xuan Shi Solution	ç™£æ¹¿è¯æ°´
TCMFx6737	Zhi Yang Ding	æ¢ç—’é…Š

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1251	Candida albicans

Ingredient Structrues

Ingredient ID: TCMC7023
Formula: C22H28O6

Common Name	Pseudolaric Acid A
IUPAC Name	(2E,4E)-5-[(1R,7S,8S,9S)-7-acetyloxy-4,9-dimethyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-en-9-yl]-2-methylpenta-2,4-dienoic acid
Canonical SMILES	CC1=CC[C@@]23[C@@](CC1)(OC(=O)C)[C@@H](CC2)[C@](OC3=O)(C)/C=C/C=C(/C(=O)[O-])C
Standard InCHI	InChI=1S/C22H28O6/c1-14-7-11-21-12-9-17(22(21,13-8-14)27-16(3)23)20(4,28-19(21)26)10-5-6-15(2)18(24)25/h5-7,10,17H,8-9,11-13H2,1-4H3,(H,24,25)/p-1/b10-5+,15-6+/t17-,20-,21+,22-/m0/s1
Standard InCHIKey	GOHMRMDXUXWCDQ-DKECHREQSA-M
External Identifiers	ChEMBL [N/A]; PubChem [100921643];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2141	Pseudolarix amabilis	Tu Jing Pi	åœŸè†çš®

Ingredient ID: TCMC6981
Formula: C20H30O3

Common Name	Pseudolaric Acid D
IUPAC Name	(1S,4S,5S,9S,10S,13R)-5-(hydroxymethyl)-5,9-dimethyltetracyclo[11.2.1.01,10.04,9]hexadec-14-ene-14-carboxylic acid
Canonical SMILES	OC[C@@]1(C)CCC[C@@]2([C@@H]1CC[C@@]13[C@H]2CC[C@H](C3)C(=C1)C(=O)[O-])C
Standard InCHI	InChI=1S/C20H30O3/c1-18(12-21)7-3-8-19(2)15(18)6-9-20-10-13(4-5-16(19)20)14(11-20)17(22)23/h11,13,15-16,21H,3-10,12H2,1-2H3,(H,22,23)/p-1/t13-,15-,16+,18-,19-,20+/m1/s1
Standard InCHIKey	WUENWZUJMIZJPA-UBTCDGAASA-M
External Identifiers	ChEMBL [N/A]; PubChem [91895324];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2141	Pseudolarix amabilis	Tu Jing Pi	åœŸè†çš®

Ingredient ID: TCMC6707
Formula: C28H38O11

Common Name	Pseudolaric Acid A-O-Î’-D-Glucopyranoside
IUPAC Name	[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (2E,4E)-5-[(1R,7S,8S,9R)-7-acetyloxy-4,9-dimethyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-en-9-yl]-2-methylpenta-2,4-dienoate
Canonical SMILES	OC[C@H]1O[C@@H](OC(=O)/C(=C/C=C/[C@@]2(C)OC(=O)[C@]34[C@@]([C@H]2CC3)(CCC(=CC4)C)OC(=O)C)/C)[C@@H]([C@H]([C@@H]1O)O)O
Standard InCHI	InChI=1S/C28H38O11/c1-15-7-11-27-12-9-19(28(27,13-8-15)38-17(3)30)26(4,39-25(27)35)10-5-6-16(2)23(34)37-24-22(33)21(32)20(31)18(14-29)36-24/h5-7,10,18-22,24,29,31-33H,8-9,11-14H2,1-4H3/b10-5+,16-6+/t18-,19+,20-,21+,22-,24+,26-,27-,28+/m1/s1
Standard InCHIKey	IVYWRYGMQNKDQB-VHJBJYHKSA-N
External Identifiers	ChEMBL [CHEMBL523006]; PubChem [44566375];
Reference of Component-Ingredient Pair	24685503

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2141	Pseudolarix amabilis	Tu Jing Pi	åœŸè†çš®

Ingredient ID: TCMC6420
Formula: C31H48O6

Common Name	Pseudolarolide C
IUPAC Name	methyl 3-[(1S,2S,4'R,5R,6R,8S,11R,12R,13R,15S,17R)-5-(2-hydroxypropan-2-yl)-1,4',11,13-tetramethyl-5'-oxospiro[16-oxapentacyclo[9.7.0.02,8.06,8.012,17]octadecane-15,2'-oxolane]-6-yl]propanoate
Canonical SMILES	COC(=O)CC[C@@]12C[C@@]32CC[C@]2([C@@]([C@@H]3CC[C@H]1C(O)(C)C)(C)C[C@@H]1[C@@H]2[C@H](C)C[C@]2(O1)OC(=O)[C@@H](C2)C)C
Standard InCHI	InChI=1S/C31H48O6/c1-18-14-31(15-19(2)25(33)37-31)36-20-16-28(6)22-9-8-21(26(3,4)34)29(11-10-23(32)35-7)17-30(22,29)13-12-27(28,5)24(18)20/h18-22,24,34H,8-17H2,1-7H3/t18-,19-,20-,21+,22+,24+,27-,28+,29-,30+,31+/m1/s1
Standard InCHIKey	YBQWVVDWBNHYPN-SBKBIPNSSA-N
External Identifiers	ChEMBL [CHEMBL505034]; PubChem [21592338];
Reference of Component-Ingredient Pair	21728150

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2141	Pseudolarix amabilis	Tu Jing Pi	åœŸè†çš®

Ingredient ID: TCMC6069
Formula: C20H26O5

Common Name	Deacetylpseudolaric Acid A
IUPAC Name	(2E,4E)-5-[(1R,7S,8S,9R)-7-hydroxy-4,9-dimethyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-en-9-yl]-2-methylpenta-2,4-dienoic acid
Canonical SMILES	CC1=CC[C@@]23[C@@](CC1)(O)[C@H](CC2)[C@@](OC3=O)(C)/C=C/C=C(/C(=O)[O-])C
Standard InCHI	InChI=1S/C20H26O5/c1-13-6-10-19-11-8-15(20(19,24)12-7-13)18(3,25-17(19)23)9-4-5-14(2)16(21)22/h4-6,9,15,24H,7-8,10-12H2,1-3H3,(H,21,22)/p-1/b9-4+,14-5+/t15-,18-,19-,20+/m1/s1
Standard InCHIKey	MQOMHFMKUJFDBH-UNZAVUEUSA-M
External Identifiers	ChEMBL [N/A]; PubChem [13992645];
Reference of Component-Ingredient Pair	25322560

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2141	Pseudolarix amabilis	Tu Jing Pi	åœŸè†çš®

Ingredient ID: TCMC6068
Formula: C20H24O7

Common Name	Deacetylpseudolaric Acid C2
IUPAC Name	(1R,7S,8S,9R)-9-[(1E,3E)-4-carboxypenta-1,3-dienyl]-7-hydroxy-9-methyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylic acid
Canonical SMILES	C/C(=CC=C[C@@]1(C)OC(=O)[C@]23[C@]([C@@H]1CC2)(O)CCC(=CC3)C(=O)[O-])/C(=O)[O-]
Standard InCHI	InChI=1S/C20H24O7/c1-12(15(21)22)4-3-8-18(2)14-7-10-19(17(25)27-18)9-5-13(16(23)24)6-11-20(14,19)26/h3-5,8,14,26H,6-7,9-11H2,1-2H3,(H,21,22)(H,23,24)/p-2/b8-3+,12-4+/t14-,18-,19-,20+/m1/s1
Standard InCHIKey	QPFFEVMIQIJTGZ-ZISPUWBRSA-L
External Identifiers	ChEMBL [N/A]; PubChem [13992640];
Reference of Component-Ingredient Pair	12141871

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2141	Pseudolarix amabilis	Tu Jing Pi	åœŸè†çš®

Ingredient ID: TCMC5296
Formula: C29H38O13

Common Name	Pseudolaric Acid B-O-Î’-D-Glucopyranoside
IUPAC Name	methyl (1R,7S,8S,9R)-7-acetyloxy-9-methyl-9-[(1E,3E)-4-methyl-5-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypenta-1,3-dienyl]-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylate
Canonical SMILES	OC[C@H]1O[C@@H](OC(=O)/C(=C/C=C/[C@@]2(C)OC(=O)[C@]34[C@@]([C@H]2CC3)(CCC(=CC4)C(=O)OC)OC(=O)C)/C)[C@@H]([C@H]([C@@H]1O)O)O
Standard InCHI	InChI=1S/C29H38O13/c1-15(23(35)40-25-22(34)21(33)20(32)18(14-30)39-25)6-5-10-27(3)19-9-12-28(26(37)42-27)11-7-17(24(36)38-4)8-13-29(19,28)41-16(2)31/h5-7,10,18-22,25,30,32-34H,8-9,11-14H2,1-4H3/b10-5+,15-6+/t18-,19+,20-,21+,22-,25+,27-,28-,29+/m1/s1
Standard InCHIKey	UUDZDKPKXAEKLA-YHLOYHKPSA-N
External Identifiers	ChEMBL [CHEMBL447760]; PubChem [10031398];
Reference of Component-Ingredient Pair	22424731

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2141	Pseudolarix amabilis	Tu Jing Pi	åœŸè†çš®

Ingredient ID: TCMC5145
Formula: C22H26O8

Common Name	Pseudolaric Acid C2
IUPAC Name	(1R,7S,8S,9R)-7-acetyloxy-9-[(1E,3E)-4-carboxypenta-1,3-dienyl]-9-methyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylic acid
Canonical SMILES	CC(=O)O[C@@]12CCC(=CC[C@@]32CC[C@H]1[C@@](C)(/C=C/C=C(/C(=O)[O-])C)OC3=O)C(=O)[O-]
Standard InCHI	InChI=1S/C22H26O8/c1-13(17(24)25)5-4-9-20(3)16-8-11-21(19(28)30-20)10-6-15(18(26)27)7-12-22(16,21)29-14(2)23/h4-6,9,16H,7-8,10-12H2,1-3H3,(H,24,25)(H,26,27)/p-2/b9-4+,13-5+/t16-,20+,21+,22-/m0/s1
Standard InCHIKey	ZPSQWDVEMDWXPJ-HPHAYBORSA-L
External Identifiers	ChEMBL [CHEMBL373982]; PubChem [6475945];
Reference of Component-Ingredient Pair	22260030

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2141	Pseudolarix amabilis	Tu Jing Pi	åœŸè†çš®

Ingredient ID: TCMC5113
Formula: C21H26O7

Common Name	Pseudolaric Acid C
IUPAC Name	(2E,4E)-5-[(1R,7S,8R,9R)-7-hydroxy-4-methoxycarbonyl-9-methyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-en-9-yl]-2-methylpenta-2,4-dienoic acid
Canonical SMILES	COC(=O)C1=CC[C@@]23[C@@](CC1)(O)[C@@H](CC2)[C@@](OC3=O)(C)/C=C/C=C(/C(=O)[O-])C
Standard InCHI	InChI=1S/C21H26O7/c1-13(16(22)23)5-4-9-19(2)15-8-11-20(18(25)28-19)10-6-14(17(24)27-3)7-12-21(15,20)26/h4-6,9,15,26H,7-8,10-12H2,1-3H3,(H,22,23)/p-1/b9-4+,13-5+/t15-,19+,20+,21-/m0/s1
Standard InCHIKey	RBXVTEUAOTYIME-GPGKBOPFSA-M
External Identifiers	ChEMBL [CHEMBL225131]; PubChem [6440704];
Reference of Component-Ingredient Pair	22424731

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2141	Pseudolarix amabilis	Tu Jing Pi	åœŸè†çš®

Ingredient ID: TCMC2821
Formula: C23H28O8

Common Name	Pseudolaric Acid B
IUPAC Name	n.a.
Canonical SMILES	COC(=O)C1=CC[C@@]23[C@@](CC1)(OC(=O)C)[C@@H](CC2)[C@@](OC3=O)(C)/C=C/C=C(/C(=O)O)C
Standard InCHI	InChI=1S/C23H28O8/c1-14(18(25)26)6-5-10-21(3)17-9-12-22(20(28)31-21)11-7-16(19(27)29-4)8-13-23(17,22)30-15(2)24/h5-7,10,17H,8-9,11-13H2,1-4H3,(H,25,26)/b10-5+,14-6+/t17-,21+,22+,23-/m0/s1
Standard InCHIKey	VDGOFNMYZYBUDT-YDRCMHEVSA-N
External Identifiers	ChEMBL [CHEMBL218534]; PubChem [6475943];
Reference of Component-Ingredient Pair	29214772

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2090	Gastrodia elata	Tian Ma	å¤©éº»
TCMH2141	Pseudolarix amabilis	Tu Jing Pi	åœŸè†çš®

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC2821	C23H28O8	Pseudolaric Acid B	432.18	1.4043	3.11	1.587	8	1	116.2	12	3	31	0
TCMC5113	C21H26O7	Pseudolaric Acid C	389.1600281	0.3474	3	0.366	7	1	112.96	5	3	28	0
TCMC5145	C22H26O8	Pseudolaric Acid C2	416.1471177	-0.2023	3	0.304	8	0	132.86	6	3	30	0
TCMC5296	C29H38O13	Pseudolaric Acid B-O-Î’-D-Glucopyranoside	594.2312413	-0.5001	3.22	0.281	13	4	195.35	10	4	42	1
TCMC6068	C20H24O7	Deacetylpseudolaric Acid C2	374.136553	-0.5814	2.89	-0.436	7	1	126.79	4	3	27	0
TCMC6069	C20H26O5	Deacetylpseudolaric Acid A	345.1701989	0.9782	3.11	1.289	5	1	86.66	3	3	25	0
TCMC6420	C31H48O6	Pseudolarolide C	516.3450893	1.6659	4.21	7.282	6	1	82.06	5	6	37	1
TCMC6707	C28H38O11	Pseudolaric Acid A-O-Î’-D-Glucopyranoside	550.241412	0.1307	3.33	1.204	11	4	169.05	8	4	39	1
TCMC6981	C20H30O3	Pseudolaric Acid D	317.2116698	-0.5002	3.33	4.757	3	1	60.36	2	4	23	0
TCMC7023	C22H28O6	Pseudolaric Acid A	387.1807636	1.3573	3.22	2.029	6	0	92.73	5	3	28	0

Download Data

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Pseudolarix amabilis åœŸè†çš®

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC7023

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC6981

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC6707

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC6420

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC6069

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC6068

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC5296

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC5145

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC5113

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2821

Occurrence of the ingredient across TCM components

Properties

Download Data

Component: Pseudolarix amabilis åœŸè†çš®