TCM-ID Component

Component: Fel serpentis liquidum è›‡èƒ†æ±

Description of the Component

Component ID	TCMH1869
Latin Name	Fel serpentis liquidum
English Name	Snake bile
Chinese Pinyin Name	She Dan Zhi
中文名	è›‡èƒ†æ±
TCM Properties	Cold,Sweet,Bitter
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	Toxic
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx2129	Compound Powder of Snake-bile and Fritillary Bulb	å¤æ–¹è›‡èƒ†å·è´æ•£
TCMFx6919	Niu Huang She Dan Chuan Bei Capsules	ç‰›é»„è›‡èƒ†å·è´èƒ¶å›Š
TCMFx7225	Niu Huang She Dan Chuan Bei Di Pills	ç‰›é»„è›‡èƒ†å·è´æ»´ä¸¸
TCMFx344	Niu HuangÂ SheÂ Dan Chuan Bei Liquid	ç‰›é»„è›‡èƒ†å·è´æ¶²
TCMFx7113	She Dan Chen Pi Oral Liquid	è›‡èƒ†é™ˆçš®å£æœæ¶²
TCMF7107	She Zhu Ming Mu Eye Drops	éºç æ˜Žç›®æ»´çœ¼æ¶²
TCMFx1006	SheÂ Dan Chen Pi Capsule	è›‡èƒ†é™ˆçš®èƒ¶å›Š
TCMFx1005	SheÂ Dan Chen Pi Tablet	è›‡èƒ†é™ˆçš®ç‰‡
TCMFx1004	SheÂ Dan Chuan Bei Capsule	è›‡èƒ†å·è´èƒ¶å›Š
TCMFx1003	SheÂ Dan Chuan Bei Ruan Capsule	è›‡èƒ†å·è´è½¯èƒ¶å›Š
TCMFx1212	Shedan Chenpi Powder	è›‡èƒ†é™ˆçš®æ•£
TCMFx1508	Shedan Chenpi Powder	è›‡èƒ†é™ˆçš®æ•£
TCMFx1208	Shedan Chuanbei Powder	è›‡èƒ†å·è´æ•£
TCMFx1497	Shedan Chuanbei Powder	è›‡èƒ†å·è´æ•£
TCMFx422	WuÂ SheÂ Zhi Yang Pills	ä¹Œè›‡æ¢ç—’ä¸¸

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT175	GPBAR1	G-protein coupled bile acid receptor 1	GPCR	Q8TDU6

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC808
Formula: C27H46O4

Common Name	Bile Acid
IUPAC Name	(2S,4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid
Canonical SMILES	CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@@H]([C@@]3(C)CC[C@@H]2[C@@]2([C@H]1C[C@H](O)CC2)C)[C@@H](C[C@@H](C(=O)O)C)C
Standard InCHI	InChI=1S/C27H46O4/c1-6-18-22-14-17(28)9-11-27(22,5)21-10-12-26(4)19(15(2)13-16(3)25(30)31)7-8-20(26)23(21)24(18)29/h15-24,28-29H,6-14H2,1-5H3,(H,30,31)/t15-,16+,17-,18-,19-,20+,21+,22+,23+,24-,26-,27-/m1/s1
Standard InCHIKey	HSINOMROUCMIEA-FGVHQWLLSA-N
External Identifiers	ChEMBL [CHEMBL1258080]; PubChem [17755104];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1869	Fel serpentis liquidum	She Dan Zhi	è›‡èƒ†æ±

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC808	C27H46O4	Bile Acid	434.34	-0.3531	3.99	7.337	4	3	77.76	13	4	31	1

Download Data

All data can be downloaded by:

→ Selecting data type in the below download table
→ Then click the download button.

Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)