TCM-ID Component

Component: Drosera peltata var. lunata 茅膏菜

Description of the Component

Component ID	TCMH1454
Latin Name	Drosera peltata var. lunata
English Name	Lunate peltate sundew
Chinese Pinyin Name	Mao Gao Cai
中文名	茅膏菜
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx884	Qu Shang Xiao Zhong Tincture	祛伤消肿酊

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT191	STAT3	Signal transducer and activator of transcription 3	Transcription factor	P40763
TCMT195	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1	Kinase	Q02750
TCMT2	MAPT	Microtubule-associated protein tau	Unclassified	P10636
TCMT3	ALOX15	Arachidonate 15-lipoxygenase	Oxidoreductase	P16050
TCMT33	CYP3A4	Cytochrome P450 3A4	Oxidoreductase	P08684
TCMT336	IDO1	Indoleamine 2,3-dioxygenase	Oxidoreductase	P14902
TCMT565	EP300	Histone acetyltransferase p300	Transferase	Q09472
TCMT680	KAT2B	Histone acetyltransferase PCAF	Transferase	Q92831
TCMT704	ERBB2	Receptor protein-tyrosine kinase erbB-2	Kinase	P04626
TCMT8	KDM4E	Lysine-specific demethylase 4D-like	Oxidoreductase	B2RXH2
TCMT80	MAPK1	MAP kinase ERK2	Kinase	P28482

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1214	Enterococcus faecium
TCMT1218	Staphylococcus aureus
TCMT1229	Enterococcus faecalis
TCMT1251	Candida albicans
TCMT1438	Plasmodium falciparum
TCMT1439	Mycobacterium smegmatis
TCMT1455	Mycobacterium tuberculosis H37Rv
TCMT1458	Filobasidiella neoformans
TCMT1463	Mycobacterium tuberculosis

Ingredient Structrues

Ingredient ID: TCMC1916
Formula: C11H8O3

Common Name	Plumbagin
IUPAC Name	5-hydroxy-2-methylnaphthalene-1,4-dione
Canonical SMILES	CC1=CC(=O)c2c(C1=O)cccc2O
Standard InCHI	InChI=1S/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3
Standard InCHIKey	VCMMXZQDRFWYSE-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL295316]; PubChem [10205];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1493	Euphorbia pekinensis	Mian Da Ji	绵大戟
TCMH1454	Drosera peltata var. lunata	Mao Gao Cai	茅膏菜

Ingredient ID: TCMC1729
Formula: C10H8O2

Common Name	Naphthalene-1,4-Diol
IUPAC Name	naphthalene-1,4-diol
Canonical SMILES	Oc1ccc(c2c1cccc2)O
Standard InCHI	InChI=1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H
Standard InCHIKey	PCILLCXFKWDRMK-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL206816]; PubChem [11305];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1454	Drosera peltata var. lunata	Mao Gao Cai	茅膏菜

Ingredient ID: TCMC160
Formula: C20H26N2O2

Common Name	(R)-[(2S,4R,5S)-5-Ethyl-1-Azabicyclo[2.2.2]Octan-2-Yl]-(6-Methoxyquinolin-4-Yl)Methanol
IUPAC Name	(R)-[(2S,4R,5S)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
Canonical SMILES	CC[C@@H]1CN2CC[C@@H]1C[C@H]2[C@@H](c1ccnc2c1cc(OC)cc2)O
Standard InCHI	InChI=1S/C20H26N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3/t13-,14-,19+,20-/m1/s1
Standard InCHIKey	LJOQGZACKSYWCH-VPCNSNALSA-N
External Identifiers	ChEMBL [CHEMBL1436416]; PubChem [6916040];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1454	Drosera peltata var. lunata	Mao Gao Cai	茅膏菜

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC160	C20H26N2O2	(R)-[(2S,4R,5S)-5-Ethyl-1-Azabicyclo[2.2.2]Octan-2-Yl]-(6-Methoxyquinolin-4-Yl)Methanol	326.2	-1.4578	3.22	3.032	3	1	45.59	7	2	24	0
TCMC1729	C10H8O2	Naphthalene-1,4-Diol	160.05	-0.9206	2.34	2.324	0	2	40.46	2	2	12	0
TCMC1916	C11H8O3	Plumbagin	188.05	-0.1804	2.34	0.756	2	1	54.37	2	2	14	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)