Drug Information

Drug ID:  NPD262
Drug Name:  Chlorphentermine Hydrochloride
Molecular Formula:  C10H14ClN.ClH
Canonical SMILES:  CC(Cc1ccc(cc1)Cl)(N)C.Cl
Standard InCHI:  InChI=1S/C10H14ClN.ClH/c1-10(2,12)7-8-3-5-9(11)6-4-8;/h3-6H,7,12H2,1-2H3;1H
Standard InCHIKey:  WEJDYJKJPUPMLH-UHFFFAOYSA-N
Max Developmental Stage:  Approved
Max Developmental Stage Source:  ChEMBL

  Structural Similarity Between NPASS Natural Products and NPD262

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.


  Similar Natural Products

High Similarity Level: Tc>=0.85; Intermediate Similarity Level: 0.7 <= Tc < 0.85; Remote Similarity Level: 0.65 <= Tc < 0.7

Similarity Level Similarity Score Natural Product ID
Intermediate Similarity 0.7901 NPC122327
Intermediate Similarity 0.7901 NPC112609
Intermediate Similarity 0.7901 NPC113000
Intermediate Similarity 0.7831 NPC290638
Intermediate Similarity 0.7805 NPC276699
Intermediate Similarity 0.775 NPC229235
Intermediate Similarity 0.7619 NPC98269
Intermediate Similarity 0.7619 NPC325662
Intermediate Similarity 0.75 NPC139658
Intermediate Similarity 0.7111 NPC119677
Intermediate Similarity 0.7108 NPC219246
Intermediate Similarity 0.7048 NPC313981
Intermediate Similarity 0.703 NPC471310
Intermediate Similarity 0.7019 NPC77294
Intermediate Similarity 0.7013 NPC300345
Intermediate Similarity 0.7013 NPC212114
Intermediate Similarity 0.7013 NPC120441
Intermediate Similarity 0.7013 NPC65873
Remote Similarity 0.6962 NPC210849
Remote Similarity 0.6962 NPC54368
Remote Similarity 0.6962 NPC150196
Remote Similarity 0.6962 NPC135924
Remote Similarity 0.6962 NPC248705
Remote Similarity 0.6962 NPC200624
Remote Similarity 0.6941 NPC244738
Remote Similarity 0.6932 NPC12857
Remote Similarity 0.6915 NPC30445
Remote Similarity 0.6883 NPC198841
Remote Similarity 0.6883 NPC269586
Remote Similarity 0.6875 NPC29680
Remote Similarity 0.6847 NPC320656
Remote Similarity 0.6835 NPC147062
Remote Similarity 0.679 NPC88566
Remote Similarity 0.679 NPC50266
Remote Similarity 0.6789 NPC113099
Remote Similarity 0.6782 NPC98976
Remote Similarity 0.6753 NPC277704
Remote Similarity 0.6753 NPC149436
Remote Similarity 0.675 NPC246588
Remote Similarity 0.675 NPC310758
Remote Similarity 0.675 NPC238023
Remote Similarity 0.6737 NPC111233
Remote Similarity 0.6709 NPC8235
Remote Similarity 0.6709 NPC64270
Remote Similarity 0.6707 NPC32312
Remote Similarity 0.6707 NPC155172
Remote Similarity 0.6707 NPC198023
Remote Similarity 0.6705 NPC271642
Remote Similarity 0.6703 NPC231986
Remote Similarity 0.6667 NPC176858
Remote Similarity 0.6667 NPC169016
Remote Similarity 0.6627 NPC178527
Remote Similarity 0.6625 NPC169110
Remote Similarity 0.6598 NPC191444
Remote Similarity 0.6588 NPC200936
Remote Similarity 0.6585 NPC113670
Remote Similarity 0.6585 NPC45756
Remote Similarity 0.6571 NPC474559
Remote Similarity 0.6562 NPC12429
Remote Similarity 0.6548 NPC6107
Remote Similarity 0.6548 NPC267443
Remote Similarity 0.6526 NPC258046
Remote Similarity 0.6517 NPC110264
Remote Similarity 0.65 NPC36357
Remote Similarity 0.65 NPC18259
Remote Similarity 0.65 NPC114327
Remote Similarity 0.65 NPC119076
Remote Similarity 0.6489 NPC133162
Remote Similarity 0.6477 NPC299134
Remote Similarity 0.6463 NPC66517
Remote Similarity 0.6463 NPC22786
Remote Similarity 0.6463 NPC71009
Remote Similarity 0.6458 NPC262295
Remote Similarity 0.6458 NPC60408
Remote Similarity 0.6429 NPC113837
Remote Similarity 0.6429 NPC289915
Remote Similarity 0.64 NPC291070
Remote Similarity 0.64 NPC246757
Remote Similarity 0.6395 NPC246822
Remote Similarity 0.6395 NPC213570
Remote Similarity 0.6395 NPC139416
Remote Similarity 0.6386 NPC21211
Remote Similarity 0.6383 NPC104070
Remote Similarity 0.6383 NPC474088
Remote Similarity 0.6341 NPC134584
Remote Similarity 0.6339 NPC471318
Remote Similarity 0.6337 NPC329430
Remote Similarity 0.6327 NPC173991
Remote Similarity 0.6327 NPC240134
Remote Similarity 0.631 NPC291066
Remote Similarity 0.63 NPC108800
Remote Similarity 0.6265 NPC200745
Remote Similarity 0.625 NPC39799
Remote Similarity 0.625 NPC87099
Remote Similarity 0.625 NPC193578
Remote Similarity 0.625 NPC280135
Remote Similarity 0.625 NPC158028
Remote Similarity 0.625 NPC135433
Remote Similarity 0.625 NPC226999
Remote Similarity 0.625 NPC1008
Remote Similarity 0.6238 NPC469330
Remote Similarity 0.6237 NPC192623
Remote Similarity 0.6207 NPC473206
Remote Similarity 0.62 NPC470926
Remote Similarity 0.618 NPC54269
Remote Similarity 0.618 NPC212463
Remote Similarity 0.6163 NPC52330
Remote Similarity 0.6154 NPC290515
Remote Similarity 0.6154 NPC303611
Remote Similarity 0.6154 NPC108606
Remote Similarity 0.6154 NPC164514
Remote Similarity 0.6154 NPC226096
Remote Similarity 0.6145 NPC45255
Remote Similarity 0.6136 NPC263385
Remote Similarity 0.6136 NPC72670
Remote Similarity 0.6136 NPC251490
Remote Similarity 0.6122 NPC473031
Remote Similarity 0.6118 NPC264470
Remote Similarity 0.61 NPC316108
Remote Similarity 0.6092 NPC22760
Remote Similarity 0.6092 NPC311343
Remote Similarity 0.6078 NPC7067
Remote Similarity 0.6067 NPC74458
Remote Similarity 0.6064 NPC309279
Remote Similarity 0.6058 NPC10781
Remote Similarity 0.6058 NPC122493
Remote Similarity 0.6058 NPC293628
Remote Similarity 0.6047 NPC36440
Remote Similarity 0.6044 NPC189371
Remote Similarity 0.6044 NPC307195
Remote Similarity 0.6024 NPC147578
Remote Similarity 0.6023 NPC297358
Remote Similarity 0.6023 NPC98880
Remote Similarity 0.602 NPC203076
Remote Similarity 0.6019 NPC20142
Remote Similarity 0.6019 NPC215351
Remote Similarity 0.6 NPC470877
Remote Similarity 0.6 NPC1901
Remote Similarity 0.6 NPC285679
Remote Similarity 0.5962 NPC471320
Remote Similarity 0.5962 NPC471319
Remote Similarity 0.596 NPC471638
Remote Similarity 0.5955 NPC95289
Remote Similarity 0.5955 NPC271732
Remote Similarity 0.5941 NPC78041
Remote Similarity 0.5941 NPC78154
Remote Similarity 0.5941 NPC141139
Remote Similarity 0.5941 NPC209764
Remote Similarity 0.5941 NPC159178
Remote Similarity 0.5941 NPC121872
Remote Similarity 0.5941 NPC74936
Remote Similarity 0.5941 NPC471307
Remote Similarity 0.5938 NPC14326
Remote Similarity 0.5934 NPC96835
Remote Similarity 0.5934 NPC258492
Remote Similarity 0.5922 NPC322040
Remote Similarity 0.5914 NPC3190
Remote Similarity 0.5914 NPC298023
Remote Similarity 0.5914 NPC249018
Remote Similarity 0.5909 NPC82770
Remote Similarity 0.5909 NPC239931
Remote Similarity 0.5909 NPC78954
Remote Similarity 0.5905 NPC324569
Remote Similarity 0.5897 NPC476440
Remote Similarity 0.5895 NPC475573
Remote Similarity 0.5895 NPC475289
Remote Similarity 0.5889 NPC125144
Remote Similarity 0.5889 NPC208302
Remote Similarity 0.5889 NPC121708
Remote Similarity 0.5889 NPC326200
Remote Similarity 0.5882 NPC245259
Remote Similarity 0.5882 NPC226438
Remote Similarity 0.5882 NPC317564
Remote Similarity 0.5876 NPC149263
Remote Similarity 0.5872 NPC275467
Remote Similarity 0.5872 NPC304761
Remote Similarity 0.5872 NPC150254
Remote Similarity 0.5872 NPC226778
Remote Similarity 0.5872 NPC147000
Remote Similarity 0.587 NPC301874
Remote Similarity 0.5865 NPC303045
Remote Similarity 0.5865 NPC161972
Remote Similarity 0.5851 NPC224544
Remote Similarity 0.5851 NPC103488
Remote Similarity 0.5843 NPC5324
Remote Similarity 0.5843 NPC16190
Remote Similarity 0.5843 NPC169222
Remote Similarity 0.5843 NPC235059
Remote Similarity 0.5833 NPC327226
Remote Similarity 0.5825 NPC473661
Remote Similarity 0.5824 NPC271437
Remote Similarity 0.5818 NPC67043
Remote Similarity 0.581 NPC25565
Remote Similarity 0.5806 NPC302129
Remote Similarity 0.5794 NPC125732
Remote Similarity 0.5789 NPC159661
Remote Similarity 0.5769 NPC71140
Remote Similarity 0.5769 NPC471309
Remote Similarity 0.5766 NPC327481
Remote Similarity 0.5766 NPC473498

Drug Structure

External Identifiers

TTD  
DrugBank  
ChEMBL  
IUPHAR/BPS  
PharmaGKB  
KEGG Drug  
PubChem CID  
ChEBI  
CAS Number  

Drug Properties

Molecular Weight  183.08
ALogP  0.9097
MLogP  2.34
XLogP  3.04
HDA  1
HBD  1
Rotatable Bonds  6
TPSA  26.02
RO5 Violation  0