NPASS Compound

Natural Product: NPC314408

Natural Product ID	NPC314408
Common Name ? The InCHIKey will be temporarily assigned as the "Common Name" if no IUPAC name or alternative short name is available.	Tobramycin
IUPAC Name	(2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
Synonyms	47663; Aktob; Bethkis; Bramitob; Nebcin; Nebicin; Nebramycin; Nebramycin Factor 6; Nebris; Obramycin; Tobi; Tobradex; Tobradex St; Tobralex; Tobramycin; Tobravisc; Tobrex; Tymbrineb; Vantobra
Synthetic Gene Cluster	n.a.
ChEMBL Identifier	CHEMBL1747
PubChem CID	36294
Chemical Classification	CHEMONTID:0000000 [Organic compounds] [CHEMONTID:0004603] Organic oxygen compounds [CHEMONTID:0000323] Organooxygen compounds [CHEMONTID:0000011] Carbohydrates and carbohydrate conjugates [CHEMONTID:0003305] Aminosaccharides [CHEMONTID:0000282] Aminoglycosides [CHEMONTID:0001675] Aminocyclitol glycosides [CHEMONTID:0003575] 2-deoxystreptamine aminoglycosides [CHEMONTID:0003574] 4,6-disubstituted 2-deoxystreptamines

The Chemical Classification was calculated by Classyfire, a software for chemical taxonomy calculation. Reference: DOI:10.1186/s13321-016-0174-y.

Chemical Representations

RDKit 3D 69 71 0 0 0 0 0 0 0 0999 V2000 -0.1224 0.7934 -2.4893 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5873 -0.5241 -1.9168 C 0 0 1 0 0 0 0 0 0 0 0 0 -1.1238 -0.2060 -0.5348 C 0 0 2 0 0 0 0 0 0 0 0 0 -0.0079 0.1634 0.4007 C 0 0 1 0 0 0 0 0 0 0 0 0 1.1428 0.8482 -0.2907 C 0 0 2 0 0 0 0 0 0 0 0 0 0.7478 1.5429 -1.5650 C 0 0 2 0 0 0 0 0 0 0 0 0 0.1628 2.8492 -1.2969 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1011 -0.0766 -0.5764 O 0 0 0 0 0 0 0 0 0 0 0 0 3.3208 0.0940 0.0067 C 0 0 2 0 0 0 0 0 0 0 0 0 4.4570 0.3277 -0.9503 C 0 0 1 0 0 0 0 0 0 0 0 0 5.5464 1.0350 -0.1295 C 0 0 2 0 0 0 0 0 0 0 0 0 5.6094 0.4406 1.2477 C 0 0 1 0 0 0 0 0 0 0 0 0 4.9131 -0.8849 1.3665 C 0 0 1 0 0 0 0 0 0 0 0 0 5.0142 -1.2980 2.8196 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5829 -2.5965 3.0405 O 0 0 0 0 0 0 0 0 0 0 0 0 3.6556 -0.9292 0.8566 O 0 0 0 0 0 0 0 0 0 0 0 0 6.9534 0.2361 1.5595 O 0 0 0 0 0 0 0 0 0 0 0 0 5.1611 2.4326 0.0230 N 0 0 0 0 0 0 0 0 0 0 0 0 5.0473 -0.8752 -1.3622 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.5365 0.9229 1.4457 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.9336 -1.2068 -0.0670 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.2464 -0.8450 0.1090 C 0 0 2 0 0 0 0 0 0 0 0 0 -3.6983 -0.8839 1.5670 C 0 0 1 0 0 0 0 0 0 0 0 0 -4.9137 0.0541 1.6134 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9230 -0.5006 0.6576 C 0 0 1 0 0 0 0 0 0 0 0 0 -5.3890 -0.9487 -0.6506 C 0 0 1 0 0 0 0 0 0 0 0 0 -5.4191 0.1855 -1.6821 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.1313 -0.4352 -2.9602 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.1608 -1.5710 -0.6117 O 0 0 0 0 0 0 0 0 0 0 0 0 -6.6820 -1.4891 1.3046 O 0 0 0 0 0 0 0 0 0 0 0 0 -4.2096 -2.2080 1.8183 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.7364 -0.9421 -2.7261 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.0624 1.3810 -2.6751 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3438 0.6678 -3.4924 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2009 -1.2979 -1.9058 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7663 0.7070 -0.6635 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3655 -0.7769 0.8577 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4682 1.6540 0.4014 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7149 1.7777 -2.1035 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2047 3.2463 -2.1824 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9217 3.4648 -0.9566 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2544 1.0294 0.6396 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2288 1.0030 -1.7742 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4866 0.9793 -0.6925 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1981 1.1047 2.0385 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5459 -1.6274 0.7995 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0930 -1.2495 3.0899 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5006 -0.5644 3.4879 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1807 -3.0488 3.6854 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5492 0.3581 0.7784 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9372 3.0247 0.3422 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6432 2.7724 -0.7954 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8047 -1.1314 -2.2697 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3660 1.8792 1.2046 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3137 0.2415 -0.1938 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9135 -0.5766 2.2556 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.3140 -0.0162 2.6404 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.6041 1.0904 1.3767 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.6602 0.3314 0.4564 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.1135 -1.7134 -1.0646 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.7453 1.0007 -1.4271 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.4969 0.5131 -1.7327 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3102 0.0379 -3.4291 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.9152 -0.3532 -3.6428 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.6648 -1.2868 2.2938 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9324 -2.9234 1.1395 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.2519 -2.4827 2.8028 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8924 -1.9743 -2.6465 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5042 -0.7461 -3.7231 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 2 3 1 0 3 4 1 0 4 5 1 0 5 6 1 0 6 7 1 0 5 8 1 0 8 9 1 0 9 10 1 0 10 11 1 0 11 12 1 0 12 13 1 0 13 14 1 0 14 15 1 0 13 16 1 0 12 17 1 0 11 18 1 0 10 19 1 0 4 20 1 0 3 21 1 0 21 22 1 0 22 23 1 0 23 24 1 0 24 25 1 0 25 26 1 0 26 27 1 0 27 28 1 0 26 29 1 0 25 30 1 0 23 31 1 0 2 32 1 0 6 1 1 0 16 9 1 0 29 22 1 0 1 33 1 0 1 34 1 0 2 35 1 1 3 36 1 6 4 37 1 1 5 38 1 1 6 39 1 6 7 40 1 0 7 41 1 0 9 42 1 1 10 43 1 6 11 44 1 6 12 45 1 1 13 46 1 6 14 47 1 0 14 48 1 0 15 49 1 0 17 50 1 0 18 51 1 0 18 52 1 0 19 53 1 0 20 54 1 0 22 55 1 6 23 56 1 1 24 57 1 0 24 58 1 0 25 59 1 6 26 60 1 6 27 61 1 0 27 62 1 0 28 63 1 0 28 64 1 0 30 65 1 0 31 66 1 0 31 67 1 0 32 68 1 0 32 69 1 0 M END

Standard InCHIKey	NLVFBUXFDBBNBW-PBSUHMDJSA-N
Standard InCHI	InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1
SMILES	C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)N)O)O)O[C@@H]1[C@@H](C[C@@H]([C@@H](CN)O1)O)N)N

Calculated Properties

Physi-Chem Properties

Molecular Weight:	467.26	Volume:	428.311 ? Van der Waals volume.
Dense:	1.091	LogP:	-2.082 ? The logarithm of the n-octanol/water distribution coefficients.
logD7.4:	-1.529 ? The logarithm of the n-octanol/water distribution coefficient at pH=7.4.	LogS:	-0.318 ? The logarithm of aqueous solubility value.
Rotatable Bonds:	6.0	Rigid Bonds:	18.0
TPSA:	268.17 ? Topological Polar Surface Area.	H-Bond Acceptor:	14.0
H-Bond Donor:	15.0	Rings:	3.0
Heavy Atoms:	14.0

MedChem Properties

QED Drug-Likeness Score:	0.174	GASA:	1.0 ? GASA represents the probability of being difficult to synthesize, ranging from 0 to 1.
Synthetic Accessibility Score:	5.144	Fsp³:	1.0
MCE-18:	66.444 ? MCE-18 stands for medicinal chemistry evolution.MCE-18≥45 is considered a suitable value.	Lipinski Rule-of-5:	Accepted
Pfizer Rule:	Rejected	GSK Rule:	Accepted
Golden Triangle Rule:	Rejected	BMS Rule:	1
Chelating Alert:	0	PAINS Alert:	0
Colloidal aggregators:	0.668	Fluc inhibitor:	0.003 ? The fluc inhibitor value is the probability of being fLuc inhibitors, within the range of 0 to 1.
Blue fluorescence:	0.097 ? The blue fluorescence value is the probability of being blue fluorescence, within the range of 0 to 1	Green fluorescence:	0.003 ? The green fluorescence value is the probability of being green fluorescence, within the range of 0 to 1
Reactive compounds:	0.115	Promiscuous compounds:	0.004

ADMET Properties (ADMETlab3.0)

ADMET: Absorption

Caco-2 Permeability:	-6.107	MDCK Permeability:	-5.591
Pgp-inhibitor:	0.0	Pgp-substrate:	0.987
PAMPA:	1.0 ? The experimental data for Peff was logarithmically transformed (logPeff). Molecules with log Peff values below 2.0 were classified as low-permeability (Category 0), while those with log Peff values exceeding 2.5 were classified as high-permeability (Category 1).	Human Intestinal Absorption (HIA):	1.0
20% Bioavailability (F20%):	0.998	30% Bioavailability (F30%):	1.0
50% Bioavailability (F50%):	1.0

ADMET: Distribution

Blood-Brain-Barrier Penetration (BBB):	0.0	MRP1:	0.117
Plasma Protein Binding (PPB):	17.126%	Volume Distribution (VD):	-0.162
Fu:	82.745% ? The fraction unbound in plasms.	OATP1B1 inhibitor:	0.965
OATP1B3 inhibitor:	0.999	BCRP inhibitor:	0.0
BSEP inhibitor:	0.0

ADMET: Metabolism

CYP1A2-inhibitor:	0.003	CYP1A2-substrate:	0.0
CYP2C19-inhibitor:	1.0	CYP2C19-substrate:	0.0
CYP2C9-inhibitor:	0.0	CYP2C9-substrate:	0.0
CYP2D6-inhibitor:	0.265	CYP2D6-substrate:	0.0
CYP3A4-inhibitor:	1.0	CYP3A4-substrate:	0.0
CYP2B6-substrate:	0.0	CYP2C8-inhibitor:	0.0
HLM stability:	0.0 ? Human liver microsomal (HLM) stability. Category 0: stable+ (HLM > 30 min); Category 1: unstable- (HLM ≤ 30 min). The output value is the probability of human liver microsomal instability, where a value closer to 1 indicates a higher likelihood of instability.

ADMET: Excretion

Clearance (CL):

1.008

Half-life (T1/2):

2.08

ADMET: Toxicity

hERG Blockers:	0.018	hERG Blockers (10um):	0.039
Human Hepatotoxicity (H-HT):	0.792	Drug-induced Liver Injury (DILI):	0.007
AMES Toxicity:	0.414	Rat Oral Acute Toxicity:	0.004
Maximum Recommended Daily Dose:	0.088	Skin Sensitization:	1.0
Carcinogencity:	0.022	Eye Corrosion:	0.0
Eye Irritation:	0.0	Respiratory Toxicity:	0.016
Drug-induced Neurotoxicity:	0.235	Ototoxicity:	1.0
Hematotoxicity:	0.182	Drug-induced Nephrotoxicity:	0.876
Genotoxicity:	0.02	RPMI-8226 Immunitoxicity:	0.276
A549 Cytotoxicity:	0.126	Hek293 Cytotoxicity:	0.008
BCF:	0.01 ? Bioconcentration factors are used for considering secondary poisoning potential and assessing risks to human health via the food chain. The unit is -log10[(mg/L)/(1000*MW)].	IGC50:	2.082 ? 48 hour Tetrahymena pyriformis IGC50. The unit of IGC50 is -log10[(mg/L)/(1000*MW)].
LC50DM:	3.287 ? 48 hour Daphnia magna LC50. The unit of LC50DM is -log10[(mg/L)/(1000*MW)].	LC50FM:	1.972 ? 96 hour fathead minnow LC50. The unit of LC50FM is -log10[(mg/L)/(1000*MW)].

Species Source

Organism ID	Organism Name	Taxonomy Level	Family	SuperKingdom	Isolation Part	Collection Location	Collection Time	Reference
NPO40937	Streptomycetes sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[27690254]
NPO41037	Serratia plymuthica MF371-2	Strain	Yersiniaceae	Bacteria	n.a.	n.a.	n.a.	PMID[29083894]
NPO40446	Aspergillus fumigatus HNMF0047	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	PMID[30070829]
NPO40446	Aspergillus fumigatus HNMF0047	Strain	Aspergillaceae	Eukaryota	n.a.	n.a.	n.a.	Database[COCONUT]

Note for Reference:
In addition to directly collecting NP source organism data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated them from below databases:
☉ UNPD: Universal Natural Products Database [PMID: 23638153].
☉ StreptomeDB: a database of streptomycetes natural products [PMID: 33051671].
☉ TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine [PMID: 26156871].
☉ TCM@Taiwan: a Traditional Chinese Medicine database [PMID: 21253603].
☉ TCMID: a Traditional Chinese Medicine database [PMID: 29106634].
☉ TCMSP: The traditional Chinese medicine systems pharmacology database and analysis platform [PMID: 24735618].
☉ HerDing: a herb recommendation system to treat diseases using genes and chemicals [PMID: 26980517].
☉ MetaboLights: a metabolomics database [PMID: 27010336].
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

NP Quantity Composition/Concentration

Organism ID	Organism Name	Organism Material Preparation	Organism Part	NP Quantity (Standard)	NP Quantity (Minimum)	NP Quantity (Maximum)	Quantity Unit	Reference

Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP quantitative records for specific NP domains (e.g., NPS from foods or herbs) from domain-specific databases. These databases include:
☉ DUKE: Dr. Duke's Phytochemical and Ethnobotanical Databases.
☉ PHENOL EXPLORER: is the first comprehensive database on polyphenol content in foods [PMID: 24103452], its homepage can be accessed at here.
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

Biological Activity

Activity Type	# Activity
MIC	1157
Kd	19
Frel	1
Inhibition	14
Tm	3
IC50	7
Potency	1
Activity	121
MIC50	88
MIC90	85
fc max/MIC	2
fAUC/MIC	2
TIME	39
BBC	5
EC50	4
IZ	7
FC	26
Ratio	3
FICI	15
log10cfu	7
Composite Activity - Active	1
Composite Activity - Marginal	1
HepSE_bilirubinemia	1
HepSE_cholecystitis	1
HepSE_cholelithiasis	1
HepSE_cirrhosis	1
HepSE_hepatic failure	1
HepSE_hepatic necrosis	1
HepSE_hepatomegaly	1
HepSE_jaundice	2
HepSE_liver fatty	1
HepSE_liver function tests abnormal	1
HepSE_Combined Scores	1
MBC	13
GI	2
Hepatotoxicity (acute)	1
MBIC	1
Ki	1
MBC99.9	2
Inhibition index	1
HC10	1
INH	4
MIC80	8
FIC	14
log(activity)	8
MBIC90	1
MBIC50	2
HepSE_liver disease	1
Hepatotoxicity (moderate)	2
Hepatotoxicity (granulomatous hepatitis)	1
Hepatotoxicity (benign tumour)	1
CC50	1
fc max	1
Mortality	2
fAUC	1
MTD	1
HepSE_elevated liver function tests	1
HepSE_hepatitis	1
ALT	10
ALB	10
ALP	10
AST	10
BUN	10
CHLORIDE	10
CHOL	10
CK	10
CREAT	10
GLUC	10
LDH	10
LIPASE	10
PHOS	10
POTASSIUM	10
SODIUM	10
BILI	10
PROT	10
URATE	10
BASO	6
EOS	6
LYM	6
MONO	6
NEUTSG	6
BASOLE	10
EOSLE	10
RBC	10
HCT	10
HGB	10
WBC	10
LYMLE	10
MCH	10
MCHC	10
MCV	10
MONOLE	10
NEUTLE	10
PLAT	10
CO2	4
Survival	3

Activity Type	# Activity
Individual protein	12
Cell line	5
Nucleic-acid	3
Single protein	2
Organism	1915
Unchecked	1
Nucleic acid	16
Others	3
Non-molecular	65
Phenotype	17

Molecular-level activity

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT1249	Individual protein	Canalicular multispecific organic anion transporter 2	Homo sapiens	IC50	>	133000.0	nM	PMID[23956101]
NPT1028	Individual protein	Multidrug resistance-associated protein 4	Homo sapiens	IC50	>	133000.0	nM	PMID[23956101]
NPT72	Individual protein	Solute carrier organic anion transporter family member 1B3	Homo sapiens	Inhibition	=	105.18	%	PMID[23571415]
NPT713	Individual protein	Bile salt export pump	Homo sapiens	IC50	>	133000.0	nM	PMID[23956101]
NPT28957	Nucleic-acid	i-motif DNA	n.a.	Kd	=	13000.0	nM	PMID[35835380]
NPT28957	Nucleic-acid	i-motif DNA	n.a.	Kd	=	17000.0	nM	PMID[35835380]
NPT317	Nucleic acid	Nucleic Acid	n.a.	MIC	=	10000.0	nM	PMID[9457241]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	2070.0	nM	PMID[11814798]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	2040.0	nM	PMID[11814798]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	2120.0	nM	PMID[11814798]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	680.0	nM	PMID[11814798]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	2110.0	nM	PMID[10915059]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	1680.0	nM	PMID[10915059]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	3260.0	nM	PMID[12127547]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	430.0	nM	PMID[12127547]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	2910.0	nM	PMID[12127547]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	5370.0	nM	PMID[12127547]
NPT4383	Nucleic acid	Ribosomal RNA A-site	n.a.	Kd	=	1500.0	nM	PMID[11206440]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Frel	=	0.33	n.a.	PMID[15808490]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	=	80.0	nM	PMID[19445516]
NPT317	Nucleic acid	Nucleic Acid	n.a.	Kd	>	100000.0	nM	PMID[22257890]
NPT73	Individual protein	Solute carrier organic anion transporter family member 1B1	Homo sapiens	Inhibition	=	197.1	%	PMID[23571415]
NPT612	Individual protein	Canalicular multispecific organic anion transporter 1	Homo sapiens	IC50	>	133000.0	nM	PMID[23956101]
NPT4383	Nucleic acid	Ribosomal RNA A-site	n.a.	IC50	=	70.0	nM	PMID[27509271]
NPT20556	Single protein	Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	13.99	%	DOI[10.6019/CHEMBL4495564]
NPT28098	Nucleic-acid	dsDNA	Homo sapiens	Kd	=	18000.0	nM	PMID[35835380]
NPT692	Individual protein	Histone deacetylase 6	Homo sapiens	Inhibition	=	-5.82	%	HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activators
NPT692	Individual protein	Histone deacetylase 6	Homo sapiens	Inhibition	=	-7.53	%	HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activators
NPT29454	Single protein	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	Homo sapiens	Inhibition	=	8.283	%	PMID[38318365]
NPT4977	Individual protein	Human immunodeficiency virus type 1 REV	Human immunodeficiency virus 1	Kd	=	4110.0	nM	PMID[11354359]
NPT4999	Individual protein	Menin	Homo sapiens	Tm	=	41.43	degrees C	PMID[24709560]
NPT4999	Individual protein	Menin	Homo sapiens	Tm	=	42.61	degrees C	PMID[24709560]
NPT4999	Individual protein	Menin	Homo sapiens	Tm	=	43.35	degrees C	PMID[24709560]

In vitro activity

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT189	Cell line	Vero	Chlorocebus aethiops	IC50	>	200.0	ug.mL-1	PMID[28291943]
NPT1886	Cell line	J774	Mus musculus	Activity	=	99.7	%	PMID[30282323]
NPT1886	Cell line	J774	Mus musculus	Activity	=	83.2	%	PMID[30282323]
NPT71	Cell line	HEK293	Homo sapiens	CC50	>	20000.0	nM	DOI[10.6019/CHEMBL4513161]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	0.25	ug.mL-1	PMID[17638702]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	0.5	ug.mL-1	PMID[17638702]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	1.0	ug.mL-1	PMID[17638702]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	16.0	ug.mL-1	PMID[24126094]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC	=	0.5	ug.mL-1	PMID[19015360]
NPT2895	Organism	Providencia stuartii	Providencia stuartii	MIC	=	2.0	ug.mL-1	PMID[3701779]
NPT2895	Organism	Providencia stuartii	Providencia stuartii	MIC	=	16.0	ug.mL-1	PMID[3701779]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	=	64.0	ug.mL-1	PMID[17261621]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	0.047	ug.mL-1	PMID[17638702]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	0.125	ug.mL-1	PMID[17638702]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	0.38	ug.mL-1	PMID[17638702]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	1.5	ug.mL-1	PMID[17638702]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	32.0	ug.mL-1	PMID[24126094]
NPT1264	Organism	Burkholderia cepacia	Burkholderia cepacia	MIC50	>	32.0	ug.mL-1	PMID[19805554]
NPT1264	Organism	Burkholderia cepacia	Burkholderia cepacia	MIC90	>	32.0	ug.mL-1	PMID[19805554]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	EC50	=	1.0	ug.mL-1	PMID[18172002]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	EC50	=	19.0	ug.mL-1	PMID[18172002]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC	=	4.0	ug.mL-1	PMID[18172002]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC	=	125.0	ug.mL-1	PMID[18172002]
NPT5768	Organism	Acinetobacter pittii	Acinetobacter pittii	MIC	>=	0.5	ug.mL-1	PMID[20368407]
NPT5768	Organism	Acinetobacter pittii	Acinetobacter pittii	MIC50	=	8.0	ug.mL-1	PMID[20368407]
NPT5768	Organism	Acinetobacter pittii	Acinetobacter pittii	MIC90	>=	16.0	ug.mL-1	PMID[20368407]
NPT5768	Organism	Acinetobacter pittii	Acinetobacter pittii	Activity	=	42.1	%	PMID[20368407]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	>	256.0	ug.mL-1	PMID[18838598]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	>	8.0	ug.mL-1	PMID[18490506]
NPT5311	Organism	Mycobacterium mageritense	Mycobacterium mageritense	MIC	=	8.0	ug.mL-1	PMID[18725441]
NPT5768	Organism	Acinetobacter pittii	Acinetobacter pittii	MIC	=	0.25	ug.mL-1	PMID[18505859]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC	=	4.0	ug.mL-1	PMID[19015360]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC50	=	8.0	ug.mL-1	PMID[19015360]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC90	>	32.0	ug.mL-1	PMID[19015360]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	2.0	ug.mL-1	PMID[19289526]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	>	16.0	ug.mL-1	PMID[24126094]
NPT1118	Organism	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC	=	4.0	ug.mL-1	PMID[19506065]
NPT1118	Organism	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC	=	1.0	ug.mL-1	PMID[19506065]
NPT1118	Organism	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC50	=	8.0	ug.mL-1	PMID[19506065]
NPT1118	Organism	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC90	=	16.0	ug.mL-1	PMID[19506065]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	<=	0.03	ug.mL-1	PMID[19506065]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC50	=	0.25	ug.mL-1	PMID[19506065]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC90	=	0.5	ug.mL-1	PMID[19506065]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	Activity	=	99.0	%	PMID[19506065]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	0.12	ug.mL-1	PMID[19506065]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	Activity	=	100.0	%	PMID[19721071]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC50	=	0.25	ug.mL-1	PMID[19506065]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC90	=	1.0	ug.mL-1	PMID[19506065]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC	=	1.0	ug.mL-1	PMID[19506065]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC50	=	2.0	ug.mL-1	PMID[19506065]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC50	=	4.0	ug.mL-1	PMID[19506065]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC90	=	8.0	ug.mL-1	PMID[19506065]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC	=	0.25	ug.mL-1	PMID[19506065]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC50	=	1.0	ug.mL-1	PMID[19506065]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC90	=	4.0	ug.mL-1	PMID[19506065]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	Activity	=	100.0	%	PMID[19506065]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	Activity	=	89.0	%	PMID[19721071]
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	Activity	=	0.0	%	PMID[19721071]
NPT2897	Organism	Citrobacter freundii	Citrobacter freundii	MIC	>	8.0	ug.mL-1	PMID[18490506]
NPT1207	Organism	Acinetobacter	Acinetobacter	MIC	>	8.0	ug.mL-1	PMID[18490506]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	=	8.0	ug.mL-1	PMID[18490506]
NPT1264	Organism	Burkholderia cepacia	Burkholderia cepacia	MIC	>	40.0	ug.mL-1	PMID[21905738]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	IZ	=	18.0	mm	DOI[10.1007/s00044-011-9911-y]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC	=	18.8	ug.mL-1	PMID[23786357]
NPT1550	Organism	Bacillus anthracis	Bacillus anthracis	MIC	=	9.4	ug.mL-1	PMID[23786357]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	>	32.0	ug.mL-1	PMID[24126094]
NPT1204	Organism	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC	>	128.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT1605	Organism	Enterococcus	Enterococcus	MIC	>	128.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC	=	4.7	ug.mL-1	PMID[26617967]
NPT1118	Organism	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC	=	2.0	ug.mL-1	PMID[28409644]
NPT20555	Organism	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	Inhibition index	=	0.06782	n.a.	DOI[10.1101/2020.04.03.023846]
NPT20555	Organism	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	2.66	%	DOI[10.21203/rs.3.rs-23951/v1]
NPT1122	Organism	Haemophilus influenzae	Haemophilus influenzae	MIC	=	4.0	ug.mL-1	PMID[27509271]
NPT1264	Organism	Burkholderia cepacia	Burkholderia cepacia	MIC	>	32.0	ug.mL-1	PMID[27509271]
NPT20555	Organism	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	-0.18	%	DOI[10.6019/CHEMBL4495565]
NPT1264	Organism	Burkholderia cepacia	Burkholderia cepacia	INH	>	64.0	ug ml-1	PMID[32033878]
NPT1190	Organism	Salmonella enterica	Salmonella enterica	INH	=	8.0	ug ml-1	PMID[32033878]
NPT1033	Organism	Enterobacter cloacae	Enterobacter cloacae	MIC	>	512.0	ug.mL-1	PMID[37122541]
NPT28438	Unchecked	Unchecked	n.a.	Inhibition	=	10.0	%	PMID[31931338]
NPT28747	Organism	Staphylococcus chromogenes	Staphylococcus chromogenes	MIC	=	2.0	ug.mL-1	PMID[35675753]
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	32.0	ug.mL-1	PMID[11425542]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	0.06	ug.mL-1	PMID[3701779]
NPT2894	Organism	Providencia rettgeri	Providencia rettgeri	MIC	=	0.13	ug.mL-1	PMID[3701779]
NPT2894	Organism	Providencia rettgeri	Providencia rettgeri	MIC	=	32.0	ug.mL-1	PMID[3701779]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	Kd	=	38000.0	nM	PMID[15808490]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	1.0	ug.mL-1	PMID[19349095]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	Activity	=	0.4	n.a.	PMID[17353241]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	Activity	=	1.51	n.a.	PMID[17353241]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	Activity	=	0.78	n.a.	PMID[17353241]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	Activity	=	1.36	n.a.	PMID[17353241]
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC50	=	16.0	ug.mL-1	PMID[18725441]
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC90	=	64.0	ug.mL-1	PMID[17353252]
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	128.0	ug.mL-1	PMID[17353252]
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	64.0	ug.mL-1	PMID[17353252]
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	Activity	=	41.8	%	PMID[17452479]
NPT5739	Organism	Enterobacteriaceae	Enterobacteriaceae	Activity	=	8.5	%	PMID[17452479]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	fc max/MIC	=	19.0	n.a.	PMID[17470655]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	1.0	ug.mL-1	PMID[19770278]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	fAUC/MIC	=	43.0	n.a.	PMID[17470655]
NPT2911	Organism	Pseudomonas putida	Pseudomonas putida	MIC	>	16.0	ug.mL-1	PMID[17470660]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	0.5	ug.mL-1	PMID[19258280]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	MIC	>=	256.0	ug.mL-1	PMID[17785513]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	16.0	ug.mL-1	PMID[19289526]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	MIC	=	0.25	ug.mL-1	PMID[17938184]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	64.0	ug.mL-1	PMID[17938181]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	0.75	ug.mL-1	PMID[17938181]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	4.0	ug.mL-1	PMID[24083676]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	2.14	mmol/ml	PMID[20207052]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	0.25	ug.mL-1	PMID[19015360]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	0.125	ug.mL-1	PMID[19858254]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	64.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC50	>	32.0	ug.mL-1	PMID[19805554]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC90	>	32.0	ug.mL-1	PMID[19805554]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	EC50	=	2.5	ug.mL-1	PMID[18172002]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	EC50	=	75.0	ug.mL-1	PMID[18172002]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	8.0	ug.mL-1	PMID[18725441]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	250.0	ug.mL-1	PMID[18172002]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>=	16.0	ug.mL-1	PMID[19289526]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	2.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT2905	Organism	Nocardia farcinica	Nocardia farcinica	MIC	>	1024.0	ug.mL-1	PMID[20308368]
NPT2905	Organism	Nocardia farcinica	Nocardia farcinica	MIC	=	64.0	ug.mL-1	PMID[20308368]
NPT2905	Organism	Nocardia farcinica	Nocardia farcinica	MIC	=	32.0	ug.mL-1	PMID[20308368]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	0.2	ug.mL-1	PMID[18694947]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Activity	=	56.0	%	PMID[20404121]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	256.0	ug.mL-1	PMID[18838598]
NPT2911	Organism	Pseudomonas putida	Pseudomonas putida	MIC	>	8.0	ug.mL-1	PMID[18852270]
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC90	=	32.0	ug.mL-1	PMID[18725441]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	1.0	ug.mL-1	PMID[18725441]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	4.0	ug.mL-1	PMID[18725441]
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	<=	0.03	ug.mL-1	PMID[18725441]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	0.5	ug.mL-1	PMID[18725441]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	Activity	=	20.0	mg.min/L	PMID[18195062]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	FC	=	1.5	n.a.	PMID[18195062]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	FC	=	0.9	n.a.	PMID[18195062]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	FC	=	0.2	n.a.	PMID[18195062]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	Activity	=	70.0	%	PMID[18195062]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	Activity	=	30.0	mg.min/L	PMID[18195062]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	Activity	=	1000.0	mg.min/L	PMID[18195062]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	Ratio	=	33.0	n.a.	PMID[18195062]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	64.0	ug.mL-1	PMID[18519712]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	0.5	ug.mL-1	PMID[19015360]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	8.0	ug.mL-1	PMID[18490506]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	32.0	ug.mL-1	PMID[19770287]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	>	32.0	ug.mL-1	PMID[19015360]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	16.0	ug.mL-1	PMID[19015360]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	32.0	ug.mL-1	PMID[19001116]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	FC	=	760.0	n.a.	PMID[19307375]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	FC	=	3300.0	n.a.	PMID[19307375]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	MIC	=	1.5	ug.mL-1	PMID[19307375]
NPT1466	Organism	Escherichia coli K12	Escherichia coli K-12	MIC	=	2.0	ug.mL-1	PMID[19307375]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	1.5	ug.mL-1	PMID[20696867]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	1.75	ug.mL-1	PMID[19332676]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	6.0	ug.mL-1	PMID[19332676]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	3.75	ug.mL-1	PMID[19332676]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	3.5	ug.mL-1	PMID[19332676]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	0.9	ug.mL-1	PMID[19332676]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	1.06	ug.mL-1	PMID[19332676]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	1.37	ug.mL-1	PMID[19332676]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	1.19	ug.mL-1	PMID[19332676]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	1.25	ug.mL-1	PMID[19332676]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	16.0	ug.mL-1	PMID[19289526]
NPT564	Organism	Listeria monocytogenes	Listeria monocytogenes	MIC90	=	0.12	ug.mL-1	PMID[19506065]
NPT564	Organism	Listeria monocytogenes	Listeria monocytogenes	MIC50	=	0.12	ug.mL-1	PMID[19506065]
NPT564	Organism	Listeria monocytogenes	Listeria monocytogenes	MIC	<=	0.06	ug.mL-1	PMID[19506065]
NPT4840	Organism	Staphylococcus lugdunensis	Staphylococcus lugdunensis	MIC	=	0.03	ug.mL-1	PMID[19506065]
NPT5312	Organism	Staphylococcus warneri	Staphylococcus warneri	MIC	=	0.015	ug.mL-1	PMID[19506065]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	0.25	ug.mL-1	PMID[19188376]
NPT4840	Organism	Staphylococcus lugdunensis	Staphylococcus lugdunensis	MIC50	=	0.12	ug.mL-1	PMID[19506065]
NPT5312	Organism	Staphylococcus warneri	Staphylococcus warneri	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT4840	Organism	Staphylococcus lugdunensis	Staphylococcus lugdunensis	MIC90	=	32.0	ug.mL-1	PMID[19506065]
NPT5312	Organism	Staphylococcus warneri	Staphylococcus warneri	MIC90	=	8.0	ug.mL-1	PMID[19506065]
NPT4840	Organism	Staphylococcus lugdunensis	Staphylococcus lugdunensis	Activity	=	46.7	%	PMID[19506065]
NPT5312	Organism	Staphylococcus warneri	Staphylococcus warneri	Activity	=	34.0	%	PMID[19506065]
NPT2710	Organism	Streptococcus agalactiae	Streptococcus agalactiae	MIC	=	0.015	ug.mL-1	PMID[19506065]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	=	0.008	ug.mL-1	PMID[19506065]
NPT2710	Organism	Streptococcus agalactiae	Streptococcus agalactiae	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT2710	Organism	Streptococcus agalactiae	Streptococcus agalactiae	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT2710	Organism	Streptococcus agalactiae	Streptococcus agalactiae	Activity	=	73.0	%	PMID[19506065]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Activity	=	74.0	%	PMID[19506065]
NPT1228	Organism	Streptococcus pyogenes	Streptococcus pyogenes	MIC	=	4.0	ug.mL-1	PMID[19506065]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	12.0	ug.mL-1	PMID[19770278]
NPT4066	Organism	Streptococcus mitis	Streptococcus mitis	MIC	=	0.008	ug.mL-1	PMID[19506065]
NPT1172	Organism	Streptococcus sanguinis	Streptococcus sanguinis	MIC	=	0.008	ug.mL-1	PMID[19506065]
NPT1228	Organism	Streptococcus pyogenes	Streptococcus pyogenes	Activity	=	0.06	%	PMID[19506065]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Activity	=	95.5	%	PMID[19506065]
NPT4066	Organism	Streptococcus mitis	Streptococcus mitis	Activity	=	95.5	%	PMID[19506065]
NPT1172	Organism	Streptococcus sanguinis	Streptococcus sanguinis	Activity	=	95.5	%	PMID[19506065]
NPT1228	Organism	Streptococcus pyogenes	Streptococcus pyogenes	MIC50	=	16.0	ug.mL-1	PMID[19506065]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC50	=	16.0	ug.mL-1	PMID[19506065]
NPT4066	Organism	Streptococcus mitis	Streptococcus mitis	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT1172	Organism	Streptococcus sanguinis	Streptococcus sanguinis	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT1228	Organism	Streptococcus pyogenes	Streptococcus pyogenes	MIC90	=	16.0	ug.mL-1	PMID[19506065]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC90	=	32.0	ug.mL-1	PMID[19506065]
NPT4066	Organism	Streptococcus mitis	Streptococcus mitis	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT1172	Organism	Streptococcus sanguinis	Streptococcus sanguinis	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	MIC	=	0.06	ug.mL-1	PMID[19506065]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	MIC50	=	0.25	ug.mL-1	PMID[19506065]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	>=	64.0	ug.mL-1	PMID[19770287]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	MIC90	=	1.0	ug.mL-1	PMID[19506065]
NPT3163	Organism	Acinetobacter calcoaceticus	Acinetobacter calcoaceticus	Activity	=	92.6	%	PMID[19506065]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	0.12	ug.mL-1	PMID[19506065]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	100.0	%	PMID[19506065]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC50	=	0.25	ug.mL-1	PMID[19506065]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC90	=	1.0	ug.mL-1	PMID[19506065]
NPT1465	Organism	Legionella pneumophila	Legionella pneumophila	MIC	=	0.03	ug.mL-1	PMID[19506065]
NPT1465	Organism	Legionella pneumophila	Legionella pneumophila	MIC50	=	0.12	ug.mL-1	PMID[19506065]
NPT1465	Organism	Legionella pneumophila	Legionella pneumophila	MIC90	=	1.0	ug.mL-1	PMID[19506065]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	10.8	%	PMID[19770287]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	8.0	%	PMID[19770287]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	76.5	%	PMID[19770287]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	92.0	%	PMID[19770287]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	67.0	%	PMID[19721071]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	96.0	%	PMID[19721071]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	Activity	=	83.0	%	PMID[19721071]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	0.19	ug.mL-1	PMID[19188376]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	0.38	ug.mL-1	PMID[19188376]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	8.0	ug.mL-1	PMID[18490506]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	>	8.0	ug.mL-1	PMID[18490506]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	>	40.0	ug.mL-1	PMID[21905738]
NPT564	Organism	Listeria monocytogenes	Listeria monocytogenes	IZ	=	20.0	mm	DOI[10.1007/s00044-011-9911-y]
NPT563	Organism	Escherichia coli O157:H7	Escherichia coli O157:H7	IZ	=	20.0	mm	DOI[10.1007/s00044-011-9911-y]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MBC	=	24.1	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MBC	=	28.1	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT1228	Organism	Streptococcus pyogenes	Streptococcus pyogenes	MIC	=	7.81	ug.mL-1	DOI[10.1007/s00044-012-0419-x]
NPT2913	Organism	Listeria monocytogenes ATCC 19115	Listeria monocytogenes ATCC 19115	MIC	=	18.8	ug.mL-1	PMID[23786357]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	9.4	ug.mL-1	PMID[26617967]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	2.3	ug.mL-1	PMID[23786357]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	MIC	>	32.0	ug.mL-1	PMID[24126094]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	2.0	ug.mL-1	PMID[24126094]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (acute)	=	0.0	%	PMID[15646539]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	3.0	ug.mL-1	PMID[26590102]
NPT1246	Organism	Salmonella	Salmonella	MIC	=	3.0	ug.mL-1	PMID[26590102]
NPT564	Organism	Listeria monocytogenes	Listeria monocytogenes	MIC	=	2.3	ug.mL-1	PMID[26617967]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC	=	0.6	ug.mL-1	PMID[26617967]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	<=	0.25	ug.mL-1	PMID[19015360]
NPT2710	Organism	Streptococcus agalactiae	Streptococcus agalactiae	MIC	=	32.0	ug.mL-1	PMID[30070829]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	32.0	ug.mL-1	PMID[19001116]
NPT20	Organism	Candida albicans	Candida albicans	MIC	>	20000.0	nM	DOI[10.6019/CHEMBL4513161]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	20000.0	nM	DOI[10.6019/CHEMBL4513161]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC80	=	13000.0	nM	PMID[33479610]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	>	512.0	ug.mL-1	PMID[37122541]
NPT5907	Organism	Streptococcus dysgalactiae	Streptococcus dysgalactiae	MIC	=	16.0	ug.mL-1	PMID[35675753]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	16.0	ug.mL-1	PMID[36442155]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	16.0	ug.mL-1	PMID[35339840]
NPT173	Organism	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	=	8.0	ug.mL-1	PMID[35675753]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (moderate)	=	12.0	n.a.	PMID[15646539]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (moderate)	=	23.5	%	PMID[15646539]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (granulomatous hepatitis)	=	0.0	n.a.	PMID[15646539]
NPT20529	Non-molecular	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (benign tumour)	=	0.0	n.a.	PMID[15646539]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.03	ug.mL-1	PMID[3701779]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	8.0	ug.mL-1	PMID[25981687]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	32.0	ug.mL-1	PMID[25981687]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.13	ug.mL-1	PMID[3701779]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	16.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.25	ug.mL-1	PMID[19687243]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.13	ug.mL-1	PMID[17875999]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	1.0	ug.mL-1	PMID[21905738]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	16.0	ug.mL-1	PMID[24126094]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.5	ug.mL-1	PMID[24083676]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	4.0	ug.mL-1	PMID[19349516]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	8.0	ug.mL-1	PMID[18490506]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.06	ug.mL-1	PMID[19258280]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.13	ug.mL-1	PMID[3701779]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	125.0	ug.mL-1	PMID[3701779]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	125.0	ug.mL-1	PMID[3701779]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	16.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	4.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.5	ug.mL-1	PMID[26617967]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	>	32.0	ug.mL-1	PMID[16202590]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	1.0	ug.mL-1	PMID[21905738]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.5	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	64.0	ug.mL-1	PMID[19770286]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	64.0	ug.mL-1	PMID[15808482]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	1.0	ug.mL-1	PMID[25981687]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	50.0	ug.mL-1	PMID[18285485]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	100.0	ug.mL-1	PMID[15808482]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	6.3	ug.mL-1	PMID[15808482]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	1.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	2.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	=	32.0	ug.mL-1	PMID[16202590]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.25	ug.mL-1	PMID[19188376]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	32.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	200.0	ug.mL-1	PMID[15808482]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.25	ug.mL-1	PMID[26617967]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC	=	32.0	ug.mL-1	PMID[17088477]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	67.5	%	PMID[17158943]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	36.9	%	PMID[17158943]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	83.8	%	PMID[17158943]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	6.0	ug.mL-1	PMID[17938181]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	256.0	ug.mL-1	PMID[19738007]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	64.0	ug.mL-1	PMID[24126094]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.06	ug.mL-1	PMID[17875999]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	8.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	128.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC50	=	8.0	ug.mL-1	PMID[18725441]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC90	=	16.0	ug.mL-1	PMID[18725441]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC	>	128.0	ug.mL-1	PMID[17353252]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC	=	32.0	ug.mL-1	PMID[17353252]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC	=	16.0	ug.mL-1	PMID[17353252]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC	=	8.0	ug.mL-1	PMID[17353252]
NPT2902	Organism	Mycobacterium abscessus	Mycobacterium abscessus	MIC	=	4.0	ug.mL-1	PMID[17353252]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	>	8.0	ug.mL-1	PMID[17371815]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC90	>	8.0	ug.mL-1	PMID[17371815]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	94.0	%	PMID[17371815]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	95.0	%	PMID[17371815]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	<=	2.0	ug.mL-1	PMID[17371815]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	22.0	%	PMID[17371815]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	4.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	55.0	%	PMID[17420207]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	1.95	ug.mL-1	PMID[17450125]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.62	ug.mL-1	PMID[17450125]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.62	ug.mL-1	PMID[17450125]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	0.31	ug.mL-1	PMID[17450125]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	>	62.5	ug.mL-1	PMID[17450125]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	512.0	ug.mL-1	PMID[17470656]
NPT4080	Organism	Acinetobacter sp.	Acinetobacter sp.	MIC	=	16.0	ug.mL-1	PMID[17470660]
NPT4080	Organism	Acinetobacter sp.	Acinetobacter sp.	MIC	=	8.0	ug.mL-1	PMID[17470660]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>=	2048.0	ug.mL-1	PMID[17502406]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC50	=	1.0	ug.mL-1	PMID[19917762]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	>	64.0	ug.mL-1	PMID[19917762]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	0.12	ug.mL-1	PMID[18474583]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	64.0	ug.mL-1	PMID[19770286]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	32.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	21.7	%	PMID[17682106]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	77.5	%	PMID[17682106]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	256.0	ug.mL-1	PMID[19738007]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	44.0	%	PMID[17938181]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	9.0	%	PMID[17938181]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.38	ug.mL-1	PMID[18838598]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	256.0	ug.mL-1	PMID[18838598]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	128.0	ug.mL-1	PMID[18195064]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	<=	0.06	ug.mL-1	PMID[17875999]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	128.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	32.0	ug.mL-1	PMID[24126094]
NPT5774	Organism	Citrobacter amalonaticus	Citrobacter amalonaticus	MIC	>	128.0	ug.mL-1	PMID[20000576]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	128.0	ug.mL-1	PMID[18195064]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	<	0.25	ug.mL-1	PMID[19188376]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	=	1.07	mmol/ml	PMID[20207052]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC50	=	0.53	mmol/ml	PMID[20207052]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.125	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC50	=	2.0	ug.mL-1	PMID[19506065]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC50	=	128.0	ug.mL-1	PMID[19917762]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC50	=	32.0	ug.mL-1	PMID[19917762]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	128.0	ug.mL-1	PMID[19917762]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	256.0	ug.mL-1	PMID[19917762]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	64.0	ug.mL-1	PMID[19917762]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	4.0	ug.mL-1	PMID[19917762]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	TIME	<=	0.5	hr	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	BBC	=	1.0	ug ml-1	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	TIME	=	1.0	hr	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	BBC	=	2.0	ug ml-1	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	2.0	log10CFU/ml	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	TIME	=	2.0	hr	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	2.7	log10CFU/ml	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	2.2	ug.mL-1	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	3.0	log10CFU/ml	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	3.7	log10CFU/ml	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	4.0	log10CFU/ml	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	TIME	=	4.0	hr	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	BBC	=	8.0	ug ml-1	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	TIME	=	8.0	hr	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	32.0	ug.mL-1	PMID[19805554]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC50	>	32.0	ug.mL-1	PMID[19805554]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC50	>	128.0	ug.mL-1	PMID[19805554]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC50	=	0.125	ug.mL-1	PMID[19805554]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	>	32.0	ug.mL-1	PMID[19805554]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC90	>	32.0	ug.mL-1	PMID[19805554]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC90	>	128.0	ug.mL-1	PMID[19805554]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC90	>	32.0	ug.mL-1	PMID[19506065]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	33.9	%	PMID[19933793]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	<	0.12	ug.mL-1	PMID[18474583]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	69.0	%	PMID[20047913]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	93.0	%	PMID[20047913]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	49.0	%	PMID[20047913]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>=	16.0	ug.mL-1	PMID[24126094]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	<=	1.0	ug.mL-1	PMID[21905738]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	<=	0.12	ug.mL-1	PMID[18474583]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	IZ	<	20.0	mm	PMID[18180356]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>=	128.0	ug.mL-1	PMID[18195064]
NPT4080	Organism	Acinetobacter sp.	Acinetobacter sp.	Activity	=	66.0	%	PMID[20194701]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	48.0	ug.mL-1	PMID[19770278]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	2.0	ug.mL-1	PMID[21905738]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.12	ug.mL-1	PMID[18644958]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	8.0	ug.mL-1	PMID[18490506]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	<=	2.0	ug.mL-1	PMID[21905738]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.4	ug.mL-1	PMID[18694947]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.2	ug.mL-1	PMID[18694947]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	3.0	ug.mL-1	PMID[26590102]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.19	ug.mL-1	PMID[18838598]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	<=	1.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>=	16.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.12	ug.mL-1	PMID[18474583]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	240.0	ug.mL-1	PMID[18285485]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FICI	=	4.81	n.a.	PMID[18285485]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	=	32.0	ug.mL-1	PMID[19015360]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC90	>	32.0	ug.mL-1	PMID[19015360]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC50	=	16.0	ug.mL-1	PMID[19015360]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	log10cfu	=	0.2	n.a.	PMID[18725436]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	log10cfu	=	0.86	n.a.	PMID[18725436]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	log10cfu	=	3.08	n.a.	PMID[18725436]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	log10cfu	=	2.0	n.a.	PMID[18725436]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log10cfu	=	1.69	n.a.	PMID[18725436]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log10cfu	=	2.48	n.a.	PMID[18725436]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	0.25	ug.mL-1	PMID[18725436]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	4.0	ug.mL-1	PMID[18725436]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	16.0	ug.mL-1	DOI[10.1039/C5MD00373C]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	0.125	ug.mL-1	PMID[19349516]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	50.0	%	PMID[19364876]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FC	>=	4.0	n.a.	PMID[19258280]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	16.0	ug.mL-1	PMID[24126094]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC90	=	1.0	ug.mL-1	PMID[19506065]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC50	=	0.5	ug.mL-1	PMID[19506065]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	Activity	=	68.4	%	PMID[19506065]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.12	ug.mL-1	PMID[19506065]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC90	>	128.0	ug.mL-1	PMID[19506065]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC50	=	16.0	ug.mL-1	PMID[19506065]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	=	2.0	ug.mL-1	PMID[19506065]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	Activity	=	27.3	%	PMID[19506065]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC50	=	1.0	ug.mL-1	PMID[19506065]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	<=	0.008	ug.mL-1	PMID[19506065]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	Activity	=	33.3	%	PMID[19506065]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC50	=	0.03	ug.mL-1	PMID[19506065]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	0.06	ug.mL-1	PMID[19506065]
NPT4025	Organism	Staphylococcus hominis	Staphylococcus hominis	MIC	=	0.015	ug.mL-1	PMID[19506065]
NPT1863	Organism	Staphylococcus saprophyticus	Staphylococcus saprophyticus	MIC	<=	0.008	ug.mL-1	PMID[19506065]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC50	=	2.0	ug.mL-1	PMID[19506065]
NPT4025	Organism	Staphylococcus hominis	Staphylococcus hominis	MIC50	=	16.0	ug.mL-1	PMID[19506065]
NPT1863	Organism	Staphylococcus saprophyticus	Staphylococcus saprophyticus	MIC50	=	0.015	ug.mL-1	PMID[19506065]
NPT4025	Organism	Staphylococcus hominis	Staphylococcus hominis	MIC90	=	32.0	ug.mL-1	PMID[19506065]
NPT1863	Organism	Staphylococcus saprophyticus	Staphylococcus saprophyticus	MIC90	=	0.06	ug.mL-1	PMID[19506065]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	Activity	=	16.7	%	PMID[19506065]
NPT4025	Organism	Staphylococcus hominis	Staphylococcus hominis	Activity	=	16.0	%	PMID[19506065]
NPT1863	Organism	Staphylococcus saprophyticus	Staphylococcus saprophyticus	Activity	=	54.5	%	PMID[19506065]
NPT3893	Organism	Streptococcus sp.	Streptococcus sp.	MIC	=	0.008	ug.mL-1	PMID[19506065]
NPT3893	Organism	Streptococcus sp.	Streptococcus sp.	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT3893	Organism	Streptococcus sp.	Streptococcus sp.	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT3893	Organism	Streptococcus sp.	Streptococcus sp.	Activity	=	74.0	%	PMID[19506065]
NPT2904	Organism	Streptococcus equinus	Streptococcus equinus	MIC	=	0.008	ug.mL-1	PMID[19506065]
NPT5315	Organism	Streptococcus intermedius	Streptococcus intermedius	MIC	=	0.008	ug.mL-1	PMID[19506065]
NPT4401	Organism	Streptococcus oralis	Streptococcus oralis	MIC	=	0.008	ug.mL-1	PMID[19506065]
NPT4403	Organism	Streptococcus salivarius	Streptococcus salivarius	MIC	=	0.008	ug.mL-1	PMID[19506065]
NPT2904	Organism	Streptococcus equinus	Streptococcus equinus	Activity	=	95.5	%	PMID[19506065]
NPT5315	Organism	Streptococcus intermedius	Streptococcus intermedius	Activity	=	95.5	%	PMID[19506065]
NPT4401	Organism	Streptococcus oralis	Streptococcus oralis	Activity	=	95.5	%	PMID[19506065]
NPT4403	Organism	Streptococcus salivarius	Streptococcus salivarius	Activity	=	95.5	%	PMID[19506065]
NPT2904	Organism	Streptococcus equinus	Streptococcus equinus	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT5315	Organism	Streptococcus intermedius	Streptococcus intermedius	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT4401	Organism	Streptococcus oralis	Streptococcus oralis	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT4403	Organism	Streptococcus salivarius	Streptococcus salivarius	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT2904	Organism	Streptococcus equinus	Streptococcus equinus	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT5315	Organism	Streptococcus intermedius	Streptococcus intermedius	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT4401	Organism	Streptococcus oralis	Streptococcus oralis	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT4403	Organism	Streptococcus salivarius	Streptococcus salivarius	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	96.0	ug.mL-1	PMID[19770286]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.75	ug.mL-1	PMID[19188376]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	1.5	ug.mL-1	PMID[19188376]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	24.0	ug.mL-1	PMID[19770286]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	3.0	ug.mL-1	PMID[19770286]
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC	=	0.25	ug.mL-1	PMID[19506065]
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC50	=	0.5	ug.mL-1	PMID[19506065]
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC90	=	1.0	ug.mL-1	PMID[19506065]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC	=	0.25	ug.mL-1	PMID[19506065]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC50	=	1.0	ug.mL-1	PMID[19506065]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC90	=	4.0	ug.mL-1	PMID[19506065]
NPT766	Organism	Proteus vulgaris	Proteus vulgaris	MIC	=	0.25	ug.mL-1	PMID[19506065]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC	>	8.0	ug.mL-1	PMID[24126094]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC	=	2.0	ug.mL-1	PMID[19506065]
NPT766	Organism	Proteus vulgaris	Proteus vulgaris	MIC50	=	1.0	ug.mL-1	PMID[19506065]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC50	=	8.0	ug.mL-1	PMID[19506065]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC50	>	8.0	ug.mL-1	PMID[19506065]
NPT766	Organism	Proteus vulgaris	Proteus vulgaris	MIC90	=	4.0	ug.mL-1	PMID[19506065]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	2.0	ug.mL-1	PMID[19506065]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT766	Organism	Proteus vulgaris	Proteus vulgaris	Activity	=	100.0	%	PMID[19506065]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	95.2	%	PMID[19506065]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	44.8	%	PMID[19506065]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	Activity	=	0.0	%	PMID[19506065]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	Activity	=	1.9	%	PMID[19506065]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	60.0	%	PMID[19528273]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log10cfu	=	2.9	n.a.	PMID[19528273]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	100.0	%	PMID[19721071]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	97.0	%	PMID[19721071]
NPT3495	Organism	Morganella morganii	Morganella morganii	Activity	=	100.0	%	PMID[19721071]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.38	ug.mL-1	PMID[19188376]
NPT5774	Organism	Citrobacter amalonaticus	Citrobacter amalonaticus	MIC	>	8.0	ug.mL-1	PMID[18490506]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC	=	4.0	ug.mL-1	PMID[18490506]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC	>	8.0	ug.mL-1	PMID[18490506]
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC	>	8.0	ug.mL-1	PMID[18490506]
NPT4997	Organism	Klebsiella oxytoca	Klebsiella oxytoca	MIC	=	8.0	ug.mL-1	PMID[18490506]
NPT5774	Organism	Citrobacter amalonaticus	Citrobacter amalonaticus	MIC	=	8.0	ug.mL-1	PMID[18490506]
NPT3495	Organism	Morganella morganii	Morganella morganii	MIC	=	8.0	ug.mL-1	PMID[18490506]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	1.25	ug.mL-1	PMID[21905738]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	2.5	ug.mL-1	PMID[21905738]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	5.0	ug.mL-1	PMID[21905738]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	2.0	ug.mL-1	PMID[21905738]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	FC	=	5.0	n.a.	PMID[21905738]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	IZ	=	18.0	mm	DOI[10.1007/s00044-011-9911-y]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	IZ	=	19.0	mm	DOI[10.1007/s00044-011-9911-y]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC	=	26.5	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC	=	13.7	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT1863	Organism	Staphylococcus saprophyticus	Staphylococcus saprophyticus	MBC	=	25.0	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MBC	=	50.0	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MBC	=	11.8	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MBC	=	17.3	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT19	Organism	Escherichia coli	Escherichia coli	MBC	=	74.0	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT19	Organism	Escherichia coli	Escherichia coli	MBC	=	64.3	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	15.62	ug.mL-1	DOI[10.1007/s00044-012-0419-x]
NPT19	Organism	Escherichia coli	Escherichia coli	IC50	=	15.0	nM	PMID[23786357]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	9.4	ug.mL-1	PMID[23786357]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	9.4	ug.mL-1	PMID[23786357]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	37.5	ug.mL-1	PMID[23786357]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	GI	=	100.0	%	PMID[24094434]
NPT5579	Organism	Aeromonas punctata	Aeromonas caviae	MIC	=	32.0	ug.mL-1	PMID[24126094]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC	=	8.0	ug.mL-1	PMID[24126094]
NPT4778	Organism	Streptococcus mutans UA159	Streptococcus mutans UA159	MIC	=	128.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	128.0	ug.mL-1	PMID[26617967]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MBIC	=	128.0	ug ml-1	DOI[10.1039/C2MD20162C]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	128.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	6400.0	nM	PMID[25936261]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	32.0	ug.mL-1	PMID[25981687]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	1.5	ug.mL-1	PMID[26590102]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	<=	0.25	ug.mL-1	PMID[26617967]
NPT1521	Organism	Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	MIC	>	512.0	ug.mL-1	PMID[31022550]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	=	8.0	ug.mL-1	PMID[28409644]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	1.0	ug.mL-1	PMID[27524179]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	<=	0.25	ug.mL-1	PMID[18725436]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	512.0	ug.mL-1	PMID[28409644]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Ratio	=	256.0	n.a.	PMID[28409644]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	>	128.0	ug.mL-1	PMID[19917762]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.2	ug.mL-1	PMID[27690254]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	>	256.0	ug.mL-1	PMID[29083894]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	64.0	ug.mL-1	PMID[15808482]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	32.0	ug.mL-1	PMID[24126094]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	2500.0	nM	DOI[10.6019/CHEMBL4513161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	20000.0	nM	DOI[10.6019/CHEMBL4513161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	1250.0	nM	DOI[10.6019/CHEMBL4513161]
NPT20950	Cell line	Erythrocyte	n.a.	HC10	>	20.0	uM	DOI[10.6019/CHEMBL4513161]
NPT5485	Organism	Mycobacterium leprae	Mycobacterium leprae	Activity	=	28.7	%	PMID[31103404]
NPT5485	Organism	Mycobacterium leprae	Mycobacterium leprae	Activity	=	37.0	%	PMID[31103404]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	INH	=	4.0	ug ml-1	PMID[32033878]
NPT19	Organism	Escherichia coli	Escherichia coli	INH	=	16.0	ug ml-1	PMID[32033878]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC80	=	1600.0	nM	PMID[33479610]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC80	=	780.0	nM	PMID[33479610]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	4096.0	ug.mL-1	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	2048.0	ug.mL-1	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	1024.0	ug.mL-1	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FIC	=	0.5	n.a.	PMID[31022550]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	2.0	ug.mL-1	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FICI	=	1.5	n.a.	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FICI	=	1.0	n.a.	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FICI	<=	1.5	n.a.	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FICI	<=	1.0	n.a.	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FICI	=	1.125	n.a.	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FICI	=	1.25	n.a.	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FIC	<=	0.5	n.a.	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FIC	=	0.125	n.a.	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FIC	=	0.25	n.a.	PMID[31022550]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC90	=	1.0	ug.mL-1	PMID[36795859]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Inhibition	n.a.	n.a.	%	PMID[37798258]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	4.0	ug.mL-1	PMID[34569791]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	n.a.	n.a.	n.a.	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	n.a.	n.a.	n.a.	PMID[37978953]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	10.0	ug.mL-1	PMID[34951310]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.5	ug.mL-1	PMID[34671738]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	16.0	ug.mL-1	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	1.0	ug.mL-1	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log(activity)	=	1.5	n.a.	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	2.0	%	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log(activity)	=	3.0	n.a.	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FC	=	4.0	n.a.	PMID[33848161]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	8.0	ug.mL-1	PMID[35339840]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.25	ug.mL-1	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.5	ug.mL-1	PMID[35339840]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	32.0	ug.mL-1	PMID[35675753]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	8.0	ug.mL-1	PMID[34671738]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.5	ug.mL-1	PMID[35339840]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FC	=	1.0	n.a.	PMID[34569791]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	2.0	ug.mL-1	PMID[34671738]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	6250.0	nM	PMID[37593580]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	12500.0	nM	PMID[37593580]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.5	ug.mL-1	PMID[37798258]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log(activity)	=	4110000.0	n.a.	PMID[33848161]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	8.0	ug.mL-1	PMID[35675753]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBIC90	=	0.5	ug ml-1	PMID[37798258]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log(activity)	=	1.0	n.a.	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	<	0.125	ug.mL-1	PMID[33848161]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	8.0	ug.mL-1	PMID[35675753]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.5	ug.mL-1	PMID[36442155]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	5.0	ug.mL-1	PMID[34951310]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	n.a.	n.a.	n.a.	PMID[37798258]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	512.0	ug.mL-1	PMID[37122541]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	250000.0	CFU/ml	PMID[33848161]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	2.0	ug.mL-1	PMID[34671738]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Inhibition	=	92.0	%	PMID[34542288]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	8.0	ug.mL-1	PMID[36442155]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	8.0	ug.mL-1	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log(activity)	=	2.5	n.a.	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	0.5	ug.mL-1	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	n.a.	n.a.	n.a.	PMID[34520957]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	n.a.	n.a.	n.a.	PMID[37874867]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	1.78	%	PMID[37874867]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log(activity)	=	2.0	n.a.	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	2.0	ug.mL-1	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FC	=	16.0	n.a.	PMID[33848161]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100000.0	nM	PMID[37593580]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	700.0	nM	PMID[30404451]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	5.77	%	PMID[37874867]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.5	ug.mL-1	PMID[34671738]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FC	=	64.0	n.a.	PMID[37798258]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBIC50	=	0.5	ug ml-1	PMID[37798258]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FC	=	2.0	n.a.	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	1.0	ug.mL-1	PMID[38516601]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	FC	=	2.0	n.a.	PMID[34569791]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	8.0	ug.mL-1	PMID[34569791]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Activity	=	4.64	log10CFU/ml	PMID[36510819]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	log(activity)	=	0.5	n.a.	PMID[33848161]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	2.0	ug.mL-1	PMID[38516601]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	1.0	ug.mL-1	PMID[35675753]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	32.0	ug.mL-1	PMID[33848161]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	=	2000.0	nM	PMID[34542288]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	=	1560.0	nM	PMID[37593580]
NPT5774	Organism	Citrobacter amalonaticus	Citrobacter amalonaticus	MIC	>	512.0	ug.mL-1	PMID[37122541]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBIC50	=	2.0	uM	PMID[34542288]
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	32.0	ug.mL-1	PMID[35675753]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	GI	n.a.	n.a.	n.a.	PMID[38362867]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	0.5	ug.mL-1	PMID[36442155]
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	=	8.0	ug.mL-1	PMID[34671738]
NPT2	Others	Unspecified	n.a.	Potency	n.a.	1012.4	nM	PubChem BioAssay data set
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	2.0	ug.mL-1	PMID[3701779]
NPT2	Others	Unspecified	n.a.	Kd	=	1680.0	nM	PMID[11677142]
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC50	=	16.0	ug.mL-1	PMID[17353252]
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC90	=	32.0	ug.mL-1	PMID[17353252]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	32.0	ug.mL-1	PMID[18591275]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	0.75	ug.mL-1	PMID[19884373]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	4.0	ug.mL-1	PMID[18591275]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	3.0	ug.mL-1	PMID[17420217]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	6.0	ug.mL-1	PMID[17420217]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	16.0	ug.mL-1	PMID[24126094]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	8.0	ug.mL-1	DOI[10.1039/C5MD00377F]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	24.0	ug.mL-1	PMID[17420217]
NPT1531	Organism	Enterococcus faecium	Enterococcus faecium	MIC	>	62.5	ug.mL-1	PMID[17450125]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	16.0	ug.mL-1	PMID[24126094]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	512.0	ug.mL-1	PMID[17785513]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	=	0.5	ug.mL-1	PMID[24083676]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	=	1.0	ug.mL-1	PMID[24083676]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	>	128.0	ug.mL-1	PMID[20000576]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	6250.0	nM	PMID[20044260]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	25000.0	nM	PMID[20044260]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	200000.0	nM	PMID[20044260]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	400000.0	nM	PMID[20044260]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	1.0	ug.mL-1	DOI[10.1039/C5MD00377F]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	1.5	ug.mL-1	PMID[19884373]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	2.0	ug.mL-1	PMID[18591275]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	12.0	ug.mL-1	PMID[19884373]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	96.0	ug.mL-1	PMID[19884373]
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC50	=	4.0	ug.mL-1	PMID[18725441]
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC90	=	16.0	ug.mL-1	PMID[18725441]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	64.0	ug.mL-1	PMID[18505859]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	<=	1.0	ug.mL-1	DOI[10.1039/C5MD00377F]
NPT1531	Organism	Enterococcus faecium	Enterococcus faecium	MIC90	>	128.0	ug.mL-1	PMID[19506065]
NPT1531	Organism	Enterococcus faecium	Enterococcus faecium	MIC50	>	128.0	ug.mL-1	PMID[19506065]
NPT1531	Organism	Enterococcus faecium	Enterococcus faecium	MIC	=	2.0	ug.mL-1	PMID[19506065]
NPT1477	Organism	Staphylococcus haemolyticus	Staphylococcus haemolyticus	MIC	=	0.015	ug.mL-1	PMID[19506065]
NPT1477	Organism	Staphylococcus haemolyticus	Staphylococcus haemolyticus	MIC50	=	2.0	ug.mL-1	PMID[19506065]
NPT1477	Organism	Staphylococcus haemolyticus	Staphylococcus haemolyticus	MIC90	=	32.0	ug.mL-1	PMID[19506065]
NPT1477	Organism	Staphylococcus haemolyticus	Staphylococcus haemolyticus	Activity	=	26.7	%	PMID[19506065]
NPT5314	Organism	Streptococcus constellatus	Streptococcus constellatus	MIC	=	0.008	ug.mL-1	PMID[19506065]
NPT5314	Organism	Streptococcus constellatus	Streptococcus constellatus	Activity	=	95.5	%	PMID[19506065]
NPT5314	Organism	Streptococcus constellatus	Streptococcus constellatus	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT5314	Organism	Streptococcus constellatus	Streptococcus constellatus	MIC90	>	8.0	ug.mL-1	PMID[19506065]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	0.12	ug.mL-1	PMID[19506065]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	<=	0.03	ug.mL-1	PMID[19506065]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC50	=	4.0	ug.mL-1	PMID[19506065]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC50	=	0.06	ug.mL-1	PMID[19506065]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC90	>	64.0	ug.mL-1	PMID[19506065]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC90	=	0.5	ug.mL-1	PMID[19506065]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Activity	=	60.4	%	PMID[19506065]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	Activity	=	94.0	%	PMID[19506065]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	MIC	=	0.25	ug.mL-1	PMID[19506065]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	MIC50	=	0.5	ug.mL-1	PMID[19506065]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	MIC90	=	1.0	ug.mL-1	PMID[19506065]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	=	0.25	ug.mL-1	PMID[19506065]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	Activity	=	100.0	%	PMID[19506065]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC50	=	0.5	ug.mL-1	PMID[19506065]
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC90	=	8.0	ug.mL-1	PMID[19506065]
NPT1121	Organism	Moraxella catarrhalis	Moraxella catarrhalis	MIC	=	0.015	ug.mL-1	PMID[19506065]
NPT1121	Organism	Moraxella catarrhalis	Moraxella catarrhalis	Activity	=	100.0	%	PMID[19506065]
NPT1121	Organism	Moraxella catarrhalis	Moraxella catarrhalis	MIC50	=	0.03	ug.mL-1	PMID[19506065]
NPT1121	Organism	Moraxella catarrhalis	Moraxella catarrhalis	MIC90	=	0.03	ug.mL-1	PMID[19506065]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	0.12	ug.mL-1	PMID[19506065]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC50	=	0.5	ug.mL-1	PMID[19506065]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC90	=	1.0	ug.mL-1	PMID[19506065]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	Activity	=	100.0	%	PMID[19506065]
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC	=	25.0	ug.mL-1	PMID[19581465]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	<	0.25	ug.mL-1	PMID[18591275]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	0.5	ug.mL-1	PMID[18591275]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Activity	=	61.2	%	PMID[18725452]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	>	8.0	ug.mL-1	PMID[18490506]
NPT5757	Organism	Citrobacter koseri	Citrobacter koseri	MIC	=	8.0	ug.mL-1	PMID[18490506]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	8.0	ug.mL-1	DOI[10.1039/C5MD00377F]
NPT1248	Organism	Serratia marcescens	Serratia marcescens	MIC	=	8.0	ug.mL-1	PMID[18490506]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	<=	1.0	ug.mL-1	PMID[24083676]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	=	8.0	ug.mL-1	PMID[20921306]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	=	2.0	ug.mL-1	PMID[20921306]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	=	4.0	ug.mL-1	PMID[20921306]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	=	16.0	ug.mL-1	PMID[20921306]
NPT20596	Phenotype	Hepatotoxicity	n.a.	Composite Activity - Active	=	0.0	n.a.	PMID[16472241]
NPT20596	Phenotype	Hepatotoxicity	n.a.	Composite Activity - Marginal	=	0.0	n.a.	PMID[16472241]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_bilirubinemia	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_cholecystitis	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_cholelithiasis	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_cirrhosis	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_hepatic failure	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_hepatic necrosis	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_hepatomegaly	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_jaundice	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_liver fatty	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_liver function tests abnormal	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_Combined Scores	=	0.0	n.a.	PMID[22194678]
NPT314	Organism	Bacillus cereus	Bacillus cereus	IZ	=	19.0	mm	DOI[10.1007/s00044-011-9911-y]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MBC	=	78.1	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MBC	=	83.3	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MBC	=	68.0	mg/L	DOI[10.1007/s00044-011-9933-5]
NPT1277	Organism	Staphylococcus epidermidis ATCC 12228	Staphylococcus epidermidis ATCC 12228	MIC	=	0.3	ug.mL-1	PMID[23786357]
NPT314	Organism	Bacillus cereus	Bacillus cereus	MIC	=	75.0	ug.mL-1	PMID[23786357]
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	0.6	ug.mL-1	PMID[23786357]
NPT1843	Organism	Aeromonas hydrophila	Aeromonas hydrophila	MIC	=	16.0	ug.mL-1	PMID[24126094]
NPT1277	Organism	Staphylococcus epidermidis ATCC 12228	Staphylococcus epidermidis ATCC 12228	MIC	<	1.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT1243	Organism	Shigella sonnei	Shigella sonnei	MIC	=	32.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT1243	Organism	Shigella sonnei	Shigella sonnei	MIC	=	16.0	ug.mL-1	DOI[10.1039/C2MD20162C]
NPT2	Others	Unspecified	n.a.	Ki	=	59900.0	nM	PMID[24709560]
NPT314	Organism	Bacillus cereus	Bacillus cereus	MIC	=	9.4	ug.mL-1	PMID[26617967]
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	>=	128.0	ug.mL-1	PMID[26617967]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	32.0	ug.mL-1	PMID[18591275]
NPT1531	Organism	Enterococcus faecium	Enterococcus faecium	MIC	=	8.0	ug.mL-1	PMID[28409644]
NPT1531	Organism	Enterococcus faecium	Enterococcus faecium	MIC	>	256.0	ug.mL-1	PMID[29083894]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	6.25	ug.mL-1	PMID[28291943]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MBC99.9	>	25.0	ug ml-1	PMID[28291943]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	>	25.0	ug.mL-1	PMID[28291943]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MBC99.9	=	12.5	ug ml-1	PMID[28291943]
NPT2898	Organism	Acinetobacter lwoffii	Acinetobacter lwoffii	MIC	<	0.25	ug.mL-1	PMID[30282323]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	FC	=	512.0	n.a.	PMID[31557020]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	0.25	ug.mL-1	PMID[18591275]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	2500.0	nM	DOI[10.6019/CHEMBL4513161]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC80	=	3100.0	nM	PMID[33479610]
NPT1531	Organism	Enterococcus faecium	Enterococcus faecium	MIC	=	16.0	ug.mL-1	PMID[31022550]
NPT26933	Organism	Cronobacter sakazakii	Cronobacter sakazakii	MIC	=	16.0	ug.mL-1	PMID[35675753]
NPT29356	Organism	Klebsiella aerogenes	Klebsiella aerogenes	MIC	>	512.0	ug.mL-1	PMID[37122541]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	0.5	ug.mL-1	PMID[38516601]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	MIC	=	0.5	ug.mL-1	PMID[34671738]
NPT1531	Organism	Enterococcus faecium	Enterococcus faecium	MIC	=	32.0	ug.mL-1	PMID[35675753]
NPT1531	Organism	Enterococcus faecium	Enterococcus faecium	MIC	=	16.0	ug.mL-1	PMID[34671738]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Inhibition	=	100.0	%	PMID[36877255]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_liver disease	=	0.0	n.a.	PMID[22194678]

In vivo activity

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT32	Organism	Mus musculus	Mus musculus	fc max	=	19.07	mg/L	PMID[17470655]
NPT32	Organism	Mus musculus	Mus musculus	fAUC	=	42960.0	ng.hr.mL-1	PMID[17470655]
NPT32	Organism	Mus musculus	Mus musculus	MTD	=	60.0	mg Kg-1	PMID[19528273]
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	99.7	%	PMID[27690420]
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	83.2	%	PMID[27690420]
NPT1548	Organism	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	Mortality	=	66.7	%	PMID[17470655]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Mortality	=	60.0	%	PMID[17470655]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Survival	=	18.1	%	PMID[37978953]
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	Survival	=	46.7	%	PMID[37978953]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_elevated liver function tests	=	0.0	n.a.	PMID[22194678]
NPT20596	Phenotype	Hepatotoxicity	n.a.	HepSE_hepatitis	=	0.0	n.a.	PMID[22194678]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	25.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	36400.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	233.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	81.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	144.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	105.6	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	692.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	303.2	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	5.6	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1254.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	105.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	22.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	114.8	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.52	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	147.0	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	61000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	10.6	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.032	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.11	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	6.63	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.14	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	1.17	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.38	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	1.28	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7450000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	45.74	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	147200.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	8110.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	81.3	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	19.76	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	321600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	61.38	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.76	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	14.9	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1322400.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	31.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	36600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	228.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	79.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	112.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	107.0	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	570.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	233.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	5.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1244.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	106.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	24.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	105.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.34	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	149.2	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	64800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	9.4	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.13	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.14	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	13.53	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.4	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	2.33	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.72	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.86	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7740000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	45.98	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	138600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	16610.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	81.34	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	18.0	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	302200.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	59.4	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	2.46	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	14.14	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1445500.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	30.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	37100.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	186.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	78.2	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	142.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	105.4	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	449.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	334.3	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	6.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1472.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	123.1	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	9.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	100.1	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.57	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	149.5	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.1	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	66600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	12.6	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.091	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	9.91	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.21	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	1.56	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.77	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.92	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	8210000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	47.53	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	156500.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	11910.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	83.34	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	19.07	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	329300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	57.9	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.68	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	12.97	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1323800.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	32.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	34200.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	217.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	80.2	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	148.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	109.8	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	584.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	257.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	5.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1272.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	84.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	17.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	102.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.26	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	151.2	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	1.4	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	58400.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	9.8	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.078	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.12	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	8.04	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	0.92	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.78	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	1.32	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7610000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	45.66	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	152200.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	9410.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	84.78	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	20.04	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	333800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	60.02	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	2.34	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	10.36	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1436600.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	28.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	35400.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	192.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	85.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	152.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	108.8	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	558.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	214.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	7.4	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1092.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	103.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	33.8	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	98.8	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.88	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	150.8	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	62800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	9.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.12	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.06	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	7.97	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.18	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	0.97	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	1.16	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.6	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7910000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	46.26	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	9340.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	85.08	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	19.22	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	329000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	58.56	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	2.0	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	10.74	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1248400.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	28.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	35600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	137.2	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	79.3	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	163.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	108.2	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	594.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	132.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	6.8	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	83.6	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	12.4	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	83.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.48	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	152.3	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	1.8	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	65300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	9.6	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.11	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	11.02	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.27	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	2.01	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.75	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	1.01	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	8160000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	47.35	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	155600.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	13610.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	82.08	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	19.08	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	328700.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	58.02	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.93	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	13.77	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1300900.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	20.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	43500.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	86.75	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	170.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	29000000.0	nM	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	106.25	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	512.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	384.75	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	4.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1287.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	145.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	13.25	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	118.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.58	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	151.0	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	3.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	19.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.35	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.62	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7260000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	47.97	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	153800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	8680.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	86.77	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	21.18	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	320500.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	66.15	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.57	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	9.53	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1786000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	300.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	24.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	40500.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	204.75	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	86.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	127.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	25000000.0	nM	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	106.5	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	517.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	410.25	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	4.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1130.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	267.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	10.0	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	124.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.8	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	148.5	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	1.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	61700.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	15.7	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.6	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.68	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7480000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	151700.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	12190.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	85.22	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	20.27	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	330000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	61.53	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.38	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	10.35	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1359250.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	41700.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	314.25	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	91.75	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	152.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	25750000.0	nM	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	108.25	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	560.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	601.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1217.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	185.75	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	8.25	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	120.3	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.68	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	152.0	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	3.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	63800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	18.2	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.42	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.7	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7290000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	46.27	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	149200.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	6740.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	87.65	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	20.48	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	322500.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	63.45	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.52	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	8.62	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1523000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	27.25	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	38800.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	236.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	89.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	132.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	24000000.0	nM	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	105.5	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	557.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	349.5	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	5.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1182.5	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	195.25	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	12.25	U.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	135.8	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.65	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	149.0	mEq.L-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	60000.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.57	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.42	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7690000.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	47.83	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	156300.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	11690.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	86.55	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	20.3	pg	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	326700.0	ug.mL-1	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	62.25	fL	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	2.05	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	9.38	%	DOI[10.6019/CHEMBL3885881]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1334500.0	cells.uL-1	DOI[10.6019/CHEMBL3885881]
NPT747	Organism	Acinetobacter baumannii	Acinetobacter baumannii	Survival	=	100.0	%	PMID[28291943]

Experimental ADME

Experiment Model	Experiment Tissue	ADME Type	ADME Relation	ADME Value	ADME Unit	Reference
Homo sapiens	n.a.	Fu	=	1.0	n.a.	PMID[18426954]

Experimental Toxicity

Quantitative toxicity

Experiment Model	Experiment Organism	Toxicity Type	Toxicity Relation	Toxicity Value	Toxicity Unit	Reference

Common Abbreviations:
LC: Lethal Concentration; LD: Lethal Dose; LT:Lethal Time; NOAEL: No-observed-adverse-effect Level; BMDL: Benchmark Dose Lower Confidence Limit; BMD: Benchmark Dose; BMC:Benchmark Concentration; LOAEL: Lowest Observed Adverse Effect Level; RfD:Reference Dose; RfC:Reference Concentration; MRL: Minimal Risk Level; MEG: Maximum Exposure Guideline; PAC: Protective Action Criteria

Categorical toxicity labels

Hepatotoxicity	Carcinogenicity	Mutagenicity	Cardiotoxicity	Respiratory Toxicity	Eye Irritation	Endocrine Disruption

Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP toxicity records from domain-specific databases. These databases include:
☉ ToxValDB: a curated database that compiles quantitative toxicity values for chemicals from diverse public sources to support toxicological research and risk assessment.
☉ TOXRIC: a comprehensive, free-to-access, online database providing toxicological/feature data. The toxicity labels are retrieved from this database. [PMID: 36400569]

Chemically structural similarity

Similar Active Natural Products in NPASS

Top-200 similar NPs were calculated against the active-NP-set (includes approximately 50,000 NPs with experimentally-derived bioactivity available in NPASS)

Similarity is measured using the Tanimoto coefficient (Tc) , which compares the binary fingerprints of two molecules. Tc is calculated as the intersection divided by the union of '1' bits in the fingerprints, ranging from 0 to 1, with 1 indicating highest similarity.

● The left chart: Distribution of similarity level between NPC314408 and all remaining natural products in the NPASS database.
● The right table: Most similar natural products (Tc>=0.5 or Top200).

range	Tanimoto Coefficient
0-0.1	35766
0.1-0.2	13933
0.2-0.3	132
0.3-0.4	14
0.4-0.5	8
0.5-0.6	1
0.6-0.7	3
0.7-0.8	0
0.8-0.85	0
0.85-0.9	0
0.9-0.95	0
0.95-1	0

Similarity Score	Similarity Level	Natural Product ID
0.7143	Intermediate Similarity	NPC611754
0.6557	Remote Similarity	NPC607776
0.6491	Remote Similarity	NPC43850
0.6491	Remote Similarity	NPC485811
0.5968	Remote Similarity	NPC477060

Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

● The left chart: Distribution of similarity level between NPC314408 and all drugs/candidates.
● The right table: Most similar clinical/approved drugs (Tc>=0.5 or Top200).

range	Tanimoto Coefficient
0-0.1	7922
0.1-0.2	1181
0.2-0.3	24
0.3-0.4	11
0.4-0.5	7
0.5-0.6	1
0.6-0.7	1
0.7-0.8	0
0.8-0.85	0
0.85-0.9	0
0.9-0.95	1
0.95-1	2

Similarity Score	Similarity Level	Drug ID	Developmental Stage
1.0	High Similarity	NPD3208	Phase 4
1.0	High Similarity	NPD3209	Approved
0.9057	High Similarity	NPD3207	Approved
0.6491	Remote Similarity	NPD3203	Phase 4
0.5968	Remote Similarity	NPD3201	Approved

Bioactivity similarity

Similar Natural Products in NPASS

Similarity level is defined by Bioactivity similarity was calculated based on bioactivity descriptors of compounds. The bioactivity descriptors were calculated by a recently developed AI algorithm Chemical Checker (CC) [Nature Biotechnology, 38:1087–1096, 2020; Nature Communications, 12:3932, 2021], which evaluated bioactivity similarities at five levels:
☉ A: chemistry similarity;
☉ B: biological targets similarity;
☉ C: networks similarity;
☉ D: cell-based bioactivity similarity;
☉ E: similarity based on clinical data.
Those 5 categories of CC bioactivity descriptors were calculated and then subjected to manifold projection using UMAP algorithm, to project all NPs on a 2-Dimensional space. The current NP was highlighted with a small circle in the 2-D map. Below figures: left-to-right, A-to-E.

A: chemistry similarity

B: biological targets similarity

C: networks similarity

D: cell-based bioactivity similarity

E: similarity based on clinical data