| Target ID | Target Name | Target Organism | # Natural Product | # Activity Record |
|---|---|---|---|---|
| NPT3910 | ADAM17 | Homo sapiens | 7 | 11 |
| NPT469 | Cathepsin L | Homo sapiens | 12 | 14 |
| NPT200 | SARS coronavirus 3C-like proteinase | SARS coronavirus | 9 | 35 |
| NPT200 | SARS coronavirus 3C-like proteinase | SARS coronavirus | 9 | 35 |
| NPT201 | Papain | Carica papaya | 19 | 22 |
| NPT6642 | Plasmepsin 2 | Plasmodium falciparum | 1 | 2 |
| NPT1217 | Botulinum neurotoxin type A | Clostridium botulinum | 14 | 27 |
| NPT6425 | Kallikrein 8 | Homo sapiens | 2 | 4 |
| NPT2785 | Tryptase beta-1 | Homo sapiens | 5 | 7 |
| NPT1323 | Botulinum neurotoxin type A | Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) | 4 | 10 |
| NPT5835 | Methionine aminopeptidase | Escherichia coli K-12 | 1 | 2 |
| NPT3968 | Leucine aminopeptidase | Homo sapiens | 3 | 8 |
| NPT3968 | Leucine aminopeptidase | Homo sapiens | 3 | 8 |
| NPT670 | Thrombin | Homo sapiens | 44 | 63 |
| NPT4016 | Matrix metalloproteinase 7 | Homo sapiens | 5 | 6 |
| NPT4015 | Matrix metalloproteinase 14 | Homo sapiens | 10 | 11 |
| NPT479 | Aminopeptidase B | Rattus norvegicus | 2 | 5 |
| NPT215 | Cathepsin B | Mus musculus | 2 | 2 |
| NPT214 | Cathepsin B | Homo sapiens | 15 | 42 |
| NPT4655 | Coagulation factor IX | Homo sapiens | 6 | 6 |
| NPT6254 | Coagulation factor VII | Homo sapiens | 7 | 9 |
| NPT6326 | Vitamin K-dependent protein C | Homo sapiens | 2 | 4 |
| NPT6321 | Kallikrein 12 | Homo sapiens | 1 | 2 |
| NPT5220 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Homo sapiens | 1 | 2 |
| NPT5645 | Carboxypeptidase A1 | Homo sapiens | 8 | 8 |
| NPT1547 | Cathepsin D | Homo sapiens | 9 | 18 |
| NPT444 | Ubiquitin carboxyl-terminal hydrolase 1 | Homo sapiens | 394 | 452 |
| NPT6520 | Matrix metalloproteinase 11 | Homo sapiens | 2 | 3 |
| NPT4644 | Glutamate carboxypeptidase II | Rattus norvegicus | 2 | 2 |
| NPT6648 | Kallikrein 14 | Homo sapiens | 1 | 2 |
| NPT5079 | Transmembrane protease serine 6 | Homo sapiens | 1 | 2 |
| NPT4897 | Insulin-degrading enzyme | Homo sapiens | 4 | 8 |
| NPT5077 | Cathepsin B | Bos taurus | 8 | 8 |
| NPT5076 | Plasminogen | Bos taurus | 1 | 1 |
| NPT6352 | Kallikrein 13 | Homo sapiens | 1 | 2 |
| NPT1553 | Aminopeptidase N | Sus scrofa | 8 | 43 |
| NPT1554 | Neprilysin | Rattus norvegicus | 4 | 11 |
| NPT2929 | Pancreatic elastase | Sus scrofa | 4 | 4 |
| NPT4211 | Caspase-8 | Homo sapiens | 5 | 6 |
| NPT1226 | Caspase-7 | Homo sapiens | 56 | 67 |
| NPT5554 | Botulinum neurotoxin type E | Clostridium botulinum | 1 | 1 |
| NPT5802 | Cysteine protease ATG4B | Homo sapiens | 1 | 1 |
| NPT2682 | Alpha-chymotrypsin | Bos taurus | 11 | 17 |
| NPT2664 | Ubiquitin carboxyl-terminal hydrolase 4 | Homo sapiens | 1 | 1 |
| NPT2663 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | Homo sapiens | 2 | 2 |
| NPT2662 | Ubiquitin carboxyl-terminal hydrolase isozyme L3 | Homo sapiens | 1 | 1 |
| NPT2661 | Ubiquitin carboxyl-terminal hydrolase 8 | Homo sapiens | 1 | 1 |
| NPT2265 | Caspase-9 | Homo sapiens | 4 | 5 |
| NPT3545 | Matrix metalloproteinase 9 | Mus musculus | 3 | 3 |
| NPT6208 | Lysosomal Pro-X carboxypeptidase | Homo sapiens | 2 | 2 |
| NPT5086 | Hepatocyte growth factor activator | Homo sapiens | 1 | 1 |
| NPT1569 | Chymotrypsin C | Homo sapiens | 10 | 12 |
| NPT1568 | Trypsin I | Bos taurus | 11 | 12 |
| NPT1584 | Cytosol aminopeptidase | Sus scrofa | 2 | 2 |
| NPT1584 | Cytosol aminopeptidase | Sus scrofa | 2 | 2 |
| NPT6590 | Ubiquitin carboxyl-terminal hydrolase 21 | Homo sapiens | 1 | 1 |
| NPT2979 | Carboxypeptidase A1 | Bos taurus | 4 | 4 |
| NPT5879 | Neprilysin | Homo sapiens | 1 | 5 |
| NPT5878 | Endothelin-converting enzyme 1 | Homo sapiens | 1 | 14 |
| NPT6373 | Complement C1s | Homo sapiens | 1 | 2 |
| NPT6575 | Caspase-4 | Homo sapiens | 2 | 3 |
| NPT5527 | Botulinum neurotoxin type B | Clostridium botulinum | 1 | 1 |
| NPT3983 | CAAX prenyl protease 1 | Saccharomyces cerevisiae S288c | 2 | 2 |
| NPT6213 | Prenyl protein specific protease | Homo sapiens | 2 | 2 |
| NPT4181 | Xaa-Pro dipeptidase | Homo sapiens | 2 | 3 |
| NPT4184 | Dipeptidyl peptidase IV | Sus scrofa | 1 | 2 |
| NPT1591 | Prolyl endopeptidase | Homo sapiens | 16 | 29 |
| NPT1592 | Dipeptidyl peptidase IV | Homo sapiens | 43 | 50 |
| NPT6588 | Leukocyte proteinase 3 | Homo sapiens | 1 | 2 |
| NPT6580 | Granzyme B | Homo sapiens | 1 | 2 |
| NPT4527 | Enteropeptidase | Homo sapiens | 1 | 1 |
| NPT6363 | Elastase 1 | Homo sapiens | 3 | 7 |
| NPT5912 | D-alanyl-D-alanine dipeptidase | Enterococcus faecium | 1 | 1 |
| NPT6262 | Dipeptidyl peptidase IV | Rattus norvegicus | 4 | 12 |
| NPT150 | Anthrax lethal factor | Bacillus anthracis | 234 | 267 |
| NPT1485 | Collagenase | Porphyromonas gingivalis | 2 | 8 |
| NPT979 | Caspase-3 | Homo sapiens | 15 | 26 |
| NPT4886 | Ubiquitin carboxyl-terminal hydrolase 7 | Homo sapiens | 3 | 3 |
| NPT6487 | Dipeptidyl peptidase IX | Homo sapiens | 2 | 3 |
| NPT6563 | Prolyl endopeptidase | Elizabethkingia meningoseptica | 1 | 1 |
| NPT6391 | Cathepsin Z | Homo sapiens | 2 | 3 |
| NPT5921 | Zinc aminopeptidase | Plasmodium falciparum FcB1/Columbia | 1 | 2 |
| NPT5925 | Aminopeptidase N | Mus musculus | 1 | 2 |
| NPT5924 | Cytosol aminopeptidase | Bos taurus | 1 | 2 |
| NPT5924 | Cytosol aminopeptidase | Bos taurus | 1 | 2 |
| NPT5910 | D,D-dipeptidase | Enterococcus faecium | 1 | 3 |
| NPT4432 | Presenilin 1 | Homo sapiens | 1 | 3 |
| NPT567 | Matrix metalloproteinase 3 | Homo sapiens | 59 | 73 |
| NPT569 | Matrix metalloproteinase 8 | Homo sapiens | 38 | 39 |
| NPT568 | Matrix metalloproteinase-2 | Homo sapiens | 65 | 97 |
| NPT4852 | Puromycin-sensitive aminopeptidase | Homo sapiens | 1 | 1 |
| NPT4898 | Tripeptidyl aminopeptidase | Rattus norvegicus | 3 | 3 |
| NPT4856 | Proteasome Macropain subunit | Saccharomyces cerevisiae S288c | 1 | 1 |
| NPT4857 | Proteasome component C5 | Saccharomyces cerevisiae S288c | 1 | 1 |
| NPT4855 | Proteasome Macropain subunit PRE2 | Saccharomyces cerevisiae S288c | 1 | 1 |
| NPT6497 | Kallikrein 4 | Homo sapiens | 1 | 2 |
| NPT6166 | Neprilysin | Mus musculus | 1 | 1 |
| NPT6386 | Dipeptidyl peptidase I | Homo sapiens | 2 | 3 |
| NPT69 | Matrix metalloproteinase-1 | Homo sapiens | 46 | 55 |
| NPT6544 | Renin | Homo sapiens | 1 | 2 |
| NPT5930 | Cathepsin S | Homo sapiens | 3 | 4 |
| NPT2534 | Thrombin | Bos taurus | 10 | 21 |
| NPT2533 | Coagulation factor X | Homo sapiens | 10 | 17 |
| NPT4178 | M1-family aminopeptidase | Plasmodium falciparum 3D7 | 7 | 7 |
| NPT6515 | ADAM9 | Homo sapiens | 4 | 6 |
| NPT1720 | Plasminogen | Homo sapiens | 25 | 40 |
| NPT1727 | Acrosin | Homo sapiens | 22 | 27 |
| NPT4404 | CAAX prenyl protease 2 | Saccharomyces cerevisiae S288c | 3 | 3 |
| NPT606 | Trypsin I | Homo sapiens | 4 | 10 |
| NPT607 | Beta-chymotrypsin | Homo sapiens | 7 | 12 |
| NPT601 | Cathepsin L2 | Homo sapiens | 12 | 20 |
| NPT280 | Matrix metalloproteinase 9 | Homo sapiens | 58 | 73 |
| NPT4971 | Kallikrein 5 | Homo sapiens | 3 | 6 |
| NPT4571 | Tetanus toxin | Clostridium tetani (strain Massachusetts / E88) | 1 | 1 |
| NPT5897 | Cystinyl aminopeptidase | Rattus norvegicus | 2 | 4 |
| NPT5896 | Aminopeptidase A | Homo sapiens | 1 | 1 |
| NPT1654 | Urokinase-type plasminogen activator | Homo sapiens | 8 | 11 |
| NPT5092 | Proteasome subunit beta type-8 | Homo sapiens | 1 | 1 |
| NPT4380 | Kallikrein 7 | Homo sapiens | 3 | 4 |
| NPT4417 | Elastase 1 | Sus scrofa | 4 | 5 |
| NPT5075 | Plasma kallikrein | Homo sapiens | 3 | 5 |
| NPT40 | 72 kDa type IV collagenase | Rattus norvegicus | 9 | 9 |
| NPT45 | Ubiquitin carboxyl-terminal hydrolase 2 | Homo sapiens | 78 | 85 |
| NPT5883 | ATP-dependent Clp protease proteolytic subunit | Escherichia coli (strain K12) | 2 | 2 |
| NPT5880 | Endothelin-converting enzyme 1 | Bos taurus | 1 | 1 |
| NPT5881 | Neprilysin | Oryctolagus cuniculus | 1 | 3 |
| NPT5374 | Methionine aminopeptidase 1 | Homo sapiens | 3 | 5 |
| NPT5373 | Methionine aminopeptidase 2 | Homo sapiens | 4 | 6 |
| NPT5087 | Serine protease hepsin | Homo sapiens | 1 | 1 |
| NPT5085 | Cathepsin H | Homo sapiens | 3 | 5 |
| NPT5080 | Matriptase | Homo sapiens | 1 | 2 |
| NPT1644 | Trypsin | Homo sapiens | 22 | 31 |
| NPT4576 | Glutamate carboxypeptidase II | Homo sapiens | 4 | 4 |
| NPT620 | Subtilisin/kexin type 7 | Homo sapiens | 6 | 15 |
| NPT6608 | Caspase-5 | Homo sapiens | 2 | 3 |
| NPT1090 | Matrix metalloproteinase 13 | Homo sapiens | 15 | 24 |
| NPT1257 | Sentrin-specific protease 6 | Homo sapiens | 4 | 4 |
| NPT1256 | Sentrin-specific protease 7 | Homo sapiens | 4 | 4 |
| NPT1255 | Sentrin-specific protease 8 | Homo sapiens | 7 | 12 |
| NPT1253 | Calpain 2 | Sus scrofa | 2 | 2 |
| NPT6464 | Caspase-4 | Mus musculus | 1 | 2 |
| NPT5013 | Chymase | Homo sapiens | 7 | 11 |
| NPT6325 | Matrix metalloproteinase 10 | Homo sapiens | 2 | 3 |
| NPT4744 | M17 leucyl aminopeptidase | Plasmodium falciparum 3D7 | 3 | 7 |
| NPT740 | Beta-secretase 1 | Homo sapiens | 142 | 226 |
| NPT6616 | Tissue-type plasminogen activator | Homo sapiens | 1 | 2 |
| NPT6500 | Kallikrein 1 | Homo sapiens | 1 | 2 |
| NPT6294 | Tryptase gamma | Homo sapiens | 2 | 4 |
| NPT6299 | ADAM10 | Homo sapiens | 4 | 6 |
| NPT1089 | Matrix metalloproteinase 12 | Homo sapiens | 12 | 23 |
| NPT6470 | Caspase-14 | Homo sapiens | 2 | 3 |
| NPT6430 | Caspase-10 | Homo sapiens | 2 | 3 |
| NPT2993 | Protein BAT5 | Homo sapiens | 1 | 1 |
| NPT2992 | Tripeptidyl-peptidase 2 | Mus musculus | 1 | 1 |
| NPT1474 | ATP-dependent Clp protease proteolytic subunit | Bacillus subtilis (strain 168) | 42 | 43 |
| NPT4197 | Coagulation factor XI | Homo sapiens | 10 | 12 |
| NPT2977 | Thermolysin | Bacillus thermoproteolyticus | 3 | 6 |
| NPT791 | Cruzipain | Trypanosoma cruzi | 174 | 260 |
| NPT4627 | 26S proteasome non-ATPase regulatory subunit 14 | Homo sapiens | 1 | 1 |
| NPT863 | Trypsin | Sus scrofa | 18 | 20 |
| NPT867 | Caspase-6 | Homo sapiens | 14 | 15 |
| NPT2658 | Snake venom metalloproteinase Bap1 | Bothrops asper | 1 | 1 |
| NPT2659 | Ubiquitin carboxyl-terminal hydrolase 5 | Homo sapiens | 1 | 3 |
| NPT6400 | Carboxypeptidase B2 isoform A | Homo sapiens | 3 | 3 |
| NPT1187 | Proteasome Macropain subunit MB1 | Homo sapiens | 8 | 14 |
| NPT1186 | Proteasome Macropain subunit | Homo sapiens | 2 | 3 |
| NPT1185 | Proteasome component C5 | Homo sapiens | 2 | 3 |
| NPT3769 | Elastase 2A | Sus scrofa | 6 | 6 |
| NPT5212 | Sentrin-specific protease 1 | Homo sapiens | 3 | 5 |
| NPT3909 | Beta-secretase 1 | Mus musculus | 1 | 1 |
| NPT3903 | Endoplasmic reticulum aminopeptidase 2 | Homo sapiens | 1 | 1 |
| NPT3904 | Endoplasmic reticulum aminopeptidase 1 | Homo sapiens | 5 | 5 |
| NPT5920 | Bacterial leucyl aminopeptidase | Vibrio proteolyticus | 2 | 2 |
| NPT5923 | Aminopeptidase N | Rattus norvegicus | 1 | 1 |
| NPT2988 | Protein BAT5 | Mus musculus | 1 | 1 |
| NPT5922 | Aminopeptidase B | Mus musculus | 2 | 2 |
| NPT6277 | Botulinum neurotoxin type F | Clostridium botulinum | 1 | 1 |
| NPT4104 | Caspase-2 | Homo sapiens | 3 | 4 |
| NPT5927 | Aminopeptidase B | Homo sapiens | 1 | 1 |
| NPT279 | Leukocyte elastase | Homo sapiens | 34 | 85 |
| NPT278 | Cathepsin G | Homo sapiens | 11 | 12 |
| NPT277 | Caspase-1 | Homo sapiens | 79 | 99 |
| NPT4149 | Gamma-secretase | Homo sapiens | 3 | 5 |
| NPT4413 | M18 aspartyl aminopeptidase | Plasmodium falciparum 3D7 | 6 | 6 |
| NPT3595 | Cathepsin K | Homo sapiens | 13 | 16 |
| NPT3579 | Calpain 1 | Homo sapiens | 13 | 16 |
| NPT6416 | Dipeptidyl peptidase VIII | Homo sapiens | 2 | 3 |
| NPT6510 | Cathepsin E | Homo sapiens | 6 | 13 |
| NPT6512 | Carboxypeptidase N, catalytic subunit | Homo sapiens | 2 | 2 |
| NPT6507 | Carboxypeptidase B | Homo sapiens | 1 | 1 |
| NPT2553 | Aminopeptidase N | Homo sapiens | 6 | 23 |