NPASS Natural Product

Natural Product: NPC330326

Natural Product ID:	NPC330326
Common Name:	Isoniazid
IUPAC Name:	pyridine-4-carbohydrazide
Synonyms:	Dow-Isoniazid; Hyzyd; INH; Isoniazid; Isonicotinylhydrazine; Laniazid; Nicotibine; Nydrazid; Rimifon; Stanozide
Molecular Formula:	C6H7N3O
Standard InCHIKey:	QRXWMOHMRWLFEY-UHFFFAOYSA-N
Standard InCHI:	InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
Canonical SMILES:	NNC(=O)c1ccncc1
First Find Year:
Max Developmental Stage:
Synthetic Gene Cluster:	;

Species Source

Organism ID	Organism Name	Taxonomy Level	Family	SuperKingdom	Isolation Part	Collection Location	Collection Time	Reference
NPO6895	Elateriospermum tapos	Species	Euphorbiaceae	Eukaryota	leaves and stem	Nakorn Si Thammarat Province, Thailand	2004-MAR	PMID[18179177]
NPO20954	Haloxylon salicornicum	Species	Chenopodiaceae	Eukaryota	Whole Plants	Cholistan desert near district Bahawalpur (Punjab), Pakistan	2003-OCT	PMID[20542692]
NPO13391	Streptomyces hygroscopicus	Species	Streptomycetaceae	Bacteria				PMID[24224794]

Biological Activity

Activity Type	# Activity
AC50	5
EC50	4
GI50	6
IC50	131
Ki	7
LD50	8
MIC	1327
Others	447
Potency	44

Activity Type	# Activity
Cell Line	97
Individual Protein	52
Organism	1744
Others	74
Tissue	4
Uncleic Acid	8

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	6631435
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	220	nM	10869194
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	100	%	12880316
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.02	ug/ml	15387639
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC	=	0.4	ug/ml	19386499
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC	=	0.06	ug/ml	19850474
NPT32	Organism	Mus musculus	Mus musculus	Survival	=	100	%	PubChem BioAssay data set
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC95	=	0.4	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	500	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	360	nM	PubChem BioAssay data set
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	10.1007/s00044-004-0032-8
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4	ug/ml	24440480
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC50	=	465	nM	23691978
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	=	1300	nM	24128145
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC50	>	100000	nM	24128145
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1.5	ug/ml	23734701
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	=	200	nM	23734701
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	>	100000	nM	18412396
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	23734701
NPT2	Others	Unspecified		Potency		10903.9	nM	9677274
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	400	nM	18458131
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>=	2	ug/ml	18458131
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100000	ug/ml	18458131
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	<	20	nM	1791472
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	<	160	nM	1791472
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	29190	nM	9461658
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	720	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency		21131.7	nM	PubChem BioAssay data set
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	1	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.2	ug/ml	22934600
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	660	nM	26341134
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	18900	nM	22545792
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	240	nM	22545792
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12.5	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	21982797
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1900000	nM	21982797
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.06	ug/ml	12880316
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Ratio	=	1		10096858
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	310	nM	22168134
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1	ug/ml	8277313
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	<=	400	nM	8277313
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	25	ug/ml	20329739
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	11170665
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	12.5	ug/ml	14738389
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	360	nM	PubChem BioAssay data set
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	45570	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	256	ug/ml	15270571
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	660	nM	7908950
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC95	=	0.1	ug/ml	7908950
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2	ug/ml	23215246
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	18232640
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	7250	nM	19113967
NPT2	Others	Unspecified		MIC	=	1.56	ug/ml	9917285
NPT2739	Individual Protein	Tyrosinase	Mus musculus	Inhibition	=	100	%	15844940
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	1	ug/ml	12444683
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	360	nM	15270567
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.36	ug/ml	26636180
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	90940	nM	26636180
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	Inhibition	=	100	%	10346965
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	8000	nM	10346965
NPT189	Cell Line	Vero	Chlorocebus aethiops	Survival	=	100	%	20329738
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	<	0.2	ug/ml	17877337
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	146	nM	9036182
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	64	ug/ml	24328283
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.025	ug/ml	11421731
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.08	ug/ml	25798528
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.19	ug/ml	25798528
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	25798528
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	25798528
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	25798528
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	>	128000	nM	25798528
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	60	nM	25782063
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	21625478
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	360	nM	7673933
NPT2	Others	Unspecified		Potency		21947.4	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	GI	=	94.2	%	20028029
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.1	ug/ml	12662101
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	17253840
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	200	nM	17253840
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	1433197
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1000	nM	14592480
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	98.42	%	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	DrugMatrix in vitro pharmacology data
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	45570	nM	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12.5	ug/ml	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	7910522
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.02	ug/ml	21452899
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	DrugMatrix in vivo data: Pathology
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.06	ug/ml	DrugMatrix in vivo data: Pathology
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.03	ug/ml	DrugMatrix in vivo data: Pathology
NPT1177	Organism	Mycobacterium phlei	Mycobacterium phlei	MIC	=	16	ug/ml	DrugMatrix in vivo data: Biochemistry
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	DrugMatrix in vivo data: Hematology
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	25993619
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1400	nM	26383126
NPT1118	Organism	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC	>	100	ug/ml	19105653
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	21684166
NPT109	Individual Protein	Cytochrome P450 3A4	Homo sapiens	Ki	=	36000	nM	19877653
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	19743809
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	<	1	ug/ml	20149652
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	20038159
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	0.06	ug/ml	17269824
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	=	128000	nM	19743809
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	19243951
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	19243951
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	14600	nM	19243951
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	24920381
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.1	ug/ml	26186257
NPT5766	Organism	Mycobacterium microti	Mycobacterium microti	MIC	=	22820	nM	15270579
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	IZ	=	29	mm	17190458
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	7	ug/ml	17190458
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	170	nM	9868148
NPT6	Organism	Plasmodium falciparum	Plasmodium falciparum	IC50	=	1200000	nM	19715320
NPT6	Organism	Plasmodium falciparum	Plasmodium falciparum	IC50	=	1800000	nM	19715320
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	200	nM	1602301
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.025	ug/ml	12828469
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	IC50	>	100	ug/ml	12828469
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	22409377
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	310	nM	23558238
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	25978520
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.023	ug/ml	12502310
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	GI50	=	41630	nM	25666824
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	24972328
NPT564	Organism	Listeria monocytogenes	Listeria monocytogenes	MIC	>	100	ug/ml	11374975
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	11000	nM	25734623
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	25734623
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16	ug/ml	17067146
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	500	nM	18217716
NPT2906	Organism	Mycobacterium ulcerans	Mycobacterium ulcerans	MIC	>	40	ug/ml	23819871
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.32	ug/ml	1517739
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	25667960
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	290	nM	18314958
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC	=	467000	nM	12027740
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC80	=	617	nM	25554367
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	32	ug/ml	23327668
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	64	ug/ml	23327668
NPT4071	Organism	Mycobacterium gordonae	Mycobacterium gordonae	MIC	=	32	ug/ml	23327668
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC	=	16	ug/ml	23327668
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	17552563
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	128000	nM	19161316
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	128000	nM	19161316
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	PubChem BioAssay data set
NPT2	Others	Unspecified		Survival	=	103	%	11141106
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	729100	nM	22276742
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC	>	100	ug/ml	19928832
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	19928832
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	100	ug/ml	19928832
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	18177008
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	23691978
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	72.7	%	23190013
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	78.5	%	23190013
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	1	ug/ml	10869208
NPT172	Organism	Proteus mirabilis	Proteus mirabilis	MIC	=	200	ug/ml	PubChem BioAssay data set
NPT6410	Organism	Arthrobacter sp.	Arthrobacter sp.	MIC	=	150	ug/ml	PubChem BioAssay data set
NPT3497	Organism	Klebsiella sp.	Klebsiella sp.	MIC	=	250	ug/ml	PubChem BioAssay data set
NPT1247	Organism	Shigella sp.	Shigella sp.	MIC	=	300	ug/ml	PubChem BioAssay data set
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	=	2520	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	14600	nM	15104514
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.02	ug/ml	8254353
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	730	nM	12027740
NPT81	Cell Line	A549	Homo sapiens	Activity	=	3091	ug/ml	19916528
NPT1970	Cell Line	THP-1	Homo sapiens	Activity	=	2145	ug/ml	19916528
NPT2	Others	Unspecified		Ratio	=	53613		14987072
NPT171	Cell Line	MRC5	Homo sapiens	Activity	=	293	ug/ml	14987072
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	1	ug/ml	16562839
NPT5246	Organism	Mycobacterium aurum	Mycobacterium aurum	MIC	=	2	ug/ml	16562839
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	GI	=	99.3	%	23586849
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	11520220
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	21401023
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	25	ug/ml	23734721
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	2.5	ug/ml	20073490
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	20038128
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	20039640
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	93	%	16562846
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC50	=	180	nM	11960501
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC90	=	11.78	ug/ml	20405845
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	>	95	%	20092289
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	8229009
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12.5	ug/ml	14736236
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1500	nM	22475926
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	IC50	=	0.0012	ug/ml	18298075
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	18298075
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	18000	nM	18298075
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC99	=	0.78	nM	19969457
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	910	nM	9051909
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Ratio IC50	=	1		20521771
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	12662096
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	91140	nM	1360492
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	217	nM	18053715
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	8000	nM	24273638
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	24273638
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	24273638
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.8	nM	24273638
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.75	ug/ml	11908990
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	25066952
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	450	nM	25066952
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	250	nM	12088423
NPT109	Individual Protein	Cytochrome P450 3A4	Homo sapiens	AC50	=	3981.07	nM	21683602
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.06	ug/ml	10.1007/s00044-013-0466-y
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC50	=	0.0019	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	97.7	%	17850214
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.02	ug/ml	PubChem BioAssay data set
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC	>	400	ug/ml	PubChem BioAssay data set
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	IC50	=	0.63	ug/ml	PubChem BioAssay data set
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	IC50	>	4	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	>	128000	nM	PubChem BioAssay data set
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	IC50	=	0.69	ug/ml	21345685
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	20014752
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	PubChem BioAssay data set
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	12.5	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1.1	ug/ml	PubChem BioAssay data set
NPT1829	Organism	Mycobacterium xenopi	Mycobacterium xenopi	MIC	=	12.5	ug/ml	PubChem BioAssay data set
NPT2	Others	Unspecified		IC50	=	0.0023	ug/ml	22831798
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	23398362
NPT65	Cell Line	HepG2	Homo sapiens	Activity	=	10	%	23398362
NPT2	Others	Unspecified		AC50		3162.3	nM	23398362
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	100	%	23398362
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	=	6.25	ug/ml	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	100	ug/ml	23398362
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	1.56	ug/ml	23398362
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	14600	nM	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	>	128	ug/ml	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	370	nM	23398362
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	<	200	nM	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	730	nM	23791078
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	11370	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	25	ug/ml	PubChem BioAssay data set
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	>	0.5	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.025	ug/ml	PubChem BioAssay data set
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	>	455800	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	>	2.19	ug/ml	15689169
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC99	=	0.18	nM	21435874
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	<	6.25	ug/ml	26056748
NPT3473	Organism	Mycobacterium vaccae	Mycobacterium vaccae	MIC	=	182300	nM	22642560
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	30	nM	26073007
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC	>	8000	nM	24216090
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1000	nM	24216090
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	58380	nM	11520227
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	22934671
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	45570	nM	22934671
NPT110	Individual Protein	Cytochrome P450 2D6	Homo sapiens	Potency	=	12589.3	nM	15497938
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	>	455730	nM	8496705
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	IC50	=	9800	nM	23303337
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	23303337
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	20363129
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	8000	nM	19928902
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	700	nM	19928902
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.06	ug/ml	12398547
NPT6551	Individual Protein	Dihydrofolate reductase	Mycobacterium tuberculosis	Ki	=	1	nM	18835171
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Ratio	=	20		18835171
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.094	ug/ml	24893224
NPT2	Others	Unspecified		Potency		19952.6	nM	24893224
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.025	ug/ml	24893224
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12.5	ug/ml	24893224
NPT32	Organism	Mus musculus	Mus musculus	Inhibition	=	45.9	%	24893224
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	740	nM	24033131
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	30	nM	24033131
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	9.77	%	22197393
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.2	ug/ml	22197393
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	>	16	ug/ml	22197393
NPT2	Others	Unspecified		IC50	>	100	ug/ml	22197393
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	23102654
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	250000	nM	17067152
NPT48	Individual Protein	Lysine-specific demethylase 4D-like	Homo sapiens	Potency	=	35481.3	nM	12398531
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1.45	nM	18068371
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	100	ug/ml	20801038
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.098	ug/ml	23806110
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	50	ug/ml	21640594
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.0156	ug/ml	26132528
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	730	nM	11754602
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	4	ug/ml	15165138
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	560	nM	21696954
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	7908950
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.8	nM	22329646
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	19729316
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>=	2	ug/ml	18597527
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>=	2	ug/ml	3210015
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	10425118
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	290	nM	7964780
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC	>	100	ug/ml	14695794
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.025	ug/ml	8691208
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	730	nM	12027740
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC50	=	130	nM	18412396
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.025	ug/ml	10075765
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC50	<	100	nM	23210623
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	23376010
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	25	ug/ml	23301897
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	2.5	ug/ml	23301897
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	2.04	nM	26147490
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	25	ug/ml	10869203
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC90	=	0.075	ug/ml	18636777
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	625	nM	17269824
NPT5832	Organism	Mycobacterium terrae	Mycobacterium terrae	MIC	=	730	nM	24328269
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.39	nM	23368966
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	23910596
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	450	nM	15165160
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	19902967
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	18053715
NPT927	Cell Line	PBMC	Homo sapiens	Activity	=	12.4	%	11929285
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.75	ug/ml	10924160
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	250000	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	16643044
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.1	ug/ml	8133298
NPT5548	Organism	Mycobacterium avium subsp. paratuberculosis	Mycobacterium avium subsp. paratuberculosis	MIC	=	990	nM	23316950
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC	=	80	nM	23316950
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.05	ug/ml	15267244
NPT2	Others	Unspecified		IC50	>	400000	nM	26000707
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2000	nM	20451377
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.5	ug/ml	22583079
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC95	=	0.25	ug/ml	19185486
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	19185486
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	16	ug/ml	19185486
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	19185486
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	19185486
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC90	=	0.125	ug/ml	19185486
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1	ug/ml	17190456
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.4	ug/ml	12825928
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	17542572
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	23164712
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	=	60	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	200	nM	PubChem BioAssay data set
NPT4073	Organism	Mycobacterium	Mycobacterium	MIC50	=	1400	nM	PubChem BioAssay data set
NPT4073	Organism	Mycobacterium	Mycobacterium	MIC90	=	4700	nM	PubChem BioAssay data set
NPT25	Cell Line	MT4	Homo sapiens	CC50	>	100000	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	=	90	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	9800	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.05	ug/ml	PubChem BioAssay data set
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC50	=	1800	nM	PubChem BioAssay data set
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC90	=	6700	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	200	nM	24195447
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	16643039
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	94	%	26317881
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	93.9	%	26317881
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	92.9	%	26317881
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	26317881
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	25419864
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	25356913
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	17315963
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	24128115
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.02	ug/ml	22647719
NPT2	Others	Unspecified		Inhibition	=	0	%	17461599
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	500	nM	20346658
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	200	nM	19265396
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	2374149
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1800	nM	12762807
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	=	39800	nM	12762807
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	18271552
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	9784156
NPT2	Others	Unspecified		CC50	=	1470000	nM	19674906
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC50	=	0.0013	ug/ml	20726569
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	116000	nM	22705001
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.36	ug/ml	24079846
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	24079846
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	<	0.02	ug/ml	24079846
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	15787438
NPT2	Others	Unspecified		Potency		55129.3	nM	23859780
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC50	=	0.0014	ug/ml	16038548
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	6.25	ug/ml	22264149
NPT2	Others	Unspecified		Potency		28727.7	nM	21954912
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	220	nM	15332854
NPT2906	Organism	Mycobacterium ulcerans	Mycobacterium ulcerans	MIC	>	40	ug/ml	20035556
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	11170665
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.05	ug/ml	23611151
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	8	ug/ml	15568767
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	21146414
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	21044847
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.04	ug/ml	21044847
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	<=	500	nM	12444683
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	3.38	log10CFU	19754130
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	2.59	log10CFU	19754130
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	1.22	log10CFU	19670875
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	2.66	log10CFU	23067550
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	26147490
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	15745799
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	6.25	ug/ml	17937983
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100	ug/ml	17937983
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	0.5	ug/ml	17438054
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	80.6	%	17438054
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	83.1	%	17438054
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	0.04	ug/ml	18678487
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC	=	467000	nM	17876006
NPT1829	Organism	Mycobacterium xenopi	Mycobacterium xenopi	MIC	=	12.5	ug/ml	9392889
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	=	12.5	ug/ml	9392889
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.05	ug/ml	17132069
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	16724857
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	16038559
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	100	%	19093848
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	89.65	%	19757815
NPT189	Cell Line	Vero	Chlorocebus aethiops	Survival	=	100	%	20000577
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	20056418
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	450000	nM	19663417
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	0.091	ug/ml	19822701
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	62.5	ug/ml	18505852
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	86.4	%	21041091
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	88.8	%	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	20713679
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC	=	0.1	ug/ml	21334900
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	21376591
NPT32	Organism	Mus musculus	Mus musculus	Survival	=	100	%	21737274
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	500	nM	21764184
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	21776985
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.4	ug/ml	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	360	nM	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	910	nM	22361273
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	0.005	ug/ml	22365879
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	1.5	ug/ml	23137434
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	Activity	=	36	%	23137434
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	100	ug/ml	10.1007/s00044-011-9662-9
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.04	ug/ml	10.1007/s00044-010-9405-3
NPT2	Others	Unspecified		MIC	=	0.04	ug/ml	10.1007/s00044-010-9405-3
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	50	ug/ml	10.1007/s00044-010-9405-3
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	3.13	ug/ml	10.1007/s00044-010-9405-3
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.04	ug/ml	10.1007/s00044-013-0472-0
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	32	ug/ml	10.1007/s00044-012-0458-3
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	29190	nM	23910985
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	23850103
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	1	ug/ml	Open TG-GATES in vivo data: Biochemistry
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	=	8	ug/ml	Open TG-GATES in vivo data: Biochemistry
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	Open TG-GATES in vivo data: Biochemistry
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	Open TG-GATES in vivo data: Biochemistry
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	Open TG-GATES in vivo data: Biochemistry
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	6.25	ug/ml	Open TG-GATES in vivo data: Biochemistry
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	Open TG-GATES in vivo data: Biochemistry
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	1000	ug/ml	Open TG-GATES in vivo data: Biochemistry
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1100	nM	Open TG-GATES in vivo data: Biochemistry
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC50	<	1	ug/ml	Open TG-GATES in vivo data: Hematology
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2.7	ug/ml	Open TG-GATES in vivo data: Hematology
NPT2	Others	Unspecified		MIC50	<	100	nM	Open TG-GATES in vivo data: Hematology
NPT2	Others	Unspecified		MIC	=	3860	nM	Open TG-GATES in vivo data: Hematology
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	Open TG-GATES in vivo data: Hematology
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	Open TG-GATES in vivo data: Hematology
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	730	nM	Open TG-GATES in vivo data: Pathology
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.015	ug/ml	Open TG-GATES in vivo data: Pathology
NPT32	Organism	Mus musculus	Mus musculus	LD50	=	151	mg/kg	Open TG-GATES in vivo data: Organ Weight
NPT32	Organism	Mus musculus	Mus musculus	LD50	=	133	mg/kg	Open TG-GATES in vivo data: Organ Weight
NPT2	Others	Unspecified		IC90	=	0.045	ug/ml	Open TG-GATES in vivo data: Organ Weight
NPT5	Individual Protein	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Homo sapiens	Potency		22387.2	nM	Open TG-GATES in vivo data: Organ Weight
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	450	nM	DrugMatrix in vivo data: Pathology
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	DrugMatrix in vivo data: Pathology
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4.7	ug/ml	DrugMatrix in vivo data: Pathology
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	DrugMatrix in vivo data: Biochemistry
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	FC	=	257.08		DrugMatrix in vivo data: Biochemistry
NPT2	Others	Unspecified		MIC	=	3.13	ug/ml	24224794
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.36	ug/ml	24361479
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	24369840
NPT2739	Individual Protein	Tyrosinase	Mus musculus	Inhibition	=	104	%	24369840
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	24582981
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	8000	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	85.4	%	24852277
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	96.1	%	24852277
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	16	ug/ml	24927053
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.025	ug/ml	24967731
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	24953953
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.04	ug/ml	25129171
NPT2	Others	Unspecified		Inhibition	>	95	%	25828928
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	10.1039/C5MD00178A
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	26642768
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1300	nM	26900657
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	26988804
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	21980963
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.13	nM	21980963
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	200	nM	21980963
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	0.1	ug/ml	21980963
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	11230	nM	4851320
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	27025343
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	26907951
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	17691763
NPT189	Cell Line	Vero	Chlorocebus aethiops	Survival	=	100	%	17958342
NPT48	Individual Protein	Lysine-specific demethylase 4D-like	Homo sapiens	Potency	=	35481.3	nM	17904843
NPT713	Individual Protein	Bile salt export pump	Homo sapiens	IC50	>	1000000	nM	19093884
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	18672316
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	0.037	ug/ml	18672316
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.2	ug/ml	19084294
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	455800	nM	20017493
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	64	ug/ml	19520580
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC	=	16	ug/ml	20143778
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	>	512000	nM	20055418
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	20669972
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	20669972
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	58300	nM	16921367
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	>=	99	%	16921367
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	20947351
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	100	%	21476600
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	21080647
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	360	nM	21080647
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	100	%	21742496
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	7000000	nM	21215647
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	21634430
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	21548582
NPT317	Uncleic Acid	Nucleic Acid		Activity	=	8		21955276
NPT317	Uncleic Acid	Nucleic Acid		Activity	=	51		PubChem BioAssay data set
NPT317	Uncleic Acid	Nucleic Acid		Activity	=	50.8	%	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	21984958
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	22260166
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	32	ug/ml	22435669
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	22435669
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	64	ug/ml	22435669
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC	=	16	ug/ml	22435669
NPT4071	Organism	Mycobacterium gordonae	Mycobacterium gordonae	MIC	=	32	ug/ml	22435669
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	24900500
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC	=	0.125	ug/ml	10.1007/s00044-011-9623-3
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.03	ug/ml	23252603
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC90	=	200	nM	23252603
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	8	ug/ml	23252603
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	23368884
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	10.6019/CHEMBL1201861
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	10.6019/CHEMBL1201861
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	10.6019/CHEMBL1201861
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	>	467000	nM	10.6019/CHEMBL1201861
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	50	nM	10.6019/CHEMBL1201861
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	0.1	ug/ml	10.6019/CHEMBL1201861
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	312	nM	10.6019/CHEMBL1201861
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	10.6019/CHEMBL1201861
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	>	100	ug/ml	10.6019/CHEMBL1201861
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	10.6019/CHEMBL1201861
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	10.6019/CHEMBL1201861
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	3000	nM	10.6019/CHEMBL1201861
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	3200	nM	10.6019/CHEMBL1201861
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	<	200	nM	10.6019/CHEMBL1201861
NPT2906	Organism	Mycobacterium ulcerans	Mycobacterium ulcerans	MIC	>	40	ug/ml	10.6019/CHEMBL1201861
NPT213	Individual Protein	Cytochrome P450 2C19	Homo sapiens	Ratio IC50	>	5		23792316
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	2.04	nM	24015327
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	91000	nM	24164245
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	24345446
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2000	nM	24613456
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	24766560
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	<	0.2	ug/ml	25563890
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC	=	0.03	ug/ml	25815139
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	2.5	ug/ml	25815139
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1.5	ug/ml	25974739
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	>	8000	nM	26149591
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	430	nM	26149591
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.1	ug/ml	26331334
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.2	ug/ml	26613635
NPT621	Tissue	Plasma	Homo sapiens	Ratio	=	1.35		10.1039/C5MD00247H
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.65	ug/ml	26814680
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	0.2	ug/ml	26443078
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.03	ug/ml	26443078
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	>	500000	nM	26443078
NPT927	Cell Line	PBMC	Homo sapiens	IC50	=	169	ug/ml	26890116
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	10.1039/C5MD00451A
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	26937828
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2000	nM	26937828
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	26937828
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	27177826
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	27177826
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	27177826
NPT927	Cell Line	PBMC	Homo sapiens	IC50	>	100	ug/ml	27177826
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	455800	nM	27177826
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	27177826
NPT927	Cell Line	PBMC	Homo sapiens	IC50	=	87.08	ug/ml	27177826
NPT927	Cell Line	PBMC	Homo sapiens	Survival	>	95	%	27177826
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	4.71		27177826
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	370	nM	27142751
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	455800	nM	20624681
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	51.39	%	20337496
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	100000	nM	16038541
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	16038541
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	180	nM	8450319
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	8450319
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	23210623
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100	ug/ml	23266177
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.23	ug/ml	8496706
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	8496706
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.75	ug/ml	19711986
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	11400	nM	7769398
NPT1177	Organism	Mycobacterium phlei	Mycobacterium phlei	MIC	=	91150	nM	22551062
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MBC	=	1.75	nM	19928902
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	880	nM	20303767
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	730	nM	16989538
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	12.5	ug/ml	23465614
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	6.3	ug/ml	23465614
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	23394284
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1.56	ug/ml	19761234
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	4	RLU	22409377
NPT2906	Organism	Mycobacterium ulcerans	Mycobacterium ulcerans	MIC	>	40	ug/ml	21376588
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	=	12.5	ug/ml	24720452
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI50	=	0.01	ug/ml	24720452
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	100	%	19674906
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	450	nM	16933872
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	84	%	16933872
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	8000	nM	17190448
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	8699183
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1000	nM	11975502
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	0.5	ug/ml	15620238
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI50	=	10	nM	12350153
NPT2	Others	Unspecified		Potency		13333.2	nM	12350153
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100	ug/ml	12350153
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.03	ug/ml	12502331
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	0.75	ug/ml	15911254
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	95	%	8904842
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	32000	nM	17994701
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	32000	nM	18829331
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	437	nM	17343407
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	17279798
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	25537529
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	290	nM	25537529
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC50	=	0.0025	ug/ml	25819096
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	100	%	25819096
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	15974572
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	<=	400	nM	9917312
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	91000	nM	21524582
NPT633	Organism	Leishmania donovani	Leishmania donovani	IC50	>	218750	nM	21524582
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	Ratio	=	2		PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	20.9	%	20598551
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	17095216
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	92	%	23501116
NPT485	Organism	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	MIC	=	0.1	ug/ml	10346946
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.025	ug/ml	23511018
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	60	nM	2045815
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	660	nM	22119124
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	22119124
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.03	ug/ml	20627737
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.2	ug/ml	19013823
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	800	nM	25556102
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	128000	nM	9358645
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	220	nM	9358645
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	91140	nM	22705001
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Ratio	=	1		22705001
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC50	=	30	nM	26331986
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	>	455730	nM	21718054
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	330	nM	15787431
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	250	nM	26186257
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	116800	nM	18590312
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.24	ug/ml	16643051
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	25927586
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	45570	nM	4020828
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.06	ug/ml	12699389
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	660	nM	18164197
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	GI50	=	7.94	ug/ml	7853002
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	450000	nM	16180824
NPT4325	Individual Protein	Pantothenate synthetase	Mycobacterium tuberculosis	Inhibition	=	0	%	19576785
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	467000	nM	19576785
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.08	ug/ml	20112996
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	128	ug/ml	18426954
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.65	ug/ml	21144756
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	20014752
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	>	100	ug/ml	20190787
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	0.03	ug/ml	21456549
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC	=	7300	nM	21604746
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	200	ug/ml	21663319
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	10000	nM	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	0.0625	ug/ml	DrugMatrix in vitro pharmacology data
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	Activity	=	-6	%	DrugMatrix in vitro pharmacology data
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	25	ug/ml	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	21920638
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	0.5	ug/ml	22530779
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	8960059
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>=	2	ug/ml	10.1007/s00044-011-9832-9
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	360	nM	10.1007/s00044-012-0142-7
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	98.42	%	10.6019/CHEMBL1201861
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	10.6019/CHEMBL1201861
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	10.6019/CHEMBL1201861
NPT2	Others	Unspecified		MIC	=	760	nM	10.6019/CHEMBL1201861
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	11580	nM	10.6019/CHEMBL1201861
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	10.6019/CHEMBL1201861
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	>	364670	nM	10.6019/CHEMBL1201861
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	45570	nM	10.6019/CHEMBL1201861
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	8000	nM	23822556
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC99	=	4	ug/ml	23822556
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	24223237
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	DrugMatrix in vivo data: Pathology
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	DrugMatrix in vivo data: Pathology
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.125	ug/ml	DrugMatrix in vivo data: Pathology
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	DrugMatrix in vivo data: Pathology
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	12.07	ug/ml	DrugMatrix in vivo data: Pathology
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	EC90	=	0.03	ug/ml	DrugMatrix in vivo data: Pathology
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC	>	400	ug/ml	DrugMatrix in vivo data: Biochemistry
NPT712	Individual Protein	Bile salt export pump	Rattus norvegicus	IC50	>	1000000	nM	DrugMatrix in vivo data: Biochemistry
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	0.05	ug/ml	DrugMatrix in vivo data: Biochemistry
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	15646539
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	=	100	nM	25025991
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	>	100000	nM	25025991
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	12713411
NPT180	Cell Line	HCT-8	Homo sapiens	EC50	>	100000	nM	10560746
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC100	=	0.1	ug/ml	11170658
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	360	nM	16078824
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC50	<	1	ug/ml	17521907
NPT4325	Individual Protein	Pantothenate synthetase	Mycobacterium tuberculosis	IC50	>	25000	nM	22738271
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.06	ug/ml	23672690
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.04	ug/ml	23434422
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.5	ug/ml	23434420
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	3.1	ug/ml	23434420
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.075	ug/ml	23434131
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	24625088
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	660	nM	22313254
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.2	ug/ml	23035772
NPT2	Others	Unspecified		Inhibition	=	-39	%	26358281
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	910	nM	22686608
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	15165134
NPT5548	Organism	Mycobacterium avium subsp. paratuberculosis	Mycobacterium avium subsp. paratuberculosis	MIC50	<	100	nM	16933872
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	17994703
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC80	=	449	nM	18329753
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12500	nM	17665953
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	100	ug/ml	25237727
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC	=	116000	nM	26169123
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MBC	=	0.12	ug/ml	26169123
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	0.25	ug/ml	26169123
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	26169123
NPT317	Uncleic Acid	Nucleic Acid		Kb	=	1.6	10'4/M	15620251
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.1	ug/ml	15620251
NPT317	Uncleic Acid	Nucleic Acid		Kb	=	1.42	10'4/M	15620251
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	24033077
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	24033077
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	250000	nM	22642560
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	250000	nM	14738379
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2	ug/ml	19928902
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	20121165
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	15043413
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	85.5	%	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	89.3	%	PubChem BioAssay data set
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	12	ug/ml	18177011
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	=	1459850	nM	PubChem BioAssay data set
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	16872131
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC90	=	290	nM	16180822
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	8000	nM	11325232
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	62.5	ug/ml	14640526
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100	ug/ml	14640526
NPT32	Organism	Mus musculus	Mus musculus	LD50	=	133	mg/kg	9873389
NPT32	Organism	Mus musculus	Mus musculus	LD50	=	151	mg/kg	18341287
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	86.4	%	18341287
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	85.5	%	18341287
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	87.6	%	18341287
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	88	%	18341287
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	88.4	%	17665951
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	89.3	%	17665951
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	96	%	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	0.2	ug/ml	25597007
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC	=	12.5	ug/ml	25970729
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	23441911
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	17595133
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	100	nM	12880316
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.4	ug/ml	25856683
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	23368996
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	15679321
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	76.4	%	24484201
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	600	nM	25707014
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC	=	0.1	ug/ml	22834923
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	60	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	95	%	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.098	ug/ml	PubChem BioAssay data set
NPT2	Others	Unspecified		Inhibition	=	78.5	%	25238443
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	9358638
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.36	ug/ml	12027772
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	12027772
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.041	ug/ml	22758660
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.048	ug/ml	18198839
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1820	nM	18537291
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	370	nM	15214779
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.01	ug/ml	16872140
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	64	ug/ml	17253840
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.4	ug/ml	19191549
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	PubChem BioAssay data set
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	PubChem BioAssay data set
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.6	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99.98	%	14664515
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	22264149
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	8000	nM	22264149
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC100	=	1.25	nM	22264149
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	17.5	ug/ml	11325240
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	220	nM	11325240
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	26024020
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	8	ug/ml	19555123
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	11000	nM	19338315
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	455800	nM	26836364
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4.7	ug/ml	12608857
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.03	ug/ml	12608857
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	16378381
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	18177007
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.1	ug/ml	8158155
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	100	ug/ml	8158155
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	220	nM	PubChem BioAssay data set
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC99	>	50	nM	16441065
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	15104515
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	128000	nM	9868148
NPT2	Others	Unspecified		Potency		1223.4	nM	18507473
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2000	nM	19159272
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	43800	nM	19271717
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12500	nM	15332839
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	0.5	ug/ml	22834923
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	8000	nM	20022253
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	360	nM	20159656
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	90	nM	20159656
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	20159656
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	20056545
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	19072209
NPT612	Individual Protein	Canalicular multispecific organic anion transporter 1	Homo sapiens	Activity	=	96	%	21314138
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	>	455730	nM	19969457
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	16643033
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	840	nM	16499318
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	15974602
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100	ug/ml	26225905
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	13000	nM	26225905
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	7300	nM	14643343
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1170	nM	23301897
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	0	CFU	23301897
NPT2	Others	Unspecified		Activity	=	26	CFU	22409377
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	12	CFU	24326280
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	2292689
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC90	=	0.075	ug/ml	26096681
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC99	=	130	nM	12398543
NPT605	Organism	Homo sapiens	Homo sapiens	Activity	=	0.8	%	10543898
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	19056282
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	200	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	23376010
NPT2	Others	Unspecified		IC50	=	5000	nM	24099304
NPT2	Others	Unspecified		IC50	=	10000	nM	17910513
NPT2	Others	Unspecified		IC50	=	100000	nM	17910513
NPT2	Others	Unspecified		IC50	=	2600	nM	20061160
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	12350171
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	90	%	19928902
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.025	ug/ml	19496609
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	23964644
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	364670	nM	7852999
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	7	nM	12444692
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC50	=	30	nM	19739600
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.03	ug/ml	19739600
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	15497935
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	95	%	18211005
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	32000	nM	15043429
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	10785428
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	12.5	ug/ml	10075754
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.1	ug/ml	26287401
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	45570	nM	22196120
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.04	ug/ml	PubChem BioAssay data set
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	456000	nM	22694318
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	10820113
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	23985009
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	24576210
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	500	nM	23046382
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC99	=	0.18	nM	15050615
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	17929796
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	17929796
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	IC90	<	72900	nM	19459645
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	128000	nM	12747785
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.1	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>=	2	ug/ml	18598080
NPT32	Organism	Mus musculus	Mus musculus	LD50	=	133	mg/kg	PubChem BioAssay data set
NPT32	Organism	Mus musculus	Mus musculus	LD50	=	151	mg/kg	PubChem BioAssay data set
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	130500	nM	17067151
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	16168652
NPT317	Uncleic Acid	Nucleic Acid		Activity	=	77.1	%	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	91000	nM	PubChem BioAssay data set
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	29200	nM	25970561
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.63	ug/ml	15974580
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	128000	nM	25453801
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC50	=	0.0024	ug/ml	26090896
NPT6	Organism	Plasmodium falciparum	Plasmodium falciparum	IC50	=	246460	nM	16137881
NPT580	Organism	Trypanosoma cruzi	Trypanosoma cruzi	IC50	=	382820	nM	16137881
NPT633	Organism	Leishmania donovani	Leishmania donovani	IC50	>	729180	nM	16137881
NPT2	Others	Unspecified		IC50	>	218750	nM	16137881
NPT844	Organism	Trypanosoma brucei rhodesiense	Trypanosoma brucei rhodesiense	IC50	>	729180	nM	15787438
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	455800	nM	2045815
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC90	=	110	nM	19095451
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	11370	nM	15620248
NPT2	Others	Unspecified		Potency		13333.2	nM	15620238
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2000	nM	10650083
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	10650083
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	230	nM	20627740
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2000	nM	20627740
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Activity	=	151.25	U/ml	20593839
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	15.01	%	20627740
NPT2	Others	Unspecified		Ratio	=	660		10869203
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Survival	=	100	%	10866403
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Survival	=	100	%	17157006
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	730	nM	15711537
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1000	nM	15711537
NPT621	Tissue	Plasma	Homo sapiens	Ratio	=	3.22		15711537
NPT5832	Organism	Mycobacterium terrae	Mycobacterium terrae	MIC	=	0.1	ug/ml	15711537
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	2600	nM	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	360	nM	17850214
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	17850214
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC50	=	190	nM	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	6.25	ug/ml	18183025
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	780	nM	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	64000	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	440	nM	PubChem BioAssay data set
NPT65	Cell Line	HepG2	Homo sapiens	IC50	>	250000	nM	22831798
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	22831798
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.1	ug/ml	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1.56	ug/ml	23398362
NPT2	Others	Unspecified		MIC	=	45570	nM	23398362
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	400	nM	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.02	ug/ml	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.5	ug/ml	23398362
NPT153	Individual Protein	Androgen Receptor	Homo sapiens	Potency		23019.6	nM	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Ratio	=	1		12193011
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Inhibition	=	19	%	15270558
NPT2	Others	Unspecified		IC50	=	10000	nM	15270558
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Inhibition	=	22	%	15270558
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	15270558
NPT628	Individual Protein	Cytochrome P450 2C8	Homo sapiens	Ki	=	170000	nM	18177012
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	660	nM	25682561
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	20022253
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	70	nM	20022253
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	17958397
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	11170663
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.125	ug/ml	12141877
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	21421320
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	11380	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	729000	nM	PubChem BioAssay data set
NPT72	Individual Protein	Solute carrier organic anion transporter family member 1B3	Homo sapiens	Inhibition	=	98.94	%	19615900
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC50	=	330	nM	18052327
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	12617583
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC	>	0.5	ug/ml	25237727
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	17.9	%	3443856
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.07	ug/ml	23079524
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	15620264
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	21872367
NPT43	Individual Protein	Tyrosinase	Agaricus bisporus	IC50	>	1000000	nM	12713412
NPT81	Cell Line	A549	Homo sapiens	IC50	>	450000	nM	11429990
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.075	ug/ml	8864235
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	8864235
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	25668638
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	32	ug/ml	12617583
NPT4071	Organism	Mycobacterium gordonae	Mycobacterium gordonae	MIC	=	32	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	24387625
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	12502308
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	19931462
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	95	%	25597012
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	19775092
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	19653640
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	>	128000	nM	20541427
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	19388709
NPT443	Individual Protein	Histone acetyltransferase GCN5	Homo sapiens	Potency		15848.9	nM	20886871
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	14584959
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Ratio	=	100		26295746
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Ratio	=	3.1		26295746
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Ratio	=	6.25		26259802
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	200	ug/ml	26259802
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	95	%	19689125
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.4	ug/ml	25333996
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	14600	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	467100	nM	8691203
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	8000	nM	8691203
NPT2	Others	Unspecified		Ratio	=	128		11325227
NPT2	Others	Unspecified		MIC	=	291800	nM	16643040
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2000	nM	15387645
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	95	%	15387645
NPT81	Cell Line	A549	Homo sapiens	IC50	>	450000	nM	12880316
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	23046382
NPT720	Organism	Enterobacter aerogenes	Enterobacter aerogenes	MIC	>	100	ug/ml	PubChem BioAssay data set
NPT766	Organism	Proteus vulgaris	Proteus vulgaris	MIC	>	100	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1800	nM	24601669
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	8	ug/ml	PubChem BioAssay data set
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.0234	ug/ml	17896816
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.4	nM	2453615
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	9722490
NPT10	Individual Protein	Geminin	Homo sapiens	Potency		794.3	nM	1336040
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	10	ug/ml	10924160
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC	=	16	ug/ml	10924160
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	450000	nM	10924166
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	59.1	%	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	68.7	%	PubChem BioAssay data set
NPT49	Individual Protein	DNA-(apurinic or apyrimidinic site) lyase	Homo sapiens	Potency		1000	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	32	ug/ml	24328302
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	60	nM	24328302
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	24328269
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.125	ug/ml	26707398
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	23273047
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	22963193
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>=	2	ug/ml	22938151
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	98	%	25760525
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	8.5	ug/ml	19904995
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	89.6	%	18582112
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.09	ug/ml	15387645
NPT4325	Individual Protein	Pantothenate synthetase	Mycobacterium tuberculosis	IC50	>	25000	nM	22264170
NPT65	Cell Line	HepG2	Homo sapiens	IC50	>	250000	nM	22264170
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	IC50	=	0.0023	ug/ml	26241103
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	1593279
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	19026551
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	100000	nM	17722904
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	94.7	%	20594622
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	59579931.56	nM	23112103
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	98.99	%	23112103
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	84.37	%	24050653
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	89.6	%	16309323
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	95.85	%	16309323
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	17067147
NPT2	Others	Unspecified		Potency		28727.7	nM	23957453
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Activity	=	1.55	g/dl	PubChem BioAssay data set
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Activity	=	8.31	U/ml	PubChem BioAssay data set
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Activity	=	1.48	g/dl	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	310	nM	PubChem BioAssay data set
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.23	ug/ml	PubChem BioAssay data set
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	25	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	15104487
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.0625	ug/ml	11858756
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	45570	nM	18973387
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4	ug/ml	22880631
NPT2	Others	Unspecified		MIC	=	12.5	ug/ml	22834923
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	8350092
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.094	ug/ml	10869194
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	23806110
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	290	nM	26259802
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	23000	nM	15165148
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	500	nM	15165148
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MBC	=	0.1	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	0.2	ug/ml	PubChem BioAssay data set
NPT580	Organism	Trypanosoma cruzi	Trypanosoma cruzi	IC50	>	150000	nM	19786608
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	185	ug	19188399
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	20843939
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC90	=	0.29	nM	16472241
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	0.05	ug/ml	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.04	ug/ml	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	20	ug/ml	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.0625	ug/ml	DrugMatrix in vitro pharmacology data
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	250000	nM	22480197
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	12.5	ug/ml	15646539
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	50	ug/ml	15646539
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1.56	ug/ml	15646539
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC99	=	1	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	11429258
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	8000	nM	17547458
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	17547458
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	4	ug/ml	11929285
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	11929285
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	16252912
NPT2	Others	Unspecified		Potency		13333.2	nM	3598594
NPT2	Others	Unspecified		Potency		33491.5	nM	26706168
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	>	50	ug/ml	2809606
NPT317	Uncleic Acid	Nucleic Acid		Kb	=	1.6	10'4/M	19874044
NPT317	Uncleic Acid	Nucleic Acid		Kb	=	2.03	10'4/M	19874044
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	99	%	18177008
NPT2	Others	Unspecified		IC50	>	50000	nM	10479316
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	GI	=	0	%	17060532
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	82.3	%	17210772
NPT1177	Organism	Mycobacterium phlei	Mycobacterium phlei	MIC	=	128	ug/ml	17267227
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	0.25	ug/ml	17267227
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	0.25	ug/ml	17267227
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	500000	nM	17502410
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	17698630
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	0.05	ug/ml	19908867
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	360	nM	20070106
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.5	ug/ml	18227183
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	20439614
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	70000	nM	20439614
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	85	%	19075048
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	50	ug/ml	19114678
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	600	nM	19114678
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1.56	ug/ml	19114678
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	19114678
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	19332671
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	310	nM	19738019
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	45570	nM	19738019
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	62.5	ug/ml	20855744
NPT109	Individual Protein	Cytochrome P450 3A4	Homo sapiens	Potency	=	3981.1	nM	20733041
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	29200	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	100	nM	DrugMatrix in vitro pharmacology data
NPT2	Others	Unspecified		IC50	>	100000	nM	DrugMatrix in vitro pharmacology data
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC90	=	0.074	ug/ml	22194678
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.03	ug/ml	10.1007/s00044-007-9020-0
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	730	nM	26264847
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	25	ug/ml	26344590
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	730	nM	10.1016/S0960-894X(97)00178-9
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	92.8	%	7538590
NPT2	Others	Unspecified		Potency		18285.1	nM	17664328
NPT110	Individual Protein	Cytochrome P450 2D6	Homo sapiens	AC50	=	12589.25	nM	17242147
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	230	nM	19228000
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	20117930
NPT2	Others	Unspecified		Ratio	>	20000		19586686
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	20149495
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	18316521
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	100000	nM	20308377
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	20863701
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	15920768
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC100	<=	0.12	ug/ml	21183354
NPT109	Individual Protein	Cytochrome P450 3A4	Homo sapiens	Potency	=	15848.9	nM	20516271
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	=	41	ug/ml	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	=	120	ug/ml	DrugMatrix in vitro pharmacology data
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	DrugMatrix in vitro pharmacology data
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC50	=	0.0025	ug/ml	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	DrugMatrix in vitro pharmacology data
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	22858097
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.034	ug/ml	DrugMatrix in vivo data: Hematology
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC	>	1000000	nM	15646539
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	25600408
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	180	nM	24926807
NPT32	Organism	Mus musculus	Mus musculus	Survival	=	100	%	25847765
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Survival	=	100	%	25946116
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	15711537
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	15711537
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.36	ug/ml	15711537
NPT2	Others	Unspecified		Potency		10193	nM	15711537
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	15711537
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	18393402
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	0.18	ug/ml	19282176
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	IC50	=	1.851	ug/ml	19128055
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	4	ug/ml	19128055
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	19128055
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.8	ug/ml	19128055
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC99	=	45.57	nM	19128055
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4.7	ug/ml	17850214
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.125	ug/ml	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	18183025
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	>	455800	nM	18183025
NPT213	Individual Protein	Cytochrome P450 2C19	Homo sapiens	Ki	=	10000	nM	18183025
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.125	ug/ml	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	19854650
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.02	ug/ml	20361800
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	IC50	=	39000	nM	15958589
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	IC50	=	7800	nM	15958589
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	15958589
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC95	=	4.4	nM	21417417
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100	ug/ml	21417417
NPT2	Others	Unspecified		Potency		190	nM	21080703
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45600	nM	22000924
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.24	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	>	128000	nM	23252711
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	23352483
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	72900	nM	10.6019/CHEMBL1201861
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	0.5	ug/ml	10.6019/CHEMBL1201861
NPT113	Cell Line	RAW264.7	Mus musculus	IC50	>	400	ug/ml	10.6019/CHEMBL1201861
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	357	nM	10.6019/CHEMBL1201861
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC99	=	0.1	ug/ml	10.6019/CHEMBL1201861
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	10.6019/CHEMBL1201861
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	45570	nM	23623491
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	45570	nM	25757603
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	7300	nM	4032421
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	40	ug/ml	4032421
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.125	ug/ml	20485427
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	=	0.125	ug/ml	20485427
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.25	ug/ml	20485427
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.05	ug/ml	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	100000	nM	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	300	nM	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1	ug/ml	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.39	nM	DrugMatrix in vitro pharmacology data
NPT806	Individual Protein	Glutamate decarboxylase 67 kDa isoform	Rattus norvegicus	Inhibition	=	42	%	DrugMatrix in vivo data: Biochemistry
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	DrugMatrix in vivo data: Hematology
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	200	nM	24183741
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100	ug/ml	22393119
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	250000	nM	22393119
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	22393119
NPT71	Cell Line	HEK293	Homo sapiens	LC50	>	200	ug/ml	22393119
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC50	=	12.07	ug/ml	8254344
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	30	nM	23855338
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	200000	nM	26331426
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	15	nM	9917283
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.04	ug/ml	25437304
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	19105653
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	19105653
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	19296616
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.19	ug/ml	19296616
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	19216517
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	19818612
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.031	ug/ml	11473412
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2	ug/ml	10691710
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	730	nM	16872149
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	16	ug/ml	15497934
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	16	ug/ml	15497934
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	16643047
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	=	8	ug/ml	16643047
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IZ	<=	21	mm	20624681
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	15497936
NPT484	Individual Protein	Luciferin 4-monooxygenase	Photinus pyralis	Potency	=	5011.9	nM	15387647
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.02	ug/ml	18826276
NPT109	Individual Protein	Cytochrome P450 3A4	Homo sapiens	Ratio IC50	>	5		21911291
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	64	ug/ml	26420067
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	16933872
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	16933872
NPT2906	Organism	Mycobacterium ulcerans	Mycobacterium ulcerans	MIC	>	40	ug/ml	15332848
NPT175	Organism	Enterococcus faecalis	Enterococcus faecalis	MIC	>	100	ug/ml	15332848
NPT2	Others	Unspecified		Potency		11436.7	nM	18288806
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.5	ug/ml	16038541
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	128000	nM	9917285
NPT1970	Cell Line	THP-1	Homo sapiens	IC50	>	3649000	nM	19391605
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	11000	nM	14640526
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	12502321
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1800	nM	15214779
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>=	2	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC90	=	0.11	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	450	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1	ug/ml	25372480
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	25372480
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	2	ug/ml	18278870
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2	ug/ml	11678653
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	8	ug/ml	11678653
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	3.1	ug/ml	16724853
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.06	ug/ml	16724853
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.125	ug/ml	13678412
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	13678412
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1	ug/ml	22703109
NPT65	Cell Line	HepG2	Homo sapiens	IC50	>	1000000	nM	3806622
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.05	ug/ml	11212121
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	=	62.5	ug/ml	8308864
NPT81	Cell Line	A549	Homo sapiens	IC50	>	450000	nM	18442909
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1.56	ug/ml	18442909
NPT2	Others	Unspecified		IC50	>	656260	nM	18061311
NPT2	Others	Unspecified		IC50	=	602300	nM	18061311
NPT633	Organism	Leishmania donovani	Leishmania donovani	IC50	>	218750	nM	18061311
NPT6	Organism	Plasmodium falciparum	Plasmodium falciparum	IC50	>	36460	nM	19209889
NPT580	Organism	Trypanosoma cruzi	Trypanosoma cruzi	IC50	>	656260	nM	19209889
NPT2	Others	Unspecified		IC50	>	218750	nM	19209889
NPT844	Organism	Trypanosoma brucei rhodesiense	Trypanosoma brucei rhodesiense	IC50	>	656260	nM	19209889
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.05	ug/ml	18590939
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	660	nM	19480409
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	17938185
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.03	ug/ml	17938185
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	>	0.5	ug/ml	17938185
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	18070958
NPT1593	Tissue	Liver	Rattus norvegicus	Activity	=	9.1	nmol	18070958
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	38.48	%	18070958
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	19805556
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.68	ug/ml	19805556
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	19805556
NPT621	Tissue	Plasma	Homo sapiens	Ratio	=	0.22		18411326
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	IC50	=	15000	nM	20100877
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC90	=	210	nM	20100877
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	18694944
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	200	nM	18838581
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2000	nM	18955522
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	6.25	ug/ml	20961670
NPT65	Cell Line	HepG2	Homo sapiens	Activity	=	128.56	%	19015349
NPT65	Cell Line	HepG2	Homo sapiens	Activity	=	91.31	%	19015349
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	0.033	ug/ml	19223619
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.04	ug/ml	19528279
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	6.25	ug/ml	19581457
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	128000	nM	19581457
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	910	nM	19581457
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	19581457
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	19581457
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	19581457
NPT2	Others	Unspecified		Potency		22819.2	nM	20585132
NPT71	Cell Line	HEK293	Homo sapiens	LC50	>	576	ug/ml	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	400	nM	DrugMatrix in vitro pharmacology data
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	Inhibition	=	100	%	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	360	nM	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	37	%	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Ratio	=	1		DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC50	=	540	nM	10.1007/s00044-010-9547-3
NPT1277	Organism	Staphylococcus epidermidis ATCC 12228	Staphylococcus epidermidis ATCC 12228	MIC	>	4	ug/ml	10.1007/s00044-012-0429-8
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC99	=	0.36	nM	23644202
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	810	nM	23644202
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.125	ug/ml	DrugMatrix in vivo data: Biochemistry
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2	ug/ml	DrugMatrix in vivo data: Biochemistry
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	4	ug/ml	DrugMatrix in vivo data: Hematology
NPT628	Individual Protein	Cytochrome P450 2C8	Homo sapiens	Ki	=	374000	nM	24224794
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC	=	12.5	ug/ml	24360560
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	10.6019/CHEMBL3301361
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4	ug/ml	10.6019/CHEMBL3392926
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	18197599
NPT2739	Individual Protein	Tyrosinase	Mus musculus	Inhibition	=	97	%	23317013
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	15568794
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	19425589
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	10	ug/ml	20192239
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	ED99	=	0.95	mg/kg	24099304
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	32	ug/ml	26200396
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	8.56	%	19368377
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.04	ug/ml	8277313
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC50	=	0.0025	ug/ml	24957203
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	23977995
NPT32	Organism	Mus musculus	Mus musculus	LD50	=	100	mg/kg	19848434
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	450000	nM	15217280
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.02	ug/ml	15026054
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	20346682
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	100	%	17547457
NPT2	Others	Unspecified		Potency		21947.4	nM	17291045
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	71.5	%	25286284
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	95	%	23718637
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	455770	nM	12542345
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	21924800
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	21705225
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	600	nM	19496609
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	18942825
NPT4585	Organism	Mycobacterium diernhoferi	Mycobacterium diernhoferi	MIC	=	0.25	ug/ml	15043409
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	0.1	ug/ml	23876104
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Activity	=	40.21	U/ml	19658408
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	32000	nM	17279797
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	FC	=	1.2		12502326
NPT65	Cell Line	HepG2	Homo sapiens	Activity	=	56.13	%	19650652
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.78	nM	22545792
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Ratio	=	400		20045651
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Ratio	=	50		20061160
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Ratio	=	25		20061160
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	14600	nM	18314958
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	14600	nM	22583079
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	EC99	=	0.42	ug/ml	11325222
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	EC90	=	0.03	ug/ml	8946741
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MBC	>	1.6	ug/ml	17512741
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC99	=	45.57	nM	9090874
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	21970540
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	21970540
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	11277768
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	22820	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	95	%	17190469
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	14600	nM	12662097
NPT1177	Organism	Mycobacterium phlei	Mycobacterium phlei	MIC	=	14600	nM	12662097
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	5250	nM	22260257
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	19334707
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	410	nM	17993275
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	300	nM	20232859
NPT6005	Organism	Mycobacterium scrofulaceum	Mycobacterium scrofulaceum	MIC	=	116000	nM	15620248
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	=	6282800	nM	15497938
NPT113	Cell Line	RAW264.7	Mus musculus	GI50	=	3000	ug/ml	10579870
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	900	nM	8691203
NPT2	Others	Unspecified		Ratio	>	1000		25176187
NPT109	Individual Protein	Cytochrome P450 3A4	Homo sapiens	Potency	=	3981.1	nM	21146414
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.0625	ug/ml	7903980
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.3	nM	15679321
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC90	=	290	nM	20405847
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	20405847
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	49.7	%	24412339
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	=	0.25	ug/ml	24412339
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	625	nM	10.1016/S0960-894X(01)81072-6
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	2800	nM	10479316
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	17896816
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	18281952
NPT152	Individual Protein	Nuclear factor erythroid 2-related factor 2	Homo sapiens	Potency		2033.8	nM	23282042
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	12.5	ug/ml	25517209
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	256000	nM	25453801
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	25453801
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	16	ug/ml	20939540
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	=	8	ug/ml	12398531
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC95	=	1.8	nM	23265253
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	660	nM	12662097
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	24949913
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	17125218
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	70000	nM	20806908
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.05	ug/ml	19216517
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	300	ug/ml	2166136
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	9677265
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	455800	nM	15568791
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	>	729100	nM	16792409
NPT208	Individual Protein	Cytochrome P450 1A2	Homo sapiens	Ki	=	56000	nM	18076141
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	23360521
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	16420055
NPT2	Others	Unspecified		AC50		707.9	nM	21625478
NPT2	Others	Unspecified		Potency		3162.3	nM	8289059
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	730	nM	20025236
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	25420212
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	10096871
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	0.045	ug/ml	10843598
NPT2	Others	Unspecified		Potency		23019.6	nM	11908979
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Inhibition	=	16	%	11908979
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Inhibition	=	12	%	11908979
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	99	%	11908979
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	91140	nM	11908979
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.01	ug/ml	26110443
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	11421737
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4	ug/ml	22686608
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12.5	ug/ml	22694318
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	22694318
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	18973387
NPT73	Individual Protein	Solute carrier organic anion transporter family member 1B1	Homo sapiens	Inhibition	=	29.9	%	23876004
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	200	nM	22831798
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	24709561
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	19193025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	17125229
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	>	16	ug/ml	15568762
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	Ratio	>	21		12880316
NPT2	Others	Unspecified		MIC	>	91140	nM	23738539
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	23327832
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	15300	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	16562829
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Inhibition	=	14	%	PubChem BioAssay data set
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC90	=	0.075	ug/ml	PubChem BioAssay data set
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC50	=	0.0024	ug/ml	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	100	%	26358281
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	250000	nM	19388705
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	9100	nM	22316191
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	25	ug/ml	15332839
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	=	12.5	ug/ml	20100662
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	0.1	ug/ml	19422205
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.1	ug/ml	19422205
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	25	ug/ml	20624681
NPT5246	Organism	Mycobacterium aurum	Mycobacterium aurum	MIC	=	6.3	ug/ml	20624681
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.1	ug/ml	18687007
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	290	nM	22182501
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12.5	ug/ml	20405881
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC	=	2.5	ug/ml	22921081
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	32	ug/ml	13678412
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	70000	nM	24725159
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	250000	nM	16643057
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	100	%	16643057
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	100	nM	16872131
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	96	%	11421749
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	98.42	%	16252909
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	99.01	%	16252909
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.1	ug/ml	20888765
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	GI	=	10	%	9873604
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	15566301
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC90	=	0.2	nM	18578517
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	0.5	ug/ml	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	18183025
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	18183025
NPT5832	Organism	Mycobacterium terrae	Mycobacterium terrae	MIC	=	0.1	ug/ml	18183025
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.44	ug/ml	18183025
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	500	nM	20188577
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	12.5	ug/ml	20481631
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	10998351
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC50	=	330	nM	21429632
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.65	ug/ml	22037378
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	100000	nM	22037378
NPT633	Organism	Leishmania donovani	Leishmania donovani	IC50	>	656260	nM	22037378
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	22037378
NPT73	Individual Protein	Solute carrier organic anion transporter family member 1B1	Homo sapiens	Inhibition	=	88.4	%	22037378
NPT110	Individual Protein	Cytochrome P450 2D6	Homo sapiens	Ratio IC50	>	5		22037378
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	22037378
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	22037378
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	22037378
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	360	nM	22037378
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	182310	nM	22037378
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	280	nM	22037378
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	1	ug/ml	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	200	nM	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	370	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	<=	500	nM	23398362
NPT1830	Organism	Mycobacterium marinum	Mycobacterium marinum	MIC	=	16	ug/ml	23398362
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.075	ug/ml	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	240	nM	23398362
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	23398362
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	3650	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	780	nM	18077363
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	0.8	ug/ml	22703163
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	24328283
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2.5	ug/ml	24328283
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2.5	ug/ml	15974609
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.07	ug/ml	15974609
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	729	nM	11277765
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	>	20	ug/ml	14695801
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	5690	nM	18611050
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	500	nM	23462643
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	EC90	>	5	nM	11809056
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	10425121
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	230	nM	11087594
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	98	%	11858759
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	100	ug/ml	16506833
NPT4071	Organism	Mycobacterium gordonae	Mycobacterium gordonae	MIC	=	116000	nM	16506833
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	100	%	18672931
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	22620987
NPT2	Others	Unspecified		Potency		1812.6	nM	21666868
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	16	ug/ml	23360215
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.01	ug/ml	24900585
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2000	nM	24900585
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	230	nM	10346960
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	400	nM	22617493
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	IC50	<	300	nM	19761234
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	8	ug/ml	19761234
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	19691309
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	18278869
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1	ug/ml	18278869
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	8	ug/ml	8254344
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2	ug/ml	8254344
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12.5	ug/ml	19318257
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	>	2	deltalog10CFU	1624939
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	9868159
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	IC50	=	0.05	ug/ml	22545792
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	117000	nM	22545792
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	24725159
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	15043442
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	600	nM	23910596
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	100	%	11277769
NPT2	Others	Unspecified		Potency		28727.7	nM	21885290
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	128000	nM	11473441
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	500	nM	11473441
NPT189	Cell Line	Vero	Chlorocebus aethiops	MIC	>	128000	nM	15568790
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	15568790
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	500	nM	21458279
NPT140	Organism	Artemia	Artemia	LD50	=	1074.75	ug/ml	21570834
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.36	ug/ml	20540535
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45.57	ug/ml	25987373
NPT531	Individual Protein	Nuclear receptor ROR-gamma	Mus musculus	Potency	=	14125.4	nM	26000707
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2	ug/ml	12105963
NPT86	Organism	Mycobacterium intracellulare	Mycobacterium intracellulare	MIC	=	8	ug/ml	12105963
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	62.5	ug/ml	12105963
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	5000	nM	11929285
NPT2	Others	Unspecified		Potency		30731.4	nM	11929285
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	0.03	ug/ml	19902967
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	IZ	=	23	mm	18986200
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12500	nM	PubChem BioAssay data set
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	20405925
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	18484774
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	>	500000	nM	23013292
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	18824363
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Ratio	=	1		17803266
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.75	ug/ml	19093848
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	660	nM	12027740
NPT189	Cell Line	Vero	Chlorocebus aethiops	CC50	>	7000000	nM	11575949
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2040	nM	24033131
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	24084296
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC50	<	1	ug/ml	20055495
NPT2906	Organism	Mycobacterium ulcerans	Mycobacterium ulcerans	MIC50	=	390	nM	16252909
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	FC	=	8		16252909
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	2681536
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	20614907
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	>	4	ug/ml	23395633
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	8000	nM	18163582
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.025	ug/ml	23350733
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	312	nM	19053514
NPT2	Others	Unspecified		Ratio	=	8		20799251
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.78	ug/ml	16499317
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.04	ug/ml	18507474
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	12.5	ug/ml	PubChem BioAssay data set
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC50	=	0.0023	ug/ml	18288804
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC99	=	0.13	ug/ml	20346658
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	26327273
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2	ug/ml	23634786
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	25710081
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	0.1	ug/ml	20718449
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	15104487
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	16180824
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	370	nM	23659371
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	450	nM	17338565
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	128000	nM	17338565
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1	ug/ml	22560474
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	750	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	11570	nM	PubChem BioAssay data set
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	62.5	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.2	ug/ml	20196571
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	91140	nM	25871540
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	182300	nM	23441911
NPT2	Others	Unspecified		CC50	=	199	ug/ml	23441911
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	40	nM	23441911
NPT48	Individual Protein	Lysine-specific demethylase 4D-like	Homo sapiens	Potency	=	7079.5	nM	16124776
NPT6005	Organism	Mycobacterium scrofulaceum	Mycobacterium scrofulaceum	MIC	>	0.5	ug/ml	26722868
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	230	nM	PubChem BioAssay data set
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	44.12	%	25495797
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	150	nM	24931277
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.03	ug/ml	10579870
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	128	ug/ml	10579870
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	2.19	ug/ml	23149227
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.3	ug/ml	18640035
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	EC90	=	0.03	ug/ml	23910596
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	EC99	=	0.42	ug/ml	23910596
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	IC50	=	16000	nM	23190044
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	16792412
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	5.86		16792412
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	16792412
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	90	nM	26000707
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	98	%	23031087
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	70	%	25798528
NPT63	Individual Protein	Bromodomain adjacent to zinc finger domain protein 2B	Homo sapiens	Potency		89125.1	nM	12670149
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	600	nM	12670149
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1500	nM	24273638
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	95	%	24273638
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12500	nM	24273638
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12.5	ug/ml	20704301
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	8	ug/ml	14518939
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.25	ug/ml	21623630
NPT189	Cell Line	Vero	Chlorocebus aethiops	MIC	>	128000	nM	10.1039/C3MD00097D
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	10.1039/C3MD00097D
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	200000	nM	19921834
NPT65	Cell Line	HepG2	Homo sapiens	Activity	=	99.73	%	19835393
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.625	ug/ml	19835393
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	100000	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	100000	nM	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	>	99	%	19583252
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.01	ug/ml	20971532
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC90	>	250	ug/ml	11473410
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	390	nM	18500841
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.63	ug/ml	7623030
NPT1177	Organism	Mycobacterium phlei	Mycobacterium phlei	MIC	=	4	ug/ml	9677282
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Ratio	=	1		15844965
NPT1827	Organism	Mycobacterium bovis	Mycobacterium bovis	MIC50	<	100	nM	22444684
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	22444684
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.4	ug/ml	10.1016/0960-894X(95)00346-U
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC	>	400	ug/ml	9514009
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.1	ug/ml	9514009
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC95	=	12	ug/ml	9514009
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.5	ug/ml	9514009
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	9514009
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	660	nM	19334707
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1460	nM	25856683
NPT65	Cell Line	HepG2	Homo sapiens	IC50	>	1000000	nM	25856683
NPT2739	Individual Protein	Tyrosinase	Mus musculus	Inhibition	=	102	%	25651042
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	454700	nM	17764148
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1460	nM	9548870
NPT72	Individual Protein	Solute carrier organic anion transporter family member 1B3	Homo sapiens	Inhibition	=	18.7	%	12828469
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	730	nM	12828469
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	29170	nM	15332848
NPT180	Cell Line	HCT-8	Homo sapiens	Activity	=	1.95	%	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	140	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	20491501
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	16562846
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	16562846
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	17988096
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	240	nM	17887720
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	2989	nM	PubChem BioAssay data set
NPT5832	Organism	Mycobacterium terrae	Mycobacterium terrae	MIC	=	0.1	ug/ml	PubChem BioAssay data set
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	200	nM	20624681
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	29000	nM	20624681
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	20624681
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.025	ug/ml	20674349
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	20674349
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	720	nM	26316467
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	128000	nM	12088423
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	IC50	=	650	nM	20614907
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC50	=	220	nM	20614907
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC95	=	0.1	ug/ml	19762244
NPT1107	Organism	Mycobacterium smegmatis str. MC2 155	Mycobacterium smegmatis str. MC2 155	MIC95	=	12	ug/ml	20932762
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	0.08	ug/ml	25443644
NPT100	Individual Protein	Glutaminase kidney isoform, mitochondrial	Homo sapiens	Potency		31622.8	nM	22671987
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	16643047
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.06	ug/ml	22652051
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	19555124
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	2900	nM	11421731
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	3600	nM	23993676
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	8000	nM	23993676
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	14600	nM	24968750
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	20863141
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	99.9	%	16499322
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	99	%	12398531
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>=	2	ug/ml	15730244
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>=	2	ug/ml	9134742
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	1517742
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	290	nM	22954735
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	720	nM	24050300
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	360	nM	22364566
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.025	ug/ml	17070063
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1	ug/ml	22934600
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	24601675
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	7500	nM	11086720
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	500	nM	11086720
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	17958396
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	156	nM	17958396
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	17958396
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	>	100	ug/ml	17958396
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MBC	>	1.6	ug/ml	25763602
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MBC	=	0.1	ug/ml	25763602
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	0.2	ug/ml	25763602
NPT208	Individual Protein	Cytochrome P450 1A2	Homo sapiens	AC50	=	6309.57	nM	PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	19371069
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	23647487
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	2000	nM	23634786
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	23634786
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	Inhibition	=	10	%	22512738
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	100	%	22512738
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	3.2	log CFU	23265253
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	5.5	log CFU	23043462
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	23265253
NPT53	Individual Protein	4'-phosphopantetheinyl transferase ffp	Bacillus subtilis	Potency	=	50118.7	nM	23488669
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	19453174
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	182000	nM	25710081
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	50	nM	15787444
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	15787444
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	PubChem BioAssay data set
NPT109	Individual Protein	Cytochrome P450 3A4	Homo sapiens	Ratio IC50	>	5		PubChem BioAssay data set
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	19848432
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	IC50	=	0.0023	ug/ml	17125236
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	15332867
NPT4325	Individual Protein	Pantothenate synthetase	Mycobacterium tuberculosis	IC50	>	25000	nM	20550123
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.05	ug/ml	22951040
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.023	ug/ml	20112996
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	=	150	ug/ml	19818612
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	92	%	2016726
NPT109	Individual Protein	Cytochrome P450 3A4	Homo sapiens	Potency	=	15848.9	nM	15177454
NPT2	Others	Unspecified		Ratio	=	77277		15950468
NPT2	Others	Unspecified		Ratio	=	7325		15950468
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.1	ug/ml	16246547
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4.7	ug/ml	17220425
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	0.05	ug/ml	17261619
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	>	100	ug/ml	17261619
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	17239490
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	17408811
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	17846127
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	17846127
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	17846127
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	12141853
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	100	%	9392889
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	18289735
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	17724159
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	2000	nM	17785513
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>=	2	ug/ml	19374387
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	18070960
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	FC	=	1.5		18070960
NPT2	Others	Unspecified		MIC	=	0.05	ug/ml	19815315
NPT98	Individual Protein	HERG	Homo sapiens	Potency		35481.3	nM	20044260
NPT605	Organism	Homo sapiens	Homo sapiens	Activity	=	13.3	%	20116901
NPT18	Organism	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	>	100	ug/ml	20171758
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.018	ug/ml	19949057
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	62.5	ug/ml	18227183
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	100000	nM	18285488
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	2	ug/ml	18316525
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.4	ug/ml	18316525
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	20145089
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.25	ug/ml	18180352
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	128000	nM	20385851
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	18809939
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	84	%	18809939
NPT2	Others	Unspecified		Activity	=	1.8	deltalog10CFU/ml	18809939
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.05	ug/ml	18809939
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	4	ug/ml	20350950
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC90	=	0.0078	ug/ml	18838584
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	11380	nM	18838584
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	360	nM	18838584
NPT113	Cell Line	RAW264.7	Mus musculus	GI50	=	21900000	nM	18710917
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Ratio	=	1		18725450
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC	>	500000	nM	18474583
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	GI	=	55	%	18285482
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	IC90	=	0.29	ug/ml	18490501
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC90	=	0.33	ug/ml	18505851
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.05	ug/ml	18391041
NPT240	Individual Protein	Cytochrome P450 2A6	Homo sapiens	Ki	=	60000	nM	18443122
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.75	ug/ml	19029328
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.02	ug/ml	19001116
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	<	0.1	ug/ml	19433554
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	46000	nM	19651906
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.013	ug/ml	19651906
NPT171	Cell Line	MRC5	Homo sapiens	CC50	>	10	ug/ml	19546358
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	0.5	ug/ml	19596870
NPT1177	Organism	Mycobacterium phlei	Mycobacterium phlei	MIC	=	4	ug/ml	19596870
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	95	%	19487444
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.0625	ug/ml	18591275
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.125	ug/ml	18625769
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	1000	ug/ml	20585113
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	>	100	ug/ml	18490506
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	97.3	%	18490506
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	117000	nM	18490506
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.06	ug/ml	20876371
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	0.03	ug/ml	20876374
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.125	ug/ml	19188393
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	21515059
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	IZ	=	17	mm	21440339
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	200000	nM	21558044
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	500	nM	21558044
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	100	nM	DrugMatrix in vitro pharmacology data
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	390	nM	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	128000	nM	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.5	ug/ml	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	DrugMatrix in vitro pharmacology data
NPT6010	Organism	Mycobacterium szulgai	Mycobacterium szulgai	MIC	>	0.5	ug/ml	DrugMatrix in vitro pharmacology data
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	280	nM	10.1007/s00044-011-9788-9
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	>	500	ug/ml	10.1007/s00044-009-9228-2
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	IC50	=	0.0017	ug/ml	10.1007/s00044-009-9206-8
NPT2	Others	Unspecified		Potency		11436.7	nM	23357308
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	45570	nM	23466234
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	64	%	23891184
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.025	ug/ml	Open TG-GATES in vivo data: Hematology
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	Open TG-GATES in vivo data: Hematology
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	60	nM	Open TG-GATES in vivo data: Hematology
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.1	ug/ml	Open TG-GATES in vivo data: Hematology
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	29.38	%	Open TG-GATES in vivo data: Hematology
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1820	nM	Open TG-GATES in vivo data: Hematology
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1450	nM	Open TG-GATES in vivo data: Biochemistry
NPT1108	Organism	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC	=	0.045	ug/ml	Open TG-GATES in vivo data: Biochemistry
NPT622	Individual Protein	Solute carrier organic anion transporter family member 2B1	Homo sapiens	Inhibition	=	23.8	%	Open TG-GATES in vivo data: Biochemistry
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	390	nM	Open TG-GATES in vivo data: Biochemistry
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	2	ug/ml	Open TG-GATES in vivo data: Biochemistry
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	625	nM	Open TG-GATES in vivo data: Organ Weight
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	370	nM	Open TG-GATES in vivo data: Organ Weight
NPT65	Cell Line	HepG2	Homo sapiens	Activity	=	125.47	%	DrugMatrix in vivo data: Pathology
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.05	ug/ml	DrugMatrix in vivo data: Pathology
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	145	nM	DrugMatrix in vivo data: Pathology
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	DrugMatrix in vivo data: Hematology
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	50	ug/ml	24126094
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	24601601
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	26214729
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	26191371
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4.7	ug/ml	26288696
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4.7	ug/ml	26453007
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	4.7	ug/ml	26465972
NPT65	Cell Line	HepG2	Homo sapiens	GI	=	3.51	%	26465972
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	625	nM	23701598
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.4	ug/ml	24054487
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	2	ug/ml	24054487
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	450	nM	22245048
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	>	8	ug/ml	18494522
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	17067146
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	23268694
NPT19	Organism	Escherichia coli	Escherichia coli	MIC	>	100	ug/ml	18280170
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.125	ug/ml	18280170
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	810	nM	9548870
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	850	nM	9548870
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	90	nM	24095094
NPT927	Cell Line	PBMC	Homo sapiens	IC50	=	4670000	nM	24079882
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	11975483
NPT2	Others	Unspecified		Inhibition	=	0	%	20041704
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1000	nM	20624681
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	IC90	=	0.055	ug/ml	20624681
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	PubChem BioAssay data set
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	8000	nM	3097265
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	15974609
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	45.57	ug/ml	1479376
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	2691635
NPT115	Organism	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC	=	729	nM	15497938
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.03	ug/ml	19318257
NPT5832	Organism	Mycobacterium terrae	Mycobacterium terrae	MIC	=	730	nM	16124780
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	200	nM	10843569
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	12500	nM	11575968
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	2	ug/ml	16168652
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	9804688
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	4000	nM	9249977
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	>	250000	nM	17363259
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Inhibition	=	51.62	%	17363259
NPT2	Others	Unspecified		Ratio	=	1		17363259
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	11400	nM	25856683
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	18952419
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	11000021
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	280	nM	17253859
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	>	128000	nM	17253859
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC99	=	0.098	ug/ml	21082802
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	400	nM	14695799
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.7	ug/ml	11325232
NPT602	Organism	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC	=	0.8	ug/ml	10.1007/s00044-011-9559-7
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	780	nM	10.1016/S0261-2194(02)00175-8
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	15	nM	21370392
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	19969457
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	60	nM	10.3390/70200112
NPT2903	Organism	Mycobacterium chelonae	Mycobacterium chelonae	MIC	>	400	ug/ml	23961115
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Activity	=	1.1	deltalog10CFU/ml	10.1016/j.cropro.2012.12.021
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	99	%	24582402
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	IC50	>	45570	nM	25442304
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	GI	=	100	%	19604701
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	>	98	%	23286240
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Inhibition	=	0	%	22834923
NPT2	Others	Unspecified		MIC	>	500000	nM	19245261
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1820	nM	17190450
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	13678412
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	1000	nM	13678412
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	16000	nM	20028108
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	11858756
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	=	29200	nM	22330636
NPT2	Others	Unspecified		MIC	=	0.04	ug/ml	22168134
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC50	=	0.322	ug/ml	18327911
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	120	nM	25419616
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	17190444
NPT1228	Organism	Streptococcus pyogenes	Streptococcus pyogenes	MIC	>	100	ug/ml	17190444
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	0.2	ug/ml	19835393
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	Inhibition	=	99	%	19835393
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.03	ug/ml	17844994
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	17844994
NPT927	Cell Line	PBMC	Homo sapiens	IC50	=	4670000	nM	17844994
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	4	ug/ml	17844994
NPT1176	Organism	Mycobacterium fortuitum	Mycobacterium fortuitum	MIC	=	12.5	ug/ml	17844994
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.06	ug/ml	18412396
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	430	nM	17887720
NPT790	Organism	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC	=	1.56	ug/ml	17336532
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	EC99	=	0.42	ug/ml	17958396
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC90	=	11230	nM	17958396
NPT1828	Organism	Mycobacterium kansasii	Mycobacterium kansasii	MIC	>	250000	nM	17958396
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	Activity	=	95.85	%	17958396
NPT1513	Organism	Mycobacterium avium	Mycobacterium avium	MIC	=	250000	nM	17958396
NPT88	Organism	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC	=	0.25	ug/ml	8691208

Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

● The left chart: Distribution of similarity level between NPC330326 and all remaining natural products in the NPASS database.
● The right table: Most similar natural products (Tc>=0.56 or Top200).

range	Tanimoto Coefficient
0-0.1	1250
0.1-0.2	9799
0.2-0.3	12548
0.3-0.4	4147
0.4-0.5	1576
0.5-0.6	1205
0.6-0.7	302
0.7-0.8	60
0.8-0.85	2
0.85-0.9	0
0.9-0.95	0
0.95-1	0

Similarity Score	Similarity Level	Natural Product ID
0.8222	Intermediate Similarity	NPC471589
0.8014	Intermediate Similarity	NPC114310
0.777	Intermediate Similarity	NPC105811
0.7755	Intermediate Similarity	NPC467188
0.7717	Intermediate Similarity	NPC76540
0.7698	Intermediate Similarity	NPC313823
0.7692	Intermediate Similarity	NPC235843
0.7674	Intermediate Similarity	NPC27802
0.7639	Intermediate Similarity	NPC65408
0.7616	Intermediate Similarity	NPC70406
0.7606	Intermediate Similarity	NPC322488
0.755	Intermediate Similarity	NPC313889
0.752	Intermediate Similarity	NPC83987
0.7516	Intermediate Similarity	NPC229055
0.75	Intermediate Similarity	NPC472260
0.7468	Intermediate Similarity	NPC74357
0.7451	Intermediate Similarity	NPC251391
0.745	Intermediate Similarity	NPC230085
0.745	Intermediate Similarity	NPC159630
0.7419	Intermediate Similarity	NPC213914
0.7403	Intermediate Similarity	NPC209362
0.74	Intermediate Similarity	NPC167400
0.7376	Intermediate Similarity	NPC306397
0.7324	Intermediate Similarity	NPC89490
0.7303	Intermediate Similarity	NPC112741
0.7286	Intermediate Similarity	NPC27740
0.7279	Intermediate Similarity	NPC471402
0.7279	Intermediate Similarity	NPC240136
0.7279	Intermediate Similarity	NPC297486
0.7273	Intermediate Similarity	NPC329896
0.7273	Intermediate Similarity	NPC475090
0.7273	Intermediate Similarity	NPC475105
0.7255	Intermediate Similarity	NPC123906
0.7234	Intermediate Similarity	NPC166424
0.7234	Intermediate Similarity	NPC146373
0.7234	Intermediate Similarity	NPC245244
0.7226	Intermediate Similarity	NPC91958
0.7226	Intermediate Similarity	NPC143603
0.7214	Intermediate Similarity	NPC290094
0.7194	Intermediate Similarity	NPC182570
0.7194	Intermediate Similarity	NPC48564
0.7194	Intermediate Similarity	NPC265605
0.7176	Intermediate Similarity	NPC231655
0.7153	Intermediate Similarity	NPC71236
0.7143	Intermediate Similarity	NPC291517
0.7143	Intermediate Similarity	NPC23215
0.7133	Intermediate Similarity	NPC471313
0.7133	Intermediate Similarity	NPC212125
0.7133	Intermediate Similarity	NPC471311
0.7132	Intermediate Similarity	NPC84268
0.7115	Intermediate Similarity	NPC312860
0.7115	Intermediate Similarity	NPC107287
0.7097	Intermediate Similarity	NPC473878
0.707	Intermediate Similarity	NPC263455
0.7063	Intermediate Similarity	NPC202957
0.7063	Intermediate Similarity	NPC169625
0.7055	Intermediate Similarity	NPC471322
0.7055	Intermediate Similarity	NPC324611
0.7044	Intermediate Similarity	NPC80681
0.7042	Intermediate Similarity	NPC476322
0.7019	Intermediate Similarity	NPC265100
0.7014	Intermediate Similarity	NPC165370
0.6986	Remote Similarity	NPC315320
0.6986	Remote Similarity	NPC282398
0.698	Remote Similarity	NPC29702
0.6975	Remote Similarity	NPC42372
0.6975	Remote Similarity	NPC233380
0.6972	Remote Similarity	NPC46358
0.6968	Remote Similarity	NPC100726
0.6939	Remote Similarity	NPC256893
0.6939	Remote Similarity	NPC101165
0.6937	Remote Similarity	NPC113812
0.6933	Remote Similarity	NPC114637
0.6933	Remote Similarity	NPC472288
0.6903	Remote Similarity	NPC302159
0.6879	Remote Similarity	NPC471655
0.6861	Remote Similarity	NPC473901
0.6852	Remote Similarity	NPC242116
0.6832	Remote Similarity	NPC293487
0.6829	Remote Similarity	NPC41717
0.681	Remote Similarity	NPC478184
0.6803	Remote Similarity	NPC476131
0.679	Remote Similarity	NPC473706
0.6788	Remote Similarity	NPC70949
0.6786	Remote Similarity	NPC476419
0.6783	Remote Similarity	NPC329825
0.6757	Remote Similarity	NPC69914
0.6748	Remote Similarity	NPC478185
0.6746	Remote Similarity	NPC237188
0.6744	Remote Similarity	NPC477003
0.673	Remote Similarity	NPC470679
0.673	Remote Similarity	NPC217021
0.6728	Remote Similarity	NPC474492
0.6726	Remote Similarity	NPC293216
0.6726	Remote Similarity	NPC469529
0.6711	Remote Similarity	NPC471312
0.6707	Remote Similarity	NPC273532
0.6707	Remote Similarity	NPC478182
0.669	Remote Similarity	NPC11863
0.6687	Remote Similarity	NPC470680
0.6687	Remote Similarity	NPC100104
0.6667	Remote Similarity	NPC73994
0.6647	Remote Similarity	NPC284775
0.6647	Remote Similarity	NPC157583
0.6647	Remote Similarity	NPC83774
0.6644	Remote Similarity	NPC151489
0.6628	Remote Similarity	NPC191415
0.6627	Remote Similarity	NPC478183
0.6627	Remote Similarity	NPC56233
0.6603	Remote Similarity	NPC190296
0.66	Remote Similarity	NPC82295
0.659	Remote Similarity	NPC102755
0.657	Remote Similarity	NPC61011
0.6552	Remote Similarity	NPC56856
0.6548	Remote Similarity	NPC32534
0.6541	Remote Similarity	NPC477974
0.6538	Remote Similarity	NPC476454
0.6536	Remote Similarity	NPC96102
0.6536	Remote Similarity	NPC328029
0.6532	Remote Similarity	NPC470677
0.6519	Remote Similarity	NPC159856
0.6519	Remote Similarity	NPC314372
0.6517	Remote Similarity	NPC476460
0.6509	Remote Similarity	NPC249614
0.65	Remote Similarity	NPC102664
0.6497	Remote Similarity	NPC103119
0.6494	Remote Similarity	NPC84911
0.6494	Remote Similarity	NPC314102
0.6494	Remote Similarity	NPC251722
0.6494	Remote Similarity	NPC105127
0.6486	Remote Similarity	NPC135488
0.648	Remote Similarity	NPC216550
0.6477	Remote Similarity	NPC118084
0.6474	Remote Similarity	NPC471997
0.6457	Remote Similarity	NPC110158
0.6457	Remote Similarity	NPC46895
0.6456	Remote Similarity	NPC471323
0.645	Remote Similarity	NPC91895
0.6444	Remote Similarity	NPC326422
0.6442	Remote Similarity	NPC33229
0.6429	Remote Similarity	NPC261195
0.6429	Remote Similarity	NPC29886
0.6415	Remote Similarity	NPC470440
0.641	Remote Similarity	NPC315348
0.641	Remote Similarity	NPC316811
0.641	Remote Similarity	NPC32002
0.641	Remote Similarity	NPC110126
0.641	Remote Similarity	NPC73767
0.6409	Remote Similarity	NPC135950
0.6407	Remote Similarity	NPC274981
0.6382	Remote Similarity	NPC174421
0.638	Remote Similarity	NPC200214
0.6379	Remote Similarity	NPC317010
0.6379	Remote Similarity	NPC24864
0.6375	Remote Similarity	NPC63545
0.6369	Remote Similarity	NPC230002
0.6369	Remote Similarity	NPC469761
0.6369	Remote Similarity	NPC279081
0.6369	Remote Similarity	NPC238499
0.6369	Remote Similarity	NPC469779
0.6369	Remote Similarity	NPC469767
0.6369	Remote Similarity	NPC469780
0.6369	Remote Similarity	NPC469784
0.6369	Remote Similarity	NPC469783
0.6369	Remote Similarity	NPC469768
0.6364	Remote Similarity	NPC207851
0.6364	Remote Similarity	NPC467063
0.6358	Remote Similarity	NPC240088
0.6358	Remote Similarity	NPC24678
0.6358	Remote Similarity	NPC473380
0.6358	Remote Similarity	NPC105818
0.6348	Remote Similarity	NPC278434
0.6346	Remote Similarity	NPC169433
0.634	Remote Similarity	NPC20021
0.6339	Remote Similarity	NPC106824
0.6335	Remote Similarity	NPC469811
0.6335	Remote Similarity	NPC179787
0.6335	Remote Similarity	NPC471957
0.6335	Remote Similarity	NPC201380
0.6329	Remote Similarity	NPC469766
0.6322	Remote Similarity	NPC265710
0.6322	Remote Similarity	NPC12649
0.6316	Remote Similarity	NPC213774
0.6316	Remote Similarity	NPC54214
0.6313	Remote Similarity	NPC255909
0.6307	Remote Similarity	NPC470205
0.6296	Remote Similarity	NPC321911
0.6286	Remote Similarity	NPC477042
0.6286	Remote Similarity	NPC16659
0.6282	Remote Similarity	NPC150259
0.628	Remote Similarity	NPC73952
0.628	Remote Similarity	NPC469765
0.628	Remote Similarity	NPC469760
0.628	Remote Similarity	NPC259644
0.628	Remote Similarity	NPC469763
0.628	Remote Similarity	NPC469786
0.628	Remote Similarity	NPC25008
0.6278	Remote Similarity	NPC469489
0.6278	Remote Similarity	NPC154339
0.627	Remote Similarity	NPC474767

Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

● The left chart: Distribution of similarity level between NPC330326 and all drugs/candidates.
● The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

range	Tanimoto Coefficient
0-0.1	306
0.1-0.2	1095
0.2-0.3	1115
0.3-0.4	2303
0.4-0.5	2644
0.5-0.6	1362
0.6-0.7	294
0.7-0.8	37
0.8-0.85	2
0.85-0.9	1
0.9-0.95	1
0.95-1	1

Similarity Score	Similarity Level	Drug ID	Developmental Stage
1.0	High Similarity	NPD9100	Approved
0.947	High Similarity	NPD9599	Approved
0.8741	High Similarity	NPD2061	Approved
0.8261	Intermediate Similarity	NPD272	Approved
0.8125	Intermediate Similarity	NPD175	Clinical (unspecified phase)
0.7652	Intermediate Similarity	NPD269	Clinical (unspecified phase)
0.7651	Intermediate Similarity	NPD1270	Approved
0.7639	Intermediate Similarity	NPD200	Phase 2
0.7639	Intermediate Similarity	NPD201	Phase 2
0.7616	Intermediate Similarity	NPD5965	Clinical (unspecified phase)
0.7606	Intermediate Similarity	NPD1627	Clinical (unspecified phase)
0.7603	Intermediate Similarity	NPD107	Approved
0.74	Intermediate Similarity	NPD9074	Approved
0.74	Intermediate Similarity	NPD9075	Approved
0.7376	Intermediate Similarity	NPD9080	Approved
0.7333	Intermediate Similarity	NPD751	Clinical (unspecified phase)
0.7329	Intermediate Similarity	NPD206	Clinical (unspecified phase)
0.7303	Intermediate Similarity	NPD9271	Approved
0.7286	Intermediate Similarity	NPD9357	Approved
0.7273	Intermediate Similarity	NPD9343	Clinical (unspecified phase)
0.723	Intermediate Similarity	NPD203	Clinical (unspecified phase)
0.7205	Intermediate Similarity	NPD1292	Clinical (unspecified phase)
0.7194	Intermediate Similarity	NPD270	Clinical (unspecified phase)
0.7194	Intermediate Similarity	NPD271	Approved
0.7194	Intermediate Similarity	NPD268	Approved
0.7183	Intermediate Similarity	NPD9583	Approved
0.7176	Intermediate Similarity	NPD9099	Clinical (unspecified phase)
0.7176	Intermediate Similarity	NPD9098	Phase 3
0.7172	Intermediate Similarity	NPD9726	Discontinued
0.7135	Intermediate Similarity	NPD1905	Clinical (unspecified phase)
0.7134	Intermediate Similarity	NPD4883	Approved
0.7133	Intermediate Similarity	NPD9284	Approved
0.7133	Intermediate Similarity	NPD1598	Discontinued
0.7133	Intermediate Similarity	NPD991	Phase 2
0.7133	Intermediate Similarity	NPD992	Clinical (unspecified phase)
0.7114	Intermediate Similarity	NPD2896	Discontinued
0.7066	Intermediate Similarity	NPD1618	Phase 2
0.7063	Intermediate Similarity	NPD5400	Approved
0.7029	Intermediate Similarity	NPD1851	Clinical (unspecified phase)
0.7029	Intermediate Similarity	NPD9392	Approved
0.7029	Intermediate Similarity	NPD9396	Approved
0.7019	Intermediate Similarity	NPD1545	Discontinued
0.6994	Remote Similarity	NPD1343	Approved
0.6986	Remote Similarity	NPD9206	Approved
0.6986	Remote Similarity	NPD9207	Approved
0.6981	Remote Similarity	NPD820	Phase 3
0.6966	Remote Similarity	NPD1031	Discontinued
0.6964	Remote Similarity	NPD1291	Clinical (unspecified phase)
0.6964	Remote Similarity	NPD3927	Phase 2
0.6933	Remote Similarity	NPD6446	Discontinued
0.6923	Remote Similarity	NPD1783	Clinical (unspecified phase)
0.6912	Remote Similarity	NPD4824	Approved
0.6912	Remote Similarity	NPD4823	Approved
0.6897	Remote Similarity	NPD2119	Approved
0.6897	Remote Similarity	NPD2118	Approved
0.6894	Remote Similarity	NPD6454	Clinical (unspecified phase)
0.6884	Remote Similarity	NPD60	Approved
0.686	Remote Similarity	NPD5820	Clinical (unspecified phase)
0.6842	Remote Similarity	NPD1096	Discontinued
0.6842	Remote Similarity	NPD7564	Discontinued
0.6831	Remote Similarity	NPD9598	Discontinued
0.681	Remote Similarity	NPD3583	Phase 2
0.6803	Remote Similarity	NPD9305	Clinical (unspecified phase)
0.6797	Remote Similarity	NPD1395	Clinical (unspecified phase)
0.6792	Remote Similarity	NPD180	Clinical (unspecified phase)
0.679	Remote Similarity	NPD2511	Approved
0.6786	Remote Similarity	NPD8840	Approved
0.6765	Remote Similarity	NPD2479	Phase 3
0.6765	Remote Similarity	NPD2481	Approved
0.6763	Remote Similarity	NPD4426	Clinical (unspecified phase)
0.6757	Remote Similarity	NPD3476	Approved
0.6757	Remote Similarity	NPD3475	Approved
0.6732	Remote Similarity	NPD569	Clinical (unspecified phase)
0.673	Remote Similarity	NPD510	Phase 1
0.6711	Remote Similarity	NPD9506	Approved
0.6711	Remote Similarity	NPD803	Phase 1
0.671	Remote Similarity	NPD1427	Clinical (unspecified phase)
0.6705	Remote Similarity	NPD4336	Clinical (unspecified phase)
0.6688	Remote Similarity	NPD2222	Discontinued
0.6687	Remote Similarity	NPD1917	Discontinued
0.6667	Remote Similarity	NPD1995	Approved
0.6667	Remote Similarity	NPD1380	Discovery
0.6667	Remote Similarity	NPD1994	Approved
0.6667	Remote Similarity	NPD748	Clinical (unspecified phase)
0.6667	Remote Similarity	NPD1993	Approved
0.6647	Remote Similarity	NPD2753	Discontinued
0.6646	Remote Similarity	NPD4702	Approved
0.6646	Remote Similarity	NPD4703	Approved
0.6646	Remote Similarity	NPD2809	Approved
0.6646	Remote Similarity	NPD6771	Discontinued
0.6645	Remote Similarity	NPD792	Discontinued
0.6644	Remote Similarity	NPD715	Phase 3
0.6628	Remote Similarity	NPD4011	Clinical (unspecified phase)
0.6623	Remote Similarity	NPD4028	Approved
0.6623	Remote Similarity	NPD4030	Approved
0.6623	Remote Similarity	NPD4804	Approved
0.6623	Remote Similarity	NPD3944	Approved
0.6623	Remote Similarity	NPD768	Clinical (unspecified phase)
0.6623	Remote Similarity	NPD3942	Approved
0.6623	Remote Similarity	NPD945	Clinical (unspecified phase)
0.6623	Remote Similarity	NPD4029	Approved
0.6622	Remote Similarity	NPD1095	Clinical (unspecified phase)
0.6613	Remote Similarity	NPD6459	Phase 2
0.6606	Remote Similarity	NPD5088	Discontinued
0.6603	Remote Similarity	NPD3717	Discontinued
0.66	Remote Similarity	NPD809	Discontinued
0.6592	Remote Similarity	NPD7024	Clinical (unspecified phase)
0.659	Remote Similarity	NPD7401	Clinical (unspecified phase)
0.6588	Remote Similarity	NPD3238	Discontinued
0.6581	Remote Similarity	NPD1649	Discontinued
0.6579	Remote Similarity	NPD2142	Approved
0.6579	Remote Similarity	NPD2141	Approved
0.6579	Remote Similarity	NPD2140	Approved
0.6573	Remote Similarity	NPD4376	Phase 3
0.6564	Remote Similarity	NPD1192	Clinical (unspecified phase)
0.6561	Remote Similarity	NPD3813	Approved
0.6538	Remote Similarity	NPD1382	Phase 2
0.6538	Remote Similarity	NPD1722	Approved
0.6538	Remote Similarity	NPD4805	Approved
0.6538	Remote Similarity	NPD1383	Phase 3
0.6536	Remote Similarity	NPD198	Clinical (unspecified phase)
0.6534	Remote Similarity	NPD4988	Discontinued
0.6529	Remote Similarity	NPD5322	Clinical (unspecified phase)
0.6527	Remote Similarity	NPD5636	Discontinued
0.6527	Remote Similarity	NPD5611	Phase 2
0.6527	Remote Similarity	NPD4174	Clinical (unspecified phase)
0.6527	Remote Similarity	NPD4643	Clinical (unspecified phase)
0.6517	Remote Similarity	NPD6180	Clinical (unspecified phase)
0.65	Remote Similarity	NPD5855	Phase 3
0.65	Remote Similarity	NPD5853	Phase 3
0.6497	Remote Similarity	NPD2007	Clinical (unspecified phase)
0.6497	Remote Similarity	NPD2006	Phase 2
0.6478	Remote Similarity	NPD7469	Discontinued
0.6478	Remote Similarity	NPD6148	Clinical (unspecified phase)
0.6467	Remote Similarity	NPD1568	Clinical (unspecified phase)
0.6464	Remote Similarity	NPD7027	Phase 3
0.6464	Remote Similarity	NPD6226	Phase 3
0.6461	Remote Similarity	NPD5685	Approved
0.6461	Remote Similarity	NPD5686	Approved
0.6457	Remote Similarity	NPD3607	Clinical (unspecified phase)
0.6456	Remote Similarity	NPD1352	Discontinued
0.6446	Remote Similarity	NPD4384	Clinical (unspecified phase)
0.6444	Remote Similarity	NPD460	Discontinued
0.6438	Remote Similarity	NPD1661	Suspended
0.6433	Remote Similarity	NPD5020	Approved
0.6429	Remote Similarity	NPD490	Clinical (unspecified phase)
0.6429	Remote Similarity	NPD5446	Phase 2
0.6416	Remote Similarity	NPD8304	Clinical (unspecified phase)
0.641	Remote Similarity	NPD2073	Approved
0.641	Remote Similarity	NPD2068	Approved
0.641	Remote Similarity	NPD2070	Approved
0.641	Remote Similarity	NPD786	Approved
0.641	Remote Similarity	NPD2075	Approved
0.641	Remote Similarity	NPD2069	Approved
0.641	Remote Similarity	NPD2071	Approved
0.641	Remote Similarity	NPD2072	Approved
0.641	Remote Similarity	NPD2074	Approved
0.6404	Remote Similarity	NPD7175	Phase 1
0.6398	Remote Similarity	NPD1183	Approved
0.6395	Remote Similarity	NPD6471	Clinical (unspecified phase)
0.6395	Remote Similarity	NPD7402	Clinical (unspecified phase)
0.6395	Remote Similarity	NPD6044	Discontinued
0.6393	Remote Similarity	NPD1982	Phase 1
0.6389	Remote Similarity	NPD981	Phase 2
0.6374	Remote Similarity	NPD4848	Phase 1
0.6359	Remote Similarity	NPD7049	Clinical (unspecified phase)
0.6359	Remote Similarity	NPD5854	Approved
0.6359	Remote Similarity	NPD2405	Phase 3
0.6354	Remote Similarity	NPD1173	Approved
0.6353	Remote Similarity	NPD5436	Phase 1
0.6348	Remote Similarity	NPD2770	Discontinued
0.6331	Remote Similarity	NPD3929	Clinical (unspecified phase)
0.6328	Remote Similarity	NPD5555	Phase 1
0.6325	Remote Similarity	NPD704	Clinical (unspecified phase)
0.6319	Remote Similarity	NPD4641	Discontinued
0.6319	Remote Similarity	NPD3262	Approved
0.6303	Remote Similarity	NPD2748	Clinical (unspecified phase)
0.6298	Remote Similarity	NPD5505	Discontinued
0.6298	Remote Similarity	NPD7098	Clinical (unspecified phase)
0.6298	Remote Similarity	NPD4922	Phase 2
0.6296	Remote Similarity	NPD2430	Phase 2
0.629	Remote Similarity	NPD5017	Discontinued
0.6289	Remote Similarity	NPD4510	Discontinued
0.6284	Remote Similarity	NPD2289	Phase 3
0.6284	Remote Similarity	NPD2290	Phase 3
0.628	Remote Similarity	NPD2012	Clinical (unspecified phase)
0.6279	Remote Similarity	NPD1958	Clinical (unspecified phase)
0.6277	Remote Similarity	NPD4299	Phase 1
0.627	Remote Similarity	NPD2548	Clinical (unspecified phase)
0.6258	Remote Similarity	NPD7913	Clinical (unspecified phase)
0.6257	Remote Similarity	NPD7187	Phase 2
0.625	Remote Similarity	NPD8026	Phase 1
0.625	Remote Similarity	NPD1918	Clinical (unspecified phase)
0.6243	Remote Similarity	NPD4559	Clinical (unspecified phase)
0.6243	Remote Similarity	NPD2336	Approved
0.6242	Remote Similarity	NPD4436	Clinical (unspecified phase)
0.6242	Remote Similarity	NPD1328	Approved
0.6242	Remote Similarity	NPD5358	Clinical (unspecified phase)
0.6235	Remote Similarity	NPD2089	Clinical (unspecified phase)
0.623	Remote Similarity	NPD7618	Phase 3

Structure

External Identifiers

PubChem CID	3767
ChEMBL	CHEMBL64
ZINC

Physicochemical Properties

Molecular Weight:	137.06
ALogP:	-1.2303
MLogP:	1.68
XLogP:	-0.571
# Rotatable Bonds:	3
Polar Surface Area:	68.01
# H-Bond Aceptor:	4
# H-Bond Donor:	2
# Rings:	1
# Heavy Atoms:	10

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